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1

Hayatou, Zineb. "Appropriation d'une prothèse de membre supérieur chez la sourisEmbodiment of a forelimb prosthesis in the mouse model." Electronic Thesis or Diss., université Paris-Saclay, 2024. http://www.theses.fr/2024UPASL045.

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Les recherches sur l'appropriation corporelle sont essentielles pour le développement des prothèses. En effet, l'incapacité à s’approprier une prothèse entraîne inconfort et douleurs fantômes chez de nombreux patients. Pour améliorer l'acceptation et l'utilisation des prothèses, il est donc crucial de comprendre et de pouvoir manipuler ce sens d’appropriation. Le modèle souris présente de nombreux avantages pour ces recherches grâce à ses comportements riches de membres supérieurs ainsi qu’aux technologies optogénétiques disponibles d’abord chez ce modèle. Ces techniques permettent une explora
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Lacuey, Lecumberri Nuria. "Human autonomic and respiratory responses to direct cortical electrical stimulation." Doctoral thesis, Universitat Autònoma de Barcelona, 2018. http://hdl.handle.net/10803/666840.

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Los pacientes con epilepsia son bien conocidos por tener un mayor riesgo de muerte súbita inesperada. El riesgo de muerte súbita inesperada en pacientes con epilepsia (SUDEP) varía de 0,35 a 2,3 por cada 1000 personas por año en las poblaciones de base comunitaria, a 6,3 a 9,3 en los candidatos a cirugía para la epilepsia. Los mecanismos agónicos precisos que desencadenan SUDEP son desconocidos, aunque la evidencia reciente del estudio de unidades de monitoreo de Epilepsia (MORTEMUS) apunta al colapso combinado respiratorio y cardiovascular que conduce al fatal evento. Los signos adversos del
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Austin, Vivienne Catherine Marie. "fMRI investigation of a model of direct cortical stimulation in rodent brain." Thesis, University of Oxford, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.275373.

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Mottolese, Carmine. "Étude per-opératoire par stimulation électrique directe des représentation sensorimotrices corticales et cérébelleuses chez l'homme." Thesis, Lyon 1, 2013. http://www.theses.fr/2013LYO10303.

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Durant les dernières décennies, le système moteur a été largement étudié. Pourtant, bien des zones d'incertitudes persistent concernant d'une part la nature des circuits neuronaux de haut niveau impliqués dans l'émergence des sentiments d'intention ou de conscience motrice et d'autre part l'organisation des structures cérébrales de bas-niveau impliquées dans l'expression de ces sentiments. Il a été suggéré que le cortex pariétal et l'aire motrice supplémentaire pourraient jouer un rôle dans la génération des intentions motrices, alors que le cortex prémoteur pourrait plutôt sous-tendre la cons
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Trebaul, Lena. "Développement d'outils de traitement du signal et statistiques pour l'analyse de groupe des réponses induites par des stimulations électriques corticales directes chez l'humain." Thesis, Université Grenoble Alpes (ComUE), 2017. http://www.theses.fr/2017GREAS045/document.

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Introduction : La stimulation électrique directe basse fréquence est pratiquée sur des patients épileptiques pharmaco-résistants implantés avec des électrodes profondes. Elle induit de potentiels évoqués cortico-corticaux (PECC) qui permettent d’estimer la connectivité in vivo et ont permis de caractériser des réseaux locaux. Pour estimer la connectivité à l’échelle du cortex, le projet multicentrique F-TRACT vise à rassembler plusieurs centaines de patients dans une base de données pour proposer un atlas probabiliste de tractographie fonctionnelle.Méthodes : La construction de la base de donn
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Bation, Rémy. "Stimulation électrique par courant continu (tDCS) dans les Troubles Obsessionnels et Compulsifs résistants : effets cliniques et électrophysiologiques." Thesis, Lyon, 2018. http://www.theses.fr/2018LYSE1344/document.

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Les Troubles Obsessionnels et Compulsifs (TOC) sont un trouble mental sévère et fréquemment résistant. La physiopathologie du trouble se caractérise par des anomalies au sein des boucle cortico-striato-thalamo-cortical entrainant une hyper-activité du cortex orbito-frontal, du cortex cingulaire antérieur, du putamen. Au cours des dernières années, des anomalies structurales et fonctionnelles du cervelet ont de plus été mise en évidence dans les TOC venant compléter le modèle existant.Nous avons mise au point un protocole de traitement par tDCS ciblant le cortex orbito-frontal gauche et le cerv
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Floyd, John Tyler. "Lower Extremity Transcranial Direct Current Stimulation (TDCS)| The Effect of Montage and Medium on Cortical Excitability." Thesis, University of Central Arkansas, 2018. http://pqdtopen.proquest.com/#viewpdf?dispub=10686422.

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<p> The dissertation consists of three parts. The first part is a systematic review of the literature regarding transcranial direct current stimulation (tDCS) and its effects on lower extremity motor behaviors and corticospinal excitability of the lower extremity representation of the motor cortex in healthy subjects. The second part investigates how different electrode montages and electrode conductance mediums affect corticospinal excitability of the tibialis anterior (TA) representation of the motor cortex in healthy subjects. The third part studies how different electrode montage and elect
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8

Amadi, Ugwechi. "Transcranial stimulation to enhance cortical plasticity in the healthy and stroke-affected motor system." Thesis, University of Oxford, 2012. http://ora.ox.ac.uk/objects/uuid:bb27ac6f-a79d-459a-b5a0-e9a209ac7132.

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This thesis investigated transcranial direct current stimulation (tDCS) as applied to the motor system, and its ability to modulate underlying cortical processes and resultant motor behaviours. Functional magnetic resonance imaging (fMRI) and transcranial magnetic stimulation (TMS) were employed to assess the extent to which tDCS induces quantifiable changes in neural structure and function in controls and stroke patients. Modifications in the connectivity of intrinsic functional networks following tDCS application were examined using resting state fMRI. Polarity-specific changes were found: c
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Qin, Jing. "The effects of transcranial direct current stimulation (tDCS) on balance control in Parkinson's disease (PD)." Thesis, Queensland University of Technology, 2021. https://eprints.qut.edu.au/211438/1/Jing_Qi_Thesis.pdf.

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10

Huang, Austin. "Cortical Stimulation Mapping of Heschl’s Gyrus in the Auditory Cortex for Tinnitus Treatment." Scholarship @ Claremont, 2019. https://scholarship.claremont.edu/cmc_theses/2073.

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Tinnitus is the perception of sound in the absence of an actual sound stimulus. Recent developments have shifted the focus to the central nervous system and the neural correlate of tinnitus. Broadly, tinnitus involves cortical map rearrangement, pathological neural synchrony, and increased spontaneous firing rates. Various cortical regions, such as Heschl’s gyrus in the auditory cortex, have been found to be associated with different aspects of tinnitus, such as perception and loudness. I propose a cortical stimulation mapping study of Heschl’s gyrus using a depth and subdural electrode montag
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11

Lemaréchal, Jean-Didier. "Estimation des propriétés dynamiques des réseaux cérébraux à large échelle par modèles de masse neurale de potentiels évoqués cortico-corticaux Comparison of two integration methods for dynamic causal modeling of electrophysiological data. NeuroImage An atlas of neural parameters based on dynamic causal modeling of cortico-cortical evoked potentials." Thesis, Université Grenoble Alpes, 2020. http://www.theses.fr/2020GRALS007.

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Ce travail de thèse porte sur la modélisation des potentiels évoqués cortico-corticaux (PECCs) induits par stimulation électrique intracérébrale lors de procédures de chirurgie de l’épilepsie en stéréo-électroencéphalographie. Nous utilisons pour cela des modèles de masse neurale de type modèles causaux dynamiques (Dynamic causal modeling, DCM).Dans un premier temps, nous démontrons l'importance d'utiliser une technique d'intégration précise pour résoudre le système d'équations différentielles formalisant la dynamique du modèle (Lemaréchal et al., 2018), en particulier pour une estimation préc
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Gordon, Pedro Caldana. "Excitabilidade cortical motora como preditora de resposta na esquizofrenia." Universidade de São Paulo, 2018. http://www.teses.usp.br/teses/disponiveis/5/5169/tde-14022019-084004/.

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O desenvolvimento da estimulação magnética transcraniana (EMT) permitiu o estudo de potenciais evocados motores eliciados pela estimulação direta do córtex cerebral de forma não-invasiva. Foi observado que diferentes paradigmas de estimulação cortical por EMT apresentam diferentes padrões de resposta, que posteriormente foram associados ao funcionamento de circuitos corticais GABAérgicos e glutamatérgicos do córtex motor, compondo assim índices de excitabilidade cortical motora (ECM). Ademais, desvios da normalidade de tais índices foram encontrados em diversas condições clínicas, incluindo tr
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13

Usami, Kiyohide. "Sleep modulates cortical connectivity and excitability in humans: direct evidence from neural activity induced by single-pulse electrical stimulation." Kyoto University, 2015. http://hdl.handle.net/2433/202800.

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14

Kan, Benjamin. "Effect of transcranial direct current stimulation (tDCS) on maximal voluntary isometric strength and endurance of the elbow flexors." Thesis, Edith Cowan University, Research Online, Perth, Western Australia, 2011. https://ro.ecu.edu.au/theses/375.

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The present study investigated the effects of transcranial direct current stimulation (tDCS) on maximal voluntary contraction strength (MVC) and the time to failure (TTF) of an isometric muscle endurance test of the elbow flexors. Prior to the main study, the test-retest reliability of MVC and TTF measures was investigated using 10 men (33.2 ± 9.4 y) for the measurements separated by 60 min (within-day) and one week (between-day). Coefficient of variation (CV), Intraclass correlation (ICC, R), a paired t-test and the Bland-Altman plots revealed that TTF at 30% MVC task was reliable, and was ab
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15

Kobayashi, Katsuya. "Different Mode of Afferents Determines the Frequency Range of High Frequency Activities in the Human Brain: Direct Electrocorticographic Comparison between Peripheral Nerve and Direct Cortical Stimulation." Kyoto University, 2015. http://hdl.handle.net/2433/202676.

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16

Thompson, Jacqueline Marie. "Influences of visuospatial mental processes and cortical excitability on numerical cognition and learning." Thesis, University of Oxford, 2014. https://ora.ox.ac.uk/objects/uuid:6f11adba-5ff3-4f3b-b254-fda6ab0ed5a7.

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Numerical cognition has been shown to share many aspects of spatial cognition, both behavioural and neurological. However, it is unclear whether a particular type of spatial cognition, visuospatial mental imagery (VSMI), may play a role in symbolic numerical representation. In this thesis, I first show that mental rotation, a form of VSMI, is related to two measures of basic numerical representation. I then show that number-space synaesthesia (NSS), a rare type of VSMI involving visualised spatial layouts for numbers, does not show an advantage in mental rotation, but shows interference in num
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Tarragó, Maria da Graça Lopes. "Efeito da estimulação transcraniana de corrente contínua e da eletroestimulação intramuscular na dor, na capacidade funcional e na excitabilidade cortical de pacientes com osteoartrite." reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2017. http://hdl.handle.net/10183/171384.

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Introdução: A osteoartrite de joelhos (KOA) apresenta alta prevalência, principalmente em mulheres. Com o envelhecimento da população esta prevalência irá aumentar. Os tratamentos conservadores apresentam limitada eficácia em expressivo número de pacientes no curso do tratamento . A cirurgia de protetização apresenta altos custos, possibilidade de complicações pós-operatórias graves e ainda que a correção anatômica seja perfeita, em torno de 20% dos pacientes persistem com dor crônica pós-operatória. Portanto, é preciso avançar no conhecimento dos mecanismos fisiopatológicos e estudar novas ab
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Shimotake, Akihiro. "Direct Exploration of the Role of the Ventral Anterior Temporal Lobe in Semantic Memory: Cortical Stimulation and Local Field Potential Evidence From Subdural Grid Electrodes." Kyoto University, 2015. http://hdl.handle.net/2433/202675.

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Jamil, Asif [Verfasser], Michael [Akademischer Betreuer] Nitsche, Melanie [Gutachter] Wilke, and Dario [Gutachter] Farina. "Optimizing the efficacy of transcranial direct current stimulation on cortical neuroplasticity based on a neurovascular coupling model / Asif Jamil ; Gutachter: Melanie Wilke, Dario Farina ; Betreuer: Michael Nitsche." Göttingen : Niedersächsische Staats- und Universitätsbibliothek Göttingen, 2017. http://d-nb.info/1126724750/34.

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Zamora, Francis Carolina. "Effects of cathodal transcranial direct current stimulation on cortical spreading depression." Thesis, 2017. https://hdl.handle.net/2144/24024.

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The purpose of this study was to examine the effects of cathodal transcranial direct current stimulation (tDCS) on cortical spreading depression (CSD) in the rat cerebral cortex. CSD is a propagating wave of hyperexcitability that occurs in a number of neurological disorders characterized by excess cerebral excitability such as migraine, acute brain injury, or stroke. Since tDCS is a non-invasive method capable of inducing polarity-dependent changes in cortical excitability, we hypothesized that cathodal stimulation would prevent, attenuate, or change the characteristics of CSD. Forty Sprag
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Cherukuri, Sahitya Priya. "The effects of anodal transcranial direct current stimulation on cortical spreading depression." Thesis, 2017. https://hdl.handle.net/2144/23766.

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Cortical spreading depression (CSD) is a depolarizing wave that travels through the cerebral cortex, and is followed by an inhibition of cortical activity. The propagation of CSD elicits metabolic challenges in tissue that may be irrecoverable in an ischemic brain, and thus has implications in neurological disease. Limiting the incidence of CSD may be instrumental in limiting the extent of neuronal damage following brain injury. Transcranial direct current stimulation (tDCS) is a form of brain stimulation that alters the level of cortical activity. Anodal tDCS, which increases cortical excitab
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Chang, Andrew Stanford. "Electrophysiological analysis of transcranial direct current stimulation and its effect on cortical spreading depression." Thesis, 2016. https://hdl.handle.net/2144/16812.

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Transcranial direct current stimulation (TDCS) allows for the noninvasive modulation of cortical activity. In this study, the effects of cathodal and anodal TDCS treatment on baseline activity in the motor cortex of rats were investigated via translaminar electroencephalogram (EEG) recording and power spectral density analysis. Treatment with low intensity anodal TDCS for five minutes was found to increase delta and theta frequency cortical activity during and for up to five minutes following treatment. This study also assessed the interaction of TDCS with the phenomenon of cortical spread
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Cheng, Wei-Jing, and 鄭崴璟. "Effects of Transcranial Direct Electrical Stimulation Combined with Neuromuscular Electrical Stimulation on Cortical Excitability in Patients with Stroke: a Transcranial Magnetic Stimulation Preliminary Study." Thesis, 2018. http://ndltd.ncl.edu.tw/handle/qx98pq.

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碩士<br>高雄醫學大學<br>物理治療學系碩士班<br>106<br>Background and purpose:Previous studies have demonstrated the transcranial direct current stimulation (tDCS) and neuromuscular electrical stimulation (NMES) intervention on motor recovery of upper extremity (UE) of stroke patients are evident, but changes of cortical excitability by combination of two neuromodulation instruments are still unknown. The aim of this study was to investigate the effects of tDCS combined with NMES on excitability of motor cortex in patients with stroke. Methods:Twenty three patients with first-ever ischemic stroke for more than s
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Labbé, Sara. "Les effets de la stimulation électrique transcrânienne à courant direct appliquée au cortex somatosensoriel primaire sur la perception vibrotactile." Thèse, 2015. http://hdl.handle.net/1866/13119.

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La stimulation électrique transcrânienne à courant direct (tDCS) est une technique non invasive de neuromodulation qui modifie l’excitabilité corticale via deux grosses électrodes de surface. Les effets dépendent de la polarité du courant, anodique = augmentation de l’excitabilité corticale et cathodique = diminution. Chez l’humain, il n’existe pas de consensus sur des effets de la tDCS appliquée au cortex somatosensoriel primaire (S1) sur la perception somesthésique. Nous avons étudié la perception vibrotactile (20 Hz, amplitudes variées) sur le majeur avant, pendant et après la tDCS appliqu
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Jamil, Asif. "Optimizing the efficacy of transcranial direct current stimulation on cortical neuroplasticity based on a neurovascular coupling model." Doctoral thesis, 2017. http://hdl.handle.net/11858/00-1735-0000-0023-3DBC-2.

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Reddy, Vamsee. "Electromagnetic interventions as a therapeutic approach to spreading depression." Thesis, 2017. https://hdl.handle.net/2144/23842.

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Spreading depression (SD) is a slow propagating wave of depolarization that can spread throughout the cortex in the event of brain injury or any general energy failure of the brain. Massive cellular depolarization causes enormous ionic and water shifts and silences synaptic transmission in the affected tissue. Large amounts of energy are required to restore ionic gradients and are not always met. When these energetic demands are not met, brain tissue damage can occur. The exact mechanism behind initiation and propagation of SD are unknown, but a general model is known. It may be possible to pr
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Soares, Foerster Aguida. "Optimization of transcranial direct current stimulation (tDCS) to modulate lower limb motor network in healthy humans." Doctoral thesis, 2018. http://hdl.handle.net/11858/00-1735-0000-002E-E498-D.

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Sturhan, Cornelia-Carmen. "Akute Auswirkungen transkranieller Gleichstromstimulation auf Parameter kortikaler Erregbarkeit." Doctoral thesis, 2012. http://hdl.handle.net/11858/00-1735-0000-000D-EFE2-3.

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