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1

Hamid, Muhammad Fadhli Ab, May May Choo, Nurliza Khaliddin, and Norlina Mohd Ramli. "Evans syndrome in child with sudden blindness." Malaysian Journal of Ophthalmology 3, no. 1 (2021): 64–68. http://dx.doi.org/10.35119/myjo.v3i1.165.

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A 3-year-old girl presented with sudden onset of bilateral vision loss on waking up from sleep. There had been no associated eye pain, eye redness, fever or history of trauma in the days leading up to the presentation. She had been diagnosed with Evans syndrome at the age of 18 months and started on a regular dose of oral prednisolone under regular follow-up at the paediatric clinic. Upon presentation, her visual acuity was light perception bilaterally, with relative afferent pupillary defect in the right eye and sluggish pupils bilaterally. Bilateral fundus examination showed normal macula an
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Iqbal, Roshan, and Saugata Das. "Cortical blindness: diagnostic issues in sudden bilateral visual loss." Progress in Neurology and Psychiatry 27, no. 3 (2023): 37–39. http://dx.doi.org/10.1002/pnp.803.

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Cortical blindness is defined as bilateral visual loss due to disruption of the visual pathways beyond the lateral geniculate body. Visual disturbance as a result of cortical lesion can manifest in different ways. Anton's syndrome is one of the manifestations of cortical blindness, which presents as denial of loss of vision associated with confabulation in the setting of obvious visual loss. This case illustrates the challenges of diagnosing cortical blindness in the emergency setting.
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Aziz, Faradatul Aisyah Abdul, Tuan Hazri Tuan Mat, Nurhamiza Buang, Nor Idahriani Muhd Nor, and Jemaima Che Hamzah. "Contrast-induced transient cortical blindness." Indian Journal of Ophthalmology - Case Reports 4, no. 3 (2024): 616–18. http://dx.doi.org/10.4103/ijo.ijo_412_23.

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A 58-year-old Malay man with a history of ischemic heart disease, well-controlled diabetes mellitus, and hypertension presented with sudden loss of vision after he underwent angiogram (cardiac catheterization) with contrast. Post-angiogram, his visual acuity deteriorated gradually to no perception of light bilaterally within 1 h duration. Clinically, there was no new intraocular pathology and neurologic examination was normal. An urgent noncontract computed tomography (CT) scan of the brain showed the presence of contrast in the venous sinuses but no obvious acute intracranial hemorrhage. Bila
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Pedro-Egbe, Chinyere. "Sudden Bilateral Blindness Following Massive Uterine Bleeding: Reports of 2 Cases." British Journal of Medicine and Medical Research 2, no. 2 (2012): 254–59. http://dx.doi.org/10.9734/bjmmr/2012/1000.

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Nimesh, Nivedita, Sanjeev Kumar Verma, and Sanjiv Kumar Gupta. "Cortical blindness due to cerebral infarct in advanced pancreatic cancer." BMJ Case Reports 12, no. 7 (2019): e223843. http://dx.doi.org/10.1136/bcr-2017-223843.

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A 65-year-old man, a known case of advanced pancreatic cancer on cisplatin and gemcitabine-based chemotherapy, presented with sudden bilateral painless loss of vision with altered sensorium. Clinical examination showed a normal pupillary light reaction, normal anterior segment and normal fundus. MRI brain showed bilateral parieto-occipital infarct. This report highlights the incidence of cortical blindness due to thromboembolism at the cerebral level in pancreatic cancer. Cerebral ischaemic events occur at an advanced stage of pancreatic cancer already diagnosed at stroke onset and portend a p
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Youn, Michelle, Jeong Hyun Seo, Byung-Kun Kim, Ra Gyoung Yoon, and Eun Hye Jung. "Transient Cortical Blindness Following Cervical Transforaminal Epidural Injection." Journal of the Korean Ophthalmological Society 63, no. 11 (2022): 953–57. http://dx.doi.org/10.3341/jkos.2022.63.11.953.

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Purpose: To report a case of transient cortical blindness following cervical transforaminal epidural injection.Case summary: A 58-year-old diabetic and hypertensive male was referred to the ophthalmology department with sudden-onset bilateral visual disturbances after cervical transforaminal epidural injection for neck pain. During the procedure, an intravascular contrast medium was injected into the left vertebral artery. Immediately after the injection, the patient complained of bilateral visual disturbances, mild headache, and dizziness. Twelve hours after the procedure, his visual acuity w
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7

Sidhu, Amitouj S., Charles E. L. Walker, Thomas D. Riisfeldt, et al. "Successful Management of Acute Streptococcal Meningoencephalitis Complicated by Bilateral Third-Nerve Palsies, Wall-Eyed Bilateral Internuclear Ophthalmoplegia, Blindness, and Deafness: Case Report." Case Reports in Ophthalmology 15, no. 1 (2024): 430–36. http://dx.doi.org/10.1159/000538821.

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Introduction: Streptococcal meningoencephalitis (SME) is a rare, and frequently lethal, acute infection, and inflammation of the central nervous system parenchyma, with associated meningeal involvement. Bacterial meningoencephalitis is generally associated with high rates of morbidity and mortality, despite available antimicrobial and corticosteroid treatments. While Streptococcus pneumoniae is well recognised to cause bacterial meningitis, direct extension into the central nervous system parenchyma is rare. Case Presentation: A previously well 49-year-old man presented with sudden onset sever
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Surges, Rainer, Sandra Beck, Wolf-Dirk Niesen, Cornelius Weiller, and Michel Rijntjes. "Sudden bilateral blindness in Wernicke's encephalopathy: Case report and review of the literature." Journal of the Neurological Sciences 260, no. 1-2 (2007): 261–64. http://dx.doi.org/10.1016/j.jns.2007.04.005.

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Murphy, Lauren, and Gerard Carroll. "Acute bilateral retinal artery occlusion causing sudden blindness in 25-year-old patient." American Journal of Emergency Medicine 36, no. 6 (2018): 1124.e3–1124.e4. http://dx.doi.org/10.1016/j.ajem.2018.03.013.

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Mladenovski, Igor, Milan Mladenovski, Plamen Stoev, Stanislava Vasilkova, and Maya Danovska. "CORTICAL BLINDNESS DUE TO BILATERAL STROKES – A CASE REPORT OF ANTON SYNDROME." Journal of IMAB - Annual Proceeding (Scientific Papers) 29, no. 2 (2023): 5006–8. http://dx.doi.org/10.5272/jimab.2023292.5006.

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Background: Blindness (anopia) is a functional loss of vision, which could be due either to ophthalmological or neurological conditions. Blindness may be congenital or acquired. The main causes of blindness in adults are cataracts, uncorrected ametropia (myopia, astigmatism), glaucoma, macular dystrophy, cortical ischemic strokes, etc. In less than 10% of the patients, the reason for cortical blindness is bilateral occipital strokes, one of them hemorrhagic. Case Description: In the current case report, we present a 75-year-old patient with complaints of headache and visual loss. The patient h
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Khalifa, M. El, M. Mekouar, Y. Bouktib, et al. "Apoplexy of a Pituitary Macroadenoma: A Case Report." Scholars Journal of Medical Case Reports 13, no. 05 (2025): 1295–97. https://doi.org/10.36347/sjmcr.2025.v13i05.137.

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Pituitary apoplexy is an acute infarction or hemorrhage of the pituitary gland. It represents a rare mode of presentation for pituitary macroadenomas, typically non-functioning. We report a case of 65-year-old patient with a history of intracranial hypertension syndrome evolving over two years, associated with a progressive decrease in visual acuity leading to bilateral blindness. The patient presented to the emergency department with sudden-onset right hemiplegia and blindness. An emergency brain CT scan, complemented by MRI, revealed apoplexy of a pituitary macroadenoma. Given the ophthalmol
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12

Cohen, David B., and Ben J. Glasgow. "Bilateral Optic Nerve Cryptococcosis in Sudden Blindness in Patients with Acquired Immune Deficiency Syndrome." Ophthalmology 100, no. 11 (1993): 1689–94. http://dx.doi.org/10.1016/s0161-6420(93)31416-8.

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Au, Wing-Yan, Edmond S. K. Ma, Pak Chin Chow, and Yiu-Ting Kan. "Sudden blindness due to bilateral central retinal artery occlusion in a patient on eltrombopag." Annals of Hematology 93, no. 5 (2013): 881–82. http://dx.doi.org/10.1007/s00277-013-1902-2.

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DB, Cohen, and Glasgow BJ. "Bilateral Optic Nerve Cryptococcosis in Sudden Blindness in Patients with Acquired Immune Deficiency Syndrome." Journal of Neuro-Ophthalmology 14, no. 2 (1994): 125. http://dx.doi.org/10.1097/00041327-199406000-00026.

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Ayanniyi, Abdulkabir A., Uchenna Godswill Ejikeme, Yohanna Tanko, Rilwan C. Muhammad, and Obiageli E. Nnodu. "Blinding Bilateral Hyperviscosity Retinopathy in a 43-Year-Old Nigerian Male with Lymphoplasmacytic Lymphoma: A Case Report and Management Challenges." Case Reports in Oncological Medicine 2014 (2014): 1–4. http://dx.doi.org/10.1155/2014/567632.

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Lymphoplasmacytic lymphomas are rare and may present with uncommon and devastating symptoms. We report a case of a 43-year-old male who presented with bleeding gums and sudden onset of bilateral blindness but was not on anticoagulants and had no family history of bleeding disorder. He had bilateral hyperpigmented infraorbital skin lesions, visual acuities (VA) of hand motion in both eyes (blindness), round and sluggish pupils, and bilateral diffuse and extensive retinal haemorrhages obliterating the retinal details with central visual field defects. The optical coherence tomography revealed re
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16

Horai, Yoshiro, Tomoya Miyamura, Karin Shimada, et al. "Sudden onset blindness treated with pulse steroid therapy in a patient with microscopic polyangiitis." Open Medicine 6, no. 5 (2011): 631–33. http://dx.doi.org/10.2478/s11536-011-0069-2.

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AbstractWe report a 71-year-old male with microscopic polyangiitis (MPA) who developed sudden-onset, progressive, bilateral visual loss associated with a relapse of MPA symptoms. The patient was referred to our hospital, and treated with intravenous pulse steroid therapy and high-dose oral prednisolone. Although the right eye remained vision deficient, visual acuity in the left eye recovered. Ocular manifestations of MPA are quite uncommon. This case emphasizes the necessity of early detection and initiation of prompt therapy where ocular manifestations of MPA occur.
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Cullen, CL, JL Caswell, and BH Grahn. "Intravascular lymphoma presenting as bilateral panophthalmitis and retinal detachment in a dog." Journal of the American Animal Hospital Association 36, no. 4 (2000): 337–42. http://dx.doi.org/10.5326/15473317-36-4-337.

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A seven-year-old, spayed female boxer was presented for sudden blindness and red eyes of one week's duration. Ophthalmic examination revealed bilateral uveitis with complete bullous retinal detachments. Initial diagnostic testing failed to reveal evidence of systemic disease. Cytopathology of subretinal aspirates confirmed the presence of macrophages with intracytoplasmic retinal pigment, epithelial and choroidal pigment, and monocytes. Tentative diagnoses were idiopathic uveitis and retinal detachment. The dog was treated with immunosuppressive doses of prednisone. The retinas reattached and
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18

Corti, Marcelo, Rubén Solari, Diana Cangelosi, et al. "Sudden blindness due to bilateral optic neuropathy associated with cryptococcal meningitis in an AIDS patient." Revista Iberoamericana de Micología 27, no. 4 (2010): 207–9. http://dx.doi.org/10.1016/j.riam.2010.09.002.

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19

Di Zazzo, Giacomo, Isabella Guzzo, Lara De Galasso, et al. "Anterior Ischemic Optical Neuropathy in Children on Chronic Peritoneal Dialysis: Report of 7 Cases." Peritoneal Dialysis International: Journal of the International Society for Peritoneal Dialysis 35, no. 2 (2015): 135–39. http://dx.doi.org/10.3747/pdi.2013.00330.

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Background Anterior ischemic optic neuropathy (AION) is characterized by infarction of the optic nerve head due to hypoperfusion of the posterior ciliary arteries and causes sudden blindness in adults on chronic dialysis, but has rarely been described in children. Unlike adults, children do not have comorbidities related to aging. Methods We retrospectively analyzed data of 7 children on nocturnal continuous cycling peritoneal dialysis (CCPD) who developed AION identified within the Italian Registry of Pediatric Chronic Dialysis. We also summarized data from 10 cases reported in the literature
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20

Shaharudin, Abdul Hafiz, Muhamad Hafiq Ab Hamid, Rosliza Yahaya, Nik Ahmad Shaiffudin Nik Him, Nik Arif Nik Mohamed, and Azizul Fadzli Wan Jusoh. "Transient binocular blindness: A rare presentation of aortic dissection." Hong Kong Journal of Emergency Medicine 27, no. 4 (2018): 236–40. http://dx.doi.org/10.1177/1024907918816575.

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Introduction: Aortic dissection is a clinical chameleon that can have variable presenting features that require a careful history and physical examination. A non-specific presentation of this life-threatening condition causes a diagnostic dilemma among clinicians especially in the emergency department leading to grave consequences. Case Presentation: We present a case of aortic dissection that presented as an acute bilateral blindness that was associated with a sudden onset of loss of consciousness and central chest pain. Bedside carotid ultrasound showed a double lumen carotid artery suggesti
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Wang, Xun, Cong Zheng, Wen Liu, and Hui Yang. "Retinitis Pigmentosa and Bilateral Idiopathic Demyelinating Optic Neuritis in a 6-Year-Old Boy with OFD1 Gene Mutation." Case Reports in Ophthalmological Medicine 2017 (2017): 1–8. http://dx.doi.org/10.1155/2017/5310924.

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To identify the cause of a sudden binocular vision decrease in patients with retinitis pigmentosa and bilateral idiopathic demyelinating optic neuritis is difficult, but early diagnosis and treatment significantly improve the prognosis. Here, we report a 6-year-old boy with a progressive binocular vision decrease in 38 days. The patient had a history of night blindness, a mottled retina without pigmentation, extinguished electroretinographic response, tritanopia, and an absent ellipsoid zone outside the macula fovea by optical coherence tomography in both eyes. His condition was diagnosed as r
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Agarwal, Nitin, Gaurav Garg, Ajay Kumar Pal, Pranjal Dubey, Akhil Garg, and Pooja Dewan. "Sudden-Onset Bilateral Blindness in a Young Girl Receiving Parenteral Nutrition: Case Report and Review of Literature." Journal of Parenteral and Enteral Nutrition 41, no. 7 (2015): 1240–44. http://dx.doi.org/10.1177/0148607115601997.

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Mohr, Gérard, Jules Hardy, Ronald Comtois, and Hughes Beauregard. "Surgical Management of Giant Pituitary Adenomas." Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques 17, no. 1 (1990): 62–66. http://dx.doi.org/10.1017/s0317167100030055.

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ABSTRACT:During the past 25 years, 77 giant pituitary adenomas have been treated surgically, including suprasellar extensions of type C in 66 cases and of type D in 11 cases. Non-secreting adenomas were present in 53 and secreting adenomas in 24 cases. All patients except 3 presented with significant visual field defects; including bitemporal hemianopia, superior quadranopia or unilateral temporal hemianopia, contralateral blindness in 73% of the cases, and one case with sudden bilateral blindness due to acute pituitary apoplexy. A single transsphenoidal procedure was carried out in 74% of the
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Chua Jr, Ruben, Joyce Anne Regalado, and January Gelera. "Delayed Sudden Blindness From Unilateral Ophthalmic Artery Vasospasm Following Endoscopic Sinus Surgery?" Philippine Journal of Otolaryngology Head and Neck Surgery 36, no. 1 (2021): 62. http://dx.doi.org/10.32412/pjohns.v36i1.1643.

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Keywords: ophthalmic artery; vasospasm; iatrogenic; endoscopic sinus surgery; blindness
 
 Endoscopic sinus surgery (ESS) is a generally benign, minimally invasive procedure used for management of paranasal sinus diseases, although complications may occur due to proximity of vital structures such as the brain, orbit and great vessels.1 The overall ESS major complication rate is 0.5-1%, of which orbital injury accounts for 0.09% due to direct trauma.2 We report a case of unilateral delayed sudden visual loss without orbital trauma observed intraoperatively or on post[1]operative imagi
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Soysa, W. L. M., and F. G. Sivagnanam. "Posterior reversible encephalopathy syndrome as the first presentation of a connective tissue disorder: A case report." Asian Journal of Internal Medicine 2, no. 2 (2023): 72–76. http://dx.doi.org/10.4038/ajim.v2i2.91.

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Posterior Reversible Encephalopathy Syndrome (PRES) is a clinical-radiological diagnosis. Although hypertension is the main cause of this condition several secondary causes have been identified. Here we discuss a 53-year-old woman with a history of hypertension who presented with sudden onset of headache, seizures, and bilateral cortical blindness. MRI was suggestive of PRES. She had minimal blood pressure fluctuations. Antinuclear antibodies were significantly positive and a history of symmetrical polyarthritis was revealed. As the criteria for a particular connective tissue disorder were not
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Boutaj, Taha, Latifa Sbai, Hamza Lazaar, et al. "OPHTHALMOLOGIC MANIFESTATIONS REVEALING POSTERIOR REVERSIBLE ENCEPHALOPATHY SYNDROME: A CASE REPORT." International Journal of Advanced Research 12, no. 02 (2024): 657–61. http://dx.doi.org/10.21474/ijar01/18342.

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Posterior reversible encephalopathy syndrome (PRES) is a rare clinico-radiological syndrome, secondary to many diseases especially high blood pressure. First described by Hinchey in 1996, pathophysiology is not clear. Clinical manifestations are headache, seizures, altered mental state such as confusion or coma, and also visual disturbances, such as hemianopia, blurred vision, diplopia, or cortical blindness. We report the case of a Moroccan 47-years old patient who arrived at the ophthalmology emergency presenting a sudden vision loss and horizontal diplopia, associated with headache. General
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Mihalcea, Maria. "A case of Fahr’s disease in a patient treated for Parkinson’s." Romanian Journal of Psychiatry and Psychotherapy 25, no. 2 (2023): 45–47. https://doi.org/10.37897/rjpp.2023.2.2.

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Fahr’s disease (FD), also referred as familial idiopathic basal ganglia calcification (FBGC) or bilateral striopallidodentate calcinosis (BSPDC), is a rare neurodegenerative disorder characterized by bilateral calcification of the basal ganglia and other brain regions. FD typically presents with a diverse range of clinical symptoms, including neuropsychiatric manifestations, movement disorders, and various neurological features. This article presents a case of a 71-year-old woman with a complex clinical history. She initially presented with symptoms of an anxious depressive disorder, which wer
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Mihalcea, Maria. "A case of Fahr’s disease in a patient treated for Parkinson’s." Romanian Journal of Psychiatry and Psychotherapy 26, no. 4 (2024): 105–7. https://doi.org/10.37897/rjpp.2024.4.2.

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Fahr’s disease (FD), also referred to as familial idiopathic basal ganglia calcification (FBGC) or bilateral striopallidodentate calcinosis (BSPDC), is a rare neurodegenerative disorder characterized by bilateral calcification of the basal ganglia and other brain regions. FD typically presents with a diverse range of clinical symptoms, including neuropsychiatric manifestations, movement disorders, and various neurological features. This article presents a case of a 71-year-old woman with a complex clinical history. She initially presented with symptoms of an anxious depressive disorder, which
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Sundari, N., Asha Swaroop, BM Krupa, BK Madhusudhan, and S. Chaitra. "Posterior Reversible Encephalopathy Syndrome in Pregnancy." Journal of South Asian Federation of Obstetrics and Gynaecology 7, no. 3 (2015): 205–6. http://dx.doi.org/10.5005/jp-journals-10006-1358.

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ABSTRACT Posterior reversible encephalopathy syndrome (PRES) is a cliniconeuroradiological entity characterized by several symptoms of varied etiologies. The common symptoms are headache, confusion, seizures, cortical visual disturbances or blindness. Here, we report a 22 years old lady with 32 weeks of gestation who presented with complaints of acute onset of headache, sudden loss of vision with elevated blood pressure (BP), whose magnetic resonance venogram (MR venogram) revealed bilateral occipital T2 hyperintensity with restriction of diffusion suggestive of PRES. Early identification and
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Sharma, Amit Kumar, Binita Dholakia, Anita Jagetia, et al. "Posterior ischemic optic neuropathy with acute monocular vision loss following clipping of anterior communicating artery aneurysm. A case report and review of literature." Surgical Neurology International 12 (September 20, 2021): 471. http://dx.doi.org/10.25259/sni_551_2021.

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Background: The acute postoperative monocular vision loss following anterior communicating artery aneurysm clipping secondary to posterior ischemic optic neuropathy (PION) a rare presentation. Case Description: A 32-year old patient presented with a spontaneous holocranial thunderclap headache for 7 days, associated with vomiting. The SAH was diagnosed with a tiny saccular aneurysm arising from the anterior communicating artery. A left pterional craniotomy and clipping of aneurysm were done. On the 3rd postoperative day, he complained of left-sided complete blindness, and on the 5th postoperat
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Haas, L. E. M., R. S. van der Ploeg, J. J. Quak, J. P. J. Burgmans, and M. Otten. "A Young Man With Severe and Disabling Complications of Septic Shock." American Journal of Critical Care 24, no. 5 (2015): 450–52. http://dx.doi.org/10.4037/ajcc2015746.

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A young man had severe septic shock with multiorgan failure due to necrotizing fasciitis caused by group A streptococcus after endoscopic repair of a preperitoneal inguinal hernia. He was treated with surgical exploration and antibiotics and resuscitated with fluids, vasopressors, and inotropic agents. He survived this critical illness, but when he woke up from sedation, his vision was lost in both eyes. Ophthalmological evaluation revealed minimal peripapillary retinal hemorrhages without signs of papillary edema. Visually evoked potentials were negative. Magnetic resonance imaging did not sh
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Asad, Z., A. Chaudhary, and A. Awab. "ID: 64: REVERSIBLE BLINDNESS ASSOCIATED WITH DIABETIC KETOACIDOSIS: A RARE COMBINATION." Journal of Investigative Medicine 64, no. 4 (2016): 975.2–976. http://dx.doi.org/10.1136/jim-2016-000120.134.

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IntroductionA wide spectrum of ocular diseases is associated with diabetes mellitus (DM) and most of them lead to gradual loss of vision that is almost always irreversible. Sudden vision loss in severe diabetic ketoacidosis (DKA) that is reversible with treatment of the metabolic abnormality is a very rare complication that has been reported three times previously.Case PresentationA 59 year-old male with Type 1 DM presented with altered consciousness, epigastric pain, hypothermia and sudden complete bilateral vision loss for three days. He was not complaint with insulin. There was no history o
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Dietemann, Sébastien, Vincent Noblet, Alessio Imperiale, Cyrille Blondet, and Izzie Jacques Namer. "FDG PET Findings of the Brain in Sudden Blindness Caused by Bilateral Central Retinal Artery Occlusion Revealing Giant Cell Arteritis." Clinical Nuclear Medicine 40, no. 1 (2015): 45–46. http://dx.doi.org/10.1097/rlu.0000000000000598.

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Gerber, Sylvie, Christophe Orssaud, Josseline Kaplan, Catrine Johansson, and Jean-Michel Rozet. "MCAT Mutations Cause Nuclear LHON-like Optic Neuropathy." Genes 12, no. 4 (2021): 521. http://dx.doi.org/10.3390/genes12040521.

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Pathological variants in the nuclear malonyl-CoA-acyl carrier protein transacylase (MCAT) gene, which encodes a mitochondrial protein involved in fatty-acid biogenesis, have been reported in two siblings from China affected by insidious optic nerve degeneration in childhood, leading to blindness in the first decade of life. After analysing 51 families with negative molecular diagnostic tests, from a cohort of 200 families with hereditary optic neuropathy (HON), we identified two novel MCAT mutations in a female patient who presented with acute, sudden, bilateral, yet asymmetric, central visual
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Nuzzi, Raffaele, and Carlo Lavia. "Visual Field Defect after Cardiac Surgery: The Striking Role of Interdisciplinary Collaboration." Case Reports in Ophthalmological Medicine 2015 (2015): 1–5. http://dx.doi.org/10.1155/2015/904528.

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Perioperative visual loss (POVL) is a potentially devastating complication that can occur following ocular or nonocular surgery. The leading causes of this disease are retinal vascular occlusions, ischemic optic neuropathies, and cortical blindness. POVL pathogenesis is strictly influenced by surgery, anesthesia, and patients’ comorbidities. We report of a 55-year-old caucasian man who presented with complaints of sudden painless loss of vision and unilateral campimetric deficit. We recorded a preserved visual acuity but at fundus examination a bilateral ischemic optic neuropathy (ION) was sus
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Teh, Kai Xuan, Jin Hui Ho, and Hwee Ching Tee. "TRANSIENT REMISSION OF ACROMEGALY FOLLOWING PITUITARY APOPLEXY AND EARLY RELAPSE." Journal of the ASEAN Federation of Endocrine Societies 40, S1 (2025): 42. https://doi.org/10.15605/jafes.040.s1.067.

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INTRODUCTION/BACKGROUND Acromegaly is caused by excessive growth hormone (GH) secretion and secondary elevation of insulin-like growth factor-1 (IGF-1). Elevated serum IGF-1 level is a useful screening tool for acromegaly. However, IGF-1 levels may appear normal in conditions such as liver disease, malnutrition, uncontrolled diabetes mellitus and pituitary apoplexy. When serum IGF-1 levels are normal, it is easy to miss the diagnosis of acromegaly without a high index of suspicion and/or a GH suppression test. We report a case of an acromegaly patient with pituitary apoplexy and initially norm
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Sultana, Aliya, and T. Sharath Kumar. "Retinal vasculitis – Clinical manifestations and outcome at tertiary eye care centre in south India." Indian Journal of Clinical and Experimental Ophthalmology 7, no. 3 (2021): 568–73. http://dx.doi.org/10.18231/j.ijceo.2021.111.

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To study the various causes, clinical presentation, management and outcome of the retinal vasculitis cases at tertiary eye care centre. Tertiary eye care centre, Telangana State, South India. Retrospective Interventional Study. Jan 2016 to Dec 2020. Fifty one patients of retinal vasculitis presented with various clinical manifestations were examined in detail and managed. Data collected from medical records. All young patients of different age group presented with retinal vascular changes are included in the study. Patients underwent examination and laboratory workup. Few patients showed ocula
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Greene, Jacqueline J., Ilka C. Naumann, Janet M. Poulik, et al. "The Protean Neuropsychiatric and Vestibuloauditory Manifestations of Neurosarcoidosis." Audiology and Neurotology 22, no. 4-5 (2017): 205–17. http://dx.doi.org/10.1159/000481681.

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Background: A rare subset of sarcoidosis, neurosarcoidosis, is reported to occur in 5-7% of sarcoid patients and can manifest in a variety of ways. The most common are facial paralysis and optic neuritis, less commonly causing cochleovestibulopathy, blindness, anosmia, and other cranial nerve (CN) palsies. The sensory deficit may be severe and psychiatric symptoms may result from the effects of the disease or steroid treatment. Although MRI-compatible cochlear implants are now available, concerns about the feasibility of recoverable hearing with cochlear implantation in these patients as well
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Geraskinа, M. M., A. B. Galitsynа, V. A. Shuvaev, and S. S. Gosteva. "Clinical Case of Posterior Reversible Encephalopathy Syndrome in a Female Patient Undergoing Surgery for Rectal Cancer." Creative surgery and oncology 14, no. 4 (2024): 388–93. https://doi.org/10.24060/2076-3093-2024-14-4-388-393.

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Introduction. Posterior reversible encephalopathy syndrome (PRES) refers to a relatively obscure syndrome with unclear pathogenesis, leading to patient disability, occurring in 58% of cases against a background of arterial hypertension. Clinical manifestations include cephalalgia, epileptic seizures, and visual disturbances, potentially culminating in complete blindness. The clinical case represents a rare life-threatening condition that may pose challenges for an attending physician regarding the appropriate therapeutic strategy.Aim. To demonstrate the occurrence of posterior reversible encep
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40

Satria, Elan, and Fitratul Ilahi. "Juvenile Glaucoma Related to Pineal Tumor Post Ventriculoperineal Shunt Procedure: A Case Report." Bioscientia Medicina : Journal of Biomedicine and Translational Research 6, no. 14 (2022): 2614–18. http://dx.doi.org/10.37275/bsm.v6i14.656.

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Background: Glaucoma is a cause of irreversible blindness worldwide. This study aims to describe a case of juvenile open-angle glaucoma with a history of post-ventriculoperitoneal shunt perineal tumor.
 Case presentation: A 27 years old man came with complaints of blurred vision in both eyes about 2 years ago. The vision in both eyes is felt to be progressively decreasing, almost the same in both eyes. Blurred vision felt suddenly while driving 1 year ago. The patient had been diagnosed with a pineal tumor and underwent surgery to install a ventriculoperitoneal (VP) shunt for hydrocephalu
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Sanchez-Martin, J., J. Medina-Del Valle, J. Loricera, M. F. Garcia-Reija, and R. Blanco. "AB0733 CONCORDANCE BETWEEN THE 1990 ACR CLASSIFICATION CRITERIA AND THE NEW 2022 ACR/EULAR 2022 CRITERIA IN GIANT CELL ARTERITIS." Annals of the Rheumatic Diseases 82, Suppl 1 (2023): 1572.2–1573. http://dx.doi.org/10.1136/annrheumdis-2023-eular.6144.

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BackgroundClassification criteria for vasculitis, including giant cell arteritis (GCA) are under constant revision. In 2022, the American College of Rheumatology (ACR)/European League Against Rheumatism (EULAR) criteria were presented, renewing those published by ACR in 1990. They include wider range of clinical criteria and imaging tests, such as ultrasonography (US) and Positron emission tomography (PET), which has contributed to the diagnosis of a higher number of cases.ObjectivesTo assess the concordance between recent 2022 ACR/EULAR giant cell arteritis classification criteria and the cri
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42

zarei, sara, Phuong Vo, Christian Sam, Robert W. Crow, Charles Stout, and Lama Al-Khoury. "Acute Bilateral Blindness in the Setting of Sudden Onset of Bilateral Proptosis and Ophthalmoplegia: A Case Report With Literature Review." Neurology: Clinical Practice, April 14, 2021, 10.1212/CPJ.0000000000001090. http://dx.doi.org/10.1212/cpj.0000000000001090.

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ABSTRACTPurposeof review: Acute bilateral blindness has an extensive differential diagnosis that requires a careful history and physical exam to narrow down. In this paper we discuss the pathophysiology and radiographic findings of each possible diagnosis for acute bilateral blindness.Recent findings:Visual pathology with respect to bilateral blindness can be broadly broken down into three anatomic categories: media (i.e. the anterior and posterior chamber of the eye), retina, and neural visual pathway. Possible causes of rapid onset bilateral blindness include bilateral occipital infarcts, en
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Pedro-Egbe, Chinyere Nnenne, and Elizabeth Awoyesuku. "Sudden Bilateral Blindness Following Massive Uterine Bleeding: Reports of 2 Cases." March 29, 2012. https://doi.org/10.5281/zenodo.7810.

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Background: Most cases of sudden blindness are due to vascular causes. Ischemic optic neuropathy is a rare cause of blindness reported most commonly in association with collagen-vascular diseases, infectious processes, and systemic hypotension related to massive exsanguinating hemorrhage. Aim: To report 2 cases of bilateral complete visual loss following massive uterine hemorrhage. Case reports: Case 1 is a 23 year-old unmarried female student who first presented at our Eye Clinic on account of bilateral visual loss of 5 months duration. She had, had a septic abortion and profuse bleeding per
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44

Mogawer, Mohamad-Sherif, Mostafa EL-Shazly, Ayman Salah, et al. "Tacrolimus-induced posterior reversible encephalopathy syndrome presenting as left upper limb monoplegia, convulsions, and sudden blindness: case report." Egyptian Liver Journal 10, no. 1 (2020). http://dx.doi.org/10.1186/s43066-020-00064-6.

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Abstract Background To report a case of sudden onset left upper limb monoplegia, convulsions, and bilateral blindness in a patient receiving tacrolimus for immunosuppression following living donor liver transplantation (LDLT) consistent with posterior reversible encephalopathy syndrome (PRES). Case presentation We report a case of a 64-year-old male patient on tacrolimus treatment following LDLT. On day 11, during his post-operative routine follow-up. The patient developed sudden onset of left upper limb monoplegia associated with attacks of convulsions and sudden bilateral blindness. MRI reve
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Mabrouk, Amira, Besma Ben Achour, and Wassim Hmaied. "Complete blindness revealing pituitary apoplexy with recovery after transsphenoidal decompression." Acta Ophthalmologica 103, S284 (2025). https://doi.org/10.1111/aos.17155.

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Aim/Purpose: We report the case of middle aged man,who developed sudden onset of bilateral no light perception (NLP) vision after pituitary apoplexy (PA).Transsphenoidal pituitary decompression(TPPD) was performed.Three months later,the patient regained excellent functional vision in one eye but had residual visual field loss.Methods: Case report:A 37‐year‐old man,with a history of diabetes mellitus,presented to our department for acute onset of bilateral blurry vision.Ophthalmic examination was notable for bilateral NLP,sluggishly reactive pupils.Eye movements were conserved.Fundus examinatio
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Shambhu, S., and M. Vose. "High grade lymphoma in the nasopharynx presented as sudden onset of bilateral blindness." BMC Ophthalmology 4, no. 1 (2004). http://dx.doi.org/10.1186/1471-2415-4-2.

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Fideles, Rita, Marina Coelho, João Araújo, Carolina Gonçalves, Carla Henriques, and Ana Costa. "A case of optic chiasm stroke, a condition rarely described in the literature." European Journal of Case Reports in Internal Medicine, December 6, 2023. http://dx.doi.org/10.12890/2023_004213.

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Acute bilateral blindness is an emergent condition that may signal life-threatening disease. The approach focuses on identification of life-threatening disease processes, while differentiating between ocular, psychogenic and neurologic aetiologies. We present the case of an 88-year-old man with multiple cardiovascular risk factors and bilateral chronic glaucoma and cataracts. He presented to the emergency department with sudden onset bilateral loss of visual acuity with no other relevant changes on physical examination, including other neurologic deficits. Ophthalmologic observation showed no
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Shekari, Shima, Farima Farsi, Farah Ashrafzadeh, Shima Imannezhad, Ahmad Sohrab Niazi, and Samane Kamali. "Transient blindness due to mild reversible encephalopathy in a 7‐year‐old boy." Clinical Case Reports 12, no. 2 (2024). http://dx.doi.org/10.1002/ccr3.8493.

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Key Clinical MessageMild encephalopathy with a reversible splenial lesion (MERS) is a rare phenomenon, which shows transient lesion in corpus callosum and causes temporary encephalopathy features. A disturbance of consciousness and abnormal and delirious behavior are the most significant neurological symptoms. A seven‐year‐old child with a history of fever and cough was admitted to our hospital due to sudden bilateral blindness. His physical examination showed confusion, fever, and delirious behavior. No sign of meningeal irritation or focal neurological deficit was observed. The electroenceph
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Chevalley, B., M. Betello, E. Blavakis, A. Malclès, and J. Maillard. "Postoperative bilateral visual loss after a single dose of tranexamic acid." Anaesthesia Reports 13, no. 2 (2025). https://doi.org/10.1002/anr3.70020.

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SummaryA 32‐year‐old woman presented with transient visual loss following the intra‐operative administration of a single intravenous dose of tranexamic acid during urgent cholecystectomy. Apart from obesity, the patient had no notable medical history or pre‐existing ocular conditions. Immediately after surgery, the patient reported sudden onset blindness. Ophthalmological and radiologic assessments did not reveal any detectable macrovascular or organic ophthalmic lesions. The patient's vision gradually improved spontaneously, with the resolution of the dyschromatopsia on the first postoperativ
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Guerreiro, Cleo, Christine Heinrich, and Karen Walsh. "Bilateral blindness in a cat after a dental procedure, suspected to be due to segmental chorioretinal ischaemia necrosis." Journal of Feline Medicine and Surgery Open Reports 11, no. 1 (2025). https://doi.org/10.1177/20551169251313619.

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Case summary A 5-year-old female spayed domestic shorthair cat presented for sudden onset vision loss 3 days after a dental procedure. Bilateral blindness was confirmed on ocular examination, with fundoscopy revealing segmental wedge-shaped areas of retinal oedema and partial non-rhegmatogenous retinal detachments. An initial differential diagnosis included angioinvasive pulmonary carcinoma, based on previously reported fundoscopy images of this condition; however, general physical examination, blood pressure and chest radiographs were all normal. Four weeks after initial presentation, fundosc
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