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Rozprawy doktorskie na temat „Surface plasmon resonance imaging”

Autor: Grafiati
Data publikacji: 4 czerwca 2021
Data aktualizacji: 22 lutego 2025

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1

Andersson, Olof. "Imaging surface plasmon resonance." Doctoral thesis, Linköpings universitet, Sensorvetenskap och Molekylfysik, 2008. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-14923.

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The central theme of this thesis is the use of imaging Surface Plasmon Resonance (iSPR) as a tool in the characterization of surfaces with laterally varying properties. Within the scope of this work, an instrument for iSPR analysis was designed and built. SPR is a very sensitive technique for monitoring changes in optical properties in the immediate vicinity of a sensor surface, which is very useful in biosensing and surface science research. We have employed SPR in the Kretschmann configuration, wherein surface plasmons are excited by means of an evanescent field arising from total internal r
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2

Foley, Jennifer Olivia. "Design and development of surface plasmon resonance imaging microfluidic assays /." Thesis, Connect to this title online; UW restricted, 2007. http://hdl.handle.net/1773/7982.

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Beusink, J. B. "Label-free biomolecular interaction sensing on microarray using surface plasmon resonance imaging." Enschede : University of Twente [Host], 2009. http://doc.utwente.nl/60694.

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4

BELLASSAI, NOEMI. "Surface Plasmon Resonance Imaging Biosensors for Cancer Diagnosis: Detection of Circulating Tumor DNA." Doctoral thesis, Università degli studi di Catania, 2018. https://hdl.handle.net/20.500.11769/549419.

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This doctoral thesis focused on the realization of Surface Plasmon Resonance Imaging (SPRI) biosensor for the rapid, simple and label-free detection of single point mutations in the KRAS gene, standard actionable cancer biomarkers for colorectal cancer, in human plasma samples. Initially, the SPRI assay included the immobilization of specific peptide nucleic acid (PNA) probes onto the gold sensor to ensure the hybridization reaction of PNA-DNA complexes. The spatially controlled immobilization of PNA probes has been obtained by injecting PNA wild-type and PNA mutated solutions into a microflui
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5

Bellassai, Noemi. "Surface Plasmon Resonance Imaging Biosensors for Cancer Diagnosis: Detection of Circulating Tumor DNA." Doctoral thesis, Università di Catania, 2018. http://hdl.handle.net/10761/4165.

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This doctoral thesis focused on the realization of Surface Plasmon Resonance Imaging (SPRI) biosensor for the rapid, simple and label-free detection of single point mutations in the KRAS gene, standard actionable cancer biomarkers for colorectal cancer, in human plasma samples. Initially, the SPRI assay included the immobilization of specific peptide nucleic acid (PNA) probes onto the gold sensor to ensure the hybridization reaction of PNA-DNA complexes. The spatially controlled immobilization of PNA probes has been obtained by injecting PNA wild-type and PNA mutated solutions into a microflui
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6

Zhang, Jing. "High resolution solid immersion lens microscopy and its application to surface plasmon resonance imaging." Thesis, University of Nottingham, 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.431865.

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7

Aura, Angela Margherita. "Surface plasmon resonance imaging biosensors for the detection of pathogens and toxins in food." Doctoral thesis, Università di Catania, 2017. http://hdl.handle.net/10761/3746.

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The detection of pathogens and toxins in food represents an essential requirement for food quality control. Standard methods for pathogen detection rely on laborious and time-consuming growth of pathogens in different culture media followed by biochemical or serological identification. Such methods often operate with poor sensitivity and selectivity. In recent years, efforts have been made to provide rapid, reliable and sensitive detection platforms for foodborne pathogens detection. The demand for more rapid, sensitive and accurate methods has been push forward by the implementation of the Ha
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8

Aura, Angela Margherita. "Surface plasmon resonamce imaging biosensors for the detection of pathognes and toxins in food." Doctoral thesis, Università di Catania, 2017. http://hdl.handle.net/10761/3668.

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The detection of pathogens and toxins in food represents an essential requirement for food quality control. Standard methods for pathogen detection rely on laborious and time-consuming growth of pathogens in different culture media followed by biochemical or serological identification. Such methods often operate with poor sensitivity and selectivity. In recent years, efforts have been made to provide rapid, reliable and sensitive detection platforms for foodborne pathogens detection. The demand for more rapid, sensitive and accurate methods has been push forward by the implementation of the Ha
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9

Tan, Han-Min. "High resolution angle-scanning widefield surface plasmon resonance imaging and its application to bio-molecular interactions." Thesis, University of Nottingham, 2011. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.556099.

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The work described in this thesis is to develop a microscope into a high resolution bio-molecular interaction sensor. A "prism less" widefield surface plasmon microscope has been constructed and applied to imaging of interactions of protein and its antibody in aqueous media through a high NA objective. There are two main parts in this thesis: (1) design and layout of a high resolution angle scanning widefield surface plasmon resonance microscope; and (2) the application to bio-molecular interactions. In the first part, an angle-scanning widefield surface plasmon imaging (AW-SPRI) system consis
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10

Golden, Mary S. "Use of angle-resolved surface plasmon resonance imaging (SPRi) for the characterization of protein binding dynamics." Thesis, Boston University, 2012. https://hdl.handle.net/2144/31560.

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Thesis (Ph.D.)--Boston University<br>PLEASE NOTE: Boston University Libraries did not receive an Authorization To Manage form for this thesis or dissertation. It is therefore not openly accessible, though it may be available by request. If you are the author or principal advisor of this work and would like to request open access for it, please contact us at open-help@bu.edu. Thank you.<br>Protein-protein interactions are essential to multiple cellular functions. However, the individual mechanisms that control protein-protein interactions are not clearly understood, and the transient dynamics o
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11

Hook, Andrew Leslie, and andrew hook@flinders edu au. "Patterned and switchable surfaces for biomaterial applications." Flinders University. Chemistry, Physics and Earth Sciences, 2008. http://catalogue.flinders.edu.au./local/adt/public/adt-SFU20090210.161131.

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The interactions of biomolecules and cells at solid-liquid interfaces play a pivotal role in a range of biomedical applications and have hence been studied in detail. An improved understanding of these interactions results in the ability to manipulate biomolecules and concurrently cells spatially and temporally at surfaces with high precision. Spatial control can be achieved using patterned surface chemistries whilst temporal control is achieved by switchable surfaces. The combination of these two surface properties offers unprecedented control over the behaviour of biomolecules and cells at t
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12

De, Martin Eleonora. "Autoimmune hepatitis: clinical experience after liver transplantation and molecular study using surface plasmon resonance imaging-based strategy." Doctoral thesis, Università degli studi di Padova, 2015. http://hdl.handle.net/11577/3424166.

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De novo autoimmune hepatitis in patients with HCV recurrence (HCV-€R) after liver transplantation (LT) is of challenging diagnosis and the impact of autoimmune therapy (AT) is still a matter of debate. In the first part of this work the aim was to evaluate clinical, serological, histological characteristics of these patients and the impact of AT. Patients have been evaluated in two European transplant centers .Liver biopsies were retrospectively by experts pathologists. Three parameters, plasma cells infiltrate, interface hepatitis and central vein necrosis, were evaluated applying a new semi
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13

Kravets, V. V., Z. Almemar, A. V. Kotko, I. M. Dmytruk, and A. O. Pinchuk. "Fluorescent Glycine-Coated Silver Nanoparticles as Bio-Imaging Agents for the Neural Stem Cells." Thesis, Sumy State University, 2015. http://essuir.sumdu.edu.ua/handle/123456789/42509.

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We study experimentally the photoluminescence of small glycine-coated silver nanoparticles and their application as the bio-imaging markers of the neural stem cells. In addition we study nanoparticle’s toxic effects on the neural stem cells. Glycine-coated silver nanoparticles were synthesized using a thermal reduction of silver nitrate in a glycine matrix and size-separated via centrifugation. The properties of the nanoparticles were characterized using transmission electron microscopy, extinction and photoluminescence spectroscopy. Our results indicate that the nanoparticles have deleteriou
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14

Zimmerer, Cordelia. "Entwicklung eines optischen markierungsfreien Ionenkanalsensor-Arrays." Doctoral thesis, Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden, 2007. http://nbn-resolving.de/urn:nbn:de:swb:14-1193247156004-79633.

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Ligandgesteuerte Ionenkanäle sind Membranproteine, die an der Weiterleitung von Reizen und an der Kommunikation zwischen Zellen beteiligt sind. Große Bedeutung besitzt die Messung der Aktivierung der Ionenkanäle beispielsweise in der Medizin (z.B. Ionenkanalerkrankungen), der Pharmazie (z.B. Medikamenten-Screening) und in der Bionanotechnologie (z.B. molekulare Schalter). In all diesen Gebieten besteht die Forderung nach hohen Probendurchsätzen bei sehr hohem Informationsgehalt. Etablierte elektrochemische Detektionsmethoden erfüllen diese Forderung nicht. Um dieses Defizit zu überwinden, wurd
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15

Malic, Lidija. "Electro-wetting-on-dielectric digital microfluidic platform with integrated nanostructured biosensor interface for enhanced two-dimensional Surface Plasmon Resonance imaging detection." Thesis, McGill University, 2010. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=86687.

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The sensitive and specific detection of biomolecular interactions is at the heart of many routine analyses in fundamental research, medical diagnosis and environmental monitoring. In contrast to laborious and costly multiwell plate assays, recent years have witnessed a significant progress in miniaturized and integrated biosensors, such as surface plasmon resonance (SPR), tailored to these applications. While the design of various SPR biosensors has been described in literature, a robust, multichannel, low-cost and highly sensitive solution has not yet been presented. Specifically, an integrat
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16

Pendery, Joel S. "Nanoscale Patterning and Imaging of Liquid Crystals and Colloids at Surfaces." Case Western Reserve University School of Graduate Studies / OhioLINK, 2014. http://rave.ohiolink.edu/etdc/view?acc_num=case1396623443.

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17

Sereda, Alexandra. "Imagerie multi-spectrale par résonance des plasmons de surface : développement et applications." Thesis, Paris 11, 2014. http://www.theses.fr/2014PA112321/document.

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Dépistage du VIH, test de grossesse, mais également surveillance des eaux, détection de contaminants agro-alimentaires : la biodétection est au coeur des problématiques de santé actuelles. Dans ce contexte, les biocapteurs plasmoniques connaissent depuis quelques années un essor particulièrement important : de plus en plus de sociétés, telles que HORIBA Scientific, proposent des prototypes commerciaux, destinés tant à des utilisateurs du domaine de la recherche que de l'industrie. Basée sur le phénomène de résonance des plasmons de surface (communément appelé SPR) la biodétection plasmonique r
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18

Duperron, Matthieu. "Conception et caractérisation de nanoantennes plasmoniques pour la photodétection infrarouge refroidie." Thesis, Troyes, 2013. http://www.theses.fr/2013TROY0030/document.

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L’imagerie infrarouge refroidie est portée par une demande forte pour des applications dans les secteurs militaire, industriel et spatial. Les enjeux actuels de ce marché sont le fonctionnement à haute température et la fonctionnalisation spectrale des détecteurs.Ces enjeux peuvent être adressés grâce à l’utilisation de résonateurs optiques et leur faculté à concentrer le champ électromagnétique. Ce travail de thèse montre comment des résonateurs plasmoniques peuvent être intégrés dans la filière HgCdTe.La théorie temporelle des modes couplés a été utilisée, de manière analytique, pour optimis
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19

Guo, Zhen. "Insights of Taste Masking from Molecular Interactions and Microstructures of Microspheres." Thesis, University of Bradford, 2017. http://hdl.handle.net/10454/17420.

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The effects of taste masking are determined by interactions between drug and excipients as well as the microstructures of the particulate drug delivery systems (DDS). Cyclodextrin (CD) is a widely used taste masking agent, to which the relationship between kinetic parameters (Ka and Kd) of a drug and taste masking remains unexplored, which is investigated for the first time in this study. A data base of the kinetic parameters for drug-CD was established by Surface Plasmon Resonance Imaging (SPRi) and High Performance Affinity Chromatography (HPAC). Combined with the electronic tongue, Ka and K
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20

Banville, Frédéric. "Nanostructuration de surface pour l'imagerie à résonance de plasmons de surface de haute résolution." Thesis, Université Paris-Saclay (ComUE), 2019. http://www.theses.fr/2019SACLO005/document.

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En recherche pharmacologique, les cellules vivantes sont largement utilisées comme milieu d’analyse pour l’étude de phénomènes biologiques, par exemple l’apoptose et la réorganisation cellulaire. Différents outils de caractérisation sont développés pour analyser et traduire l’information biologique en information quantifiable. L’imagerie à résonance de plasmons de surface (SPR) est sensible aux variations d’indice de réfraction d’un milieu à l’interface d’une couche métallique. Elle trouve beaucoup d’applications en recherche pharmacologique, car elle permet l’acquisition d’images en temps rée
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21

Klenkar, Goran. "Protein Microarray Chips." Doctoral thesis, Linköping : Univ, 2007. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-8904.

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22

Pillet, Flavien. "Développement d'un outil d'analyse d'interactions moléculaires basé sur la résonance plasmonique de surface (SPRi)." Thesis, Toulouse, INSA, 2010. http://www.theses.fr/2010ISAT0029/document.

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Ces dernières décennies, on a assisté à l’augmentation du nombre de technologies et de concepts permettant l’analyse des interactions intermoléculaires. Dans ce contexte, les puces à fluorescence restent les plus fréquemment utilisées. Cependant, cette technologie bien que très sensible et multiplexée, ne permet pas d’avoir accès aux paramètres cinétiques, indispensables au calcul des constantes d’affinité et la recherche de systèmes alternatifs s’impose. Dans cette optique, la résonance plasmonique de surface par imagerie (SPRi) est considérée comme une véritable option. Cette technologie se
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23

Kholodtsova, Maria. "Spectral, spatial and temporal properties of multilayered epithelial tissue in vivo in presence of metal nanoparticles in multimodal spectroscopy." Thesis, Université de Lorraine, 2016. http://www.theses.fr/2016LORR0031/document.

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Le travail de thèse est consacré aux interactions spatio-, temporo- et spectro- résolue de laser avec des tissus biologiques. L'objectif de cette thèse était d'étudier l'influence des nanoparticules colloïdales embarqués dans les tissus biologiques multicouches sur leurs propriétés optiques afin de fournir plus profond et / ou plus précise de sondage. Pour ce faire, les paramètres spectroscopiques intégrales et durée de vie de fluorophore dans les environs de nanoparticules métalliques ont été analysées théoriquement et expérimentalement. L’autre partie de l'étude était de proposer de nouvelle
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24

Beltrami, Coline. "Développement d'un biocapteur plasmonique pour la détection en faibles concentrations de miARNs dans le cadre du don d'organes." Electronic Thesis or Diss., université Paris-Saclay, 2024. http://www.theses.fr/2024UPAST196.

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La surveillance des conditions physiologiques de donneurs d'organes en état de mort cérébrale est cruciale pour prévenir la dégradation des tissus. Ce suivi peut être effectué en observant la réponse inflammatoire (tempête cytokinique) à travers des biomarqueurs spécifiques : les miARNs. Ce travail propose d'utiliser l'imagerie par résonance plasmonique de surface (SPRI) pour détecter quantitativement ces miARNs. Cette recherche vise à développer un biocapteur SPRI plus sensible et spécifique pour détecter les miARNs à des concentrations inférieures à la limite de détection de ces systèmes.Tou
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25

Freixas, Angel Luis. "Surface plasmon resonance experiments." FIU Digital Commons, 2007. http://digitalcommons.fiu.edu/etd/3417.

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In this study, a Surface Plasmon Resonance (SPR) optical sensor, based on Kretschmann configuration, was designed and constructed. SPR is a useful tool for obtaining quantitative kinetic and affinity information on biomolecular interactions. The resolution and the sensitivity of our homemade SPR system was determined and optimized by using thiols and sucrose solutions. The data were normalized and processed to increase the resolution of the system. The sensograms were obtained and the kinetic constants were analyzed. The sensogram of the thiols solutions illustrated the process of associat
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Kholodtsova, Maria. "Spectral, spatial and temporal properties of multilayered epithelial tissue in vivo in presence of metal nanoparticles in multimodal spectroscopy." Electronic Thesis or Diss., Université de Lorraine, 2016. http://www.theses.fr/2016LORR0031.

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Le travail de thèse est consacré aux interactions spatio-, temporo- et spectro- résolue de laser avec des tissus biologiques. L'objectif de cette thèse était d'étudier l'influence des nanoparticules colloïdales embarqués dans les tissus biologiques multicouches sur leurs propriétés optiques afin de fournir plus profond et / ou plus précise de sondage. Pour ce faire, les paramètres spectroscopiques intégrales et durée de vie de fluorophore dans les environs de nanoparticules métalliques ont été analysées théoriquement et expérimentalement. L’autre partie de l'étude était de proposer de nouvelle
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27

Harris, Richard David. "Waveguide surface plasmon resonance biosensor." Thesis, University of Southampton, 1996. https://eprints.soton.ac.uk/398739/.

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This thesis reports the design and development of the first waveguide surface plasmon resonance (SPR) biosensor for pesticide analysis. The integrated optical format allows the fabrication of a compact sensor that may be connected to optical fibre; necessary steps towards a portable optical biosensor. A major advantage of the integrated optical approach is the possibility of fabricating multiple sensors on one substrate, and hence testing for multiple analytes in one basic assay. The SPR structure incorporates a metal film that may be employed as an electrode to study the electrochemical contr
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28

Stewart, Ciaran. "Phase differential surface plasmon imaging." Thesis, University of Exeter, 2010. http://hdl.handle.net/10036/3102.

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Surface Plasmon Resonance (SPR) has been utilised in various forms in sensors for many years. It is usually based on angular or wavelength interrogation of the reflectivity minimum found with Transverse Magnetic (TM) light. However, as the SPR is traversed there is also a very rapid change in the phase of the reflected TM light there being no such change in the Transverse Electric (TE) light. Presented in the thesis a new SPR sensor has been developed that exploits this rapid change in optical phase. Linearly polarised light of mixed TM/TE polarisation is passed through a polarization modulato
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29

Templier, Vincent. "Exploration de méthodes alternatives pour la détection de bactéries dans le sang." Thesis, Université Grenoble Alpes (ComUE), 2016. http://www.theses.fr/2016GREAS008/document.

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La présence de bactéries dans le sang, un milieu normalement stérile, peut avoir des conséquences graves voire fatales pour l’organisme atteint. Afin de diagnostiquer au plus tôt cette infection, appelée bactériémie, et ainsi administrer le traitement adéquat, il est nécessaire d’identifier les microorganismes isolés à partir du sang. Mais, la nature complexe de ce fluide biologique, associée à la faible charge bactérienne, parfois inférieure à 1 UFC par millilitre de sang ont des conséquences sur les méthodes pouvant être utilisées pour l’identification des bactéries. La plupart d’entre elles
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Pardoux, Éric. "Détection à large spectre de pathogènes bactériens à l'aide de peptides antimicrobiens." Thesis, Université Grenoble Alpes (ComUE), 2019. http://www.theses.fr/2019GREAV026/document.

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L’analyse microbiologique pour confirmer l’absence de bactéries dans des échantillons biologiques normalement sains, comme le sang, est une routine dans de nombreux laboratoires. En effet, la présence de bactéries dans le sang, appelée bactériémie, peut avoir des conséquences très graves, voire mortelles pour le patient. Le protocole standard pour la détection des bactériémies repose jusqu’ici sur l’enrichissement des échantillons sanguins prélevés sur les patients lors de l’hémoculture, afin d’obtenir une population suffisante pour analyse. La lenteur de ce procédé retarde ainsi de parfois pl
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31

Du, Yao. "Particle-modified surface plasmon resonance biosensor." Thesis, University of Cambridge, 2019. https://www.repository.cam.ac.uk/handle/1810/289388.

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Surface plasmon resonance (SPR) biosensors have attracted great attention in scientific research in the past three decades. Extensive studies on the immobilisation of biorecognition elements have been conducted in pursuit of higher sensitivity, but trialled formats have focussed on a thin layer modification next to the plasmon film, which usually requires in situ derivatization. This thesis investigates an 'off-chip' immobilisation strategy for SPR biosensing using silica particles and considers the implications of a particle-modified evanescent field on the signal amplitude and kinetics, for
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32

Nenninger, Garet Glenn. "High-resolution surface plasmon resonance biosensing /." Thesis, Connect to this title online; UW restricted, 2001. http://hdl.handle.net/1773/5840.

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33

El, kazzy Marielle. "Etude fondamentale pour l'optimisation des performances d'un nez bioélectronique basé sur des protéines liant les odorants." Electronic Thesis or Diss., Université Grenoble Alpes, 2023. http://www.theses.fr/2023GRALV105.

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La détection de molécules odorantes et de composés organiques volatils (COVs) fait l'objet d'une demande croissante dans divers domaines tels que l’industrie alimentaire, la parfumerie, le diagnostic médical, la surveillance environnementale, etc. Bien que précises et fiables, les méthodes les plus couramment employées - la chromatographie en phase gazeuse couplée à la spectrométrie de masse et les panels de nez humain ou encore des nez de chiens dressés- présentent un certain nombre d'inconvénients notamment en termes de coût et de temps. En réponse à ces contraintes, les nez électroniques (N
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34

Vukusic, Peter. "Sensing thin layers using surface plasmon resonance." Thesis, University of Exeter, 1993. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.358142.

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35

Chinowsky, Timothy Mark. "Optical multisensors based on surface plasmon resonance /." Thesis, Connect to this title online; UW restricted, 2000. http://hdl.handle.net/1773/5857.

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36

Lu, Hongbo. "Surface plasmon resonance biosensors : development and applications /." Thesis, Connect to this title online; UW restricted, 2000. http://hdl.handle.net/1773/8069.

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37

Fratzke, Scott B. "INTEGRATION OF MICROFLUIDICS WITH SURFACE PLASMON RESONANCE." DigitalCommons@CalPoly, 2010. https://digitalcommons.calpoly.edu/theses/366.

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This thesis successfully integrates laminate microfluidic devices with an analytic Surface Plasmon Resonance (SPR) instrument. Integration was accomplished at low-cost using materials such as polydimethylsiloxane (PDMS), Poly(methyl methacrylate) (PMMA), Tygon tubing, and a 3-way stopcock. The main components of this thesis are the design and fabrication of the low-cost, in-house fluidics that can integrate with upstream microfluidics and the validation of the in-house fluidics using the Biosensing Instruments BI-2000 SPR instrument. The low-cost fluidics was designed and fabricated “in-house”
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38

Prabhu, G. Radhakrishna. "Studies On Surface Plasmon Resonance And Related Experimental Methods Using Fixed Plasmon Angle." Thesis, Indian Institute of Science, 2000. https://etd.iisc.ac.in/handle/2005/205.

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Surface plasmon waves are transverse magnetic electromagnetic waves propagating along a dielectric-metal interface. These waves can be excited by resonant absorption of electromagnetic radiation leading to surface plasmon resonance (SPR) at the interface. The resonance is characterised by a reduction in the intensity of the reflected light at the interface due to strong coupling of incident optical radiation to surface plasmons. This gives rise to a minimum at a sharply defined angle of incidence, referred to as SPR angle or plasmon angle. The phenomenon of SPR has been extensively used in the
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39

Prabhu, G. Radhakrishna. "Studies On Surface Plasmon Resonance And Related Experimental Methods Using Fixed Plasmon Angle." Thesis, Indian Institute of Science, 2000. http://hdl.handle.net/2005/205.

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Surface plasmon waves are transverse magnetic electromagnetic waves propagating along a dielectric-metal interface. These waves can be excited by resonant absorption of electromagnetic radiation leading to surface plasmon resonance (SPR) at the interface. The resonance is characterised by a reduction in the intensity of the reflected light at the interface due to strong coupling of incident optical radiation to surface plasmons. This gives rise to a minimum at a sharply defined angle of incidence, referred to as SPR angle or plasmon angle. The phenomenon of SPR has been extensively used in the
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Guo, Jing. "MULTI-MODE SELF-REFERENCING SURFACE PLASMON RESONANCE SENSORS." UKnowledge, 2013. http://uknowledge.uky.edu/ece_etds/13.

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Surface-plasmon-resonance (SPR) sensors are widely used in biological, chemical, medical, and environmental sensing. This dissertation describes the design and development of dual-mode, self-referencing SPR sensors supporting two surface-plasmon modes (long- and short-range) which can differentiate surface binding interactions from bulk index changes at a single sensing location. Dual-mode SPR sensors have been optimized for surface limit of detection (LOD). In a wavelength interrogated optical setup, both surface plasmons are simultaneously excited at the same location and incident angle but
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Nehru, Neha. "Reference Compensation for Localized Surface-Plasmon Resonance Sensors." UKnowledge, 2014. http://uknowledge.uky.edu/ece_etds/41.

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Noble metal nanoparticles supporting localized surface plasmon resonances (LSPR) have been extensively investigated for label free detection of various biological and chemical interactions. When compared to other optical sensing techniques, LSPR sensors offer label-free detection of biomolecular interactions in localized sensing volume solutions. However, these sensors also suffer from a major disadvantage – LSPR sensors remain highly susceptible to interference because they respond to both solution refractive index change and non-specific binding as well as specific binding of the target anal
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Badjatya, Vaibhav. "TUNABLE LASER INTERROGATION OF SURFACE PLASMON RESONANCE SENSORS." UKnowledge, 2009. http://uknowledge.uky.edu/gradschool_theses/588.

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Surface plasmons are bound TM polarized electromagnetic waves that propagate along the interface of two materials with real dielectric constants of opposite signs. Surface plasmon resonance (SPR) sensors make use of the surface plasmon waves to detect refractive index changes occurring near this interface. For sensing purposes, this interface typically consists of a metal layer, usually gold or silver, and a liquid dielectric. SPR sensors usually measure the shift in resonance wavelength or resonance angle due to index changes adjacent to the metal layer. However this restricts the limit of de
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Green, Rebecca J. "Protein/polymer interactions investigated by surface plasmon resonance." Thesis, University of Nottingham, 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.336926.

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Berg, S. (Sonja). "Characterization and activity of surface plasmon resonance materials." Master's thesis, University of Oulu, 2017. http://urn.fi/URN:NBN:fi:oulu-201711083053.

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The goal of this study was to obtain new information about possibilities to utilize carbon dioxide (CO₂) with photocatalytic activation and reduction by using surface plasmon resonance titanium dioxide based materials decorated with platinum group metals. Carbon dioxide is known to be one of the most common greenhouse gases (GHG) and having a major impact on ongoing global warming. By utilizing CO₂ it is possible to mitigate CO₂ emissions and produce new sustainable fuels. This study included characterization of the prepared palladium (Pd) and platinum (Pt) decorated catalysts and testing thei
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"Pixel-referencing phase-sensitive surface plasmon resonance imaging sensor." 2011. http://library.cuhk.edu.hk/record=b5894708.

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Yu, Tsz Tat.<br>"December 2010."<br>Thesis (M.Phil.)--Chinese University of Hong Kong, 2011.<br>Includes bibliographical references (leaves 143-147).<br>Abstracts in English and Chinese.<br>Abstract --- p.2<br>摘要 --- p.4<br>Acknowledgements --- p.5<br>List of Figures --- p.6<br>List of Tables --- p.12<br>List of Abbreviations --- p.13<br>Table of Contents --- p.14<br>Chapter Chapter 1 --- Introduction --- p.17<br>Chapter Chapter 2 --- Literature Review<br>Chapter 2.1 --- Surface Plasmon Wave --- p.19<br>Chapter 2.2 --- Excitation of Surface Plasmon --- p.23<br>Chapter 2.3 --- Surfa
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Chen, Chi-Xian, and 陳祈先. "Investigation of Phase-Shift Interferometry Surface Plasmon Resonance Imaging System." Thesis, 2012. http://ndltd.ncl.edu.tw/handle/wnv4z2.

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碩士<br>國立虎尾科技大學<br>光電與材料科技研究所<br>100<br>The study is to conduct the phase response of the sensitivity of SPR. The researcher used nanoimprint lithography to imprint a grating and plated AU by Thermal Evaporation on the top of the grating to make a grating-coupled SPR. A cylindrical lens in an optical path can help the incident light to focus and to produce multiple incident angles. At the same plane, it can get the luminous intensity of the reflected light in different incident angle to become the intensity of the SPR image system. To detect phase changes, the researcher used a phase-shift meth
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ERMINI, MARIA LAURA. "Surface plasmon resonance imaging for the detection of single nucleotide polymorphisms." Doctoral thesis, 2013. http://hdl.handle.net/2158/794372.

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The application of the surface plasmon resonance imaging biosensor was studied for the determination of single nucleotide polymorphisms with the ultimate goal of developing a system applicable for molecular diagnostics, directly on clinical samples, such as blood. The influence of nanoparticles on SPRi system has been studied with the aim of improving the sensitivity.
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Li, Yuan. "Surface enzymatic reactions for ultrasensitive surface plasmon resonance imaging with DNA and RNA microarrays." 2006. http://www.library.wisc.edu/databases/connect/dissertations.html.

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Fang, Shiping. "Surface enzyme kinetics and enzymatically amplified biosensing of nucleic acid arrays studied by surface plasmon resonance imaging and surface plasmon fluorescence spectroscopy." 2006. http://www.library.wisc.edu/databases/connect/dissertations.html.

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Reiter, Kyle. "Analysis of Enzymatic Degradation of Cellulose Microfibrils by Quantitative Surface Plasmon Resonance Imaging." Thesis, 2012. http://hdl.handle.net/10214/4895.

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Cellulose is the most plentiful biopolymer on the planet, and as such, is a large potential energy source. Converting cellulose into ethanol first requires the disruption of the crystallinity of cellulose fibers and subsequent hydrolysis into glucose. The glucose can then be fermented, producing ethanol. The conversion of cellulose fibers to glucose is an energy intensive and costly step, which is a barrier to industrial production of cellulosic ethanol. The use of enzymes to facilitate this conversion is a promising approach. In the present study, the action of individual enzymes and combinat
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