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Artykuły w czasopismach na temat "Swine Animal Model"

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LELOVAS (Π. ΛΕΛΟΒΑΣ), P., K. MARINOU (Κ. ΜΑΡΙΝΟΥ), Th XANTHOS (Θ. ΞΑΝΘΟΣ), D. PAPADIMITRIOU (Δ. ΠΑΠΑΔΗΜΗΤΡΙΟΥ), D. PERREA (Δ. ΠΕΡΡΕΑ), and I. DONTAS (Ι. ΔΟΝΤΑ). "Swine as an animal model of cardiopulmonary resuscitation." Journal of the Hellenic Veterinary Medical Society 57, no. 1 (2017): 27. http://dx.doi.org/10.12681/jhvms.15007.

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This paper reviews the advantages of swine in relation to other animal models of cardiopulmonary resuscitation referred to in the literature. The causes of cardiac arrest and the difficulties raised during research in humans are presented. All animal models used in this particular field are discussed and a detailed review is performed regarding the major anatomical and physiological similarities between swine and man, as well as the experimental studies published in the international literature.
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Yoganandan, Narayan, Alok Shah, Jamie Baisden, et al. "Matched-pair hybrid test paradigm for behind armor blunt trauma using an experimental animal model." Trauma Surgery & Acute Care Open 9, no. 1 (2024): e001194. http://dx.doi.org/10.1136/tsaco-2023-001194.

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BackgroundThe current behind armor blunt trauma (BABT) injury criterion uses a single penetration limit of 44 mm in Roma Plastilina clay and is not specific to thoracoabdominal regions. However, different regions in the human body have different injury tolerances. This manuscript presents a matched-pair hybrid test paradigm with different experimental models and candidate metrics to develop regional human injury criteria.MethodsLive and cadaver swine were used as matched pair experimental models. An impactor simulating backface deformation profiles produced by body armor from military-relevant
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Huang, Christene A., Yasushi Fuchimoto, Zachary L. Gleit, et al. "Posttransplantation lymphoproliferative disease in miniature swine after allogeneic hematopoietic cell transplantation: similarity to human PTLD and association with a porcine gammaherpesvirus." Blood 97, no. 5 (2001): 1467–73. http://dx.doi.org/10.1182/blood.v97.5.1467.

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Posttransplantation lymphoproliferative disease (PTLD) is a major complication of current clinical transplantation regimens. The lack of a reproducible large-animal model of PTLD has limited progress in understanding the pathogenesis of and in developing therapy for this clinically important disease. This study found a high incidence of PTLD in miniature swine undergoing allogeneic hematopoietic stem cell transplantation and characterized this disease in swine. Two days before allogeneic peripheral blood stem cell transplantation, miniature swine were conditioned with thymic irradiation and in
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XANTHOS (Θ. ΞΑΝΘΟΣ), Th. "Swine model in cardiopulmonary resuscitation research." Journal of the Hellenic Veterinary Medical Society 60, no. 3 (2017): 254. http://dx.doi.org/10.12681/jhvms.14935.

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Cardiac Arrest (CA) constitutes a real medical emergency. Various experimental models have been developed in order to test experimental treatments. Animal models that have been used in CA research are rodents, rabbits, cats and dogs, primates and swine. Among these, swine are used more often. The reason behind this choice is mostly its close resemblance to the human cardiac anatomy and physiology. Various haemodynamic variables have been investigated as predictors of the return of spontaneous circulation (ROSC). Coronary Perfusion Pressure (CPP) is the only proven predictor for ROSC. CPP, whic
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Navarro-Alvarez, Nalú, Beatriz M. M. Gonçalves, Alec R. Andrews, David H. Sachs, and Christene A. Huang. "A CFA-Induced Model of Inflammatory Skin Disease in Miniature Swine." International Journal of Inflammation 2018 (June 24, 2018): 1–8. http://dx.doi.org/10.1155/2018/6916920.

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Similarities between porcine and human skin make the pig an ideal model for preclinical studies of cutaneous inflammation and wound healing. Complete Freund’s adjuvant (CFA) has been used to induce inflammation and to study inflammatory pain in several animal models. Here, we evaluated the inflammation caused by CFA injected in different layers of skin and subcutaneous (SC) tissue in a large-animal model. The degree of inflammation was evaluated at early and late time points by visual inspection and histopathologic analysis. In addition, the side effects of CFA injections were evaluated based
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Guo, Xiaomei, Bhavesh Patel, Ling Han, et al. "Novel swine model of colonic diverticulosis." American Journal of Physiology-Gastrointestinal and Liver Physiology 317, no. 1 (2019): G51—G56. http://dx.doi.org/10.1152/ajpgi.00408.2018.

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The pathophysiology of colonic diverticulosis has not been completely understood. The development of appropriate animal models is essential to study diverticular disease. To date, no large animal models are available for this disease condition. The objective of this study was to develop a swine model by damaging the colon wall, combined with or without a low-fiber diet to mimic the pathogenesis of diverticulosis. To create a weakness on the colon wall, collagenase was applied in vivo to degrade the collagen in the colon wall. Three groups of Yucatan minipigs were included. Group 1 ( n = 12) un
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KUDO, Hideyuki, Motoyuki KATAOKA, Hiroshi IRIE, et al. "Acceleration of Atherogenesis in Hyperinsulinemic Miniature Swine Animal Model." Journal of Japan Atherosclerosis Society 24, no. 10 (1997): 501–4. http://dx.doi.org/10.5551/jat1973.24.10_501.

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Zhang, Zhang, Shigeho Takarada, and Sabee Molloi. "Assessment of coronary microcirculation in a swine animal model." American Journal of Physiology-Heart and Circulatory Physiology 301, no. 2 (2011): H402—H408. http://dx.doi.org/10.1152/ajpheart.00213.2011.

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Coronary microvascular dysfunction has important prognostic implications. Several hemodynamic indexes, such as coronary flow reserve (CFR), microvascular resistance, and zero-flow pressure (Pzf), were used to establish the most reliable index to assess coronary microcirculation. Fifteen swine were instrumented with a flow probe, and a pressure wire was advanced into the distal left anterior descending artery. Adenosine was used to produce maximum hyperemia. Microspheres were used to create microvascular dysfunction. An occluder was used to produce stenosis. Blood flow from the probe (Q̇p), aor
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Misfeldt, M. L., and D. R. Grimm. "Sinclair miniature swine: an animal model of human melanoma." Veterinary Immunology and Immunopathology 43, no. 1-3 (1994): 167–75. http://dx.doi.org/10.1016/0165-2427(94)90133-3.

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Micsa, C., D. Togoe, V. A. Dutulescu, et al. "Training in laparoscopic biliary procedures in swine animal model." Journal of Biotechnology 305 (November 2019): S82. http://dx.doi.org/10.1016/j.jbiotec.2019.05.283.

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Rozprawy doktorskie na temat "Swine Animal Model"

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CHIEPPA, MARIA NOVELLA. "A NOVEL ANIMAL MODEL FOR AMYOTROPHIC LATERAL SCLEROSIS: THE SOD1G93A TRANSGENIC SWINE." Doctoral thesis, Università degli Studi di Milano, 2013. http://hdl.handle.net/2434/218986.

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Amyotrophic Lateral Sclerosis (ALS) is a fatal neurodegenerative disease that may occur in two clinically indistinguishable forms: sporadic (sALS) and familial (fALS), the latter linked to several gene mutations, mostly inheritable in a dominant fashion [Rosen et al., 1993]. The disease is characterized by selective and progressive degeneration of upper and lower motor neurons, leading to muscle weakness, atrophy and evolving to complete paralysis that results in patient death in 2 to 5 years after symptoms onset. Research on ALS has mainly relied so far on experimental rodent models carrying
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El-Beyrouthi, Nayla. "RNA interference and somatic cell nuclear transfer to generate an apolipoprotein E deficient pig : a new model of atherosclerosis." Thesis, McGill University, 2008. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=116103.

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Atherosclerosis is a complex disease which develops silently over decades and can lead to acute myocardial infarction or stroke, the main cause of death worldwide. Apoliporotein E (apo E) is a glycoprotein known for its major role in lipid metabolism and its pro-atherogenic effects. Swine make a unique and viable research model as it shares most of the anatomic and physiologic characteristics with humans, notably for the the cardiovascular system. In addition, it is the only animal species, other than nonhuman primates, that develops atherosclerosis spontaneously. In this study we examined the
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Ferreira, Guilherme José Bolzani de Campos. "Modelo experimental de acidente vascular encefálico (AVE)." Universidade de São Paulo, 2007. http://www.teses.usp.br/teses/disponiveis/10/10132/tde-24032008-141559/.

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Foi desenvolvido um modelo experimental de Acidente Vascular Encéfalo Isquêmico (AVE) em suínos utilizando seis animais jovens, oriundos de granjas da região da Grande São Paulo, com 20kg de peso vivo em média, sendo todas fêmeas e hígidas. Estes foram submetidos a sedação com Quetamina (5mg/kg), Midazolan (0,5mg/kg) e Fentanil (0,005mg/kg) por via intramuscular e posteriormente intubados via oro - traqueal. A manutenção anestésica foi realizada utilizando isoflurano (vaporizador calibrado a 1,5%). Puncionou-se uma veia auricular para fluido e medicação de emergência se necessário. Os animais
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Evans, Timothy J. "Selected aspects of the toxicokinetics of cadmium and lead in animal and cellular models /." Fulltext PDF download Free to MU Campus, others may purchase, 2002. http://wwwlib.umi.com/cr/mo/fullcit?p3074398.

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Liljenstolpe, Carolina. "Consumer valuation studies and structural modelling of the pig industry : a focus on animal welfare /." Uppsala : Dept. of Economics, Swedish University of Agricultural Sciences, 2008. http://epsilon.slu.se/200835.pdf.

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Junior, Adilson Costa Rodrigues. "Modelo animal de lavagem peritoneal contínua associada à peritoneostomia a vácuo." Universidade de São Paulo, 2015. http://www.teses.usp.br/teses/disponiveis/5/5132/tde-27102015-094052/.

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Introdução: O tratamento das peritonites difusas, apesar dos avanços alcançados, continua difícil. Diversas técnicas e protocolos vêm sendo utilizados, porém esse casos seguem com altos índices de morbidade e mortalidade . O uso de peritoneostomias foi encorajado após o surgimento da terapia a vácuo, obtendo-se resultados promissores. Porém a lavagem peritoneal contínua ainda é uma modalidade considerada tecnicamente de difícil execução e de resultados controversos. Nesse experimento desenvolvemos e propomos um novo modelo de lavagem peritoneal continua que aproveitasse a facilidade e os benef
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Jacobson, Magdalena. "Enteric diseases in pigs from weaning to slaughter /." Uppsala : Dept. of Large Animal Clinical Sciences, Swedish Univ. of Agricultural Sciences, 2003. http://epsilon.slu.se/v158.pdf.

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Witczak, Carol A. "Regulation of coronary smooth muscle intracellular Ca²⁺ levels in porcine models of hyperlipidemia, diabetic dyslipidemia, and exercise training." free to MU Campus, others may purchase, 2003. http://www.lib.umi.com/cr/mo/fullcit?p3091979.

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Freitas, Ricardo Miguel Costa de. "Desenvolvimento de um modelo experimental de crioablação vertebral em suínos guiada por tomografia computadorizada de feixe cônico." Universidade de São Paulo, 2015. http://www.teses.usp.br/teses/disponiveis/5/5151/tde-11012016-124855/.

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INTRODUÇÃO: A criocirurgia (crioablação) percutânea em tecidos ósseos próximos da medula espinhal e sistema nervoso periférico tem sido feita na prática clínica, porém sem estudos experimentais que provem sua segurança e eficácia. O objetivo deste trabalho foi desenvolver um modelo experimental suíno in vivo de crioablação vertebral guiada por tomografia computadorizada de feixe cônico (TCFC). Um estudo preliminar de morfometria da coluna vertebral suína por imagens de TCFC foi realizado. Um protocolo específico de crioablação foi criado para adaptar a bola de gelo às dimensões da vértebra suí
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Bueno, Sávia Christina Pereira. "Estudo da segurança e da estabilidade do implante de cabo-eletrodo atrial direito pela via epidemiocárdiaca através do seio transverso em modelo animal suíno." Universidade de São Paulo, 2013. http://www.teses.usp.br/teses/disponiveis/5/5156/tde-16092013-162851/.

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Introdução: Embora o implante de marcapasso atrioventricular pela via endovenosa seja considerado o estado da arte, situações clínicas e técnicas que podem impossibilitar o implante transvenoso de cabos-eletrodos têm sido cada vez mais frequentes, tornando-se necessária a proposição de abordagens cirúrgicas alternativas. Objetivos: O presente estudo visou o implante de marcapasso atrioventricular utilizando nova técnica para implante de cabo-eletrodo atrial no átrio direito, com o objetivo de avaliar no período intra-operatório e nos 30 primeiros dias de seguimento: a segurança e a reprodutibi
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Książki na temat "Swine Animal Model"

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Agriculture and Resource Management Council of Australia and New Zealand. Model code of practice for the welfare of animals: The camel. CSIRO, 1997.

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Agriculture and Resource Management Council of Australia and New Zealand. Model code of practice for the welfare of animals: Land transport of horses. CSIRO, 1998.

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Agriculture and Resource Management Council of Australia and New Zealand. Model code of practice for the welfare of animals: Land transport of pigs. CSIRO, 1997.

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Petrie, Smith Cynthia. Animal models in biomedical research: Swine. National Agricultural Library, 1993.

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Smith, Cynthia Petrie. Animal models in biomedical research: Swine. National Agricultural Library, 1991.

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Missouri--Columbia), Conference on Swine in Biomedical Research (1985 University of. Swine in biomedical research. Plenum Press, 1986.

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E, Tumbleson M., Schook Lawrence B, and International Symposium on Swine in Biomedical Research (1995 : University of Maryland), eds. Advances in swine in biomedical research. Plenum Press, 1996.

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Smith, Cynthia Petrie. Animal models in biomedical research: Poultry. National Agricultural Library, 1992.

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Tai˜wan) International Symposium on Pig Model for Biomedical Research (2e 1990 Tai˜peh. Pig model for biomedical research: Proceedings the 2nd International Symposium on Pig Model for Biomedical Research, November 29- December 2, 1990, Center of Academic Activities, Academia Sinica, Taipei, Taiwan, Republic of China. Pig Research Institute, 1992.

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Baltzell, Janet Kay. The neonatal colostrum-deprived piglet: An animal model for investigating neonatal nutrition and carnitine metabolism. 1988.

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Części książek na temat "Swine Animal Model"

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Anoop, Shivadasan. "Swine as an Animal Model in Preclinical Research." In Animal Models in Research. Springer Nature Singapore, 2024. http://dx.doi.org/10.1007/978-981-97-0048-6_18.

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Sun, Albert Y., M. E. Tumbleson, James O. Dexter, and Grace Y. Sun. "Miniature Swine as an Animal Model for Alcohol Research." In Molecular Mechanisms of Alcohol. Humana Press, 1989. http://dx.doi.org/10.1007/978-1-4612-4514-8_27.

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Donald, V. Cramer, G. Podesta Luis, and Makowka Leonard. "Kidney Transplantation in Yucatan Miniature Swine." In Handbook of Animal Models in Transplantation Research. CRC Press, 2024. http://dx.doi.org/10.1201/9781003574156-4.

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Hampshire, Victoria, John Bacher, Melvin Dennis, Axel Wolff, and Melissa Yarko. "Early Characterization of Panepinto Micro/Miniature Swine for Use as Transgenic Animal Models." In Advances in Swine in Biomedical Research. Springer US, 1996. http://dx.doi.org/10.1007/978-1-4615-5885-9_23.

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Schueda, Marco Antonio, Thiago Fuchs, Welington Martins Belo, Lara Thaís Marcon, Leide Daiana Bay, and Fernanda Heidemann. "Animal model for bone implant in swine." In UNITING KNOWLEDGE INTEGRATED SCIENTIFIC RESEARCH FOR GLOBAL DEVELOPMENT. Seven Editora, 2023. http://dx.doi.org/10.56238/uniknowindevolp-136.

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Objective: The main purpose of this study was to develop an Animal Model that could accommodate evaluation experiments for cortico-spongy implants in the areas of orthopedics, dentistry, and neurology. Methodology: On the anteromedial surface of the proximal third of the tibia of pigs, we have a cortico-spongy area that is basically subcutaneous. This region proved to be ideal for this purpose. Results and discussions: The pig is already a well-known animal for testing biomaterials in bones because its bone regeneration rate (1.2 and 1.5 mm/d) is comparable to that of humans (1.0 and 1.5 mm/d)
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Schueda, Marco Antonio, Thiago Fuchs, and Lara Thaís Marcon. "Minimally invasive animal model for bone implant in swine." In UNITING KNOWLEDGE INTEGRATED SCIENTIFIC RESEARCH FOR GLOBAL DEVELOPMENT. Seven Editora, 2023. http://dx.doi.org/10.56238/uniknowindevolp-073.

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Objective: The present study aimed to develop a minimally invasive animal model that could accommodate evaluation experiments for cortico-spongy implants in the areas of orthopedics, dentistry, and neurology. Methodology: On the anteromedial surface of the proximal third of the tibia of pigs, we have a cortico-spongy area that is basically subcutaneous. This region proved to be ideal for this purpose. Results and discussions: The pig is already a well-known animal for testing biomaterials in bones because its bone regeneration rate (1.2 and 1.5 mm/d) is comparable to that of humans (1.0 and 1.
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de Vos, C. J., H. W. Saatkamp, and R. B. M. Huirne. "Impact of preventive measures on the probability of classical swine fever virus introduction in regions of the European Union: a model study." In Book of Abstracts of the 52nd Annual Meeting of the European Association for Animal Production. Brill | Wageningen Academic, 2001. https://doi.org/10.1163/9789004683648_354.

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I. Khalafalla, Abdelmalik, and Yahia H. Ali. "Rabies Virus Infection in Livestock." In Veterinary Medicine and Science. IntechOpen, 2021. http://dx.doi.org/10.5772/intechopen.98228.

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Rabies is a lethal zoonotic encephalomyelitis and a major challenge to public and animal health. Livestock are affected by rabies mostly through bites of rapid dogs or wildlife carnivore\'s species. They are considered as ‘dead-end’ hosts that do not transmit the virus. Rabies in livestock has been endemic in many developing countries for many years and diagnosed through clinical signs and dog-biting history. An introduction on rabies situation in farm animals will be given then subchapters including `rabies in bovines, rabies in small ruminants, rabies in swine and rabies in camelids. In each
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Vu Thuy Hong Loan, Nguyen, Ho Trung Thong, Le Nu Anh Thu, and Ho Viet Duc. "Acidifiers as Alternatives for Antibiotics Reduction and Gut Health Improvement for Poultry and Swine." In Veterinary Medicine and Science. IntechOpen, 2023. http://dx.doi.org/10.5772/intechopen.112963.

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Using antibiotics of low doses as feed additives could support to improve poultry and swine performances. However, these applications have caused resistance of bacteria and antibiotic residues in foods of animal origins. Therefore, efforts were focused on solutions to replace antibiotics as growth promoters (AGPs). There are many alternatives for AGPs, in which organic acids are one of the important alternatives. The aim of this chapter is to review publications on these acids and their other forms namely as acidifiers using as feed additives including their names and forms, mode of actions, s
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Redel, Bethany K., Paula R. Chen, Bhanu Telugu, et al. "Accelerating genomic improvement in pigs by using reproductive biotechnologies." In Burleigh Dodds Series in Agricultural Science. Burleigh Dodds Science Publishing Limited, 2025. https://doi.org/10.19103/as.2024.0137.16.

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To meet the food demand of the growing population, there's a need to increase the amount of protein produced from animals. Pork is the second largest contributor of global meat consumption. Identifying ways to increase the efficiency of pig production is pivotal to meeting the US and global demand for nutrients and maintaining resilient supply chains. Genome editing technology can accelerate genetic improvements by introgressing novel traits, decreasing the number of generations required to incorporate the desired allele(s), providing solutions to animal welfare concerns, maximizing nutrient y
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Streszczenia konferencji na temat "Swine Animal Model"

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Bayraktar, E., J. Cortese, J. Ognard, et al. "E-033 Cerebrospinal fluid-venous leak embolization in swine: a novel animal model." In SNIS 22nd Annual Meeting Abstracts. BMJ Publishing Group Ltd., 2025. https://doi.org/10.1136/jnis-2025-snis.149.

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Zeng, Zijing, David F. Kallmes, Yong Hong Ding, et al. "Hemodynamics of Elastase-Induced Aneurysms in Rabbit: A New High Flow Bifurcation Model." In ASME 2011 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2011. http://dx.doi.org/10.1115/sbc2011-53819.

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An intracranial aneurysm (IA) is a pathological condition of cerebral arteries characterized by local enlargements of the arterial wall, typically into a saccular shape. Rupture of the aneurysm sac can result in devastating cerebral hemorrhage. Hemodynamic factors are believed to play an important role in initiation, development and rupture of IAs [1–3]. However, the coupling between hemodynamics and aneurysm pathophysiology is complex and remains poorly understood. Patient specific diagnostics regarding risk of rupture can be substantially advanced by improving our understanding of the in-viv
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Alexander, A. Yohan, Esref A. Bayraktar, Yasuhito Ueki, et al. "Feasibility of a Swine-Based Animal Model for Endoscopic Skull Base Surgery and Reconstruction: An Ex-Vivo and Live Animal Study." In 33rd Annual Meeting North American Skull Base Society. Georg Thieme Verlag KG, 2024. http://dx.doi.org/10.1055/s-0044-1780371.

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Setlur Nagesh, Swetadri Vasan, Emily Vanderbilt, Carmon Koenigsknecht, et al. "First in-vivo demonstration of 1000fps High Speed Coronary Angiography (HSCA) in a swine animal model." In Clinical and Biomedical Imaging, edited by Barjor S. Gimi and Andrzej Krol. SPIE, 2024. http://dx.doi.org/10.1117/12.3006858.

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Schinstock, Emma, Michael Bielecki, D’Anne Kudlik, Michael Eggen, and Paul A. Iaizzo. "Development of a Dilated Cardiomyopathy Heart Failure Model Employing High-Rate Pacing via an Implantable Leadless Pacemaker: Utilized for in Situ and Ex Vivo Investigations." In 2022 Design of Medical Devices Conference. American Society of Mechanical Engineers, 2022. http://dx.doi.org/10.1115/dmd2022-1064.

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Abstract Isolated heart failure models are valuable to researchers for multiple uses, including device design. Currently, models often use artificial materials and/or simulated pulsatile pre-clinical models or alternatively, employ animal models which often present obstacles to gaining access to the heart. The Visible Heart® apparatus allows researchers to benefit from a live tissue model while increasing access to the heart and adding the abilities to directly visualize the anatomic effects of a therapy or device. This work presents the development of a model to mimic dilated cardiomyopathy i
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Chieh Chen, Yu, Li Yun Wang, Chi Chih Chen, et al. "CD154 ELEVATING CELLULAR IMMUNITY BY UP-REGULATING THE PERCENTAGES OF ANTIGEN-SPECIFIC POSITIVE INTERFERON-GAMMA EXPRESSING CELLS." In Singapore International Conference on Research in Life-Science & Healthcare, 04-05 March 2025. Global Research & Development Services Publishing, 2025. https://doi.org/10.20319/icrlsh.2025.12.

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CD154 plays a central role in the development and regulation of adaptive immune responses in mammals and thus may act as a potential molecular adjuvant due to its enhancement of cytokine expression in immune cells. In this study, CD154-coding sequence was linked with the E2 antigen sequence of the Classical swine fever virus (CSFV) to produce an E2-CD154 vaccine and the specific pathogen free piglets at the age of 4-week old was used as an animal model. The CpG adjuvant, a Toll-like receptor 9 agonist, was used as a positive control. The animals were randomized into three groups and primarily
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Kipen, V. N., and E. V. Snytkov. "BIONFORMATIC ANALYSIS OF THE GENOMES OF WILD AND DOMESTIC ANIMALS OF THE SPECIES SUS SCROFA TO UPGRADE THE “SWINE/WILD BOAR” DIFFERENTIATION MODEL." In OpenBio-2023. ИПЦ НГУ, 2023. http://dx.doi.org/10.25205/978-5-4437-1526-1-6.

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Using bioinformatic methods, the analysis of projects on genome-wide sequencing (NGS) of animals of the species Sus scrofa scrofa (wild boar) and Sus scrofa domesticus (domestic pig) was carried out, as a result of which polymorphisms (SNPs) with significant differentiating potential were determined.
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Seipel, Justin E. "Analytic-Holistic Two-Segment Model of Quadruped Back-Bending in the Sagittal Plane." In ASME 2011 International Design Engineering Technical Conferences and Computers and Information in Engineering Conference. ASMEDC, 2011. http://dx.doi.org/10.1115/detc2011-48853.

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Back-bending in the sagittal plane is common in many animals during legged locomotion and could be useful for robots. However, to our knowledge, there exists no analytical mechanistic model of sagittal-plane back bending legged locomotion of quadrupeds. Such a mechanistic model and knowledge derived from it is expected to enable direct analysis and insight into back bending locomotion and can be applied to the study of biomechanics or the design of robots. Here a whole-body mechanistic model is developed and governing equations of motion are derived to provide insight into the mathematical str
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Zhingre Sanchez, Jorge D., Emma A. Schinstock, Michael G. Bateman, and Paul A. Iaizzo. "The Development and Testing of a Fixation Apparatus for Inducing the Coaptation of the Cardiac Atrioventricular Valves." In 2019 Design of Medical Devices Conference. American Society of Mechanical Engineers, 2019. http://dx.doi.org/10.1115/dmd2019-3298.

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As the prevalence of mitral and tricuspid valvular disease continues to grow with the aging population [1,2], there is a growing critical need to treat high mortality risk patients using minimally invasive and/or non-surgical percutaneous procedures. However, these transcatheter procedures, especially those aimed at repairing or replacing the mitral and tricuspid valves, are mostly still in development and/or early clinical testing. Catheter delivery, prosthesis fixation, and/or demonstrating device efficacy are major challenges currently being addressed [3,4]. Although in situ animal models c
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Badimon, L., J. J. Badimon, and V. Fuster. "ACUTE THROMBOSIS IN STENOTIC AREAS: IMPORTANCE OF THE VASCULAR MATRIX EXPOSED TO BLOOD." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1642842.

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The platelet response to angioplasty or spontaneous plaque rupture leads to acute thrombotic occlusion under certain conditions. We analyzed the role of local shear rate (flow and vessel cross-section related), the nature of the exposed matrix and the effect of thrombin inhibition in platelet acute response to injury. Collagen type I (exposed in plaque rupture) and de-endothelialized pig aorta (mild injury) were exposed to pig blood in a tubular perfusion chamber with well characterized flow conditions, placed within an extracorporeal circuit in swine (N=20). Platelet deposition was measured b
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Raporty organizacyjne na temat "Swine Animal Model"

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Robinson, Jaimie S. Yucatan Miniature Swine as an Animal Model for Dengue-1 Disease. Defense Technical Information Center, 2005. http://dx.doi.org/10.21236/ad1014518.

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Lairet, Julio. Establishment of a Clinically Relevant Blunt Injury Animal Model for Extremity Compartment Syndrome in the Adult Swine (Sus scrofa). Defense Technical Information Center, 2011. http://dx.doi.org/10.21236/ada562286.

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Lahav, Ori, Albert Heber, and David Broday. Elimination of emissions of ammonia and hydrogen sulfide from confined animal and feeding operations (CAFO) using an adsorption/liquid-redox process with biological regeneration. United States Department of Agriculture, 2008. http://dx.doi.org/10.32747/2008.7695589.bard.

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The project was originally aimed at investigating and developing new efficient methods for cost effective removal of ammonia (NH₃) and hydrogen sulfide (H₂S) from Concentrated Animal Feeding Operations (CAFO), in particular broiler and laying houses (NH₃) and hog houses (H₂S). In both cases, the principal idea was to design and operate a dedicated air collection system that would be used for the treatment of the gases, and that would work independently from the general ventilation system. The advantages envisaged: (1) if collected at a point close to the source of generation, pollutants would
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