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Artykuły w czasopismach na temat „Symbiose intestinale”

Autor: Grafiati

Data publikacji: 30 listopada 2024

Data aktualizacji: 31 lipca 2025

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1

Bayer, Wolfgang, and Karlheiz Schmidt. "Intestinale Dysbiosen erkennen und therapieren." Ernährung & Medizin 32, no. 03 (2017): 105–8. http://dx.doi.org/10.1055/s-0043-116347.

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ZusammenfassungEine Dysbiose bezeichnet im Gegensatz zur Eubiose, Normobiose oder Symbiose Veränderungen der intestinalen Mikrobiota (früher als Darmflora bezeichnet), die mit krankhaften, häufig entzündlichen Symptomen korreliert ist. Ursachen einer Dysbiose sind z. B. eine Überwucherung mit pathogenen Keimen, chronisch entzündliche Darmerkrankungen, aber auch Einflüsse durch Arzneimittel wie Antibiotika, Kortikosteroide etc. Vielfältige weitere Wechselwirkungen sind zu berücksichtigen wie Ernährungseinflüsse, Genussgifte (Rauchen, Alkohol) sowie auch Wechselwirkungen mit dem Hormonsystem, de

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Koga, Ryuichi, Masahiko Tanahashi, Naruo Nikoh, et al. "Host’s guardian protein counters degenerative symbiont evolution." Proceedings of the National Academy of Sciences 118, no. 25 (2021): e2103957118. http://dx.doi.org/10.1073/pnas.2103957118.

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Microbial symbioses significantly contribute to diverse organisms, where long-lasting associations tend to result in symbiont genome erosion, uncultivability, extinction, and replacement. How such inherently deteriorating symbiosis can be harnessed to stable partnership is of general evolutionary interest. Here, we report the discovery of a host protein essential for sustaining symbiosis. Plataspid stinkbugs obligatorily host an uncultivable and genome-reduced gut symbiont, Ishikawaella. Upon oviposition, females deposit “capsules” for symbiont delivery to offspring. Within the capsules, the f

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Ohbayashi, Tsubasa, Kazutaka Takeshita, Wataru Kitagawa, et al. "Insect’s intestinal organ for symbiont sorting." Proceedings of the National Academy of Sciences 112, no. 37 (2015): E5179—E5188. http://dx.doi.org/10.1073/pnas.1511454112.

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Symbiosis has significantly contributed to organismal adaptation and diversification. For establishment and maintenance of such host–symbiont associations, host organisms must have evolved mechanisms for selective incorporation, accommodation, and maintenance of their specific microbial partners. Here we report the discovery of a previously unrecognized type of animal organ for symbiont sorting. In the bean bug Riptortus pedestris, the posterior midgut is morphologically differentiated for harboring specific symbiotic bacteria of a beneficial nature. The sorting organ lies in the middle of the

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4

Tan, Tze Guan, Esen Sefik, Naama Geva-Zatorsky, et al. "Identifying species of symbiont bacteria from the human gut that, alone, can induce intestinal Th17 cells in mice." Proceedings of the National Academy of Sciences 113, no. 50 (2016): E8141—E8150. http://dx.doi.org/10.1073/pnas.1617460113.

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Th17 cells accrue in the intestine in response to particular microbes. In rodents, segmented filamentous bacteria (SFB) induce intestinal Th17 cells, but analogously functioning microbes in humans remain undefined. Here, we identified human symbiont bacterial species, in particularBifidobacterium adolescentis, that could, alone, induce Th17 cells in the murine intestine. Similar to SFB,B. adolescentiswas closely associated with the gut epithelium and engendered cognate Th17 cells without attendant inflammation. However,B. adolescentiselicited a transcriptional program clearly distinct from tha

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Vermehren, Cláudia Almeida Alves, and Tayna Ofelia Freitas Suarez. "Symbiosis in the microbiome of people with asd and its effects on the brain-intestine linkage." Research, Society and Development 11, no. 17 (2022): e49111736735. http://dx.doi.org/10.33448/rsd-v11i17.36735.

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Researches show that individuals with Autistic Spectrum Disorder (ASD), present an imbalance in the intestinal microbiota, by the study carried out, there is a possibility of mitigating the characteristic symptoms of Autistic Spectrum Disorder, through the symbiosis in the intestinal microbiome. The objective of this bibliographic review is to analyze the influence of symbiosis on the microbiome in the intestine-brain axis in individuals with ASD and to verify the nutritional needs of this individual, in order to support nutritional strategies. Analyzing the gut-brain axis of children with ASD

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6

Takahashi, Kyoko, Yutaka Sugi, Kou Nakano, et al. "Epigenetic Control of the Host Gene by Commensal Bacteria in Large Intestinal Epithelial Cells." Journal of Biological Chemistry 286, no. 41 (2011): 35755–62. http://dx.doi.org/10.1074/jbc.m111.271007.

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Intestinal epithelial cells (IECs) are continuously exposed to large numbers of commensal bacteria but are relatively insensitive to them, thereby averting an excessive inflammatory reaction. We have previously reported that the hyporesponsiveness of a human IEC line to LPS was primarily the result of a down-regulation of TLR4 gene transcription through epigenetic mechanisms. In the present study we show that DNA methylation in the 5′ region of the TLR4 gene is significantly higher in IECs than in splenic cells in vivo. The methylation was shown to be dependent on the differentiation state of

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7

Kolopp-Sarda, Marie-Nathalie. "Système immunitaire muqueux et microbiote intestinal : Histoire d’une symbiose." Revue Francophone des Laboratoires 2016, no. 484 (2016): 39–47. http://dx.doi.org/10.1016/s1773-035x(16)30222-2.

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Franke, Maximilian, Benedikt Geier, Jörg U. Hammel, Nicole Dubilier, and Nikolaus Leisch. "Coming together—symbiont acquisition and early development in deep-sea bathymodioline mussels." Proceedings of the Royal Society B: Biological Sciences 288, no. 1957 (2021): 20211044. http://dx.doi.org/10.1098/rspb.2021.1044.

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How and when symbionts are acquired by their animal hosts has a profound impact on the ecology and evolution of the symbiosis. Understanding symbiont acquisition is particularly challenging in deep-sea organisms because early life stages are so rarely found. Here, we collected early developmental stages of three deep-sea bathymodioline species from different habitats to identify when these acquire their symbionts and how their body plan adapts to a symbiotic lifestyle. These mussels gain their nutrition from chemosynthetic bacteria, allowing them to thrive at deep-sea vents and seeps worldwide

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9

Hagymási, Krisztina, Anna Bacsárdi, Anna Egresi, Evelin Berta, Zsolt Tulassay, and Gabriella Lengyel. "A bélflóra patofiziológai jelentősége és szerepe mint terápiás célpont májbetegségekben." Orvosi Hetilap 159, no. 36 (2018): 1465–74. http://dx.doi.org/10.1556/650.2018.31178.

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Abstract: The community of microorganisms in the intestine, namely gut microbiome lives in symbiosis with the host, contributing to its homeostasis and influencing it simultaneously. It can be suspected that gut microbiome plays a central role in the pathophysiology of intestinal and extraintestinal diseases: determining their development, progress and complications. Recently, intestinal microbiome has become a highlighted field of interest and important topic in research, especially in hepatology. It is in the focus of relevant research as the liver is the organ which meets nutrients, bacteri

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10

Lindner, Cornelia, Benjamin Wahl, Lisa Föhse, et al. "Age, microbiota, and T cells shape diverse individual IgA repertoires in the intestine." Journal of Experimental Medicine 209, no. 2 (2012): 365–77. http://dx.doi.org/10.1084/jem.20111980.

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Intestinal immunoglobulin A (IgA) ensures host defense and symbiosis with our commensal microbiota. Yet previous studies hint at a surprisingly low diversity of intestinal IgA, and it is unknown to what extent the diverse Ig arsenal generated by somatic recombination and diversification is actually used. In this study, we analyze more than one million mouse IgA sequences to describe the shaping of the intestinal IgA repertoire, its determinants, and stability over time. We show that expanded and infrequent clones combine to form highly diverse polyclonal IgA repertoires with very little overla

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11

Ciche, Todd A., Kwi-suk Kim, Bettina Kaufmann-Daszczuk, Ken C. Q. Nguyen, and David H. Hall. "Cell Invasion and Matricide during Photorhabdus luminescens Transmission by Heterorhabditis bacteriophora Nematodes." Applied and Environmental Microbiology 74, no. 8 (2008): 2275–87. http://dx.doi.org/10.1128/aem.02646-07.

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ABSTRACT Many animals and plants have symbiotic relationships with beneficial bacteria. Experimentally tractable models are necessary to understand the processes involved in the selective transmission of symbiotic bacteria. One such model is the transmission of the insect-pathogenic bacterial symbionts Photorhabdus spp. by Heterorhabditis bacteriophora infective juvenile (IJ)-stage nematodes. By observing egg-laying behavior and IJ development, it was determined that IJs develop exclusively via intrauterine hatching and matricide (i.e., endotokia matricida). By transiently exposing nematodes t

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12

Pédron, Thierry, Giulia Nigro, and Philippe J. Sansonetti. "From homeostasis to pathology: decrypting microbe–host symbiotic signals in the intestinal crypt." Philosophical Transactions of the Royal Society B: Biological Sciences 371, no. 1707 (2016): 20150500. http://dx.doi.org/10.1098/rstb.2015.0500.

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Metagenomic analysis of the human intestinal microbiome has provided a wealth of information that allowed an exceptionally detailed description of its microbial content and physiological potential. It also set the basis for studies allowing correlation of alterations in the balance of this microbiota and the occurrence of a certain number of emerging diseases, such as inflammatory bowel diseases, obesity and diabetes, and possibly colorectal cancer. The time has come to give the intestinal microbiota in symbiosis with its host an experimental dimension. This brief review summarizes our attempt

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13

Bukharin, O. V., E. V. Ivanova, N. B. Perunova, and I. A. Nikiforov. "FUNCTIONAL GROUPS OF BIFIDOFLORA OF INTESTINAL MICROBIOTA IN ASSOCIATIVE SYMBIOSIS OF HUMAN." Journal of microbiology epidemiology immunobiology, no. 1 (February 28, 2018): 3–9. http://dx.doi.org/10.36233/0372-9311-2018-1-3-9.

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Aim. Aim of the research is the identification of functional groups of human gut bifidoflora based on analysis of the spectrum of metabolites features, proteome, bioprofile, immunoregulatory properties and the ability to differentiate «self/non-self» among the associative microbiota. Materials and methods. The materials are 260 strains ofbifidobacteria isolated from 122 intestinal microsymbiocenoses. Experimental studies were carried out using bacteriological, chromatographic and immunological methods. Statistical processing of material is carried out by means of the package Statistica 10.0 us

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14

Dudun, Andrei A., Dariana V. Chesnokova, Vera V. Voinova, Anton P. Bonartsev, and Garina A. Bonartseva. "Changes in the Gut Microbiota Composition during Implantation of Composite Scaffolds Based on Poly(3-hydroxybutyrate) and Alginate on the Large-Intestine Wall." Polymers 15, no. 17 (2023): 3649. http://dx.doi.org/10.3390/polym15173649.

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The development of biopolymer scaffolds for intestine regeneration is one of the most actively developing areas in tissue engineering. However, intestinal regenerative processes after scaffold implantation depend on the activity of the intestinal microbial community that is in close symbiosis with intestinal epithelial cells. In this work, we study the impact of different scaffolds based on biocompatible poly(3-hydroxybutyrate) (PHB) and alginate (ALG) as well as PHB/ALG scaffolds seeded with probiotic bacteria on the composition of gut microbiota of Wistar rats. Implantation of PHB/ALG scaffo

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15

Bobyr, V. V., L. O. Stechenko, V. P. Shirobokov, O. A. Nazarchuk, and O. V. Rymsha. "The role of sorbents and probiotics in prevention of structural and morphological disorders in the small intestine of animals developing in dysbiosis." Reports of Morphology 26, no. 2 (2020): 45–50. http://dx.doi.org/10.31393/morphology-journal-2020-26(2)-07.

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The past decade is characterized by a noticeable increase in the interest of physicians in all areas of activity in the development of new and improvement of existing approaches to the correction of dysbiotic disorders. Among them, the concept of using probiotics occupies a leading position. At the same time, some enterosorbents, the mechanism of action of which is largely due to the sanitation of the intestinal lumen and due to this improvement of conditions for the vital activity of the physiological microbiota, can be attributed to the group of means of improving the normal microflora. In t

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Aytbaev, K. A., I. T. Murkamilov, and R. R. Kaliev. "Chronic kidney disease: pathophysiological role of dysbiosis of intestine and renoprotective effectiveness of interventions concerning its modulation." Medical Journal of the Russian Federation 22, no. 3 (2016): 157–62. http://dx.doi.org/10.18821/0869-2106-2016-22-4-157-162.

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The review presents data concerning disorders of quantitative and qualitative content of intestinal microbiota in patients with chronic kidney disease. The causes enhancing development of intestinal dysbiosis and sub-clinical inflammation under chronic disease of kidneys are considered. The results of preliminary studies concerning investigation of particular approaches to therapy of chronic kidney disease directed to restoring of intestinal symbiosis and neutralization of bacterial endotoxins and adsorption of uremic toxins of intestinal origin are presented.

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Mayatskaya, T. A., L. A. Kharitonova, O. V. Papysheva, and A. M. Zatevalov. "Formation of intestinal microbiocenosis in children born to mothers with gestational diabetes mellitus." Experimental and Clinical Gastroenterology 1, no. 1 (2021): 96–105. http://dx.doi.org/10.31146/1682-8658-ecg-185-1-96-105.

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Rationale. The global medical community currently studies the influence of microbiocenosis on macroorganism. The metabolome of the human gut microbiome may be a factor in the development of pathology in tissues and organs.Objective. To improve the early diagnosis of intestinal microecology disorders in infants by determining the species composition and functional activity of the intestinal microflora to predict the health status of children born to mothers with diabetes.Materials and methods. We studied the intestinal microbiocenosis in 60 infants aged 1–28 days, including 22 infants by health

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18

Mazmanian, Sarkis K., June L. Round, and Dennis L. Kasper. "A microbial symbiosis factor prevents intestinal inflammatory disease." Nature 453, no. 7195 (2008): 620–25. http://dx.doi.org/10.1038/nature07008.

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Anhê, Fernando F., Nicole G. Barra, and Jonathan D. Schertzer. "Glucose alters the symbiotic relationships between gut microbiota and host physiology." American Journal of Physiology-Endocrinology and Metabolism 318, no. 2 (2020): E111—E116. http://dx.doi.org/10.1152/ajpendo.00485.2019.

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Bacteria and mammals exhibit all aspects of symbiosis. Metabolic flux in bacteria and in specific host cells can influence host-microbe symbiotic relationships and tip the balance between mutualism, commensalism, and parasitism. The relationship between microbes and host metabolism is bidirectional: microbes can influence host blood glucose, but glucose levels can influence the microbiota and host response to specific bacteria. A key consideration determining symbiotic relationships is compartmentalization of bacterial niches by mucosal, chemical, and physical barriers of the gut. We propose t

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Yunker, Rebecca, Geon Goo Han, Hien Luong, and Shipra Vaishnava. "Intestinal Epithelial Cell Intrinsic Zinc Homeostasis is Critical for Host-Microbiome Symbiosis." Journal of Immunology 210, no. 1_Supplement (2023): 82.18. http://dx.doi.org/10.4049/jimmunol.210.supp.82.18.

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Abstract A robust intestinal barrier is essential for maintaining host-microbiome symbiosis. Defects in the intestinal barrier are associated with a broad range of inflammatory and metabolic diseases. Pharmacological doses of Zinc (Zn) are widely used to improve intestinal barrier function; however, the precise cellular role of Zn in regulating the intestinal barrier during health and disease is not known. A better understanding of how Zn regulates the gut barrier and intestinal epithelial cells (IEC) could enable the development of targeted Zn-based therapeutic approaches. To understand the i

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Gebhart, C. J., S. McOrist, G. H. K. Lawson, J. E. Collins, and G. E. Ward. "Specific in situ Hybridization of the Intracellular Organism of Porcine Proliferative Enteropathy." Veterinary Pathology 31, no. 4 (1994): 462–67. http://dx.doi.org/10.1177/030098589403100409.

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The identity of the intracellular bacteria found in the enterocytes of pigs with proliferative enteropathy was investigated using specific DNA probes to various Campylobacter species and to a novel organism, ileal symbiont intracellularis. The ilea from pigs (Nos. 1–7) that were diagnosed by routine histopathology as having proliferative enteropathy were used. Diagnosis was made on the basis of proliferation of the enterocytes on hematoxylin and cosin-stained sections and the presence of large numbers of intracellular curved organisms on Warthin-Starry silver-stained sections. Four of these pi

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Wang, Shuai, Qianhong Ye, Xiangfang Zeng, and Shiyan Qiao. "Functions of Macrophages in the Maintenance of Intestinal Homeostasis." Journal of Immunology Research 2019 (March 18, 2019): 1–8. http://dx.doi.org/10.1155/2019/1512969.

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Intestinal macrophages constitute the largest pool of macrophages in the body and have emerged as crucial sentinels for pathogen recognition and elimination. The source and development of intestinal macrophages, as well as their distinct properties have been well documented. Intestinal macrophages exert their functions in the maintenance of intestinal homeostasis by shaping host-microbiota symbiosis, managing gut inflammation, crosstalking with T cells, and facilitating wound repair. Recently, nutritional regulation of intestinal macrophages has attracted substantial attention and is becoming

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23

Sears, Cynthia L. "Enterotoxigenic Bacteroides fragilis: a Rogue among Symbiotes." Clinical Microbiology Reviews 22, no. 2 (2009): 349–69. http://dx.doi.org/10.1128/cmr.00053-08.

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SUMMARY Enterotoxigenic Bacteroides fragilis (ETBF) strains are strains of B. fragilis that secrete a 20-kDa heat-labile zinc-dependent metalloprotease toxin termed the B. fragilis toxin (BFT). BFT is the only recognized virulence factor specific for ETBF. ETBF strains are associated with inflammatory diarrheal disease in children older than 1 year of age and in adults; limited data suggest an association of ETBF colonization with inflammatory bowel disease flare-ups and colorectal cancer. ETBF secretes one of three highly related BFT isoforms. The relationship between BFT isoform and disease

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Chen, Yuezhou, Neha Chaudhary, Nicole Yang, et al. "Microbial symbionts regulate the primary Ig repertoire." Journal of Experimental Medicine 215, no. 5 (2018): 1397–415. http://dx.doi.org/10.1084/jem.20171761.

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The ability of immunoglobulin (Ig) to recognize pathogens is critical for optimal immune fitness. Early events that shape preimmune Ig repertoires, expressed on IgM+ IgD+ B cells as B cell receptors (BCRs), are poorly defined. Here, we studied germ-free mice and conventionalized littermates to explore the hypothesis that symbiotic microbes help shape the preimmune Ig repertoire. Ig-binding assays showed that exposure to conventional microbial symbionts enriched frequencies of antibacterial IgM+ IgD+ B cells in intestine and spleen. This enrichment affected follicular B cells, involving a diver

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Semydotska, Zh, I. Chernyakova, and O. Avdeyeva. "Kidneys and microbiota." Ukrainian Journal of Nephrology and Dialysis, no. 1(65) (November 14, 2019): 48–57. http://dx.doi.org/10.31450/ukrjnd.1(65).2020.07.

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The review article analyzes the results of studies of the bi-directional relationship of the intestinal microbiota and kidneys, the so-called colorenal interactive axis of interaction. The intestinal microbiota is considered as a kind of organ that influences the brain, cardiovascular and immune systems, as well as the kidneys of the "host". Short-chain fatty acids (SCFA) formed in the colon as the result of microbial metabolism from plant components of dietary fiber and acting as ligands for the olfactory receptor, paired G-proteins in the kidneys are recognized as the markers of this symbios

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Pickard, Joseph M., and Alexander V. Chervonsky. "Intestinal Fucose as a Mediator of Host–Microbe Symbiosis." Journal of Immunology 194, no. 12 (2015): 5588–93. http://dx.doi.org/10.4049/jimmunol.1500395.

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Tarnecki, A. M., F. A. Burgos, C. L. Ray, and C. R. Arias. "Fish intestinal microbiome: diversity and symbiosis unravelled by metagenomics." Journal of Applied Microbiology 123, no. 1 (2017): 2–17. http://dx.doi.org/10.1111/jam.13415.

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Fast, David, Kristina Petkau, Meghan Ferguson, et al. "Vibrio cholerae-Symbiont Interactions Inhibit Intestinal Repair in Drosophila." Cell Reports 30, no. 4 (2020): 1088–100. http://dx.doi.org/10.1016/j.celrep.2019.12.094.

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Palmer-Young, Evan C., Thomas R. Raffel, and Quinn S. McFrederick. "Temperature-mediated inhibition of a bumblebee parasite by an intestinal symbiont." Proceedings of the Royal Society B: Biological Sciences 285, no. 1890 (2018): 20182041. http://dx.doi.org/10.1098/rspb.2018.2041.

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Competition between organisms is often mediated by environmental factors, including temperature. In animal intestines, nonpathogenic symbionts compete physically and chemically against pathogens, with consequences for host infection. We used metabolic theory-based models to characterize differential responses to temperature of a bacterial symbiont and a co-occurring trypanosomatid parasite of bumblebees, which regulate body temperature during flight and incubation. We hypothesized that inhibition of parasites by bacterial symbionts would increase with temperature, due to symbionts having highe

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Ge, Doudou, Chongwen Yin, Jiayu Jing, Zhihong Li, and Lijun Liu. "Relationship Between the Host Plant Range of Insects and Symbiont Bacteria." Microorganisms 13, no. 1 (2025): 189. https://doi.org/10.3390/microorganisms13010189.

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The evolution of phytophagous insects has resulted in the development of feeding specializations that are unique to this group. The majority of current research on insect palatability has concentrated on aspects of ecology and biology, with relatively little attention paid to the role of insect gut symbiotic bacteria. Symbiont bacteria have a close relationship with their insect hosts and perform a range of functions. This research aimed to investigate the relationship between insect host plant range and gut symbiotic bacteria. A synthesis of the extant literature on the intestinal commensal b

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Bhunia, Rima, Varsha Singh, Srijan Das, Anindya Krishna Basu, and Dolanchapa Sikdar. "PROBIOTICS: A SIGNIFICANT APPROACH TO HEALTH." International Journal of Engineering Applied Sciences and Technology 7, no. 11 (2023): 104–13. http://dx.doi.org/10.33564/ijeast.2023.v07i11.019.

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This report deals with the study that Probiotics have been with us for as long as people have eaten fermented milks, but their collaboration with health benefits have only come in the century when Metchnikoff gave idea of replacing dangerous microbes by useful ones in order to modify our gut flora. Later based on assumption that colonization of the gut was essential, used intestinal strains of Lactobacillus acidophilus for treatment of constipation, digestive hazards. According to Food and agriculture organisation of United Nations (UN) probiotics are live microorganisms which on administering

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Solomon, Alla, and Yurii Polyevoda. "PROBIOTICS AND THEIR ROLE IN THE PRODUCTION OF SPIRITUAL PRODUCTS OF SPECIAL PURPOSE." ENGINEERING, ENERGY, TRANSPORT AIC, no. 3(106) (November 29, 2019): 56–65. http://dx.doi.org/10.37128/2520-6168-2019-3-7.

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In ensuring the proper functioning of the human body, an important role is played by the microorganisms that enter into it with symbiosis. Between them and the microorganism - symbiote, special relationships are formed, including metabolism exchange, internal ecological relations are created, which is a prerequisite for the existence of the macroorganism. These microorganisms ferment nutrients that have not been digested in the upper gastrointestinal tract, forming a variety of chemical compounds that exert both a positive and a negative effect on the human body. Disturbance of normal activity

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HU, Haiming, Ke LAN, and Hongtao LIU. "Human symbiont Bacteroides xylanisolvens attenuates NASH through intestinal nicotine catabolism." Chinese Journal of Natural Medicines 21, no. 2 (2023): 81–82. http://dx.doi.org/10.1016/s1875-5364(23)60387-5.

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Cowan, Courtney M., and Eric M. Pietras. "From symbiote to bad neighbor: The intestinal microbiome as a driver of CHIP." Cell Stem Cell 32, no. 7 (2025): 1036–37. https://doi.org/10.1016/j.stem.2025.06.003.

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Rutz, Sascha, Christian Neumann, Jonas Blume, Axel Kalies, and Alexander Scheffold. "c-Maf-dependent Treg cell control of intestinal TH17 cells and IgA establishes host-microbiota homeostasis." Journal of Immunology 202, no. 1_Supplement (2019): 57.19. http://dx.doi.org/10.4049/jimmunol.202.supp.57.19.

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Abstract Foxp3+T regulatory (Treg) cells are crucial to maintain immune homeostasis both in lymphoid and non-lymphoid tissues. Here we demonstrate that the ability of intestinal Treg cells to constrain microbiota-dependent interleukin 17–producing T helper cell (TH17) and immunoglobulin A (IgA) responses critically required the expression of the transcription factor c-Maf. The terminal differentiation and function of several intestinal Treg cell populations, including RORgt+Tregcells and T follicular regulatory cells, was c-Maf-dependent. c-Maf controlled Treg cell-derived interleukin 10 (IL-1

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Barra, Nicole G., Fernando F. Anhê, Joseph F. Cavallari, Anita M. Singh, Darryl Y. Chan, and Jonathan D. Schertzer. "Micronutrients impact the gut microbiota and blood glucose." Journal of Endocrinology 250, no. 2 (2021): R1—R21. http://dx.doi.org/10.1530/joe-21-0081.

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Micronutrients influence hormone action and host metabolism. Dietary minerals, trace elements, and vitamins can alter blood glucose and cellular glucose metabolism, and several micronutrients are associated with the risk and progression of type 2 diabetes. Dietary components, microbes, and host immune, endocrine, and metabolic responses all interact in the intestine. There has been a focus on macronutrients modifying the host-microbe relationship in metabolic disease. Micronutrients are positioned to alter host-microbe symbiosis that participates in host endocrine control of glucose metabolism

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Pickard, Joseph M., Corinne F. Maurice, Melissa A. Kinnebrew, et al. "Rapid fucosylation of intestinal epithelium sustains host–commensal symbiosis in sickness." Nature 514, no. 7524 (2014): 638–41. http://dx.doi.org/10.1038/nature13823.

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Brown, Eric M., Xiaobo Ke, Daniel Hitchcock, et al. "Bacteroides-Derived Sphingolipids Are Critical for Maintaining Intestinal Homeostasis and Symbiosis." Cell Host & Microbe 25, no. 5 (2019): 668–80. http://dx.doi.org/10.1016/j.chom.2019.04.002.

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Fehér, János, Illés Kovács, Elena Pacella, and Zsolt Radák. "Microbiota–host symbiosis in the pathophysiology and treatment of irritable bowel, irritable eye and irritable mind syndrome." Orvosi Hetilap 155, no. 37 (2014): 1454–60. http://dx.doi.org/10.1556/oh.2014.29987.

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Accumulating clinical evidence supports co-morbidity of irritable bowel, irritable eye and irritable mind symptoms. Furthermore, perturbation of the microbiota–host symbiosis (dysbiosis) is considered a common pathogenic mechanism connecting gastrointestinal, ocular and neuropsychiatric symptoms. Consequently, maintaining or restoring microbiota–host symbiosis represents a new approach to treat these symptoms or to prevent their relapses. Current treatment approach assigned a primary role to live probiotics alone or in combination with prebiotics to enhance colonization of beneficial bacteria

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Zharikova, Ekaterina, T. Boyko, Nadezhda Lescheva, and Vasiliy Vlasenko. "“SYMBION-D” INFLUENCE ON THE INTESTINE MICROBIAL COMPOSITION AND IMMUNITY OF CALVES WITH DYSPEPSIA." Bulletin of KSAU, no. 6 (January 22, 2025): 130–37. https://doi.org/10.36718/1819-4036-2023-6-130-137.

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The purpose of research is to study the effect of a biologically active composition of microbial origin (BACMO) “Symbion-D” on the microbial composition of the intestine and the immunity of calves with dyspepsia. The studies were carried out on calves of the Holstein breed of the neonatal period, belonging to the Federal State Unitary Enterprise Omskoye. The criteria for inclusion in the experimental group of animals was the clinical sign "diarrhea". The calves of the experimental group were fed BACMO “Symbion-D” daily for 5–7 days individually, depending on the weight of the calf and the seve

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Sonnenburg, J. L. "Glycan Foraging in Vivo by an Intestine-Adapted Bacterial Symbiont." Science 307, no. 5717 (2005): 1955–59. http://dx.doi.org/10.1126/science.1109051.

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Jovandaric, Miljana Z., Stefan Dugalic, Sandra Babic, et al. "Programming Factors of Neonatal Intestinal Dysbiosis as a Cause of Disease." International Journal of Molecular Sciences 24, no. 6 (2023): 5723. http://dx.doi.org/10.3390/ijms24065723.

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The intestinal microbiota consists of trillions of bacteria, viruses, and fungi that achieve a perfect symbiosis with the host. They perform immunological, metabolic, and endocrine functions in the body. The microbiota is formed intrauterine. Dysbiosis is a microbiome disorder characterized by an imbalance in the composition of the microbiota, as well as changes in their functional and metabolic activities. The causes of dysbiosis include improper nutrition in pregnant women, hormone therapy, the use of drugs, especially antibiotics, and a lack of exposure to the mother’s vaginal microbiota du

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Emelyanov, D. "PATHOGENETIC AXIS OF ORAL AND GUT MICROBIOMES UNDER THE TREATMENT OF PERIODONTAL LESION IN PATIENTS WITH NON-ALCOHOLIC FATTY LIVER DISEASE." Znanstvena misel journal, no. 90 (May 27, 2024): 27–33. https://doi.org/10.5281/zenodo.11358121.

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NAFLD is also characterized by the formation of a pathogenetic axis between the oral and intestinal microbiomes. <em>Materials and methods.</em> The main group consisted of 44 patients with NAFLD, control group - 20 healthy patients. Clinical dental examination, determination of intestinal microbiota and periodontal pathogens was performed according 1 visit, after 7 days and after 3 months. The levels of gingipain-K and endotoxin in the oral fluid were determined at visits 1 and 3. <em>Results.</em> In the intestinal microbiome in NAFLD, the Firmicutes phylotype prevailed over Bacteroides. The

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Cao, Ruige, Xing Wu, Hui Guo, et al. "Naringin Exhibited Therapeutic Effects against DSS-Induced Mice Ulcerative Colitis in Intestinal Barrier–Dependent Manner." Molecules 26, no. 21 (2021): 6604. http://dx.doi.org/10.3390/molecules26216604.

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Naringin is a kind of multi-source food additive which has been explored broadly for its various biological activities and therapeutic potential. In the present study, the protective effect and mechanism of naringin on dextran sulfate sodium (DSS)-induced ulcerative colitis (UC) in mice were investigated. The results showed that naringin significantly alleviated DSS-induced colitis symptoms, including disease activity index (DAI), colon length shortening, and colon pathological damage. The tissue and serum secretion of inflammatory cytokines, as well as the oxidative stress, were decreased acc

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Гончар, Н. В., and Н. В. Скрипченко. "PROMISING AREAS OF SCIENTIFIC RESEARCH ON THE PROBLEMS OF INTESTINAL INFECTIONS." Children's medicine of the North-West 11, no. 2 (2023): 50–61. http://dx.doi.org/10.56871/cmn-w.2023.46.73.004.

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Решение современных проблем диагностики и лечения кишечных инфекций у детей определяет важнейшие направления научных исследований, в ряду которых стоят молекулярно- генетические и клинические особенности возбудителей вирусных диарей, совершенствование методов терапии острых гастроэнтеритов вирусной этиологии, молекулярная диагностика токсинпродуцирующих бактериальных кишечных патогенов, биологическая безопасность и кишечные инфекции, прогнозирование антибиотик-ассоциированной диареи и подходы к лечению, клиническое значение диареи условно- патогенной бактериальной этиологии у детей, антибиотик

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Wopereis, Harm, Raish Oozeer, Karen Knipping, Clara Belzer, and Jan Knol. "The first thousand days - intestinal microbiology of early life: establishing a symbiosis." Pediatric Allergy and Immunology 25, no. 5 (2014): 428–38. http://dx.doi.org/10.1111/pai.12232.

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Palmer-Young, Evan C., Thomas R. Raffel, and Quinn S. McFrederick. "pH-mediated inhibition of a bumble bee parasite by an intestinal symbiont." Parasitology 146, no. 3 (2018): 380–88. http://dx.doi.org/10.1017/s0031182018001555.

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AbstractGut symbionts can augment resistance to pathogens by stimulating host-immune responses, competing for space and nutrients, or producing antimicrobial metabolites. Gut microbiota of social bees, which pollinate many crops and wildflowers, protect hosts against diverse infections and might counteract pathogen-related bee declines. Bumble bee gut microbiota, and specifically abundance ofLactobacillus‘Firm-5’ bacteria, can enhance resistance to the trypanosomatid parasiteCrithidia bombi. However, the mechanism underlying this effect remains unknown. We hypothesized that the Firm-5 bacteriu

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Kim, Girak, Yikun Yao, Zuojia Chen, Chuan Wu, and Michael J. Lenardo. "Mucus sialylation determines intestinal host-commensal homeostasis." Journal of Immunology 210, no. 1_Supplement (2023): 227.02. http://dx.doi.org/10.4049/jimmunol.210.supp.227.02.

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Abstract Intestinal mucus forms the first line of defense against bacterial invasion while providing nutrition to support microbial symbiosis. How the host controls mucus barrier integrity and commensalism is unclear. We show that terminal sialylation of glycans on intestinal mucus by ST6GALNAC1 (ST6), the dominant sialyltransferase specifically expressed in goblet cells and induced by microbial pathogen-associated molecular patterns, is essential for mucus integrity and protecting against excessive bacterial proteolytic degradation. Glycoproteomic profiling and biochemical analysis of ST6 mut

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Madách, Krisztina, Katalin Kristóf, Eszter Tulassay, et al. "Mucosal Immunity and the Intestinal Microbiome in the Development of Critical Illness." ISRN Immunology 2011 (November 24, 2011): 1–12. http://dx.doi.org/10.5402/2011/545729.

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The intestinal community, including the commensal microbial flora as well as the host tissues, represents a functional whole in vivo. Under physiological circumstances, this symbiosis brings great benefit for the host; however, critical illness induces profound disturbances in the intestinal ecosystem affecting both procaryotic and eucaryotic members. Today, 25 years after the gut was first described as a motor of multiple organ dysfunction syndrome, the role of the injured splanchnic compartment in the pathomechanism and development of critical illness is still in the first line of research.

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Su, Marcia Shu-Wei, Phaik Lyn Oh, Jens Walter, and Michael G. Gänzle. "Intestinal Origin of SourdoughLactobacillus reuteriIsolates as Revealed by Phylogenetic, Genetic, and Physiological Analysis." Applied and Environmental Microbiology 78, no. 18 (2012): 6777–80. http://dx.doi.org/10.1128/aem.01678-12.

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ABSTRACTLactobacillus reuteriis both a gut symbiont and a stable member of sourdough microbiota. This study employed multilocus sequence analysis and an analysis of host-specific physiological and genetic traits to assign five sourdough isolates to rodent- or human-specific lineages. Comparative genome hybridization revealed that the model sourdough isolate LTH2584 had a genome content very similar to that of the model rodent isolate 100-23. These results demonstrate that sourdough isolates ofL. reuteriare of intestinal origin.

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