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Rozprawy doktorskie na temat „Tb”

Autor: Grafiati
Data publikacji: 4 czerwca 2021
Data aktualizacji: 25 lipca 2025

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1

MacNaughton, April Dawn. "Tuberculosis (TB) storytelling : improving community nursing TB program delivery." Thesis, University of British Columbia, 2015. http://hdl.handle.net/2429/56178.

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This study explores the effectiveness of the traditional First Nations practice of storytelling as a tool in improving Community Health Nurse (CHN) continuing education, regarding tuberculosis (TB) programming in First Nations communities. The first part of this study involves a critical analysis of literature regarding the evolution of Canada’s First Nations policies and health care, and the use of storytelling as a learning tool in Western and First Nations contexts. Informed by critical social justice as a theoretical lens, and decolonising perspectives in health care, the analysis of the l
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2

Dinic, Lana. "Molecular Diagnosis of TB and MDR-TB in HIV-Coinfection in Nigeria." Thesis, Harvard University, 2012. http://dissertations.umi.com/gsas.harvard:10387.

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Tuberculosis (TB) is the most common opportunistic infection in HIV-infected patients and the emergence of drug-resistant tuberculosis (DR-TB) is a growing problem in resource-limited settings (RLS). TB diagnosis in most RLS still depends on smear microscopy for acid-fast bacilli (AFB) while adequate infrastructure for testing drug sensitivity is unavailable. However, molecular diagnostics that detect Mycobacterium tuberculosis (Mtb) DNA and its genetic markers of drug resistance were recently developed. In this thesis I describe the use of a molecular diagnostic, Genotype MTBDRplus, for c
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Kajunguri, Damian. "Modelling the impact of TB superinfection on the dynamics of HIV-TB coinfection." Thesis, Stellenbosch : University of Stellenbosch, 2009. http://hdl.handle.net/10019.1/4070.

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Thesis (MSc (Mathematics))--University of Stellenbosch, 2009.<br>ENGLISH ABSTRACT: In this thesis, a mathematical model describing the interaction between HIV and TB in the presence of TB superinfection is presented. The model takes into account two strains of Mycobacterium tuberculosis (MTB), where one strain is drug-sensitive and the other is resistant to at least one of the first-line anti-tuberculosis drugs. The impact of TB superinfection on the incidence and prevalence of TB in HIV-negative and HIVTB coinfected individuals is evaluated. Various control measures such as condom use,
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FRANCISCO, Samuel Nuno Furtado da Conceição. "Aplicação de sistemas moleculares na detecção rápida de MDR-TB e XDR-TB." Master's thesis, Instituto de Higiene e Medicina Tropical, 2011. http://hdl.handle.net/10362/5625.

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Mycobacterium tuberculosis é o agente etiológico da tuberculose em humanos e segundo as estimativas da Organização Mundial da Saúde, um terço da população mundial está infectada com esta bactéria, calculando-se que no ano de 2008 aproximadamente 9,4 milhões de pessoas contraíram tuberculose activa. Associada a esta tendência, encontra-se o aumento alarmante da incidência de tuberculose resistente aos antibióticos, mais propriamente da tuberculose multirresistente e extensivamente resistente. Nesta Dissertação estudaram-se três sistemas de detecção molecular (INNO-LiPA Rif. TB, Innogenetics, G
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5

Sillah, Dolly Jackson. "Early changes in T cell responses in TB patients during chemotherapy for TB." Thesis, London School of Hygiene and Tropical Medicine (University of London), 2009. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.536815.

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Bistline, Kathryn Lou. "Does the inclusion of the cost and burden of adverse drug reactions associated with drug-resistant TB treatment affect the incremental cost-effectiveness of new treatment regimens? A case study from the introduction of bedaquiline in South Africa National TB Programme." Doctoral thesis, University of Cape Town, 2018. http://hdl.handle.net/11427/28441.

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South Africa has one of the world’s highest burdens of TB, HIV/TB co-infection, and drug-resistant TB. Second-line TB treatment is less effective, more expensive, and more toxic than treatment for drug-sensitive TB. Nearly 1 in every 5 persons who starts treatment for drug-resistant TB in South Africa will die; 1 in every 3 persons who survives treatments experiences permanent, profound hearing loss. For decades there was little progress in TB research, however, and so treatment with old regimens continued despite safety concerns. In 2012 the US and European regulatory authorities approved a n
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7

Denis, Marie F. "Extrapulmonary tuberculosis in HIV-positive and HIV-negative children in Haiti : a hospital-based Investigation." [Tampa, Fla] : University of South Florida, 2005. http://purl.fcla.edu/usf/dc/et/SFE0001404.

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8

Brent, Andrew. "The Kilifi Improving Diagnosis and Surveillance of Childhood TB Study : the KIDS TB Study." Thesis, Imperial College London, 2013. http://hdl.handle.net/10044/1/14399.

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Improving diagnosis and surveillance of childhood TB are key research priorities. We established intensified case finding and state of the art TB diagnostics to investigate the performance of clinical and laboratory tools for childhood TB diagnosis at 2 hospitals in Kenya. We estimated the community incidence of childhood TB using a continuous demographic surveillance survey and detailed surveillance sensitivity analysis. 2041 children were investigated for suspected TB. 70 (3.4%) had bacteriologically confirmed TB, 63 (3.1%) had clinically highly probable TB, and a further 144 (7.1%) were tre
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9

Wasuna, Antonina. "Repositioning fusidic acid for tuberculosis: semi-synthesis of analogues and impact of mycobacterial biotransformation on antibiotic activity." Doctoral thesis, University of Cape Town, 2018. http://hdl.handle.net/11427/28154.

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Tuberculosis (TB), caused by Mycobacterium tuberculosis (Mtb), is one of the leading causes of death globally, especially in low and middle-income countries. TB is primarily a curable disease, with chemotherapy predicated on a combination of four drugs. The increase in multiple forms of drug-resistant TB is a major cause for concern, underpinning the importance of a continuous pipeline of new anti-TB agents. Drug repositioning - that is, the optimization of existing drugs for new therapeutic indications - has shown promise in expanding the therapeutic options for TB chemotherapy. Fusidic acid
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10

de, Jager Veronique Rejean. "Trends in the presenting clinical profile of patients with pulmonary tuberculosis in the Western Cape, 1991 - 2009." University of the Western Cape, 2017. http://hdl.handle.net/11394/6455.

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Magister Public Health - MPH (Public Health)<br>Over the past two decades, despite a growing tuberculosis (TB) epidemic, the South African health system and National TB Programme (NTP) have taken significant steps to ensure improved clinical awareness, early diagnosis, prompt treatment initiation and follow-up of treatment outcomes in cases of TB. The effects of these programmatic measures over time on changes in the severity of disease and presenting clinical profile of patients with pulmonary TB have not been studied. Doing so may provide another window on the impact of TB control initiative
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11

Wanyama, Barasa Alex. "Determinants of TB treatment adherence among patients on anti-TB treatment in Tororo District, Uganda." University of the Western Cape, 2017. http://hdl.handle.net/11394/6066.

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Magister Public Health - MPH (Public Health)<br>To address this challenge, our study was to ascertain the extent of poor adherence to anti-TB treatment, to describe the demographic factors of patients on anti-TB treatment, to investigate the factors associated with poor adherence to anti-TB treatment in Tororo district, and to make respective recommendations to improve adherence to anti-TB treatment in order to contribute to the reduction of the TB burden in the world.
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12

Trottier, Danielle. "Mécanismes de transfert d'énergie Eu²⁺ - Tb³⁺ et Ce³⁺ - Tb³⁺ dans des fluorures de type KYF." 63-Aubière : Impr. U.E.R. Sci, 1986. http://catalogue.bnf.fr/ark:/12148/cb361103639.

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13

Kakili, Tuwilika. "Factors that contribute to treatment defaulting amongst tuberculosis patients in Windhoek district, Namibia." Thesis, University of the Western Cape, 2010. http://etd.uwc.ac.za/index.php?module=etd&action=viewtitle&id=gen8Srv25Nme4_2049_1363356699.

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<p>Background: Tuberculosis (TB) is a resurgent disease in many parts of the world, fuelled by HIV/AIDS and poverty. According to WHO, over two billion people were estimated to be infected by TB globally, 9.4 million new cases of TB were reported, while about 1.7 million people were estimated to have lost their lives to TB in 2009 (WHO, 2010). The&nbsp<br>global defaulter rate for TB was estimated at about 9% in 2007 (WHO, 2007). With Africa remaining the global epicentre of the TB epidemic, the epidemic in Sub-Saharan Africa,&nbsp<br>one of the worst affected areas in the world, shows no evid
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14

Deffur, Armin. "The transciptomic landscape of HIV-TB." Doctoral thesis, University of Cape Town, 2013. http://hdl.handle.net/11427/3377.

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Includes abstract.<br>Includes bibliographical references.<br>The thesis consists of four main parts. In Part 1 of this thesis I provide a broad overview of HIVTB with an emphasis on systems approaches followed by an overview of a systems-level study aiming at addressing hypotheses relating to transcriptional differences in active tuberculosis and HIV-1 infection, measured in blood and the site of disease in tuberculous pericarditis. The final chapter in this part describes the methods used to generate and analyse the systems-level data, with emphasis on microarray data generation and analysis
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15

Sattar, Shahra. "Influence of HIV, smoking and hyperglycaemia on the reporting of TB symptoms in a TB prevalence survey." Master's thesis, University of Cape Town, 2013. http://hdl.handle.net/11427/3065.

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Includes abstract.<br>Includes bibliographical references.<br>Finding and treating cases [of tuberculosis] in the community before they present to health facilities, a strategy known as active-case-finding is gaining momentum as a way to decrease the infectious pool. This can be achieved through door-to-door community surveys using a TB symptom-screening questionnaire, and is an economical and practical tool to employ in poor, high burden areas. However, unlike for the high risk group of people infected with HIV, there is a lack of evidence supporting the adaptation of a symptom screening tool
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16

Mabhula, Amanda N. "Investigating permeation of anti-mycobacterial agents in Mycobacterium tuberculosis and M. tuberculosis-infected macrophages in vitro as a model for early stage tuberculosis drug discovery." Doctoral thesis, Faculty of Science, 2021. http://hdl.handle.net/11427/33768.

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Tuberculosis (TB) is the leading cause of death due to a single infectious disease and remains a major threat to global public health. The increasing emergence of multi-drug resistance to current anti-TB drugs, exacerbated by the long treatment duration, highlights the need for new effective treatments or strategies to shorten the treatment duration, improve patient adherence and curb the alarming rates of resistance. A key challenge to current strategies employed in the development of anti-TB drugs is the complexity in TB disease pathology which presents as a wide spectrum of lesions in patie
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17

Blomberg, Thomas R. "Heat conduction in two and three dimensions : computer modelling of building physics applications /." Lund : Dept. of Building Physics [Institutionen för byggnadsteknik], Univ, 1996. http://www.byfy.lth.se/Publikationer/1000pdf/TB-1008.pdf.

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18

Davies, Helen Catherine. "Bovine TB in badgers : a spatial analysis." Thesis, University of Bristol, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.289778.

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Fryatt, Robert John. "Cost effectiveness of TB services in Nepal." Thesis, Imperial College London, 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.243793.

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Routin, Eddy. "Local Tb theorems and Hardy type inequalities." Phd thesis, Université Paris Sud - Paris XI, 2011. http://tel.archives-ouvertes.fr/tel-00656023.

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In this thesis, we study local Tb theorems for singular integral operators in the setting of spaces of homogeneous type. We give a direct proof of the local Tb theorem with L^2 integrability on the pseudo- accretive system. Our argument relies on the Beylkin-Coifman-Rokhlin algorithm applied in adapted Haar wavelet basis and some stopping time results. Motivated by questions of S. Hofmann, we extend it to the case when the integrability conditions are lower than 2, with an additional weak boundedness type hypothesis, which incorporates some Hardy type inequalities. We study the possibility of
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21

Rocha, Chrystianne. "Gap filler adaptativo para sistema ISDB-Tb." Universidade Presbiteriana Mackenzie, 2014. http://tede.mackenzie.br/jspui/handle/tede/1440.

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Made available in DSpace on 2016-03-15T19:37:50Z (GMT). No. of bitstreams: 1 Chrystianne Rocha.pdf: 2924776 bytes, checksum: a1d74db138a8b87f0518f3a6ef67c404 (MD5) Previous issue date: 2014-08-07<br>This master thesis presents the proposal of assigning the cognitive ability to a gap filler. Differently from the usual repeaters found on the market, the adaptive gap filler is able to automatically monitor tuned channels with the intention of verifying if the protection ratio described in Resolution nº398 from Anatel is being respected. Spectrum sensing techniques and the concepts related to co
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22

Kolotylo, T. R. "Clinical features of combined HIV/TB infection." Thesis, БДМУ, 2021. http://dspace.bsmu.edu.ua:8080/xmlui/handle/123456789/18885.

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Marsay, Leanne. "Evaluation of immune correlates to TB vaccines." Thesis, University of Oxford, 2011. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.572645.

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Development of an improved TB vaccine is hindered by the lack of a correlate of ,~.-r protection. Efficacy of TB vaccines in humans can only be a"S~essed by expensive and time consuming trials within TB endemic areas, which are limited; therefore, it is critical that vaccines with the greatest potential to protect are selected for these trials. Mycobacterial growth inhibition assays (MGIAs) have been developed with the hope that these in vitro functional assays will correlate with protection, which could aid in the selection of the best vaccine candidates. Work in this thesis describes the dev
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24

Ali, Hanan M. "Development of new diagnostic devices for TB." Thesis, Bangor University, 2015. https://research.bangor.ac.uk/portal/en/theses/development-of-new-diagnostic-devices-for-tb(5a962fb1-76f7-45ec-b9d6-4b7e30749136).html.

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The main objective of the work was to develop an analytical method for the diagnosis of human and bovine TB+ and para-TB by finding the best Ag with high Ab binding signal. This was achieved in five parts. First, the synthesis of S,S-trans-alkene-methoxy mycolic acid (I) from M. tb was achieved successfully. This led to the synthesis of its glycolipid derivatives (TDM, TMM, GroMM, GMM and ArM). The second part was the analysis of a range of other synthetic Ags using TB+ and TB- human serum samples in ELISA assays. The best combinations of sensitivity and specificity were observed with TDM (160
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Liu, Miaomiao. "Actinomycetes Sourced From Unique Environments as a Promising Source of New TB-Active Natural Products." Thesis, Griffith University, 2017. http://hdl.handle.net/10072/366523.

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Tuberculosis (TB) is the leading cause of death from infectious diseases in the world, affecting more than ten million patients each year. However, multi-drug resistance (MDR-TB) threatens progress achieved in TB care and control, and there are few drugs available to treat MDR-TB. Our overall aim was to identify anti-TB natural products from microbes sourced from unique environments. This thesis presents efforts to achieve an effective approach to identify anti-TB microbial natural products with the combination of one strain many compounds (OSMAC) strategy, NMR fingerprint and principal compon
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Cornick, Ruth. "'You must tune your TB programme well...' : integrating TB, HIV and ARV care in Cape Town primary care setting." Master's thesis, University of Cape Town, 2007. http://hdl.handle.net/11427/9328.

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Includes bibliographical references (leaves 86-91).<br>This study occurred in the context of three problems that have arisen within the South African HIV/AIDS crisis: the prevalent HIV and tubertulosis (TB) co-epidemic, the concern that antiretroviral (ARV) provision might compromise the existing TB control programme, and that the Western Cape's current limited vertical model of ARV roll-out will soon reach capacity. This study evaluated whether and how TB control changed following ARV introduction in a Cape Town primary care TB clinic and explored the process of integration of the TB and ARV
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Akpabio, Ubon S. "A description of patients with recurrence of pulmonary tuberculosis in TB hospital, Ermelo." Thesis, Stellenbosch : University of Stellenbosch, 2015. http://hdl.handle.net/10019.1/97199.

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South Africa is one of the high burden countries for TB in Sub Sahara in Africa with Mpumalanga as one of the provinces with a high burden of disease. Data available on tuberculosis in Msukaligwa indicate the following: Cure Rate 40%; Smear conversion at the end of intensive phase 35% and Defaulter Rate 27.5%. The problem of TB is made worse by the twin epidemic of HIV, with a prevalence of 38.9% in our district -the highest among the 3 districts in the province. Retreatment TB carries the risk of developing TB drug resistance with severe consequences for the patient and the population. Under
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Al, Qublan Hamzeh. "Development and testing of recombinant B. abortus RB51 vaccine strains carrying M. tuberculosis protective antigens." Diss., Virginia Tech, 2015. http://hdl.handle.net/10919/73696.

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Tuberculosis, caused by Mycobacterium tuberculosis, is one of the most prevalent infectious diseases inflicting humankind. The World Health Organization estimates that one third of the world's population, approximately 2.2 billion people, is infected with TB with a mortality of 1.7 million people annually. Currently, the WHO estimates that each year more than 9 million people develop TB. Bacille Calmette-Guérin (BCG), an attenuated strain of M. bovis, is the only licensed TB vaccine in the world. Clinical studies have shown childhood vaccination with BCG to be protective against disseminating
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Adebanjo, Omotayo David. "Knowledge, attittudes and practices of healthcare workers about prevention and control of multidrug-resistant tuberculosis at Botsabelo Hospital Maseru, Lesotho." Thesis, University of Limpopo ( Medunsa Campus), 2011. http://hdl.handle.net/10386/423.

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Thesis (MPH)--University of Limpopo, 2011.<br>Background: Tuberculosis is one of the major public health problems in Lesotho. With the occurrence of multi-drug resistant tuberculosis, little is known about the views of health care workers on this disease. The aim of this study was to investigate the knowledge, attitudes, and practices of healthcare professionals about prevention and control of MDR-TB at Botsabelo hospital, situated in Maseru, Lesotho. Methods: This study was conducted by means of a semi-structured, anonymous, and self-administered questionnaire that was sent to health care wo
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Knight, Lauren Kerry. "Evaluation of the costs of managing cutaneous adverse drug reactions to first-line TB therapy in South African TB patients." Master's thesis, University of Cape Town, 2018. http://hdl.handle.net/11427/27821.

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Background: Optimal tuberculosis (TB) treatment remains the backbone of effective TB control programmes. However, TB drugs are often associated with adverse drug reactions (ADR) that affect treatment adherence and cure. Cutaneous adverse drug reactions (CADR) are more commonly associated with Human Immunodeficiency Virus (HIV)/TB co-infection, occurring in up to 7% of patients. If severe, CADR require treatment interruption and hospitalisation. There are no standardised guidelines for managing CADR to TB therapy. Current practice in South Africa involves drug rechallenge, a process, which aims
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Maserumule, Matsopiane Charlotte. "The development of aptamer-based probes for the detection of TB antigens ESAT-6.CFP-10 potential TB diagnostic tools." Master's thesis, University of Cape Town, 2013. http://hdl.handle.net/11427/3425.

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Includes abstract.<br>Includes bibliographical references.<br>Lack of point-of-care (PoC) diagnostic tools for TB hinders control of the disease, particularly in resource-limited, high HIV and TB prevalence countries. Therefore, there is a need for simple, rapid, accurate, and affordable PoC diagnostics to detect active TB early enough for opportune intervention. To develop TB detection probes that will constitute such diagnostics, our research group recently isolated DNA aptamers that bind to a putative marker for active TB; the ESAT-6.CFP-10 heterodimer. Aptamers are highly specific artifici
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Ncube, Wenzokuhle S. "People’s understanding of TB in a setting of high HIV/TB prevalence: case studies in Gugulethu Township, Western Cape Province." University of the Western Cape, 2014. http://hdl.handle.net/11394/4170.

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Magister Artium (Development Studies) - MA(DVS)<br>Tuberculosis (TB) infection is present in many people but it is sometimes latent until one’s immune system is compromised. As such, it increasingly manifests in people, especially those whose immune system has been compromised by e.g. HIV, as an opportunistic disease. TB is thus closely interlinked with HIV and efforts to eradicate TB have been integrated with the fight against HIV in South Africa. The study revealed that factors such as poverty and stigma - be it enacted or perceived - has an impact on how people with TB deal with the burden
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Olandim, Richard John Lintulahti. "Diversidade espacial na recepção em sistemas ISDB-Tb." Universidade Presbiteriana Mackenzie, 2015. http://tede.mackenzie.br/jspui/handle/tede/1464.

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Made available in DSpace on 2016-03-15T19:37:57Z (GMT). No. of bitstreams: 1 RICHARD JOHN LINTULAHTI OLANDIM.pdf: 2276167 bytes, checksum: 0d3c0536034c612074740ab02558a1be (MD5) Previous issue date: 2015-06-25<br>In Brazil, the broadcasting system for television content in high definition is the ISDB-Tb. Although robust, the content transmission in this system, like in any radio frequency propagation, can suffer from external attenuating factors, such as distortion by multipath propagation. One of the techniques used in radio communications for minimizing the effects of this type of distorti
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Monedero, Recuero Ignacio. "Hacia un mejor control de la tuberculosis multidrogorresistente en países en desarrollo." Doctoral thesis, Universitat Autònoma de Barcelona, 2013. http://hdl.handle.net/10803/401285.

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Introducción La tuberculosis multidrogorresistente (TB-MDR) está incrementando su prevalencia a escala mundial principalmente como consecuencia del mal manejo de los casos sensibles y transmisión primaria. La mayoría de pacientes proceden de países en desarrollo con sistemas de salud insuficientes para el manejo de a sus enfermos. Objetivos El objetivo general de esta tesis doctoral es profundizar en el tema de la TB-MDR en países en desarrollo y aportar nuevos conocimientos que colaboren en la prevención de resistencias medicamentosas y a tratar con mejores resultados a aquellos pacien
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Baker, Allison Rees. "SNP Associations with Tuberculosis Susceptibility in a Ugandan Household Contact Study." Case Western Reserve University School of Graduate Studies / OhioLINK, 2010. http://rave.ohiolink.edu/etdc/view?acc_num=case1274893954.

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Caldwell, Judy. "A programme evaluation of the effects of an intensified TB screening strategy on changes in facility level TB case finding in City Health PHC facilities in Cape Town." University of the Western Cape, 2018. http://hdl.handle.net/11394/6852.

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Master of Public Health - MPH<br>Background: In South Africa, tuberculosis (TB) detection remains a major problem, as notified cases are estimated to account for only 68% of all incident cases. Health services have relied on passive case finding and this leads to missed or delayed diagnosis. In Cape Town, City Health has embarked on an active surveillance programme to systematically screen all adults seeking health care at PHC facilities for active TB, in order to identify undiagnosed incident TB cases and avert missed opportunities for treating TB. Aim: The aim of this study was to
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Frigati, Lisa Jane. "The impact of isoniazid preventative therapy and antiretroviral therapy on tuberculosis (TB) in HIV-infected children in a high TB incidence setting." Master's thesis, University of Cape Town, 2011. http://hdl.handle.net/11427/10467.

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The aim of this study is to investigate the combined effect of IPT [INH preventative therapy] and ART [antiretroviral therapy] on TB incidence in HIV-infected children. A cohort analysis will be performed using data from a prospective, double-blinded placebo controlled trial of INH versus placebo in HIV-infected children in Cape Town, South Africa.
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Ntinginya, Nyanda Elias [Verfasser], and Michael [Akademischer Betreuer] Hölscher. "Evaluation of potential surrogate markers to determine TB treatment response among TB patients in Mbeya, Tanzania / Nyanda Elias Ntinginya ; Betreuer: Michael Hölscher." München : Universitätsbibliothek der Ludwig-Maximilians-Universität, 2017. http://d-nb.info/1131040376/34.

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ALENCAR, Suelene Suassuna Silvestre de. "Translocação e bactérias marcadas com 99m técnécio na icterícia obstrutiva experimental em ratos." Universidade Federal de Pernambuco, 2001. https://repositorio.ufpe.br/handle/123456789/19708.

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Submitted by Fabio Sobreira Campos da Costa (fabio.sobreira@ufpe.br) on 2017-07-17T14:33:57Z No. of bitstreams: 2 license_rdf: 811 bytes, checksum: e39d27027a6cc9cb039ad269a5db8e34 (MD5) Dissertação de Mestrado - Suelene Suassuna Silvestre Alencar.pdf: 1698152 bytes, checksum: 7bc449edbb1386a1875057dc6f3f376f (MD5)<br>Made available in DSpace on 2017-07-17T14:33:58Z (GMT). No. of bitstreams: 2 license_rdf: 811 bytes, checksum: e39d27027a6cc9cb039ad269a5db8e34 (MD5) Dissertação de Mestrado - Suelene Suassuna Silvestre Alencar.pdf: 1698152 bytes, checksum: 7bc449edbb1386a1875057dc6f3f376f (MD5
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Lucca, Maria Elvira Santos de. "Análise epidemiológica da tuberculose e co-infecção HIV/TB, em Ribeirão Preto-SP, de 1998-2006." Universidade de São Paulo, 2008. http://www.teses.usp.br/teses/disponiveis/17/17139/tde-01042008-151419/.

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A pesquisa teve como objetivo analisar o Programa de Controle da Tuberculose (PCT) no município de Ribeirão Preto -São Paulo, no período de 1998 a 2006. Utilizou-se para este propósito indicadores epidemiológicos e de desempenho construídos a partir de dados das fichas de notificação de tuberculose (TB) armazenadas no sistema de informação o EPI-Tb, da Secretaria municipal de saúde deste município e os dados populacionais de estimativas do DATASUS, do período de estudo. Selecionaram-se para o estudo casos novos de TB notificados e residentes no município, por ano de diagnóstico, excluindo-se c
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Tsuro, Urgent. "Modelling the impact of risk factors affecting TB treatment." Thesis, University of Fort Hare, 2013. http://hdl.handle.net/10353/d1019782.

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The Tuberculosis infection rate has been generally escalating due to poor health conditions in the Gweru district of Zimbabwe. The study therefore seeks to identify the risk factors that affect TB treatment in the Gweru district. A cross sectional study was carried out in which a questionnaire was employed for data collection on 113 respondents. A binary logistic regression model was employed for data analysis. A total of 98 TB patients were interviewed: [50 respondents (44.0%) had Multi-drug resistant Tuberculosis and 63 respondents (56.0%) had general Tuberculosis). Before being enrolled int
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Visser, Hanri. "Mechanisms of resistance to new generation anti-TB drugs." Thesis, Stellenbosch : Stellenbosch University, 2015. http://hdl.handle.net/10019.1/96863.

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Thesis (MScMedSc)--Stellenbosch University, 2015.<br>ENGLISH ABSTRACT: Drug resistance in Mycobacterium tuberculosis is an increasing global problem. Drug resistance is mostly caused by single nucleotide polymorphisms (SNPs) within the bacterial genome. This observed increase in global incidence of drug resistant tuberculosis (TB) has sparked the search for new anti-TB drugs and the repurposing of drugs that are currently used against other organisms or species of mycobacteria. One such repurposed drug, clofazimine (CFZ), is currently used for the treatment of leprosy, caused by Mycobacterium
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Medina, Nilberto Heder. "Momentos magnéticos de estados nucleares do \'ANTPOT.159 Tb\'." Universidade de São Paulo, 1992. http://www.teses.usp.br/teses/disponiveis/43/43131/tde-04102012-153339/.

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Foram medidos os momentos magnéticos dos estados da banda rotacional do estado fundamental do ANTPOT 159 Tb, através da técnica da distribuição angular perturbada, utilizando-se o campo magnético transiente. Os estados do ANTPOT. 159 Tb foram populados via excitação coulombiana com feixe de ANTPOT. 35 Cl a 88 Me V, sendo os raios -y, emitidos na desexcitação dos estados, observados em coincidência com as partículas retroespalhadas do feixe. Os momentos magnéticos medidos neste trabalho, foram comparados com as previsões de modelos híbridos (rotor+partícula e rotor triaxial+quase-partícula), no
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Giannopoulos, Mihail. "Tunable bandwidth quantum well infrared photo detector (TB-QWIP)." Thesis, Monterey, Calif. : Springfield, Va. : Naval Postgraduate School ; Available from National Technical Information Service, 2003. http://library.nps.navy.mil/uhtbin/hyperion-image/03Dec%5FGiannopoulos.pdf.

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Thesis (M.S. in Applied Physics)--Naval Postgraduate School, December 2003.<br>Thesis advisor(s): Gamani Karunasiri, James Luscombe. Includes bibliographical references (p. 59-61). Also available online.
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Ansa, Gloria Akosua. "Integration of tuberculosis (TB) and HIV services in Ghana." Thesis, University of Leeds, 2011. http://etheses.whiterose.ac.uk/2419/.

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Integration of health services involves managing services to enhance quality for patient needs that cut across multiple services, providers and settings. The rapid growth of human immunodeficiency virus (HIV) has increased tuberculosis (TB) cases, and TB/HIV integration offers a unified strategy for control. This study evaluated TB/HIV integration in Ghana. The three sites evaluated applied varying degrees of integration. A mixed methods approach comprised an uncontrolled before-and-after study involving 1330 TB cases, and qualitative interviews with 29 providers and patients. TB treatment suc
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Patel, Ravikumar. "Rapid PCR TB Testing Results in 66% Reduction in Total Isolation Days in Smear Positive Patients." Thesis, The University of Arizona, 2018. http://hdl.handle.net/10150/626867.

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Yang, Christine K. "Using age of infection models to derive an explicit expression for Ro." Thesis, University of British Columbia, 2007. http://hdl.handle.net/2429/447.

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Using a multiple stage age of infection model, we derive an expression for the basic reproduction number, Ro. We apply this method to find Ro in analogous treatment models. We find, in the model without treatment, Ro depends only on the mean infective period, and not on the infective distribution. In treatment models, Ro depends on the mean infective and mean treatment period, as well as the distribution of the infective period, but not on the distribution of the treatment period. With an explicit formula for Ro and the final size relation, we provide a practical alternative to evaluating the
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Cervino, Alessandra C. L. "Genetic susceptibility to tuberculosis : an analytical and experimental analysis." Thesis, University of Oxford, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.326112.

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Raphela, Mabule Lucas. "Targeted depletion of RibF, a putative bifunctional FAD synthetase/ flavokinase in Mycobacterium smegmatis using CRISPR interference." Master's thesis, Faculty of Health Sciences, 2020. http://hdl.handle.net/11427/32943.

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Tuberculosis (TB) is the leading killer globally owing to an infectious disease. There is consequently an urgent need to develop novel TB drugs and shorter regimens to treat the causative agent, Mycobacterium tuberculosis, an imperative which demands the identification of new drug targets in essential mycobacterial pathways. To that end, the work presented in this dissertation aimed to functionally characterize ribF, an essential gene in the mycobacterial riboflavin (RF; vitamin B2) biosynthetic pathway. Given the role of RF as a core component of the essential flavin cofactors, flavin mononuc
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Motamen, Seyedehsara. "Synthesis of a new compound class of anti-tuberculosis natural products." Thesis, Griffith University, 2021. http://hdl.handle.net/10072/408500.

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Tuberculosis (TB) is an infectious disease caused by Mycobacterium tuberculosis. It usually affects the lungs (pulmonary TB) but can also affect other parts of the body (extrapulmonary TB). According to the World Health Organisation (WHO) report in 2020, TB is one of the top ten leading causes of death worldwide and the main cause of death from infectious disease, ranked above HIV/AIDS. TB treatment is challenging and requires early diagnosis, effective chemotherapy regimens, and drug-resistance screening. Therefore, development of shorter and simpler drug regimens that are safe, suitable for
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