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Rozprawy doktorskie na temat „Terminal 2”

Autor: Grafiati

Data publikacji: 28 lipca 2024

Data aktualizacji: 31 lipca 2025

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1

Ang, Hwee Ngoh. "Modelling and characterisation of 2-terminal heterojunction phototransistors." Thesis, University of Surrey, 2005. http://epubs.surrey.ac.uk/843728/.

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A Heterojunction Phototransitor (HPT) is an attractive high-speed photodetector for optical communications, as it can provide high gain and high power. It can also be used to generate millimetre-wave signals using optical heterodyne for radio astronomy and wireless broad-band communications. Edge illuminated 2-terminal HPTs (2T-HPTs) integrated with an optical waveguide are designed and characterised. A small signal model is developed and it simulates the 2T-HPT frequency responses with good accuracy and supplements the measurement to determine its gain and cut-off frequency. This overcomes th

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2

Shao, Jin. "Notch signalling pathway regulates the terminal differentiation of osteoblasts." Thesis, Queensland University of Technology, 2018. https://eprints.qut.edu.au/119172/2/Jin_Shao_Thesis.pdf.

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This project contributes to our understanding of bone cell biology and sheds light on the potential therapeutic application of Notch signalling pathway on bone-related diseases. The thesis was a step forward in answering how bone cells communicate with each other and determinate their own fates. It provides the first evidence demonstrating Notch signalling is critical in bone cell functions.

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Silva, Antônio Marcos Vargas da. "Disfunção endotelial na insuficiência renal terminal e no diabetes tipo 2." reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2008. http://hdl.handle.net/10183/13140.

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Vários estudos envolvendo a avaliação da função endotelial em pacientes com insuficiência renal terminal (IRT) e em pacientes com diabetes tipo 2 (DM2) têm sido apresentados objetivando um melhor entendimento dos mecanismos fisiopatológicos e das condições que cercam essas patologias. As sessões de hemodiálise (HD) em pacientes com IRT e a microalbuminúria em pacientes com DM2 influenciam as respostas endoteliais e, diante disso, este trabalho constitui-se de dois estudos independentes com ambas as populações, sendo: o Estudo 1 objetivou avaliar a influência de uma sessão de HD na função endot

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4

Galal, Daria, and Martin Tillberg. "Security Test of iZettle's Reader 2 : A card terminal for safe payments?" Thesis, KTH, Skolan för elektroteknik och datavetenskap (EECS), 2020. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-277913.

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Ethical hacking and penetration testing are two methods often used when organizations and companies want to measure their level of information security, and find out if there are additional steps that can be taken in order to increase the security. This report describes a security test of the card terminal iZettle Reader 2, with the intention to examine its level of security based on the device’s frequent appearance in the society. The implementation is divided into three phases: prestudy and threat modelling, penetration testing and evaluation and conclusion of the security. The threat model

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5

Prata, Henrique Moraes. "Enfermidade e infinito: direitos da personalidade do paciente terminal." Universidade de São Paulo, 2012. http://www.teses.usp.br/teses/disponiveis/2/2131/tde-15042013-111929/.

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O presente trabalho apresenta uma nova perspectiva para as discussões jurídicas e bioéticas acerca dos direitos da personalidade dos pacientes terminais e encontra em nosso ordenamento jurídico, na afirmação de um direito geral da personalidade, a plenitude da tutela civil dos bens jurídicos personalíssimos do enfermo, sobretudo nas etapas finais da doença, ocasião em que a hipermedicalização do processo de morrer destaca-se como o principal fator gerador de lesões de diversas naturezas a esses bens. No caminho para chegarmos à proteção geral da personalidade, examinamos alguns direitos especi

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6

Chawla, Ayesha. ""C-Terminal Binding Protein 2" an emerging oncogene in colon and pancreatic cancers." VCU Scholars Compass, 2017. https://scholarscompass.vcu.edu/etd/5163.

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The C terminal binding proteins (CtBP) 1 and 2 are a family of transcriptional co-repressors overexpressed in a variety of cancers, and are frequently associated with poor prognosis and chemoresistance. CtBP has also been characterized in cell culture models as drivers of migration/invasion and epithelial-mesenchymal transition. CtBP mediates its transcriptional corepressor activity via its dehydrogenase domain, and inhibition of this domain interferes with CtBP oncogenic functions. The role of CtBP in APC mutant neoplasia remains obscure even though APC is responsible for degradation of both

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7

Baker, Emma Louise. "The role of the long terminal repeat (LTR) in the pathogenesis of human immunodeficiency virus type 2 (HIV-2)." Thesis, University College London (University of London), 2004. http://discovery.ucl.ac.uk/1446725/.

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Recent data has indicated that the prolonged asymptomatic phase and freedom from clinical illness experienced by the majority of HIV-2 infected individuals results from a lower level of virus production during infection than that observed in either HIV-1 infection or in the small number of HIV-2 infected individuals displaying relatively rapid progression to disease. The rate at which viral gene products are transcribed is one mechanism by which the rate of virus production can be controlled and is mediated by the Long Terminal Repeat (LTR) regions of the HIV-2 genome. A limiting dilution sens

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8

Leinenweber, Ariane [Verfasser]. "Regulation of Excitatory Amino Acid Transporter 2 (EAAT2) by Carboxy-terminal Domains / Ariane Leinenweber." Hannover : Bibliothek der Tierärztlichen Hochschule Hannover, 2010. http://d-nb.info/100962427X/34.

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9

Tang, Hui-yuan. "Role of C-terminal 18 amino acids for the biological activity of prostaglandin endoperoxide H synthase-2." Diss., Connect to online resource - MSU authorized users, 2007.

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Thesis (Ph. D.)--Michigan State University. Dept. of Biochemistry and Molecular Biology, 2007.<br>Title from PDF t.p. (viewed Aug. 17, 2009). Includes bibliographical references (p. 114-125). Also issued in print.

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10

KOJIMA, KIYOHIDE, HIROMU NAKAMURA, and SHONEN YOSHIDA. "Occurrence of a Terminal Deoxynucleotidyl Transferase-Like Activity in N-2-Fluorenylacetamide-treated Rat Liver." Nagoya University School of Medicine, 1985. http://hdl.handle.net/2237/17476.

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11

Abbenseth, Josh. "Synthesis of Terminal Transition Metal Pnictide Complexes by Activation of Small Molecules." Doctoral thesis, Niedersächsische Staats- und Universitätsbibliothek Göttingen, 2019. http://hdl.handle.net/21.11130/00-1735-0000-0003-C18F-2.

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12

Ly, Thu, Natalia Moroz, Christopher T. Pappas, et al. "The N-terminal tropomyosin- and actin-binding sites are important for leiomodin 2's function." AMER SOC CELL BIOLOGY, 2016. http://hdl.handle.net/10150/621526.

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Leiomodin is a potent actin nucleator related to tropomodulin, a capping protein localized at the pointed end of the thin filaments. Mutations in leiomodin-3 are associated with lethal nemaline myopathy in humans, and leiomodin-2-knockout mice present with dilated cardiomyopathy. The arrangement of the N-terminal actin- and tropomyosin-binding sites in leiomodin is contradictory and functionally not well understood. Using one-dimensional nuclear magnetic resonance and the pointed-end actin polymerization assay, we find that leiomodin-2, a major cardiac isoform, has an N-terminal actin-binding

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13

Garchar, Kimberly Kay. "A dying community : a Roycean critique of the medical community at the end of life /." view abstract or download file of text, 2006. http://proquest.umi.com/pqdweb?did=1232405801&sid=3&Fmt=2&clientId=11238&RQT=309&VName=PQD.

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Thesis (Ph. D.)--University of Oregon, 2006.<br>Typescript. Includes vita and abstract. Includes bibliographical references (leaves 175-179). Also available for download via the World Wide Web; free to University of Oregon users.

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14

Kunert, Ilka. "Untersuchungen zur N-terminalen Glykierung und Bildung N-terminaler 2(1H)-Pyrazinonstrukturen in Lebensmitteln und in vivo." Doctoral thesis, Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden, 2009. http://nbn-resolving.de/urn:nbn:de:bsz:14-qucosa-23410.

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Sowohl bei der Forschung der Maillard-Reaktion in Lebensmitteln als auch im menschlichen Körper lag das Hauptaugenmerk bislang auf der Reaktion der Carbonylfunktion mit den Aminofunktionen der Seitenketten wie Lysin oder Arginin, da sie in vielen Lebensmitteln oder physiologischen Proteinen die größte Quelle an Aminofunktionen darstellen. Dagegen wurde eine vergleichbare Reaktion mit dem N-Terminus von Aminosäuren, Peptiden oder Proteinen weniger beachtet, obgleich in lysinarmen oder peptidhaltigen Lebensmitteln die N-terminalen Aminofunktionen dominieren und die Seitenketten körpereigener Pro

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15

Lei, Kui. "The Apoptotic Activity of c-Jun NH₂-Terminal Kinase Signal Transduction: A Dissertation." eScholarship@UMMS, 2002. http://escholarship.umassmed.edu/gsbs_diss/246.

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Stress-induced JNK activity has been implicated in apoptosis. Gene disruption studies have established that JNK signaling is required for some forms of apoptosis. However, it was not clear whether and how JNK was able to deliver an apoptotic signal, because JNK and its regulated-downstream transcriptional factors control a variety of gene activities and multiple biological functions. I have studied this question by using constitutively activated JNK that is independent of upstream signaling. The results indicate that activated JNK is sufficient to deliver an apoptotic signal

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16

Funakoshi, Yuuta. "Synthesis of Nitrogen-Containing Compounds from Terminal Alkynes and Sulfonyl Azides via N-Sulfonyl-1,2,3-triazoles." Kyoto University, 2017. http://hdl.handle.net/2433/227636.

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Weigelt, Johan. "Development of new NMR techniques and the structure of the N-terminal domain of Escherichia coli DnaB helicase /." Stockholm, 1999. http://diss.kib.ki.se/1999/91-628-3414-2.

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Opie, Shaun Rueben. "Characterization of mutations in the terminal repeats and capsid proteins of the adeno-associated virus type-2." [Gainesville, Fla.]: University of Florida, 2003. http://purl.fcla.edu/fcla/etd/UFE0000761.

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19

Shay, Daniel Travis. "Synthesis, structure, and reactivity of terminal cobalt imido complexes." Access to citation, abstract and download form provided by ProQuest Information and Learning Company; downloadable PDF file, 134 p, 2007. http://proquest.umi.com/pqdweb?did=1257806121&sid=6&Fmt=2&clientId=8331&RQT=309&VName=PQD.

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Caldwell, Rohm Mackenzie Smyth. "A terminal Middle Woodland ceramic complex from southern Illinois /." Available to subscribers only, 2008. http://proquest.umi.com/pqdweb?did=1594497441&sid=5&Fmt=2&clientId=1509&RQT=309&VName=PQD.

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21

Despres, Typhaine. "Synthesis of hyperbranched polymers with multiple reactive terminal groups by RAFT-SCVP." Electronic Thesis or Diss., Le Mans, 2024. http://www.theses.fr/2024LEMA1022.

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Ce projet vise à élaborer des polymères hyper-ramifiés (HBP) cationiques porteurs de multiples groupements terminaux fonctionnels afin de développer le multi-ciblage cellulaire de nouveaux vecteurs de gènes thérapeutiques. Ces HBP sont prometteurs pour traiter les troubles vasculaires et prévenir les maladies cardio-vasculaires associées à un dysfonctionnement endothélial chez les patients diabétiques. Les HBP, présentant de grands volumes intérieurs et un nombre élevé de groupes terminaux en périphérie, sont le plus souvent limités à un seul type de groupement terminal. La stratégie choisie p

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22

Dowdy, Christopher R. "Runx1 C-terminal Domains During Hematopoietic Development and Leukemogenesis: A Dissertation." eScholarship@UMMS, 2012. https://escholarship.umassmed.edu/gsbs_diss/604.

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Runx1 is a master regulator of hematopoiesis, required for the initiation of definitive hematopoiesis in the embryo and essential for appropriate differentiation of many hematopoietic lineages in the adult. The roles of Runx1 in normal hematopoiesis are juxtaposed with the high frequency of Runx1 mutations and translocations in leukemia. Leukemia associated Runx1 mutations that retain DNA-binding ability have truncations or frame shifts that lose C-terminal domains. These domains are important for subnuclear localization of Runx1 and protein interactions with co-factors. The majority of leukem

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23

Rodella, Umberto. "A novel model of Miller Fisher syndrome to study motor axon terminal regeneration." Doctoral thesis, Università degli studi di Padova, 2017. http://hdl.handle.net/11577/3422774.

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The neuromuscular junction (NMJ) is a ‘tripartite’ synapse, composed of the presynaptic motor axon terminal (MAT), the muscle fiber and perisynaptic Schwann cells (PSCs). NMJ functionality is essential for the execution of body movements and it is anatomically exposed, becoming an easy target of bacterial and animal neurotoxins, toxic chemicals, mechanical trauma, and autoimmune diseases. In the Miller Fisher Syndrome (MFS) autoantibodies against specific gangliosides (>90% GQ1b) bind to MAT and in turn activate the complement system cascade at its surface, leading to nerve degeneration. Such

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24

White, Mary Kathryn. "Certified nursing assistants' feelings of preparedness in caring for nursing home residents at the end of life." Laramie, Wyo. : University of Wyoming, 2007. http://proquest.umi.com/pqdweb?did=1445048331&sid=8&Fmt=2&clientId=18949&RQT=309&VName=PQD.

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Gourmaud, Sarah. "Expression de c-Jun N-terminal kinase (JNK) dans la maladie d'Alzheimer : intérêts diagnostiques et thérapeutiques." Paris 7, 2014. http://www.theses.fr/2014PA077106.

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La maladie d'Alzheimer (MA) se caractérise par l'accumulation de peptides d'amyloïde-β42 (Aß₄₂), de protéine tau hyperphosphorylée (ptau) et une perte neuronale. Les niveaux d'Aß₄₂ et de tau au niveau du liquide céphalo-rachidien (LCR) des patients sont utilisés comme biomarqueurs diagnostique. Les protéines PKR et JNK sont des kinases impliquées dans la production d'AE342, la phosphorylation de tau et la mort neuronale. L'accumulation de leur forme active a été mise en évidence dans le cerveau de patients MA. Il existe trois isoformes de JNK. JNK1 et JNK2 sont ubiquitaires et JNK3 est presque

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26

Gleisner, Martin. "Interaction of he Epsin N-Terminal Homology domain (ENTH) with artificial membranes as a function of lateral tension." Doctoral thesis, Niedersächsische Staats- und Universitätsbibliothek Göttingen, 2016. http://hdl.handle.net/11858/00-1735-0000-0028-8821-2.

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Proteine formen während der Endozytose planare Membranen zu gekrümmten Vesikeln um. Im ersten Schritt dieses Prozesses bindet das Protein Epsin an das Rezeptorlipid Phosphatidylinositol-4,5-bisphosphat (PIP<sub>2</sub>) und ein vorher ungeordneter Bereich am N-Terminus von Epsin, die <i>epsin N-terminal homology domain</i> (ENTH), bildet eine α-Helix, welche in die Membran insertiert. Im Rahmen dieser Arbeit wurde die Wechselwirkung von ENTH mit PIP<sub>2</sub>-haltigen Lipiddoppelschichten unter Verwendung von <i>bottom up</i> Modellsystemen charakterisiert. Die Affinität von ENTH zu PIP

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27

Reid, Jocelyn. "Fun[c]tions of the N-terminal extensions of the ubiquitin-specific processing protease-testis 1 and 2 isoforms." Thesis, McGill University, 2003. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=19440.

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Ubiquitin is a small, globular 8 kDa protein whose function is accomplished by its conjugation to targeted substrates. This conjugation is a multi-step process involving three different enzymes. Upon polyubiquitination of a target protein, the 26S proteasome is recruited, leading to the degradation of the substrate. The ubiquitination of proteins, and hence their degradation, can be prevented through the action of deubiquitinating enzymes (DUBs), cysteine proteases that cleave the isopeptide bond through which ubiquitin moieties are attached to their substrates. How DUBs recognize their substr

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Holton, Janice Lesley. "Monoclonal antibodies in n-terminal peptide antisera in a study of the structure of desmosmal glycoproteins 2 and 3." Thesis, University of Southampton, 1991. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.316030.

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Melo, Marcelo Maia Caixeta de. "?leo terminal de pacientes submetidos ? colonoscopia: aspectos endosc?picos, histol?gicos e cl?nicos." Faculdade de Medicina de São José do Rio Preto, 2007. http://bdtd.famerp.br/handle/tede/40.

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Made available in DSpace on 2016-01-26T12:51:18Z (GMT). No. of bitstreams: 1 marcelomaiacaixetamelo_dissert.pdf: 1810009 bytes, checksum: 1014c04abf9e0627459b0eaa88a963d8 (MD5) Previous issue date: 2007-10-26<br>The ileum is approximately the most distal three-fifths of the small intestine and is responsible for digestion and the absorption of foods. The diagnosis of diseases that affect this segment can be achieved by clinical evaluation and complementary examinations. Colonoscopy, not only allows macroscopical analysis, but also enables biopsies to be carried out for histological evaluatio

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Le, Hingrat Quentin. "Impact de la variabilité génétique dans la région Long Terminal Repeat et le gène de l'intégrase sur la réplication du VIH-2." Thesis, Université de Paris (2019-....), 2019. https://theses.md.univ-paris-diderot.fr/LE_HINGRAT_Quentin_va.pdf.

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Le VIH-2 est souvent considéré comme un modèle d’infection rétrovirale atténuée, du fait de sa faible réplication virale, des faibles taux de transmission et de la progression plus lente vers le stade SIDA des patients infectés. Les mécanismes causaux de cette moindre physiopathologie sont encore mal connus. Dans ce travail, nous nous sommes intéressés à la diversité du VIH-2, notamment dans deux régions génomiques : l’intégrase et la région Long Terminal Repeat (LTR). Nous avons tout d’abord amélioré la technique classique d’isolement de souches virales afin de disposer de davantage de souche

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Nakao, Kayoko. "Knowledge, preferences, and arrangement of end-of-life care and decision-making among Japanese American older adults." Diss., Restricted to subscribing institutions, 2009. http://proquest.umi.com/pqdweb?did=1872935931&sid=1&Fmt=2&clientId=1564&RQT=309&VName=PQD.

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Kugler, Neil. "When curing stops and caring begins : a study of the need for end-of-life care education of future health care workers /." ProQuest subscription required:, 2003. http://proquest.umi.com/pqdweb?did=990270731&sid=1&Fmt=2&clientId=8813&RQT=309&VName=PQD.

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Litteral, Vaughn. "mdm2 Amplification in NIH3T3L1 Preadipocytes Leads to Mdm2 Elevation in Terminal Adipogenesis." Wright State University / OhioLINK, 2008. http://rave.ohiolink.edu/etdc/view?acc_num=wright1216825497.

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Nishino, Noriko. "Mechanistic studies of atmospheric chemical reactions of hydroxyl radicals with aromatic hydrocarbons, including 2-ring polycyclic aromatic hydrocarbons, and terminal alkenes." Diss., UC access only, 2009. http://proquest.umi.com/pqdweb?index=94&did=1907248571&SrchMode=1&sid=1&Fmt=7&retrieveGroup=0&VType=PQD&VInst=PROD&RQT=309&VName=PQD&TS=1270251046&clientId=48051.

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Xu, Chao. "NMR structural studies of apolipoprotein E amino-terminal domain and amyloid beta peptide /." Available to subscribers only, 2006. http://proquest.umi.com/pqdweb?did=1136079871&sid=15&Fmt=2&clientId=1509&RQT=309&VName=PQD.

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Thesis (M.S.)--Southern Illinois University Carbondale, 2006.<br>"Department of Molecular Biology, Microbiology and Biochemisty." Includes bibliographical references (leaves 105-113). Also available online.

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Maya, Vladkova Georgieva. "TrkA COOH-terminal tail: its relevance on receptor stability and signaling for cell differentiation and survival." Doctoral thesis, Universitat de Lleida, 2010. http://hdl.handle.net/10803/8106.

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El receptor del factor de creixement nerviós TrkA contribueix a la supervivència i a la<br/>diferenciació de diferents poblacions neuronals. Tot i que les principals vies de senyalització i<br/>molècules adaptadores activades després de la unió del lligant al receptor estan ben<br/>estudiades, recentment un creixent nombre de proteïnes que interaccionen amb TrkA han<br/>estat descrites com a nous mecanismes de regulació del receptor. La trans-autofosforilació<br/>del receptor, a més d'activar les cascades de senyalització rellevants per la diferenciació i<br/>supervivència cel·lular, com són l

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El, Barbry Houssam. "Découverte du rôle crucial du résidu en position 2 des séquences MTS d’adressage mitochondrial." Electronic Thesis or Diss., Sorbonne université, 2023. http://www.theses.fr/2023SORUS035.

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Les mitochondries sont des organites complexes impliquant un millier de protéines, la plupart codées dans le génome nucléaire. Leur biogenèse a nécessité au cours de l’évolution la mise en place de systèmes efficaces d’adressage et d’import protéique, et des défaillances de ces systèmes sont associées à des pathologies graves, neuropathies, troubles cardiovasculaires, myopathies, maladies neurodégénératives ainsi que cancers. De nombreuses protéines mitochondriales possèdent en N-terminal une séquence d’adressage appelée MTS (Mitochondrial Targeting sequence) qui forme une hélice alpha amphiph

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NADAL, WOLLBOLD FLORENCE. "Activation et regulation des map kinases extracellular signal-regulated kinase 2 et c-jun nh2-terminal kinase 1 dans les plaquettes humaines." Paris 7, 2000. http://www.theses.fr/2000PA077163.

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Les map kinases sont des serine/threonine kinases regroupees en trois familles : les extracellular signal-regulated kinases (erks), les c-jun nh2-terminal kinases (jnks) et les p38 m a p k s. Principalement activees par les recepteurs a activite tyrosine kinase, les recepteurs couples aux proteines g heterotrimeriques et les integrines, elles jouent un role important dans la proliferation, la differenciation, la migration et l'apoptose. Si l'activation, la regulation, et le role des map kinases sont tres etudiees dans les cellules proliferatrices, tres peu de travaux sont realises dans les cel

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FODERA', Emanuele. "The peculiar processing of LRP8 and its significance for Alzheimer's disease." Doctoral thesis, Università degli studi del Molise, 2022. https://hdl.handle.net/11695/115827.

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La malattia di Alzheimer (AD) è la forma più comune di demenza e ad oggi non esiste una terapia efficace per guarire. L'ipotesi della cascata amiloide afferma che i peptidi β-amiloidi, derivanti dall’aberrante processing della Proteina Precursore dell’Amilode (o APP) da parte degli enzimi β- (BACE 1) e γ-secretasi, sono responsabili dell’amiloidosi, perdita neuronale e demenza. Oltre alle forme sporadiche, l' AD familiare è causata dalla iperespressione o mutazione nel gene APP, o da mutazioni nei geni delle Preseniline, componenti chiave del complesso enzimatico (γ-secretasi) che scinde APP.

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Möhwald, Jiří. "Ukázka řízení otáček motoru frekvenčním měničem." Master's thesis, Vysoké učení technické v Brně. Fakulta strojního inženýrství, 2009. http://www.nusl.cz/ntk/nusl-228651.

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The following diploma thesis deals with the management of asynchronous motor revolutions by a frequency converter MICROMASTER 440 via the programmable controller S7-200. At the beginning, I researched the company documentation of Siemens, which is the producer of the frequency converter and the programmable controller mentioned above. As my work proceeded, I also started to study the company documentation of Mitsubishi Electric, which produces the operating pannel. The first part of my thesis provides a general description of the stated devices and the second part deals with the solution of th

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Nagar, Bhushan. "X-ray crystallographic analysis of 1) the two N-terminal domains of epithelial cadherin and 2) C3d, a fragment of the complement protein C3." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 2001. http://www.collectionscanada.ca/obj/s4/f2/dsk3/ftp05/NQ63590.pdf.

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Price, Anna Helen. "Biomarkers for cardiovascular risk prediction in people with type 2 diabetes." Thesis, University of Edinburgh, 2017. http://hdl.handle.net/1842/28785.

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Introduction: Type 2 diabetes continues to be one of the most common non-communicable diseases worldwide and complications due to type 2 diabetes, such as cardiovascular disease (CVD) can cause severe disability and even death. Despite advances in the development and validation of cardiovascular risk scores, those used in clinical practice perform inadequately for people with type 2 diabetes. Research has suggested that particular non-traditional biomarkers and novel omics data may provide additional value to risk scores over-and-above traditional predictors. Aims: To determine whether a small

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Soumya, R. Deo. "Characterization of the terminal region RNAs of the West Nile virus genome and their interaction with the small isoform of 2' 5'-oligoadenylate synthetases (OAS)." Plos.org, 2014. http://hdl.handle.net/1993/30733.

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2'-5'-oligoadenylate synthetases (OAS) are interferon-stimulated proteins that act in the innate immune response to viral infection. Upon binding to viral double-stranded RNAs, OAS enzymes produce 2'-5'-linked oligoadenylates that stimulate RNase L and ultimately slow viral propagation. Studies have linked mutations in the OAS1 gene to increased susceptibility to West Nile virus (WNV) infection, highlighting the importance of the OAS1 enzyme. Here I report that the 5'-terminal region (5'-TR) of the WNV genome, comprising both the 5'-untranslated region (5'-UTR) and initial coding region, is ca

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Tjhen, Richard June. "Structure and dynamics of ribonucleoproteins by X-ray crystallography and NMR: Structural basis of Piwi PAZ domain binding preference for 2'-O-methylated 3' terminal ssRNAs." Diss., Search in ProQuest Dissertations & Theses. UC Only, 2010. http://gateway.proquest.com/openurl?url_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:dissertation&res_dat=xri:pqdiss&rft_dat=xri:pqdiss:3398888.

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Sperling, Adam Samuel Abdur-Rahim. "The function of the histone H3 N terminal tail in the formation of heterochromatin in the budding yest, Saccharomyces cerevisiae." Diss., Restricted to subscribing institutions, 2009. http://proquest.umi.com/pqdweb?did=1905641821&sid=1&Fmt=2&clientId=1564&RQT=309&VName=PQD.

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Maimari, Theopisti [Verfasser], Kristina [Gutachter] Lorenz, Andreas [Gutachter] Schlosser та Karoline [Gutachter] Kisker. "The influence of N-terminal peptides of G-protein coupled receptor kinase (GRK) 2, 3 and 5 on β-adrenergic signaling / Theopisti Maimari ; Gutachter: Kristina Lorenz, Andreas Schlosser, Karoline Kisker". Würzburg : Universität Würzburg, 2020. http://d-nb.info/1204006369/34.

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De, Loayza Tantalean Leonora Raquel, and Vasquez Milagros Del Pilar Esquen. "Calidad de vida de los pacientes con enfermedad renal crónica en estadio terminal por diabetes mellitus tipo 2 en terapia de reemplazo renal atendidos en un hospital de Essalud en el año 2018-2019." Bachelor's thesis, Universidad Católica Santo Toribio de Mogrovejo, 2021. http://hdl.handle.net/20.500.12423/3321.

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Objetivos: Describir la calidad de vida así como los factores sociodemográficos de pacientes en hemodiálisis y diálisis peritoneal por diabetes mellitus tipo 2. Metodología: Estudio descriptivo transversal. Se aplicó el instrumento SF-36 que evalúa la calidad de vida, y el cuestionario APEIM versión modificada 2011-2012 para evaluar el nivel socioeconómico a 59 pacientes con diagnóstico de enfermedad renal crónica terminal por diabetes mellitus tipo 2 en terapia dialítica, seleccionados según criterios de inclusión. Resultados: En hemodiálisis (HD) se incluyeron a 35 pacientes, de los cuales,

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Shasha, Adelle. "Metal-Catalysed Hydroamination." Science. School of Chemistry, 2007. http://hdl.handle.net/2123/1710.

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Doctor of Philosophy(PhD),<br>This thesis describes the synthesis of terminal and internal amino and amidoalkynes and their hydroamination (cyclisation) catalysed by the complex (bis(N-methylimidazol-2-yl)methane)dicarbonylrhodium(I) tetraphenylborate (1). A series of analogous palladium complexes were also prepared and investigated for catalytic hydroamination. The scope of the rhodium(I) complex (1) for the intramolecular hydroamination of more complex amino and amidoalkyne substrates was investigated. This was made possible with the synthesis of aliphatic substrates, namely, 4 pentyn 1

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Shasha, Adelle. "Metal-Catalysed Hydroamination." Thesis, The University of Sydney, 2006. http://hdl.handle.net/2123/1710.

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This thesis describes the synthesis of terminal and internal amino and amidoalkynes and their hydroamination (cyclisation) catalysed by the complex (bis(N-methylimidazol-2-yl)methane)dicarbonylrhodium(I) tetraphenylborate (1). A series of analogous palladium complexes were also prepared and investigated for catalytic hydroamination. The scope of the rhodium(I) complex (1) for the intramolecular hydroamination of more complex amino and amidoalkyne substrates was investigated. This was made possible with the synthesis of aliphatic substrates, namely, 4 pentyn 1 amide (3) and 5 hexyn 1 ami

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FU, TZU-HSIU, and 傅子修. "Satisfaction Analysis of Airport Terminal Sign System – A Case of Taoyuan International Airport Terminal 2." Thesis, 2019. http://ndltd.ncl.edu.tw/handle/6f84vf.

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碩士<br>開南大學<br>觀光運輸學院碩士在職專班<br>107<br>Summary Symbols and signs have become an indispensable facility for human life and activities, especially at the Taoyuan International Airport, where most of the country's main entrances and exits are available. High dependence to assist in quickly finding directions during the immigration process. The goodness of the marking system not only makes passengers more convenient, but also an important indicator of the level of airport service. This study studies the satisfaction of the exit marking system of the second terminal of Taoyuan International Airport,

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