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Artykuły w czasopismach na temat „Toxicologie – Optique”

Autor: Grafiati

Data publikacji: 15 lutego 2025

Data aktualizacji: 31 lipca 2025

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1

Gautam, Nawaraj. "Food Colorants and their Toxicology: An Overview." Sunsari Technical College Journal 2, no. 1 (2016): 69–75. http://dx.doi.org/10.3126/stcj.v2i1.14803.

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There are many kinds of colorants, which have been already banned or are used under strict supervision of food safety authorities. Use of artificial colorants over natural ones has increased in modern world. Besides, it has also concerned on importance of toxicological studies. Acceptable daily intake (ADI) of different colorants will define the optimum level of coloring substances on food items. Molecular size of coloring agents and their absorption ratio have significant role in toxico-kinetics. Bigger molecular size has lower absorption capacity and toxicity while vice versa for the smaller

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2

Chinyere, Eleanya,, Igboanugo, Uchechukwu, Dibua, Nwamaka Anthonia, et al. "Dough Rising Capacity of a Novel Yeast Yarrowia Phangngaensis Isolated from Palmwine as Bakery Yeast Option." International Journal of Research and Innovation in Applied Science X, no. V (2025): 808–23. https://doi.org/10.51584/ijrias.2025.100500074.

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The ability of yeast rise dough, enhance texture and sensory properties are highly valued by bakers. The aim of this study was to evaluate dough rising capacity of a novel yeast Yarrowia phangngaensis isolated from palmwine as bakery yeast option. Palmwine samples were collected from different parts of Anambra State. Thirty-five yeast isolate were screened for bakery yeast potentials, selected yeasts were subjected to stress tolerance, optimization of cultural conditions, pathogenicity test, dough leavening capacity, sensory evaluation and toxicology study. The results show that the most suita

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3

Charlebois, Denis, Konka Veeranjaneyulu, and Roger M. Leblanc. "Étude de l’activité photosynthétique à l’aide de la spectroscopic photoacoustique: applications potentielles en écotoxicologie." Water Quality Research Journal 28, no. 4 (1993): 743–56. http://dx.doi.org/10.2166/wqrj.1993.040.

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Résumé La spectroscopic photoacoustique permet la détection de la chaleur émise lors de désactivations thermiques suite à l’absorption, par un échantillon, de la lumière monochromatique modulée. En faisant varier la longueur d’onde du faisceau d’analyse, nous obtenons un spectre comparable à celui obtenu par la spectroscopic d’absorption. La spectroscopic photoacoustique possède l’avantage d’être applicable aux échantillons dont les propriétés optiques ne se prêtent pas aux techniques spectroscopiques conventionnelles, par exemple dans le cas des algues unicellulaires. Cette technique permet,

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4

Betton, G., A. Cockburn, E. Harpur, et al. "A Critical Review of the Optimum Duration of Chronic Rodent Testing for the Determination of Non-Tumourigenic Toxic Potential: A Report by the BTS Working Party on Duration of Toxicity Testing." Human & Experimental Toxicology 13, no. 4 (1994): 221–32. http://dx.doi.org/10.1177/096032719401300401.

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This review indicates that for the detection of non-neoplastic toxic effects: 1 Four decades of accumulated literature provide no lead as to the optimum duration of repeat dose toxicity testing required for all classes of chemicals, although 6 months repeated administration appears adequate for pharmaceuticals. 2 Three month studies predicted the 2 year outcome for 70% of the compounds evaluated in this pilot study using data published by the US National Toxicology Program. 3 In spite of the limitations of this pilot study, this finding is considered encouraging as it is close to that generate

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5

Muhammad Qasim Memon, Rabail Altaf, Pardeep Kumar, Abrar Ul Hasnain Memon, Haya Afzal Memon, and Sultan Rajper. "The most optimum imaging modality for diagnosis of shajjah hurt in medicolegal cases of head injuries." Professional Medical Journal 30, no. 01 (2023): 118–23. http://dx.doi.org/10.29309/tpmj/2023.30.01.7122.

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Objective: To compare the optimum imaging modality to assess the various kinds of Shajjah hurt in MLE cases of head injuries. Study Design: Cross-sectional study. Setting: Department of Forensic Medicine and Toxicology at Gambat Medical College at Pir Abdul Qadir Shah Jeelani Institute of Medical Sciences, GAMBAT. Period: March 2021 to February 2022. Material & Methods: Medicolegal cases of head injuries of all age groups (infant to old) and of either gender presented to the Emergency department for treatment and medicolegal certification were included. 164 medicolegal cases of moderate to

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6

White, S. L., and D. M. Hoover. "Effects of long-term exposure to modified Karnovsky’s fixative on tissue ultrastructure." Proceedings, annual meeting, Electron Microscopy Society of America 48, no. 3 (1990): 806–7. http://dx.doi.org/10.1017/s042482010016159x.

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In toxicology studies, the potential to store tissues in the primary fixative offers the flexibility to collect selected specimens and hold them for further processing contingent upon findings in other areas such as histopathology and biochemistry. This would allow conservation of resources and time by eliminating the need to duplicate studies specifically for electron microscopy. Previous investigators have dealt primarily with the morphological effects on the tissue produced by various fixatives, buffers, and osmolalities while using optimum processing schedules. However, little information

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7

Krokos, Adamantios, Elisavet Tsakelidou, Eleni Michopoulou, Nikolaos Raikos, Georgios Theodoridis, and Helen Gika. "NSAIDs Determination in Human Serum by GC-MS." Separations 5, no. 3 (2018): 37. http://dx.doi.org/10.3390/separations5030037.

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Non-steroidal anti-inflammatory drugs (NSAIDs) are being widely consumed without medical prescription and are often the cause of intoxication, usually in young children. For this, there is a special need in their determination in routine toxicology analysis. As screening methods mainly focus on drugs of abuse (DOA) that are alkaline compounds in their majority, they are not optimized for acidic drugs, such as NSAIDs. Thus, more specific methods are needed for the detection and quantification of this class of drugs. In this study, the efficient extraction of NSAIDs from blood serum and their ac

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8

Norheim, Gunnar. "AN APPROACH TO THE PROBLEM OF OPTIMUM SELENIUM INTAKE IN MAN." Acta Pharmacologica et Toxicologica 59 (March 13, 2009): 177. http://dx.doi.org/10.1111/j.1600-0773.1986.tb02737.x.

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9

Scarpitta, S. Charles. "Optimum 222Rn-adsorbing Activated Charcoals." Health Physics 62, no. 6 (1992): 576–80. http://dx.doi.org/10.1097/00004032-199206000-00013.

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10

Xiong, Lu, Mengxue Peng, Meng Zhao, and Zhihong Liang. "Truncated Expression of a Carboxypeptidase A from Bovine Improves Its Enzymatic Properties and Detoxification Efficiency of Ochratoxin A." Toxins 12, no. 11 (2020): 680. http://dx.doi.org/10.3390/toxins12110680.

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Ochratoxin A (OTA) is a toxic secondary metabolite produced mainly by Penicillium spp. and Aspergillus spp. and commonly found in foodstuffs and feedstuffs. Carboxypeptidase A (CPA) can hydrolyze OTA into the non-toxic product ochratoxin α, with great potential to realize industrialized production and detoxify OTA in contaminated foods and feeds. This study constructed a P. pastoris expression vector of mature CPA (M-CPA) without propeptide and signal peptide. The results showed that the degradation rate of OTA by M-CPA was up to 93.36%. Its optimum pH was 8, the optimum temperature was 40 °C,

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11

Joksić, Gordana, Mileva Mićić, Jelena Filipović, et al. "Cell proliferation assay – method optimisation for in vivo labeling of DNA in the rat forestomach." Acta Veterinaria 67, no. 1 (2017): 1–10. http://dx.doi.org/10.1515/acve-2017-0001.

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AbstractThe study of cell proliferation is a useful tool in the fields of toxicology, pathophysiology and pharmacology. Cell proliferation and its degree can be evaluated using 5-bromo-2′-deoxyuridine which is incorporated into the newly synthesized DNA. The aim of this study was the optimization of subcutaneous application of 5-bromo-2′-deoxyuridine implantation for continuous and persistent marking of proliferating cells in the rat forestomach. 3-tert-Butyl-4-hydroxyanisole was used as the agent that ensures cell proliferation. In order to determine the optimal dose for proliferating cells l

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12

Kong, Qing, Cuiping Zhai, Bin Guan, Chunjuan Li, Shihua Shan, and Jiujiang Yu. "Mathematic Modeling for Optimum Conditions on Aflatoxin B1 Degradation by the Aerobic Bacterium Rhodococcus erythropolis." Toxins 4, no. 11 (2012): 1181–95. http://dx.doi.org/10.3390/toxins4111181.

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13

Shukla, Sanjay K., Tonia C. Carter, Zhan Ye, Madhulatha Pantrangi, and Warren E. Rose. "Modeling of Effective Antimicrobials to Reduce Staphylococcus aureus Virulence Gene Expression Using a Two-Compartment Hollow Fiber Infection Model." Toxins 12, no. 2 (2020): 69. http://dx.doi.org/10.3390/toxins12020069.

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Toxins produced by community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) contribute to virulence. We developed a statistical approach to determine an optimum sequence of antimicrobials to treat CA-MRSA infections based on an antimicrobial’s ability to reduce virulence. In an in vitro pharmacodynamic hollow fiber model, expression of six virulence genes (lukSF-PV, sek, seq, ssl8, ear, and lpl10) in CA-MRSA USA300 was measured by RT-PCR at six time points with or without human-simulated, pharmacokinetic dosing of five antimicrobials (clindamycin, minocycline, vancomycin, lin

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14

Addante-Moya, Luis G., Antonio Abad-Somovilla, Antonio Abad-Fuentes, Consuelo Agulló, and Josep V. Mercader. "Assessment of the Optimum Linker Tethering Site of Alternariol Haptens for Antibody Generation and Immunoassay Development." Toxins 13, no. 12 (2021): 883. http://dx.doi.org/10.3390/toxins13120883.

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Immunochemical methods for mycotoxin analysis require antigens with well-defined structures and antibodies with outstanding binding properties. Immunoreagents for the mycotoxins alternariol and/or alternariol monomethyl ether have typically been obtained with chemically uncharacterized haptens, and antigen conjugates have most likely been prepared with mixtures of functionalized molecules. For the first time, total synthesis was performed, in the present study, to obtain two haptens with opposite linker attachment locations. The functionalized synthetic haptens were purified and deeply charact

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15

Bonneau, D., V. Thybaud, C. Melcion, F. Bouhet, and A. Cordier. "Optimum associations of tester strains for maximum detection of mutagenic compounds in the Ames test." Mutation Research/Environmental Mutagenesis and Related Subjects 252, no. 3 (1991): 269–79. http://dx.doi.org/10.1016/0165-1161(91)90006-t.

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Collins, Thomas F. X., Thomas N. Black, Stuart L. Graham, Benjamin A. Jackson, and John J. Welsh. "Updating Developmental Toxicity Testing Guidelines for the Safety Assessment of Direct Food Additives and Color Additives Used in Food: Results of a Survey." Journal of the American College of Toxicology 10, no. 4 (1991): 461–75. http://dx.doi.org/10.3109/10915819109078643.

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In 1982, the Food and Drug Administration (FDA) issued guidelines for testing the effects of direct food additives and color additives on developing embryos and for longer monitoring during several generations. In 1984, an FDA task force began a review of testing procedures for reproductive and developmental toxicity. The Developmental Toxicity Committee was formed specifically to evaluate the current guidelines and to propose revisions. As part of the evaluation, a two-part questionnaire was devised and sent to about 800 members of the Teratology Society and the Reproductive and Developmental

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17

Jalani, Raihan Izzatie, Raihana Edros, and Shuhada A. Mutallib. "Optimisation of Characteristics of CHI-ALG-CaCl<sub>2</sub> Nanocarriers Loaded with Non-Volatile Extracts of <i>Cymbopogon</i> <i>Sp.</i>." Materials Science Forum 1056 (March 14, 2022): 167–72. http://dx.doi.org/10.4028/p-34734y.

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Nanotechnology is receiving an intense attention these days due to its potential application in various fields including cosmeceutical and pharmaceutical. Nanoparticles encapsulating natural extract are usually characterised for their particle size and polydispersity index but zeta potential is hardly discussed. The zeta potential is the measurement that shows the aggregation behaviour, reactivity and toxicology. In this study, nanoparticle encapsulating Cymbopogon sp. have been formulated to develop a cosmeceutical product. The antioxidant properties from aqueous extract of Cymbopogon sp. was

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18

Yoon, Jung-Hwan, Yong Geon Shin, Hyuck Soo Kim, M. B. Kirkham, and Jae E. Yang. "Screening of a Novel Solvent for Optimum Extraction of Anionic Surfactants in Water." Toxics 10, no. 2 (2022): 80. http://dx.doi.org/10.3390/toxics10020080.

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Anionic surfactants (AS) are detrimental aquatic pollutants due to their well-characterized toxicity to aquatic organisms. The concentration of AS in aquatic environments is increasing because of their extensive use in many industries and households. The standard reference method for AS analysis is to determine a methylene blue active substance (MBAS) complex formed between AS and the methylene blue (MB) cation by using chloroform. However, chloroform has a low AS extraction efficiency and other limiting properties, such as a high density and volatility, which make the conventional AS analytic

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19

AOYAMA, KAN, NAOKI YAMADA, MASUO YAMADA, and NORIKATSU HAMAMURA. "Studies on earthy-musty odor in natural water. II. Optimum pH for earthy-musty odor substances production of actinomycetes." Eisei kagaku 32, no. 2 (1986): 85–90. http://dx.doi.org/10.1248/jhs1956.32.85.

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Zhao, Qi, Claudia Wigmann, Ashtyn Tracey Areal, Hicran Altug, and Tamara Schikowski. "Effect of non-optimum ambient temperature on cognitive function of elderly women in Germany." Environmental Pollution 285 (September 2021): 117474. http://dx.doi.org/10.1016/j.envpol.2021.117474.

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Annisa Indriyani, Nenden Indriyani Anggraeni, Sriwidodo, and Iman Permana Maksum. "Optimization extracellular secretion of Recombinant Human Epidermal Growth Factor (hEGF) in Escherichia coli BL21 (DE3) pD881-OmpA-hEGF by using Response Surface Method (RSM)." International Journal of Research in Pharmaceutical Sciences 10, no. 3 (2019): 1824–31. http://dx.doi.org/10.26452/ijrps.v10i3.1378.

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Human Epidermal Growth Factor is techno-economically protein that has the function for stimulates a process of proliferation and cell differentiation. Because of that function, it can be a candidate for wound healing in ulcer diabetic. In the previous study, hEGF can extracellular secreted by OmpA signal peptide using recombinant DNA. The production method of recombinant hEGF will be extracellular secreted by Escherichia coli. However, the optimum secretion of OmpA has not been studied. Therefore the purpose of this study is to determine the optimum conditions using the RSM method. This resear

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22

Ramya Ramachandran, Kanika Bhatnagar, Ramlal Thakur, and Utpal Roy. "The preliminary optimization of culture components for improving antifungal production by a wild-type soil bacteria Bacillus subtilis." International Journal of Research in Pharmaceutical Sciences 11, SPL4 (2020): 955–61. http://dx.doi.org/10.26452/ijrps.v11ispl4.4229.

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Antifungal compounds are produced by Bacillus species under various growth conditions. While optimizing the antifungal production by using the one-factor-at-a-time (OFAT) and response surface methodology (RSM) approaches mannose and malt extract were identified as the most suitable carbon and nitrogen sources respectively. The RSM was applied to determine the optimum conditions of the three parameters such as pH, carbon and nitrogen sources for improved production. Optimum concentrations of carbon and nitrogen sources were 0.3% and 0.6% respectively with optimum media pH of 7.0 which showed op

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23

Halim, A. A., M. M. Hanafiah, M. Asmi, and Z. Daud. "Boron removal from aqueous solution using coagulation- flocculation with curcumin : A response surface methodology." Journal of Environmental Biology 42, no. 3(SI) (2021): 750–55. http://dx.doi.org/10.22438/jeb/42/3(si)/jeb-03.

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Aim: Application of response surface methodology (RSM) to determine optimum parameters in the coagulation-flocculation process aided by curcumin for boron removal from aqueous solution was investigated. Methodology: Different parameters such as pH, coagulant dosage, and curcumin dosage that effect boron removal were tested. Application of central composite design in RSM was used to design the coagulation-flocculation experiment. Results: The results showed 75% of boron removal, while the optimum parameters for boron removal were observed at pH 2.8, 132.05 ppm poly aluminum chloride dose and 11

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24

Shokri, Rouhollah, Reza Jalilzadeh Yengejeh, Ali Akbar Babaei, Ehsan Derikvand, and Ali Almasi. "UV activation of hydrogen peroxide for removal of azithromycin antibiotic from aqueous solution: determination of optimum conditions by response surface methodology." Toxin Reviews 39, no. 3 (2019): 284–91. http://dx.doi.org/10.1080/15569543.2018.1517803.

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Xiong, Dongwei, Jun Wen, Gen Lu, Tianxi Li, and Miao Long. "Isolation, Purification, and Characterization of a Laccase-Degrading Aflatoxin B1 from Bacillus amyloliquefaciens B10." Toxins 14, no. 4 (2022): 250. http://dx.doi.org/10.3390/toxins14040250.

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Aflatoxins, widely found in feed and foodstuffs, are potentially harmful to human and animal health because of their high toxicity. In this study, a strain of Bacillus amyloliquefaciens B10 with a strong ability to degrade aflatoxin B1 (AFB1) was screened; it could degrade 2.5 μg/mL of AFB1 within 96 h. The active substances of Bacillus amyloliquefaciens B10 for the degradation of AFB1 mainly existed in the culture supernatant. A new laccase with AFB1-degrading activity was separated by ammonium sulfate precipitation, diethylaminoethyl (DEAE) and gel filtration chromatography. The results of m

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26

Donnelly, Rossa, Christopher Elliott, Guangtao Zhang, Bob Baker, and Julie Meneely. "Understanding Current Methods for Sampling of Aflatoxins in Corn and to Generate a Best Practice Framework." Toxins 14, no. 12 (2022): 819. http://dx.doi.org/10.3390/toxins14120819.

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Aflatoxin contamination in corn is a significant issue, posing substantial health threats to humans and animals. Aflatoxin testing protects consumer health, ensures the safe global trade of corn, and verifies compliance with legislation; however, effective sampling procedures are essential to ensure reliable results. While many sampling procedures exist, there is no evidence to indicate which is the best approach to ensure accurate detection. Using scientific and gray literature sources, this review analyzed sampling procedures to determine an optimum approach to guide the development of stand

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Aytekin, Kürşad, Murat Uysal, Göksel Gültekin Şahiner, et al. "Evaluation of different intraarticular injection volumes to assess optimum efficient amount; an experimental study in rat knee joints." Journal of Pharmacological and Toxicological Methods 101 (January 2020): 106658. http://dx.doi.org/10.1016/j.vascn.2019.106658.

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Abd-Elsalam, MA, N. Abdoon, and MS Al-Ahaidib. "What is the optimum concentration of m-cresol in antivenoms?" Journal of Venomous Animals and Toxins including Tropical Diseases 17, no. 1 (2011): 12–22. http://dx.doi.org/10.1590/s1678-91992011000100003.

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BOUCHAREINE, Patrick. "Spectrométrie optique." Mesures mécaniques et dimensionnelles, October 1994. http://dx.doi.org/10.51257/a-v1-r6310.

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HAWKES, Peter. "Optique électronique." Électronique, June 1993. http://dx.doi.org/10.51257/a-v1-e1300.

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CABANNES, François. "Pyrométrie optique." Mesures physiques, July 1990. http://dx.doi.org/10.51257/a-v1-r2610.

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HENRY, Michel. "Activité optique." Mesures mécaniques et dimensionnelles, April 1991. http://dx.doi.org/10.51257/a-v1-r6470.

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BONJOUR, Pierre. "Optique électronique." Électronique, December 1986. http://dx.doi.org/10.51257/a-v2-e2160.

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SAPRIEL, Jacques. "Acousto-optique." Électronique, September 1995. http://dx.doi.org/10.51257/a-v1-e1955.

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ARNOLD, Michel. "Microscopie optique." Techniques d'analyse, October 1993. http://dx.doi.org/10.51257/a-v1-p860.

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PELTIÉ, Philippe. "Traitement optique du signal." Électronique, December 1985. http://dx.doi.org/10.51257/a-v2-e1250.

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LEDOUX, Isabelle. "Optique non linéaire quadratique." Optique Photonique, February 1997. http://dx.doi.org/10.51257/a-v1-e1965.

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BILLIEN, Pierre. "Lecture optique de caractères." Technologies logicielles Architectures des systèmes, June 1985. http://dx.doi.org/10.51257/a-v1-h1412.

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RÉMY, Claire. "Lecture optique de caractères." Traçabilité, March 1992. http://dx.doi.org/10.51257/a-v2-h1405.

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CASTÉRA, Jean-Paul. "Applications de la magnéto-optique." Électronique, November 1997. http://dx.doi.org/10.51257/a-v1-e1962.

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VAN LABEKE, Daniel. "Microscopie optique en champ proche." Techniques d'analyse, March 1998. http://dx.doi.org/10.51257/a-v1-p862.

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FERRE, Jacques. "Application de la magnéto-optique." Électronique, April 2016. http://dx.doi.org/10.51257/a-v2-e1962.

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RADIX, Jean-Claude. "Gyromètres optiques." Mesures mécaniques et dimensionnelles, September 1999. http://dx.doi.org/10.51257/a-v2-r1945.

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PEZ, Mathias. "Interconnexions optiques." Optique Photonique, November 2001. http://dx.doi.org/10.51257/a-v1-e3652.

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PROST, Bernard. "Disques optiques." Électronique, March 1995. http://dx.doi.org/10.51257/a-v2-e5450.

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AUGUSTE, Jean-Louis, Jean-Marc BLONDY, and Philippe ROY. "La fibre optique microstructurée air-silice." Mesures mécaniques et dimensionnelles, June 2005. http://dx.doi.org/10.51257/a-v1-re43.

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PEPING, Jacques. "Périphériques de stockage magnétique et optique." Technologies logicielles Architectures des systèmes, August 1997. http://dx.doi.org/10.51257/a-v1-h1258.

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BOULON, Georges. "Cristaux et optique laser non linéaires." Physique Chimie, January 2006. http://dx.doi.org/10.51257/a-v1-af3278.

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JOINDOT, Michel, and Irène JOINDOT. "Systèmes de transmission sur fibre optique." Optique Photonique, August 1999. http://dx.doi.org/10.51257/a-v1-te7115.

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Lethien, Christophe, and Christophe Loyez. "Fibres optiques multimodales." Optique Photonique, August 2010. http://dx.doi.org/10.51257/a-v1-e3600.

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