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1

Bayissa, Yared, Tsegaye Tadesse, and Getachew Demisse. "Building A High-Resolution Vegetation Outlook Model to Monitor Agricultural Drought for the Upper Blue Nile Basin, Ethiopia." Remote Sensing 11, no. 4 (2019): 371. http://dx.doi.org/10.3390/rs11040371.

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To reduce the impacts of drought, developing an integrated drought monitoring tool and early warning system is crucial and more effective than the crisis management approach that is commonly used in developing countries like Ethiopia. The overarching goal of this study was to develop a higher-spatial-resolution vegetation outlook (VegOut-UBN) model that integrates multiple satellite, climatic, and biophysical input variables for the Upper Blue Nile (UBN) basin. VegOut-UBN uses current and historical observations in predicting the vegetation condition at multiple leading time steps of 1, 3, 6,
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2

Darudiato, Suparto. "Sistem Informasi Pengendalian Kualitas Sarana Penunjang Operasi UPT Perangkat Lunak." Generic 14, no. 2 (2022): 63–69. http://dx.doi.org/10.18495/generic.v14i2.133.

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Dalam mendukung proses pembelajaran, UBN mempunyai sebuah unit yang dikenal dengan Unit Penyedia Teknis yang disingkat menjadi UPT Perangkat Lunak. Unit ini merupakan sebuah unit kerja yang bertugas untuk melaksanakan kegiatan perkuliah matakuliah praktikum khusus perangkat lunak. Mengingat tugas dan tanggung jawabnya, maka UPT Perangkat Lunak UBM berkewajiban untuk menjamin terlaksananya praktikum dengan baik dan sesuai dengan standar yang sudah ditentukan. Untuk menjawab standar yang sudah ditentukan tersebut, diperlukan sistem informasi yang mampu menyajikan informasi untuk mengendalikan ku
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3

Kattah, Jorge C., Ali Saber Tehrani, Sascha du Lac, David E. Newman-Toker, and David S. Zee. "Conversion of upbeat to downbeat nystagmus in Wernicke encephalopathy." Neurology 91, no. 17 (2018): 790–96. http://dx.doi.org/10.1212/wnl.0000000000006385.

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ObjectiveTo explain (1) why an initial upbeat nystagmus (UBN) converts to a permanent downbeat nystagmus (DBN) in Wernicke encephalopathy (WE) and (2) why convergence and certain vestibular provocative maneuvers may transiently switch UBN to DBN.MethodsFollowing a literature review and study of our 2 patients, we develop hypotheses for the unusual patterns of vertical nystagmus in WE.ResultsOur overarching hypothesis is that there is a selective vulnerability and a selective recovery from thiamine deficiency of neurons within brainstem gaze-holding networks. Furthermore, since the circuits aff
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4

G., Prasanna Kumar, and Shankaraiah N. "An Efficient IoT-based Ubiquitous Networking Service for Smart Cities Using Machine Learning Based Regression Algorithm." International Journal of Information Technology and Computer Science 15, no. 3 (2023): 15–25. http://dx.doi.org/10.5815/ijitcs.2023.03.02.

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In recent days, the smart city project has been emerging concept all over the world. In this process, the proper communication between the sensors and the smart devices, and identification of optimal path between sensors and mutation sensors in large geographical area is very difficult. The main objective has been considered to overcome the drawbacks as mentioned above. The proposed algorithm is efficient to provide integrated communication of IoT-based ubiquitous networking (UBN) devices to improve in large geographically distributed area. The data storage capacity and accuracy of sensors and
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5

McTaggart-Cowan, Ron, Claude Girard, André Plante, and Michel Desgagné. "The Utility of Upper-Boundary Nesting in NWP." Monthly Weather Review 139, no. 7 (2011): 2117–44. http://dx.doi.org/10.1175/2010mwr3633.1.

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Abstract The importance of stratospheric influences for medium-range numerical weather prediction (NWP) of the troposphere has led to increases in the heights of global model domains at operational centers around the world. Grids now routinely extend to 0.1 hPa (approximately 65 km) in these systems, thereby covering the full depth of the stratosphere and the lower portion of the mesosphere. Increasing the vertical extent of higher-resolution limited-area models (LAMs) nested within the global forecasts is problematic because of the computational cost of additional levels and the possibility o
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6

Tumas, Natalia, María Eugenia Peisino, Alicia Díaz, and Gabriel Esteban Acevedo. "Distribución temporo-espacial de la mortalidad infantil, y su relación con determinantes sociales contextuales en la ciudad de Córdoba, Argentina." Revista de Salud Pública 25, no. 1 (2021): 21–31. http://dx.doi.org/10.31052/1853.1180.v25.n1.31157.

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Aim: to characterize the temporal distribution of infant mortality rates (IMR) in the 2009-2018 decade, and to analyze the socio-spatial distribution of IMR and its relation with contextual social determinants in the triennium 2015-2017, in Cordoba city (Argentina). Methods: a time trend (2009-2018) and a multiple groups ecological study (2015-2017) (n= 99 programmatic areas -PA-) was carried out. Data on IMR and social indicators were obtained from secondary data sources. The temporal evolution of IMRs, and the spatial distribution of IMRs and the proportion of households with unsatisfied bas
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7

Cabrera-Barona, Pablo F., Gualdemar Jimenez, and Pablo Melo. "Types of Crime, Poverty, Population Density and Presence of Police in the Metropolitan District of Quito." ISPRS International Journal of Geo-Information 8, no. 12 (2019): 558. http://dx.doi.org/10.3390/ijgi8120558.

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This exploratory study identifies spatial patterns of crimes and their associations with the index of Unsatisfied Basic Needs (UBN), with Communitarian Policy Units (CPU) density, as well as with population density. The case study is the Metropolitan District of Quito. Correlation analyses were applied between number of registers of each type of crime, and the UBN index, CPU density and population density measures. The spatial autocorrelation index of Getis-Ord Gi* was calculated to identify hotspots of the different types of crime. Ordinary least squares regressions and geographically weighte
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8

Taye, Mintesinot, Dejene Sahlu, Benjamin F. Zaitchik, and Mulugeta Neka. "Evaluation of Satellite Rainfall Estimates for Meteorological Drought Analysis over the Upper Blue Nile Basin, Ethiopia." Geosciences 10, no. 9 (2020): 352. http://dx.doi.org/10.3390/geosciences10090352.

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The objective of this study was to evaluate the performance of satellite rainfall estimates (Climate Hazards Group Infrared Precipitation with Stations version 2 (CHIRPSv2) and Multi-Source Weighted-Ensemble Precipitation version 2 (MSWEPv2) from 1981 to 2018 for monthly meteorological drought analysis over the Upper Blue Nile (UBN) basin. The reference for the performance evaluation was rainfall measured in situ selected with reference to the elevation zones of the basin: Highland, midland, and lowland. Both the measured and estimated rainfall datasets were aggregated by month at a spatial re
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9

Teferi, E., S. Uhlenbrook, and W. Bewket. "Inter-annual and seasonal trends of vegetation condition in the Upper Blue Nile (Abbay) basin: dual scale time series analysis." Earth System Dynamics Discussions 6, no. 1 (2015): 169–216. http://dx.doi.org/10.5194/esdd-6-169-2015.

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Abstract. A long-term decline in ecosystem functioning and productivity, often called land degradation, is a serious environmental and development challenge to Ethiopia that needs to be understood so as to develop sustainable land use strategies. This study examines inter-annual and seasonal trends of vegetation cover in the Upper Blue Nile (UBN) or Abbay basin. Advanced Very High Resolution Radiometer (AVHRR) based Global Inventory, Monitoring, and Modelling Studies (GIMMS) Normalized Difference Vegetation Index (NDVI) was used for course scale long-term vegetation trend analysis. Moderate-re
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10

Rao, K. Bramareswara, SR Krishna Motukuri, K. Arun Kumar, CHVN Praveen Babu, and Vaibhav Pathak. "Pearl Millet Blast Pathogen Virulence Study and Identification of Resistance Donors on Virulent Isolate." Journal of Pure and Applied Microbiology 15, no. 2 (2021): 752–58. http://dx.doi.org/10.22207/jpam.15.2.27.

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Pearl Millet leaf Blast caused by Pyricularia grisea [teleomorph: Magnaporthe grisea], is spreading at an alarming rate in the major Pearl millet growing geographies of India effecting grain yield and green fodder yield. Blast isolates collected from Jaipur, Alwar and Toopran regions of India and virulence study conducted to identify the most virulent isolate among the three isolates. Artificial screening for Blast conducted on a raised bed method utilising uniform Blast Nursery (UBN) method. Eleven Pearl Millet genotypes (ICMB01333, ICMB03444, ICMB03555, ICMB06111, ICMB95444, ICMB11666, ICMB1
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11

Pietto, Marcos Luis, Federico Giovannetti, María Soledad Segretin, Sebastián Javier Lipina, and Juan Esteban Kamienkowski. "EEG Dynamics of Error Processing and Associated Behavioral Adjustments in Preschool Children." Brain Sciences 13, no. 4 (2023): 575. http://dx.doi.org/10.3390/brainsci13040575.

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Preschool children show neural responses and make behavioral adjustments immediately following an error. However, there is a lack of evidence regarding how neural responses to error predict subsequent behavioral adjustments during childhood. The aim of our study was to explore the neural dynamics of error processing and associated behavioral adjustments in preschool children from unsatisfied basic needs (UBN) homes. Using EEG recordings during a go/no-go task, we examined within-subject associations between the error-related negativity (ERN), frontal theta power, post-error slowing, and post-e
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12

Akawka, Ashenafi Lekasa, Alemseged Tamiru Haile, and Demelash Wondimagegnehu Goshime. "Regionalization of Conceptual Rainfall-Runoff Model Parameters for Predicting Stream Flows of Ungauged Catchments in the Upper Blue Nile Basin." Ethiopian Journal of Water Science and Technology 2 (December 26, 2019): 59–79. http://dx.doi.org/10.59122/1352681.

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Water resources development and research significantly suffered from lack of stream low data. Regionalization of model parameters was found veryuseful in filling such data gaps. We therefore regionalized the parameters of the HBV model so that the model could be used in ungauged catchments ofthe Upper Blue Nile (UBN) basin. Although we collected stream flow data for 76 stations from the Ministry of Water, Irrigation and Electricity, our dataquality assessment indicated that only 20 stations were suitable for calibrating the HBV model. We calibrated the model using hydro-climate data of 6 years
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13

Ossa González, Genjis Alberto. "Analysis of financial disparities in municipalities of the department of Cesar, Colombia: a longitudinal study (2019–2023)." Tendencias 26, no. 2 (2025): 241–71. https://doi.org/10.22267/rtend.252602.282.

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Introduction: This study analyzes the evolution of public revenues and expenditures in eight municipalities of the department of Cesar, Colombia, between 2019 and 2023, paying special attention to local fiscal dynamics and their relationship with social indicators such as Unsatisfied Basic Needs (UBN). Objective: To analyze financial disparities in municipalities in the department of Cesar. Methodology: A descriptive-comparative approach was applied based on the analysis of budget and population data. The sources of income and the destinations of expenditure in each municipality were observed
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14

Teferi, E., S. Uhlenbrook, and W. Bewket. "Inter-annual and seasonal trends of vegetation condition in the Upper Blue Nile (Abay) Basin: dual-scale time series analysis." Earth System Dynamics 6, no. 2 (2015): 617–36. http://dx.doi.org/10.5194/esd-6-617-2015.

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Abstract. A long-term decline in ecosystem functioning and productivity, often called land degradation, is a serious environmental challenge to Ethiopia that needs to be understood so as to develop sustainable land use strategies. This study examines inter-annual and seasonal trends of vegetation cover in the Upper Blue Nile (UBN) or Abbay Basin. The Advanced Very High Resolution Radiometer (AVHRR)-based Global Inventory, Monitoring, and Modeling Studies (GIMMS) normalized difference vegetation index (NDVI) was used for long-term vegetation trend analysis at low spatial resolution. Moderate Re
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15

Wang, Min, Peng Yang, and Yining Yang. "Carlitz’s Equations on Generalized Fibonacci Numbers." Symmetry 14, no. 4 (2022): 764. http://dx.doi.org/10.3390/sym14040764.

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Carlitz solved some Diophantine equations on Fibonacci or Lucas numbers. We extend his results to the sequence of generalized Fibonacci and Lucas numbers. In this paper, we solve the Diophantine equations of the form An1⋯Ank=Bm1⋯BmrCt1⋯Cts, where (An), (Bm), and (Ct) are generalized Fibonacci or Lucas numbers. Especially, we also find all solutions of symmetric Diophantine equations Ua1Ua2⋯Uam=Ub1Ub2⋯Ubn, where 1<a1≤a2≤⋯≤am, and 1<b1≤b2≤⋯≤bn.
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16

Isti Puspitasari, Erviyanti Rosmaida, and Taufiqurrohman Syahruri. "Pertanggungjawaban Hukum Ultimate Beneficiary Owner (UBN) yang Melakukan Gratifikasi Terhadap Pejabat." Jurnal Relasi Publik 2, no. 1 (2023): 1–17. https://doi.org/10.59581/jrp-widyakarya.v2i1.2018.

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Decision Number 2205 K/Pd/Sus/2022 The Supreme Court again upheld the acquittal decision of Samin Tan as the owner of PT Beneficial Ownershiprneo Lumbung Energi & Metal (PT BLEM). The panel is of the opinion that the giver of gratification cannot be punished because the Corruption Eradication Law is not designed to punish the giver of gratification even though Samin Tan's position as the giver of gratification is the ultimate beneficiary owner of PT BLEM. The research method used in this research is using normative juridical research methods and using literature study techniques to answer
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17

Lupo, Julien, Audrey Conti, Charlotte Sueur, et al. "Identification of new interacting partners of the shuttling protein ubinuclein (Ubn-1)." Experimental Cell Research 318, no. 5 (2012): 509–20. http://dx.doi.org/10.1016/j.yexcr.2011.12.020.

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18

Helmchen, Christoph, Wolfgang Heide, Michael Strupp, and Dominik Straumann. "Okulomotorikstörungen und Nystagmus." Nervenheilkunde 42, no. 01/02 (2023): 50–58. http://dx.doi.org/10.1055/a-1946-6812.

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ZUSAMMENFASSUNGDer Diagnose von Augenbewegungsstörungen und der Nystagmusformen beruht auf einer systematischen klinischen Untersuchung aller Arten von Augenbewegungen. Diese Untersuchung umfasst: Augenposition, Untersuchung auf einen Spontannystagmus, Motilität, Blickfolge, Blickhaltefunktion, Sakkaden, Vergenzreaktion, optokinetischer Nystagmus, Funktion des vestibulookulären Reflexes (VOR) sowie die Fixationssuppression des VOR. Anatomisch relevante Strukturen sind Mesenzephalon, Pons, Medulla oblongata, Zerebellum und Kortex. Topografisch anatomisch gelten die einfachen klinischen Regeln:
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19

R.W., Oladiran. "Privatization and Financial Performance (Earnings per share) on Selected Money deposit Banks in Nigeria (1980-2015)." American Based Research Journal 8, no. 09 (2019): 01–10. https://doi.org/10.5281/zenodo.3514704.

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<em>The abysmal performance of state owned public enterprises due to the government bureaucracy coupled with corruption has become worrisome to the government and the public. Therefore, economic reforms such as privatization, commercialization and liberalization were carried out to address the aforementioned in federal government establishments. This study investigated the impact of privatization on financial performance of selected DMBs in Nigeria. The study employed ex-post facto research design. T</em><em>hree banks were chosen from the target population of nine privatized deposit money ban
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Pandit, Naba Raj, Dyutiman Choudhary, Shashish Maharjan, Krishna Dhakal, Shree Prasad Vista, and Yam Kanta Gaihre. "Optimum Rate and Deep Placement of Nitrogen Fertilizer Improves Nitrogen Use Efficiency and Tomato Yield in Nepal." Soil Systems 6, no. 3 (2022): 72. http://dx.doi.org/10.3390/soilsystems6030072.

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In Nepal, blanket fertilizer recommendations without considering diverse soil types, nutrient status, climate and crop management practices along with imbalanced fertilization practices by farmers, mainly “urea fertilizer,” have resulted in reduced nitrogen use efficiency (NUE) and productivity in tomato production. Optimizing the rate of nitrogen (N) fertilizer, application time and improved application methods could increase crop yields and NUE and reduce environmental costs. This study was conducted to identify the optimum N rate and application method for increased tomato yield and NUE. Mu
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21

Turriago-Hoyos, Álvaro, William Andrés Martínez Mateus, and Ulf Thoene. "Spatial analysis of multidimensional poverty in Colombia: Applications of the Unsatisfied Basic Needs (UBN) Index." Cogent Economics & Finance 8, no. 1 (2020): 1837441. http://dx.doi.org/10.1080/23322039.2020.1837441.

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Meisel-Roca, Adolfo, and Diana Ricciulli-Marín. "La pobreza en Santa Marta: los estragos del bien." Economía & Región 12, no. 2 (2019): 43–105. http://dx.doi.org/10.32397/er.v12i2.199.

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En 1985, el indicador de pobreza por Necesidades Básicas Insatisfechas (NBI) posicionó a Santa Marta como la ciudad con menor pobreza entre las ocho capitales de la Región Caribe. Dos décadas más tarde, en 2005, Santa Marta empeoró su desempeño relativo, alcanzando un nbi superior al de otras capitales de la región como Barranquilla y Cartagena. Este documento tiene tres objetivos principales: primero, realizar una caracterización espacial de la pobreza en Santa Marta; segundo, investigar las razones del rezago relativo en reducción de pobreza; y tercero, proponer una serie de inversiones para
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23

Naik, M. Vinod Kumar, P. Madhusudhan, Lakshminarayana Vemireddy, et al. "Screening of Rice Germplasm against blast disease for Identification of Resistant Sources." Journal of Phytopharmacology 10, no. 2 (2021): 144–50. http://dx.doi.org/10.31254/phyto.2021.10212.

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Rice Leaf Blast disease is caused by means of Magnaporthe oryzae is one of the major biotic stresses of rice in India. To find the leaf blast resistance sources in rice accessions, an open field investigation was carried in natural and artificial epiphytotic form during rabi seasons in 2018 and 2019. A total of 97 rice genotypes including resistant check (Tetep) and susceptible check (NLR34242 and BPT5204) were grown, in uniform blast nursery (UBN). Rice Leaf blast disease severity assessment was scored according to 0-9 scale. Among rice genotypes,21.6 % were resistant, 29.8 % moderately resis
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Giovannetti, Federico, Marcos Luis Pietto, María Soledad Segretín, and Sebastián Javier Lipina. "Impact of an Individualized Cognitive Training Intervention in Preschoolers from Poor Homes." International Journal of Environmental Research and Public Health 17, no. 8 (2020): 2912. http://dx.doi.org/10.3390/ijerph17082912.

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Over the last few decades, different interventions were shown to be effective in changing cognitive performance in preschoolers from poor homes undertaking tasks with executive demands. However, this evidence also showed that not all children included in the intervention groups equally increased their performance levels, which could be related to individual and contextual variability. The present study aimed to explore the impact of a computerized cognitive training intervention with lab-based tasks in preschoolers from Unsatisfied Basic Needs (UBN) homes under the consideration of their basel
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Ryu, Kwon-Yul, Shamim A. Sinnar, Laura G. Reinholdt, et al. "The Mouse Polyubiquitin Gene Ubb Is Essential for Meiotic Progression." Molecular and Cellular Biology 28, no. 3 (2007): 1136–46. http://dx.doi.org/10.1128/mcb.01566-07.

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ABSTRACT Ubiquitin is encoded in mice by two polyubiquitin genes, Ubb and Ubc, that are considered to be stress inducible and two constitutively expressed monoubiquitin (Uba) genes. Here we report that targeted disruption of Ubb results in male and female infertility due to failure of germ cells to progress through meiosis I and hypogonadism. In the absence of Ubb, spermatocytes and oocytes arrest during meiotic prophase, before metaphase of the first meiotic division. Although cellular ubiquitin levels are believed to be maintained by a combination of functional redundancy among the four ubiq
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Abera, Wuletawu, Luca Brocca, and Riccardo Rigon. "Comparative evaluation of different satellite rainfall estimation products and bias correction in the Upper Blue Nile (UBN) basin." Atmospheric Research 178-179 (September 2016): 471–83. http://dx.doi.org/10.1016/j.atmosres.2016.04.017.

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Mulualem, Getachew Mehabie, and Yuei-An Liou. "Application of Artificial Neural Networks in Forecasting a Standardized Precipitation Evapotranspiration Index for the Upper Blue Nile Basin." Water 12, no. 3 (2020): 643. http://dx.doi.org/10.3390/w12030643.

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The occurrence frequency of drought has intensified with the unprecedented effect of global warming. Knowledge about the spatiotemporal distributions of droughts and their trends is crucial for risk management and developing mitigation strategies. In this study, we developed seven artificial neural network (ANN) predictive models incorporating hydro-meteorological, climate, sea surface temperatures, and topographic attributes to forecast the standardized precipitation evapotranspiration index (SPEI) for seven stations in the Upper Blue Nile basin (UBN) of Ethiopia from 1986 to 2015. The main a
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P, Umamahesh, P. Gonya Nayak, B. Laxmi Prasanna, and T. Yella Goud. "Phenotypic Screening of Advanced Breeding Lines for Blast Resistance in Rice (Oryza sativa L.)." Journal of Experimental Agriculture International 46, no. 8 (2024): 415–20. http://dx.doi.org/10.9734/jeai/2024/v46i82718.

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Rice is predominantly grown in Asia, which accounts for about 90% of global production. Rice crop is affected by both biotic and abiotic stresses, biotic stresses such as blast, bacterial blight which significantly reduces the yields. Present study was conducted to introgress the blast gene Pi54 into the genetic background of the rice variety Telangana Sona (RNR 15048) through marker assisted pedigree breeding. A cross was made between Telangana Sona (RNR 15048) and near isogenic line of Cottondora Sannalu (MTU1010NIL). A set of 40 advanced breeding lines (F5) were screened phenotypically for
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Lomaglio, Delia B., and Rosario E. Pacheco Agüero. "Trend in the Prevalence of Overweight, Obesity, and Body Fat Distribution in Children and Adolescents in Northwestern Argentina Between 1982 and 2019." Obesities 5, no. 1 (2025): 11. https://doi.org/10.3390/obesities5010011.

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The aim of this work was to analyze the trend of overweight, obesity, and body fat distribution of children and adolescents in Catamarca, northwest Argentina, in the last four decades. A data series obtained between 1982 and 2019 in the province of Catamarca was analyzed. The sample of 5596 individuals (46.41% female), between 5 and 14 years old, was grouped into four decades: 1980, 1990, 2000, and 2010. The categories of overweight and obesity, based on body mass index (BMI), were defined from the international reference IOTF. The fat distribution was defined according to the subscapular tric
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Hermanasari, Rini, NFN Supartopo, and B. Kustianto. "Penampilan Fenotipik Karakter Hasil Galur Harapan Padi Rawa di Lahan Pasang Surut Karang Agung, Sumatera Selatan." Buletin Plasma Nutfah 17, no. 1 (2016): 19. http://dx.doi.org/10.21082/blpn.v17n1.2011.p19-24.

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&lt;p&gt;Phenotypic Performance of Yield and Yield Component of Rice Promising Lines at Tidal Swamp Area in Karang Agung, South Sumatra. An experiment was conducted in Karang Agung, in April until September 2007. The experiment aimed at evaluating phenotypic performance of yield and yield components of promising lines in tidal swamp rice field. The experiment was arranged in a Randomized Complete Block Design with 16 treatments and four replications. The promising lines tested were B9858-KA-55, B9833C-KA-14, B9852E-KA-66, B5524G-SM-61-2-1, B7003D-MR-24-3-1, KAL9414F-MR-2-KN-0, KAL9418F-MR-2-KN
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Monfort, Asun, Giulio Di Minin, Sarah Sting, Charles Etienne Dumeau, Peter Scambler, and Anton Wutz. "Ubinuclein 2 is essential for mouse development and functions in X chromosome inactivation." PLOS Genetics 21, no. 6 (2025): e1011711. https://doi.org/10.1371/journal.pgen.1011711.

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The HIRA complex mediates deposition of histone H3.3 independent of replication. Its functions in gene regulation in mice remain to be fully understood. Here we analyze mutations of the HIRA complex genes Ubn1 and Ubn2. We observe that Ubn1 mutant mice of both sexes are viable and fertile. In contrast, mutation of Ubn2 causes embryonic lethality with variable penetrance and skewed sex ratio in favor of males. Combined Ubn1 and Ubn2 mutations cause embryonic lethality with complete penetrance, variable developmental arrest before turning, and reduced recovery of female embryos. Consistent with
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Jantrapirom, Salinee, Luca Lo Piccolo, and Masamitsu Yamaguchi. "Non-Proteasomal UbL-UbA Family of Proteins in Neurodegeneration." International Journal of Molecular Sciences 20, no. 8 (2019): 1893. http://dx.doi.org/10.3390/ijms20081893.

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Ubiquitin-like/ubiquitin-associated proteins (UbL-UbA) are a well-studied family of non-proteasomal ubiquitin receptors that are evolutionarily conserved across species. Members of this non-homogenous family facilitate and support proteasomal activity by promoting different effects on proteostasis but exhibit diverse extra-proteasomal activities. Dysfunctional UbL-UbA proteins render cells, particularly neurons, more susceptible to stressors or aging and may cause earlier neurodegeneration. In this review, we summarized the properties and functions of UbL-UbA family members identified to date,
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Piątkowska, Daria, Anna Klimaszewska-Wiśniewska, Alicja Kosińska, Radosław Wujec, Dariusz Grzanka та Justyna Durślewicz. "Ubiquitin B, Ubiquitin C, and β-Catenin as Promising Diagnostic and Prognostic Tools in Prostate Cancer". Cancers 16, № 5 (2024): 902. http://dx.doi.org/10.3390/cancers16050902.

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Prostate cancer (PC) is a major global public health concern, imposing a significant burden on men and ranking as the second most prevalent malignancy. This study delves into the intricate world of ubiquitination processes and expression regulation, with a specific focus on understanding the roles of ubiquitin B (UBB), ubiquitin C (UBC), and β-Catenin in PC development. We thoroughly analyze the expression profiles of UBB, UBC, and β-Catenin, investigating their interactions and associations with clinical and histopathological data. These findings offer valuable insights into their potential a
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Hara, Taichi, Takumi Kamura, Shuhei Kotoshiba, et al. "Role of the UBL-UBA Protein KPC2 in Degradation of p27 at G1 Phase of the Cell Cycle." Molecular and Cellular Biology 25, no. 21 (2005): 9292–303. http://dx.doi.org/10.1128/mcb.25.21.9292-9303.2005.

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ABSTRACT KPC2 (Kip1 ubiquitylation-promoting complex 2) together with KPC1 forms the ubiquitin ligase KPC, which regulates degradation of the cyclin-dependent kinase inhibitor p27 at the G1 phase of the cell cycle. KPC2 contains a ubiquitin-like (UBL) domain, two ubiquitin-associated (UBA) domains, and a heat shock chaperonin-binding (STI1) domain. We now show that KPC2 interacts with KPC1 through its UBL domain, with the 26S proteasome through its UBL and NH2-terminal UBA domains, and with polyubiquitylated proteins through its UBA domains. The association of KPC2 with KPC1 was found to stabi
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Karyawati, Anna Satyana, Gita Novita Sari, and Budi Waluyo. "Variabilitas genetik, heritabilitas dan kemajuan genetik beberapa karakter kuantitatif galur F3 kedelai hasil persilangan." Jurnal Agro 6, no. 2 (2019): 134–43. http://dx.doi.org/10.15575/5174.

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Parameter genetik seperti keragaman genetik, heritabilitas dan kemajuan genetik diperlukan untuk merakit kultivar unggul. Untuk itu dialukan evaluasi keragaman genetik, heritabilitas dan kemajuan genetik populasi galur F3 kedelai dari 16 kombinasi persilangan dengan 6 tetua pada beberapa karakter kuantitatif diantaranya yaitu tinggi tanaman, jumlah cabang, jumlah polong isi, jumlah buku subur dan berat biji per tanaman. Penelitian untuk menyiapkan materi genetik dilakukan di Kebun Percobaan Fakultas Pertanian Universitas Brawijaya, Jatikerto, Malang pada tahun 2013-2016. Percobaan menggunakan
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Journal, Baghdad Science. "Role of TGF-?1 in Urinary Bladder Carcinoma." Baghdad Science Journal 11, no. 4 (2014): 1481–85. http://dx.doi.org/10.21123/bsj.11.4.1481-1485.

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The present study aimed to evaluate sera TGF- ?1 concentration in patients with urinary bladder carcinoma (UBC). All malignant of them was transitional cell carcinoma (TCC) type , patients with urinary bladder disorders (UBD ) and healthy control , and to study the correlation between sera TGF-?1 levels and tumor stages and grades in UBC patients . A direct ELISA test was used to quantify the seraTGF-?1 concentrations in sera of 58 patients with urinary bladder carcinoma UBC of different grades (G) and stages (T) all malignant of them was transitional cell carcinoma (TCC) type , 15 from patien
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Mousa, Hind M., Amna N. Jassem, and Munther J. Hussain. "Role of TGF-?1 in Urinary Bladder Carcinoma." Baghdad Science Journal 11, no. 4 (2014): 1481–85. http://dx.doi.org/10.21123/bsj.2014.11.4.1481-1485.

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The present study aimed to evaluate sera TGF- ?1 concentration in patients with urinary bladder carcinoma (UBC). All malignant of them was transitional cell carcinoma (TCC) type , patients with urinary bladder disorders (UBD ) and healthy control , and to study the correlation between sera TGF-?1 levels and tumor stages and grades in UBC patients . A direct ELISA test was used to quantify the seraTGF-?1 concentrations in sera of 58 patients with urinary bladder carcinoma UBC of different grades (G) and stages (T) all malignant of them was transitional cell carcinoma (TCC) type , 15 from patien
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Zhang, Heng, Xu Yang, Zhu Ying, Jing Liu, and Qun Liu. "Toxoplasma gondii UBL-UBA Shuttle Protein DSK2s Are Important for Parasite Intracellular Replication." International Journal of Molecular Sciences 22, no. 15 (2021): 7943. http://dx.doi.org/10.3390/ijms22157943.

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Toxoplasma gondii (T. gondii) is an important human and veterinary pathogen causing life-threatening disease in immunocompromised patients. The UBL-UBA shuttle protein family are important components of the ubiquitin–proteasome system. Here, we identified a novel UBL-UBA shuttle protein DSK2b that is charactered by an N-terminal ubiquitin-like domain (UBL) and a C-terminal ubiquitin-associated domain (UBA). DSK2b was localized in the cytoplasm and nucleus. The deletion of dsk2b did not affect the degradation of ubiquitinated proteins, parasite growth in vitro or virulence in mice. The double-g
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Azorsa, David O., David W. Lee, Marvin O'Ketch, et al. "Abstract 4096: Development of novel anticancer RNA therapeutics with dual-targeting siRNA that silences ubiquitin family members." Cancer Research 82, no. 12_Supplement (2022): 4096. http://dx.doi.org/10.1158/1538-7445.am2022-4096.

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Abstract Ubiquitination is a metabolic process in eukaryotic cells that modifies proteins with ubiquitin leading to protein degradation via the ubiquitin-proteosome pathway. Cellular levels of ubiquitin are driven by the expression of RPS27A, UBA52, UBB and UBC. In cancer, the dysregulation of ubiquitination can affect various aspects of tumor progression including cell cycle regulation and gene expression. Ubiquitin B (UBB) gene has been shown to be over-expressed in some tumor types, including NSCLC and cervical cancer, and under-expressed in other tumors, in particularly a subset of ovarian
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Martinez, Jorge Ivan, Marcelo Isidro Figueroa, José Miguel Martínez-Carrión, Emma Laura Alfaro-Gomez, and José Edgardo Dipierri. "Birth Size and Maternal, Social, and Environmental Factors in the Province of Jujuy, Argentina." International Journal of Environmental Research and Public Health 19, no. 2 (2022): 621. http://dx.doi.org/10.3390/ijerph19020621.

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Introduction: birth size is affected by diverse maternal, environmental, social, and economic factors. Aim: analyze the relationships between birth size—shown by the indicators small for gestational age (SGA) and large for gestational age (LGA)—and maternal, social, and environmental factors in the Argentine province of Jujuy, located in the Andean foothills. Methods: data was obtained from 49,185 mother-newborn pairs recorded in the Jujuy Perinatal Information System (SIP) between 2009 and 2014, including the following: newborn and maternal weight, length/height, and body mass index (BMI); ge
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Ibrahim Mohammed, Jemal, and Bogale Gebramariam. "Performance Assessment of Cascaded Reservoirs Operation Under the Impact of Climate Change the Case of Lower and upper Dabus Reservoirs, UBN Basin, Ethiopia." International Journal of Energy and Environmental Science 6, no. 2 (2021): 29. http://dx.doi.org/10.11648/j.ijees.20210602.12.

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Journal, Baghdad Science. "Heat Shock Protein70 as Biomarker in Bladder Cancer." Baghdad Science Journal 11, no. 3 (2014): 1130–35. http://dx.doi.org/10.21123/bsj.11.3.1130-1135.

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The present study aimed to shed light on the urine HSP70 concentration of patients with urinary bladder carcinoma UBC and control subjects as new urinary biomarker. The second aim was to associate this protein concentration with UBC stage and grade in patients with UBC. A direct ELISA was used to quantify urine HSP concentrations in 58 patients with urinary bladder carcinoma UBC with different grades (G) and stages (T) all malignant of them was transitional cell carcinoma (TCC) type , 15 from patients with urinary Bladder disorders other than cancer UBD and 15 healthy subjects(control) . Urine
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Hirayama, Shoshiro, Munechika Sugihara, Daisuke Morito, et al. "Nuclear export of ubiquitinated proteins via the UBIN-POST system." Proceedings of the National Academy of Sciences 115, no. 18 (2018): E4199—E4208. http://dx.doi.org/10.1073/pnas.1711017115.

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Although mechanisms for protein homeostasis in the cytosol have been studied extensively, those in the nucleus remain largely unknown. Here, we identified that a protein complex mediates export of polyubiquitinated proteins from the nucleus to the cytosol. UBIN, a ubiquitin-associated (UBA) domain-containing protein, shuttled between the nucleus and the cytosol in a CRM1-dependent manner, despite the lack of intrinsic nuclear export signal (NES). Instead, the UBIN binding protein polyubiquitinated substrate transporter (POST) harboring an NES shuttled UBIN through nuclear pores. UBIN bound to
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Arrasco, Juan, José Medina, Luis Ordoñez, Elena Vargas Linares, and Willy Ramos. "Características de la mortalidad por COVID-19 durante y después de la pandemia en el Perú." Anales de la Facultad de Medicina 85, no. 3 (2024): 259–67. http://dx.doi.org/10.15381/anales.v85i3.28037.

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Introduction. The COVID-19 emergency caused a pandemic with a great impact on mortality in Peru. Objective. To analyze the magnitude of mortality due to COVID-19 and identify some sociodemographic characteristics. Methods. A descriptive ecological study was carried out, analyzing data on deaths due to COVID-19 during the period 2020-2023, as well as publicly accessible socioeconomic and demographic indicators. The variables included in the study were: year of death, number of deaths, sex, age group, province of origin, natural region, macroregion, human development index (HDI), unmet basic nee
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Lohr, Lawrence L. "Relativistically parameterized extended H�ckel calculations. 13. Energy bands for uranium compounds UB2, UB4, UC, UBC, and UPt3." International Journal of Quantum Chemistry 40, S25 (1991): 121–30. http://dx.doi.org/10.1002/qua.560400815.

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Kim, Ikjin, Kaixia Mi, and Hai Rao. "Multiple Interactions of Rad23 Suggest a Mechanism for Ubiquitylated Substrate Delivery Important in Proteolysis." Molecular Biology of the Cell 15, no. 7 (2004): 3357–65. http://dx.doi.org/10.1091/mbc.e03-11-0835.

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The mechanism underlying the delivery of ubiquitylated substrates to the proteasome is poorly understood. Rad23 is a putative adaptor molecule for this process because it interacts with ubiquitin chains through its ubiquitin-associated motifs (UBA) and with the proteasome through a ubiquitin-like element (UBL). Here, we demonstrate that the UBL motif of Rad23 also binds Ufd2, an E4 enzyme essential for ubiquitin chain assembly onto its substrates. Mutations in the UBL of Rad23 alter its interactions with Ufd2 and the proteasome, and impair its function in the UFD proteolytic pathway. Furthermo
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Li, Lan, Bin Li, Chong Xie, et al. "Arabidopsis RAD23B regulates pollen development by mediating degradation of KRP1." Journal of Experimental Botany 71, no. 14 (2020): 4010–19. http://dx.doi.org/10.1093/jxb/eraa167.

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Abstract The ubiquitin (Ub)/26S proteasome system (UPS) plays a key role in plant growth, development, and survival by directing the turnover of numerous regulatory proteins. In the UPS, the ubiquitin-like (UBL) and ubiquitin-associated (UBA) domains function as hubs for ubiquitin-mediated protein degradation. Radiation sensitive 23 (RAD23), which has been identified as a UBL/UBA protein, contributes to the progression of the cell cycle, stress responses, ER proteolysis, and DNA repair. Here, we report that pollen development is arrested at the microspore stage in a rad23b null mutant. We demo
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Kleijnen, Maurits F., Rodolfo M. Alarcón, and Peter M. Howley. "The Ubiquitin-associated Domain of hPLIC-2 Interacts with the Proteasome." Molecular Biology of the Cell 14, no. 9 (2003): 3868–75. http://dx.doi.org/10.1091/mbc.e02-11-0766.

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The ubiquitin-like hPLIC proteins can associate with proteasomes, and hPLIC overexpression can specifically interfere with ubiquitin-mediated proteolysis ( Kleijnen et al., 2000 ). Because the hPLIC proteins can also interact with certain E3 ubiquitin protein ligases, they may provide a link between the ubiquitination and proteasomal degradation machineries. The amino-terminal ubiquitin-like (ubl) domain is a proteasome-binding domain. Herein, we report that there is a second proteasome-binding domain in hPLIC-2: the carboxyl-terminal ubiquitin-associated (uba) domain. Coimmunoprecipitation ex
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Peñaherrera Cabezas, Jorge. "Metodología para el cálculo de la distribución de los recursos fiscales para los Gobiernos Autónomos Descentralizados en Ecuador: análisis de su aplicación / A Methodology for calculating the distribution of fiscal resources for the local councils in Ecuador: an analysis of its application." Ciencia Unemi 8, no. 16 (2015): 21. http://dx.doi.org/10.29076/issn.2528-7737vol8iss16.2015pp21-31p.

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Establecen la transferencia de competencias con recursos a los Gobiernos Autónomos Descentralizados (GAD), los mismos que buscan el equilibrio y solidaridad entre las poblaciones. Siete criterios se evalúan para determinar los montos a transferirse a cada GAD, de acuerdo a una metodología elaborada ex profeso. La revisión de la metodología indica que los criterios utilizados no son mutuamente excluyentes, y que existen inconsistencias en su aplicación. Esto incluye que diferentes criterios puntúen positivamente valores contrarios de las Necesidades Básicas Insatisfechas (NBI), y que las transf
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Ramalingam, Jegadeesan, Savitha Palanisamy, Ganesh Alagarasan, Vellaichamy Gandhimeyyan Renganathan, Ayyasamy Ramanathan, and Ramasamy Saraswathi. "Improvement of Stable Restorer Lines for Blast Resistance through Functional Marker in Rice (Oryza sativa L.)." Genes 11, no. 11 (2020): 1266. http://dx.doi.org/10.3390/genes11111266.

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Two popular stable restorer lines, CB 87 R and CB 174 R, were improved for blast resistance through marker-assisted back-cross breeding (MABB). The hybrid rice development program in South India extensively depends on these two restorer lines. However, these restorer lines are highly susceptible to blast disease. To improve the restorer lines for resistance against blasts, we introgressed the broad-spectrum dominant gene Pi54 into these elite restorer lines through two independent crosses. Foreground selection for Pi54 was done by using gene-specific functional marker, Pi54 MAS, at each back-c
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