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Rozprawy doktorskie na temat „Ulcer wounds”

Autor: Grafiati

Data publikacji: 2 czerwca 2025

Data aktualizacji: 31 lipca 2025

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1

Lazurko, Caitlin. "Nanomaterial and Biomaterial Approaches for Treating Chronic Wounds." Thesis, Université d'Ottawa / University of Ottawa, 2019. http://hdl.handle.net/10393/39338.

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Diabetic foot ulcers (DFUs) are a common and severe adverse event associated with diabetes, as 25% of diabetic patients will experience DFUs. The lack of effective DFU therapies results in 20% of diabetic patients requiring amputation. We first developed an algorithm to account for polydispersity when calculating nanoparticle concentration, which will reduce variability between batches and treatments. We also developed a novel 2-layer biomaterial, which combines anti-microbial properties of CLKRS peptide coated silver nanoparticles (CLKRS- AgNPs) with a pro-regenerative collagen matrix embedde

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Wall, Steven J. "Differential expression of matrix metalloproteinases in impaired wound healing of the diabetes mouse." Thesis, University of East Anglia, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.365007.

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Broszczak, Daniel Aaron. "Molecular profiling of exudate from chronic ulcerated wounds." Thesis, Queensland University of Technology, 2015. https://eprints.qut.edu.au/79907/1/Daniel_Broszczak_Thesis.pdf.

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Non-healing wounds represent a significant burden to healthcare systems and societies worldwide. Current best practice treatments of chronic wounds can require patients to undergo extensive periods of therapy without any positive outcome. This consumes substantial healthcare resources and severely impacts patient quality of life. At present, there are no measures to predict a patient's response to best practice care. The hypothesis of this thesis was that biochemical markers could be found within the wound fluid of chronic ulcers and these markers could predict the healing outcome of an ulcer

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Childress, Beverly Bibera. "Nitric oxide metabolites in wound fluids from pressure ulcers on v.a.c.(tm) therapy." [Gainesville, Fla.] : University of Florida, 2004. http://purl.fcla.edu/fcla/etd/UFE0005140.

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Thesis (Ph.D.)--University of Florida, 2004.<br>Typescript. Title from title page of source document. Document formatted into pages; contains 84 pages. Includes Vita. Includes bibliographical references.

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Silveira, Isabelle Andrade. "Leg Ulcer Measurement Tool : tradução e adaptação transcultural para a língua portuguesa." Universidade Federal Fluminense, 2016. https://app.uff.br/riuff/handle/1/3012.

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Submitted by Fabiana Gonçalves Pinto (benf@ndc.uff.br) on 2017-03-07T18:26:02Z No. of bitstreams: 1 Isabelle Andrade Silveira.pdf: 1744842 bytes, checksum: 517b4f56d05e86c90f2f3978129e864a (MD5)<br>Made available in DSpace on 2017-03-07T18:26:02Z (GMT). No. of bitstreams: 1 Isabelle Andrade Silveira.pdf: 1744842 bytes, checksum: 517b4f56d05e86c90f2f3978129e864a (MD5) Previous issue date: 2016<br>Mestrado Acadêmico em Ciências do Cuidado em Saúde<br>Introdução: O Leg Ulcer Measurement Tool é um instrumento desenvolvido no Canadá especificamente para avaliar úlceras de perna. Composto por

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Broadbent, James Aubrey. "Proteomic systems analysis of the proximal fluid from chronic wounds implicates a novel mechanism of disease perpetuation and tissue destruction." Thesis, Queensland University of Technology, 2011.

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Chronic wounds pose a substantial burden to healthcare systems, affected individuals and their personal support networks. In general, this condition presents as the inability of skin to heal, leaving patients with open wounds for extended periods of time. Such patients experience constant pain, reduced mobility, depression, social isolation and reduced quality-of-life. In addition, direct fiscal costs to the Australian healthcare system are estimated to be in excess of $2.6 billion annually and substantially higher in the United States and United Kingdom. While this condition has been the subj

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Franck, Ednalda Maria. "Alterações de pele em pacientes em cuidados paliativos na terminalidade da doença e final da vida: coorte prospectiva." Universidade de São Paulo, 2016. http://www.teses.usp.br/teses/disponiveis/7/7139/tde-17052017-112324/.

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Introdução: Os pacientes com doenças avançadas, ameaçadoras da vida, de qualquer etiologia, podem apresentar intercorrências ao longo do curso da doença e nem sempre é fácil para o profissional diferenciar rapidamente se ele está em terminalidade da doença ou fase final de vida, pois a piora do quadro clínico pode ser devida a algo reversível. Tendo em vista que a pele é considerada o maior órgão do corpo humano, assim como ocorre com os demais órgãos, pode sofrer disfunção quando a pessoa está em fase final de vida. Nesse contexto, a disfunção da pele está relacionada à diminuição da perfusão

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Coull, Alison Frances. "Leg ulceration in young people who inject drugs : causative factors, and how harm may be reduced : a mixed methods approach." Thesis, University of Stirling, 2016. http://hdl.handle.net/1893/24081.

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The thesis explores chronic leg ulceration experienced by young people who inject drugs (PWID). The applied health research study, in two phases, used a sequential explanatory mixed methods design. Phase 1 involved a survey of 200 people who injected drugs to investigate the prevalence of skin problems and leg ulceration, together with the identification of risk factors for ulceration. Phase 2 involved a series of fifteen qualitative semi-structured interviews that explored the results relating to risk factors with a sample of PWID who had experienced leg ulceration, and investigated participa

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Shin, Vivian Yvonne, and 冼念慈. "A mechanistic study on the adverse effects of cigarette smoke extractson the delay of gastric ulcer healing." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2001. http://hub.hku.hk/bib/B3122510X.

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Loots, Miriam Alfonsa Maria. "Wound healing in diabetic ulcers." [S.l. : Amsterdam : s.n.] ; Universiteit van Amsterdam [Host], 2002. http://dare.uva.nl/document/66897.

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Pereira, Talita de Azevedo Coelho Furquim. "Feridas complexas classificação de tecidos, segmentação e mensuração com o classificador Optimun-Path Forest /." Universidade Estadual Paulista (UNESP), 2018. http://hdl.handle.net/11449/153761.

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Submitted by Talita De Azevedo Coelho Furquim Pereira (talitapereira@bauru.sp.gov.br) on 2018-04-24T00:47:22Z No. of bitstreams: 1 Dissertação - final repositório.pdf: 1807192 bytes, checksum: 3197e207676b603a47d2146acf83b045 (MD5)<br>Approved for entry into archive by ROSANGELA APARECIDA LOBO null (rosangelalobo@btu.unesp.br) on 2018-04-26T16:58:24Z (GMT) No. of bitstreams: 1 pereira_tacf_me_bot.pdf: 1807192 bytes, checksum: 3197e207676b603a47d2146acf83b045 (MD5)<br>Made available in DSpace on 2018-04-26T16:58:24Z (GMT). No. of bitstreams: 1 pereira_tacf_me_bot.pdf: 1807192 bytes, checks

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Scattolini, Valentina. "In vitro and in vivo study of NETosis in diabetic wound healing." Doctoral thesis, Università degli studi di Padova, 2017. http://hdl.handle.net/11577/3422754.

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People with diabetes have an increased risk of developing several serious health problems. One of the most frequent complication is an impaired wound healing. Neutrophils are recruited early to the wound bed and, upon activation, they undergo histone citrullination by protein arginine deiminase (PAD)4, exocytosis of chromatin and enzymes as neutrophil extracellular traps (NETs), and death. This process is called NETosis. In diabetes, neutrophils are primed to release NETs and die by NETosis. Although this process is a defense against infection, excessive NETosis can damage tissue. The aim of

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Bagley, Angus H. "Proteomic and bioinformatic investigation of chronic wounds using non-invasive sampling to assess wound status and pathology." Thesis, Queensland University of Technology, 2022. https://eprints.qut.edu.au/235131/1/Angus_Bagley_Thesis.pdf.

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This project explored the biochemistry of non-healing wounds, with aims of expanding the current knowledge on their associated protein profiles. Changes in the abundance levels of proteins within wound fluids were examined in relation to best-practice treatments, including compression therapy, and wound condition, including infection status and disease burden. A complex statistical methodology was developed to analyse wound proteomic mass spectrometry data. This approach identified a suite of significant and clinically relevant protein targets. These findings may benefit wounds research and cl

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14

O'Meara, Susan Mary. "Studies in chronic wound healing : synthesising data and measuring ulcer dimensions." Thesis, University of York, 2007. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.444709.

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Jones, Timothy David. "Improving the precision of leg ulcer area measurement with active contour models." Thesis, University of South Wales, 1999. https://pure.southwales.ac.uk/en/studentthesis/improving-the-precision-of-leg-ulcer-area-measurement-with-active-contour-models(b365998c-1ae3-44b1-8232-c5f4a8121f97).html.

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A leg ulcer is a chronic wound of the skin that, at best, takes many months to fully heal and causes great distress to the patient. Treating leg ulcers places a large financial burden upon the National Health Service in the United Kingdom, estimated to be in excess of £300M annually. Measurement of the size of leg ulcers is a guide to assessing the progress of wound healing, and the use of non-invasive measurement techniques avoids damaging or infecting the wound. The area of a leg ulcer is currently measured by presenting a human observer with a captured video image of a wound, who then uses

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16

McGinnis, Elizabeth. "Heel pressure ulcers : a study of wound healing." Thesis, University of Leeds, 2011. http://etheses.whiterose.ac.uk/2802/.

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Background Heels are a common location for pressure ulcers (PUs); they may be physiologically different to other PU sites and their healing is poorly understood. Aim To summarise the effects of support surfaces and identify prognostic factors in healing heel PUs. Objectives 1. Review the effects of support surfaces for heel PU healing 2. Identify factors which independently impact on heel PU healing 3. Describe the characteristics of patients, current management practices and progress of heel PUs Methods Systematic review of the evidence of effectiveness for pressure relieving devices in the t

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Sandhu, Sumeet. "Understanding the diabetic foot ulcer microbiome and its impact on wound severity." Thesis, Queensland University of Technology, 2021. https://eprints.qut.edu.au/208392/1/Sumeet_Sandhu_Thesis.pdf.

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This research investigated the three major dimensions of the Diabetic Foot Ulcer (DFU) bioburden: microbial diversity, microbial load, and pathogenic determinants. Next generation sequencing was used to determine the impact of bacterial diversity on healing and non-healing DFUs. Healing DFUs have a significantly greater bacterial diversity compared to non-healing DFUs. For healing DFUs, bacterial species were identified that could be further investigated for their probiotic potential to promote wound healing. This research generated a significant body of knowledge to the three dimensions of DF

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18

Ebbeskog, Britt. "Elderly patients with slow-healing leg ulcers : an embodied suffering /." Stockholm, 2003. http://diss.kib.ki.se/2003/91-7349-492-5/.

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Bui, Ut Thi. "Risk factors associated with infection in patients with chronic leg ulcers." Thesis, Queensland University of Technology, 2019. https://eprints.qut.edu.au/134477/14/Ut_Thi_Bui_Thesis.pdf.

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This thesis provides the most comprehensive information available to date, about the presentation of infection, and factors associated with an increased likelihood of developing infection in chronic leg ulcers. These factors include comorbid conditions, medications, psychosocial factors, and local lower-limb factors. A conceptual framework, named Factors for Infection in Chronic Leg Ulcers or FICLUs, was also constructed, which can be used to guide future research in wounds. The thesis recommends a holistic approach when assessing patients with chronic leg ulcers and early interventions to pre

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Cannizzo, Carla Maria. "MicroRNAs: Markers and Mediators of Wound Healing in Diabetes." Thesis, The University of Sydney, 2021. https://hdl.handle.net/2123/25885.

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Chronic non-healing foot ulcers are a major complication of diabetes, occurring in 25% of patients within their lifetime. A common feature that underpins poor wound healing in diabetes is inadequate vascularisation due to diabetes-impaired angiogenesis. Currently there are no adequate biomarkers and effective therapies that improve diabetes-impaired healing. The ability to better identify and treat these wounds would reduce the risk of developing co-morbidities such as lower limb amputations. microRNAs (miRNAs) have been indicated to be reliable biomarkers and have been shown to be dysregulat

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MARTINS, Marlene Andrade. "Avaliação de feridas crônicas em pacientes atendidos em Unidades Básicas de Saúde de Goiânia." Universidade Federal de Goiás, 2008. http://repositorio.bc.ufg.br/tede/handle/tde/698.

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Made available in DSpace on 2014-07-29T15:04:30Z (GMT). No. of bitstreams: 1 dissertacao marleneandrade.pdf: 776220 bytes, checksum: 89f7e969fbef687591092b3ded9dd40a (MD5) Previous issue date: 2008-04-30<br>Assessing patients with chronic wounds poses a challenge to professionals and doubts still persist concerning characterization of the wound infection status. We believe that the Basic Health Units are in places of reference for the public to submit chronic wounds and should have full attendance and resolution were objectives of this study: characterizing patients with chronic wounds atten

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Lima, Ricardo de Oliveira. "CicatrizaÃÃo da Ãlcera por PressÃo Experimental com FumaÃa de Moxa Palito de Artemisia vulgaris em Comundongos." Universidade Federal do CearÃ, 2013. http://www.teses.ufc.br/tde_busca/arquivo.php?codArquivo=11395.

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CoordenaÃÃo de AperfeiÃoamento de Pessoal de NÃvel Superior<br>Ãlcera por pressÃo (UP) Ã uma lesÃo comum entre idosos e indivÃduos com mobilidade fÃsica prejudicada. Ela afeta a qualidade de vida dos indivÃduos e gera custos considerÃveis, uma vez que estÃ se tornando um problema mundial crescente, devido ao envelhecimento da populaÃÃo. Ciclos de isquemia e reperfusÃo tÃm sido identificados como fatores causais primÃrios, mas existem outros fatores que influenciam a intensidade dos danos. Atualmente, nÃo existe um mÃtodo eficaz e de baixo custo para tratar esta condiÃÃo. O uso clÃnico da fumaÃ

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Shin, Vivian Yvonne. "A mechanistic study on the adverse effects of cigarette smoke extracts on the delay of gastric ulcer healing /." Hong Kong : University of Hong Kong, 2001. http://sunzi.lib.hku.hk:8888/cgi-bin/hkuto%5Ftoc%5Fpdf?B23424813.

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Hjelm, Michaela, and Maria Karlsson. "Sårläkningstid hos äldre patienter med diabetes och fotsår : fokus på omläggningsmaterial." Thesis, Högskolan Väst, Avdelningen för omvårdnad - avancerad nivå, 2016. http://urn.kb.se/resolve?urn=urn:nbn:se:hv:diva-9418.

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Diabetes is a growing public health problem that can lead to serious complications for the pa-tient such as foot ulcers and amputations. For affected patients the foot ulcers causes suffer-ing, pain and impaired health. The foot ulcers also contribute to major costs to the society and affects healthcare resources hard. A large part of the district nurse's work consists of wound care. Therefore it is important that the district nurse possess adequate knowledge of wound dressings to promote wound healing and thereby shorten the wound healing time. The aim of the study was to examine the wound he

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Henshaw, Frances Rachel. "The effect of topical therapies on ulcer healing and the wound micro-environment in diabetes mellitus." Thesis, The University of Sydney, 2014. http://hdl.handle.net/2123/12509.

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Wounds in people with diabetes typically show abnormal healing. The diabetic wound is generally characterised by its chronicity, persistent inflammation, copious exudate, hypergranulation, increased bacterial load and reduced ability to heal. This delayed healing is thought to be attributable to a variety of factors including micro- and macrovascular disease, neuropathy, bacterial infection, local pressure due to foot deformity and the adverse local metabolic environment caused by diabetes. The series of studies presented in this thesis demonstrate for the first time that the topical growth fa

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Tuttle, Marie S. "Microbial Bioburden in Venous Leg Ulcers." Case Western Reserve University School of Graduate Studies / OhioLINK, 2014. http://rave.ohiolink.edu/etdc/view?acc_num=case1409912389.

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McGuiness, William Garold George, and w. mcguiness@latrobe edu au. "Using colour exhibited by venous leg ulcers to develop a range of hues that represent the clinical manifestations of erythema and wet necrotic tissue." Flinders University. Medicine, 2009. http://catalogue.flinders.edu.au./local/adt/public/adt-SFU20090928.110041.

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This project sought to develop a system that facilitated the visual inspection of venous leg ulcers by establishing a selection of reliable parameters. The project had three principal aims: to develop a reliable method for capturing the colours exhibited by a venous leg ulcer; to establish a colour range that experienced clinicians believed represented wet necrotic tissue and erythema; and to develop software that highlighted the two manifestations in digital photographs. The project method was divided into three phases. The first phase examined images taken from twenty-two patients over for

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Clements, B. Alyson. "Low intensity laser therapy (LILT) and combined phototherapy/LILT : effects upon blood flow and wound healing in humans." Thesis, University of Ulster, 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.241724.

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Peters, J. Melanie. "The impact of tele-advice on the community nurses' management of leg ulcers." Thesis, University of South Wales, 2003. https://pure.southwales.ac.uk/en/studentthesis/the-impact-of-teleadvice-on-the-community-nurses-management-of-leg-ulcers(d993ad94-af85-43e0-bdc1-af2c097d65a7).html.

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This study attempted to investigate the impact of new technology, specifically tele-advice on community nurses' care of leg ulcers. Firstly, a stratified randomised controlled study was designed to measure the impact of using this technology on their levels of wound knowledge and confidence. An individual self-test questionnaire and an attitudinal scale measured nurses' knowledge and confidence respectively both pre and post-intervention. Secondly, a new visual wound assessment tool was designed to represent the state of the wound by a single numerical value; the State of the Wound Index (SWI)

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Sweeney, Robin E., Elizabeth Budiman, and Jeong-Yeol Yoon. "Instant scanner device for identifying wound infection utilizing Mie scatter spectra." SPIE-INT SOC OPTICAL ENGINEERING, 2017. http://hdl.handle.net/10150/626485.

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Tissue biopsy and swab culture are the gold standards for diagnosing tissue infection; these tests require significant time, diagnostic costs, and resources. Towards earlier and specific diagnosis of infection, a non-destructive, rapid, and mobile detection device is described to distinguish bacterial species via light scatter spectra from the surface of an infected tissue, reagent-free. Porcine skin and human cadaveric skin models of wound infection were used with a 650 nm LED and an angular photodiode array to detect bacterial infections on the tissue surface, which can easily be translated

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McArdle, Grainne. "The effects of wound fluid pH on bacterial persistence in diabetic foot ulcers." Thesis, Ulster University, 2015. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.730912.

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Nelson, Claire Patricia. "Nutrition and chronic lower leg wounds: Assessing patient status, and exploring health professionals' self-perceived competence." Thesis, Queensland University of Technology, 2021. https://eprints.qut.edu.au/225901/1/Claire_Nelson_Thesis.pdf.

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This research determined the nutrition status of people with chronic lower-leg wounds and explored nutrition care from the perspective of health professionals working with chronic wound populations. The study found that despite high BMI of the group, nearly 20 percent of participants were malnourished and, that in chronic wound care settings malnutrition screening and management may be insufficient. The research was conducted within a nutrition-focused socio-ecological framework. Nutrition status was determined by considering dietary intake, health, demographic profile and validated malnutriti

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Eknäs, Sara, and Lydia Törner. "Honung som ett behanlingsalternativ av kronisk sår." Thesis, Hälsohögskolan, Högskolan i Jönköping, HHJ, Avd. för omvårdnad, 2018. http://urn.kb.se/resolve?urn=urn:nbn:se:hj:diva-38617.

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Sammanfattning Bakgrund: Svårläkta bensår drabbar en procent av Sveriges befolkning och påverkar den enskildes livskvalité negativt. När ett sår inte har läkt på 6 veckor klassificeras det som ett kroniskt sår. För att få ett sår att läkas ska det utredas vad det är för sår så rätt behandling sätts in som evidensbaserad omläggning, nutrition och avlastning som sjuksköterskan har ansvar för. Honung är ett alternativ till såromläggning av kroniska sår. Syfte: Syftet är att studera honungens effekt på sårläkning av kroniska sår. Metod: Allmän litteraturöversikt av 11 artiklar med kvantitativ ansa

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Abou, Issa Abdelfatah Shaban. "Effect of Oasis-Ultra Matrix on the Healing Rate of Stage IV Pressure Wounds." Wright State University / OhioLINK, 2016. http://rave.ohiolink.edu/etdc/view?acc_num=wright1464183028.

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Sample, Kate Ellen. "Registered Dietitians' Knowledge of Pressure Ulcers and the Role of Nutrition in Wound Care." Kent State University / OhioLINK, 2012. http://rave.ohiolink.edu/etdc/view?acc_num=kent1353392428.

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Backlund, Ingrid. "Evaluation of a selective media for the detection of gram-positive bacteria in leg ulcers and pressure wounds." Thesis, Uppsala universitet, Institutionen för kvinnors och barns hälsa, 2015. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-254614.

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Hard-to-heal ulcers are resource intensive due to the fact that they are difficult to treat and especially vulnerable to bacterial invasion. The bacterial culture contaminating these wounds often consist of several different bacterial organisms that originate from endogenous sources. Necrotic material in ischemic ulcers provide nutrition which support bacterial reproduction, increasing the risk of infection. Determining causative pathogen in infected ulcers proves to be difficult when culturing swab samples, however Staphylococcus aureus and hemolytic streptococci generally act as primary path

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Cheng, Qinglu. "Cost-effectiveness of guideline-based care for venous leg ulcers in Australia." Thesis, Queensland University of Technology, 2019. https://eprints.qut.edu.au/134462/1/Qinglu_Cheng_Thesis.pdf.

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This thesis investigated the cost-effectiveness of guideline-based care to manage patients with venous leg ulcers in the Australian setting. It showed that both the healthcare system and patients affected by venous leg ulcers would benefit from implementing and funding guideline-based care. This research provided important evidence to policy makers on the most efficient use of scarce health resources to manage venous leg ulcers. It is expected that these results will support changes to the reimbursement structure to increase access to guideline-based care for venous leg ulcers in Australia.

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Querio, Lagerberg Susanne, and Vangie Franzén. "Mer än ett sår : Att belysa sjuksköterskors erfarenheter av sårvård." Thesis, Högskolan i Halmstad, Akademin för hälsa och välfärd, 2016. http://urn.kb.se/resolve?urn=urn:nbn:se:hh:diva-31533.

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Sårvård är central omvårdnadsuppgift i sjuksköterskans profession som kräverspecifika kunskaper, förberedelser och tidsplanering vilket innebär behov av en radolika resurser men även kostnader för hälso- och sjukvården. Sjuksköterskanskunskap gällande prevention och sårvårdsbehandling utgör grunden förevidensbaserad sårvård med patientens personliga behov i fokus. Syftet var att belysasjuksköterskors erfarenheter av sårvård, och genomfördes som en systematisklitteraturstudie där resultatet utgjordes av åtta kvalitativa och två kvantitativavetenskapliga artiklar. I resultatet framkom fyra teman

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Cavassan, Nayara Rodrigues Vieira. "Caracterização de úlceras venosas através da expressão de proteínas presentes no exsudato inflamatório." Botucatu, 2016. http://hdl.handle.net/11449/136452.

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Orientador: Lucilene Delazari dos Santos<br>Coorientador: Luciana Patricia Fernandes Abbade<br>Resumo: Introdução: Úlceras venosas crônicas atingem até 4% da população mundial >65 anos, causando impacto socioeconômico, principalmente relacionado à diminuição da mobilidade e autoestima. O exsudato destas lesões, pode ser útil na identificação dos fatores envolvidos na reparação tecidual. Objetivos: Identificar proteínas expressas no exsudato de úlceras venosas, agrupando-as de acordo com suas principais funções, e correlancionando-as com variaveis clínicas e epidemiológicas. Métodos: Estudo clí

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Tang, Wan-yi Winnie, and 鄧韻怡. "Evidence-based guideline for using negative pressure wound therapy in diabetic foot care." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2011. http://hub.hku.hk/bib/B46582940.

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Charles, Hildegard E. "Venous ulcer repair and quality of life : a clinical study investigating three primary wound dressings using short stretch compression bandages." Thesis, Bucks New University, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.340926.

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Norgren, Sara, and Nils Bäcklund. "Omvårdnadspersonalens erfarenheter av sårbehandling och att vårda patienter med sår. : En litteraturstudie." Thesis, Umeå universitet, Institutionen för omvårdnad, 2016. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-131323.

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Titel: Omvårdnadspersonalens erfarenheter av sårbehandling och att vårda patienter med sår. Bakgrund: Sår är ett stort och komplext område och kunskapen har ökat sista decennierna vilket ställer nya krav på personalen. Genom att beskriva omvårdnadspersonalens erfarenheter kan utmaningar och problem synliggöras och detta kan ge möjligheter till att förbättra situationen för alla inblandade. Syfte: Att beskriva omvårdnadspersonalens erfarenheter av sårbehandling och att vårda patienter med sår. Metod: En litteraturstudie innehållandes 8 artiklar med kvalitativ ansats. Artiklarna granskades, anal

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Knight, Elizabeth Dawn. "Psychosocial Stress And Delayed Wound Healing: A Novel Approach To Increase Nursing Awareness And Knowledge." Diss., The University of Arizona, 2015. http://hdl.handle.net/10150/556602.

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Background: Chronic wounds are a significant health problem in various populations. Psychosocial stress is a lifestyle factor that has been shown to directly influence wound healing. Current findings support roles for assessment and reduction of psychosocial stress in the comprehensive management of chronic wounds, however, a gap remains between current research and current clinical practice. Purpose: To develop a novel method by which to educate nurses about the effects of psychosocial stress on wound healing while incorporating state-of-the-art technology that is sensitive to the needs of in

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Stupar, Dario. "Longitudinal assessment of inflammatory factors in samples from patients with chronic leg ulcers." Thesis, Queensland University of Technology, 2016. https://eprints.qut.edu.au/96580/1/Dario_Stupar_Thesis.pdf.

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Chronic leg ulcers are a major health problem that affect 1-3% of adults over 65 and are a financial burden on healthcare systems worldwide. In this study biochemical assays were performed on sequential samples collected from both healing and non-healing ulcers. The results demonstrated that inflammatory resolution was necessary for ulcers to heal. Interestingly, in healing ulcers, proteins associated with dampening inflammation did not change over time whilst those keeping the wound in an inflammatory state decreased, suggesting an alternative mechanism for resolution of inflammation.

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Rayment, Erin Alexis. "Investigation into the proteolytic activity in chronic wound fluid and development of a remediation strategy." Thesis, Queensland University of Technology, 2007. https://eprints.qut.edu.au/16564/1/Erin_Alexis_Rayment_Thesis.pdf.

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Chronic ulcers are an important and costly medical issue, causing their sufferers a large amount of pain, immobility and decreased quality of life. The common pathology in these chronic wounds is often characterised by excessive proteolytic activity, leading to the degradation of both the extracellular matrix, as well as key factors critical to the ulcer's ability to heal. As matrix metalloproteinases (MMPs), a large family of zinc-dependent endopeptidases, have been shown to have increased activity in chronic wound fluid (CWF), it was hypothesised that this specific proteolytic activity was d

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Rayment, Erin Alexis. "Investigation into the proteolytic activity in chronic wound fluid and development of a remediation strategy." Queensland University of Technology, 2007. http://eprints.qut.edu.au/16564/.

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Chronic ulcers are an important and costly medical issue, causing their sufferers a large amount of pain, immobility and decreased quality of life. The common pathology in these chronic wounds is often characterised by excessive proteolytic activity, leading to the degradation of both the extracellular matrix, as well as key factors critical to the ulcer's ability to heal. As matrix metalloproteinases (MMPs), a large family of zinc-dependent endopeptidases, have been shown to have increased activity in chronic wound fluid (CWF), it was hypothesised that this specific proteolytic activity was d

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Stewart, Ann Mary. "Investigation of predictors of recurrent venous leg ulcers and validation of a recurrence risk assessment tool." Thesis, Queensland University of Technology, 2019. https://eprints.qut.edu.au/133948/1/Ann_Stewart_Thesis_Redacted.pdf.

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Recurring venous leg ulcers are a serious health problem and it is difficult to predict when they are likely to recur. This research discovered new predictors of recurrence and found a checklist developed to assist in identifying the person's level of risk of recurrence, to be accurate more than 70% of the time. Prevention of recurrence is important and knowledge about the likelihood of these ulcers recurring can assist in preventing this from happening. This research has contributed knowledge to a topic which has had little previous research and has provided evidence to be further examined in

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Chikelu, Chukwuemeka W. "Smart-Release Cell Sheet Delivery System for Diabetic Wound Healing." University of Cincinnati / OhioLINK, 2016. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1470043822.

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Fernandez, Melissa Laura. "A longitudinal assessment of chronic wound fluid to detect biochemical indicators of healing." Thesis, Queensland University of Technology, 2010. https://eprints.qut.edu.au/48703/1/Melissa_Fernandez_Thesis.pdf.

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Chronic venous leg ulcers are a detrimental health issue plaguing our society, resulting in long term pain, immobility and decreased quality of life for a large proportion of sufferers. The frequency of these chronic wounds has led current research to focus on the wound environment to provide important information regarding the prolonged, fluctuated or static healing patterns of these wounds. Disruption to the normal wound healing process results in release of multiple factors in the wound environment that could correlate to wound chronicity. These biochemical factors can often be detected

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Vaalamo, Maarit. "Matrix metalloproteinases and their inhibitors in normal and aberrant wound repair : expression patterns of collagenases-1 and -3, stromelysins-1 and -2, matrilysin, metalloelastase and TIMPs-1, -2, -3 and -4 in healing cutaneous wounds and in chrome ulcers of the skin and the intestine." Helsinki : University of Helsinki, 2000. http://ethesis.helsinki.fi/julkaisut/laa/kliin/vk/vaalamo/.

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