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Artykuły w czasopismach na temat „United States vs. Germany”

Autor: Grafiati

Data publikacji: 27 lipca 2024

Data aktualizacji: 31 lipca 2025

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Hansen, Miriam, and Julia Mendzheritskaya. "How University Lecturers’ Display of Emotion Affects Students’ Emotions, Failure Attributions, and Behavioral Tendencies in Germany, Russia, and the United States." Journal of Cross-Cultural Psychology 48, no. 5 (2017): 734–53. http://dx.doi.org/10.1177/0022022117697845.

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In this study, we investigate whether the cultural-educational contexts in Russia, Germany, and the United States affect university students’ emotions, failure attributions, and behavioral tendencies after receiving negative achievement feedback from a lecturer. The 383 university students from Germany, Russia, and the United States participating in the study completed an online survey in which they read text vignettes of a university lecturer giving negative feedback to a student on his performance. We used a 2 × 3 × 3 experimental design to determine whether the negative feedback situation (

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Gadzhimuradova, Gyulnara, and Nemanja Vukcevic. "EU migration policy: policy of humanism vs threat to national security." Science. Culture. Society 29, no. 4 (2023): 54–64. http://dx.doi.org/10.19181/nko.2023.29.4.5.

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Uncontrolled migration sweeping Europe is a priority of the political leadership led by a number of European states such as France, Italy, as well as their allies in the United States. The climate crisis in Europe also plays an important role here, which can be resolved, according to Germany, with the help of future “new citizens” who arrived from countries in Africa and the Middle East, exclusively with a Muslim population. What are the migration and immigrant policies in EU countries? How is the immigration policy of European countries being transformed? A detailed analysis of the current st

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Salisbury, David, Jeffrey V. Lazarus, Nancy Waite, et al. "COVID-19 Vaccine Preferences in General Populations in Canada, Germany, the United Kingdom, and the United States: Discrete Choice Experiment." JMIR Public Health and Surveillance 10 (October 16, 2024): e57242. http://dx.doi.org/10.2196/57242.

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Background Despite strong evidence supporting COVID-19 vaccine efficacy and safety, a proportion of the population remains hesitant to receive immunization. Discrete choice experiments (DCEs) can help assess preferences and decision-making drivers. Objective We aim to (1) elicit preferences for COVID-19 vaccines in Canada, Germany, the United Kingdom, and the United States; (2) understand which vaccine attributes people there value; and (3) gain insight into the choices that different population subgroups make regarding COVID-19 vaccines. Methods Participants in the 2019nCoV-408 study were age

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Vokinger, Kerstin Noëlle, Paola Daniore, ChangWon C. Lee, Aaron S. Kesselheim, and Thomas J. Hwang. "Launch prices and price developments of cancer drugs in the United States and Europe." Journal of Clinical Oncology 38, no. 15_suppl (2020): 2006. http://dx.doi.org/10.1200/jco.2020.38.15_suppl.2006.

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2006 Background: Cancer drug costs are rising in the US and Europe. While drug manufacturers set prices without restriction in the US, European countries have regulations that allow national authorities to directly negotiate drug prices at launch and over time. We analyzed and compared the launch prices and price developments of cancer drugs in the US, Germany, Switzerland and England. Methods: We identified new drugs indicated to treat solid tumors in adults that were FDA-approved between 2009 and 2019 and had also been approved by the EMA and Swissmedic by 31 December 2019. Launch prices and

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Alba, Richard. "Bright vs. blurred boundaries: Second-generation assimilation and exclusion in France, Germany, and the United States." Ethnic and Racial Studies 28, no. 1 (2005): 20–49. http://dx.doi.org/10.1080/0141987042000280003.

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Walsh, Gianfranco. "Relationships among immigrant consumers' cultural orientation, innovativeness and opinion leadership." International Marketing Review 39, no. 1 (2021): 80–104. http://dx.doi.org/10.1108/imr-03-2021-0141.

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PurposeThis research examines the direct and indirect effects of immigrant consumers' (heritage vs host) cultural orientation on their opinion leadership, in relation to heritage versus host culture peers. In addition to examining the potential mediation of different exhibitions of innovativeness, the research tests whether the relative size of the immigrant population in a country might affect the relationship of consumers' cultural orientation and opinion leadership.Design/methodology/approachTests of the theoretical arguments rely on data from three samples of more than 1,000 consumers coll

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Rutenkröger, M., S. Wandke, J. Gempt, et al. "P21.02.A GERMAN TRANSLATION AND CROSS-CULTURAL ADAPTATION OF THE VESTIBULAR SCHWANNOMA QUALITY OF LIFE INDEX (VSQOL)." Neuro-Oncology 26, Supplement_5 (2024): v122. http://dx.doi.org/10.1093/neuonc/noae144.413.

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Abstract BACKGROUND Vestibular schwannomas (VSs) are benign tumors of the vestibulocochlear nerve that often cause significant neurological and functional impairment. Patient-reported outcomes, including quality of life (QoL), are essential for understanding the overall impact of VS and its treatment. This study aimed to translate and culturally adapt the Vestibular Schwannoma Quality of Life (VSQOL) Index into German to expand its relevance to German-speaking populations. MATERIAL AND METHODS We used a qualitative approach including translation and cognitive interviews with 10 patients who un

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Varnavskii, V. "Systemic Crisis of Euro-zone: Economics vs Politics." World Economy and International Relations, no. 11 (2012): 43–49. http://dx.doi.org/10.20542/0131-2227-2012-11-43-49.

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The main problem of the Euro-zone is not even the financial crisis combusted and not sovereign debts, but the absence of viable ideas how to preserve the institutional structure, managerial system and separation of powers between Brussels and national governments, which are designed in the Maastricht Treaty. No personalities are seen on the EU political landscape who could offer a realistic way of the crisis recovery, without economic and social shocks. European society, including its educated part, the elites, doesn't believe either in modern leaders, or in tools of crisis recovery suggested

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Wahl, Hans-Werner, Johanna Drewelies, Sandra Duezel, et al. "No Historical Change in Views on Aging and Their Correlates: Emerging Evidence From Germany and the United States." Innovation in Aging 5, Supplement_1 (2021): 286. http://dx.doi.org/10.1093/geroni/igab046.1111.

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Abstract To examine historical changes in views on aging, we compared matched cohorts of older adults within two independent studies that assessed differences across a two-decade interval, the Berlin Aging Studies (BASE, 1990/93 vs. 2017/18, each n = 256, Mage = 77) and the Midlife in the United States Study (MIDUS, 1995/96 vs. 2013/14, each n = 848, Mage = 67). Consistent across four different dimensions of individuals’ subjective views on aging (age felt, age appeared, desired age, attitudes towards own aging) in the Berlin Aging Studies and corroborated with subjective age felt in the MIDUS

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Kaufmann, Lutz, and Craig R. Carter. "International Supply Management Systems - The Impact of Price vs. Non-Price Driven Motives in the United States and Germany." Journal of Supply Chain Management 38, no. 3 (2002): 4–17. http://dx.doi.org/10.1111/j.1745-493x.2002.tb00131.x.

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Annunziata, Kathy, Nikoletta Sternbach, Hitomi Tanaka, et al. "The Impact of Multiple Myeloma on Care Partner Well-Being, Work Productivity, and Resource Use in the United States and Western Europe." Blood 144, Supplement 1 (2024): 3762. https://doi.org/10.1182/blood-2024-201802.

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BACKGROUND The impact of multiple myeloma (MM) extends beyond the affected patients themselves as care partners and family members also experience significant negative effects on their own quality of life (QOL), psychological well-being, and productivity. The objective of this study was to quantify the extent of this burden among care partners in both the United States (US) and Europe. METHODS This study analyzed data from the 2021 and 2022 National Health and Wellness Survey (NHWS) conducted in the US and European Union 4 (EU4; France, Germany, Italy, Spain) + United Kingdom (UK; ie, EU4+UK).

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Mahtani, Reshma, Alexander Niyazov, Bhakti Arondekar, et al. "BRCA1/2 Mutation Testing in Patients with HER2-Negative Advanced Breast Cancer: Real-World Data from the United States, Europe, and Israel." Cancers 14, no. 21 (2022): 5399. http://dx.doi.org/10.3390/cancers14215399.

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Poly(adenosine diphosphate-ribose) polymerase inhibitors are approved to treat patients harboring a germline breast cancer susceptibility gene 1 or 2 mutation (BRCA1/2mut) with human epidermal growth factor receptor 2—negative (HER2−) advanced breast cancer (ABC). This study evaluated differences in patient demographics, clinical characteristics, and BRCA1/2mut testing within the United States (US), European Union 4 (EU4; France, Germany, Italy, and Spain), and Israel in a real-world population of patients with HER2− ABC. Oncologists provided chart data from eligible patients from October 2019

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Ogdie, A., L. Schmerold, W. Tillett, R. Germino, J. C. Cappelleri, and P. Young. "AB0811 DEMOGRAPHIC, TREATMENT AND DISEASE CHARACTERISTICS OF PATIENTS WITH PSORIATIC ARTHRITIS RECEIVING TOFACITINIB IN THE UNITED STATES, FRANCE, GERMANY, ITALY, SPAIN AND THE UNITED KINGDOM." Annals of the Rheumatic Diseases 79, Suppl 1 (2020): 1707–8. http://dx.doi.org/10.1136/annrheumdis-2020-eular.982.

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Background:Tofacitinib is an oral JAK inhibitor for the treatment of psoriatic arthritis (PsA). The efficacy and safety of tofacitinib for PsA have been demonstrated in Phase 3 trials of up to 12 months’ (mos) duration.1,2Objectives:To describe demographic, treatment and disease characteristics of a sample of patients (pts) at initiation of tofacitinib for PsA in the United States (US), France, Germany, Italy, Spain and the United Kingdom (European Union Five; EU5).Methods:An online, retrospective medical chart review of de-identified pts treated with tofacitinib for PsA from the US and the EU

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Ernst, Nicole, Frank Esser, Sina Blassnig, and Sven Engesser. "Favorable Opportunity Structures for Populist Communication: Comparing Different Types of Politicians and Issues in Social Media, Television and the Press." International Journal of Press/Politics 24, no. 2 (2018): 165–88. http://dx.doi.org/10.1177/1940161218819430.

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The aim of this study is to explore favorable opportunity structures for populist communication of politicians in Western democracies. We analyze the content and style of 2,517 statements from 103 politicians from six countries (France, Italy, Germany, Switzerland, United Kingdom, and United States) who differ in their party affiliation (populist versus nonpopulist) and hierarchical position (backbencher vs. frontbencher). To learn more about their media strategies and chances of success, we investigate four communication channels (Facebook, Twitter, talk shows, and news media) that systematic

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Kim, Paul J., Siobhan Lookess, Christine Bongards, Leah Passmore Griffin, and Allen Gabriel. "Economic model to estimate cost of negative pressure wound therapy with instillation vs control therapies for hospitalised patients in the United States, Germany, and United Kingdom." International Wound Journal 19, no. 4 (2021): 888–94. http://dx.doi.org/10.1111/iwj.13689.

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Shores, Ryan, Katherine Fowler, John McDonough, Amy Suralis, Denise Scindele, and Tilman Müller-Wolff. "Rocuronium vs Succinylcholine: Emergency Airway Management of the COVID-19 Patient." Anesthesia eJournal 8, no. 2 (2021): 1–5. http://dx.doi.org/10.18776/wqxwhv19.

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Tracheal Intubation is routinely performed in many settings. Anesthesia providers are experts in this procedure. Determination for the best possible approach for tracheal intubation include patient and provider specific considerations. Severe acute respiratory syndrome-coronavirus-2 (SARS CoV-2) infection has led to the COVID-19 pandemic. SARS CoV-2 is a highly contagious RNA virus that has caused widespread infections, severe respiratory disease, and deaths. The purpose of this article is to describe the airway management currently recommended in Germany as well as the United States, the mult

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Kang, Yeong Seon, Eunji Huh, and Mi-Hee Lim. "Effects of Foreign Directors’ Nationalities and Director Types on Corporate Philanthropic Behavior: Evidence from Korean Firms." Sustainability 11, no. 11 (2019): 3132. http://dx.doi.org/10.3390/su11113132.

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Addressing the fact that there are few studies exploring the relationship between board characteristics and corporate social responsibility (CSR) in non-Western contexts, this study examines the relationship in South Korean corporate contexts. We concentrate on foreign directors as a board attribute, which is reported as a remarkable change in Korean corporate boards, and propose that foreign directors have different impacts on CSR investment depending on their nationality (Anglo-Americans vs. non-Anglo-Americans) and director types (insiders vs. outsiders). In detail, the presence of director

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Rodríguez Quijada, Mateo, and Svetlana Molkova. "URSS vs. EEUU, RDA vs. RFA: Guerra Fría en los Juegos Olímpicos de Verano (1952-1988) (U.S.S.R. vs. USA, GDR vs. FRG: Cold War at the Summer Olympics (1952-1988))." Retos, no. 33 (September 15, 2017): 37–39. http://dx.doi.org/10.47197/retos.v0i33.52809.

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Durante la Guerra Fría (1947-1991), las cuestiones geopolíticas determinaron el desarrollo del deporte internacional. Los Juegos Olímpicos se convirtieron en la arena de la lucha no solo deportiva sino política. Las victorias deportivas se utilizaban para mostrar la supremacia política, económica e ideológica de los países participantes. En la presente investigación se realiza un análisis de los medallistas de la Unión de Repúblicas Socialistas Soviéticas (URSS), los Estados Unidos (EEUU), la República Democrática Alemana (RDA) y la República Federal de Alemania (RFA) en los Juegos Olímpicos d

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Toth, Federico. "Integration vs separation in the provision of health care: 24 OECD countries compared." Health Economics, Policy and Law 15, no. 2 (2018): 160–72. http://dx.doi.org/10.1017/s1744133118000476.

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AbstractThis article proposes a classification of the different national health care systems based on the way the network of health care providers is organised. To this end, we present two rivalling models: on the one hand, the integrated model and, on the other, the separated model. These two models are defined based on five dimensions: (1) integration of insurer and provider; (2) integration of primary and secondary care; (3) presence of gatekeeping mechanisms; (4) patient's freedom of choice; and (5) solo or group practice of general practitioners. Each of these dimensions is applied to the

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Wood, Robert, Steve Fermer, Sulabha Ramachandran, Scott Baumgartner, and Robert Morlock. "Patients with Gout Treated with Conventional Urate-lowering Therapy: Association with Disease Control, Health-related Quality of Life, and Work Productivity." Journal of Rheumatology 43, no. 10 (2016): 1897–903. http://dx.doi.org/10.3899/jrheum.151199.

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Objective.Implications of inadequate gout control were assessed through health-related quality of life (HRQOL) and work productivity of patients with gout adequately controlled while taking conventional urate-lowering therapy (ULT) for ≥ 3 months vs those whose gout was inadequately controlled.Methods.Retrospective data were drawn from the Adelphi Disease Specific Programme (DSP), a cross-sectional survey of patients with gout in France, Germany, the United Kingdom, and the United States. Patients completed these questionnaires: EQ-5D (3L), Patient Reported Outcomes Measurement Information Sys

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Forrester, MB. "Bibliometric analysis of poison center-related research published in peer-review journals." Human & Experimental Toxicology 35, no. 7 (2015): 705–12. http://dx.doi.org/10.1177/0960327115598386.

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Poison centers advance knowledge in the field of toxicology through publication in peer-review journals. This investigation describes the pattern of poison center-related publications. Cases were poison center-related research published in peer-review journals during 1995–2014. These were identified through searching the PubMed database, reviewing the tables of contents of selected toxicology journals, and reviewing abstracts of various national and international meetings. The following variables for each publication were identified: year of publication, journal, type of publication (meeting a

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Zhou, Lihua, and Ying Wu. "Validation of the Chinese version of the Achievement Emotions Questionnaire–Elementary School." Social Behavior and Personality: an international journal 49, no. 5 (2021): 1–11. http://dx.doi.org/10.2224/sbp.10118.

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We developed the Chinese version of the Achievement Emotions Questionnaire–Elementary School (AEQ-ES), and tested its internal and external validity with a sample of 426 Chinese elementary school students aged between 6 and 10 years in three academic settings (class, homework, and test) of mathematics classes. The hierarchical model of the AEQ-ES for our Chinese sample was consistent with those obtained with samples of students in similar age groups in Italy, Germany, and the United States. We assessed the achievement emotions of enjoyment, boredom, and anxiety and found that girls (vs. boys)

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Cherry, James D. "The 112-Year Odyssey of Pertussis and Pertussis Vaccines—Mistakes Made and Implications for the Future." Journal of the Pediatric Infectious Diseases Society 8, no. 4 (2019): 334–41. http://dx.doi.org/10.1093/jpids/piz005.

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AbstractEffective diphtheria, tetanus toxoids, whole-cell pertussis (DTwP) vaccines became available in the 1930s, and they were put into routine use in the United States in the 1940s. Their use reduced the average rate of reported pertussis cases from 157 in 100 000 in the prevaccine era to <1 in 100 000 in the 1970s. Because of alleged reactions (encephalopathy and death), several countries discontinued (Sweden) or markedly decreased (United Kingdom, Germany, Japan) use of the vaccine. During the 20th century, Bordetella pertussis was studied extensively in animal model systems, and many

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Schluchter, Helena, Ahmad T. Nauman, Sabine Ludwig, Vera Regitz-Zagrosek, and Ute Seeland. "Quantitative and Qualitative Analysis on Sex and Gender in Preparatory Material for National Medical Examination in Germany and the United States." Journal of Medical Education and Curricular Development 7 (January 2020): 238212051989425. http://dx.doi.org/10.1177/2382120519894253.

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Background: Sex- and gender-based medicine (SGBM) should be a mandatory part of medical education. We compared the quantity and quality of sex- and gender-related content of e-learning materials commonly used by German and American medical students while preparing for national medical examinations. Methods: Quantitative, line-by-line analysis of the preparatory materials AMBOSS 2017 and USMLE Step 1 Lecture Notes (2017) by KAPLAN MEDICAL was performed between April and October 2017. Subjects were allocated to one of the three main fields: clinical subjects, behavioral and social science, and p

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de Paula Couto, M. Clara P., Helene Fung, Sylvie Graf, et al. "“OLDER ADULTS SHOULD…”: CROSS-NATIONAL DIFFERENCES IN ENDORSEMENT OF PRESCRIPTIVE AGE STEREOTYPES." Innovation in Aging 7, Supplement_1 (2023): 268. http://dx.doi.org/10.1093/geroni/igad104.0892.

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Abstract Normative expectations about how older adults should behave are known as prescriptive age stereotypes (or “prescriptive views of aging,” PVoA). Previous research has shown that endorsement of PVoA varies across age groups but has not yet examined the variability of PVoA endorsement across countries. Considering that context may influence the endorsement of PVoA, we investigated differences in endorsement reported by an international sample of adults (N = 2,902) from the Aging as Future study covering the age range from 40 to 90 years in five countries: Czechia, Germany, Hong Kong, Tai

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Scheer, Volker, David Valero, Elias Villiger, Thomas Rosemann, and Beat Knechtle. "The Impact of the COVID-19 Pandemic on Endurance and Ultra-Endurance Running." Medicina 57, no. 1 (2021): 52. http://dx.doi.org/10.3390/medicina57010052.

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Background and objectives: The COVID-19 outbreak has become a major health and economic crisis. The World Health Organization declared it a pandemic in March 2020, and many sporting events were canceled. Materials and Methods: We examined the effects of the COVID-19 pandemic on endurance and ultra-endurance running (UER) and analyzed finishes and events during the COVID-19 pandemic (observation period March 2020–October 2020) to the same time period pre-COVID-19 outbreak (March 2019–October 2019). Results: Endurance finishes decreased during the pandemic (459,029 to 42,656 (male: 277,493 to 25

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Scheer, Volker, David Valero, Elias Villiger, Thomas Rosemann, and Beat Knechtle. "The Impact of the COVID-19 Pandemic on Endurance and Ultra-Endurance Running." Medicina 57, no. 1 (2021): 52. http://dx.doi.org/10.3390/medicina57010052.

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Background and objectives: The COVID-19 outbreak has become a major health and economic crisis. The World Health Organization declared it a pandemic in March 2020, and many sporting events were canceled. Materials and Methods: We examined the effects of the COVID-19 pandemic on endurance and ultra-endurance running (UER) and analyzed finishes and events during the COVID-19 pandemic (observation period March 2020–October 2020) to the same time period pre-COVID-19 outbreak (March 2019–October 2019). Results: Endurance finishes decreased during the pandemic (459,029 to 42,656 (male: 277,493 to 25

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Larose, Martin. "Kaim, Markus et Ursula Lehmkuhl (dir.), In Search of a New Relationship. Canada, Germany, and the United States, Wiesbaden, vs Verla für Sozialwissenschaften, 2005, 160 p." Études internationales 37, no. 4 (2006): 665. http://dx.doi.org/10.7202/014651ar.

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Rychlowska, Magdalena, Yuri Miyamoto, David Matsumoto, et al. "Heterogeneity of long-history migration explains cultural differences in reports of emotional expressivity and the functions of smiles." Proceedings of the National Academy of Sciences 112, no. 19 (2015): E2429—E2436. http://dx.doi.org/10.1073/pnas.1413661112.

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A small number of facial expressions may be universal in that they are produced by the same basic affective states and recognized as such throughout the world. However, other aspects of emotionally expressive behavior vary widely across culture. Just why do they vary? We propose that some cultural differences in expressive behavior are determined by historical heterogeneity, or the extent to which a country’s present-day population descended from migration from numerous vs. few source countries over a period of 500 y. Our reanalysis of data on cultural rules for displaying emotion from 32 coun

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Patel, K. V., P. Salmon, I. Marin-Jiménez, et al. "P416 The impact of remission on healthcare resource utilisation and costs amongst patients with inflammatory bowel disease in France, Germany, Italy, Spain, and the United Kingdom." Journal of Crohn's and Colitis 17, Supplement_1 (2023): i544—i546. http://dx.doi.org/10.1093/ecco-jcc/jjac190.0546.

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Abstract Background Crohn’s disease (CD) and ulcerative colitis (UC) are chronic inflammatory bowel diseases (IBD) with increasing healthcare resource utilisation (HCRU) and associated costs. Optimal management of CD and UC aims to induce and maintain remission which may subsequently lower HCRU and costs. This study reports on the potential impact on HCRU and associated direct HCRU costs (excluding drug costs) from achieving CD or UC remission in France, Germany, Italy, Spain and the United Kingdom (EU5). Methods Data were drawn from an Adelphi Real World IBD Disease Specific ProgrammeTM, a po

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Norman, John G., Stephen Brealey, Ada Keding, David Torgerson, and Amar Rangan. "Does time to surgery affect patient-reported outcome in proximal humeral fractures? A subanalysis of the PROFHER randomized clinical trial." Bone & Joint Journal 102-B, no. 1 (2020): 33–41. http://dx.doi.org/10.1302/0301-620x.102b1.bjj-2020-0546.r1.

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Aims The aim of this study was to explore whether time to surgery affects functional outcome in displaced proximal humeral fractures Methods A total of 250 patients presenting within three weeks of sustaining a displaced proximal humeral fracture involving the surgical neck were recruited at 32 acute NHS hospitals in the United Kingdom between September 2008 and April 2011. Of the 125 participants, 109 received surgery (fracture fixation or humeral head replacement) as per randomization. Data were included for 101 and 67 participants at six-month and five-year follow-up, respectively. Oxford S

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Patel, Rahul, Krishna Sajeev, Vani Sojitra, et al. "EVOLVING LANDSCAPE OF INFLAMMATORY BOWEL DISEASE IN G20 NATIONS (1990-2019): A COMPREHENSIVE GLOBAL ASSESSMENT." Inflammatory Bowel Diseases 30, Supplement_1 (2024): S31. http://dx.doi.org/10.1093/ibd/izae020.069.

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Abstract BACKGROUND As pivotal players in the global economy, the G20 countries not only lead in economic dynamics but also in health challenges. Recent data reveals an escalating burden of Inflammatory Bowel Disease (IBD) in these nations. Understanding this trend is crucial to frame healthcare strategies and ensure the well-being of a significant portion of the global population. METHOD We employed data on IBD prevalence, incidence, mortality, and DALYs for G20 countries from the Global Burden of Disease (GBD) 2019 study. Using standardized statistical techniques, we analyzed by age, sex, ye

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Hossain, Arif. "Peace, Conflict and Resolution (Good vs. Evil)." Bangladesh Journal of Bioethics 4, no. 1 (2013): 9–19. http://dx.doi.org/10.3329/bioethics.v4i1.14264.

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The immense structural inequalities of the global social /political economy can no longer be contained through consensual mechanisms of state control. The ruling classes have lost legitimacy; we are witnessing a breakdown of ruling-class hegemony on a world scale. There is good and evil among mankind; thus it necessitates the conflict between the good and evil on Earth. We are in for a period of major conflicts and great upheavals. It's generally regarded that Mencius (c.371- c.289 B.C) a student of Confucianism developed his entire philosophy from two basic propositions: the first, that Man's

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Butler, Marcus O., Caroline Robert, Sylvie Negrier, et al. "ILLUMINATE 301: A randomized phase 3 study of tilsotolimod in combination with ipilimumab compared with ipilimumab alone in patients with advanced melanoma following progression on or after anti-PD-1 therapy." Journal of Clinical Oncology 37, no. 15_suppl (2019): TPS9599. http://dx.doi.org/10.1200/jco.2019.37.15_suppl.tps9599.

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TPS9599 Background: Tilsotolimod (IMO-2125) is a Toll-like receptor (TLR) 9 agonist with potent immunostimulating activity. In an ongoing Phase 1/2 clinical study in patients with advanced melanoma who progressed on or after anti-PD-1 therapy (NCT02644967), intratumoral (IT) tilsotolimod with ipilimumab was well-tolerated, demonstrating durable responses (including complete response > 21 months), dendritic cell activation, type I interferon response, CD8+ T-cell proliferation in responders, and an abscopal effect. Methods: ILLUMINATE 301 (NCT03445533) is a randomized phase 3 global, multi-c

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Malin, Joel R., Chris Brown, Georgeta Ion, et al. "World-wide barriers and enablers to achieving evidence-informed practice in education: what can be learnt from Spain, England, the United States, and Germany?" Humanities and Social Sciences Communication 7, no. 99 (2020): 2–14. https://doi.org/10.5281/zenodo.4041563.

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A global push exists to bolster the connections between research and practice in education. However, fostering evidence-informed practice (EIP) has proven challenging. Indeed, this ‘problem’ requires simultaneously attending to multiple aspects/levels of education systems, and to the contexts within which they reside. As such, comparative analyses using systems approaches hold potential for achieving context-specific insights regarding how to foster EIP. However, such analyses have been scarce, and what research does exist has generally been limited relative to methods and theory.

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Naujokaitis, Tadas, Ramin Khoramnia, Grzegorz Łabuz, Chul Young Choi, Gerd U. Auffarth, and Tamer Tandogan. "Imaging Function and Relative Light Transmission of Explanted Opacified Hydrophilic Acrylic Intraocular Lenses." Diagnostics 13, no. 10 (2023): 1804. http://dx.doi.org/10.3390/diagnostics13101804.

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We evaluated the influence of intraocular lens (IOL) opacification on the optical performance of explanted hydrophilic acrylic IOLs. We performed a laboratory analysis of 32 Lentis LS-502-1 (Oculentis GmbH, Berlin, Germany) IOLs, explanted due to opacification, in comparison with six clear unused samples of the same IOL model. Using an optical bench setup, we obtained modulation transfer function (MTF), Strehl ratio, two-dimensional MTF, and United States Air Force (USAF) chart images. In addition, we assessed light transmission through the IOLs. The MTF values of opacified IOLs at 3-mm apertu

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Trautmann-Grill, Karolin, Nils Kossack, Laila El Hadad, et al. "Real-World Use of Carfilzomib for the Treatment of Relapsed/Refractory Multiple Myeloma in Germany: Once-Weekly and Twice-Weekly Administration Schedules." Blood 144, Supplement 1 (2024): 7826. https://doi.org/10.1182/blood-2024-198394.

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Introduction: The doublet therapy of carfilzomib (CFZ) in combination with dexamethasone is commonly used to treat multiple myeloma (MM) in clinical practice and is used as a comparator in several randomized clinical trials. It is approved for once-weekly (70 mg/m2) and twice-weekly (56 mg/m2) administration in the United States (US), although only the twice-weekly dose is approved in the European Union. There is limited consensus on the efficacy and safety of the CFZ dosing schedules (A.R.R.O.W. trial; Moreau P, et al. Lancet Oncol 2018;19:953-964); however, clinical practice indicates that t

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Peyrin-Biroulet, L., R. Ungaro, D. T. Rubin, et al. "P683 Economic impact of achieving mucosal healing on UC-related hospitalisations and work productivity in patients with moderately to severely active UC: A post-hoc analysis of risankizumab Phase 2b/3 trials." Journal of Crohn's and Colitis 18, Supplement_1 (2024): i1298—i1299. http://dx.doi.org/10.1093/ecco-jcc/jjad212.0813.

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Abstract Background The value of endoscopic-histologic healing is incompletely understood, and definitions are variable. We assessed the clinical and economic value of achieving mucosal healing in patients with ulcerative colitis (UC) by evaluating the relationship of histologic-endoscopic mucosal improvement (HEMI) and subsequent UC-related hospitalisation and work productivity, and associated costs in the United States (US); United Kingdom (UK); and France, Germany, Italy, and Spain (EU4). Methods Data from the risankizumab (RZB) INSPIRE induction (NCT03398148) and COMMAND maintenance (NCT03

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Fendler, Wolfgang Peter, Madeleine J. Karpinski, Sebastian Hoberück, et al. "Prostate cancer risk groups by PSMA-PET PROMISE (PPP): Results from an international multi-center registry study." Journal of Clinical Oncology 43, no. 5_suppl (2025): 266. https://doi.org/10.1200/jco.2025.43.5_suppl.266.

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266 Background: We previously established prognostic nomograms of PSMA-PET standardized by Prostate Cancer Molecular Imaging Standardized Evaluation (PROMISE) criteria in a large single-center cohort. Now, we reassess the PSMA-PET PROMISE (PPP) prognostic nomograms in a large international multi-center registry study with overall survival follow-up. Methods: We included patients with histologically proven prostate cancer who underwent PSMA-PET at 20 hospitals in Germany, Italy, Sweden, Netherlands, Belgium, Slovakia, Austria, United States and Australia between 2014 and 2021. PSMA-PET was stan

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Hossain, Arif. "Peace, Conflict and Resolution (Good vs. Evil) Part 2." Bangladesh Journal of Bioethics 4, no. 2 (2013): 9–21. http://dx.doi.org/10.3329/bioethics.v4i2.16372.

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The immense structural inequalities of the global social /political economy can no longer be contained through consensual mechanisms of state control. The ruling classes have lost legitimacy; we are witnessing a breakdown of ruling-class hegemony on a world scale. There is good and evil among mankind; thus it necessitates the conflict between the good and evil on Earth. We are in for a period of major conflicts and great upheavals. It's generally regarded that Mencius (c.371-c.289 B.C) a student of Confucianism developed his entire philosophy from two basic propositions: the first, that Man's

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Sikirica, M., J. Lynch, J. Kershaw, R. Lukanova, S. Baker, and G. Milligan. "P246 Persistent burden of disease in patients with Crohn’s disease treated with biologic therapy: results from a real-world survey in the United States (US), France, Germany, Italy, Spain, and United Kingdom (5EU)." Journal of Crohn's and Colitis 16, Supplement_1 (2022): i292—i293. http://dx.doi.org/10.1093/ecco-jcc/jjab232.373.

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Abstract Background Crohn’s disease (CD) requires life-long disease management. The study objective was to investigate the burden of CD in patients who have only partially responded to biologic therapy. Methods Data were drawn from two waves (Nov 2014-Mar 2015; Sep 2017-Jan 2018) of the Adelphi Inflammatory Bowel Disease (IBD) Disease Specific Programme™, a point-in-time survey of gastroenterologists (GEs) and their IBD patients, in the US, and 5EU. GEs completed a physician-reported questionnaire (PRF) for 5–10 consecutively consulting patients with CD, covering demographics, clinical charact

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Diel, Roland, and Niklas Lampenius. "Cost-benefit analysis of VKA versus NOAC treatment in German patients with atrial fibrillation utilizing patient self-testing." Journal of Health Economics and Outcomes Research 6, no. 3 (2019): 142–59. http://dx.doi.org/10.36469/9774.

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Objectives: This study quantified the burden of hypoxic respiratory failure (HRF)/persistent pulmonary hypertension of newborn (PPHN) in preterm and term/near-term infants (T/NTs) by examining health care resource utilization (HRU) and charges in the United States. Methods: Preterms and T/NTs (≤34 and >34 weeks of gestation, respectively) having HRF/PPHN, with/without meconium aspiration in inpatient setting from January 1, 2011-October 31, 2015 were identified from the Vizient database (first hospitalization=index hospitalization). Comorbidities, treatments, HRU, and charges during index h

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Nagapurkar, Prashant, Naushita Sharma, Susana Garcia, and Sachin Nimbalkar. "Evaluating Acoustic vs. AI-Based Satellite Leak Detection in Aging US Water Infrastructure: A Cost and Energy Savings Analysis." Smart Cities 8, no. 4 (2025): 122. https://doi.org/10.3390/smartcities8040122.

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The aging water distribution system in the United States, constructed mainly during the 1970s with some pipes dating back 125 years, is experiencing significant deterioration leading to substantial water losses. Along with the potential for water loss savings, improvements in the distribution system by using leak detection technologies can create net energy and cost savings. In this work, a new framework has been presented to calculate the economic level of leakage within water supply and distribution systems for two primary leak detection technologies (acoustic vs. satellite). In this work, a

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Dick, Wolfgang F. "Anglo-American vs. Franco-German Emergency Medical Services System." Prehospital and Disaster Medicine 18, no. 1 (2003): 29–37. http://dx.doi.org/10.1017/s1049023x00000650.

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AbstractIt has been stated that the Franco-German Emergency Medical Services System (FGS) has considerable drawbacks compared to the Anglo-American Emergency Medical Services System (AAS):1. The key differences between the AAS and the FGS are that in the AAS, the patients is brought to the doctor, while in the FGS, the doctor is brought to the patient.2. In the FGS, patients with urgent conditions usually are evaluated and treated by general practitioners in their offices or at the patient`s home; initially, very few approach an emergency department.3. Emergency patients with life-threatening

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Broughton, Edward I., Jürgen E. Gschwend, J. Alfred Witjes, et al. "Use of perioperative treatment (tx) among patients (pts) undergoing radical resection (RR) for muscle-invasive urothelial cancer (MIUC) in France, Germany, Italy, Spain, the United Kingdom, the United States, Canada, China, and Japan." Journal of Clinical Oncology 40, no. 6_suppl (2022): 467. http://dx.doi.org/10.1200/jco.2022.40.6_suppl.467.

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467 Background: Cisplatin-based neoadjuvant chemotherapy (NAC) followed by RR is the standard of care in cisplatin-eligible pts with MIUC. Adjuvant chemotherapy (AC) with cisplatin-based tx may be offered to those not given NAC. The unmet need this survey tried to evaluate is the post-RR burden of disease, quality of life (QoL) and perioperative tx patterns among MIUC pts. Methods: Real-world descriptive data were drawn from Adelphi’s MIUC Disease-Specific Programme: A point-in-time survey conducted with clinical/medical oncologists/urologists and their pts in 9 countries between January and J

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Ijaz, M. Khalid, Raymond W. Nims, Sarah de Szalay, and Joseph R. Rubino. "Soap, water, and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2): an ancient handwashing strategy for preventing dissemination of a novel virus." PeerJ 9 (September 17, 2021): e12041. http://dx.doi.org/10.7717/peerj.12041.

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Public Health Agencies worldwide (World Health Organization, United States Centers for Disease Prevention & Control, Chinese Center for Disease Control and Prevention, European Centre for Disease Prevention and Control, etc.) are recommending hand washing with soap and water for preventing the dissemination of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections. In this review, we have discussed the mechanisms of decontamination by soap and water (involving both removal and inactivation), described the contribution of the various components of formulated soaps to perfor

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Cella, D., M. D. Michaelson, J. C. Cappelleri та ін. "Quality of life (QOL) with sunitinib versus interferon-alfa (IFN-α) as first-line therapy in patients with metastatic renal cell carcinoma (mRCC): Final results". Journal of Clinical Oncology 27, № 15_suppl (2009): 6529. http://dx.doi.org/10.1200/jco.2009.27.15_suppl.6529.

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6529 Background: In an international, randomized phase 3 trial (Figlin et al, ASCO. 2008), sunitinib showed superior progression-free survival (the primary endpoint) and objective response rate over IFN-α (11 vs. 5 mo and 47% vs. 12%, respectively; p < 0.000001) as first-line mRCC therapy, with a median overall survival of more than 2 years. Here, we report the final health-related QOL results from this trial. Methods: 750 treatment-naïve mRCC patients were randomized 1:1 to receive sunitinib 50 mg orally once-daily in recurring cycles of 4 weeks on drug and 2 weeks off or IFN-α 9 MU subcut

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Gottschalk, Zachary, Mary Weber Redman, Kelsey K. Baker, et al. "Comparison of risk factors, treatment strategy, and outcomes of early- vs. older-onset colorectal cancer within the prospective ColoCare study." Journal of Clinical Oncology 43, no. 4_suppl (2025): 95. https://doi.org/10.1200/jco.2025.43.4_suppl.95.

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95 Background: The incidence of colorectal cancer among young adults aged 20-49 has continually increased in recent decades. Early-onset colorectal cancer (EOCRC) patients are more likely to be diagnosed at a more advanced stage of disease, have hereditary cancer syndromes, and have different molecular pathological features of disease than later-onset patients. Herein we compare the risk factors, treatment approaches, and responses to treatment of early-onset versus later-onset colorectal cancer within. Methods: The ColoCare Study is a prospective cohort enrolling individuals diagnosed with pr

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Corn, Tim, Peter Ogram, and Tina Doede. "Veno-Occlusive Disease/Sinusoidal Obstruction Syndrome: Diagnostic Patterns Among United States and European Union Hematologists and Oncologists Managing Patients Receiving Stem Cell Transplantation." Blood 126, no. 23 (2015): 4732. http://dx.doi.org/10.1182/blood.v126.23.4732.4732.

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Abstract Introduction Hepatic veno-occlusive disease, also called sinusoidal obstruction syndrome (VOD/SOS), is an unpredictable, potentially fatal complication of hematopoietic stem cell transplantation (HSCT) and high-dose chemotherapy. The VOD/SOS pathologic cascade is initiated by endothelial and hepatocyte damage. VOD/SOS is usually diagnosed using Baltimore criteria (≤21 days post transplant: bilirubin >2 mg/dL, plus 2 or more of hepatomegaly, ascites, and weight gain ≥5%) or modified Seattle criteria (≤20 days post transplant: 2 or more of bilirubin >2 mg/dL, hepatomegaly or right

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Li, Miriam, Nathan Barreth, Kim Cheema, et al. "NOVEL URINARY BIOMARKER MODEL FOR DIFFERENTIATING LUPUS NEPHRITIS FROM ANCA-ASSOCIATED VASCULITIS." Journal of Rheumatology 52, Suppl 1 (2025): 151.2–152. https://doi.org/10.3899/jrheum.2025-0390.pv126.

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PV126 / #511Poster Topic:AS15 - Lupus Nephritis-ClinicalBackground/PurposeUrinary complement activation products (uCAP) and soluble CD163 (usCD163) are promising biomarkers that reflect active renal inflammation in lupus nephritis (LN). However, these urinary proteins alone are not specific to LN since they can be elevated in other disorders including ANCA-associated vasculitis (AAV). The goal of this study was to develop a model that can accurately differentiate between LN vs. AAV using a combination of uCAP, usCD163, and urine protein-creatinine ratio (UPCR) levels.MethodsWe included patient

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