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Rozprawy doktorskie na temat „Vascular pain”

Autor: Grafiati

Data publikacji: 2 czerwca 2025

Data aktualizacji: 31 lipca 2025

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1

Hansrani, Vivak. "Exploring a vascular cause for chronic pelvic pain in women." Thesis, University of Manchester, 2017. https://www.research.manchester.ac.uk/portal/en/theses/exploring-a-vascular-cause-for-chronic-pelvic-pain-in-women(b0cd0418-1e6d-428b-89eb-e4951c796e12).html.

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Objectives: Pelvic vein incompetence (PVI) has been suggested as a cause for chronic pelvic pain. The overall objective of this thesis is to determine how PVI affects women, identify suitable methods of diagnosis and provide evidence regarding its association with chronic pelvic pain. This thesis will also evaluate the evidence behind its treatment. Methods: Four observation studies were completed during this thesis. A characterisation study encompassing 120 participants was performed to determine symptoms commonly experienced by women with PVI. Two observation studies analysed the ability of

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Vassy, W. Matthew. "Adherence of sickle erythrocytes to vascular endothelium : therapeutic screening and the pathophysiology of pain crisis." Thesis, Georgia Institute of Technology, 1996. http://hdl.handle.net/1853/10030.

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Nogueira, Mariana. "Gênero: representação cognitiva e enfrentamento da dor central decorrente de acidente vascular encefálico." Universidade de São Paulo, 2011. http://www.teses.usp.br/teses/disponiveis/5/5138/tde-04052011-170125/.

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A dor central decorrente de acidente vascular encefálico (AVE) por ser intensa e persistente, gera repercussões físicas, sociais, psicológicas e financeiras. Foram evidenciadas diferenças de gênero quanto aos aspectos sensoriais, fisiológicos, afetivos, sociais, culturais, cognitivos e comportamentais relacionados à dor. No entanto, há poucas pesquisas sobre gênero e dor e não existe consenso sobre diferenças entre homens e mulheres quanto à representação cognitiva e processos de enfrentamento da dor. Os objetivos da pesquisa foram: identificar e comparar os processos de enfrentamento de homen

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Kolotyluk, Danny Robert. "Mechanical stenosis of the maxillary artery in the infratemporal fossa, an etiology of craniomandibular pain and vascular headache." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1997. http://www.collectionscanada.ca/obj/s4/f2/dsk3/ftp05/mq22616.pdf.

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Oliveira, Rogério Adas Ayres de. "O efeito da estimulação magnética transcraniana repetitiva do córtex pré-frontal dorsolateral esquerdo na dor central decorrente de acidente vascular cerebral." Universidade de São Paulo, 2016. http://www.teses.usp.br/teses/disponiveis/5/5138/tde-10032017-085905/.

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Introdução e objetivos: A dor central pós-acidente vascular cerebral (DCAVC) é causada pela lesão vascular de estruturas somatossensitivas encefálicas e comumente refratária aos tratamentos farmacológicos disponíveis atualmente. A estimulação magnética transcraniana repetitiva (EMTr) do córtex pré-frontal dorsolateral (CPFDL) pode alterar o limiar da dor térmica de indivíduos saudáveis e exercer efeito analgésico na dor aguda pós-operatória e em doentes com síndrome fibromiálgica. No entanto, seu efeito na dor neuropática e na DCAVC, em particular, ainda não foi avaliado. O objetivo do present

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Hedin, Hannah, and Elin Alpadie. "UPPLEVELSER AV PERIFER VASKULÄR INSUFFICIENS -en litteraturöversikt." Thesis, Malmö högskola, Fakulteten för hälsa och samhälle (HS), 2011. http://urn.kb.se/resolve?urn=urn:nbn:se:mau:diva-26363.

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Perifer vaskulär insufficiens innebär arteriell och/eller venös cirkulationssvikt i nedre extremiteter, vilket kan förorsaka bensår. Vaskulär insufficiens i benen är ett ökande hälsoproblem som ofta är ett mycket smärtsamt tillstånd och kan ha stora konsekvenser för den drabbade i dennes dagliga liv. Litteraturöversikt valdes som metod för att besvara syftet; att beskriva forskning om patienters upplevelser av hur perifer vaskulär insufficiens i de nedre extremiteterna påverkar det dagliga livet. Detta utifrån Carnevalis omvårdnadsteori om dagligt liv funktionellt hälsotillstånd. Stora inskrän

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Dharmalingam, Backialakshmi [Verfasser]. "Immune mediated disturbances of bone, connective tissue and vascular metabolism in Complex Regional Pain Syndrome (CRPS) : a new pathogenic mechanism of therapeutic relevance / Backialakshmi Dharmalingam." Gießen : Universitätsbibliothek, 2015. http://d-nb.info/1076980287/34.

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Giot, Jean-Philippe. "Implication des cytokines inflammatoires dans l'angiodermite nécrotique." Thesis, Poitiers, 2013. http://www.theses.fr/2013POIT1406/document.

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L'angiodermite nécrotique ou "Hypertensive Leg Ulcer" (HLU) est un ulcère de jambe inflammatoire de traitement difficile, associé à une hypertension artérielle chronique. La douleur est très importante et nécessite l'utilisation de la morphine pour soulager les patients. Notre objectif était d'analyser les caractéristiques de l'inflammation et d'étudier son implication dans la physiopathologie de la nécrose cutanée. La peau inflammatoire est le siège d'un infiltrat composé de macrophages et de lymphocytes. L'épiderme et les cellules vasculaires lisses des microvaisseaux présentent des troubles

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Amadera, João Eduardo Daud. "Avaliação do tratamento da dor crônica em ombros de hemiplégicos com bloqueio transforaminal de C6: um estudo duplo cego randomizado sham-controlado." Universidade de São Paulo, 2013. http://www.teses.usp.br/teses/disponiveis/5/5144/tde-02012014-174753/.

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Objetivo: A taxa de falha terapêutica para dor crônica em ombros de hemiplégicos (DOH) pós acidente vascular encefálico (AVE) é significante. Diversas abordagens terapêuticas têm sido propostas, porém os resultados dos estudos que as têm investigado demostram resultados controversos. Objetivo: Elaborar um protocolo para avaliar a eficácia da injeção de dexametasona via transforaminal (TF) na DOH. Métodos: Ensaio clínico randomizado, controlado por placebo, com cegamento de pacientes e avaliadores de desfecho. Ambiente clínico: Departamento de Ortopedia e Neurocirurgia de um hospital terciário.

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Caro, Camila Caminha. "Independência e cognição pós-AVC e sua relação com a sobrecarga, dor e qualidade de vida dos cuidadores familiares." Universidade Federal de São Carlos, 2015. https://repositorio.ufscar.br/handle/ufscar/6898.

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Made available in DSpace on 2016-06-02T20:44:16Z (GMT). No. of bitstreams: 1 6638.pdf: 8365258 bytes, checksum: 8a9cc4ae2287b1d9ed7ad4effcdf6a13 (MD5) Previous issue date: 2015-02-20<br>Stroke is one of the chronic diseases that cause impairment, mainly motor and cognitive ones, which can compromise the functional capacity, making the subject dependent of care. In this context, it is family s responsibility to take care for the ill individual, assisting him in several everyday activities. The possibility of being a caregiver causes many changes in family dynamics, in the roles and in people'

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Hagnelius, Nils-Olof. "Vascular mechanisms in dementia with special reference to folate and fibrinolysis." Doctoral thesis, Örebro universitet, Hälsoakademin, 2009. http://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-7785.

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The aim of this thesis was to study the biomarker homocysteine and other novel potential vascular risk factors for dementia. In an out-patient based study of a cohort of 926 consecutive subjects referred to our Memory Unit during 1996―2000, serum-folate was lower and total plasma homocysteine (tHcy) and serum methyl malonate were higher in subjects being prescribed with B12. In the subgroup diagnosed with dementia and with a positive family history of dementia, tHcy was higher than in the subgroup diagnosed as non-demented. It is necessary to supplement subjects with vitamin B12 deficiency wit

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Mansfield, Michael William. "The interaction of genetic and environmental vascular risk markers in patients with non-insulin-dependent diabetes mellitus and their first degree relatives." Thesis, University of Oxford, 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.388894.

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Akouo, Lambert. "Épidémiologie des démences vasculaires : prévalence chez les sujets de plus de 65 ans, vivant au domicile et en institution, variation de la prévalence selon l'âge, le sexe, la zone d'habitation, le niveau d'éducation : données du projet Paquid et Pavin." Bordeaux 2, 1993. http://www.theses.fr/1993BOR2M002.

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14

Moreau, Nathan. "Rôle de l'altération de la perméabilité vasculaire endoneurale dans la genèse des douleurs neuropathiques périphériques post-traumatiques : Implications des voies de signalisation TLR4, Sonic Hedgehog et Wnt/ß-caténine." Thesis, Paris 6, 2017. http://www.theses.fr/2017PA066039/document.

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A la suite d'une lésion nerveuse périphérique, de multiples altérations cellulaires et moléculaires participent à la régénération physiologique du nerf, mais induisent dans certains cas le développement d'une cicatrisation dysfonctionnelle et l'apparition d'une douleur neuropathique chronique. La régulation de la perméabilité vasculaire endoneurale du nerf lésé joue un rôle essentiel dans ces phénomènes de cicatrisation nerveuse, via notamment l'infiltration locale d'immunocytes. L'objectif de ce travail était d'étudier le rôle spécifique de l'altération de la barrière hémato-nerveuse (BHN) au

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Meade, Eliza. "Hypoxic Regulation of VEGF and PAI-1 Expression by HIF-1[alpha] and HIF-2[alpha] in First Trimester Trophoblasts." Yale University, 2006. http://ymtdl.med.yale.edu/theses/available/etd-06282006-115727/.

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Preeclampsia results from incomplete trophoblast invasion of the spiral arteries during early pregnancy. Vascular endothelial growth factor (VEGF) and plasminogen activator inhibitor-1 (PAI-1) are critical factors involved in angiogenesis, invasion and hemostasis at the maternal-fetal interface. Both factors are transcriptionally regulated by hypoxia inducible factor (HIF), a heterodimeric complex consisting of HIF-1[beta] and either HIF-1[alpha] or -2[alpha] whose specificity or redundancy in gene regulation is cell-type specific. This study uses siRNA technology to dissect the mechanisms of

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Grimsley, Philip George Medical Sciences Faculty of Medicine UNSW. "Receptor mediated catabolism of plasminogen activators." Awarded By:University of New South Wales. Medical Sciences, 2009. http://handle.unsw.edu.au/1959.4/44489.

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Humans have two plasminogen activators (PAs), tissue-type plasminogen activator (tPA) and urokinase-type plasminogen activator (uPA), which generate plasmin to breakdown fibrin and other barriers to cell migration. Both PAs are used as pharmaceuticals but their efficacies are limited by their rapid clearance from the circulation, predominantly by parenchymal cells of the liver. At the commencement of the work presented here, the hepatic receptors responsible for mediating the catabolism of the PAs were little understood. tPA degradation by hepatic cell lines was known to depend on the forma

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17

Pereira, Ana Júlia dos Reis. "Role of the vascular endohelial growth factor in bladder pain syndrome/interstitial cystitis." Master's thesis, 2012. https://repositorio-aberto.up.pt/handle/10216/65132.

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Pereira, Ana Júlia dos Reis. "Role of the vascular endohelial growth factor in bladder pain syndrome/interstitial cystitis." Dissertação, 2012. https://repositorio-aberto.up.pt/handle/10216/65132.

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"Applications of Miniaturized Ultrasound Powered Wireless Nerve Stimulators for Pain Management." Master's thesis, 2014. http://hdl.handle.net/2286/R.I.27502.

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abstract: Peripheral Vascular Disease (PVD) is a debilitating chronic disease of the lower extremities particularly affecting older adults and diabetics. It results in reduction of the blood flow to peripheral tissue and sometimes causing tissue damage such that PVD patients suffer from pain in the lower legs, thigh and buttocks after activities. Electrical neurostimulation based on the "Gate Theory of Pain" is a known to way to reduce pain but current devices to do this are bulky and not well suited to implantation in peripheral tissues. There is also an increased risk associated with surgery

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Boieiro, Inês Mónica 1991. "Estágio no Centro de Medicina de Reabilitação da Região Centro - Rovisco Pais : avaliação do estado nutricional e da capacidade funcional de doentes com diagnóstico clínico de AVC." Master's thesis, 2016. http://hdl.handle.net/10451/33349.

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Relatório de estágio de mestrado, Nutrição Clínica, Universidade de Lisboa, Faculdade de Medicina, 2016<br>Está descrito que a frequência de desnutrição associada à doença afeta cerca de 30 a 60% dos doentes no momento da admissão hospitalar. A desnutrição tem vindo a ser associada a graves consequências, como ao maior risco de infeções e de disfunção de órgãos e a um aumento significativo, não só da morbilidade e mortalidade, como da frequência e dos custos com os cuidados de saúde. A falta de reconhecimento e da monitorização dos aspetos relacionados com o estado nutricional têm sido apontad

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Castel, Aude. "Étude Pharmacologique de la Douleur Neuropathique Centrale à la suite d'une Hémorragie Intrathalamique induite chez le Rat." Thèse, 2013. http://hdl.handle.net/1866/9934.

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La douleur neuropathique centrale post accident vasculaire cérébral est une condition débilitante dont le traitement s’avère souvent délicat et infructueux. Le but de ce projet était de reproduire cette condition chez le rat en injectant par stéréotaxie une solution de collagènase produisant une hémorragie localisée dans le noyau ventropostérolatéral du thalamus. Des tests comportementaux évaluant la coordination motrice, la sensibilité mécanique, au chaud et au froid étaient réalisés régulièrement afin d’établir la présence de douleur neuropathique puis les effets de l’administration de kétam

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Χονδρογιάννη, Χριστίνα. "Μελέτη της έκφρασης των υποδοχέων των νευροτροφινών σε αδενώματα υπόφυσης στον άνθρωπο". Thesis, 2006. http://nemertes.lis.upatras.gr/jspui/handle/10889/1379.

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Οι νευροτροφίνες (ΝΤs), Nerve Growth Factor (NGF), Brain-Derived Neurotrophin Factor (BDNF), NΤ-3, ΝΤ-4, ΝΤ-5 και ΝΤ-6 ανήκουν σε μια οικογένεια πολυπεπτιδικών αυξητικών παραγόντων οι οποίοι απαιτούνται για την ανάπτυξη του νευρικού συστήματος στα σπονδυλωτά. Εμπλέκονται στην επιβίωση, στη διαφοροποίηση, στην ωρίμανση των νευρώνων, στη συναπτική πλαστικότητα, στη μάθηση, στη μνήμη, καθώς επίσης και στην έκφραση και ενεργότητα σημαντικών πρωτεϊνών, όπως ιοντικών καναλιών και νευροδιαβιβαστικών υποδοχέων. Οι λειτουργίες αυτές επιτελούνται μέσω της δέσμευσής τους σε δύο είδη μεμβρανικών υ

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