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Rozprawy doktorskie na temat „Vascular surgery”

Autor: Grafiati

Data publikacji: 4 czerwca 2021

Data aktualizacji: 25 lipca 2025

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1

Cortecchia, Elisa <1983&gt. "New polymeric materials for vascular surgery." Doctoral thesis, Alma Mater Studiorum - Università di Bologna, 2011. http://amsdottorato.unibo.it/3387/1/Cortecchia_Elisa_tesi.pdf.

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The dramatic impact that vascular diseases have on human life quality and expectancy nowadays is the reason why both medical and scientific communities put great effort in discovering new and effective ways to fight vascular pathologies. Among the many different treatments, endovascular surgery is a minimally-invasive technique that makes use of X-ray fluoroscopy to obtain real-time images of the patient during interventions. In this context radiopaque biomaterials, i.e. materials able to absorb X-ray radiation, play a fundamental role as they are employed both to enhance visibility of devices

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Cortecchia, Elisa <1983&gt. "New polymeric materials for vascular surgery." Doctoral thesis, Alma Mater Studiorum - Università di Bologna, 2011. http://amsdottorato.unibo.it/3387/.

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The dramatic impact that vascular diseases have on human life quality and expectancy nowadays is the reason why both medical and scientific communities put great effort in discovering new and effective ways to fight vascular pathologies. Among the many different treatments, endovascular surgery is a minimally-invasive technique that makes use of X-ray fluoroscopy to obtain real-time images of the patient during interventions. In this context radiopaque biomaterials, i.e. materials able to absorb X-ray radiation, play a fundamental role as they are employed both to enhance visibility of devices

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Sörelius, Karl. "Aortic infections : The Nadir of Vascular Surgery." Doctoral thesis, Uppsala universitet, Kärlkirurgi, 2016. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-300954.

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Aortic infections are rare, life-threatening and constitute a major challenge in surgical management. This thesis aims to evaluate short – and long-term outcome of endovascular aortic repair (EVAR) for mycotic aortic aneurysms (MAA) and the subsequent risk of recurrent infections, changes in surgical practice over time for abdominal MAAs in Sweden and outcome for different treatment modalities, as well as the risk of secondary vascular infection after treatment with Open abdomen after aortic surgery. Paper I, a retrospective single centre study of patients with MAA treated with EVAR, demonstra

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Holbrey, Richard Paul. "Virtual suturing for training in vascular surgery." Thesis, University of Leeds, 2004. http://etheses.whiterose.ac.uk/1326/.

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Today's health professionals are facing a crisis in training needs: on one hand, the working hours of junior doctors and experience at the operating table are being reduced; on the other, patients are growing ever more critical and litigious. VR simulators may be able to provide a solution, but whilst hardware costs have fallen in recent years, they are still expensive when compared to conventional methods and few have been adopted. The challenge for researchers has been to create realistic, but affordable, surgical interfaces and to provide convincing assessments of the resulting systems. The

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5

Holt, Peter James Edward. "Volume-Outcome Relationships and Reporting in Vascular Surgery." Thesis, St George's, University of London, 2008. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.517188.

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6

Little, Charlene Knight. "Decreasing Surgical Site Infections in Vascular Surgery Patients." ScholarWorks, 2016. https://scholarworks.waldenu.edu/dissertations/2412.

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Postoperative surgical site infections are common complications in the operating room. Infections prolong hospital stays, heighten costs, and increase morbidity and mortality. The purpose of this evidence-based quality improvement project was to develop policy, program, and practice guidelines to prevent surgical site infections in vascular surgery patients. Rosswurm and Larrabee's change model was used to develop materials using the best evidence for the recommended practice changes. The Plan, Do, Check, Act model was selected to guide quality improvement. The project goal was to decrease the

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7

Mentor, Keno. "Stabilised decellularised vascular grafts in an ovine carotid model." Master's thesis, University of Cape Town, 2018. http://hdl.handle.net/11427/29785.

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Background: There is an urgent clinical need for an alternative vascular graft, especially for smaller artery applications such as in below-knee and coronary artery bypass. Currently available synthetic grafts have unacceptably low patency rates, while autologous saphenous vein grafts are not feasible in one third of patients. Decellularised vascular grafts have been investigated as alternative conduits, but this chemical treatment results in degradation of the extracellular matrix. Chemical stabilization of elastin with penta-galloyl glucose (PGG) combined with collagen stabilisation during c

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8

Wu, Lily. "Metabolic profile and post-operative outcomes in contemporary patients with peripheral arterial disease and critical limb ischaemia." Master's thesis, University of Cape Town, 2018. http://hdl.handle.net/11427/28147.

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Background: Peripheral arterial disease (PAD) is an established occlusive disease of the peripheral arteries and is not uncommon in the elderly. Atherosclerosis accounts for 90% of the pathology. Only 15% of affected individuals become symptomatic. Most symptomatic individuals present with intermittent claudication (IC). Only a small proportion (1%) of affected individuals present with critical limb ischaemia (CLI). Revascularization aimed at limb salvage, and recovery of ambulation and independent living is the ultimate therapeutic option for the advanced form of PAD (CLI). Traditionally, the

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9

Dube, Bhekifa. "The fate of proximally excluded iliac arteries following open repair of abdominal aortic aneurysms." Master's thesis, University of Cape Town, 2016. http://hdl.handle.net/11427/20965.

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Aneurysms occur throughout the length of the aorta, with a large proportion occurring in the infra-renal segment of the abdominal aorta (least 9 to 10 times more common than thoracic aortic aneurysms). Aneurysmal disease of the aorto-iliac segment which commonly occurs as a result of a degenerative process is invariably a progressive entity. Concomitant iliac artery aneurysms have been noted to occur in 15-40% of patients with abdominal aortic aneurysms (AAAs). As a result, following open AAA repair, there is a concern regarding the progressive enlargement of the iliac arteries. The aim of thi

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10

Irsale, Swagat Appasaheb Adanur Sabit. "Textile prosthesis for vascular applications." Auburn, Ala., 2004. http://hdl.handle.net/10415/953.

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11

Pandey, Vikas. "Training and assessment of technical skill in vascular surgery." Thesis, Imperial College London, 2008. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.490779.

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Recent media attention on high-profile cases of flawed surgical practice has led to increasing awareness amongst the public and surgical profession of the need for quality control in surgery. Vascular surgery remains a highly technical and unforgiving specialty. These factors together with recent reductions in trainees' work hours have driven surgical educators to develop new methods ofenhancing surgical training and assessing technical perfonnance. Simulation using synthetic models allows for augmentation of training and assessing surgical technique whilst avoiding ethical concerns with anima

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12

Halle, Martin. "Vascular inflammation implications for microvascular reconstructive surgery after irradiation /." Stockholm, 2010. http://diss.kib.ki.se/2010/978-91-7409-759-7/.

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13

Jibawi, Abdullah. "Developing better methods for monitoring performance in vascular surgery." Thesis, University of Brighton, 2016. https://research.brighton.ac.uk/en/studentTheses/fa0cab94-9804-4949-bb39-fae9b0f158bd.

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Background - Traditional audit methods are limited in their ability to provide short feedback loop to identify underperforming surgical units in time for them to respond appropriately. Moreover, case mix and other confounding factors limit the usefulness of crude mortality figures. More advanced industrial methods such as cumulative sum method (CUSUM) have therefore become of interest to surgeons. Hypothesis – Continuous monitoring of outcome in aortic aneurysm surgery using CUSUM technique (with optimisation using fractional polynomial mathematical models) can be applied, and do provide signi

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14

Duquette, Janine Lee-Anne. "Preoperative Chlorhexidine Skin Preparation for Patients Undergoing Vascular Surgery." ScholarWorks, 2017. https://scholarworks.waldenu.edu/dissertations/4136.

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In response to improving quality patient care, combined with the growing rates of surgical site infections (SSIs) in vascular patients, the need to explore current practice trends with current evidence has been identified. SSIs affect quality patient care and compromise patient safety. Empirical evidence has recommended the use of a chlorhexidine wash preoperatively to reduce SSIs. Despite this recommended practice, vascular patients were not receiving it in their routine plan of care within a hospital organization in southern Ontario. Guided by Lewin's theory of planned change, this project e

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15

Aitken, Emma L. "Optimising vascular access in incident haemodialysis patients." Thesis, University of Glasgow, 2017. http://theses.gla.ac.uk/8075/.

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Arteriovenous fistula (AVF) are widely considered to be the optimal form of vascular access for haemodialysis incurring fewer complications, superior patency, better dialysis quality and a lower mortality than tunnelled central venous catheters (TCVCs). The use of TCVCs is associated with a six-fold increase in the risk of systemic sepsis, long-term morbidity from central vein stenosis and a higher risk of cardiovascular and all-cause mortality compared to AVF. Despite the relative success of strategies such as “Fistula First” and the best practice target in England and Wales (with simultaneou

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16

Cruickshank, James. "Methodological issues and neuropsychological outcomes following vascular and cardiovascular surgery." Thesis, University of Leeds, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.399884.

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17

Dal, Ponte Donny Brian. "Intimal responses associated with synthetic vascular implants." Diss., The University of Arizona, 2001. http://hdl.handle.net/10150/279867.

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The recorded use of medical implants dates to before Christ. Synthetic cardiovascular implants, more specifically, have been widely used since the 1960s. While research and emerging technologies have achieved numerous advances in this latter field, the host body still recognizes many implants as "foreign" and initiates a healing response that can ultimately interfere with the long-term function of the prostheses. Particular to the area of synthetic vascular grafts, biological responses include platelet activation, thrombosis, and smooth muscle cell migration and proliferation. These reactions

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18

Davies, A. H. "Haemodynamic and venous factors in femoro-distal bypass." Thesis, University of Oxford, 1993. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.333173.

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19

Rajagopalan, Sriram. "Platelet activation, biomarkers and troponin 1 release following major vascular surgery." Thesis, Available from the University of Aberdeen Library and Historic Collections Digital Resources, 2009. http://digitool.abdn.ac.uk:80/webclient/DeliveryManager?application=DIGITOOL-3&owner=resourcediscovery&custom_att_2=simple_viewer&pid=26245.

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20

Cao, Ziquan. "VEGF-mediated vascular functions in health and disease." Doctoral thesis, Linköpings universitet, Avdelningen för kardiovaskulär medicin, 2015. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-117356.

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Angiogenesis is essential for physiological processes including embryonic development, tissue regeneration, and reproduction. Under various pathological conditions the same angiogenic process contribute to the onset, development, and progression of many human diseases including cancer, diabetic complications, ocular disease, chronic inflammation and cardiovascular disease. Vascular endothelial growth factor (VEGF) is a key angiogenic factor for physiological and pathological angiogenesis. In addition to its strong angiogenic activity, VEGF also potently induces vascular permeability, often cau

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21

Howd, Alison. "The critically ischaemic lower limb." Thesis, University of Newcastle Upon Tyne, 1989. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.241411.

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22

Da, Silva Natercia. "Ultrasonography Evaluation of Patency of Implanted Infra-Renal Vascular Grafts in the Rat Model." Master's thesis, Faculty of Health Sciences, 2020. http://hdl.handle.net/11427/32616.

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Introduction: Intensive research over the last six decades has resulted in minimal improvement in vascular graft development. Small animal models are the first line of species exposed to vascular graft implantation and invasive monitoring of experimental graft patency may contribute to pain, suffering, higher cost and earlier sacrifice. Non-invasive ultrasonographic evaluation of vascular implants during the conduction of animal studies allows for chronic follow-up with multiple assessments. This study aims to apply and endorse the utilization of ultrasound as a less invasive diagnostic method

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23

White, Samuel Scott. "Visualization of flow phenomena in a vascular graft model." Thesis, Georgia Institute of Technology, 1989. http://hdl.handle.net/1853/16887.

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Kottegoda, Preethi Nirmalie. "Statistical analysis of survival data : an application to perhipheral vascular bypass surgery." Thesis, University of British Columbia, 1985. http://hdl.handle.net/2429/25912.

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A retrospective study was carried out on 535 patients who underwent bypass surgery for peripheral vascular disease. Survival data for 303 patients out of these 535 cases are subjected to quantitative analysis. The main interest is in survival of these patients in order to identify the risk factors. The importance of types of grafting technique in long-term survival is also considered. Statistical methods used to ascertain the important prognostic variables include Cox's proportional hazards model, stepwise regression and all subsets regression in proportional hazards model discussed by Kuk (1

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25

Baker, R. C. "Modulation of peri-operative renal injury in a model of vascular surgery." Thesis, Queen's University Belfast, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.396890.

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26

Rudström, Håkan. "Iatrogenic Vascular Injuries." Doctoral thesis, Uppsala universitet, Kärlkirurgi, 2013. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-194346.

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Iatrogenic vascular injuries (IVIs) and injuries associated with vascular surgery can cause severe morbidity and death. The aims of this thesis were to study those injuries in the Swedish vascular registry (Swedvasc), the Swedish medical injury insurance where insurance claims are registered, the Population and Cause of death registries, and in patient records, in order to explore preventive strategies. Among 87 IVIs during varicose vein surgery 43 were venous, mostly causing bleeding in the groin. Among 44 arterial injuries, only 1/3 were detected intraoperatively. Accidental arterial strippi

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Javed, Sumbal. "Reconfiguration of vascular services to enhance quality of care." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2014. http://hdl.handle.net/10722/206915.

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Hong Kong's aging population has, increased demand for vascular services. Currently, vascular surgery is subsumed under general surgery. The workload on both general surgery and vascular surgery is demanding and hence, not conductive to the development of vascular surgery. The volume of surgery, particularly emergency surgery provided by the Hospital Authority units varies significantly. The collaboration and differentiation of labor at present is not well defined in many centers. This may lead to unnecessary competition and duplication of resources in the long run. This project examined if t

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Bryce, Gavin John. "Preoperative cardiac risk assessment in vascular surgery : risk stratification, novel cardiac biomarkers, and their importance in abdominal aortic aneurysm surgery." Thesis, University of Glasgow, 2011. http://theses.gla.ac.uk/2628/.

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Major vascular surgery is associated with a substantial risk of cardiovascular events and death. This risk is of increased importance in prophylactic elective open Abdominal Aortic Aneurysm (AAA) repair, where a balance of risk of rupture and postoperative outcome is assessed prior to management decisions. Further, the UK Small Aneurysm Trial has shown that prophylactic repair of an AAA has no survival benefit for the first three years due to the major adverse cardiac event (MACE) rate of 5-15%. There is however no ideal method of predicting this risk. Cardiac Troponin I (cTnI) is a contractil

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29

Green, Ian Linley. "Common femoral pulse profile in the assessment of aorto-iliac disease." Thesis, Imperial College London, 1986. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.283588.

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Rattray, Andrew. "Platelet response to haemodynamic shear forces." Thesis, University of Liverpool, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.367819.

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Ghauri, A. Saboor K. "The influence on outcome of a vascular-led community-based service for the care of patients with chronic leg ulcers." Thesis, University of Bristol, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.369790.

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Chen, Sean Jy-Shyang. "Development and validation of vascular image processing techniques for image-guided neurovascular surgery." Thesis, McGill University, 2014. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=123108.

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The effectiveness of image guided neurosurgery (IGNS) depends on the presen-tation of accurate image data to a neurosurgeon for surgical planning and guidance.The blood vessels supplying the brain are of particular importance in IGNS, becausethey densely surround brain lesions and tumours, may themselves be the sites ofpathologies, and need to be carefully considered during surgery.Given the importance of visualizing and identifying vasculature for diagnosis,planning, and guidance, there is a strong need for automated vessel enhancementand registration techniques. Furthermore, tools for the ch

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33

Kleintjes, Wayne George. "The vascular anatomy of the forehead related to forehead flaps and its application in plastic and reconstructive surgery." Thesis, Stellenbosch : University of Stellenbosch, 2007. http://hdl.handle.net/10019.1/1144.

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Byrom, Michael. "Development of a novel bio-engineered vascular bypass conduit." Thesis, The University of Sydney, 2014. http://hdl.handle.net/2123/12128.

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This thesis summarises the deficiencies of current small-diameter synthetic conduits and the approaches to the development of an improved vascular bypass conduit. Evidence for the incorporation of elastin in the design of novel conduits is then presented. We used recombinant human tropoelastin (rhTE) to develop two novel conduits. Firstly we hypothesised that rhTE can be bound to expanded polytetrafluoroethylene (ePTFE) conduits resulting in improved biocompatibility due solely to altered surface composition. rhTE was covalently bound to 6mm-diameter ePTFE and demonstrated uniform and durable

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Grant, Stuart William. "Risk prediction models in cardiovascular surgery." Thesis, University of Manchester, 2014. https://www.research.manchester.ac.uk/portal/en/theses/risk-prediction-models-in-cardiovascular-surgery(1befbc5d-2aa6-4d24-8c32-e635cf55e339).html.

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Objectives: Cardiovascular disease is the leading cause of mortality and morbidity in the developed world. Surgery can improve prognosis and relieve symptoms. Risk prediction models are increasingly being used to inform clinicians and patients about the risks of surgery, to facilitate clinical decision making and for the risk-adjustment of surgical outcome data. The importance of risk prediction models in cardiovascular surgery has been highlighted by the publication of cardiovascular surgery outcome data and the need for risk-adjustment. The overall objective of this thesis is to advance risk

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36

Black, Stephen Alan. "Simulated carotoid endarterectomy is a valid means of training and assessment in vascular surgery." Thesis, Imperial College London, 2009. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.501458.

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Van, der Merwe Wynand Louw. "Renal dysfunction associated with infrarenal cross clamping of the aorta during major vascular surgery." Thesis, Stellenbosch : Stellenbosch University, 2000. http://hdl.handle.net/10019.1/51895.

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Dissertation (MD)--Stellenbosch University, 2000.<br>ENGLISH ABSTRACT: Acute renal failure still is, with the exception of cardiac deaths, the most important pathological process associated with perioperative mortality in patients operated for abdominal aortic aneurysms. The intraoperative change in renal blood flow (RBF) and glomerular function have been investigated in human and animal models, particularly over the past 15 years. Despite large variation in study populations, measurement techniques and study designs in general, a significant body of evidence has developed which suggest

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38

Schmid, Markus. "Vascular adaption of the internal mammary artery graft early and late after bypass surgery /." [S.l.] : [s.n.], 2008. http://www.ub.unibe.ch/content/bibliotheken_sammlungen/sondersammlungen/dissen_bestellformular/index_ger.html.

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Smith, Andrew Hart. "THE ROLE OF CANONICAL TRANSIENT RECEPTOR POTENTIAL CHANNEL SUBTYPE-6 IN PHENOTYPIC MODULATION OF VASCULAR SMOOTH MUSCLE CELLS AND ARTERIAL HEALING AFTER VASCULAR INTERVENTION." Case Western Reserve University School of Graduate Studies / OhioLINK, 2021. http://rave.ohiolink.edu/etdc/view?acc_num=case160710077734737.

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Wong, Corrine Jui Yin. "Three and four dimensional computed tomographic angiography of free and pedicled flaps : investigating the vascular territories." Thesis, Queen Mary, University of London, 2013. http://qmro.qmul.ac.uk/xmlui/handle/123456789/8387.

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In plastic surgery, flap reconstruction has been utilised to repair defects in every part of the body, in an effort to restore form and function to patients. The basis of every flap is its blood supply, therefore this series of studies investigates the vascular territory of named arteries, veins and even perforators, utilizing computer tomography (CT) and TeraRecon software. The latter two is technology which allows appreciation of vascular flow in 3D and 4D (dynamic studies), whereas previous studies of vascularity has only been static and in 2D. Vascular anatomy studies were performed using

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41

Pennel, Timothy. "The performance of cross-linked acellular arterial scaffolds as vascular grafts; pre-clinical testing in direct and isolation loop circulatory models." Master's thesis, University of Cape Town, 2016. http://hdl.handle.net/11427/20342.

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There is a significant need for small diameter vascular grafts to be used in peripheral vascular surgery; however autologous grafts are not always available, synthetic grafts perform poorly and allografts and xenografts degenerate, dilate and calcify after implantation. We hypothesized that chemical stabilization of acellular xenogenic arteries would generate off-the-shelf grafts resistant to thrombosis, dilatation and calcification. To test this hypothesis, we decellularized porcine renal arteries, stabilized elastin with pentagalloyl glucose and collagen with carbodiimide/activated heparin a

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Swartbol, Paul. "Blood-graft interactions with special reference to cellular immune-reactivity in vascular and endovascular surgery /." Lund : Dept. of Surgery, Lund University, 1996. http://books.google.com/books?id=GaRsAAAAMAAJ.

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葛志東 and Zhidong Ge. "Endothelium-dependent hyperpolarization and relaxation of coronary circulationg during cardioplegic arrest of the heart." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2000. http://hub.hku.hk/bib/B31241712.

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Mofidi, Reza. "Data mining and associated analytical tools as decision aids for healthcare practitioners in vascular surgery." Thesis, University of Sunderland, 2018. http://sure.sunderland.ac.uk/9553/.

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Vascular surgery is an increasingly data rich speciality. Planning treatment and assessing outcomes are highly dependent on objective assessment of number of imaging modalities including duplex ultrasound, CT scans and angiograms which are almost exclusively digitally created stored and accessed. Developments such as the national vascular registry mean that treatment outcomes are recorded scrutinised electronically. The widespread availability of data which is collected electronically and stored for future clinical use has created the opportunity to examine the efficacy of investigations and t

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Beach, Jocelyn M. "Survival following fenestrated endovascular aortic repair - implications for decision making." Case Western Reserve University School of Graduate Studies / OhioLINK, 2016. http://rave.ohiolink.edu/etdc/view?acc_num=case1465492151.

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Gillespie, Cynthia Ann. "Evaluating an Educational Initiative for Postsurgical Vascular Patients." ScholarWorks, 2019. https://scholarworks.waldenu.edu/dissertations/6432.

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The educational medium GetWellNetWork (GWNW) in a large magnet teaching facility offered few educational videos specific to vascular patients with a focus on leg elevation after lower extremity bypass surgery. Supplying patient-specific education has the potential for providing cost-effective nursing care to vascular patients and improving hospital reimbursement. Guided by the interactive care model, a storyboard was developed using best-practice evidence for vascular postoperative patients that could lead to the development of a video to address the educational needs of vascular patients upon

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Rubira, Cláudio José [UNESP]. "Colocação de endoprótese vascular versus cirurgia para coarctação de aorta: revisão sistemática." Universidade Estadual Paulista (UNESP), 2012. http://hdl.handle.net/11449/101620.

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Made available in DSpace on 2014-06-11T19:31:32Z (GMT). No. of bitstreams: 0 Previous issue date: 2012-08-03Bitstream added on 2014-06-13T20:22:22Z : No. of bitstreams: 1 rubira_cj_dr_botfm.pdf: 240856 bytes, checksum: 5f30f1a1d2ce6492fd56a190c587cfc5 (MD5)<br>Universidade Estadual Paulista (UNESP)<br>A Coarctação da aorta (CoA) é responsável por 5% a 7% das cardiopatias congênitas, com uma incidência de 0,3 a 0,4 por 1000 nascidos vivos. A cirurgia foi a única forma de terapia para CoA até 1982, quando a angioplastia tornou-se uma alternativa disponível para o seu tratamento. Recoarctação,

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Rubira, Cláudio José. "Colocação de endoprótese vascular versus cirurgia para coarctação de aorta : revisão sistemática." Botucatu, 2012. http://hdl.handle.net/11449/101620.

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Orientador: Paulo Eduardo de Oliveira Carvalho<br>Coorientador: Antônio José Maria Catâneo<br>Banca: Luiz Eduardo Villaça Leão<br>Banca: Marcos Augusto Moraes Silva<br>Banca: Olavo Ribeiro Rodrigues<br>Banca: Rúbio Bombonato<br>Resumo: A Coarctação da aorta (CoA) é responsável por 5% a 7% das cardiopatias congênitas, com uma incidência de 0,3 a 0,4 por 1000 nascidos vivos. A cirurgia foi a única forma de terapia para CoA até 1982, quando a angioplastia tornou-se uma alternativa disponível para o seu tratamento. Recoarctação, aneurisma e dissecção da aorta permaneceram desvantagens de ambos os

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Lewis, M. H. "Peripheral arterial disease from aetiology to surgical management." Thesis, University of South Wales, 2013. https://pure.southwales.ac.uk/en/studentthesis/peripheral-arterial-disease-from-aetiology-to-surgical-management(7defd31a-6995-4fc7-9302-2fced42b5982).html.

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The work presented includes over thirty peer reviewed published manuscripts based on studies undertaken during my surgical career. As Principal Investigator, I led the study conception/design/data acquisition/analysis/interpretation and was involved with writing the final drafts of all manuscripts prior to their formal submission to high impact factor peer-reviewed specialist journals. The thesis is divided into subsections reflecting my development and different interests within surgery. The subsections start with my learning basic research principles, moving onto clinical problem solving in

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Jia, Huidong. "Identifying the optimal stem cell populations for vascular tissue regeneration used in paediatric congenital heart surgery." Thesis, University of Bristol, 2015. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.683556.

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Congenital heart disease (CHO) affects 1 % of live births, and remains the primary cause of death among infants in North America and Europe. In congenital heart defect corrective surgery, the commonly used prosthetic replacement grafts have limited durability and often require repeat operations because of their lack of growth potential. Using the child's autologous stem cells to produce tissue engineered vascular grafts holds promise for the creation of living grafts for surgery. It is therefore essential to identify a readily available autologous stem cell source that is able to produce suffi

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