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1

Gilgoff, Irene S. Breath of life: The role of the ventilator in managing life-threatening illnesses. Scarecrow Press, 2001.

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2

J, Marini John, and Slutsky Arthur S. 1948-, eds. Physiological basis of ventilatory support. Marcel Dekker, 1998.

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3

Azriel, Perel, and Stock M. Christine, eds. Handbook of mechanical ventilatory support. Williams & Wilkins, 1991.

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4

L, Nochomovitz Michael, and Montenegro Hugo D, eds. Ventilatory support in respiratory failure. Futura Pub. Co., 1987.

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5

Christine, Stock M., and Perel Azriel, eds. Handbook of mechanical ventilatory support. 2nd ed. Williams & Wilkins, 1997.

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6

R, Kirby Robert, Banner Michael J, and Downs John B, eds. Clinical applications of ventilatory support. Churchill Livingstone, 1990.

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7

1948-, Ambrosino N., and Goldstein Roger, eds. Ventilatory support for chronic respiratory failure. Informa Healthcare, 2008.

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8

Esquinas, Antonio M., ed. Pulmonary Function Measurement in Noninvasive Ventilatory Support. Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-76197-4.

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9

Corporation, Springhouse, ed. Respiratory support. Springhouse Corp., 1991.

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10

Hasan, Rashed A. A pocket guide to mechanical ventilation & other measures of respiratory support. 3rd ed. Booksurge, 2005.

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11

Christine, Mikelsons, ed. Non-invasive respiratory support techniques: Oxygen therapy, non-invasive ventilation, and CPAP. Wiley-Blackwell, 2008.

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12

J, Savoie Martin, and Construction Engineering Research Laboratories (U.S.), eds. Central Heating Plant Modernization Study for the Defense Personnel Support Center. U.S. Army Corps of Engineers, Construction Engineering Research Laboratories, 1994.

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13

Esquinas, Antonio M., and Nicola Vargas, eds. Ventilatory Support and Oxygen Therapy in Elder, Palliative and End-of-Life Care Patients. Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-26664-6.

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14

Oczenski, Wolfgang. Breathing and mechanical support: Physiology of respiration and mechanical methods of artificial ventilation. 2nd ed. Blackwell Science, 1997.

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15

Sames, Gary P. Coal mine air tempering: Effectiveness, design, and roof support. U.S. Dept. of the Interior, Bureau of Mines, 1985.

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16

Joachimsson, Per-Olof. Prevention and treatment of intraoperative hypothermia: Effects on postoperative recovery and the need for mechanical ventilatory support. Uppsala University, 1987.

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17

J, Huang Y., Lawrence Berkeley Laboratory. Applied Science Division., and United States. Dept. of Energy., eds. Methodology and assumptions for evaluating heating and cooling energy requirements in new single-family residential buildings: Technical support document for the Pear microcomputer program. Lawrence Berkeley Laboratory, 1987.

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18

International Conference on Environmental Systems (21st : 1991 : San Francisco, Calif.), ed. Space station ECLSS and thermal control. Society of Automotive Engineers, 1991.

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19

Oliver, Charles M., and S. Ramani Moonesinghe. Setting rate, volume, and time in ventilatory support. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199600830.003.0093.

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Ventilator rate, volume, and time parameters are interrelated directly, mechanically, and physiologically, and interactions between intrinsic pulmonary physio-mechanics, pathology and the effects of mechanical ventilation complex. The physiological consequences of mechanical ventilation and risks of ventilator-induced trauma may be exacerbated by lung pathology. Programming of ventilator parameters should be considered within the context of an individualized ventilatory strategy to achieve adequate gas exchange, while minimizing attendant risks of mechanical ventilation. Recommended strategies
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20

Aguirre-Bermeo, Hérnan, and Jordi Mancebo. Pressure support ventilation. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199600830.003.0097.

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Pressure support ventilation (PSV) is one of the most common ventilatory modalities used in intensive care units. PSV is an assisted, pressure-limited, and flow-cycled ventilatory mode. The ventilator provides assistance when the patient makes a breathing effort, and when inspiratory flow reaches a certain threshold level, cycling to exhalation occurs. PSV unloads respiratory muscle effort, while allowing the patient to retain control over the respiratory rate and tidal volume. Withdrawal from mechanical ventilation should be performed with a gradual reduction of levels of support until extuba
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21

Nava, Stefano, and Luca Fasano. Ventilator Liberation Strategies. Oxford University Press, 2014. http://dx.doi.org/10.1093/med/9780199653461.003.0039.

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The weaning process should ideally begin as soon as the patient is intubated and continue through the treatment of the cause inducing acute respiratory failure. Weaning includes the assessment of readiness to extubate, extubation, and post-extubation monitoring; it also includes consideration of non-invasive ventilation which has been shown to reduce the duration of invasive mechanical ventilation in selected patients. Weaning accounts for approximately 40% of the total time spent on mechanical ventilation and should be achieved rapidly, since prolonged mechanical ventilation is associated wit
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22

Kreit, John W. Ventilator Modes and Breath Types. Edited by John W. Kreit. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780190670085.003.0005.

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Ventilator Modes and Breath Types describes, compares, and contrasts the different modes and breath types that are available on intensive care unit ventilators. The chapter first covers the various ventilator modes: continuous mandatory ventilation, synchronized intermittent mandatory ventilation, spontaneous ventilation, and bi-level ventilation. Then it turns to a discussion of the various mechanical breath types: volume control, pressure control, adaptive pressure control, pressure support, and finally, adaptive pressure support. It also provides practical advice about how and when to use e
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23

Lucangelo, Umberto, and Massimo Ferluga. Pulmonary mechanical dysfunction in the critically ill. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199600830.003.0084.

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In intensive care units practitioners are confronted every day with mechanically-ventilated patients and should be able to sort out from all the data available from modern ventilators to tailored patient ventilatory strategy. Real-time visualization of pressure, flow and tidal volume provide valuable information on the respiratory system, to optimize ventilatory support and avoiding complications associated with mechanical ventilation. Early determination of patient–ventilator asynchrony, air-trapping, and variation in respiratory parameters is important during mechanical ventilation. A correc
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24

Ventilator Induced Lung Injury in Non-Invasive Ventilatory Support: Pathophysiology, Treatment and Prevention. Nova Science Publishers, Incorporated, 2023.

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25

Ventilator Induced Lung Injury in Non-Invasive Ventilatory Support: Pathophysiology, Treatment and Prevention. Nova Science Publishers, Incorporated, 2023.

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26

Waldmann, Carl, Neil Soni, and Andrew Rhodes. Respiratory therapy techniques. Oxford University Press, 2011. http://dx.doi.org/10.1093/med/9780199229581.003.0001.

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Oxygen therapy 2Ventilatory support: indications 6IPPV—description of ventilators 8IPPV—modes of ventilation 10IPPV—adjusting the ventilator 12IPPV—barotrauma 14IPPV—weaning techniques 16High-frequency ventilation 18Positive end-respiratory pressure 22Continuous positive airway pressure ventilation (CPAP) 24Recruitment manoeuvres 26Prone position ventilation 28...
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27

Martin-Loeches, Ignacio, and Antonio Artigas. Respiratory support with positive end-expiratory pressure. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199600830.003.0094.

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Positive-end-expiratory pressure (PEEP) is the pressure present in the airway (alveolar pressure) above atmospheric pressure that exists at the end of expiration. The term PEEP is defined in two particular settings. Extrinsic PEEP (applied by ventilator) and intrinsic PEEP (PEEP caused by non-complete exhalation causing progressive air trapping). Applied (extrinsic) PEEP—is usually one of the first ventilator settings chosen when mechanical ventilation (MV) is initiated. Applying PEEP increases alveolar pressure and volume. The increased lung volume increases the surface area by reopening and
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28

Lei, Yuan. Ventilator Control Parameters. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780198784975.003.0009.

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‘Ventilator Control Parameters’ looks at the individual ventilator settings, which are largely used to quantitatively define the properties of mechanical breaths. Following on from the previous discussion of essential variables, this chapter describes their implementation in the form of controls. This chapter begins by discussing the confusing and non-standardized terminology used for control parameters, providing a list of controls used on major ventilators. Common controls include rate, pressure and flow triggers, inspiratory time, I:E ratio, peak flow, flow cycle, tidal volume, pressure con
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29

Dalton, Heidi J., Mark Davidson, and Peter P. Roeleveld. Extracorporeal Life Support. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780199918027.003.0002.

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Extracorporeal membrane oxygenation (ECMO) can provide support as a bridge to recovery or a bridge to more definitive therapy for patients with severe respiratory or cardiorespiratory disease. In this chapter, the criteria for ECMO are discussed and a practical decision tree for mode of ECMO (venovenous or venoarterial) is presented. A stepwise approach to initiation and management of ECMO for the patient is described, including flow rate goals, ventilator management, anticoagulation, blood product replacement, identification of recovery, weaning procedures, and specific issues relating to the
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30

Beduneau, Gaëtan, Jean-Christophe M. Richard, and Laurent Brochard. Prolonged Respiratory Insufficiency and Ventilator Dependence in the ICU. Oxford University Press, 2014. http://dx.doi.org/10.1093/med/9780199653461.003.0014.

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The process of separation or weaning from mechanical ventilation can be arbitrarily separated into three categories: (1) simple weaning when patients are separated from the ventilator after the first attempt of unsupported spontaneous breathing. This usually represents slightly more than half of the patients; (2) difficult weaning when up to three attempts or 1 week is necessary to successfully separate the patient from the ventilator; (3) prolonged weaning for the remaining patients. This last group represents between 6 and 20% of the ICU population arriving at the stage of weaning and carrie
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31

Lei, Yuan. Mechanical Ventilation Modes. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780198784975.003.0008.

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‘Mechanical Ventilation Modes’ seeks to shed light on this hotly debated topic, one that is complicated by ventilator manufacturers’ non-standardized terminology. The chapter looks at conventional modes, adaptive modes, and biphasic modes, which it classifies based on the mechanical breath types in each mode. It includes a comparison chart of the terminology used for common modes on popular IPPV ventilators. Using their signature waveforms, the author describes the assist/control, SIMV, and pressure support ventilation or PSV modes. It defines the modes by their application of spontaneous brea
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32

Masip, Josep, Kenneth Planas, and Arantxa Mas. Non-invasive ventilation. Oxford University Press, 2015. http://dx.doi.org/10.1093/med/9780199687039.003.0025.

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During the last 25 years, the use of non-invasive ventilation has grown substantially. Non-invasive ventilation refers to the delivery of positive pressure to the lungs without endotracheal intubation and plays a significant role in the treatment of patients with acute respiratory failure and in the domiciliary management of some chronic respiratory and sleep disorders. In the intensive and acute care setting, the primary aim of non-invasive ventilation is to avoid intubation, and it is mainly used in patients with chronic obstructive pulmonary disease exacerbations, acute cardiogenic pulmonar
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33

Masip, Josep, Kenneth Planas, and Arantxa Mas. Non-invasive ventilation. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199687039.003.0025_update_001.

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During the last 25 years, the use of non-invasive ventilation has grown substantially. Non-invasive ventilation refers to the delivery of positive pressure to the lungs without endotracheal intubation and plays a significant role in the treatment of patients with acute respiratory failure and in the domiciliary management of some chronic respiratory and sleep disorders. In the intensive and acute care setting, the primary aim of non-invasive ventilation is to avoid intubation, and it is mainly used in patients with chronic obstructive pulmonary disease exacerbations, acute cardiogenic pulmonar
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34

Masip, Josep, Kenneth Planas, and Arantxa Mas. Non-invasive ventilation. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780199687039.003.0025_update_002.

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During the last 25 years, the use of non-invasive ventilation has grown substantially. Non-invasive ventilation refers to the delivery of positive pressure to the lungs without endotracheal intubation and plays a significant role in the treatment of patients with acute respiratory failure and in the domiciliary management of some chronic respiratory and sleep disorders. In the intensive and acute care setting, the primary aim of non-invasive ventilation is to avoid intubation, and it is mainly used in patients with chronic obstructive pulmonary disease exacerbations, acute cardiogenic pulmonar
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35

Lee, Jan Hau, and Ira M. Cheifetz. Respiratory Failure and Mechanical Ventilation. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780199918027.003.0006.

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This chapter on respiratory failure and mechanical ventilation provides essential information about how to support children with severe respiratory disorders. The authors discuss multiple modes of respiratory support, including high-flow nasal cannula oxygen, noninvasive ventilation with continuous positive airway pressure and bilevel positive airway pressure, as well as conventional, high-frequency, and alternative modes of invasive ventilation. The section on invasive mechanical ventilation includes key information regarding gas exchange goals, modes of ventilation, patient–ventilator intera
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36

Bellani, Giacomo, and Antonio Pesenti. Treating respiratory failure with extracorporeal support in the ICU. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199600830.003.0105.

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During extracorporeal support or extracorporeal membrane oxygenation (ECMO) blood is diverted from the patient to an artificial lung for gas exchange, then returned into the patient’s circulation once arterialized. While a low-blood-flow bypass can remove comparatively high amounts of CO2, oxygenation is limited by venous haemoglobin saturation and requires high flows. Several technical improvements led to a profound change in the safety and applicability of ECMO in recent years, even permitting the transfer of patients undergoing ECMO. ECMO has been proposed as salvage therapy for the most se
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37

Muders, Thomas, and Christian Putensen. Pressure-controlled mechanical ventilation. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199600830.003.0096.

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Beside reduction in tidal volume limiting peak airway pressure minimizes the risk for ventilator-associated-lung-injury in patients with acute respiratory distress syndrome. Pressure-controlled, time-cycled ventilation (PCV) enables the physician to keep airway pressures under strict limits by presetting inspiratory and expiratory pressures, and cycle times. PCV results in a square-waved airway pressure and a decelerating inspiratory gas flow holding the alveoli inflated for the preset time. Preset pressures and cycle times, and respiratory system mechanics affect alveolar and intrinsic positi
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38

S, Gilgoff Irene. Breath of Life: The Role of the Ventilator in Managing Life-Threatening Illnesses. The Scarecrow Press, Inc., 2002.

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39

Masip, Josep, Kenneth Planas, and Arantxa Mas. Non-invasive ventilation. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780199687039.003.0025_update_003.

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During the last 25 years, the use of non-invasive ventilation has grown substantially. Non-invasive ventilation refers to the delivery of positive pressure to the lungs without endotracheal intubation and plays a significant role in the treatment of patients with acute respiratory failure and in the domiciliary management of some chronic respiratory and sleep disorders. In the intensive and acute care setting, the primary aim of non-invasive ventilation is to avoid intubation, and it is mainly used in patients with chronic obstructive pulmonary disease exacerbations, acute cardiogenic pulmonar
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40

Russo, Sebastian G., and Michael Quintel. Standard intubation in the ICU. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199600830.003.0080.

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Due to secretions, blood, or oedema in the patients’ airways, compromised pulmonary and haemodynamic, as well as limited access to the patients’ head the standard intubation in the ICU is an overall challenging procedure. Planning, preparation, and straight forwarded strategies are therefore mandatory. As a basic measure, sufficient pre-oxygenation should always be performed. Repetitive intubation attempts significantly worsen patients’ outcomes and need to be avoided. As adequate anaesthesia, including full neuromuscular blockade, can facilitate orotracheal intubation, this should be part of
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41

Dhand, Rajiv, and Michael McCormack. Bronchodilators in critical illness. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199600830.003.0033.

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Inhaled beta-agonists and anticholinergic agents, as well as systemically administered methylxanthines, are frequently employed to achieve bronchodilation in critically-ill patients. Inhaled agents are given by pressurized metered dose inhaler (pMDI), nebulizer, or dry powder inhaler. In ventilator-supported patients, aerosolized agents are generally only administered by pMDI or nebulizer. The ventilator circuit, artificial airway, and circuit humidity complicate the delivery of aerosolized agents, and there is a wide variability in drug delivery efficiency with various bench models of mechani
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42

Marini, John. Physiological Basis of Ventilatory Support. Taylor & Francis Group, 1998.

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43

Fox, Grenville, Nicholas Hoque, and Timothy Watts. Respiratory support. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780198703952.003.0008.

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This chapter includes sections on various modes of both invasive (i.e. via an endotracheal tube) and non-invasive respiratory support in neonates, including conventional ventilation, volume-targeted ventilation, high-frequency oscillatory ventilation (HFOV), extracorporeal membrane oxygenation (ECMO), nasal continuous positive airways pressure (nCPAP), nasal intermittent positive pressure ventilation (nIPPV), and high and low-flow nasal cannula oxygen. There is also a brief section on the care of babies with a tracheostomy as well as management of babies requiring home oxygen. Reference is mad
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44

Ambrosino, Nicolino, and Roger S. Goldstein. Ventilatory Support for Chronic Respiratory Failure. Taylor & Francis Group, 2008.

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45

Ambrosino, Nicolino, and Roger S. Goldstein, eds. Ventilatory Support for Chronic Respiratory Failure. CRC Press, 2008. http://dx.doi.org/10.3109/9781420020229.

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46

Ambrosino, Nicolino, and Roger S. Goldstein. Ventilatory Support for Chronic Respiratory Failure. Taylor & Francis Group, 2008.

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47

Ambrosino, Nicolino, and Roger S. Goldstein. Ventilatory Support for Chronic Respiratory Failure. Taylor & Francis Group, 2019.

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48

Glasper, Edward Alan, Gillian McEwing, and Jim Richardson, eds. High-dependency care. Oxford University Press, 2010. http://dx.doi.org/10.1093/med/9780198569572.003.0025.

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Assessing airway safety 788Assisting with tracheal tube intubation 790Insertion of a nasopharyngeal airway 792Assessing respiratory effectiveness 794Assessing perfusion 796Haemodynamic monitoring 798Methods of non-invasive respiratory support 800Invasive methods of respiratory support 802Care of the ventilated child 804Complications of intubation and ventilation ...
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49

Oliver, David. End of life: Wishes, values and symptoms, and their impact on quality of life and well-being. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780198757726.003.0013.

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The holistic assessment of the patient with ALS and their family will help to maximize the care as the disease progresses and the end of life approaches. This includes consideration of advance care planning, so that the person’s wishes are known if they lose capacity or communication late in the disease course. Discussion of ventilatory support, either by non-invasive ventilation or tracheostomy ventilation, is particularly important so that decisions are not made in a crisis situation. Although ventilatory support may improve quality of life (QoL) and length of survival, there may be increase
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50

Clochesy, John Michael. FACTORS INFLUENCING WEANING ADULTS FROM LONG-TERM POSITIVE PRESSURE MECHANICAL VENTILATORY SUPPORT (LEFT VENTRICULAR, VENTILATORY SUPPORT). 1993.

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