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1

Abisror, N., Y. Nguyen, L. Marozio, et al. "AB0457 OBSTETRICAL OUTCOME AND TREATMENTS DURING PREGNANCY IN SERONEGATIVE PRIMARY APS: DATA FROM EUROPEAN RETROSPECTIVE STUDY." Annals of the Rheumatic Diseases 79, Suppl 1 (2020): 1527.1–1527. http://dx.doi.org/10.1136/annrheumdis-2020-eular.3537.

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Background:Objectives:To compare clinical characteristics, pregnancies, and treatments during pregnancies of seronegative and seropositive APS, and analyse factors associated with adverse obstetrical outcomes.Methods:Inclusion criteria were: (1) thrombotic arterial and/or venous; and /or obstetrical primary clinical APS (Sydney criteria); (2) absence of conventional antiphospholipid antibodies; (3) presence of at least one non-conventional APL among IgA ACL, IgA antiB2GPI, anti-vimentin G/M, anti-annexin V G/M, anti-PE G/M, anti-PS/PT G/M antibodies. The exclusion criteria were: (1) seropositi
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2

Jiang, J., A. Shaker, and H. Zhang. "PREFACE: TECHNICAL COMMISSION III." ISPRS Annals of the Photogrammetry, Remote Sensing and Spatial Information Sciences V-3-2021 (June 17, 2021): 7. http://dx.doi.org/10.5194/isprs-annals-v-3-2021-7-2021.

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Abstract. The work of ISPRS Technical Commission III is devoted to remote sensing. For the XXIVth ISPRS CONGRESS – 2021 Edition (Digital), Technical Commission III received total 201 submissions, including 72 full papers and 138 abstracts. Among these submissions 38 are accepted as peer-reviewed contributions for publication in the ISPRS Annals, 118 were accepted for publication in the ISPRS Archives.These papers are dedicated mostly to topics of the 10 TC III working groups and 4 inter-commission working groups as follows – WG III/1: Thematic Information Extraction; WG III/2: Microwave Remote
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Jiang, J., A. Shaker, and H. Zhang. "PREFACE: TECHNICAL COMMISSION III." International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences XLIII-B3-2021 (June 28, 2021): 7. http://dx.doi.org/10.5194/isprs-archives-xliii-b3-2021-7-2021.

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Abstract. The work of ISPRS Technical Commission III is devoted to remote sensing. For the XXIVth ISPRS CONGRESS – 2021 Edition (Digital), Technical Commission III received total 201 submissions, including 72 full papers and 138 abstracts. Among these submissions 38 are accepted as peer-reviewed contributions for publication in the ISPRS Annals, 118 were accepted for publication in the ISPRS Archives.These papers are dedicated mostly to topics of the 10 TC III working groups and 4 inter-commission working groups as follows – WG III/1: Thematic Information Extraction; WG III/2: Microwave Remote
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4

Peineau, Stéphane, Fabien Guimiot, Zsolt Csaba, et al. "Somatostatin Receptors Type 2 and 5 Expression and Localization During Human Pituitary Development." Endocrinology 155, no. 1 (2014): 33–39. http://dx.doi.org/10.1210/en.2013-1683.

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Somatostatin (SRIF), by acting mainly through sst2 and sst5 receptors, is a potent inhibitor of hormonal secretion by the human anterior pituitary gland. However, the pattern of protein expression of these SRIF receptors remains unknown during pituitary development. To get further insights into the physiological role of SRIF receptors in human development and pituitary function, the present study examined the developmental expression of the sst2 and sst5 receptors in the individual cell types of the anterior human pituitary. Thirteen fetal human pituitaries were investigated between 13 to 38 w
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5

Buzatu, Mihaela Alina, Gicuța Sbîrciog, Stelica Cristea, and Costache Marcel. "ACTIVE INGREDIENTS COMBINATIONS FOR PATHOGENS AND PESTS CONTROL ON EGGPLANT CROPS IN THE FIELD." Romanian journal of Horticulture 1, no. 1 (2020): 37–42. http://dx.doi.org/10.51258/rjh.2020.05.

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The present study aims to identify combinations of active substances for the complex control of pathogens and pests on eggplant crops in the field. The experiments were conducted between 2016 - 2017, in field conditions, using the variety of eggplant Luiza and the following experimental variants: V 1 - Acrobat MZ 69 WG 0.2% + Mospilan 20 SG 0.04%; V 2 - Acrobat MZ 69 WG 0.2% + Vertimec 1.8 EC 0.1%; V 3 - Acrobat MZ 69 WG 0.2% + Laser 240 SC 0.05%; V 4 - Melody Compact 49 WG 0.2% + Mospilan 20 SG 0.04%; V 5 - Melody Compact 49 WG 0.2% + Vertimec 1.8 EC 0.1%; V 6 - Melody Compact 49 WG 0.2% + La
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Putman, Charles T., Karen J. B. Martins, Maria E. Gallo та ін. "α-Catalytic subunits of 5′AMP-activated protein kinase display fiber-specific expression and are upregulated by chronic low-frequency stimulation in rat muscle". American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 293, № 3 (2007): R1325—R1334. http://dx.doi.org/10.1152/ajpregu.00609.2006.

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5′-AMP-activated protein kinase (AMPK) signaling initiates adaptive changes in skeletal muscle fibers that restore homeostatic energy balance. The purpose of this investigation was to examine, in rats, the fiber-type protein expression patterns of the α-catalytic subunit isoforms in various skeletal muscles, and changes in their respective contents within the tibialis anterior (TA) after chronic low-frequency electrical stimulation (CLFS; 10 Hz, 10 h daily), applied for 4 ± 1.2 or 25 ± 4.8 days. Immunocytochemical staining of soleus (SOL) and medial gastrocnemius (MG) showed that 86 ± 4.1 to 9
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BOURGEOIS, P. Y., M. OXBORROW, M. E. TOBAR, N. BAZIN, Y. KERSALÉ, and V. GIORDANO. "MASER OSCILLATION FROM ELECTRONIC SPIN RESONANCE IN A CRYOGENIC SAPPHIRE FREQUENCY STANDARD." International Journal of Modern Physics B 20, no. 11n13 (2006): 1606–12. http://dx.doi.org/10.1142/s0217979206034157.

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We report the first observation of an Fe3+ maser oscillation at zero magnetic field inside a whispering gallery (WG) sapphire resonator. The described maser is new in that it operates at zero-field and with low ion concentration. At zero-field, the Fe3+ ion shows a 3-level structure related to the electron spin resonance (ESR). By applying a 31 GHz pump (|1/2〉 → |5/2〉), the ion operates as a maser at 12 GHz (|5/2〉 → |3/2〉). The maser effect is made possible by the high Q-factor (several 108) of the cryogenic whispering gallery resonator. Additionnaly, the sharp cavity resonance provides short
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8

Delp, Michael D. "Myogenic and vasoconstrictor responsiveness of skeletal muscle arterioles is diminished by hindlimb unloading." Journal of Applied Physiology 86, no. 4 (1999): 1178–84. http://dx.doi.org/10.1152/jappl.1999.86.4.1178.

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The purpose of the present study was to determine whether hindlimb unloading of rats alters vasoconstrictor and myogenic responsiveness of skeletal muscle arterioles. After either 2 wk of hindlimb unloading (HU) or cage control (C), second-order arterioles were isolated from the white portion of gastrocnemius (WG; C: n = 9, HU: n = 10) or soleus (Sol; C: n = 9, HU: n = 10) muscles and cannulated with two micropipettes connected to reservoir systems for in vitro study. Intraluminal pressure was set at 60 cmH2O. The arterioles were exposed to step changes in intraluminal pressure ranging from 20
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9

Sukarman, Sukarman, Siti Murniasih, Rendy Gynanjar, et al. "SAND CRAB (Emerita sp.) MEAL AS A NOVEL FEED INGREDIENT FOR KOI CARP (Cyprinus carpio)." Indonesian Aquaculture Journal 18, no. 2 (2023): 155. http://dx.doi.org/10.15578/iaj.18.2.2023.155-167.

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Sand crab (Emerita sp.) is a marine biodiversity, but it has not been used as a fish feed ingredient. This study aimed to evaluate the nutritional value of sand crabs and to understand its effect when used as feed ingredient on the performance of Koi carp. The study was conducted in two steps, which is evaluation of the nutritional value of sand crab and its effect on fish performance. The proximate composition, amino acids, and fatty acids were measured using AOAC methods, and then the carotenoid content was determined by spectrophotometry. In the second step, the sand crab was added to fish
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10

Amrein, Philip C., Xin Kai, Yasuyuki Iuchi, et al. "Inhibition of Phosphorylation of ERK in CLL Cells Pre-Treatment Correlates Best with Response to Dasatinib, Fludarabine, and Rituximab for Patients with Relapsed CLL." Blood 124, no. 21 (2014): 3636. http://dx.doi.org/10.1182/blood.v124.21.3636.3636.

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Abstract Survival, proliferation, and resistance to chemotherapy in CLL cells have been consistently shown to be associated with the activity of the B-cell receptor (BCR) and the associated downstream pathways activated by it. Key molecules in this pathway are Lyn and Syk (Spleen tyrosine kinase), as well as PI3K, Btk (Bruton’s tyrosine kinase), and ERK. Dasatinib, given at standard doses, allows for serum levels well above 11 nM, the IC50 for the direct suppression of Lyn kinase and Btk. We have previously shown that dasatinib used as a single agent in patients with relapsed CLL results in ly
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11

Wierda, William G., Susan O'Brien, Alessandra Ferrajoli, et al. "Pretreatment Patient Characteristics Associated with Achieving Bone Marrow Minimal Residual Disease-Free Status with Frontline Fludarabine, Cyclosphosphamide, Rituximab (FCR) Chemoimmunotherapy for CLL,." Blood 118, no. 21 (2011): 3902. http://dx.doi.org/10.1182/blood.v118.21.3902.3902.

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Abstract Abstract 3902 Chemoimmunotherapy (CIT) is highly effective treatment and standard of care for patients (pts) with CLL. Response to treatment by NCI-WG/IWCLL criteria correlates with outcome; pts who achieve complete remission (CR) have superior progression-free and overall survival compared to pts who achieve partial remission (PR); and pts who fail therapy have the poorest outcome. Emerging data indicate improved outcomes for pts who achieve minimal residual disease (MRD)-free status in blood or bone marrow (BM) by end of treatment. We are conducting a clinical trial to prospectively
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12

Hoque, MZ, AM Akanda, MIH Miah, MKA Bhuiyan, MG Miah, and F. Begum. "In vitro screening of fungicides and tannins against fungal pathogens of jujube fruits." Progressive Agriculture 27, no. 2 (2016): 154–61. http://dx.doi.org/10.3329/pa.v27i2.29325.

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The aim of this study to identify the effective fungicides for controlling major leaf and fruit diseases of Jujube caused by different fungal pathogens. An in vitro experiment was undertaken to screen ten fungicides and two Tannins against six important fungal pathogens of Jujube fruits which were Alternaria alternata, Colletotrichum gloeosporioides, Curvularia lunata, Lasiodiplodia theobromae, Fusarium semitectum and Pestalotiopsis palmarum. Fungicides were Conza 5 EC (Hexaconazole), Folicur 250 EC (Tebuconazole) and Potent 250 EC (Propiconazole), Bavistin DF (Carbendazim), Kasumin 2% liquid
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13

Diana, Thiago Ferreira, Luiz Fernando Teixeira Albino, Horácio Santiago Rostagno та ін. "Xylanase and β-glucanase in maize- and soybean meal-based diets for broilers". Semina: Ciências Agrárias 41, № 6supl2 (2020): 3259–74. http://dx.doi.org/10.5433/1679-0359.2020v41n6supl2p3259.

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The objective of this study was to evaluate the effect of adding different xylanase and ?-glucanase enzyme blends to maize- and soybean meal-based diets on performance and energy metabolizability in broilers. Two experiments were carried out with broilers of the COBB 500 strain. In the first experiment, 1960 chicks were assigned to a completely randomized design with a 2 × 3 + 1 factorial arrangement, totaling seven treatments, namely, T1- Positive control (PC); T2 - Negative control 1 (NC1; PC minus 200 kcal kg-1 ME); T3 - NC1 + Blend A; T4 - NC1 + Blend B; T5 - Negative control 2 (NC2; PC mi
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14

Jansson, R. K., S. H. Lecrone, and R. Lance. "Management of Lepidopterous Pests on Cabbage, 1991." Insecticide and Acaricide Tests 18, no. 1 (1993): 104–5. http://dx.doi.org/10.1093/iat/18.1.104.

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Abstract ‘Rio Verde’ cabbage seeds were incorporated into a germination mix (Pro-Mix) and direct seeded into a Rockdale soil at the University of Florida’s Tropical Research and Education Center on 13 Feb 1991. The soil was fumigated with Terr-O-Gas (75% methyl bromide, 25% chloropicrin; 246 kg/ha) and covered with white on black plastic mulch on 6 Feb. Plants were spaced 0.3 m apart within rows and 0.76 m apart between rows on 1.8 m-center beds. Fertilizer (1680 kg/ha of granular 6:12:12) was applied and incorporated into the soil on 5 Feb. Goal 2 EC was applied (0.56 kg (AI)/ha) between the
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15

Scarpellini, J. R. "SELETIVIDADE FISIOLÓGICA DE AFICIDAS SOBRE JOANINHA CYCLONEDA SANGUINEA (LINNAEUS, 1763) (COLEOPTERA, COCCINELLIDAE) EM ALGODOEIRO." Arquivos do Instituto Biológico 75, no. 2 (2008): 195–202. http://dx.doi.org/10.1590/1808-1657v75p1952008.

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RESUMO Com o objetivo de verificar o efeito do tiametoxam, diafentiuron e pimetrozina sobre a joaninha Cycloneda sanguinea e sua presa Aphis gossypii em algodoeiro cultivar Deltaopal foi realizado este estudo, em Ribeirão Preto, SP. Foram testados os seguintes tratamentos (g i.a./ha): Tiametoxan 250 WG (50,0); Pimetrozina 500 PM (100); Diafentiuron 500 SC (250); Tiametoxan 250 WG mais Pimetrozina 500 PM (42,5 + 75); Carbosulfano (160); Imidacloprido 200 SC (50) e testemunha. Foram amostradas 25 plantas inteiras por parcela, avaliando-se o número de pulgões. O estudo de seletividade constou de
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16

Skinner Taylor, C. M., G. A. López-Uriarte, L. Pérez Barbosa, et al. "AB0002 CONGENITAL DEFECTS IN A COHORT OF PREGNANT WOMEN FROM A CLINIC OF RHEUMATIC DISEASES AND PREGNANCY." Annals of the Rheumatic Diseases 79, Suppl 1 (2020): 1305.2–1305. http://dx.doi.org/10.1136/annrheumdis-2020-eular.4537.

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Background:Some studies have suggested an increased risk of adverse health outcomes for the child of patients with Rheumatic Diseases (RD), including neurodevelopmental disorders, congenital heart defects, hematological malignancies and autoimmune diseases. It is well known that 2 to 3% of live births have a congenital defect. About 7 % of all newborn deaths are due to birth defects.Objectives:Describe Genetical Evaluation in a cohort of pregnant patients with RDMethods:We included 22 women from February to December 2019 from a Clinic of Pregnancy and Rheumatic Diseases in Hospital Universitar
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17

Lee, Yueh-Sheng, Kuo-Lung Ku, Chi-Shih Chu, and Kuo-Lung Chen. "The Optimal Supplementation of Fermented Product Produced by Bacillus subtilis Strain LYS1 with High Surfactin Yield for Improving Growth Performance, Intestinal Villi Morphology, and Tibial Bone Strength in Broilers." Animals 14, no. 14 (2024): 2079. http://dx.doi.org/10.3390/ani14142079.

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This study aimed to investigate the physiochemical characterizations of the fermented product (FP) produced by the high-yield surfactin strain Bacillus subtilis LYS1 (LYS1), as well as its effects on growth performance, carcass traits, intestinal morphology, tibial bone characteristics, and clinical blood biochemistry in broilers. Accordingly, the optimal supplementation of FP for improving growth performance, intestinal villi development, and tibial bone strength in broilers was elucidated using a broken-line quadratic (BLQ) ascending model. Three hundred and sixty 0-day-old Ross 308 broiler
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Ingle, Y. V., K. A. Lengare, P. R. Damre, and K. T. Lahariya. "Chemical Fungicides and Antagonists as Potential Treatments for Ganoderma lucidum-Associated Basal Stem Rot in Mandarin Trees." Journal of Advances in Biology & Biotechnology 27, no. 7 (2024): 988–96. http://dx.doi.org/10.9734/jabb/2024/v27i71059.

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Ganoderma lucidum causes basal stem rot disease in mandarin trees, resulting in a variety of symptoms including dieback, foliage discoloration, an unhealthy appearance and eventual tree declines or death. Prior to field application, it is imperative to assess the efficacy of newer molecules and possible potential antagonists through In vitro testing. In this study, ten chemical fungicides and four antagonists were evaluated for their effectiveness against G. lucidum using the poison food method and dual culture technique, respectively. Among the chemical fungicides tested, Copper oxychloride 5
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N T, DILEEP KUMAR, and BIRADAR A P. "Bio-efficacy of bio-rationals against citrus leaf miner (Phyllocnistis citrella) in acid lime (Citrus aurantiifolia)." Indian Journal of Agricultural Sciences 94, no. 5 (2024): 545–51. http://dx.doi.org/10.56093/ijas.v94i5.132715.

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The field experiment was conducted during winter (rabi) 2020–21 and rainy (kharif) season of 2021–22 at College of Agriculture (University of Agricultural Sciences, Dharwad), Vijayapura, Karnataka to evaluate efficacy of bio-rationals against citrus leaf miner (Phyllocnistis citrella Stainton). The experiment was conducted in a randomized block design (RBD) with 8 treatments, viz. bio digester solution (10%); pongamia leaf extract (5%); Prosopis juliflora leaf extract (5%); Beauveria bassiana (2 × 108 conidia/g) (1 kg/ha); Bacillus thuringiensis 8 L (1 L/ha); neem-based insecticide (10000 ppm)
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20

Kipps, T. J., A. Österborg, J. Mayer, et al. "Clinical improvement with a novel CD20 mAb, ofatumumab, in fludarabine-refractory chronic lymphocytic leukemia (CLL) also refractory to alemtuzumab or with bulky lymphadenopathy." Journal of Clinical Oncology 27, no. 15_suppl (2009): 7043. http://dx.doi.org/10.1200/jco.2009.27.15_suppl.7043.

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7043 Background: Patients (pts) with CLL refractory tofludarabine and alemtuzumab (double-refractory, DR) or refractory to fludarabine with bulky (>5 cm) lymphadenopathy (bulky fludarabine-refractory, BFR) have a poor prognosis. Ofatumumab is a human mAb specific for a distinctive small-loop epitope of CD20 that appears more potent than rituximab in eliciting complement-dependent lysis of B cells in vitro. We report, for the first time, results from the planned interim analysis of the clinical benefit observed in pts with DR or BFR CLL treated with ofatumumab in an international pivotal cli
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21

Davis, Andrew A., Wade Thomas Iams, David Chan, et al. "A prospective study tracking longitudinal changes in genome-wide cell-free DNA (cfDNA) methylation to identify early nonresponders to cancer treatment." Journal of Clinical Oncology 37, no. 15_suppl (2019): 3042. http://dx.doi.org/10.1200/jco.2019.37.15_suppl.3042.

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3042 Background: Methylation is an epigenetic modification linked to cancer pathogenesis. The aim was to determine if changes in cfDNA methylation patterns before and after initiation of treatment could predict non-response to treatment prior to routine imaging and clinical follow-up. Methods: We prospectively collected clinical data and blood from 28 patients with metastatic malignancies (13 lung, 11 breast, 4 other). Blood was drawn prior to start of a new treatment, after first cycle (median 30 days), and/or second cycle (median 57 days). We performed whole-genome (WG) bisulfite sequencing
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22

Śmierzchalski-Wachocz, Dariusz. "The clergy of the Gorzow (Gorzów) Church repressed under the penal-administrative procedure. A historical analysis on the example of the Statement of Office “C” of the Ministry of the Interior from the years 1945–1963. Outline of the issues." Studia Koszalińsko-Kołobrzeskie 31 (2024): 193–224. https://doi.org/10.18276/skk.2024.31-11.

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Po II wojnie światowej komunistyczny aparat bezpieczeństwa szantażował, prześladował i mordował księży stawiających opór wobec ekipy rządowej. W każdym procesie politycznym przeciw obywatelom Polski na ławie oskarżonych zasiadał jakiś ksiądz lub inny duchowny. Oprócz zarzutów podżegania do wojny modne były oskarżenia o deprawacje moralne młodzieży i dzieci, o defraudację, o próby obalenia ustroju, o szpiegostwo na rzecz obcego wywiadu itp. W zasobie Biura Udostępniania i Archiwizacji Dokumentów Oddziału Instytutu Pamięci Narodowej w Warszawie przechowywany jest zbiór dokumentów liczący 37 kart
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23

Moreno, Carol, Neus Villamor, Jordi Esteve, et al. "Clinical Significance of Minimal Residual Disease (MRD), as Assessed by Different Techniques, after Stem Cell Transplantation (SCT) for Chronic Lymphocytic Leukemia (CLL)." Blood 106, no. 11 (2005): 2018. http://dx.doi.org/10.1182/blood.v106.11.2018.2018.

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Abstract MRD detection has been associated with a higher relapse risk in patients with CLL having achieved complete response (CR) by conventional NCI-WG criteria. Although there are a number of techniques to evaluate MRD, their respective clinical value is still controversial. Against this background, we analyzed MRD, as assessed by consensus PCR, real time quantitative PCR (qPCR), and flow cytometry, in peripheral blood (PB) and/or bone marrow (BM) in 40 patients with CLL submitted to SCT (25 autologous and 15 allogeneic). Patients were considered MRD positive if a monoclonal pattern was obta
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J.O, Alagbe,, Oluwafemi R.A, and Halima Abdullahi. "Effect of Dietary Inclusion of Ginger and Garlic Oil Mixture on the Growth Performance and Caecal Microbial Population of Broiler Chickens." International Journal of Clinical Case Reports and Reviews 8, no. 5 (2021): 01–05. http://dx.doi.org/10.31579/2690-4861/161.

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The objective of the present study was to determine effect of dietary inclusion of (Zingiber officinale) and garlic (Allium sativum) oil mixture (GIGM) on the growth performance and caecal microbial population of broiler chickens. One hundred and fifty one-day-old broiler chicks (Ross 308) were randomly allocated into 5 treatments with three replicates consisting of 10 birds each in a completely randomized design. Birds in treatment 1 (T1) was fed basal diet with 0 % inclusion of GIGM while T2, T3, T4 and T5 were given 0.1 %, 0.2 %, 0.3 % and 0.4 % respectively. Clean feed and water were offer
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GUEVARA-GONZÁLEZ, J. A., R. MOUHBI, J. M. ARROYO, M. R. ALVIR, and J. GONZÁLEZ. "Effects of correcting for microbial contamination and the use of sodium sulphite in neutral detergent fibre analyses on the ruminal fibre degradability of several feeds." Journal of Agricultural Science 153, no. 2 (2014): 361–70. http://dx.doi.org/10.1017/s0021859614000513.

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SUMMARYSodium sulphite is used in an optional way to remove insoluble proteins from neutral detergent fibre (NDF) residue. To determine whether the recovery of both NDF and insoluble nitrogen (N) in NDF solution (NDIN) are altered by its use, both parameters were measured in a set of 12 feeds, including cereal grains: maize (MG), rye (RG) and wheat (WG); cereal co-products: maize gluten feed (MGF), distilled dried grains from barley (DDGB) and wheat (DDGW) and wheat bran (WB); protein concentrates: rapeseed meal (RSM) and expeller palm kernel (EPK); dehydrated sugar beet pulp (DBP) and oat (OH
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Greer, Felicia, Jacobo Morales, and Michael Coles. "Wingate performance and surface EMG frequency variables are not affected by caffeine ingestion." Applied Physiology, Nutrition, and Metabolism 31, no. 5 (2006): 597–603. http://dx.doi.org/10.1139/h06-030.

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The ergogenic effect of caffeine and its mechanism of action on short-term, high-intensity exercise are controversial. One proposed mechanism is caffeine’s stimulatory effect on the central nervous system and thus, motor-unit excitation. The latter is non-invasively determined from surface electromyographic signal (EMG) frequency measures. The purpose of this study was to determine if power output and surface EMG frequency variables during high-intensity cycling were altered following caffeine ingestion. Eighteen recreationally active college males (mean ± SD age, 21.5 ± 1.8 y; height, 181.8 ±
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Ghadirinejad, Nickyar, Fredric Ottermo, Raheleh Nowzari, Naif Alsaadi, and Mazyar Ghadiri Nejad. "Optimizing a Green and Sustainable Off-Grid Energy-System Design: A Real Case." Sustainability 15, no. 17 (2023): 12800. http://dx.doi.org/10.3390/su151712800.

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In recent years, unquestionable warnings like the negative effects of CO2 emissions, the necessity of utilizing sustainable energy sources, and the rising demand for municipal electrification have been issued. Therefore, users are encouraged to provide off-grid and sustainable energy systems for their own homes and businesses, especially if they are located rurally and far from grids. Hence, this study aims to design an off-grid hybrid energy system, in order to minimize both the baseline cost of energy and the net current expenditure in the desired system. To construct such a system, wind gen
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Sacha, Dariusz, Agnieszka Skibińska, and Wojciech Krasodomski. "Analiza możliwości wykorzystania aparatu PetroOxy do oznaczania stabilności termooksydacyjnej smarów plastycznych metodą RSSOT (Rapid Small-Scale Oxidation Test)." Nafta-Gaz 78, no. 4 (2022): 299–311. http://dx.doi.org/10.18668/ng.2022.04.06.

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W warunkach eksploatacji smar podlega działaniu szeregu czynników, które powodują jego destrukcję. Smar spełniający swoje podstawowe funkcje w układzie smarowania narażony jest przede wszystkim na działanie wysokiej temperatury, a dominującym procesem starzenia, bezpośrednio wpływającym na okres użytkowania smaru, jest utlenianie. Stabilność termooksydacyjna ma decydujący wpływ na jakość i długość czasu pracy smarów w węzłach tarcia i układach smarowania. W 2018 r. ukazała się nowa procedura badawcza określająca stabilność oksydacyjną smarów plastycznych według normy ASTM D8206 (Standardowa me
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Helal, M. Rezuana Binte, and Shamim Shamsi. "In Vitro Screening of Fungicides and Plant Extracts Against Pathogenic Fungi Associated With Infected Fruits of Carica Papaya L." Journal of Bangladesh Academy of Sciences 42, no. 2 (2018): 121–28. http://dx.doi.org/10.3329/jbas.v42i2.40039.

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Five fungicides viz., Autostin 50 WDG, Dithane M 45, Greengel 72 WP, Ridomil Gold MZ 68 WG and Tilt 250 EC exclusively were tested against three pathogenic fungi viz., Colletotrichum gloeosporioides (Penz.) Sacc., Fusarium nivale (Fr.) Ces. and Fusarium sp. associated with Carica papaya L. following poisoned food technique. At 100 ppm Autostin showed complete growth inhibition of C. gloeosporioides, F. nivale and Fusarium sp., while Tilt 250 EC showed complete growth inhibition of C. gloeosporioides at the same concentration. These fungicides at 400 and 500 ppm showed complete growth inhibitio
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30

Stonys, Ričardas, and Dalius Vitkus. "Assessing Non-Laboratory Healthcare Professionals’ Attitude towards the Importance of Patient Preparation for Laboratory Tests." Healthcare 12, no. 10 (2024): 989. http://dx.doi.org/10.3390/healthcare12100989.

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(1) Background: Various guidelines address patient preparation and its importance for venous blood sampling, such as the GP41 guideline issued by the Clinical Laboratory Standards Institute (CLSI) and the blood collection guidelines published by the World Health Organisation. Recommendations provided by national societies or international organisations in the field of radiology, such as The Contrast Media Safety Committee of the European Society of Urogenital Radiology, or in the field of laboratory medicine, such as the Working Group for Preanalytical Phase (WG-PRE) of the European Federation
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31

Thum, Gregor, Maria Grazia Cappai, Ralf Bochert, Hendrik Schubert, and Petra Wolf. "Nutrient Profile of Baltic Coastal Red Algae (Delesseria sanguinea), Baltic Blue Mussel (Mytilus spp.) and King Ragworm (Alitta virens) as Potential Feed Material in the Diet of Rainbow Trout (Oncorhynchus mykiss Walbaum, 1792): A Preliminary Assessment." Agriculture 12, no. 2 (2022): 196. http://dx.doi.org/10.3390/agriculture12020196.

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The use of selected Baltic coastal organisms as potential alternative feed material in the formulation of rainbow trout diets was studied. German coastal water organisms (Delesseria sanguinea, seaweed red algae (A); Mytilus spp., Baltic blue mussel (M); Alitta virens, king ragworm (W)) were analyzed for nutrient, amino acid and mineral composition, and tested in comparative feeding trials. Five dietary treatments were supplied to a total of 165 juvenile rainbow trout (778 ± 111 g) for 75 days, allotted in 15 special brackish (3–5 practical salinity units (PSU)) water basins consisting of 11 fi
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32

Rondon, Gabriela, Rima M. Saliba, Julianne Chen, et al. "Fluid Overload As New Toxicity Category Has a Strong Impact on Non Relapse Mortality and Survival in Allogeneic Hematopoietic Stem Cell Transplantation." Blood 126, no. 23 (2015): 4321. http://dx.doi.org/10.1182/blood.v126.23.4321.4321.

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Abstract Background: Fluid retention/overload (FO) is common during hospitalization for allogeneic stem cell transplantation (ASCT) and is associated with weight gain (WG), edema, and other symptoms such as shortness of breath. It is unknown if symptomatic FO impacts transplant outcomes. We hypothesized that FO is associated with non-relapse mortality (NRM) and worse survival after ASCT. Methods: FO was scored by an independent team using the following criteria: grade 1 - asymptomatic weight gain <10% from baseline requiring occasional diuretics; grade 2 -symptomatic and or WG 10%-20% from
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33

Robak, Tadeusz, Anna Dmoszynska, Raouf Fetni, et al. "Incidence of Genomic Aberrations and Associated Efficacy from a Phase III Study Comparing Alemtuzumab (CAMPATH®, MABCAMPATH®) vs Chlorambucil as First Line Therapy for B-Cell Chronic Lymphocytic Leukemia (BCLL)." Blood 108, no. 11 (2006): 2092. http://dx.doi.org/10.1182/blood.v108.11.2092.2092.

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Abstract CAM307 is a randomized Phase III trial comparing the efficacy and safety of alemtuzumab (CAM) with chlorambucil (CHLO). The trial enrolled 297 previously untreated patients (pts) requiring therapy according to NCI-WG criteria. Pts were randomized 1:1 to CAM (n=149) vs CHLO (n=148) using standard dosing regimens. Fluorescence in situ hybridization (FISH) on interphase nuclei of lymphocytes isolated from blood was analyzed for cytogenetic abnormalities prior to the start of therapy. FISH analysis was performed using 13 DNA probes to detect chromosomal aberrations in 17p13.1 (P53), 13q14
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34

Hull, Larry A. "Apple, Concentrate and Dilute Acaricide Evaluation Test, 1992." Insecticide and Acaricide Tests 18, no. 1 (1993): 42–43. http://dx.doi.org/10.1093/iat/18.1.42.

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Abstract Treatments were applied to single-tree plots in a randomized block design consisting of 3 replicates of ‘Yorking’ and 2 replicates of ‘Golden Delicious’. Trees were planted to a spacing of 20 x 20 ft and were 19 years old. All treatments were applied with a Myers Mity Mist sprayer calibrated to deliver 100 gal/acre, driven at 2 mph, except for HHE-3736 70 WG and Savey 50 WP which were applied dilute to run-off with a high pressure handgun at approximately 4 gal of spray per tree. Application dates varied between treatments and are as listed in the tables. All plots received a regular
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35

Wierda, William G., Januario Castro, Robier A. Aguillon, et al. "Active Immune Gene Therapy Using ISF35: Responses Associated with Priming for Death Receptor-Induced Apoptosis and Sensitivity to Fludarabine in Patients with CLL and Del 17p." Blood 112, no. 11 (2008): 3530. http://dx.doi.org/10.1182/blood.v112.11.3530.3530.

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Abstract CLL cells can be transduced with adenovirus vector to express CD40-ligand (CD154). Ad-ISF35 is the Ad-vector that encodes a novel molecule capable of ligating CD40 on CLL cells. We conducted a phase I clinical trial to evaluate tolerability, toxicities, and clinical activity of a single infusion of autologous ISF35-transduced CLL cells. Doses of 1×108, 3×108, and 1×109 transduced cells were administered. Three patients (pts) were treated at each dose level. All pts had active disease with an NCI-WG ‘96 indication for treatment, 2 were previously untreated and 7 were previously treated
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36

Serhyenko, V., and O. Shyta. "Weed control in maize crops with various schemes of herbicide application." Interdepartmental Thematic Scientific Collection of Plant Protection and Quarantine, no. 67 (December 20, 2021): 196–211. http://dx.doi.org/10.36495/1606-9773.2021.67.196-211.

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Goal. Carry out a comparative evaluation of the effectiveness of different schemes of application of modern herbicides in maize crops.
 Methods. Field, phenological, statistical. Conducted spraying of corn crops to seedlings (ВВСН 00) with herbicides Adengo 465 SC, hp (thiencarbazone-methyl, 90 g/l + isoxaflutol, 225 g/l + cyprosulfamide, 150 g/l), 0.5 l/ha, Primextra TZ Gold 500 SC, (S-metachlor. 312.5 g/l + terbuthylazine, 187.5 g/l), 4.5 l/ ha, Merlin Flex Duo 475 SC, (isoxaflutop, 50 g/l + cyprosulfamide, 50 g/l + terbuthylazine, 375 g/l, 2.0 l/ha. After germination in the phase of 4—
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37

Robak, Tadeusz, Jerzy Z. Blonski, Krzysztof Jamroziak, et al. "Randomized Comparison of Cladribine Plus Cyclophosphamide with Fludarabine Plus Cyclophosphamde in Untreated Patients with Chronic Lymphocytic Leukemia: Report of the Polish Adult Leukemia Group (PALG-CLL3)." Blood 112, no. 11 (2008): 2103. http://dx.doi.org/10.1182/blood.v112.11.2103.2103.

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Abstract Purine nucleoside analogues, cladribine(2-CdA) and fludarabine (FA), especially combined with cyclophosphamide (CY) are potent cytotoxic drugs for the treatment of chronic lymphocytic leukemia (CLL). In this randomized study we aimed to establish whether combination of 2-CdA plus CY (CC) with FA plus (FC) provide similar benefit to previously untreated patients with CLL. The trial was started in January 2004 and the recruitment was ended in May 2007. The study primary endpoints were overall response (OR) and complete response (CR). The secondary endpoints included progression free sur
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38

Janakiram, Murali, and Timothy E. O’Brien. "Pegfilgrastim Use and Risk of Bleomycin Induced Pulmonary Toxicity in Hodgkin Lymphoma." Blood 112, no. 11 (2008): 4950. http://dx.doi.org/10.1182/blood.v112.11.4950.4950.

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Abstract Background Filgrastim may increase the risk of bleomycin induced pulmonary toxicity (BPT) in Hodgkin lymphoma patients, particularly those >age 40 [Martin WG, J Clin Onc, 2005; 23(30): 7614]. It is not clear if pegylated filgrastim, with a longer 1/2 life and delayed onset of action, also increases this risk. Methods: 38 cases of Hodgkin lymphoma treated with a bleomycin containing regimen were included in this analysis. 29 of these pts (Group A) also received pegfilgrastim and 9 pts (Group B) did not receive any growth factor support. All of the patients who received pegfilgra
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39

Bartalucci, Niccolò, Francesco Mannelli, Danilo Tarantino, et al. "Identification of Genomic Structural Variants (SVs) with Adverse Prognostic Significance in Normal-Karyotype (nk) Acute Myeloid Leukemia (AML) Patients." Blood 144, Supplement 1 (2024): 65. https://doi.org/10.1182/blood-2024-198342.

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Background: nkAML accounts for 40% of all AML. Although nkAML pts are included into favorable (fav) and intermediate (int) European Leukemia Net (ELN2022) risk category, the outcome is highly heterogeneous, and poses therapeutic challenges particularly as regards indication to stem cell transplant (SCT). Aim: To improve ELN-based prognostication, we characterized genomic SVs in nkAML pts through Long-Read Whole Genome Sequencing (WG-LRS). Methods: A total of 311 intensively treated nkAML pts were included; a discovery cohort (DC) was made up of 162 pts from the prospective NILG 02/06 and GIMEM
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Wierda, William G., Thomas J. Kipps, Jiri Mayer, et al. "Final Analysis From the International Trial of Single-Agent Ofatumumab In Patients with Fludarabine-Refractory Chronic Lymphocytic Leukemia." Blood 116, no. 21 (2010): 921. http://dx.doi.org/10.1182/blood.v116.21.921.921.

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Abstract Abstract 921 Background: Patients with chronic lymphocytic leukemia (CLL) refractory to fludarabine and alemtuzumab (FA-ref) or refractory to fludarabine with bulky (>5 cm) lymphadenopathy (BF-ref) have poor prognosis with salvage regimens (Tam et al. Leuk Lymphoma 2007). Ofatumumab, a human CD20 monoclonal antibody, was recently approved by the US FDA and EMEA for treatment of CLL refractory to fludarabine and alemtuzumab based on the interim analysis of the pivotal international clinical trial, which included data from 138 patients with FA-ref and BF-ref CLL. At the interim analy
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41

Ciccone, Maria, Candida Vitale, Christina Hinojosa, et al. "Early Results of a Phase II Study of Ofatumumab As Front-Line Treatment in Elderly, Unfit Patients with Chronic Lymphocytic Leukemia (CLL)." Blood 124, no. 21 (2014): 5656. http://dx.doi.org/10.1182/blood.v124.21.5656.5656.

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Abstract Background Patients with chronic lymphocytic leukemia (CLL) that are elderly and have multiple comorbidities show poor tolerance to chemoimmunotherapy. This population is frequent in the real-world clinical practice, but is usually excluded from participating in clinical trials. We, therefore, decided to investigate the activity and toxicity of ofatumumab, a fully human anti-CD20 monoclonal antibody in elderly unfit patients. Methods Patients with untreated CLL requiring therapy (2008 NCI-WG guidelines), aged ≥65 years, who had an ECOG performance status of 2-3 or ECOG 0-1 and a Charl
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42

Kay, Neil E., Wenting Wu, John C. Byrd, et al. "Cyclophosphamide Remains An Important Component of Treatment in CLL Patients Receiving Pentostatin and Rituximab Based Chemoimmunotherapy." Blood 112, no. 11 (2008): 43. http://dx.doi.org/10.1182/blood.v112.11.43.43.

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Abstract BACKGROUND: We have previously studied and reported that the combination of pentostatin (P, 2 mg/m2), cyclophosphamide (C 600 mg/m2) and rituximab (R 375 mg/m2) in previously untreated CLL is highly effective with an overall response (OR) rate of over 90% and a complete response rate (CR) of 41% (Blood109:405–411, 2007). We also found that this regimen can be effective even in older patients (>70 y), those with elevated beta-2 microglobulin levels, and patients with mildly reduced creatinine clearances (Cancer. 109:2291–2298, 2007). To determine whether similar benefit could be
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43

Shanafelt, Tait D., Mark C. Lanasa, Clive S. Zent, et al. "Ofatumumab Based Chemoimmunotherapy (CIT) for Patients with Previously Untreated CLL,." Blood 118, no. 21 (2011): 3898. http://dx.doi.org/10.1182/blood.v118.21.3898.3898.

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Abstract Abstract 3898 Background: Although chemoimmunotherapy (CIT) has substantially improved response rates, treatment free survival, and overall survival in patients with chronic lymphocytic leukemia (CLL), only 4050 of patients achieve a complete remission and the majority have residual disease when evaluated using sensitive assays. There remains interest in identifying new approaches to improve the effectiveness of CIT. Ofatumumab is a humanized anti-CD20 monoclonal antibody that is approved for patients with relapsed CLL refractory to fludarabine and alemtuzumab. The single agent activi
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44

Montillo, Marco, Francesca Ricci, Alessandra Tedeschi, et al. "Impact on Progression Free Survival of Autologous Stem Cell transplantation after Consolidation with Alemtuzumab in Chronic Lymphocytic Leukemia." Blood 112, no. 11 (2008): 2182. http://dx.doi.org/10.1182/blood.v112.11.2182.2182.

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Abstract The role of an intensified program of autologous stem cell transplantation (ASCT) following a consolidation phase with alemtuzumab (A) in pts with chronic lymphocytic leukemia (B-CLL) who received a fludarabine-based regimen (Fbr) as debulking is still considered questionable. The reported evidence of a prolonged treatment free-survival and survival associated to the absence of minimal residual disease (MRD) in B-CLL pts treated with A doesn’t seem to justify an intensification with ASCT in case of MRD-. We have already reported our experience in B-CLL pts treated with Fbr who after a
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45

Ami, R. Lokhandwala, and R. Bora Madhumati. "CHANGES ACQUIRED IN PEROXIDASE –A KEY MARKER IN PLANT DEFENSE; UPON ROOT TO ROOT TRANSFER OF GLOMUS GEOSPORUM TO LYCOPERSICON ESCULENTUM MILL." Biolife 2, no. 4 (2022): 1050–59. https://doi.org/10.5281/zenodo.7233142.

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<strong>ABSTRACT</strong> Plant defense responses are strongly stimulated by AM fungi in host plants by control over defense gene expression during establishment of a successful functional symbiosis. Peroxidase requiring compounds are laid down on cell wall as barrier against microbial incursion thus can be used as an indicator in plant defense responses. In the present study, activity and expression of peroxidase was monitored in <em>Glomus geosporum</em> (transferred from roots of <em>Cyperus rotundus</em>) colonized and uncolonized two-weeks-old <em>Lycopersicon esculentum</em> Mill seedlin
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46

Geyer, Mark Blaine, Jae H. Park, Isabelle Riviere, et al. "Implications of Concurrent Ibrutinib Therapy on CAR T-Cell Manufacturing and Phenotype and on Clinical Outcomes Following CD19-Targeted CAR T-Cell Administration in Adults with Relapsed/Refractory CLL." Blood 128, no. 22 (2016): 58. http://dx.doi.org/10.1182/blood.v128.22.58.58.

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Abstract Introduction: CD19-targeted chimeric antigen receptor-modified (CAR) T cells have demonstrated considerable therapeutic efficacy in patients (pts) with relapsed and/or refractory (R/R) B cell ALL (B-ALL), resulting in rapid and often durable complete responses (CR). In contrast, a smaller subset of pts with R/R CLL have achieved CR following CD19-targeted CAR T cell therapy. Ibrutinib (IBR), which has considerable efficacy as a single agent in pts with R/R CLL, may modulate antitumor T cell immune responses. Others have observed enhanced ex vivo expansion of autologous T cells collect
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Ross, L., D. Hansen, S. Proudman, et al. "OP0235 DEVELOPMENT AND PRELIMINARY VALIDATION OF THE NOVEL SCLERODERMA CLINICAL TRIALS CONSORTIUM ACTIVITY INDEX." Annals of the Rheumatic Diseases 82, Suppl 1 (2023): 155–56. http://dx.doi.org/10.1136/annrheumdis-2023-eular.1239.

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BackgroundAccurate measurement of disease activity in systemic sclerosis (SSc) remains a significant challenge. Previous activity indices have been criticised for limitations of face and content validity.ObjectivesThe Scleroderma Clinical Trials Consortium (SCTC) convened an Activity Index Working Group to develop a disease activity index (SCTC AI) that has face, content and construct validity.MethodsConsensus was reached regarding the conceptual definition of disease activity in SSc. All SCTC AI items were required to be measures of the agreed upon construct.See Figure 1 for process of item g
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48

Wierda, W. G., T. Kipps, J. Mayer, et al. "Activity of ofatumumab, a novel CD20 mAb, and prior rituximab exposure in patients with fludarabine- and alemtuzumab-refractory or bulky fludarabine-refractory chronic lymphocytic leukemia (CLL)." Journal of Clinical Oncology 27, no. 15_suppl (2009): 7044. http://dx.doi.org/10.1200/jco.2009.27.15_suppl.7044.

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7044^ Background: Salvage therapy has limited activity (20–26% overall response rate [ORR]) in patients (pts) with CLL refractory to fludarabine and alemtuzumab (double-refractory, DR) or refractory to fludarabine with bulky (&gt;5 cm) lymphadenopathy (bulky fludarabine-refractory, BFR). Ofatumumab (OFA) is a fully human mAb that targets a unique small-loop epitope of CD20 close to the cell surface and elicits more potent in vitro complement-dependent cytotoxicity of B-cell lines and tumor cells vs rituximab (RTX). To determine whether prior RTX exposure impacted activity of OFA in pts with DR
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49

Yeh, Albert, Madan Jagasia, Kimberly Dahlman, et al. "Cytomegalovirus Promotes Aberrant Memory CD4 T Cell Differentiation and Immune Function after Allogeneic Stem Cell Transplantation." Blood 136, Supplement 1 (2020): 15–16. http://dx.doi.org/10.1182/blood-2020-134829.

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Background: Cytomegalovirus (CMV) serostatus is associated with transplant related mortality, relapse and survival following allogeneic stem cell transplant (SCT). Prior studies have demonstrated that CMV seronegative recipients (R-) receiving a CMV seropositive graft (D+) experience inferior outcomes compared to the R-/D- combination, an observation that is independent of viral reactivation and due to increased bacterial and fungal sepsis (Nichols WG et al, J. Infect. Dis. 2002; 185:273-82). We therefore investigated the hypothesis that CMV exposure, including that by the donor only prior to
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Mostoviak, S., I. Mostoviak, O. Borzykh, and V. Fedorenko. "Ecotoxicological assessment of the application of chemical products of plant protection against pests." Karantin i zahist roslin, no. 3 (September 26, 2022): 3–10. http://dx.doi.org/10.36495/2312-0614.2022.3.3-10.

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Goal. To analyze the number of insecticides and acaricides during the cultivation of crops in Ukraine and in the central part of the Right Bank Forest-Steppe of Ukraine and to determine the degree of danger of their application.&#x0D; Methods. Analytical, economic and statistical, comparative analysis. The analysis of the amount of chemical plant protection products for 2018—2020 was conducted according to the State Statistics Service of Ukraine. Ecotoxicological assessment of 23 chemicals was performed using the Methodologies of the Institute of Plant Protection of NAAS of Ukraine according t
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