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1

Sadou, Amel. "Cross-talk between ral and rac pathways in the control of cell migration." Thesis, Paris 11, 2012. http://www.theses.fr/2012PA11T010.

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Le mode de coordination parmi les différentes molécules qui régulent la migration reste très peu connu. Ce travail traite de deux voies de transduction régulant la migration: la voie Rac1/WRC (Wave Regulatory Complex) qui contrôle la formation du réseau d’actine au front des cellules migrantes, et la voie RalB/exocyst, dont les mécanismes moléculaires de son implication dans la motilité cellulaire étaient inconnus au début de cette thèse. Rac1 et RalB sont des petites protéines G des familles Rho et Ras, respectivement. Les complexes WRC et exocyst sont leurs effecteurs directs.Au cours de la
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Silva, Gilsomar Gabriel da. "A influência das reclamações dos condicionadores WRAC na satisfação dos clientes." reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2002. http://hdl.handle.net/10183/184342.

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As organizações com o objetivo de ser cada vez mais competitivas em um mundo globalizado e extremamente competitivo buscam oferecer produtos e serviços que agreguem valor aos seus clientes, aumentando, assim, sua satisfação. A insatisfação dos clientes, especificamente, tem se mostrado de grande importância, pelos seus impactos negativos no desempenho econômico de médio e longo prazo nos resultados das empresas, e não nos seus aspectos de curto prazo. Este trabalho se constituiu na realização de uma pesquisa descritiva sobre a satisfação dos consumidores de condicionadores de ar tipo WRAC da S
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3

Zago, Giulia. "Lighting up Invasion with Optogenetics : RalB Mobilizes the WRC Complex Downstream Ras." Thesis, Université Paris-Saclay (ComUE), 2018. http://www.theses.fr/2018SACLS333.

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La formation des métastases est un processus multi étapes à travers lequel les cellules cancéreuses se détachent de la tumeur primaire pour envahir à distance dans un site secondaire. L’acquisition de capacités migratoires et invasives des cellules tumorales est cruciale dans la cascade métastatique. L'activation mutationnelle des protéines Ras favorise l'oncogenèse en perturbant une multitude de molécules et de voies qui sont impliquées dans la régulation de plusieurs processus, y compris l'invasion cellulaire et la motilité. Les petites Rho GTPases (Rac1, Cdc42 et RhoA)jouent un rôle central
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Sadou, Amel. "Connexions entre les voies ral et rac dans le contrôle de la migration cellulaire." Phd thesis, Université Paris Sud - Paris XI, 2012. http://tel.archives-ouvertes.fr/tel-00701484.

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Le mode de coordination parmi les différentes molécules qui régulent la migration reste très peu connu. Ce travail traite de deux voies de transduction régulant la migration: la voie Rac1/WRC (Wave Regulatory Complex) qui contrôle la formation du réseau d'actine au front des cellules migrantes, et la voie RalB/exocyst, dont les mécanismes moléculaires de son implication dans la motilité cellulaire étaient inconnus au début de cette thèse. Rac1 et RalB sont des petites protéines G des familles Rho et Ras, respectivement. Les complexes WRC et exocyst sont leurs effecteurs directs.Au cours de la
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Arriagada, Martínez Felipe Andrés. "Análisis de carga sobre boquillas en estanques y recipientes a presión (según ASME VIII) por el método WRC 107 y por método FEM." Tesis, Universidad de Chile, 2018. http://repositorio.uchile.cl/handle/2250/169945.

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Memoria para optar al título de Ingeniero Civil Mecánico<br>En Chile y en gran parte del mundo se utiliza el código ASME VIII, para el diseño, fabricación y montaje de recipientes a presión. Sin embargo, las reglas de montaje del piping, no suelen ser respetadas, provocando fallas en los equipos. Esto es de suma importancia en ingeniería ya que las empresas fabricantes son las responsables de entregar la memoria de cálculo correspondiente. En base a esto, el objetivo general de esta memoria consiste en calcular la capacidad de carga en las boquillas de recipientes a presión, debido a fue
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Guthrie, Sarah L. "Reality and Perception of Feminism and Broadcast, 1968-1977: The Mary Tyler Moore Show, Alison Owings, and the Experience of Second-Wave Feminism in Broadcast News." Ohio University / OhioLINK, 2010. http://rave.ohiolink.edu/etdc/view?acc_num=ohiou1274570051.

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Wang, Hao-Chung, and 汪皓中. "20-Gbps Transmission of Injection-Locked WRC-FPLD for WDM-PON." Thesis, 2012. http://ndltd.ncl.edu.tw/handle/39080112261556836750.

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碩士<br>國立交通大學<br>顯示科技研究所<br>100<br>Wavelength-division-multiplexing PONs (WDM-PONs) recently have been envisioned as prominent technology for next-generation PONs because of its high network security and it can provide great amount of users. How to keep the cost down and increase data transmission is the most important issue. In this thesis, we use the injection-locked weak-resonant-cavity Fabry-Perot laser diode (WRC-FPLD) at WDM-PON so that it can be used for colorless ONUs light source. We will show the WRC-FPLD with 1% front-facet reflectivity injected by a tunable laser and directly modula
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Steel, Emily C. "The Wisconsin wetlands reserve at ten a decade of wetland restoration under the WRP /." 2004. http://catalog.hathitrust.org/api/volumes/oclc/56205014.html.

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Thesis (M.S.)--University of Wisconsin--Madison, 2004.<br>Typescript. eContent provider-neutral record in process. Description based on print version record. Includes bibliographical references (leaves 129-135).
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Hsiao, Che-Jen, and 蕭哲仁. "The Study of Anticancer Mechanisms of WRC-213 and Mana-Hox in Human Prostate Cancer Cell Lines." Thesis, 2008. http://ndltd.ncl.edu.tw/handle/91138969323908564424.

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博士<br>國立清華大學<br>生命科學系<br>96<br>In the present studies, we elucidate the anticancer mechanism of WRC-213 and Mana-Hox in the androgen-refractory human prostate adenicarcinoma PC-3 cells. In the first part, the research is to investigate the apoptotic mechanism of WRC-213, an anthracenedione derivative, in human prostate cancer PC-3 cells. WRC-213 induced apoptotic cell death in PC-3 cells in a concentration- and time-dependent manner. WRC-213 induced DNA damage and inhibited activity of topoisomerase II, resulting in cell cycle arrest at S and G2 phase. After the checkpoint arrest, WRC-213 indu
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10

Lin, Chun-Ju, and 林俊儒. "Self-Triggered Harmonic Mode-Locking WRC-FPLD Based Synthesizer-Free 10 Gbit/s RZ Data Transmission System." Thesis, 2011. http://ndltd.ncl.edu.tw/handle/14226687783867834812.

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碩士<br>國立臺灣大學<br>光電工程學研究所<br>99<br>A self-triggered harmonic mode-locked weak-resonant-cavity Fabry-Perot laser diode is employed as the 10 Gbit/s RZ data generator. Derived from the rate equation, the pulsewidth formula in actively mode-locking theory is modified and illuminates the shortening of the pulse as a function of optical feedback ratio and microwave power gain. The pulsewidth is narrower with higher optical injection and microwave gain due to the gain saturation of the laser diode and the increase of the modulation depth. The timing jitter, pulsewidth of the pulse train and phase n
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Lee, Yi-Cheng, and 李宜錚. "Investigation on 10 GHz Self-Feedback Mode-Locking Dynamics of a Directly-Modulated WRC-FPLD Fiber Laser." Thesis, 2011. http://ndltd.ncl.edu.tw/handle/57239833786857908664.

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碩士<br>國立臺灣大學<br>光電工程學研究所<br>99<br>In this work, a novel designed fiber ring laser by self-feedback mode-locked weak-resonant-cavity Fabry-Perot laser diode (WRC-FPLD) is established. By directly-modulating, the WRC-FPLD is used simultaneously as the gain medium and the optical pulsed carrier source in the fiber ring. The characteristic of the 10 GHz mode-locked optical pulse-train beyond modulation bandwidth operation of the WRC-FPLD has been demonstrated. First, with 90% self-feedback ratio and 28 dBm modulation power via circulated fiber ring, the enhancement of mode-locked force can be
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12

Carlson, Benjamin Robert. "Linking WRP/srGAP3 to the Cognitive Deficits in 3p- Syndrome and Its Role in the Regulation of Dendritic Filopodia Formation." Diss., 2011. http://hdl.handle.net/10161/5031.

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<p>Rho GTPase signaling regulates a wide variety of cellular functions in the developing and adult central nervous system. These molecular switches are in turn spatially and temporally regulated by an over abundance of positive and negative regulatory proteins: the activating guanine nucleotide exchange factors (GEFs) and the deactivating GTPase activating proteins (GAPs). The WAVE-associated Rac GAP (WRP) is thought to regulate key aspects of synapse development and function, and has been implicated in a form of mental retardation in humans called 3p- Syndrome. WRP is a member of the srGA
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13

Cheng, Min-Chi, and 鄭民奇. "36 Gbit/s 16-QAM OFDM data transmission in DWDM-PON with a directly modulated and injection-locked WRC-FPLD." Thesis, 2014. http://ndltd.ncl.edu.tw/handle/57044867845048563416.

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碩士<br>國立臺灣大學<br>光電工程學研究所<br>102<br>To build up a high-speed and low-cost optical access network, it is necessary to fuse a multiple carrier data format and a colorless transmitter based universal into the dense wavelength division multiplexing passive optical network (DWDM-PON) in the near future. The directly modulated transmission of optical 16 quadrature amplitude modulation (QAM) orthogonal frequency division multiplexing (OFDM) data-stream at its total bit rate up to 20 Gbit/s is demonstrated by up-shifting the relaxation oscillation peak and suppressing its relative intensity noise in a
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14

Santos, Ricardo André Cabaço. "Prova de varrimento de área em competição de veleiros com navegação autónoma." Master's thesis, 2019. http://hdl.handle.net/10362/125778.

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A competição internacional de veleiros autónomos WRSC (World Robotic Sailing Championship) realiza-se anualmente tentando reunir a comunidade académica ativa na área. Esta competição é composta por quatro provas, sendo que o objetivo desta dissertação foi implementar uma solução para uma delas: a prova de varrimento em área. Esta prova consiste em varrer uma área definida por bóias sinalizadoras e compostas por quadrículas, tendo uma duração máxima de 30 minutos. Cada quadrícula equivale a um ponto e é apurado o vencedor da prova que percorrer um maior número de quadrículas num período
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Manjeya, Nicolle Chido. "A contextual and transdisciplinary analysis of pedagogic, operational and administrative frameworks of a Writing Centre : the case of the Durban University of Technology (DUT) Writing Centre (WrC)." Thesis, 2017. http://hdl.handle.net/10321/2613.

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Submitted in fulfilment of the requirements of the Degree of Doctor of Philosophy: Public Management, 2017.<br>Different pedagogies, and writing styles have not only over the years transformed the face of academia, but have played a pivotal role in shaping diverse curricula and contributing to their development. In pursuit of attaining suitable models that have administrative and operational frameworks that address the ever-growing myriad multicultural world we live in today; different models and facilities have been developed to keep up with the development of academic literacies. The overall
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