Gotowe bibliografie tematyczne / Xanthines

Spis treści

  1. Artykuły w czasopismach
  2. Rozprawy doktorskie
  3. Książki
  4. Części książek
  5. Streszczenia konferencji
  6. Raporty organizacyjne

Gotowa bibliografia na temat „Xanthines”

Autor: Grafiati
Data publikacji: 4 czerwca 2021
Data aktualizacji: 25 lipca 2025

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Artykuły w czasopismach na temat "Xanthines"

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Inamoto, Kiyofumi, Maki Shimizu, Noboru Hayama, and Tetsutaro Kimachi. "Copper-Catalyzed Intramolecular C–H Amination: A New Entry to Substituted Xanthine Derivatives." Synthesis 49, no. 18 (2017): 4183–90. http://dx.doi.org/10.1055/s-0036-1588821.

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Catalytic synthesis of xanthines was achieved in the presence of a copper catalyst. The process involves copper-catalyzed intramolecular C–H amination of benzamidines that possess a uracil moiety and produces variously substituted xanthines generally in good to high yields. This work introduces a new, facile approach to polysubstituted xanthine compounds.
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Woziwodzka, Anna, Marta Krychowiak-Maśnicka, Grzegorz Gołuński, et al. "Modulatory Effects of Caffeine and Pentoxifylline on Aromatic Antibiotics: A Role for Hetero-Complex Formation." Molecules 26, no. 12 (2021): 3628. http://dx.doi.org/10.3390/molecules26123628.

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Antimicrobial resistance is a major healthcare threat globally. Xanthines, including caffeine and pentoxifylline, are attractive candidates for drug repurposing, given their well-established safety and pharmacological profiles. This study aimed to analyze potential interactions between xanthines and aromatic antibiotics (i.e., tetracycline and ciprofloxacin), and their impact on antibiotic antibacterial activity. UV-vis spectroscopy, statistical-thermodynamical modeling, and isothermal titration calorimetry were used to quantitatively evaluate xanthine-antibiotic interactions. The antibacteria
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GLOGOWSKI, JAN, DOUGLAS R. DANFORTH, and ANDRZEJ CIERESZKO. "Inhibition of Alkaline Phosphatase Activity of Boar Semen by Pentoxifylline, Caffeine, and Theophylline." Journal of Andrology 23, no. 6 (2002): 783–92. http://dx.doi.org/10.1002/j.1939-4640.2002.tb02334.x.

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ABSTRACT: Methyl xanthines have been used frequently as additives to sperm suspensions in order to improve sperm characteristics. The mechanism of action on spermatozoa is generally assumed to be inhibition of sperm phosphodiesterase activity, resulting in elevation of complementary adenosine monophosphate levels in spermatozoa. The present study was designed to examine the effect of methyl xanthines (pentoxifylline, caffeine, and theophylline) on another important enzyme system, alkaline phosphatase, in boar seminal plasma and spermatozoa. Inhibition of sperm alkaline phosphatase could be dis
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&NA;. "Xanthines see Ephedrine/xanthines." Reactions Weekly &NA;, no. 337 (1991): 8. http://dx.doi.org/10.2165/00128415-199103370-00055.

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Gibson, Christopher M., and Patrick W. Fowler. "Aromaticity of caffeine, xanthine and the dimethyl xanthines." Tetrahedron Letters 55, no. 13 (2014): 2078–81. http://dx.doi.org/10.1016/j.tetlet.2014.02.027.

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&NA;. "Xanthines." Reactions Weekly &NA;, no. 307 (1990): 8. http://dx.doi.org/10.2165/00128415-199003070-00041.

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Aleksandrova, K. V., Ye S. Pruhlo, Ye K. Mykhalchenko, O. S. Shkoda, and O. Yu Cherchesova. "Search for potential hypoglycemic agents among potassium salts of 3-benzyl-8-substituted xanthines." Current issues in pharmacy and medicine: science and practice 15, no. 3 (2022): 266–70. http://dx.doi.org/10.14739/2409-2932.2022.3.253385.

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Nowadays, the prevalence of metabolic syndrome (MS) is a serious problem among the world’s population. Metabolic syndrome includes the so-called “deadly” quartet – hypertension, type 2 diabetes mellitus (diabetes mellitus), dyslipidemia and alimentary obesity. After all, type 2 diabetes is included in the list of pathologies of the metabolic syndrome, it is important to find ways to alleviate the disease. Derivatives of such a heterocyclic system as xanthine are of great interest in this aspect. The aim of the study was to explore the hypoglycemic activity of newly synthesized water-soluble de
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Sánchez-Eleuterio, Alma, Carlos Mendoza-Merlos, Ricardo Corona Sánchez та ін. "Experimental and Theoretical Studies on Acid Corrosion Inhibition of API 5L X70 Steel with Novel 1-N-α-d-Glucopyranosyl-1H-1,2,3-Triazole Xanthines". Molecules 28, № 1 (2023): 460. http://dx.doi.org/10.3390/molecules28010460.

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A series of novel 1-N-α-d-glucopyranosyl-1H-1,2,3-triazole xanthines was synthesized from azido sugars (glucose, galactose, and lactose) and propargyl xanthines (theophylline and theobromine) using a typical copper (I)-catalyzed azide–alkyne 1,3-dipolar cycloaddition. The corrosion inhibition activities of these new carbohydrate-xanthine compounds were evaluated by studying the corrosion of API 5 L X70 steel in a 1 M HCl medium. The results showed that, at 10 ppm, a 90% inhibition efficiency was reached by electrochemical impedance spectroscopy. The inhibitory efficiency of these molecules is
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Cazzola, Mario, Luigino Calzetta, Peter J. Barnes, et al. "Efficacy and safety profile of xanthines in COPD: a network meta-analysis." European Respiratory Review 27, no. 148 (2018): 180010. http://dx.doi.org/10.1183/16000617.0010-2018.

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Theophylline can still have a role in the management of stable chronic obstructive pulmonary disease (COPD), but its use remains controversial, mainly due to its narrow therapeutic window. Doxofylline, another xanthine, is an effective bronchodilator and displays a better safety profile than theophylline. Therefore, we performed a quantitative synthesis to compare the efficacy and safety profile of different xanthines in COPD.The primary end-point of this meta-analysis was the impact of xanthines on lung function. In addition, we assessed the risk of adverse events by normalising data on safet
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&NA;. "Theophylline/xanthines." Reactions Weekly &NA;, no. 403 (1992): 8. http://dx.doi.org/10.2165/00128415-199204030-00031.

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Rozprawy doktorskie na temat "Xanthines"

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Riche, Christian. "Xanthines : approches analytique, clinique, métabolique." Besançon, 1988. http://www.theses.fr/1988BESAA001.

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A partir de techniques de dosage des bases xanthiques par chromatographie en phase gazeuse, sur colonne capillaire de verre, avec détection thermoionique, et par chromatographie liquide de haute performance sur colonne C18, utilisant un gradient de solvant, sont abordés des problèmes de pharmacologie clinique et de métabolisme in vivo et in vitro. L'utilisation de la théophylline et de la caféine dans le cadre du traitement des apnées du nouveau-né est étudiée. Deux expérimentations cliniques, destinées à déterminer la zone thérapeutique de la théophylline et de la caféine sont rapportées. Le
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Perticarari, Sofia. "Atropisomeric xanthines: Synthesis, stereodynamics and absolute configuration." Master's thesis, Alma Mater Studiorum - Università di Bologna, 2015. http://amslaurea.unibo.it/9025/.

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During the thesis period a new class of atropisomeric xanthine derivatives has been studied. We decided to focus our attention on these purine bases because of their various biological activities, that could play an important role in the discovery of new bioactive atropisomers. The synthesized compounds bear an Aryl-N chiral axis in position 1 of the xanthine scaffold, around which the rotation is prevented by the presence of bulky ortho substituents. Through a retro synthetic analysis we synthesized three atropisomeric structures bearing in position 1 of the purine scaffold respectively an o-
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Beauglehole, Anthony Robert, and anthony@adenrx com. "N3-substituted xanthines as irreversible adenosine receptor antagonists." Deakin University. School of Biological and Chemical Sciences, 2000. http://tux.lib.deakin.edu.au./adt-VDU/public/adt-VDU20080612.084330.

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8-Cyclopentyl-3-(3-(4-fluorosulfonylbenzoyl)oxy)propyl-propylxanthine (44, FSCPX) has been reported to exhibit potent and selective irreversible antagonism of the A1 adenosine receptor when using in vitro biological preparations. However, FSCPX (44) suffers from cleavage of the ester linkage separating the reactive 4-(fluorosulfonyl)phenyl moiety from the xanthine pharmacophore when used in in vivo biological preparations or preparations containing significant enzyme activity, presumably by esterases. Cleavage
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Duckworth, Megan Jane Medical Sciences Faculty of Medicine UNSW. "Characterisation of the xanthineguanine phosphoribosyltransferase of helicobacter pylori as a potential therapeutic target." Publisher:University of New South Wales. Medical Sciences, 2008. http://handle.unsw.edu.au/1959.4/43418.

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Helicobacter pylori infects more than half of the global population and causes gastric disorders. The increasing development of antibiotic resistance by the bacterium continues to limit treatment options. The identification and characterisation of novel therapeutic targets are necessary for successful future treatment of the infection. One potential target for therapeutic intervention is the gpt gene encoded by hp0735 (jhp0672) in H. pylori strain 26695 (J99). This gene produces a putative xanthine-guanine phosphoribosyltransferase (XGPRTase), an enzyme of the purine salvage synthesis pathway
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Kascatan, Nebioglu Aysegul. "N-HETEROCYCLIC CARBENE SILVER(I) COMPLEXES FROM XANTHINES AND THEIR ANTIMICROBIAL APPLICATIONS." University of Akron / OhioLINK, 2007. http://rave.ohiolink.edu/etdc/view?acc_num=akron1176579309.

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Massip, Stéphane. "Synthèse de nouvelles xanthines, dérivées de 2-amino-2-oxazolines, antagonistes potentiels des récepteurs de l'adenosine." Bordeaux 2, 2005. http://www.theses.fr/2005BOR21206.

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Ce travail de thèse nous a permis de synthétiser un grand nombre de nouveaux dérivés de type 1- ou 3-[2-hydroxy-3-aryloxypropyl]xanthines. Ces composés ont été obtenus à partir d'un synthon original de type amidine, les 2-amino-2-oxazolines. Les différentes voies réaxtionnelles nous ont conduit à des diaminouraciles intermédiaires diversement substitués dont les possibilités réactionnelles nous ont permis l'accès à plus de 60 nouvelles xanthines et analogues. Différentes stratégies de synthèse ont été développées pour accéder à de nouvelles xanthines 3 différemment substituées en position 1 et
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Seddon, Gavin M. "Radiation effects on biochemical systems." Thesis, University of Salford, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.313912.

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Mapengo, Raphaël. "Cinétiques de méthylation et de deutérométhylation des xanthines : évaluation des effets isotopiques : essai de corrélation aux réactions de N-déméthylation biologique." Lyon 1, 1990. http://www.theses.fr/1990LYO1T168.

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Calenzo, Chappe Valérie (19. "Régulation et pharmacologie du canal chlorure CFTR : implication des récepteurs purinergiques de type P2Y dans l'activation du canal CFTR par les dérivés xanthines." Aix-Marseille 1, 1999. http://www.theses.fr/1999AIX11026.

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Les epitheliums forment une barriere continue entre deux compartiments et permettent le transport d'ions, de solutes et de macromolecules. L'absorption de na + et la secretion de cl sont des elements majeurs de la fonction epitheliale. Le canal cftr (cystic fibrosis transmembrane conductance regulator), membre de la superfamille des transporteurs abc (atp binding cassette), est une des clefs de la regulation du transport de chlorure dans les epitheliums. La mucoviscidose est la maladie genetique la plus repandue dans les populations europeennes et nord-americaines. Elle se caracterise par une
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Essandoh, Ernest. "Structural studies of organic crystals of pharmaceutical relevance : correlation of crystal structure analysis with recognised non-bonded structural motifs in the organic solid state." Thesis, University of Bradford, 2009. http://hdl.handle.net/10454/4444.

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Pharmaceutical solids tend to exist in different physical forms termed as polymorphs. Issues about pharmaceutical systems are mainly concerned with the active ingredient's physico-chemical stability and bioavailability. The main aim of this study is to investigate the non-bonded interactions in pharmaceutical solids that govern the physical pharmaceutics performance of such materials and through the use of structural techniques and correlation of these results with crystal structural database to establish the presence of physical motifs in selected systems. Structural motifs were identified by
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Książki na temat "Xanthines"

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1946-, Barnes Peter J., ed. The Mechanism of action of Xanthines in respiratory disease. Royal Society of Medicine Services, 1988.

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Karl-Erik, Andersson, Persson C. G. A, and AB Draco, eds. Anti-asthma xanthines and adenosine: Proceedings of a symposium in Copenhagen, February 22-23, 1985. Excerpta Medica, 1985.

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Services, IBC Technical, ed. Xanthines: an update on their chemistry, pharmacology and therapeutics: Conference documentation : London, 1988. IBC TechnicalServices, 1988.

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1944-, Costello J. F., Piper Priscilla J, and Royal Society of Medicine (Great Britain). Respiratory Section., eds. Methylxanthines and phosphodiesterase inhibitors in the treatment of airways disease: The proceedings of a meeting held by the Respiratory Section of the Royal Society of Medicine, London, November 1993. Parthenon Pub. Group, 1994.

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International Workshop on Adenosine and Xanthine Derivatives (1984 Wiesbaden, Germany). Adenosine: Receptors and modulation of cell function : proceedings of the International Workshop on Adenosine and Xanthine derivatives. IRL Press, 1985.

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Nilson, G. The mountain vipers of the Middle East: The Vipera xanthina complex (Reptilia, Viperidae). Zoologisches Forschungsinstitut und Museum Alexander Koenig, 1986.

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Neish, William J. P. Xanthines and cancer. Aberdeen University Press, 1988.

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(Editor), K. E. Andersson, and C.G.A. Persson (Editor), eds. Anti-asthma Xanthines and Adenosine (Current clinical practice series). Elsevier, 1986.

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Neish, William J. P. Xanthines and Cancer: An Experimental Study of Tumour Inhibition. MacMillan Publishing Company, 1988.

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Xanthines and cancer: An experimental study of tumour inhibition. Aberdeen University Press, 1988.

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Części książek na temat "Xanthines"

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Schuckit, Marc A. "Xanthines (Caffeine) and Nicotine." In Drug and Alcohol Abuse. Springer US, 1989. http://dx.doi.org/10.1007/978-1-4757-0767-0_12.

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Schuckit, Marc A. "Xanthines (Caffeine) and Nicotine." In Drug and Alcohol Abuse. Springer US, 1995. http://dx.doi.org/10.1007/978-1-4757-2407-3_12.

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Schuckit, Marc A. "Xanthines (Caffeine) and Nicotine." In Drug and Alcohol Abuse. Springer US, 2000. http://dx.doi.org/10.1007/978-1-4757-3232-0_12.

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Tattersfield, Anne E., and Martin W. McNicol. "Theophylline and Related Xanthines." In Treatment in Clinical Medicine. Springer London, 1987. http://dx.doi.org/10.1007/978-1-4471-3132-8_17.

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Spina, D., and C. P. Page. "Xanthines and Phosphodiesterase Inhibitors." In Handbook of Experimental Pharmacology. Springer International Publishing, 2016. http://dx.doi.org/10.1007/164_2016_71.

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Müller, Christa E., and Kenneth A. Jacobson. "Xanthines as Adenosine Receptor Antagonists." In Methylxanthines. Springer Berlin Heidelberg, 2010. http://dx.doi.org/10.1007/978-3-642-13443-2_6.

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Persson, C. G. A., and R. Pauwels. "Pharmacology of Anti-Asthma Xanthines." In Pharmacology of Asthma. Springer Berlin Heidelberg, 1991. http://dx.doi.org/10.1007/978-3-642-75855-3_7.

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Favrod-Coune, Thierry, and Barbara Broers. "Addiction to Caffeine and Other Xanthines." In Textbook of Addiction Treatment. Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-36391-8_16.

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Favrod-Coune, Thierry, and Barbara Broers. "Addiction to Caffeine and Other Xanthines." In Textbook of Addiction Treatment: International Perspectives. Springer Milan, 2014. http://dx.doi.org/10.1007/978-88-470-5322-9_18.

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Persson, Carl G. A., Ingrid Erjefalt, and Birgitta Gustafsson. "Xanthines — Symptomatic or Prophylactic in Asthma?" In Directions for New Anti-Asthma Drugs. Birkhäuser Basel, 1988. http://dx.doi.org/10.1007/978-3-0348-9156-1_10.

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Streszczenia konferencji na temat "Xanthines"

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Mędza, Grzegorz, Jacek Wierzchowski, and David Shugar. "Fluorescent analogues of caffeine, theophylline, and other methyl-xanthines." In XIVth Symposium on Chemistry of Nucleic Acid Components. Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, 2008. http://dx.doi.org/10.1135/css200810478.

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Cazzola, Mario, Luigino Calzetta, Peter J. Barnes, et al. "Efficacy and safety profile of xanthines in COPD: a network meta-analysis." In ERS International Congress 2018 abstracts. European Respiratory Society, 2018. http://dx.doi.org/10.1183/13993003.congress-2018.pa615.

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Ding, Rui, Barton A. Kamen, Jia Shi, and Kathleen W. Scotto. "Abstract 992: Regulation of ABCG2 lysosomal degradation by xanthines: Role of the PI3K/AKT pathway." In Proceedings: AACR 104th Annual Meeting 2013; Apr 6-10, 2013; Washington, DC. American Association for Cancer Research, 2013. http://dx.doi.org/10.1158/1538-7445.am2013-992.

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Shatos, M., J. Doherty, D. Allen, and J. Hoak. "ALTERATIONS IN VASCULAR ENDOTHELIAL CELL FUNCTION BY OXYGEN-FREE RADICALS." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643365.

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The vascular endothelium is a target for oxidant-induced damage in many disease states including hyperoxia, inflammation, ischemia and reperfusion injury. However, little is known concerning oxidant injury to endothelial cells and its relationship to hemostasis. Our studies have focused on the ability of oxygen free radicals to injure and/or alter selected vascular endothelial cell functions pertinent to the regulation of hemostasis. Xanthine and xanthine oxidase, a well-characterized generating system for the production of the superoxide anion radical (O− 2) was used to sublethally injure hum
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Vanegas, D. C., C. Gomes, and E. S. McLamore. "Xanthine oxidase biosensor for monitoring meat spoilage." In SPIE Sensing Technology + Applications, edited by Brian M. Cullum and Eric S. McLamore. SPIE, 2014. http://dx.doi.org/10.1117/12.2050489.

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Royhoudhury, Sohini, Apoorva Shah, Ishaan Shah, Yogeswaran Umasankar, and Shekhar Bhansali. "Nano-Composite Enzymatic Xanthine Biosensor for Wound Diagnostics." In 2018 IEEE Sensors. IEEE, 2018. http://dx.doi.org/10.1109/icsens.2018.8589952.

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Tran, H., NN Le, AT Trinh, and TN Huynh. "Xanthine oxidase inhibitory activities of some Vietnamese medicinal plants." In 67th International Congress and Annual Meeting of the Society for Medicinal Plant and Natural Product Research (GA) in cooperation with the French Society of Pharmacognosy AFERP. © Georg Thieme Verlag KG, 2019. http://dx.doi.org/10.1055/s-0039-3400114.

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Matos, Maria João, Fernanda Borges, Lourdes Santana, et al. "Interest of 3-arylcoumarins as xanthine oxidase inhibitors." In The 19th International Electronic Conference on Synthetic Organic Chemistry. MDPI, 2015. http://dx.doi.org/10.3390/ecsoc-19-b002.

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Sari, Besse Illang, Hasnah Natsir, Seniwati Dali, et al. "Isolation, fractionation, and characterization of xanthine oxidase from goat’s milk." In THE 9TH INTERNATIONAL CONFERENCE OF THE INDONESIAN CHEMICAL SOCIETY ICICS 2021: Toward a Meaningful Society. AIP Publishing, 2022. http://dx.doi.org/10.1063/5.0104306.

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Ding, Rui, Jia Shi, and Kathleen W. Scotto. "Abstract 1746: Modulation of ABCG2 mediated multidrug resistance by xanthine derivatives." In Proceedings: AACR 102nd Annual Meeting 2011‐‐ Apr 2‐6, 2011; Orlando, FL. American Association for Cancer Research, 2011. http://dx.doi.org/10.1158/1538-7445.am2011-1746.

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Raporty organizacyjne na temat "Xanthines"

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Bedina, S. A., E. E. Mozgovaia, E. A. Tikhomirova, M. A. Mamus, S. S. Dotsenko, and A. S. Trofimenko. Xanthine oxidase and xanthine dehydrogenase activity in rheumatoid arthritis: the enzyme profile of blood plasma. ООО "ИМА-Пресс", 2018. http://dx.doi.org/10.18411/1995-4484-2018-56-33-8.

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Bedina, S. A., E. E. Mozgovaya, I. A. Zborovskaya, A. S. Trofimenko, and E. G. Korenskaya. ENZYMATIC PROFILE OF BLOOD PLASMA IN RHEUMATOID ARTHRITIS: ACTIVITY OF XANTHINE OXIDASE, XANTHINE DEHYDROGENASE AND SUPEROXIDE DISMUTASE. Планета, 2018. http://dx.doi.org/10.18411/978-5-907109-24-7-2018-xxxv-54-61.

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Bedina, S. A., E. E. Mozgovaya, A. S. Trofimenko, S. S. Spitsina, M. A. Mamus, and E. A. Tikhomirova. ENZYMATIC PROFILE OF BLOOD PLASMA IN SYSTEMIC SCLEROSIS: ACTIVITY OF XANTHINE OXIDASE, XANTHINE DEHYDROGENASE AND SUPEROXIDE DISMUTASE. "PLANET", 2019. http://dx.doi.org/10.18411/978-5-907192-54-6-2019-xxxvi-38-45.

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Bedina, S. A., E. E. Mozgovaya, A. S. Trofimenko, et al. XANTHINE OXIDASE, XANTHINE DEHYDROGENASE AND SUPEROXIDE DISMUTASE ACTIVITIES OF BLOOD PLASMA DEPENDING ON CLINICAL FEATURES OF SYSTEMIC SCLEROSIS. Academy of Natural Knowledge, 2019. http://dx.doi.org/10.18411/1996-3955-2019-10-268-272.

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Hodson, R. Analyzing Xanthine Dehydrogenase Iron-Sulfur Clusters Using Electron Paramagnetic Resonance Spectroscopy. Office of Scientific and Technical Information (OSTI), 2004. http://dx.doi.org/10.2172/826721.

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Mozgovaia, E. E., S. A. Bedina, A. S. Trofimenko, and I. A. Zborovskaia. Features of changes in the activity of xanthine oxidase and xanthine dehydrogenase in lymphocyte lysates and blood plasma in rheumatoid arthritis with the use of glucocorticoids. ООО ИМА-Пресс, 2018. http://dx.doi.org/10.18411/1995-4484-2018-56-3(2)-55-56.

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Bedina, S. A., E. E. Mozgovaia, A. S. Trofimenko, and I. A. Zborovskaia. The activity of enzymes of the xanthine oxidase / xanthine dehydrogenase complex in blood plasma and lymphocyte lysates in patients with seropositive and seronegative forms of rheumatoid arthritis. Академия Естествознания, 2018. http://dx.doi.org/10.18411/1996-3955-2018-6-61-64.

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Mozgovaya, E. E., S. A. Bedina, A. S. Trofimenko, M. A. Mamus, S. S. Spitsina, and I. A. Zborovskaya. XANTHINE OXIDOREDUCTASE ACTIVITY IN BLOOD DEPENDING ON THE FUNCTIONAL CLASS OF RHEUMATOID ARTHRITIS PATIENTS. DOI CODE, 2021. http://dx.doi.org/10.18411/wco-iof-esceo-2021-428-429.

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Mozgovaya, E. E., S. A. Bedina, I. A. Zborovskaya, et al. XANTHINE OXIDOREDUCTASE AND SUPEROXIDE DISMUTASE ACTIVITIES OF BLOOD PLASMA DEPENDING ON TYPE OF SYSTEMIC SCLEROSIS. "PLANET", 2019. http://dx.doi.org/10.18411/978-5-907192-54-6-2019-xxxvi-120-127.

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Scott, J. Robert. Characterization of the Iron-Sulfur Clusters in Xanthine Dehydrogenase Using Electron Paramagnetic Resonance Spectroscopy and Magnetic Coupling Interactions. Office of Scientific and Technical Information (OSTI), 2004. http://dx.doi.org/10.2172/826759.

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