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Artykuły w czasopismach na temat "ZnPcSO4"

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Bonegardt, Dmitry, Darya Klyamer, Aleksandr Sukhikh, Pavel Krasnov, Pavel Popovetskiy, and Tamara Basova. "Fluorination vs. Chlorination: Effect on the Sensor Response of Tetrasubstituted Zinc Phthalocyanine Films to Ammonia." Chemosensors 9, no. 6 (2021): 137. http://dx.doi.org/10.3390/chemosensors9060137.

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In this work, the effect of fluorine and chlorine substituents in tetrasubstituted zinc phthalocyanines, introduced into the non-peripheral (ZnPcR4-np, R = F, Cl) and peripheral (ZnPcR4-p, R = F, Cl) positions of macrocycle, on their structure and chemiresistive sensor response to low concentration of ammonia is studied. The structure and morphology of the zinc phthalocyanines films (ZnPcR4) were investigated by X-ray diffraction and atomic force microscopy methods. To understand different effects of chlorine and fluorine substituents, the strength and nature of the bonding of ammonia and ZnPc
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Guilherme, Vedovato Vilela de Salis¹ Fabíola Silva Garcia Praça² Margarete Moreno de Araújo2 Josimar O. Eloy² Wanessa Silva Garcia Medina*1. "LIPID-BASED NANOCARRIERS IMPROVED ZnPcSO4 CELLULAR UPTAKE IN HUMAN KERATINOCYTES FOR USE IN TOPICAL PHOTODYNAMIC THERAPY." Indian Journal of Medical Research and Pharmaceutical Sciences 4, no. 5 (2017): 28–37. https://doi.org/10.5281/zenodo.573572.

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Topical photodynamic therapy (PDT) involves both local administration of a photosensitizing drug followed by illumination or irradiation of visible light, resulting in light-drug combinations to kill cells and microorganisms. PDT using tetra-sulfonate phthalocyanine, a second generation of hydrophilic photosensitizers, has recently become a good treatment option for treatment of skin malignances. However, tetra-sulfonate phthalocyanine must be delivered into the target layers of the skin to achieve promising results. Thus, strategies to improve the phthalocyanine cell uptake based on lipid-bas
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Brozek-Pluska, Beata, Arkadiusz Jarota, Rafal Kania, and Halina Abramczyk. "Zinc Phthalocyanine Photochemistry by Raman Imaging, Fluorescence Spectroscopy and Femtosecond Spectroscopy in Normal and Cancerous Human Colon Tissues and Single Cells." Molecules 25, no. 11 (2020): 2688. http://dx.doi.org/10.3390/molecules25112688.

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Photodynamic therapy is a clinically approved alternative method for cancer treatment in which a combination of nontoxic drugs known as photosensitizers and oxygen is used. Despite intensive investigations and encouraging results, zinc phthalocyanines (ZnPcs) have not yet been approved as photosensitizers for clinical use. Label-free Raman imaging of nonfixed and unstained normal and cancerous colon human tissues and normal human CCD18-Co and cancerous CaCo-2 cell lines, without and after adding ZnPcS4 photosensitizer, was analyzed. The biochemical composition of normal and cancerous colon tis
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Mantareva, Vanya, Daniela Petrova, Latchezar Avramov, et al. "Long wavelength absorbing cationic Zn(II)-phthalocyanines as fluorescent contrast agents for B16 pigmented melanoma." Journal of Porphyrins and Phthalocyanines 09, no. 01 (2005): 47–53. http://dx.doi.org/10.1142/s1088424605000095.

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Three cationic zinc phthalocyanines ( ZnPcs ), tetrakis-(3-methylpyridyloxy)-, tetrakis-(3-hexyl-pyridyloxy)-, and tetrakis-(3-dodecylpyridyloxy)phthalocyaninezinc ( ZnPc Me, ZnPc He and ZnPc Do) have been studied as advanced fluorescent contrast agents for pigmented melanoma tumor. UV-vis spectroscopic properties of the monomers were investigated. Their photophysical behavior as a substantial part of dye-induced fluorescence was evaluated. The selective accumulation and labeling capacity towards B16F0 pigmented melanoma tumor were determined. Melanin containing cells were isolated and incubat
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Kussovski, Vesselin, Vanya Mantareva, Mahmut Durmuş, and Ivan Angelov. "Quaternized Zn(II) phthalocyanines for photodynamic strategy against resistant periodontal bacteria." Zeitschrift für Naturforschung C 73, no. 5-6 (2018): 221–28. http://dx.doi.org/10.1515/znc-2017-0167.

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AbstractPhotodynamic inactivation (PDI) has been featured as an effective strategy in the treatment of acute drug-resistant infections. The efficiency of PDI was evaluated against three periodontal pathogenic bacteria that were tested as drug-resistant strains. In vitro studies were performed with four water-soluble cationic Zn(II) phthalocyanines (ZnPc1–4) and irradiation of a specific light source (light-emitting diode, 665 nm) with three doses (15, 36 and 60 J/cm2). The well detectable fluorescence of ZnPcs allowed the cellular imaging, which suggested relatively high uptakes of ZnPcs into
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Santos, Andreia D., Diana Gonçalves, Rui C. Martins, et al. "Homogeneous Photosensitized Oxidation for Water Reuse in Cellars: A Study of Different Photosensitizers." Sustainability 15, no. 8 (2023): 6861. http://dx.doi.org/10.3390/su15086861.

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The demand for fresh water is increasing daily, requiring industries to take action to reduce the need for fresh water. Winemaking industries represent a massive hydric impact by combining the water consumed and the high volume of wastewater produced. The sun-driven photooxidation process has been widely employed in removing wastewater pollutants. This work employed four photosensitizers, Rose Bengal, AlPcS4, ZnPcS4, and TPP, for water reuse in cellars. A secondary effluent has been investigated as a water matrix. Of all the photosensitizers (PS) employed, ZnPcS4 showed better chemical oxygen
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Jiang, Zhou, Jiqing Ye, Jingyi Yang, Jian Wang, Lee Jia, and Rodney JY Ho. "Conjugation of Phthalocyanine Photosensitizer with Poly(amidoamine) Dendrimer: Improved Solubility, Disaggregation and Photoactivity Against HepG2 Cells." Current Cancer Drug Targets 19, no. 4 (2019): 312–20. http://dx.doi.org/10.2174/1568009618666180706164046.

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Objective: To improve solubility and to reduce aggregation, ZnPcC4 was conjugated to a third-generation poly-amidoamine dendrimer with amino end group (G3-PAMAM-NH2), which acts as a novel photodynamic therapy (PDT) drug carrier system. Methods: The phthalocyanines were synthesized by construction reaction. The nano drug was obtained from the conjugation of ZnPcC4 to G3-PAMAM-NH2, using EDC and NHS as coupling agents. The ZnPcC4@G3-PAMAM-NH2 conjugation was characterized by UV-Vis and MS. The 1O2 quantum yield of ZnPcC4@G3-PAMAM-NH2 in water was measured by the chemiluminescence method. The in
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Chota, Alexander, Blassan P. George, and Heidi Abrahamse. "In Vitro Cell Death Mechanisms Induced by Dicoma anomala Root Extract in Combination with ZnPcS4 Mediated-Photodynamic Therapy in A549 Lung Cancer Cells." Cells 11, no. 20 (2022): 3288. http://dx.doi.org/10.3390/cells11203288.

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Globally, lung cancer has remained the leading cause of morbidity and mortality in men and women. To enhance photodynamic therapeutic effects in vitro, the present study was designed to reduce dose-dependence in photodynamic therapy (PDT) and evaluate the anticancer effects of Dicoma anomala (D. anomala) root extracts (i.e., chloroform (Chl), ethyl acetate (EtOAc), and methanol (MeOH)) on A549 lung cancer cells. The most active extract of D. anomala (D.A) was used to establish the 50% inhibitory concentration (IC50), which was further used to evaluate the anticancer efficacy of D.A in combinat
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Huang, Yan, Guoxing Xu, Yiru Peng, Shaoqiang Chen, and Yunxia Wu. "Photodynamic Effects of ZnPcS4-BSA in Human Retinal Pigment Epithelium Cells." Journal of Ocular Pharmacology and Therapeutics 25, no. 3 (2009): 231–38. http://dx.doi.org/10.1089/jop.2008.0058.

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Nkune, Nkune Williams, and Heidi Abrahamse. "The Efficacy of Zinc Phthalocyanine Nanoconjugate on Melanoma Cells Grown as Three-Dimensional Multicellular Tumour Spheroids." Pharmaceutics 15, no. 9 (2023): 2264. http://dx.doi.org/10.3390/pharmaceutics15092264.

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Melanoma remains a major public health concern that is highly resistant to standard therapeutic approaches. Photodynamic therapy (PDT) is an underutilised cancer therapy with an increased potency and negligible side effects, and it is non-invasive compared to traditional treatment modalities. Three-dimensional multicellular tumour spheroids (MCTS) closely resemble in vivo avascular tumour features, allowing for the more efficient and precise screening of novel anticancer agents with various treatment combinations. In this study, we utilised A375 human melanoma spheroids to screen the phototoxi
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Rozprawy doktorskie na temat "ZnPcSO4"

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Souza, Joel Gonçalves de. "Avaliação da penetração cutânea iontoforética da zinco ftalocianina tetrassulfonada (ZnPcS4) e estudos de citotoxicidade em cultura de células tumorais." Universidade de São Paulo, 2011. http://www.teses.usp.br/teses/disponiveis/60/60137/tde-06072011-164252/.

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A Terapia Fotodinâmica (TFD) é uma modalidade terapêutica inovadora para o tratamento de tumores cutâneos. As ftalocianinas têm sido utilizadas como fotossensibilizantes sistêmicos devido à sua alta afinidade ao tecido tumoral e seu efeito acentuado quando irradiadas com luz. No entanto, a lipossolubilidade e o baixo coeficiente de partilha óleo/água dessas substâncias dificultam sua aplicação tópica, levando ao desenvolvimento de derivados carregados, como a zinco ftalocianina tetrassulfonada (ZnPcS4) na tentativa de aumentar sua solubilidade em água, bem como melhorar sua captação pelas célu
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Streszczenia konferencji na temat "ZnPcSO4"

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Medina, Wanessa, Clayton Azevedo, Patricia Farias, Beate Santos, Adriana Fontes, and Maria Vitoria Bentley. "Characterization of Topical Delivery System of ZnPcSO^4to Use in Photodynamic Therapy of Skin Cancer." In Latin America Optics and Photonics Conference. OSA, 2010. http://dx.doi.org/10.1364/laop.2010.mc3.

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Halkiotis, Konstantinos N., Dido M. Yova, and Gabriel E. Pantelias. "Photodynamic treatment of pancreatic cancer cells: genotoxicity and chromosome damage induced by red light and zinc tetrasulfonated phthalocyanines (ZnPcS4)." In BiOS Europe '98, edited by Benjamin Ehrenberg and Kristian Berg. SPIE, 1999. http://dx.doi.org/10.1117/12.339117.

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