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Teses / dissertações sobre o tema "0981"

Autor: Grafiati

Publicado: 25 de julho de 2024

Última modificação: 31 de julho de 2025

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1

Begum, Ghazala. "Epigenetic changes in the hypothalamus of offspring following maternal undernutrition." Thesis, University of Manchester, 2014. https://www.research.manchester.ac.uk/portal/en/theses/epigenetic-changes-in-the-hypothalamus-of-offspring-following-maternal-undernutrition(d2254013-0981-4038-b901-55f94601afc2).html.

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Epidemiological studies show that offspring subjected to maternal undernutrition during early pregnancy are prone to developing obesity and other diseases in adulthood. The hypothalamic energy regulating pathway may be altered in these offspring, with epigenetic changes as a core mechanism. Therefore, this thesis aimed to determine if epigenetic changes are present in this pathway in the hypothalami from offspring subjected to maternal undernutrition. The investigations are focused on the glucocorticoid receptor (GR) as an inhibitor of the anorexigenic neuropeptide pro-opiomelanocortin (POMC),

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2

SOUZA, Adriana Ferreira de. "Produção simultânea de bioemulsificante e lipídeos por Candida lipolytica UCP 0988 utilizando substratos agroindustriais." Universidade Federal de Pernambuco, 2016. https://repositorio.ufpe.br/handle/123456789/26034.

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Submitted by Pedro Barros (pedro.silvabarros@ufpe.br) on 2018-08-22T20:05:06Z No. of bitstreams: 2 license_rdf: 811 bytes, checksum: e39d27027a6cc9cb039ad269a5db8e34 (MD5) DISSERTAÇÃO Adriana Ferreira de Souza.pdf: 1586354 bytes, checksum: c17580ce2e26e119766228179c5b2459 (MD5)<br>Approved for entry into archive by Alice Araujo (alice.caraujo@ufpe.br) on 2018-08-29T21:35:29Z (GMT) No. of bitstreams: 2 license_rdf: 811 bytes, checksum: e39d27027a6cc9cb039ad269a5db8e34 (MD5) DISSERTAÇÃO Adriana Ferreira de Souza.pdf: 1586354 bytes, checksum: c17580ce2e26e119766228179c5b2459 (MD5)<br>Made availab

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3

Santana, Willma José de. "Produção de biossurfactante por Candida lipolytica (UPC 0988) utilizando óleo de pequi como fonte alternativa de Carbono." Universidade Federal de Pernambuco, 2012. https://repositorio.ufpe.br/handle/123456789/12754.

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Submitted by Amanda Silva (amanda.osilva2@ufpe.br) on 2015-04-08T14:55:03Z No. of bitstreams: 2 Tese completa 1.pdf: 1053273 bytes, checksum: 52d9d1ae7ecd2a53a7e5c5158a68dc0b (MD5) license_rdf: 1232 bytes, checksum: 66e71c371cc565284e70f40736c94386 (MD5)<br>Made available in DSpace on 2015-04-08T14:55:03Z (GMT). No. of bitstreams: 2 Tese completa 1.pdf: 1053273 bytes, checksum: 52d9d1ae7ecd2a53a7e5c5158a68dc0b (MD5) license_rdf: 1232 bytes, checksum: 66e71c371cc565284e70f40736c94386 (MD5) Previous issue date: 2012<br>CNPq<br>A produção de biossurfactantes tem sido amplamente investigada nos

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4

Andreas, Martin, Lorenz Kuessel, Stefan Wirth, et al. "Bioimpedance cardiography in pregnancy: A longitudinal cohort study on hemodynamic pattern and outcome." Springer Nature, 2016. http://dx.doi.org/10.1186/s12884-016-0918-8.

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Background: Pregnancy associated cardiovascular pathologies have a significant impact on outcome for mother and child. Bioimpedance cardiography may provide additional outcome-relevant information early in pregnancy and may also be used as a predictive instrument for pregnancy-associated diseases. Methods: We performed a prospective longitudinal cohort trial in an outpatient setting and included 242 pregnant women. Cardiac output and concomitant hemodynamic data were recorded from 11th-13th week of gestation every 5th week as well as at two occasions post partum employing bioimpedance car

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5

Rice, Linda J. "The biblical view of reactive attachment disorder." Santa Clarita, CA : The Master's College, 2006. http://dx.doi.org/10.2986/tren.091-0077.

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6

Coyle, Rachel Lynn. "Women and pornography, an examination of the problem and how to help them find freedom." Theological Research Exchange Network (TREN) Access this title online, 2006. http://dx.doi.org/10.2986/tren.091-0041.

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7

Rogers, Andrew D. "Calling sons to a life worth living a father and son study through Ecclesiastes." Theological Research Exchange Network (TREN), access this title online, 2006. http://dx.doi.org/10.2986/tren.091-0050.

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8

Bertelsen, Michelle. "A biblical perspective on euthanasia." Theological Research Exchange Network (TREN), access this title online, 2006. http://dx.doi.org/10.2986/tren.091-0053.

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9

Curran, Peggy E. "A biblical perspective on anorexia nervosa, workbook for teens and young adults." Theological Research Exchange Network (TREN), access this title online, 2006. http://dx.doi.org/10.2986/tren.091-0054.

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10

Isaacs, Victoria MacKenzie. "Preaching during the interim a transitional ministry lectionary centered on the table /." Denver, CO : Iliff School of Theology, 2008. http://dx.doi.org/10.2986/tren.098-0026.

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11

Davis, John Paul. "Performers of the faith an image for the church and a direction for homiletics /." Denver, CO : Iliff School of Theology, 2008. http://dx.doi.org/10.2986/tren.098-0025.

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12

Hahn, Zintack Albert. "Preaching on difficult passages in Mark's gospel based on performance criticism." Denver, CO : Iliff School of Theology, 2008. http://dx.doi.org/10.2986/tren.098-0022.

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13

Geslin, Daniel. "In search of a queer homiletic." Denver, CO : Iliff School of Theology, 2008. http://dx.doi.org/10.2986/tren.098-0027.

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14

Overley, Amy. "Overcoming abuse." Santa Clarita, CA : The Master's College, 2004. http://dx.doi.org/10.2986/tren.091-0031.

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15

Pollinger, Millicent M. "A woman's call to loving others through social graces." Santa Clarita, CA : The Master's College, 2006. http://dx.doi.org/10.2986/tren.091-0059.

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16

Mario, Erica Guilhen. "Ação do agonista não-peptídico da angiotensina-(1-7), AVE 0991, nas alterações metabólicas induzidas por suplementação com frutose." Universidade Federal de Minas Gerais, 2012. http://hdl.handle.net/1843/BUOS-96EHGK.

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Recent studies have shown that activation of angiotensin-(1-7) / receptor Mas axis plays important role in intermediary metabolism, evidenced by increase in insulin sensitivity. The compound AVE 0991 is a non-peptide angiotensin-1-7 agonist, which effects in intermediary metabolism has not yet been studied. Thus, the objective of this study was to evaluate the action of this agonist on the metabolic changes induced by fructose supplementation. Male Sprague-Dawley rats at 5 weeks of age were utilized. The animals were divided randomically into four groups: Group C: animals fed a commercial die

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17

Leite, Karla Carneiro de Siqueira. "Caracterização eletroquímica do composto LQFM-091, obtido por hibridação molecular a partir dos protótipos nimesulida e BF-389." Universidade Federal de Goiás, 2015. http://repositorio.bc.ufg.br/tede/handle/tede/5380.

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Submitted by Luciana Ferreira (lucgeral@gmail.com) on 2016-03-24T14:21:48Z No. of bitstreams: 2 Dissertação - Karla Carneiro de Siqueira Leite - 2015.pdf: 1941220 bytes, checksum: 6cab67f6a191dcb15c486db668a7233f (MD5) license_rdf: 23148 bytes, checksum: 9da0b6dfac957114c6a7714714b86306 (MD5)<br>Approved for entry into archive by Luciana Ferreira (lucgeral@gmail.com) on 2016-03-24T14:23:40Z (GMT) No. of bitstreams: 2 Dissertação - Karla Carneiro de Siqueira Leite - 2015.pdf: 1941220 bytes, checksum: 6cab67f6a191dcb15c486db668a7233f (MD5) license_rdf: 23148 bytes, checksum: 9da0b6dfac957114c6a7

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18

Blecha, Andreas. "Gentechnisches Design bakterieller Hüllproteine für die technische Nutzung." Doctoral thesis, Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden, 2005. http://nbn-resolving.de/urn:nbn:de:swb:14-1136195910253-09581.

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Als &quot;surface-layer&quot; (S-Layer, SL) bezeichnet man die regelmäßig strukturierten Hüllproteinlagen auf der Oberfläche von etwa 80 % aller bisher bekannten Bakterienspezies. Sie entstehen durch Selbstassemblierung von identischen Proteinuntereinheiten, die wiederum zumeist durch nichtkovalente Wechselwirkungen mit der darunterliegenden Zellwandkomponente verknüpft sind. Trotz ihrer Diversität auf der Ebene der Primärstruktur weisen S-Layer verschiedener Bakterienarten einheitliche physikochemische Merkmale auf. Dazu zählt u.a. die Wiedereinnahme einer hochgradig strukturierten, p

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19

Ballester, Riesco Benjamín. "Tecnología y vida social de los instrumentos líticos de los primeros cazadores, recolectores y pescadores costeros del semiárido. El caso de Punta Ñagué (LV-098A)." Tesis, Universidad de Chile, 2015. http://repositorio.uchile.cl/handle/2250/136510.

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20

Howald, Claudia. "Kinder mit Autismus im stationären Bereich." Bern Ed. Soziothek, 2005. http://www.soziothek.ch/?3-03796-098-1.

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21

Geremia, Alessandra. "The role of the IL23/IL17 pathway in inflammatory bowel disease." Thesis, University of Oxford, 2011. http://ora.ox.ac.uk/objects/uuid:f39c2ab5-098e-45d8-a800-e4c4bc7ae85f.

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The aetiology of IBD is unknown, but available evidence suggests that an aberrant immune response towards the commensal microbial flora is responsible for intestinal inflammation in genetically susceptible individuals. Studies from animal models of intestinal inflammation have greatly advanced our understanding of the immunological basis of IBD. However, translation of results from animal research into human studies is essential in order to improve treatment options and patient quality of life. In this thesis we present the successful introduction of translational studies on human tissue in ou

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22

Muehlemann, Anton. "Variational models in martensitic phase transformations with applications to steels." Thesis, University of Oxford, 2016. https://ora.ox.ac.uk/objects/uuid:bb7f4ff4-0911-4dad-bb23-ada904839d73.

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This thesis concerns the mathematical modelling of phase transformations with a special emphasis on martensitic phase transformations and their application to the modelling of steels. In Chapter 1, we develop a framework that determines the optimal transformation strain between any two Bravais lattices and use it to give a rigorous proof of a conjecture by E.C. Bain in 1924 on the optimality of the so-called Bain strain. In Chapter 2, we review the Ball-James model and related concepts. We present some simplification of existing results. In Chapter 3, we pose a conjecture for the explicit form

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23

England, Katherine Sara. "A potent and selective inhibitor of a histone demethylase." Thesis, University of Oxford, 2015. https://ora.ox.ac.uk/objects/uuid:e078e629-0987-449b-96dc-748601f2cff3.

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Post-translational modifications (PTMs) to histone proteins play important roles in the regulation of gene expression. Histone lysine demethylases (KDMs) remove methyl groups from N?-amino methylated lysine residues. There are two classes of human KDMs; the flavin adenosine dinucleotide-dependent demethylases (the KDM1 subfamily) and the 2-oxoglutarate- (2OG) dependent Jumonji C (JmjC) demethylases (KDM2-7). Misregulation and mutation of histone demethylases are associated with multiple human diseases including cancer. Hence potent and selective inhibitors are of interest for investigations in

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24

Liu, Yang. "Privacy-preserving targeted advertising for mobile devices." Thesis, University of Oxford, 2017. http://ora.ox.ac.uk/objects/uuid:c2c929cc-0931-457a-afff-d973624a356c.

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With the continued proliferation of mobile devices, the collection of information associated with such devices and their users - such as location, installed applications and cookies associated with built-in browsers - has become increasingly straightforward. By analysing such information, organisations are often able to deliver more relevant and better focused advertisements. Although such Targeted Mobile Advertising (TMA) offers great benefits to advertisers, it gives rise to a number of concerns, with privacy-related concerns being prominent amongst them. It follows that there is a need for

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25

Pullen, Anne Jennifer. "Behavioural indicators of candidate enrichments for kennel housed dogs." Thesis, University of Bristol, 2011. http://hdl.handle.net/1983/add992d2-09f1-4658-aedf-93198b620b3d.

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The welfare of kennelled dogs is often considered to be suboptimal and therefore to require "enrichment". This thesis examines the short-term reactions of dogs to a variety of potential enrichments. Where possible, comparisons were also made between two contrasting kennel environments, to indicate to what degree interest in enrichments is influenced by environment, as well as fulfilling species requirements. Interaction with toys was investigated as an example of inanimate enrichment. Toys that made a noise and/or could be chewed easily were found to be preferred to more robust toys, suggestin

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26

Shu, Chi-Kou. "Computing exact approximations of a Chaitin omega number." Thesis, University of Auckland, 2004. http://hdl.handle.net/2292/38.

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A Chaitin Omega number, Ω, is the halting probability of a universal Chaitin (self-delimiting Turing) machine. Every Ω number is both computably enumerable and random. In particular, every Ω number is non-computable. In this thesis, we describe a method to compute the exact values of the first 64 successive bits of a natural Chaitin Omega number. We first describe a model of computation which has been defined and proved to be a universal Chaitin machine U. We then propose a method (procedure) which combines iterative executions of an algorithm with mathematical analysis to get the exact v

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27

Siliņš, Ilvars. "Molecular epidemiology of human papillomavirus and cervical cancer /." Stockholm : [Karolinska institutets bibl.], 2001. http://diss.kib.ki.se/2001/91-7349-091-1/.

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28

Duan, Jianxin. "Protein folding, stability and recognition /." Stockholm, 2004. http://diss.kib.ki.se/2004/91-7140-098-2/.

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29

Hermansson, Liselotte. "Upper limb reduction deficiencies in Swedish children : classification, prevalence and function with myoelectric prostheses /." Stockholm, 2004. http://diss.kib.ki.se/2004/91-7140-091-5/.

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30

Stubbs, Estelle Vivien. "A study of the codicology of four early manuscripts of the Canterbury Tales." Thesis, University of Sheffield, 2006. http://etheses.whiterose.ac.uk/15177/.

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This thesis is a study of the physical features of the four earliest manuscripts of the Canterbury Tales all dated to the first years after the death of Geoffrey Chaucer. I assess the ways in which codicological examination can contribute to the understanding of a complex textual tradition and inform the study of the text. The thesis is divided into two volumes. The first volume contains the seven chapters which make up the thesis. The first chapter contains a review of the printed editions of the poem since Caxton's first edition of 1476 and a summary of the most important contributions of sc

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31

Himsworth, Katherine. "The Peniarth MS 22 Brut y Brenhinedd and continuation chronicle, and its 15th century Aberystwyth scribe, Dafydd ap Maredudd Glais." Thesis, Aberystwyth University, 2015. http://hdl.handle.net/2160/5dcc8e8b-3f1d-4a4d-9713-d9ed9c7288f1.

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The Peniarth 22 manuscript is, except for the last four pages, a fifteenth-century copy of Brut y Brenhinedd, the Welsh translation of Geoffrey of Monmouth's Historia Regum Britanniae; it was penned in 1444 by one Dafydd ap Maredudd Glais. It belongs to the Dingestow family of manuscripts, which in turn is related, in part, to the Llanstephan Version and Liber Coronacionis Britanorum manuscripts, although the detail of this relationship - and that of the Dingestow manuscripts to one another - still begs a number of questions. Peniarth 22 itself is very similar to, though not a copy of, the ear

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32

Wang, Jianlan. "Silk facing of ancient Chinese manuscripts." Thesis, Queen's University Belfast, 2014. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.675481.

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The thesis has profiled silk facing treatments to manuscripts in the Stein Collection in the British Library, via its unique historical background, compared with the lamination technique that was prevalent in conservation in the last century in libraries and archives. The correction of the previous inappropriate preservation methods might have not aroused enough attentiveness, or critical attention, in the conservation arena. IR and Raman spectroscopy were widely applied in this project, for the characterisation of the different silks removed from the manuscripts, in comparison with new silk f

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33

Beattie, Luke Timothy. "How were the anonymous Castle Ashby play manuscripts created, and why?" Thesis, University of Exeter, 2011. http://hdl.handle.net/10036/3478.

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In 1977, a long-lost collection of manuscripts of plays, poems, and non-fiction texts from the 17th century was re-discovered in the library of Castle Ashby, Northamptonshire. Most of the items are not signed by an author, and have no known record of publication or performance. These technically anonymous items have received minimal scholarly attention in the three-plus decades since their recovery, and what comment there has been has not entirely agreed upon the collection's authorship, purpose, or even era of composition. This thesis takes a confident position on those debates by investigati

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34

White, Thomas. "Potential lives : the matter of late medieval manuscripts." Thesis, Birkbeck (University of London), 2016. http://bbktheses.da.ulcc.ac.uk/222/.

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Late medieval vernacular literary texts frequently reflect on their physical existence; they establish a poetics of material composition that is productively ambivalent about the contingencies of literary making in a manuscript culture. This thesis traces the ‘potential life’ of a late medieval manuscript. Four keywords (blankness, palimpsests, textiles, and fragments) provide the impetus for a discussion that connects a wide range of literary, codicological, and theoretical materials, in a mode that is iterative and additive. Manuscripts are not simply containers or substrates for literary te

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35

Buggins, Rosemary Elisabeth. "The Coventry pontifical and liturgical transmission patters in the twelth and thirteenth centuries." Thesis, University of Bristol, 2015. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.682347.

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The focal point of this thesis is my complete transcription of the thirteenth-century Coventry Pontifical manuscript (Cambridge, University Library, Ff. VI. 9). In order to contextualise the Coventry Pontifical manuscript, this thesis comprises two investigative strands. The first is an exploration of the significance of the manuscript in the lives of its medieval users; the interactions between the manuscript and its culture; and the interplay between the manuscript and its users. To further our understanding of the significance of the Coventry Pontifical to its users, this thesis surveys the

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36

Hirschfeld, Marin. "Intimacy in contemporary digital cinema." Thesis, University of Oxford, 2012. http://ora.ox.ac.uk/objects/uuid:8e212865-09d1-4bf7-bf05-76806a2e1e21.

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Critical discourses on contemporary digital cinema tend to be either overtly negative, framed within a rhetoric of loss or disenfranchisement, or unilaterally positive, celebrating the user agency and freedom digital technologies enable. Both these conceptual positions are unhelpful because they either focus on what contemporary digital cinema fails to do or what it should do, without examining more closely how it actually functions. What is needed is a third, neutral approach which takes both sides into consideration but is also aware of their limitations and weaknesses. This thesis takes as

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37

Swenson, Sarah A. "A gene's eye vew : W.D. Hamilton, the science of society, and the new biology of enlightened self-interest, 1950-1990." Thesis, University of Oxford, 2015. http://ora.ox.ac.uk/objects/uuid:4c979713-0911-4cc0-9a7f-05fb0455f128.

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W.D. Hamilton has been celebrated as the twentieth-century Darwin. His extension of evolutionary theory to explain social behaviours has been extensively documented. Current accounts, however, have often overlooked the extent to which his early research goals were tied to his desire to see that a better world was created through a scientific understanding of society. In fact, when his interests in humans, and especially his eugenic concerns, have been acknowledged, they have been distanced from his scientific achievements and treated separately. Using new sources to reexamine the development o

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Florence, Margaret Mary. "Migration Stimulating Factor : the search for inhibitors." Thesis, University of Dundee, 2013. https://discovery.dundee.ac.uk/en/studentTheses/20738022-0982-4ec5-ade3-3cdf8e5beed3.

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The oncofetal protein Migration Stimulating Factor (MSF) is a truncated isoform of human fibronectin which exhibits numerous bioactivities that are pertinent to cancer progression. The MSF protein (70kDa) has potent motogenic activity, with only femtomolar concentrations required to produce half-maximal. The proteolytic degradation of MSF generates the functionally equivalent 43kDa Gel-BD domain and 21kDa IGD peptide. The screening of conditioned medium (CM) for bioactivity revealed two sources of MSF-inhibitory (MSF-I) activity; the spontaneously immortalised human keratinocyte cell line (HaC

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39

Lee, Elaine Carole. "Disclosure in maternity care contexts : the paradigm case of sexual orientation." Thesis, University of Dundee, 2010. https://discovery.dundee.ac.uk/en/studentTheses/f6167a54-09d1-4e3e-a31d-e2108dca9fce.

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This thesis is a hermeneutic phenomenological study of the concept of disclosure in maternity care contexts using the example of sexual orientation. There is a significant body of literature within psychology and sociology relating to the health and social purposes and consequences of disclosure. There is a further body of outcomes-focused evidence relating to disclosure of sexual orientation in health care. There is, however, little research undertaken into the disclosure of sexual orientation in pregnancy as an action with motive and purpose. This study aimed to address this issue. The study

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40

Ankit, Bajpai. "SQL versus MongoDB from an application development point of view." Kansas State University, 2014. http://hdl.handle.net/2097/18816.

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Master of Science<br>Department of Computing and Information Sciences<br>Doina Caragea<br>There are many formats in which digital information is stored in order to share and re-use it by different applications. The web can hardly be called old and already there is huge research going on to come up with better formats and strategies to share information. Ten years ago formats such as XML, CSV were the primary data interchange formats. And these formats were huge improvements over SGML (Standard Generalized Markup Language). It’s no secret that in last few years there has been a huge transformat

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41

Vidiyala, Akhila. "Android application of Throck mobile." Kansas State University, 2013. http://hdl.handle.net/2097/15318.

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Master of Science<br>Department of Computing and Information Sciences<br>Daniel Andresen<br>The aim of this project is to develop an android application for managing and organizing activities of various departments in ThrockMorton building at K-State. Mobile application development is a growing trend in computer industry. With the advancements in mobile technologies and efficient 3G and 4G wireless communications, a number of desktop applications are now becoming available as mobile applications. Android has the leading market share in the entire smart phone OS available. It gives lot of space

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42

Sanderson, Robert. "Linking past and future : an application of dynamic HTML for medieval manuscript editions." Thesis, University of Liverpool, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.288863.

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43

McCrae, James. "Sketch-based Path Design." Thesis, 2008. http://hdl.handle.net/1807/11154.

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We first present a novel approach to sketching 2D curves with minimally varying curvature as piecewise clothoids. A stable and efficient algorithm fits a sketched piecewise linear curve using a number of clothoid segments with G2 continuity based on a specified error tolerance. We then present a system for conceptually sketching 3D layouts for road and other path networks. Our system makes four key contributions. First, we generate paths with piecewise linear curvature by fitting 2D clothoid curves to strokes sketched on a terrain. Second, the height of paths above the terrain is automatically

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44

Benabbas, Siavosh. "On Hierarchies of Strong SDP Relaxations for Combinatorial Optimization Problems." Thesis, 2012. http://hdl.handle.net/1807/33933.

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Studying the approximation threshold of NP-hard optimization problems, i.e. the ratio of the objective value achievable by a polynomial time algorithm to that of the optimal solution is an important field in theoretical computer science. In the past two decades there has been significant development both in terms of finding good approximation algorithms, e.g. through the use of semidefinite programming and hardness of approximation, e.g. the development of Probabilistically Checkable Proofs and Unique Games Conjecture. Trying to prove lower bounds for the approximation threshold of an optimiza

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Trommelen, Michelle Suzanne. "Quaternary stratigraphy and glacial history of the Fort Nelson (southeast) and Fontas River (southwest) map areas (NTS 094J/SE and 0941/SW), northeastern British Columbia." Thesis, 2006. http://hdl.handle.net/1828/2009.

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The study area in northeast British Columbia extends from the Rocky Mountains in the west to the Fort Nelson Lowland in the east, and includes the westernmost extend of the Laurentide Ice Sheet (LIS) and the easternmost extend of the Cordilleran Ice Sheet (CIS) in the Late Pleistocene. Surficial mapping conducted over portions of the Fontas and Fort Nelson map areas (NTS 094I/SW and 094J/SE, respectively) provides information on sediment distribution and characteristics as well as glacial history. This information has direct implications for geotechnical investigations, aggregate resources and

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Meeds, Edward. "Nonparametric Bayesian Methods for Extracting Structure from Data." Thesis, 2008. http://hdl.handle.net/1807/11235.

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One desirable property of machine learning algorithms is the ability to balance the number of parameters in a model in accordance with the amount of available data. Incorporating nonparametric Bayesian priors into models is one approach of automatically adjusting model capacity to the amount of available data: with small datasets, models are less complex (require storing fewer parameters in memory), whereas with larger datasets, models are implicitly more complex (require storing more parameters in memory). Thus, nonparametric Bayesian priors satisfy frequentist intuitions abou

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Medvedev, Paul. "Genome Graphs." Thesis, 2010. http://hdl.handle.net/1807/26297.

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Whole-genome shotgun sequencing is an experimental technique used for obtaining information about a genome’s sequence, whereby it is broken up into many short (possibly overlapping) segments whose sequence is then determined. A long-standing use of sequencing is in genome assembly – the problem of determining the sequence of an unknown genome, which plays a central role for the sequencing of novel species. However, even within the same species, the genomes of two individuals differ, and though these variations are relatively small, they account for the observed variation in phenotypes. A large

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Kvasov, Stanislav. "DREM: Architectural Support for Deterministic Redundant Execution of Multithreaded Programs." Thesis, 2009. http://hdl.handle.net/1807/18795.

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Recently there have been several proposals to use redundant execution of diverse replicas to defend against attempts to exploit memory corruption vulnerabilities. However, redundant execution relies on the premise that the replicas behave deterministically, so that if inputs are replicated to both replicas, any divergences in their outputs can only be the result of an attack. Unfortunately, this assumption does not hold for multithreaded programs, which are becoming increasingly prevalent -- the non-deterministic interleaving of threads can also cause divergences in the replicas. This the

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Daniella, Perri. "The Role of Intravenous Immunoglobulin Anti-A and Anti-B in Complement Activation and Red Blood Cell Phagocytosis." Thesis, 2009. http://hdl.handle.net/1807/18976.

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Intravenous immunoglobulin is a human blood derived product that is used to treat immunodeficiencies and autoimmune disorders. An adverse side effect of IVIg therapy is hemolysis. Patients who experience hemolysis are mainly blood group A or AB. Clinical laboratory studies have demonstrated that IVIg contains ABO blood group antibodies, which can bind complement proteins. This study hypothesizes that anti-A/B in IVIg will bind to A/B antigens and activate complement in a dose dependant manner, which may lead to enhanced RBC phagocytosis. This study observed that the quantity of ABO antigens do

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Filmus, Yuval. "Spectral Methods in Extremal Combinatorics." Thesis, 2013. http://hdl.handle.net/1807/43555.

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Extremal combinatorics studies how large a collection of objects can be if it satisfies a given set of restrictions. Inspired by a classical theorem due to Erdos, Ko and Rado, Simonovits and Sos posed the following problem: determine how large a collection of graphs on the vertex set {1,...,n} can be, if the intersection of any two of them contains a triangle. They conjectured that the largest possible collection, containing 1/8 of all graphs, consists of all graphs containing a fixed triangle (a triangle-star). The first major contribution of this thesis is a confirmation of this conjecture.

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