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Teses / dissertações sobre o tema "Animal mechanics"

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1

Robles, Alexandro Heiblum. "Statistical mechanics of animal territoriality." Thesis, University of Bristol, 2016. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.707747.

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2

Taylor, Graham K. "Animal flight dynamics : mechanics of stability and control." Thesis, University of Oxford, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.270179.

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3

Fust, Anita. "Lung mechanics in mice : effect of decorin deficiency." Thesis, McGill University, 2003. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=80268.

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Decorin is required for the normal fibrillogenesis and spatial arrangement of collagen. As collagen is important in determining the elastic behaviour of the lung, we hypothesized that lung tissue mechanics would be altered in decorin deficient (Dcn-/-) mice. Complex impedance, pressure-volume curves, and length-stress curves of lung parenchyma were measured in C57BL/6 mice, 6 Dcn-/- and 6 wildtype ( Dcn+/+), both in vivo and in vitro. Immunohistochemistry and Western blotting were performed to identify decorin and biglycan in the lung tissues. In vivo, airway resistance was decreased an
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4

Nauen, Jennifer Claire. "Biomechanics of two aquatic defense systems : 1. The scaling of tail-flip kinematics and force production by the California spiny lobster Panulirus interruptus : 2. Shear sensitivity and interspecific variation in flow-stimulated dinoflagellate bioluminescence /." Diss., Connect to a 24 p. preview or request complete full text in PDF format. Access restricted to UC campuses, 1998. http://wwwlib.umi.com/cr/ucsd/fullcit?p9823710.

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5

Ferreira, Matos Gomes Rute. "Respiratory mechanics in small animals : influence of size and age." Thesis, McGill University, 2001. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=38188.

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Although rodents have been widely used in respiratory research, there are still only limited data comparing respiratory mechanics between different species of small animal. In order to provide further insight into the mechanical behavior of the respiratory systems of different sized small animals, accurate measurements of respiratory impedance (Zrs) were made in four different rodent species and in the developing rat over a broad range of frequencies at various levels of positive end-expiratory pressure (PEEP). PEEP dependencies of airway and tissue properties were interpreted in terms of phys
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6

Johnston, Sharon J. "Respitatory mechanics in stutterers' speech." Thesis, McGill University, 1996. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=40369.

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This thesis contains four manuscripts examining the respiratory mechanics of normal and stuttering speech. The first study (J.Appl.Physiol. 75 (2):696-703, 1993) examined lung volume (V scL) during stutterers' relatively fluent speech. We showed that stutterers used the V scL extremes. This suggested that stutterers recruited their respiratory muscles in a different manner than normals to maintain subglottic pressure (Psg). We therefore investigated respiratory muscle recruitment patterns in normals and stutterers. In the second study, (submitted to J.A.P.), we modified the Campbell pressure v
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7

Burke, Susan P. (Susan Patricia). "Dyspnea and the mechanics of breathing during progressive exercise." Thesis, McGill University, 1993. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=57002.

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This study investigates dyspnea and the mechanics of breathing during progressive exercise. Three subject groups, athletes, normal sedentary subjects and chronic obstructive diseased patients were studied during progressive exercise testing to exhaustion on a cycle ergometer. Subjects rated dyspnea on a Borg Scale. Inspiratory flow, esophageal/gastric pressures and rib cage/abdominal displacements were measured.<br>Subjects demonstrated two patterns of dyspnea response to changes in esophageal (pleural) pressure. All athletes, two normals and five patients were termed "low dyspnea responders",
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8

Dechman, Gail Sterns. "The effect of lung volume below normal functional residual capacity on respiratory system mechanics." Thesis, McGill University, 1993. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=41568.

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This thesis examines changes in the mechanical behaviour of the canine and human respiratory systems to changes in lung volume below normal functional residual capacity (FRC). In open chested dogs lung elastance (E$ sb{ rm L}$) increased and lung resistance (R$ sb{ rm L}$) changed little with decreases in positive end-expiratory pressure (PEEP) of the ventilatory circuit. The dominance of plastoelastic lung tissue properties at low lung volumes was used to interpret the lack of change in R$ sb{ rm L}$. Computed tomography demonstrated that pleural effusion (PE) created atelectasis in dependent
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9

Sergio, Lauren E. (Lauren Elisabeth). "The kinematic organization of the wipe relfex in the spinal frog /." Thesis, McGill University, 1990. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=59638.

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The kinematics of wiping movements to the back were examined in spinal adult Rana Catesbeiana. The aim was to identify the elements of the back wipe and their functional role. The data show that there are three essential phases of the wiping movement: a placing phase; a flexion of the hip and knee; and a whisk/extension phase. The first phase is the only one which is dependent upon stimulus location. The spinal frog adjusts the hindlimb to account for stimulus location in the rostro-caudal direction. There is no adjustment for stimulus position along the medial-lateral axis of the body. It is
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10

Paskins, Keith Edward. "The mechanics and energy economy of animal jumping and landing applied to autonomous robots." Thesis, University of Bath, 2007. https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.760869.

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Irregular terrain is difficult for small robots to traverse, so the research in this thesis endeavours to develop a jumping robot as a solution to this problem. Gliding is proposed as a means of reducing the landing impact forces, and potentially extending the range of each jump. The biomechanics of jumping and gliding are introduced from fundamental principles, before various examples from nature are described and contrasted. Flying squirrels glide quickly between trees by stretching out their patagia, membranous skin folds spreading between the wrists and ankles. Several hypotheses exist to
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11

Hackmann, Alexander. "Contamination and biomechanics of cleaning structures in insects." Thesis, University of Cambridge, 2015. https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.709213.

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12

Angle, Thomas Craig Weimar Wendi Hannah. "An evaluation of the effects of two natural surfaces on the kinematics of the canine sprint start." Auburn, Ala, 2009. http://hdl.handle.net/10415/1674.

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13

Moll, Karin. "Biomechanics of the foraging behavior in leaf-cutting ants." Thesis, University of Cambridge, 2012. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.610342.

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14

Farrell, Bradley J. "Dynamic stability of quadrupedal locomotion: animal model, cortical control and prosthetic gait." Diss., Georgia Institute of Technology, 2012. http://hdl.handle.net/1853/45951.

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The ability to control balance and stability are essential to prevent falls during locomotion. Maintenance of stable locomotion is challenging especially when complicated by amputation and prosthesis use. Humans employ several motor strategies to maintain stability during walking on complex terrain: decreasing walking speed, adjusting stride length and stance width, lowering the center of mass, and prolonging the double support time. The mechanisms of selecting these motor strategies by the primary motor cortex are unknown and cannot be studied directly in humans. There is also little informat
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15

Stahl, Victoria Ann. "A biomechanical analysis of the role of the crural fascia in the cat hindlimb." Diss., Georgia Institute of Technology, 2010. http://hdl.handle.net/1853/34701.

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The potential of the crural fascia to increase the articulation of the posterior thigh muscles through the in series connection of the structures, suggests that the crural fascia may influence the endpoint force direction of the muscles by partially redirecting the muscular force output. Furthermore, not only the in series connections should be considered but also how the parallel alignment of the crural fascia and the triceps surae may influence the force direction from the muscles. A redirection in force may, in turn, affect the intra-limb coordination or contribute to the selection of a t
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16

Simoni, Mario F. "Synthesis and analysis of a physical model of biological rhythmic motor control with sensorimotor feedback." Diss., Georgia Institute of Technology, 2002. http://hdl.handle.net/1853/13284.

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17

Tufekci, Pelin Melisa. "Development of a novel experimental model to investigate the influence of mechanics on bone healing." Thesis, Queensland University of Technology, 2015. https://eprints.qut.edu.au/90730/1/Pelin_Tufekci_Thesis.pdf.

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This dissertation proposed a novel experimental model combining a defect configuration with an active instrumented fixation device to investigate the influence of mechanics on bone healing. The proposed defect configuration aimed to minimise physiological loading within an experimental fracture gap and the instrumented fixator was used for the application of controlled displacements and in vivo stiffness monitoring of the healing process. This thesis has provided a novel approach to advance current knowledge and understanding of mechanobiology, which has been limited in previous experimental m
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18

Korecki, Casey. "Effects of Compression Loading, Injury, and Age on Intervertebral Disc Mechanics, Biology and Metabolism Using Large Animal Organ and Cell Culture Systems." ScholarWorks @ UVM, 2008. http://scholarworks.uvm.edu/graddis/126.

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The intervertebral disc (IVD) is a complex orthopaedic tissue that is located between the vertebrae in the spine. Degeneration of the IVD is thought to be a contributor to low back pain (LBP), which affects up to 80% of the population at enormous economic cost. The role of the intervertebral disc in supporting and resisting applied loading to the spine, along with the observation of disorders associated with abnormal spinal loading, provide support to the theory that applied mechanical loading is crucial in maintaining the health of the intervertebral disc. The encompassing goal of this
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19

Jones, Christopher David Stanford. "On the cross-sectional form of the patella in several primates." Title page, table of contents and abstract only, 2003. http://web4.library.adelaide.edu.au/theses/09PH/09phj764.pdf.

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20

Perchiazzi, Gaetano. "Artificial Neural Networks (ANN) in the Assessment of Respiratory Mechanics." Doctoral thesis, Uppsala : Acta Universitatis Upsaliensis : Univ.-bibl. [distributör], 2004. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-4665.

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21

Cheng, Bo. "Passive rotational damping in flapping flight." Access to citation, abstract and download form provided by ProQuest Information and Learning Company; downloadable PDF file, 89 p, 2009. http://proquest.umi.com/pqdweb?did=1889090361&sid=9&Fmt=2&clientId=8331&RQT=309&VName=PQD.

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22

Akkoul, Smaïl. "Filtrage et déconvolution en imagerie de bioluminescence chez le petit animal." Phd thesis, Université d'Orléans, 2010. http://tel.archives-ouvertes.fr/tel-00585392.

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Cette thèse est consacrée au traitement d'images de bioluminescence chez le petit animal. Ce type d'imagerie, bien qu'utilisé en routine pour la recherche en cancérologie par exemple, présente néanmoins des problèmes liés aux phénomènes de diffusion et d'absorption par les tissus internes à l'animal. Il s'ajoute à cela le bruit du système d'acquisition ainsi que le bruit lié aux rayonnements cosmiques. Ceci influe sur la qualité des images acquises et rend leur exploitation délicate. Le but de cette thèse est de compenser ces effets perturbateurs. Les travaux menés ont abouti à la proposition
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23

Horner, Angela M. "Crouched Locomotion in Small Mammals: The Effects of Habitat and Aging." Ohio University / OhioLINK, 2010. http://rave.ohiolink.edu/etdc/view?acc_num=ohiou1283529573.

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24

Field, Evelyn F., and University of Lethbridge Faculty of Arts and Science. "Sex differences in movement organization II : the organization of sex differences in movement during food protection, contact righting, skilled reaching and vertical exploration in the rat : the role of gonadal steroids, body morphology, and the central nervous system." Thesis, Lethbridge, Alta. : University of Lethbridge, Faculty of Arts and Science, 2006, 2006. http://hdl.handle.net/10133/14.

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Whether there are sex differences in the kinematic organization of non-reproductive behaviors is rarely addressed. In this thesis, evidence is presented that male and female rats organize their posture and stepping differently during a food protection task, contact righting, skilled reaching, and vertical rearing. Neonatal gonadal steroid exposure can alter sex-typical patterns of movement organization. Whether these differences are due to sex differences in body morphology or central nervous system (CNS) was also addressed using gravid females and tfm males. The results reveal that sex di
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25

Anciães, Adriana Martins. "Análise temporal de mecânica respiratória e morfometria pulmonar em camundongos após instilação nasal de papaína." Universidade de São Paulo, 2011. http://www.teses.usp.br/teses/disponiveis/5/5160/tde-02082011-165559/.

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Objetivos: Verificar alterações na mecânica e parâmetros de morfometria pulmonar em um estudo temporal sobre enfisema em um modelo animal. Métodos:Setenta camundongos Balb / c receberam instilação nasal de solução de papaína ou salina e foram estudados no 1º, 3º, 15º, 28º e 40º dias após a instilação. Resistência das vias aéreas (Raw), Resistência do tecido (Gtis) e elastância tecidual (Htis), foram analisados. Intercepto Linear Médio (Lm), a proporção do volume de fibras elásticas e colágenas, macrófagos (MAC), o número de células que expressam MMP12 e a expressão de -isoprostano 8 no parênqu
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26

Aoki, Fabio Gava. "Modelos matemáticos aplicados na avaliação da mecânica respiratória em camundongos com desafios de agonista da musculatura lisa." Universidade de São Paulo, 2013. http://www.teses.usp.br/teses/disponiveis/3/3142/tde-01082013-153108/.

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Modelos matemáticos são utilizados como ferramentas na avaliação da mecânica respiratória para a compreensão da fisiologia e patologias do sistema respiratório. A presente pesquisa visou avaliar, através da aplicação de modelos matemáticos, a mecânica respiratória em camundongos submetidos à metacolina. Deu-se ênfase no modelo linear de compartimento único e suas variantes não lineares. Camundongos C57BL/6 (n = 8) foram traqueostomizados, ventilados mecanicamente (flexiVent, SCIREQ, Canadá) e perturbações em volume foram aplicadas para a modelagem do sistema respiratório. O protocolo experimen
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27

Flaherty, Elizabeth A. "Using energetics and diet to predict the movements of northern flying squirrels (Glaucomys sabrinus) in the managed forests of southeast Alaska." Laramie, Wyo. : University of Wyoming, 2008. http://proquest.umi.com/pqdweb?did=1799828911&sid=1&Fmt=2&clientId=18949&RQT=309&VName=PQD.

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28

Robertson, Galen Charles. "Quantification of Skeletal Phenotype Using Micro-CT and Mechanical Testing." Thesis, Georgia Institute of Technology, 2004. http://hdl.handle.net/1853/4874.

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With the vast array of genetically altered (knockout) mice becoming available there is a need for quantitative, repeatable, and efficient methodologies to characterize the phenotypic consequences of knocking out specific genes. Since knockout animals often have the ability to compensate for a single missing gene, it is important to examine the structural, material and morphological properties to obtain a thorough understanding of the changes occurring. For this project, femurs of knockout mice were first scanned using microcomputed tomography (micro-CT) to obtain high-resolution images of th
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29

Maksym, Geoffrey N. "Modelling lung tissue theology." Thesis, McGill University, 1997. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=42087.

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A model was developed to account for the static elastic behaviour of the lung tissue strip in terms of distributions of collagen and elastin fibers. Distributions of collagen fiber lengths and elastin fiber stiffnesses were determined by fitting the model to data from dog lung tissue strips. These distributions followed 1/f power-laws for more than 95% of the data. Computer simulations of two dimensional tissue strip models with 1/f distributions of collagen fiber lengths also predicted realistic stress-strain curves. The simulations illustrated the gradual development of geometric and stress
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30

Ramananarivo, Sophie. "Propulsion biomimétique de structures élastiques." Phd thesis, Université Paris-Diderot - Paris VII, 2014. http://pastel.archives-ouvertes.fr/pastel-00955323.

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Les oiseaux et poissons se déplacent dans leur environnement fluide en interagissant avec l'air/eau qui les entoure. Pour des régimes inertiels, les mécanismes de propulsion se basent sur un transfert de quantité de mouvement au fluide; les battements d'ailes ou de nageoires générant un jet dans le sillage de l'animal qui le propulse vers l'avant. Pour les oiseaux comme pour les poissons, les structures utilisées possèdent une certaine flexibilité, et sont donc susceptibles de plier de façon importante. La littérature montre que ces déformations passives peuvent améliorer les performances de p
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31

Clemente, Maria de Lurdes Tavares. "Characterization of antibiotic resistance mechanisms in gram negative bacteria isolated from animals and food products of animal origin." Doctoral thesis, Universidade de Lisboa, Faculdade de Medicina Veterinária, 2018. http://hdl.handle.net/10400.5/15018.

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Tese de Doutoramento em Ciências Veterinárias. Especialidade de Sanidade Animal<br>ABSTRACT - Antibiotics were a truly innovative option in medical therapy for the treatment of diseases caused by microbial agents, having largely contributed for the decrease levels of human and animal morbidity and mortality. Therefore, the overuse and misuse of these drugs in human clinical therapy and in the veterinary medicine, including animal production, contributed for the emergence and dissemination of antibiotic resistant microorganisms, which are a serious threat to human and animal health, and to
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32

McBrayer, Lance D. "Comparative Studies in the Functional Morphology of Lizard Feeding: Kinematics, Behavior, and Biomechanics." Ohio : Ohio University, 2002. http://www.ohiolink.edu/etd/view.cgi?ohiou1037131997.

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33

Özgüç, Özge. "Mechanical and Molecular Regulation of Periodic Cortical Waves of Contraction." Electronic Thesis or Diss., Sorbonne université, 2021. http://www.theses.fr/2021SORUS482.

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Au cours du développement préimplantatoire, l'embryon de mammifère forme le blastocyste, qui est la structure fixant l'embryon dans l'utérus. La formation du blastocyste repose en grande partie sur les forces contractiles générées par le cortex d'actomyosine. Chez la souris, sur des échelles de temps de quelques secondes, nous observons des impulsions de contractions d'actomyosine voyageant périodiquement autour du périmètre cellulaire. Nous appelons ce phénomène vagues de contraction corticale périodique (PeCoWaCo), une manifestation fascinante et mal comprise de la contractilité. Dans cette
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34

Wong, Julian Ling-Chao. "Molecular mechanisms of the animal block to polyspermy /." View online version; access limited to Brown University users, 2005. http://wwwlib.umi.com/dissertations/fullcit/3174518.

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35

Leaper, R. "Animal body-size relationships : patterns, mechanisms and implications." Thesis, University of Aberdeen, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.592927.

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The papers presented here represented an effort to investigate body-size relationships explicitly, using a variety of different approaches, scales of observation and empirical methods, and addressed issues pertinent to several aspects of food web theory, macroecology, and experimental community ecology. At the scale of the food web, (Paper I) the inclusion of parasites in the Ythan food web challenged previous empirical studies of predator-prey body-size relationships and the assumptions underlying food web models. Specifically body-size was neither the determinant of the trophic hierarchy of
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36

Dallison, Agnes, and University of Lethbridge Faculty of Arts and Science. "Mechanisms underlying recovery from early cortical injury in rats." Thesis, Lethbridge, Alta. : University of Lethbridge, Faculty of Arts and Science, 1999, 1999. http://hdl.handle.net/10133/98.

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Previous work has shown that removal of the midline frontal cortex at seven to ten days of age is followed by recovery of function correlated with apparent spontaneous generation of new tissue in the lesion cavity. The question asked in the present thesis was whether the removal of the regrown tissue in adulthood would block normal function. Rats that received P10 frontal lesions underwent second lesions at P160, and were compared to rats with only P10 or P160 lesions. Rats with P10 + P160 lesions were severely impaired on a spatial learning task, especially relative to the P10 lesion-only rat
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37

Tapias, Espinosa Carles. "Schizophrenia-like sensorimotor gating deficits in intact inbred and outbred rats: From behavior to brain mechanisms and back." Doctoral thesis, Universitat Autònoma de Barcelona, 2020. http://hdl.handle.net/10803/671331.

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L’esquizofrènia és una malaltia mental incapacitant que involucra diversos símptomes cognitius, com un filtratge sensoriomotor deteriorat. El filtratge sensoriomotor es pot mesurar mitjançant la inhibició prepols (IPP) de la resposta d’ensurt. Les investigacions en rosegadors sobre l’impacte d’alteracions cerebrals específiques sobre la IPP han estat molt útils per augmentar el coneixement d’aquesta deficiència bàsica de l’esquizofrènia. Aquests estudis mostren que els dèficits en IPP apareixen conjuntament amb altres símptomes, com l’agitació psicomotora, així com alteracions en el circuit co
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38

Remus, Jennifer Lynn. "Neuroimmune Mechanisms of an Animal Model of Recurrent Depression." Kent State University / OhioLINK, 2015. http://rave.ohiolink.edu/etdc/view?acc_num=kent1429197762.

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39

Bansod, Yogesh Deepak. "Computational Simulation of Mechanical Tests of Isolated Animal Cells." Doctoral thesis, Vysoké učení technické v Brně. Fakulta strojního inženýrství, 2016. http://www.nusl.cz/ntk/nusl-263397.

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Buňka tvoří složitý biologický systém vystavený mnoha mimobuněčným mechanickým podnětům. Hlubší pochopení jejího mechanického chování je důležité pro charakterizaci její odezvy v podmínkách zdraví i nemoci. Výpočtové modelování může rozšířit pochopení mechaniky buňky, která může přispívat k vytvoření vztahů mezi strukturou a funkcí různých typů buněk v různých stavech. Za tímto účelem byly pomocí metody konečných prvků (MKP) vytvořeny dva bendotensegritní modely buňky v různých stavech: model vznášející se buňky pro analýzu její globální mechanické odezvy, jako je protažení nebo stlačení, a mo
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40

Dorgan, Kelly M. "Mechanics of Burrowing in Muddy Sediments." Fogler Library, University of Maine, 2007. http://www.library.umaine.edu/theses/pdf/DorganKM2007.pdf.

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41

Kissane, Roger William Peter. "Animal models of exercise therapy : mechanisms of activity-induced angiogenesis." Thesis, University of Leeds, 2017. http://etheses.whiterose.ac.uk/17587/.

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Skeletal muscle is spatially heterogeneous in muscle fibre type composition and microvascular supply. The capacity to quantify this heterogeneity in skeletal muscle is not routinely performed for it’s a laborious and time consuming technique. We have developed a high throughput data pipeline that utilises the simultaneous immunohistochemical labelling of muscle fibre type and microvascular supply, as an input for a semi-automated analysis software package that allows for the analysis of fine morphometric indices of fibre type composition and the interactions with microvascular supply. We have
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42

Berdugo, Claudia. "Cell Damage Mechanisms and Stress Response in Animal Cell Culture." The Ohio State University, 2010. http://rave.ohiolink.edu/etdc/view?acc_num=osu1269467441.

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43

Khalbuss, Walid E. "Electrophysiology, Cell Calcium, and Mechanisms of Hepatocyte Volume Regulation." Digital Commons @ East Tennessee State University, 1990. https://dc.etsu.edu/etd/2709.

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The electrophysiologic technique (Reuss, L., Proc. Natl. Acad. Sci. USA 82:6014, 1985) was modified to measure changes in steady-state hepatocyte volume during osmotic stress. Hepatocytes in mouse liver slices were loaded with tetramethylammonium ion (TMA$\sp{+}$) during transient exposure of cells to nystatin. Intracellular TMA$\sp{+}$ activity (a$\sp{\rm i}\sb{\rm TMA}$) was measured with TMA$\sp{+}$-sensitive, double-barreled microelectrodes. Loading hepatocytes with TMA$\sp{+}$ did not change their membrane potential (V$\sb{\rm m}$), and under steady-state conditions a$\sp{\rm i}\sb{\rm TM
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44

Jeal, Hayley Lorraine. "The immune mechanisms involved in the development of laboratory animal allergy." Thesis, Imperial College London, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.409097.

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45

Webb, Gillian. "Studies on the mechanical transmission of animal viruses by biting flies." Thesis, Open University, 1990. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.278027.

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46

Okuma, Chihiro. "Studies on mechanisms of antiepilepsy and antiobesity in experimental animal models." Kyoto University, 2016. http://hdl.handle.net/2433/215225.

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47

Rowland, Ethan. "Correlation of mechanical stresses with arterial disease frequency in animal models." Thesis, Imperial College London, 2015. http://hdl.handle.net/10044/1/33318.

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Atherosclerosis is a complex inflammatory disease which may be triggered by an elevated transport of lipid-carrying macromolecules from the blood into the arterial wall. Its non-uniform distribution has been attributed to local variations in wall shear stress. Intramural stresses and strains are regularly overlooked, despite their heterogeneous distribution and direct effect on vascular cell morphology and function. Stenotic flow models of atherosclerosis inadvertently alter both fluid and solid stresses. Using a tapered flow modifying cuff, wall uptake of plasma macromolecules was investigate
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48

Eng, Frank Chung Sing 1972. "Molecular mechanisms of estrogen receptor signaling." Thesis, McGill University, 2001. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=38483.

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The estrogen receptor (ER) is a ligand dependent transcriptional activator that belongs to the steroid/nuclear receptor superfamily. To probe the structure and function of the ER ligand binding domain (LBD), we developed a genetic screen in yeast Saccharomyces cerevisiae using a library of reverse ERs screened with a low affinity estrogen agonist, 2-methoxyestrone. Mutants isolated from this screen demonstrated altered ligand binding and/or transactivation properties. One of these mutants, L536P, showed high levels of constitutive activity in several transiently transfected cells and a HeLa li
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49

Zeebaree, Bayar. "Mechanisms of seasonal reproduction in cattle." Thesis, University of Nottingham, 2016. http://eprints.nottingham.ac.uk/38718/.

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This study was conducted to evaluate the effect of season on reproductive parameters in cattle in the temperate climate of the UK. In the first study, reproductive fertility data were collected from a local dairy herd. The results revealed that cows born in autumn were inseminated at an earlier age (P < 0.05) and calved earlier (P < 0.001) than spring and summer born animals. In addition, the conception rate within 90 days after calving was higher (P < 0.05) in autumn calving animals. Conception rate was higher (P < 0.05) when insemination was performed at a temperature range from 7 to 15°C co
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50

Lammers, Andrew R. "The biodynamics of arboreal locomotion in the gray short-tailed opossum ( Monodelphis domestica )." Ohio University / OhioLINK, 2004. http://www.ohiolink.edu/etd/view.cgi?ohiou1102697219.

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