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Teses / dissertações sobre o tema "Bacteriophages"

Autor: Grafiati

Publicado: 4 de junho de 2021

Última modificação: 25 de julho de 2025

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1

Cramer, Todd James Lucas. "Genetic mosaicism between the bacteriophage [phi]80 and bacteriophage [lambda]." Bowling Green, Ohio : Bowling Green State University, 2008. http://rave.ohiolink.edu/etdc/view?acc%5Fnum=bgsu1223514067.

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2

Maillard, Jean-Yves Maillard. "Bacteriophages and biocides." Thesis, Cardiff University, 1994. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.274316.

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3

Wells, Llyd Ewan. "Viral adaptations to life in the cold /." Thesis, Connect to this title online; UW restricted, 2006. http://hdl.handle.net/1773/11056.

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4

Dueñas, Marta. "Phage display and bacterial expression of antibody fragments." Lund : Dept. of Immunotechnology, Lund University, 1995. http://catalog.hathitrust.org/api/volumes/oclc/38164515.html.

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5

Cockburn, Joseph John Berry. "Structural studies on bacteriophages." Thesis, University of Oxford, 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.442832.

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6

Chan, Jacqueline. "Bacteriophages of marine Roseobacter." Thesis, University of Warwick, 2010. http://wrap.warwick.ac.uk/4512/.

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The oceans cover ca. 70% of the Earth’s surface and due to their depth encompass around 300 times the habitable volume of the terrestrial environment. The exact proportion of life on Earth that exists in the oceans is unknown as many ocean species remain undiscovered; in particular this holds true for the viruses that infect marine bacterioplankton. It is currently thought that viruses that infect bacteria, bacteriophages or phages, can numerically exceed their hosts by a factor of ten, however, this abundant and diverse group of organisms is still poorly understood. This is especially true of

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7

Xu, Zinan. "Isolation, characterisation and application of bacteriophages in aquaculture." Thesis, University of Stirling, 2016. http://hdl.handle.net/1893/23740.

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The increasing incidence of infections due to antibiotic resistant bacteria has led to renewed interest in bacteriophages (= phages) and phage therapy. Although phage therapy has been applied to control bacterial diseases in plants, poultry, livestock and humans, its application in aquaculture is still relatively limited. The emergence of phage-resistant bacterial mutants has been considered to be one of the major limitations of phage therapy. This study aimed to (i) isolate and characterise phages; (ii) select phages and their bacterial hosts to set up in vivo phage therapy models with aquacu

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8

Sandegren, Linus. "Group I Introns and Homing Endonucleases in T-even-like Bacteriophages." Doctoral thesis, Stockholm : Institutionen för molekylärbiologi och funktionsgenomik, Univ, 2004. http://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-211.

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9

Varlakova, A., Нiна Володимирiвна Мальована, Нина Владимировна Малеванная, and Nina Volodymyrivna Malovana. "Bacteriophages as alternatives to antibiotics." Thesis, Sumy State University, 2020. https://essuir.sumdu.edu.ua/handle/123456789/77972.

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The history of the discovery of bacteriophages began almost a century ago. In spite of the appearance of antibiotics, bacteriophages are still extremely promising. Bacterial infections are an urgent public health problem, due to the increasing of antibiotic resistance and negative health consequences. Thus, phages are currently considered as an alternative treatment, which are going to replace antibiotics.

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10

Lymer, David. "Significance and Diversity of Lake Bacteriophages." Doctoral thesis, Uppsala : Uppsala universitet, Universitetsbiblioteket, 2008. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-9499.

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11

Guidolin, Angelo. "Molecular biology of "Vibrio cholerae" bacteriophage CP-T1 and its host interactions." Title page, contents and abstract only, 1985. http://web4.library.adelaide.edu.au/theses/09PH/09phg948.pdf.

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12

Williams, Bryan J. "Discovery and characterization of the HP2 phage in haemophilus influenzae." free to MU campus, to others for purchase, 2000. http://wwwlib.umi.com/cr/mo/fullcit?p9998524.

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13

Prabhakaran, Ramanandan. "Factors Affecting Translational Efficiency of Bacteriophages." Thesis, Université d'Ottawa / University of Ottawa, 2015. http://hdl.handle.net/10393/32106.

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Mass production of translationally optimized bacteriophages (hereafter referred to as phages) is the need of the hour in the application of phages to therapy. Understanding translational efficiency of phages is the major preliminary step for mass producing efficient phages. The objective of this thesis is to understand factors affecting translational efficiency of phages. In chapter two, we hypothesized that weak translation initiation efficiency is responsible for weak codon concordance of Escherichia coli lambdoid phages with that of their hosts. We measured the strength of translation init

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14

Andres, Dorothee. "Biophysical chemistry of lipopolysaccharide specific bacteriophages." Phd thesis, Universität Potsdam, 2012. http://opus.kobv.de/ubp/volltexte/2012/5926/.

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Carbohydrate recognition is a ubiquitous principle underlying many fundamental biological processes like fertilization, embryogenesis and viral infections. But how carbohydrate specificity and affinity induce a molecular event is not well understood. One of these examples is bacteriophage P22 that binds and infects three distinct Salmonella enterica (S.) hosts. It recognizes and depolymerizes repetitive carbohydrate structures of O antigen in its host´s outer membrane lipopolysaccharide molecule. This is mediated by tailspikes, mainly β helical appendages on phage P22 short non contractile tai

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15

Hsu, Yu-Hung. "Characterization of Mannheimia haemolytica-specific bacteriophages." Thesis, Lethbridge, Alta. : University of Lethbridge, Dept. of Biological Sciences, c2011, 2011. http://hdl.handle.net/10133/3150.

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Mannheimia haemolytica is the principal bacterial agent associated with bovine respiratory disease (BRD). It has a significant economic impact on the beef feedlot industry. The current methods for BRD prevention and treatment have various problems and limitations, especially with reports of increased antimicrobial resistance in M. haemolytica. Bacteriophage therapy presents a novel method to mitigate M. haemolytica. This study aimed to isolate strictly lytic M. haemolytica-specific bacteriophages from bovine nasopharyngeal swabs and feedlot trough water. This was accompanied by an extensive ch

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16

Rowitch, David Henry. "Structure and assembly of filamentous bacteriophages." Thesis, University of Cambridge, 1987. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.278425.

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17

Al, Kandari Sharifa. "Characterization and comparison of Campylobacter bacteriophages." Thesis, University of Nottingham, 2013. http://eprints.nottingham.ac.uk/14529/.

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Members of the genus Campylobacter are a major cause of food-borne disease worldwide. They can colonize the intestinal mucosa of poultry, to high levels leading to contamination of meat, at slaughter. Their numbers can be reduced in different ways including chicken treatment with bacteriophages. For such treatments to be successful, in depth understanding of the bacteriophage that infects and kills campylobacters is vital. The work in this thesis describes: isolation and comprehensive characterisation of bacteriophage candidates for future therapy applications. In order to increase the availab

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18

Chan, Yi-Wah. "Characterisation of bacteriophages that infect Acaryochloris." Thesis, University of Warwick, 2010. http://wrap.warwick.ac.uk/3127/.

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The cyanobacterium Acaryochloris marina was isolated in 1996 and solved a 50 year old mystery as to the origin of the pigment chlorophyll d, which was thought to be a pigment of red algae or a breakdown product of the universal chlorophyll, chlorophyll a. Over the next decade, new Acaryochloris spp. were isolated from all over the world as the genus received international interest from the scientific community, with the majority of research directed towards understanding the mechanisms of photosynthesis of this uniquely pigmented cyanobacterium, using A. marina as the model organism of the gen

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19

Brathwaite, Kelly Janelle. "Interactions between Campylobacters and their bacteriophages." Thesis, University of Nottingham, 2015. http://eprints.nottingham.ac.uk/28422/.

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Campylobacter jejuni is a leading cause of human bacterial enteritis worldwide. Consumption of contaminated poultry meat is considered a major source of infection. The use of virulent bacteriophages as a form of biocontrol to specifically reduce this pathogen in poultry (phage therapy) is a promising intervention that does not rely on antimicrobials and therefore circumvents the emergence of antibiotic-resistant Campylobacter strains. In order to achieve this, a better understanding of the mechanisms involved in phage-host interactions at the molecular level would assist in the development of

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20

Poon, Pui-wah Alice. "Genetical study of HK253 and related temperate coliphages /." [Hong Kong : University of Hong Kong], 1988. http://sunzi.lib.hku.hk/hkuto/record.jsp?B12358393.

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21

Goh, Shan. "Phenotypic and genotypic characterisation of bacteriophages of Clostridium difficile." University of Western Australia. Microbiology Discipline Group, 2003. http://theses.library.uwa.edu.au/adt-WU2004.0018.

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Clostridium difficile is an important hospital-acquired pathogen causing C. difficile-associated diarrhoea (CDAD) in patients exposed to antibiotics. The lack of information on bacteriophages of C. difficile, and the potential of phages as therapeutic agents for the treatment of CDAD, prompted the isolation and characterisation of phages active against clinical isolates of C. difficile in order to determine the prevalence and significance of phages of this anaerobe. Three (5.4 %) of 56 clinical C. difficile isolates induced by mitomycin C yielded dsDNA phages C2, C5, C6 and C8. The four phages

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22

Harrison, Sharon Jane. "Targeted transgenesis and the 186 site-specific recombination system /." Title page, summary and contents only, 1999. http://web4.library.adelaide.edu.au/theses/09PH/09phh322.pdf.

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23

Storms, Zachary. "Bioprocessing with bacteriophages using self-cycling fermentation." Thesis, McGill University, 2013. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=114211.

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A lack of innovation in production strategies of (bacterio)phages—viruses parasitic to bacteria—has limited recent developments in the applications. New phage-based industries need to develop efficient, large-scale bacteriophage production technologies. In this thesis, parameters affecting the phage infective process such as adsorption, host intracellular genetic material and host cell life cycle were studied; their influence on the production of virulent phages and recombinant proteins using a lysogenized phage as the expression vector is discussed. Self-Cycling Fermentation (SCF), a cyclic

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24

Gregory, Matthew Alan. "Characterisation and evolution of homoimmune Streptomyces bacteriophages." Thesis, University of Nottingham, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.324534.

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25

Taylor, James Gareth William. "Isolation and characterisation of Listeria monocytogenes bacteriophages." Thesis, University of Warwick, 2004. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.425993.

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26

Welsh, Liam Christopher Oswin. "X-ray diffraction studies of filamentous bacteriophages." Thesis, University of Cambridge, 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.627349.

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27

Meader, Emma. "Exploiting bacteriophages to tackle Clostridium difficile infection." Thesis, University of East Anglia, 2013. https://ueaeprints.uea.ac.uk/48147/.

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Clostridium difficile infection (CDI) currently affects around 20,000 people each year, in healthcare institutions and in the community, and will often follow disruption of the gut microbiome. Current treatment strategies call for the use of further antibiotics, of which there is a limited choice. There is a need for additional remedial and prophylactic solutions with greater specificity and low levels of toxicity and resistance. This thesis describes the pathogenesis of CDI, the current treatment strategies and navigates the growing body of studies investigating the potential use of phage. Th

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28

Cselik, Frank. "DNA and protein interactions in filamentous bacteriophages." Thesis, University of Cambridge, 1986. https://www.repository.cam.ac.uk/handle/1810/270397.

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29

SECHAUD, LAURENT. "Caracterisation de 35 bacteriophages de lactobacillus helveticus." Paris 7, 1990. http://www.theses.fr/1990PA077091.

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Lactobacillus helveticus est un lactobacille thermophile caracteristique des levains utilises pour fabriquer les fromages a pate cuite. Ce lactobacille est la cible de bacteriophages specifiques qui detruisent les cellules, ce qui conduit a des produits de qualite mediocre. Jusqu'a present, les phages de l. Helveticus demeuraient largement meconnus. Dans cette etude, 35 phages ont ete caracterises. Vingt-trois d'entre eux avaient ete isoles d'echantillons de lactoserum de fromagerie alors que les 12 autres, temperes, ont ete isoles a partir de surnageants de cultures traitees avec la mc. Tous

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30

RELANO, PURIFICATION. "Caracterisation moleculaire de bacteriophages de bacteries lactiques." Toulouse 3, 1989. http://www.theses.fr/1989TOU30009.

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31

Chang, Jenny Ren-Jye. "Scaffolding-mediated capsid size determination in bacteriophages." Birmingham, Ala. : University of Alabama at Birmingham, 2009. https://www.mhsl.uab.edu/dt/2009p/changj.pdf.

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Thesis (Ph. D.)--University of Alabama at Birmingham, 2009.<br>Title from PDF title page (viewed Jan. 26, 2010). Additional advisors: Asim K. Bej, Gail E. Christie, Peter E. Prevelige, Jr., R. Douglas Watson. Includes bibliographical references.

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32

Mmolawa, Princess Tlou. "Molecular analysis of temperate phages in Salmonella enterica serovar Typhimurium DT 64 isolated in Australia." Title page, contents and summary only, 2001. http://web4.library.adelaide.edu.au/theses/09PH/09phm6855.pdf.

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Files on accompanying CD-ROM: Appendix III Phages ST64T and ST64B sequences, are in rtf format. Bibliography: leaves 279-324. System requirements for accompanying CD-ROM: IBM or compatible ; Microsoft Word or compatible to read rtf files.

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33

Carroll, Sean M. "Evaluation of Virus Removal by Sandy Soils During Soil-Aquifer Treatment Using Indigenous Bacteriophage as Indicator Organisms." Thesis, The University of Arizona, 1996. http://etd.library.arizona.edu/etd/GetFileServlet?file=file:///data1/pdf/etd/azu_etd_hy0197_sip1_w.pdf&type=application/pdf.

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34

Nanduri, Viswaprakash Vodyanoy Vitaly. "Phage at the air-liquid interface for the fabrication of biosensors." Auburn, Ala., 2005. http://hdl.handle.net/10415/1262.

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35

Elmacı, Zehra Seda Arslanoğlu Alper. "Generation of improved E.coli strains to be used in the construction of ligand libraries/." [s.l.]: [s.n.], 2005. http://library.iyte.edu.tr/tezler/master/biyoteknoloji/T000320.pdf.

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Thesis (Master)--İzmir Institute of Technology, İzmir, 2005.<br>Keywords: Phage display technology, bactriophage, homologous recombination, M13, fusion protein. Includes bibliographical references (leaves. 56).

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36

Dibbens, Justin Andrew. "Studies on the control of late gene transcription in coliphage 186 /." Title page, contents and summary only, 1990. http://web4.library.adelaide.edu.au/theses/09PH/09phd543.pdf.

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37

Thanki, Anisha M. "Development of a phage-based diagnostic test for the identification of Clostridium difficile." Thesis, Loughborough University, 2016. https://dspace.lboro.ac.uk/2134/20340.

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Clostridium difficile is the most common bacterial cause of infectious diarrhoea in healthcare environments and in 2014 was responsible for 13,785 infections in the UK. C. difficile infection (CDI) is spread via the faecal-oral route and by contact with contaminated surfaces. However, despite the healthcare concerns no tests are available to validate if sufficient cleaning has been conducted. In addition, Polymerase Chain Reaction (PCR) and Enzyme Immunoassays (EIAs)-based tests used to diagnose CDI lack sensitivity and specificity and hence false negative results are commonly obtained. To ove

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38

Fuller, Derek Nathan. "Single molecule studies of DNA packaging by bacteriophages." Diss., Connect to a 24 p. preview or request complete full text in PDF format. Access restricted to UC campuses, 2008. http://wwwlib.umi.com/cr/ucsd/fullcit?p3296738.

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Thesis (Ph. D.)--University of California, San Diego, 2008.<br>Title from first page of PDF file (viewed March 24, 2008). Available via ProQuest Digital Dissertations. Vita. Includes bibliographical references.

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39

Ermel, Gwennola. "Etudes de bacteriophages virulents de streptocoques lactiques mesophiles." Rennes 1, 1989. http://www.theses.fr/1989REN10121.

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Etude des bacteriophages lytiques des bacteries lactiques. Les analyses morphologiques, de composition proteique et l'homologie adn-adn ont montre que les phages lytiques se repartissent en deux groupes, prolates et isometriques et qu'ils appartiennent a la famille des siphoviridae. L'analyse en microscopie electronique des genomes phagiques a permis d'emettre l'hypothese d'extremites cohesives. L'existence et la nature de celles-ci ont ete mise en evidence par le sequencage d'une partie du genome

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40

Sheflo, Michael Allen. "Characterization of Five Brevibacillus Bacteriophages and Their Genomes." BYU ScholarsArchive, 2016. https://scholarsarchive.byu.edu/etd/6059.

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Brevibacillus laterosporus (B. laterosporus) is a pathogen difficult to distinguish from Paenibacillus larvae (P. larvae), and contributes to Colony Collapse Disorder (CCD) of honeybees. To develop a biocontrol agent to limit its presence, bacteriophages were isolated from Utah County soil samples and used to infect B. laterosporus isolated from Utah County honey and larvae samples. Since CCD is prevalent in Utah beehives, bacteriophage that infect and lyse B. laterosporus may be isolated and characterized. Pathogens were isolated from soil samples, and 16S rRNA gene tests initially identified

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41

Citorik, Robert James. "Development of natural and engineered bacteriophages as antimicrobials." Thesis, Massachusetts Institute of Technology, 2018. https://hdl.handle.net/1721.1/122522.

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Thesis: Ph. D., Massachusetts Institute of Technology, Department of Biology, 2018<br>Cataloged from PDF version of thesis.<br>Includes bibliographical references (pages 89-103).<br>One of the major public health concerns of the modern day is the emergence and spread of extensively antibiotic-resistant pathogens. We have already seen the arrival of infections caused by bacteria resistant to all available antibiotics in the therapeutic arsenal. In addition, we have learned much of the incredible importance of the microbial communities that cohabit our bodies, and of how perturbations to these c

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42

Karunaratne, Desiree Nedra. "Structural investigation and bacteriophage degradation of bacterial polysaccharides." Thesis, University of British Columbia, 1985. http://hdl.handle.net/2429/25832.

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Seventy eight serologically distinct strains of Klebsiella bacteria are known to exist. The capsular polysaccharide surrounding the bacterial cell of these pathogenic Enterobacteria is of immunological significance. Structures of the capsular polysaccharides of nearly sixty seven strains of Klebsiella have been established, and each one found to be unique. The structures of the K antigens from Klebsiella, serotypes K67 and K80 are presented as a contribution to the continuing program of elucidation of the chemical structures of these antigens in an attempt to explain their immunological respon

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43

Gunneriusson, Elin. "Display of affinity proteins on bacteria and bacteriophage /." Stockholm : Department of Biotechnology, Royal Institute of Technology, 1999. http://www.lib.kth.se/abs99/gunn0521.pdf.

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44

Whitworth, Joshua Herbert. "International comparison of shiga toxin-encoding bacteriophage insertion site genotypes of clinical, bovine and environmental E. coli O157 isolates." Online access for everyone, 2008. http://www.dissertations.wsu.edu/Thesis/Spring2008/J_Whitworth_041508.pdf.

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45

Walakira, John Kiremerwa Terhune Jeffery S. "Discovery, isolation and characterization of bacteriophages specific for Edwardsiella ictaluri." Auburn, Ala, 2008. http://repo.lib.auburn.edu/EtdRoot/2008/SPRING/Fisheries_and_Allied_Aquacultures/Thesis/Walakira_John_24.pdf.

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46

Deyoung, Katherine Leigh. "Genetic studies of self-splicing RNAs in bacteriophage T4." Diss., Georgia Institute of Technology, 1993. http://hdl.handle.net/1853/25434.

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47

潘佩華 and Pui-wah Alice Poon. "Genetical study of HK253 and related temperate coliphages." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 1988. http://hub.hku.hk/bib/B31231329.

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48

Car, Nicholas George. "Studies on stationary phase Vibrio sp. 2." Doctoral thesis, University of Cape Town, 1987. http://hdl.handle.net/11427/21894.

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Vibrio sp. 2 stationary phase cells are novel and interesting in that they are able to support phage growth in standing cultures, but not in shaken (aerated) cultures. Many physiological and morphological characteristics change when Vibrio sp. 2 stationary phase cells are removed from aeration: the relatively high levels of protein synthesis (Robb et al., 1977; 1978) decrease, with a concomitant increase in the levels of RNA synthesis; protein degradation rises from 1 %h⁻¹ to 2,9 %h⁻¹, and whilst the average cell length decreases, the range of cell lengths markedly increases. The magic spot nu

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49

Jayanna, Prashanth K. Petrenko Valery. "Therapeutic liposomes for prostate cancer targeted by phage fusion coat proteins." Auburn, Ala., 2009. http://hdl.handle.net/10415/1994.

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50

Wei, Fang. "A bacteriophage recovery methodology for indoor airborne viral infection risk assessment /." View abstract or full-text, 2009. http://library.ust.hk/cgi/db/thesis.pl?MECH%202009%20WEI.

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