Bibliografias temáticas / Breast Carrier proteins. Antioncogenes

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Literatura científica selecionada sobre o tema "Breast Carrier proteins. Antioncogenes"

Autor: Grafiati
Publicado: 4 de junho de 2021
Última modificação: 8 de fevereiro de 2022

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Artigos de revistas sobre o assunto "Breast Carrier proteins. Antioncogenes"

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Zhou, Y., and G. Luo. "Apolipoproteins, as the carrier proteins for lipids, are involved in the development of breast cancer." Clinical and Translational Oncology 22, no. 11 (2020): 1952–62. http://dx.doi.org/10.1007/s12094-020-02354-2.

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Abstract Apolipoproteins, the key components of lipoproteins, play vital roles in the combination and transportation of lipids. Numerous research articles have accumulated solid evidence that lipoproteins are closely related to various types of tumorigenesis. In this review, we focused on the associations between several apolipoproteins and breast carcinoma and distinguished the effects and significance of apolipoproteins in different locations to validate their roles in breast carcinoma development. For example, apoD and apoE in serum are viewed as risk factors for breast carcinoma. ApoD, apo
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Valle, A., J. Sastre-Serra, C. Pol, A. M. Miró, J. Oliver, and P. Roca. "Proteomic Analysis of MCF-7 Breast Cancer Cell Line Exposed To Leptin." Analytical Cellular Pathology 34, no. 3 (2011): 147–57. http://dx.doi.org/10.1155/2011/405253.

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Background: Obesity is a well-known factor risk for breast cancer in postmenopausal women. Circulating leptin levels are increased in obese and it has been suggested to play an important role in mammary tumor formation and progression. To contribute to the understanding of the molecular mechanisms underlying leptin action in breast cancer, our aim was to identify proteins regulated by leptin in MCF-7 human breast cancer cells.Methods: We used two-dimensional gel electrophoresis (2-DE) and matrix assisted laser desorption/ionization time of flight mass spectrometry (MALDI-TOF MS) to identify pr
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Jeon, Young Joo, Sihem Khelifa, Boris Ratnikov, et al. "Regulation of Glutamine Carrier Proteins by RNF5 Determines Breast Cancer Response to ER Stress-Inducing Chemotherapies." Cancer Cell 27, no. 3 (2015): 354–69. http://dx.doi.org/10.1016/j.ccell.2015.02.006.

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Haque, Sheikh Tanzina, Rowshan Ara Islam, Siew Hua Gan, and Ezharul Hoque Chowdhury. "Characterization and Evaluation of Bone-Derived Nanoparticles as a Novel pH-Responsive Carrier for Delivery of Doxorubicin into Breast Cancer Cells." International Journal of Molecular Sciences 21, no. 18 (2020): 6721. http://dx.doi.org/10.3390/ijms21186721.

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Background: The limitations of conventional treatment modalities in cancer, especially in breast cancer, facilitated the necessity for developing a safer drug delivery system (DDS). Inorganic nano-carriers based on calcium phosphates such as hydroxyapatite (HA) and carbonate apatite (CA) have gained attention due to their biocompatibility, reduced toxicity, and improved therapeutic efficacy. Methods: In this study, the potential of goose bone ash (GBA), a natural derivative of HA or CA, was exploited as a pH-responsive carrier to successfully deliver doxorubicin (DOX), an anthracycline drug in
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Yen, Meng-Chi, Shih-Kai Chou, Jung-Yu Kan, Po-Lin Kuo, Ming-Feng Hou, and Ya-Ling Hsu. "Solute Carrier Family 27 Member 4 (SLC27A4) Enhances Cell Growth, Migration, and Invasion in Breast Cancer Cells." International Journal of Molecular Sciences 19, no. 11 (2018): 3434. http://dx.doi.org/10.3390/ijms19113434.

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Fatty acid metabolism is important in the regulation of breast cancer progression. Some of the proteins involved in fatty acid transport have been demonstrated to promote the proliferation, migration, and invasion in breast cancer cells. Solute carrier family 27 member 4 (SLC27A4) is a fatty acid transporter protein and is related to very long chain acyl-CoA synthetase activity. In the present study, bioinformatic analysis revealed that relatively high SLC27A4 expression was observed in all subtypes of breast tumor tissues when compared to normal breast tissues. Silencing SLC27A4 expression si
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Ahmed, Hamidu, Mokrish Ajat, Rana I. Mahmood, et al. "LC-MS/MS Proteomic Study of MCF-7 Cell Treated with Dox and Dox-Loaded Calcium Carbonate Nanoparticles Revealed Changes in Proteins Related to Glycolysis, Actin Signalling, and Energy Metabolism." Biology 10, no. 9 (2021): 909. http://dx.doi.org/10.3390/biology10090909.

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One of the most prevalent death causes among women worldwide is breast cancer. This study aimed to characterise and differentiate the proteomics profiles of breast cancer cell lines treated with Doxorubicin (DOX) and Doxorubicin-CaCO3-nanoparticles (DOX-Ar-CC-NPs). This study determines the therapeutic potential of doxorubicin-loaded aragonite CaCO3 nanoparticles using a Liquid Chromatography/Mass Spectrometry analysis. In total, 334 proteins were expressed in DOX-Ar-CC-NPs treated cells, while DOX treatment expressed only 54 proteins. Out of the 334 proteins expressed in DOX-CC-NPs treated ce
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Engel, Jörg B., Andrew V. Schally, Gabor Halmos, Benjamin Baker, Attila Nagy, and Gunhild Keller. "Targeted cytotoxic bombesin analog AN-215 effectively inhibits experimental human breast cancers with a low induction of multi-drug resistance proteins." Endocrine-Related Cancer 12, no. 4 (2005): 999–1009. http://dx.doi.org/10.1677/erc.1.01022.

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The cytotoxic analog of bombesin (BN)/gastrin releasing peptide (GRP) AN-215 consisting of 2-pyrrolinodoxorubicin (AN-201), a superactive derivative of doxorubicin linked to a bombesin analog carrier, displays a high affinity to BN/GRP receptors and can be targeted to tumors that express these receptors. We evaluated the antitumor effect and the toxicity of AN-215 in 5 human breast cancer cell lines xenografted into nude mice. In addition, we measured the mRNA expression of multi drug resistance protein 1 (MDR-1), multi drug resistance related protein 1 (MRP-1) and breast cancer resistance pro
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Nordin, Noraini, Swee Keong Yeap, Heshu Sulaiman Rahman, et al. "Antitumor and Anti-Metastatic Effects of Citral-Loaded Nanostructured Lipid Carrier in 4T1-Induced Breast Cancer Mouse Model." Molecules 25, no. 11 (2020): 2670. http://dx.doi.org/10.3390/molecules25112670.

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Cancer nano-therapy has been progressing rapidly with the introduction of many novel drug delivery systems. The previous study has reported on the in vitro cytotoxicity of citral-loaded nanostructured lipid carrier (NLC-Citral) on MDA-MB-231 cells and some preliminary in vivo antitumor effects on 4T1 breast cancer cells challenged mice. However, the in vivo apoptosis induction and anti-metastatic effects of NLC-Citral have yet to be reported. In this study, the in vitro cytotoxic, anti-migration, and anti-invasion effects of NLC-Citral were tested on 4T1 breast cancer cells. In addition, the i
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Watson, Patrice, Rita Lieberman, Carrie Snyder, Vanessa J. Clark, Henry T. Lynch, and Jeffrey T. Holt. "Detecting BRCA2 Protein Truncation in Tissue Biopsies to Identify Breast Cancers That Arise in BRCA2 Gene Mutation Carriers." Journal of Clinical Oncology 27, no. 24 (2009): 3894–900. http://dx.doi.org/10.1200/jco.2008.20.5211.

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Purpose Mutations in the BRCA2 gene are dominantly inherited but cause cancers when the wild-type allele has loss of heterozygosity (LOH) within the cancer. Because most disease-associated BRCA2 mutations are protein-truncating mutations, a test for truncated BRCA2 proteins should identify most BRCA2 hereditary cancers. Methods We have developed a tissue truncation test to identify truncated BRCA2 proteins in breast cancer tissue biopsies in vivo that does not use amplification or genetic manipulations. N-terminal and C-terminal antibodies are used to visualize protein truncation by demonstrat
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Markovsky, Aleksandr V. "ADDITIVE EFFECT OF GENES POLYMORPHISM OF FOLATE CYCLE PROTEINS AND HOMOCYSTEIN LEVEL IN PATIENTS WITH PROLIFERATIVE DISEASES OF THE BREAST AS A POTENTIAL FACTOR OF THE RISK OF THROMBOSSES." Atherothrombosis Journal, no. 2 (December 27, 2018): 46–53. http://dx.doi.org/10.21518/2307-1109-2018-2-46-53.

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Aim.The aim of study was to examine the relationship between serum and mammary gland homocysteine levels with the carrier of separate SNP (single nucleotide polymorphism) genes of the folate metabolism system in patients with proliferative diseases and breast cancer.Methods and results.The study included 182 patients with proliferative diseases of the mammary gland in transbaikalia. The control group included 144 women who did not have oncological diseases. The serum homocysteine level and the supernatant of the mammary tissue homogenate were evaluated by high performance liquid chromatography
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Teses / dissertações sobre o assunto "Breast Carrier proteins. Antioncogenes"

1

Cheng, Wan-biu. "Genetic analysis on the EPHB2 gene in breast cancer /." View the Table of Contents & Abstract, 2005. http://sunzi.lib.hku.hk/hkuto/record/B31494316.

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Cheng, Wan-biu, and 鄭雲標. "Genetic analysis on the EPHB2 gene in breast cancer." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2005. http://hub.hku.hk/bib/B45009946.

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Silveira, Alexandra C. "Characterization of SUDS3 as a BRMS1 family member in breast cancer." Thesis, Birmingham, Ala. : University of Alabama at Birmingham, 2008. https://www.mhsl.uab.edu/dt/2008p/silveira.pdf.

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Behmoaram, Emy. "Biological studies of fascin function in cancer cell invasion and cancer progression." Thesis, McGill University, 2008. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=111596.

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The process of metastasis is initiated through the acquisition of inherent and autonomous motile and invasive properties by tumor cells. These phenomena are initiated through a balance between forward cancer cell membrane protrusion and tail retraction, and occur via cell cytoskeleton remodeling, actin reorganization, and coordinated focal adhesion assembly and disassembly events. Among the vast network of cytoskeletal proteins, the actin-bundling protein fascin plays a major function in cell cytoskeleton remodeling. It is a 55-kDa protein involved in the formation of filopodia and cell migrat
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Phelps, Mitch A. "Novel approaches for characterizing the riboflavin transport and trafficking mechanism and its potential as a target in breast cancer." Columbus, Ohio : Ohio State University, 2005. http://rave.ohiolink.edu/etdc/view?acc%5Fnum=osu1133261831.

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