Bibliografias temáticas / CNOT3

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Literatura científica selecionada sobre o tema "CNOT3"

Autor: Grafiati
Publicado: 14 de dezembro de 2024
Última modificação: 31 de julho de 2025

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Artigos de revistas sobre o assunto "CNOT3"

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Mittal, Saloni, Akhmed Aslam, Rachel Doidge, Rachel Medica, and G. Sebastiaan Winkler. "The Ccr4a (CNOT6) and Ccr4b (CNOT6L) deadenylase subunits of the human Ccr4–Not complex contribute to the prevention of cell death and senescence." Molecular Biology of the Cell 22, no. 6 (2011): 748–58. http://dx.doi.org/10.1091/mbc.e10-11-0898.

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A key step in cytoplasmic mRNA degradation is the shortening of the poly(A) tail, which involves several deadenylase enzymes. Relatively little is known about the importance of these enzymes for the cellular physiology. Here we focused on the role of the highly similar Ccr4a (CNOT6) and Ccr4b (CNOT6L) deadenylase subunits of the Ccr4–Not complex. In addition to a role in cell proliferation, Ccr4a and Ccr4b play a role in cell survival, in contrast to the Caf1a (CNOT7) and Caf1b (CNOT8) deadenylase subunits or the CNOT1 and CNOT3 noncatalytic subunits of the Ccr4–Not complex. Underscoring the d
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Zheng, Xiaofeng, Raluca Dumitru, Brad L. Lackford, et al. "Cnot1, Cnot2, and Cnot3 Maintain Mouse and Human ESC Identity and Inhibit Extraembryonic Differentiation." STEM CELLS 30, no. 5 (2012): 910–22. http://dx.doi.org/10.1002/stem.1070.

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Elmén, Lisa, Claudia B. Volpato, Anaïs Kervadec, et al. "Silencing of CCR4-NOT complex subunits affects heart structure and function." Disease Models & Mechanisms 13, no. 7 (2020): dmm044727. http://dx.doi.org/10.1242/dmm.044727.

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ABSTRACTThe identification of genetic variants that predispose individuals to cardiovascular disease and a better understanding of their targets would be highly advantageous. Genome-wide association studies have identified variants that associate with QT-interval length (a measure of myocardial repolarization). Three of the strongest associating variants (single-nucleotide polymorphisms) are located in the putative promotor region of CNOT1, a gene encoding the central CNOT1 subunit of CCR4-NOT: a multifunctional, conserved complex regulating gene expression and mRNA stability and turnover. We
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McLenachan, Samuel, Dan Zhang, Janya Grainok, et al. "Determinants of Disease Penetrance in PRPF31-Associated Retinopathy." Genes 12, no. 10 (2021): 1542. http://dx.doi.org/10.3390/genes12101542.

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Retinitis pigmentosa 11 (RP11) is caused by dominant mutations in PRPF31, however a significant proportion of mutation carriers do not develop retinopathy. Here, we investigated the relationship between CNOT3 polymorphism, MSR1 repeat copy number and disease penetrance in RP11 patients and non-penetrant carriers (NPCs). We further characterized PRPF31 and CNOT3 expression in fibroblasts from eight RP11 patients and one NPC from a family carrying the c.1205C>T variant. Retinal organoids (ROs) and retinal pigment epithelium (RPE) were differentiated from induced pluripotent stem cells derived
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Díaz-Peña, Roberto, Ana M. Aransay, Beatriz Suárez-Álvarez, et al. "A high density SNP genotyping approach within the 19q13 chromosome region identifies an association of a CNOT3 polymorphism with ankylosing spondylitis." Annals of the Rheumatic Diseases 71, no. 5 (2012): 714–17. http://dx.doi.org/10.1136/annrheumdis-2011-200661.

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ObjectiveTo identify genomic variants in the 19q13 chromosome region associated with ankylosing spondylitis (AS) in human leucocyte antigen (HLA)-B27-positive populations.MethodsHigh-throughput genotyping of 1536 haplotype-tag single nucleotide polymorphisms (SNPs) was performed in 249 patients with AS and 302 healthy controls. Some of the identified associations were validated by genotyping four SNPs in two additional cohorts consisting of 412 cases/301 controls and 144 cases/203 controls. All individuals selected (both cases and controls) were HLA-B27-positive.ResultsTwo markers in two diffe
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Banowska, Lidia. "Ironia, cnota i „strach śmieszności”. (Herbert – Norwid)." Studia Norwidiana 40 (September 13, 2022): 37–56. http://dx.doi.org/10.18290/sn2240.2.

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Artykuł dotyczy związku ironii oraz cnoty w poezji Cypriana Norwida oraz Zbigniewa Herberta jako pojęć kluczowych dla twórczości obu autorów i sytuuje się w obszarze badań nad tradycją norwidowską w pisarstwie autora Pana Cogito. Słynny wiersz Herberta Pan Cogito o cnocie zostaje potraktowany jako studium przypadku. Na podstawie interpretacji tego tekstu autorka stawia tezę, iż obrazową matrycą myślenia Herberta o cnocie była wyobraźnia ironiologiczna autora Quidama, a ironia odsłania się jako jedna z możliwych konkretyzacji cnoty. Podstawę dla budowania obrazowych przedstawień obu pojęć stano
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Szram, Mariusz. "Can humility exist without poverty? A response by Cappadocian Fathers and John Chrysostom." Vox Patrum 62 (September 4, 2014): 505–10. http://dx.doi.org/10.31743/vp.3599.

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Greccy Ojcowie Kościoła IV w. uznawali zgodnie cnotę pokory za punkt wyjścia na drodze duchowego doskonalenia oraz za matkę wszystkich cnót. W duchu rozwijającego się monastycyzmu podkreślali przede wszystkim ścisły związek pokory z posłuszeństwem jako cnotą najbardziej jej pokrewną. Autor artykułu stara się znaleźć odpowiedź na pytanie, w jaki sposób postrzegali oni re­lację między pokorą i ubóstwem, mającą głęboką tradycję biblijną. Już w Starym Testamencie ludzie ubodzy (ptoco…) jako znajdujący się w potrzebie byli uważa­ni za szczególnie skromnych i otwartych na pokorne szukanie pomocy u B
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Inoue, Takeshi, Masahiro Morita, Atsushi Hijikata, et al. "CNOT3 contributes to early B cell development by controlling Igh rearrangement and p53 mRNA stability." Journal of Experimental Medicine 212, no. 9 (2015): 1465–79. http://dx.doi.org/10.1084/jem.20150384.

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The CCR4–NOT deadenylase complex plays crucial roles in mRNA decay and translational repression induced by poly(A) tail shortening. Although the in vitro activities of each component of this complex have been well characterized, its in vivo role in immune cells remains unclear. Here we show that mice lacking the CNOT3 subunit of this complex, specifically in B cells, have a developmental block at the pro- to pre–B cell transition. CNOT3 regulated generation of germline transcripts in the VH region of the immunoglobulin heavy chain (Igh) locus, compaction of the locus, and subsequent Igh gene r
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Rodriguez-Gil, Alfonso, Olesja Ritter, Juliane Hornung, et al. "HIPK family kinases bind and regulate the function of the CCR4-NOT complex." Molecular Biology of the Cell 27, no. 12 (2016): 1969–80. http://dx.doi.org/10.1091/mbc.e15-09-0629.

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The serine/threonine kinase HIPK2 functions as a regulator of developmental processes and as a signal integrator of a wide variety of stress signals, such as DNA damage, hypoxia, and reactive oxygen intermediates. Because the kinase is generated in a constitutively active form, its expression levels are restricted by a variety of different mechanisms. Here we identify the CCR4-NOT complex as a new regulator of HIPK2 abundance. Down-regulation or knockout of the CCR4-NOT complex member CNOT2 leads to reduced HIPK2 protein levels without affecting the expression level of HIPK1 or HIPK3. A fracti
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Głąb, Anna. "Cnota, charakter, dobroć. W nawiązaniu do powieści autobiograficznej Raimonda Gaity Mój ojciec Romulus." Roczniki Filozoficzne 68, no. 1 (2020): 49–75. http://dx.doi.org/10.18290/rf20681-3.

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Przedmiotem tekstu jest rozróżnienie między dobrocią i cnotą oraz złem i występkiem, wprowadzone przez Hannah Arendt na podstawie lektury powieści Hermanna Melville’a Billy Budd. Rozróżnienie to analizuję, odnosząc się do historii życia Romulusa Gaity, bohatera powieści autobiograficznej Mój ojciec Romulus, której autorem jest australijski etyk Raimond Gaita. W paragrafie 1 zajmuję się ową dystynkcją, wskazując na przewartościowanie takich pojęć, jak cnota i występek w powieści Melville’a oraz jego rozumienie cnoty. Następnie (paragraf 2) staram się odpowiedzieć na pytanie, dlaczego Gaita pisz
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Teses / dissertações sobre o assunto "CNOT3"

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Martufi, Matteo. "Role of Cnot3 in gene regulation and cell cycle progression." Thesis, Imperial College London, 2014. http://hdl.handle.net/10044/1/24778.

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Gene expression is a process that is tightly regulated by many factors. Different genes are transcribed not only in a cell specific manner but are also differentially expressed at different stages of the cell cycle. Cnot3 is part of the CCR4-NOT deadenylation complex, which is involved in the turnover of mRNAs in the cytoplasm and has also been shown to have roles in regulating transcription and cell proliferation and in maintaining ES cell pluripotency. Previous work demonstrated that Cnot3 interacts directly with Aurora B kinase and is phosphorylated by Aurora B in an in vitro assay. Aurora
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Doidge, Rachel L. "The anti-proliferative activity of BTG/TOB proteins is mediated via the Caf1a (CNOT7)/Caf1b (CNOT8) deadenylase enzymes." Thesis, University of Nottingham, 2013. http://eprints.nottingham.ac.uk/13012/.

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The human BTG/TOB protein family comprises six members (BTG1, BTG2/PC3/Tis21, BTG3/Ana, BTG4/PC3B, TOB1/Tob, and TOB2) that display anti-proliferative activity in a number of cell types. They are characterised by a conserved N-terminal BTG domain that mediates interactions with the Caf1a (CNOT7) and Caf1b (CNOT8) deadenylases. It was unclear whether the anti-proliferative activity of the BTG/TOB proteins was mediated through interactions with Caf1a (CNOT7) and Caf1b (CNOT8). To address this we further characterised the amino acid residues located along the BTG2 and TOB1 interaction surface wit
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Engel, Camille. "Description phénotypique de formes rares de trouble du développement intellectuel et caractérisation des mécanismes moléculaires impliqués." Electronic Thesis or Diss., Bourgogne Franche-Comté, 2024. http://www.theses.fr/2024UBFCE006.

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L’avènement des nouvelles techniques de séquençage a permis d’augmenter de façon considérable le taux diagnostique des troubles du développement intellectuel (TDI) et plus de 2000 gènes impliqués sont aujourd’hui connus. Malgré ces progrès considérables, l’interprétation des variants identifiés par les techniques de séquençage reste parfois difficile et l’histoire naturelle des TDI nouvellement décrits est souvent méconnue. Notre travail a consisté à étudier quatre formes de TDI rares de modes de transmissionvariés sur les plans clinique et génétique afin de mieux comprendre ces affections et
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McFleder, Rhonda L. "Regulation of Local Translation, Synaptic Plasticity, and Cognitive Function by CNOT7." eScholarship@UMMS, 2017. https://escholarship.umassmed.edu/gsbs_diss/915.

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Local translation of mRNAs in dendrites is vital for synaptic plasticity and learning and memory. Tight regulation of this translation is key to preventing neurological disorders resulting from aberrant local translation. Here we find that CNOT7, the major deadenylase in eukaryotic cells, takes on the distinct role of regulating local translation in the hippocampus. Depletion of CNOT7 from cultured neurons affects the poly(A) state, localization, and translation of dendritic mRNAs while having little effect on the global neuronal mRNA population. Following synaptic activity, CNOT7 is rapidly d
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Oliveira, Maria do Socorro Ribeiro de. "Contribuições para comunicação e computação quânticas: análise do PMD e PDL em um sistema de DQC, geração de um estado entrelaçado de quatro modos e uma porta CNOT para qubits de estados coerentes." reponame:Repositório Institucional da UFC, 2013. http://www.repositorio.ufc.br/handle/riufc/10869.

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OLIVEIRA. M. S. R. Contribuições para comunicação e computação quânticas: análise do PMD e PDL em um sistema de DQC, geração de um estado entrelaçado de quatro modos e uma porta CNOT para qubits de estados coerentes. 2013. 60 f. Dissertação (Mestrado em Engenharia de Teleinformática) - Centro de Tecnologia, Universidade Federal do Ceará, Fortaleza, 2013.<br>Submitted by Marlene Sousa (mmarlene@ufc.br) on 2015-02-27T16:34:03Z No. of bitstreams: 1 2013_dis_msroliveira.pdf: 1514414 bytes, checksum: a6c9d9ebe5e73e7933bbb4f387ec9e14 (MD5)<br>Approved for entry into archive by Marlene Sousa(mmarl
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Goubault, de Brugière Timothée. "Methods for optimizing the synthesis of quantum circuits Quantum CNOT Circuits Synthesis for NISQ Architectures Using the Syndrome Decoding Problem Quantum circuits synthesis using Householder transformations Synthesizing quantum circuits via numerical optimization Reuse method for quantum circuit synthesis." Thesis, université Paris-Saclay, 2020. http://www.theses.fr/2020UPASG018.

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Pour exécuter un algorithme abstrait sur un ordinateur quantique il faut compiler l'algorithme en une séquence d'instructions bas niveau exécutables par le processeur. L'étape de compilation est cruciale car elle détermine la quantité de ressources nécessaire pour l'exécution d'un algorithme ; par conséquent elle se doit d'être optimisée. Dans cette thèse nous nous intéressons à une brique de la compilation~: la synthèse de circuits quantiques à partir d'une spécification abstraite d'un opérateur. Dans un premier temps nous étudions le cas où la matrice unitaire d'un opérateur quantique nous e
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Pasquini, Michael. "Computer quantistici a ioni intrappolati." Bachelor's thesis, Alma Mater Studiorum - Università di Bologna, 2021. http://amslaurea.unibo.it/24678/.

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L'obiettivo di questo elaborato è di dare una descrizione generale del funzionamento di un computer quantistico a ioni intrappolati, dal confinamento degli ioni in trappole unidimensionali fino all’implementazione delle porte logiche. Partendo dalla descrizione della trappola ionica di Paul che confina gli ioni tramite un potenziale di tipo armonico, si è poi descritto in che modo è possibile modificare lo stato interno degli ioni tramite l’interazione con il campo elettromagnetico generato da un laser esterno Si è esaminato nel dettaglio quali sono le principali tipologie di gate a sin
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Tsai, Dung-Bang, and 蔡東邦. "Optimal Control of CNOT gate." Thesis, 2008. http://ndltd.ncl.edu.tw/handle/17370157583852447562.

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碩士<br>國立臺灣大學<br>物理研究所<br>96<br>We investigate how pulse-sequences and operation times of elementary quantum gates can be optimized for silicon-based donor electron spin quantum computer architecture, complementary to the original Kane''s nuclear spin proposal. This gate-sequence-optimal or time-optimal quantum gate control in a quantum circuit is in addition to the more conventional concept of optimality in terms of the number of elementary gates needed in a quantum transformation. The optimal control method we use is the so-called gradient ascent pulse engineering (GRAPE) scheme. We focus on
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Tsai, Dung-Bang. "Optimal Control of CNOT gate." 2008. http://www.cetd.com.tw/ec/thesisdetail.aspx?etdun=U0001-1507200819593900.

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Lin, Yu-Chen, and 林育楨. "The Role of CNOT4 E3 Ubiquitin ligase in Influenza A virus replication." Thesis, 2014. http://ndltd.ncl.edu.tw/handle/78341434155778519053.

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碩士<br>國立陽明大學<br>生命科學系暨基因體科學研究所<br>102<br>Abstract Influenza A virus (IAV) is an enveloped RNA virus. Its genome consists of eight single-stranded negative-sense RNAs that encode 12 viral proteins. Each viral RNA segment is packaged with viral nucleoprotein (NP) and RNA-dependent RNA polymerase complex (PB1, PB2 and PA) to form viral ribonucleoprotein (vRNP) complexes. Our previous report showed that NP is a mono-ubiquitinated protein and can be specifically deubiquitinated by cellular deubiquitinase USP11. Ubiquitination of NP could alter the interaction of NP with viral RNA, and USP11 can cle
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Livros sobre o assunto "CNOT3"

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Zulawski, Andrzej. Cnota. Wydawnictwo Ksiazkowe "Twoj Styl", 2005.

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Lasocińska, Estera. "Cnota sama z mądrością jest naszym żywotem": Stoickie pojęcie cnoty w poezji polskiej XVII wieku. IBL, 2003.

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Marie, Robertson Eleanor. Bezwstydna cnota. Wydawnictwo Amber, 2009.

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Szczypiorski, Andrzej. Grzechy, cnoty, pragnienia. Sens, 1997.

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Korolec, Jerzy B. Wolność, cnota, praxis. Wydawn. Instytutu Filozofii i Socjologii Polskiej Akademii Nauk, 2006.

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Rzeszowski, Uniwersytet, ed. Cnoty: Eseje z filozofii kultury. Wydawnictwo Uniwersytetu Rzeszowskiego, 2016.

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Przybyszewski, Bolesław. Błogosławiona Jadwiga królowa: Zdobna w cnoty. 2nd ed. Wydawn. Św. Stanisława B.M. Archidiecezji Krakowskiej, 1996.

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Przybyszewski, Bolesław. Święta Jadwiga Królowa: Zdobna w cnoty. 3rd ed. Wydawn. Św. Stanisława BM Archidiecezji Krakowskiej, 1997.

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Witold, Filler, and Lipiński Eryk, eds. Szpilki 1935-1985: Z dziejów cnoty. Krajowa Agencja Wydawnicza, 1985.

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S, Szczepański Marek, Rojek Paulina 1976-, and Wyższa Szkoła Zarządzania i Nauk Społecznych w Tychach., eds. Cnoty i instytucje obywatelskie w społeczności lokalnej. Śląskie Wydawnictwa Naukowe, Wyższa Szkoła Zarządzania i Nauk Społecznych w Tychach, 2001.

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Capítulos de livros sobre o assunto "CNOT3"

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Dumitru, Raluca, and Guang Hu. "Maintenance of Human Embryonic Stem Cell Identity and Inhibition of Extraembryonic Differentiation: Role of CNOT1, CNOT2 and CNOT3." In Stem Cells and Cancer Stem Cells, Volume 11. Springer Netherlands, 2013. http://dx.doi.org/10.1007/978-94-007-7329-5_1.

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Jain, M., and A. Gupta. "2641 Diamagnetic susceptibility of CNOTl." In Diamagnetic Susceptibility and Anisotropy of Inorganic and Organometallic Compounds. Springer Berlin Heidelberg, 2007. http://dx.doi.org/10.1007/978-3-540-44694-1_2642.

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Just, Bettina. "CNOT – ein Quantengatter auf zwei QBits." In Quantencomputing kompakt. Springer Berlin Heidelberg, 2020. http://dx.doi.org/10.1007/978-3-662-61889-9_10.

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Grześkowiak-Krwawicz, Anna. "Cnota – Virtue as Advice for the Commonwealth." In The Political Discourse of the Polish-Lithuanian Commonwealth. Routledge, 2020. http://dx.doi.org/10.4324/9780367823535-8.

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Meuli, Giulia, Mathias Soeken, and Giovanni De Micheli. "SAT-based {CNOT, T} Quantum Circuit Synthesis." In Reversible Computation. Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-99498-7_12.

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Wong, Hiu Yung. "Quantum Gate Introduction: NOT and CNOT Gates." In Introduction to Quantum Computing. Springer International Publishing, 2023. http://dx.doi.org/10.1007/978-3-031-36985-8_15.

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Just, Bettina. "CNOT: A Quantum Gate on Two Qubits." In Quantum Computing Compact. Springer Berlin Heidelberg, 2022. http://dx.doi.org/10.1007/978-3-662-65008-0_10.

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Christensen, Jens Emil, Søren Fuglede Jørgensen, Andreas Pavlogiannis, and Jaco van de Pol. "On Exact Sizes of Minimal CNOT Circuits." In Lecture Notes in Computer Science. Springer Nature Switzerland, 2025. https://doi.org/10.1007/978-3-031-97063-4_6.

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Felloni, Sara, and Giuliano Strini. "An Error Model for the Cirac-Zoller cnot Gate." In Lecture Notes of the Institute for Computer Sciences, Social Informatics and Telecommunications Engineering. Springer Berlin Heidelberg, 2010. http://dx.doi.org/10.1007/978-3-642-11731-2_25.

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Niemann, Philipp, Luca Müller, and Rolf Drechsler. "Finding Optimal Implementations of Non-native CNOT Gates Using SAT." In Reversible Computation. Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-79837-6_15.

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Trabalhos de conferências sobre o assunto "CNOT3"

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Wang, Hanyu, Jason Cong, and Giovanni De Micheli. "Quantum State Preparation Using an Exact CNOT Synthesis Formulation." In 2024 Design, Automation & Test in Europe Conference & Exhibition (DATE). IEEE, 2024. http://dx.doi.org/10.23919/date58400.2024.10546633.

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Choure, Kamalkishor, Manisha Prajapat, Ankur Saharia, et al. "Silicon nitride ring resonators based all-optical CNOT logic gate." In Optical Technologies for Telecommunications 2023, edited by Oleg G. Morozov, Albert C. Sultanov, and Anton V. Bourdine. SPIE, 2024. http://dx.doi.org/10.1117/12.3026516.

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Clarino, David, Kyouhei Seino, Atsushi Matsuo, and Shigeru Yamashita. "Utilizing Don't-Cares to Minimize CNOTs in Synthesizing NNA Compliant Quantum Circuits." In 2024 IEEE International Conference on Quantum Computing and Engineering (QCE). IEEE, 2024. https://doi.org/10.1109/qce60285.2024.10375.

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Hinton, Chris, and Madeleine Belisle. "cNOTE." In ACM SIGGRAPH 2006 Art gallery. ACM Press, 2006. http://dx.doi.org/10.1145/1178977.1179101.

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Wang, Qianke, Jun Liu, Dawei Lyu, and Jian Wang. "Experimental Demonstration of A Spatial Mode Quantum Gate Assisted by Diffractive Deep Neural Networks." In CLEO: QELS_Fundamental Science. Optica Publishing Group, 2022. http://dx.doi.org/10.1364/cleo_qels.2022.ff3j.4.

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We demonstrate a quantum controlled-NOT (CNOT) gate operating on spatial modes of single photons. The CNOT gate is implemented by a series of spatially separated phase plates generated by diffractive deep neural networks (D2NNs).
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Chen, Yanzhu, Linghua Zhu, Nicholas J. Mayhall, Edwin Barnes, and Sophia E. Economou. "How Much Entanglement Do Quantum Optimization Algorithms Require?" In Quantum 2.0. Optica Publishing Group, 2022. http://dx.doi.org/10.1364/quantum.2022.qm4a.2.

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ADAPT-QAOA, a novel problem-tailored version of quantum approximate optimization algorithm, speeds up convergence using entangling operators while reducing the total number of CNOTs. We explore how much entanglement is required to speed up optimization algorithms.
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Ashhab, Sahel, Naoki Yamamoto, Fumiki Yoshihara, and Kouichi Semba. "Numerical analysis of quantum circuits for state preparation and unitary operator synthesis." In Quantum 2.0. Optica Publishing Group, 2023. http://dx.doi.org/10.1364/quantum.2023.qm4b.7.

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We use numerical optimal-control-theory techniques to calculate the number of CNOT gates needed to perform quantum state preparation and unitary operator synthesis. Our approach pro-vides new results and previously inaccessible insight.
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Domínguez-Serna, F. A. "A CNOT Proposal for Temporal-Mode Qubits Based on the Difference Frequency Generation Process." In Frontiers in Optics. Optica Publishing Group, 2023. http://dx.doi.org/10.1364/fio.2023.jtu5a.53.

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Multiple proposals exist for implementing quantum operations on light-based qubits. We propose a nonlinear optics approach using the Difference Frequency Generation process for probabilistic CNOT gates in color qubits, analogous to polarization-based operations [1].
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Lukac, Martin, Kamila Abdiyeva, and Michitaka Kameyama. "CNOT-Measure Quantum Neural Networks." In 2018 IEEE 48th International Symposium on Multiple-Valued Logic (ISMVL). IEEE, 2018. http://dx.doi.org/10.1109/ismvl.2018.00040.

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García-Escartín, Juan Carlos, Pedro Chamorro-Posada, and Alexander Lvovsky. "Optical CNOT gates with Quantum Interrogation." In QUANTUM COMMUNICATION, MEASUREMENT AND COMPUTING (QCMC): Ninth International Conference on QCMC. AIP, 2009. http://dx.doi.org/10.1063/1.3131358.

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