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Artigos de revistas sobre o tema "Coenzyme Q"

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1

Matthews, P. M., e D. L. Arnold. "Coenzyme Q". Neurology 43, n.º 3, Part 1 (1 de março de 1993): 628. http://dx.doi.org/10.1212/wnl.43.3_part_1.628.

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2

Bendahan, D., G. K. Ribbens e P. J. Cozzone. "Coenzyme Q". Neurology 43, n.º 3, Part 1 (1 de março de 1993): 628. http://dx.doi.org/10.1212/wnl.43.3_part_1.628-a.

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3

Mortensen, Svend Aage. "Coenzyme Q 10". JACC: Heart Failure 3, n.º 3 (março de 2015): 270–71. http://dx.doi.org/10.1016/j.jchf.2014.12.006.

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4

Comhair, Suzy A. A., Deepa Grandon, Anam Khan, Renliang Zhang, Stanley L. Hazen e Serpil C. Erzurum. "Coenzyme Q in Asthma". American Journal of Respiratory and Critical Care Medicine 191, n.º 11 (junho de 2015): 1336–38. http://dx.doi.org/10.1164/rccm.201412-2259le.

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5

Morré, D. James, e Dorothy M. Morré. "Non-mitochondrial coenzyme Q". BioFactors 37, n.º 5 (14 de junho de 2011): 355–60. http://dx.doi.org/10.1002/biof.156.

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6

Finsterer, Josef, e Sinda Zarrouk-Mahjoub. "Causes of low muscle coenzyme-Q levels beyond primary coenzyme-Q-deficiency". Molecular Genetics and Metabolism Reports 15 (junho de 2018): 96–97. http://dx.doi.org/10.1016/j.ymgmr.2018.03.006.

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7

Enriquez, José Antonio, e Giorgio Lenaz. "Coenzyme Q and the Respiratory Chain: Coenzyme Q Pool and Mitochondrial Supercomplexes". Molecular Syndromology 5, n.º 3-4 (2014): 119–40. http://dx.doi.org/10.1159/000363364.

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8

Arroyo, Antonio, Carlos Santos-Ocaña, Macarena Ruiz-Ferrer, Sergio Padilla, Ángela Gavilán, Juan C. Rodríguez-Aguilera e Plácido Navas. "Coenzyme Q is irreplaceable by demethoxy-coenzyme Q in plasma membrane ofCaenorhabditis elegans". FEBS Letters 580, n.º 7 (20 de fevereiro de 2006): 1740–46. http://dx.doi.org/10.1016/j.febslet.2006.02.025.

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9

Beyer, Robert E. "An analysis of the role of coenzyme Q in free radical generation and as an antioxidant". Biochemistry and Cell Biology 70, n.º 6 (1 de junho de 1992): 390–403. http://dx.doi.org/10.1139/o92-061.

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The vital role of coenzyme Q in mitochondrial electron transfer and its regulation, and in energy conservation, is well established. However, the role of coenzyme Q in free oxyradical formation and as an antioxidant remains controversial. Demonstration of the existence of the semiquinone form of coenzyme Q during electron transport, coupled with recent evidence that hydrogen peroxide (but not molecular oxygen) may act as an oxidant of the semiquinone, suggests that the highly reactive OH∙ radical may be formed from the semiquinone. On the other hand, data exist implicating the Fe–S species as the source of electron transfer chain, free radical production. Additional data exist suggesting instead that the unpaired electron of the coenzyme Q semiquinone most likely dismutates superoxide radicals. These concepts and those arising from observations at several levels of organization including subcellular systems, intact animals, and human subjects in the clinical setting, supporting the concept of reduced coenzyme Q as an antioxidant, will be presented. The results of recent studies on the interaction between the two-electron quinone reductase – DT diaphorase and coenzyme Q10 will be presented. The possibility that superoxide dismutase may interact with reduced coenzyme Q, in conjunction with DT diaphorase inhibiting its autoxidation, will be described. The regulation of cellular coenzyme Q concentrations during oxidative stress accompanying aerobic exercise, resulting in increased protection from free radical damage, will also be presented.Key words: coenzyme Q, ubiquinone, free radicals, lipid peroxidation, antioxidant, DT diaphorase, superoxide dismutase, review.
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10

Liancai, Zhu, Wang Bochu ., Tan Jun . e Luo Min . "Coenzyme Q in Cancer Therapy". International Journal of Cancer Research 2, n.º 3 (15 de junho de 2006): 290–98. http://dx.doi.org/10.3923/ijcr.2006.290.298.

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11

KAWASAKI, T. "Antioxidant Function of Coenzyme Q". Journal of Nutritional Science and Vitaminology 38, Special (1992): 552–55. http://dx.doi.org/10.3177/jnsv.38.special_552.

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12

Trevisson, Eva, Salvatore DiMauro, Placido Navas e Leonardo Salviati. "Coenzyme Q deficiency in muscle". Current Opinion in Neurology 24, n.º 5 (outubro de 2011): 449–56. http://dx.doi.org/10.1097/wco.0b013e32834ab528.

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13

Garrido-Maraver, Juan. "Clinical applications of coenzyme Q₁₀". Frontiers in Bioscience 19, n.º 4 (2014): 619. http://dx.doi.org/10.2741/4231.

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14

Bieri, John G. "UBIQUINONE (COENZYME Q) AND UBICHROMENOL". Nutrition Reviews 21, n.º 5 (27 de abril de 2009): 129–31. http://dx.doi.org/10.1111/j.1753-4887.1963.tb04751.x.

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15

Crane, Frederick L. "The evolution of coenzyme Q". BioFactors 32, n.º 1-4 (2008): 5–11. http://dx.doi.org/10.1002/biof.5520320102.

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16

Bentinger, Magnus, Michael Tekle, Kerstin Brismar, Tadeusz Chojnacki, Ewa Swiezewska e Gustav Dallner. "Stimulation of coenzyme Q synthesis". BioFactors 32, n.º 1-4 (2008): 99–111. http://dx.doi.org/10.1002/biof.5520320112.

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17

Quinzii, Catarina M., e Michio Hirano. "Coenzyme Q and mitochondrial disease". Developmental Disabilities Research Reviews 16, n.º 2 (27 de agosto de 2010): 183–88. http://dx.doi.org/10.1002/ddrr.108.

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18

Roels, Oswald A. "Present Knowledge of Coenzyme Q*". Nutrition Reviews 25, n.º 4 (27 de abril de 2009): 97–100. http://dx.doi.org/10.1111/j.1753-4887.1967.tb05589.x.

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19

Bentinger, Magnus, Michael Tekle e Gustav Dallner. "Coenzyme Q – Biosynthesis and functions". Biochemical and Biophysical Research Communications 396, n.º 1 (maio de 2010): 74–79. http://dx.doi.org/10.1016/j.bbrc.2010.02.147.

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20

Appelkvist, E. L., F. Åberg, Z. Guan, I. Parmryd e G. Dallner. "Regulation of Coenzyme Q biosynthesis". Molecular Aspects of Medicine 15 (janeiro de 1994): s37—s46. http://dx.doi.org/10.1016/0098-2997(94)90011-6.

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21

Dallner, Gustav. "Regulation of coenzyme Q biosynthesis". Chemistry and Physics of Lipids 164 (agosto de 2011): S12. http://dx.doi.org/10.1016/j.chemphyslip.2011.05.048.

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22

Crane, F. L. "New functions for coenzyme Q". Protoplasma 213, n.º 3-4 (setembro de 2000): 127–33. http://dx.doi.org/10.1007/bf01282150.

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23

Galinier, A., A. Carrière, Y. Fernandez, A. M. Bessac, S. Caspar-Bauguil, B. Periquet, M. Comtat, J. P. Thouvenot e L. Casteilla. "Biological validation of coenzyme Q redox state by HPLC-EC measurement: relationship between coenzyme Q redox state and coenzyme Q content in rat tissues". FEBS Letters 578, n.º 1-2 (4 de novembro de 2004): 53–57. http://dx.doi.org/10.1016/j.febslet.2004.10.067.

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24

James, Andrew M., Helena M. Cochemé, Masatoshi Murai, Hideto Miyoshi e Michael P. Murphy. "Complementation of coenzyme Q-deficient yeast by coenzyme Q analogues requires the isoprenoid side chain". FEBS Journal 277, n.º 9 (22 de março de 2010): 2067–82. http://dx.doi.org/10.1111/j.1742-4658.2010.07622.x.

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25

Bentinger, Magnus, Kerstin Brismar e Gustav Dallner. "The antioxidant role of coenzyme Q". Mitochondrion 7 (junho de 2007): S41—S50. http://dx.doi.org/10.1016/j.mito.2007.02.006.

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26

Sohal, Rajindar S., e Michael J. Forster. "Coenzyme Q, oxidative stress and aging". Mitochondrion 7 (junho de 2007): S103—S111. http://dx.doi.org/10.1016/j.mito.2007.03.006.

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27

Crane, Frederick L., e Plácido Navas. "The diversity of coenzyme Q function". Molecular Aspects of Medicine 18 (janeiro de 1997): 1–6. http://dx.doi.org/10.1016/s0098-2997(97)00016-2.

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28

Stefely, Jonathan A., e David J. Pagliarini. "Biochemistry of Mitochondrial Coenzyme Q Biosynthesis". Trends in Biochemical Sciences 42, n.º 10 (outubro de 2017): 824–43. http://dx.doi.org/10.1016/j.tibs.2017.06.008.

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29

Turunen, M., E. Swiezewska, T. Chojnacki, P. Sindelar e G. Dallner. "Regulatory Aspects of Coenzyme Q Metabolism". Free Radical Research 36, n.º 4 (janeiro de 2002): 437–43. http://dx.doi.org/10.1080/10715760290021298.

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30

Bour, Sandy, Maria-Carmen Carmona, Anne Galinier, Sylvie Caspar-Bauguil, Luc Van Gaal, Bart Staels, Luc Pénicaud e Louis Casteilla. "Coenzyme Q as an Antiadipogenic Factor". Antioxidants & Redox Signaling 14, n.º 3 (fevereiro de 2011): 403–13. http://dx.doi.org/10.1089/ars.2010.3350.

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31

Garrido-Maraver, Juan, Mario D. Cordero, Manuel Oropesa-Ávila, Alejandro Fernández Vega, Mario de la Mata, Ana Delgado Pavón, Manuel de Miguel et al. "Coenzyme Q10 Therapy". Molecular Syndromology 5, n.º 3-4 (2014): 187–97. http://dx.doi.org/10.1159/000360101.

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32

Kawamukai, Makoto. "Biosynthesis of coenzyme Q in eukaryotes". Bioscience, Biotechnology, and Biochemistry 80, n.º 1 (17 de julho de 2015): 23–33. http://dx.doi.org/10.1080/09168451.2015.1065172.

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33

Lass, Achim, Linda Kwong e Rajindar S. Sohal. "Mitochondrial coenzyme Q content and aging". BioFactors 9, n.º 2-4 (1999): 199–205. http://dx.doi.org/10.1002/biof.5520090215.

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34

Lipshutz, Bruce H., Gerd Bulow, Fernando Fernandez-Lazaro, Sung-Kyu Kim, Richard Lowe, Paul Mollard e Kirk L. Stevens. "A Convergent Approach to Coenzyme Q". Journal of the American Chemical Society 121, n.º 50 (dezembro de 1999): 11664–73. http://dx.doi.org/10.1021/ja992164p.

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35

Navas, Plácido. "The Way to Determine Coenzyme Q". Journal of the American College of Cardiology 62, n.º 3 (julho de 2013): 257. http://dx.doi.org/10.1016/j.jacc.2013.02.083.

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36

Landi, Laura, Luciana Cabrini, Diana Fioremtini, Anna Maria Sechi, Giorgio Sartor, Petronio Pasquali e Lanfranco Masotti. "Coenzyme Q-3 as an antioxidant". Cell Biophysics 16, n.º 1-2 (janeiro de 1990): 1–12. http://dx.doi.org/10.1007/bf02989689.

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37

Turunen, Mikael, Jerker Olsson e Gustav Dallner. "Metabolism and function of coenzyme Q". Biochimica et Biophysica Acta (BBA) - Biomembranes 1660, n.º 1-2 (janeiro de 2004): 171–99. http://dx.doi.org/10.1016/j.bbamem.2003.11.012.

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38

Clarke, Catherine F. "New advances in coenzyme Q biosynthesis". Protoplasma 213, n.º 3-4 (setembro de 2000): 134–47. http://dx.doi.org/10.1007/bf01282151.

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39

Nohl, Hans, Andrey V. Kozlov, Katrin Staniek e Lars Gille. "The Multiple Functions of Coenzyme Q". Bioorganic Chemistry 29, n.º 1 (fevereiro de 2001): 1–13. http://dx.doi.org/10.1006/bioo.2000.1193.

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40

Scialo, Filippo, e Alberto Sanz. "Coenzyme Q redox signalling and longevity". Free Radical Biology and Medicine 164 (fevereiro de 2021): 187–205. http://dx.doi.org/10.1016/j.freeradbiomed.2021.01.018.

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41

Kopřiva, Vladimír, Petr Dvořák, Jana Pokorná e Michal Žďárský. "Coenzyme Q 10 – its biochemical and related aspects". Acta Veterinaria Brno 84, n.º 1 (2015): 43–46. http://dx.doi.org/10.2754/avb201585010043.

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This review analyses the findings of biochemical and related pharmacotherapeutical aspects of coenzyme Q10. Its important role in the respiratory chain is presented. Furthermore, the article presents administration of coenzyme Q10 as a supplement within preventative measures in medicine, its pharmacotherapeutical aspects and effects in a number of diseases of various aetiologies. Concurrently, it presents the issue of mutual interactions of coenzyme Q10 and its efficacy in combining supplementation with conservative therapy of selected aetiologies.
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42

Takayasu, Shoji, e Sanae Katori. "Meniere's Disease and Coenzyme Q10 (1)". Practica oto-rhino-laryngologica. Suppl. 1986, Supplement8 (1986): 249–55. http://dx.doi.org/10.5631/jibirinsuppl1986.1986.supplement8_249.

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43

Boreková, M., J. Hojerová, V. Koprda e K. Bauerová. "Nourishing and health benefits of coenzyme Q10". Czech Journal of Food Sciences 26, No. 4 (22 de agosto de 2008): 229–41. http://dx.doi.org/10.17221/1122-cjfs.

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Coenzyme Q<sub>10</sub> is an important mitochondrial redox component and endogenously produced lipid-soluble antioxidant of the human organism. It plays a crucial role in the generation of cellular energy, enhances the immune system, and acts as a free radical scavenger. Ageing, poor eating habits, stress, and infection – they all affect the organism’s ability to provide adequate amounts of CoQ<sub>10</sub>. After the age of about 35, the organism begins to lose the ability to synthesise CoQ<sub>10</sub> from food and its deficiency develops. Many researches suggest that using CoQ<sub>10</sub> supplements alone or in combination with other nutritional supplements may help maintain health of elderly people or treat some of the health problems or diseases. Due to these functions, CoQ<sub>10</sub> finds its application in different commercial branches such as food, cosmetic, or pharmaceutical industries. This review article gives a survey of the history, chemical and physical properties, biochemistry and antioxidant activity of CoQ<sub>10</sub> in the human organism. It discusses levels of CoQ<sub>10</sub> in the organisms of healthy people, stressed people, and patients with various diseases. This paper shows the distribution and contents of two ubiquinones in foods, especially in several kinds of grapes, the benefits of CoQ<sub>10</sub> as nutritional and topical supplements and its therapeutic applications in various diseases.
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44

Ahmad, SyedS. "Coenzyme Q and its role in glaucoma". Saudi Journal of Ophthalmology 34, n.º 1 (2020): 45. http://dx.doi.org/10.4103/1319-4534.301299.

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45

Tran, UyenPhuong C., e Catherine F. Clarke. "Endogenous synthesis of coenzyme Q in eukaryotes". Mitochondrion 7 (junho de 2007): S62—S71. http://dx.doi.org/10.1016/j.mito.2007.03.007.

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46

Obol'nikova, E. A., e A. I. Kozhukhova. "Biological activity of coenzyme Q analogs (review)". Pharmaceutical Chemistry Journal 27, n.º 12 (dezembro de 1993): 826–33. http://dx.doi.org/10.1007/bf00780572.

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47

Sharp, Jacqueline, Samar Farha, Margaret M. Park, Suzy A. Comhair, Erika L. Lundgrin, W. H. Wilson Tang, Robert D. Bongard, Marilyn P. Merker e Serpil C. Erzurum. "Coenzyme Q supplementation in pulmonary arterial hypertension". Redox Biology 2 (2014): 884–91. http://dx.doi.org/10.1016/j.redox.2014.06.010.

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48

Bogeski, Ivan, Rubin Gulaboski, Reinhard Kappl, Valentin Mirceski, Marina Stefova, Jasmina Petreska e Markus Hoth. "Calcium Binding and Transport by Coenzyme Q". Journal of the American Chemical Society 133, n.º 24 (22 de junho de 2011): 9293–303. http://dx.doi.org/10.1021/ja110190t.

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49

Willis, R. A., K. Folkers, J. L. Tucker, C. Q. Ye, L. J. Xia e H. Tamagawa. "Lovastatin decreases coenzyme Q levels in rats." Proceedings of the National Academy of Sciences 87, n.º 22 (1 de novembro de 1990): 8928–30. http://dx.doi.org/10.1073/pnas.87.22.8928.

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50

Folkers, K., P. Langsjoen, R. Willis, P. Richardson, L. J. Xia, C. Q. Ye e H. Tamagawa. "Lovastatin decreases coenzyme Q levels in humans." Proceedings of the National Academy of Sciences 87, n.º 22 (1 de novembro de 1990): 8931–34. http://dx.doi.org/10.1073/pnas.87.22.8931.

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