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Artigos de revistas sobre o tema "CPA"

Autor: Grafiati

Publicado: 4 de junho de 2021

Última modificação: 25 de julho de 2025

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1

Ren, Jiawei, Xinbo Gao, Liming Chen, et al. "Characteristics of the Ciliary Body in Healthy Chinese Subjects Evaluated by Radial and Transverse Imaging of Ultrasound Biometric Microscopy." Journal of Clinical Medicine 11, no. 13 (2022): 3696. http://dx.doi.org/10.3390/jcm11133696.

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Background: The imaging and analysis of the ciliary body (CB) are valuable in many potential clinical applications. This study aims to demonstrate the anatomy characteristics of CB using radial and transverse imaging of ultrasound biometric microscopy (UBM) in healthy Chinese subjects, and to explore the determining factors. Methods: Fifty-four eyes of 30 healthy Chinese subjects were evaluated. Clinical data, including age, body mass index (BMI), intraocular pressure (IOP), axial length (AL), and lens thickness (LT), were collected. Radial and transverse UBM measurements of the ciliary body w

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Iqbal, Nousheen, Muhammad Irfan, Ammar Mushtaq, and Kauser Jabeen. "Underlying Conditions and Clinical Spectrum of Chronic Pulmonary Aspergillosis (CPA): An Experience from a Tertiary Care Hospital in Karachi, Pakistan." Journal of Fungi 6, no. 2 (2020): 41. http://dx.doi.org/10.3390/jof6020041.

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The incidence of chronic pulmonary aspergillosis (CPA) is especially increasing in high tuberculosis (TB) burden countries. Despite a high estimated CPA burden in Pakistan, actual data on CPA are not available. The aim of the current study is to determine the underlying conditions and clinical spectrum of CPA at a tertiary care hospital in Karachi, Pakistan. This is a retrospective chart review study in patients admitted with CPA from January 2012 to December 2017. A total of 67 patients were identified during the study period. Mean age of CPA patients was 45.9 ± 15 years, 44 (65.7%) were male

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Kim, JungHoon, KyungSik Yoon, IkSu Seo, and KyunKyung Lee. "Estimating The Ratio of The CPA Distance to Velocity for Underwater Target using Bearing CPA." Journal of the Institute of Electronics and Information Engineers 53, no. 6 (2016): 146–51. http://dx.doi.org/10.5573/ieie.2016.53.6.146.

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Xu, Zitong, JunFan Fang, Xuaner Xiang, et al. "Electroacupuncture Alleviates Pain-Related Emotion by Upregulating the Expression of NPS and Its Receptor NPSR in the Anterior Cingulate Cortex and Hypothalamus." Evidence-Based Complementary and Alternative Medicine 2020 (February 10, 2020): 1–16. http://dx.doi.org/10.1155/2020/8630368.

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Objective. Electroacupuncture (EA) is reported effective in alleviating pain-related emotion; however, the underlying mechanism of its effects still needs to be elucidated. The NPS-NPSR system has been validated for the involvement in the modulation of analgesia and emotional behavior. Here, we aimed to investigate the role of the NPS-NPSR system in the anterior cingulate cortex (ACC), hypothalamus, and central amygdala (CeA) in the use of EA to relieve affective pain modeled by complete Freund’s adjuvant- (CFA-) evoked conditioned place aversion (C-CPA). Materials and Methods. CFA injection c

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Feser, W., RS Kerdar H. Blode, and R. Reimann. "Formation of DNA-adducts by selected sex steroids in rat liver." Human & Experimental Toxicology 15, no. 7 (1996): 556–62. http://dx.doi.org/10.1177/096032719601500702.

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1 We are reporting investigations into the potential of the steroid hormones chlormadinone acetate (CMA), cyproterone acetate (CPA), ethinylestradiol (EE2) gestodene (GEST), megestrol acetate (MGA), norethis terone acetate (NET-Ac), estradiol (E 2), and progester one (P) to form DNA-adducts in rat liver in vivo. 2 Compound-related DNA-adduct spots were detected in male and female rat liver following CMA, CPA, and MGA using the 32P-postlabeling-technique. Substance- specific DNA-adducts were also observed in male rats after administration of E2. The other compounds showed no DNA-adduct formatio

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Lee, Meng-Rui, Hung-Ling Huang, Li-Ta Keng, et al. "Establishing Aspergillus-Specific IgG Cut-Off Level for Chronic Pulmonary Aspergillosis Diagnosis: Multicenter Prospective Cohort Study." Journal of Fungi 7, no. 6 (2021): 480. http://dx.doi.org/10.3390/jof7060480.

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Objectives: Aspergillus-specific IgG (Asp-IgG) cut-off level in diagnosing chronic pulmonary aspergillosis (CPA) remains unknown. Methods: We prospectively recruited participants with clinical suspicion of CPA in three centers in Taiwan during 2019 June to 2020 August. Serum Aspergillus fumigatus-specific IgG (Asp-IgG) (Phadia, Uppsala, UPPS, Sweden) was examined. Optimal cut-off level was determined by Youden’s index and validated. Results: A total of 373 participants were recruited. In the derivation cohort (n = 262), Asp-IgG had an area under the receiver-operating-characteristic curve (AUC

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González García, Pablo, Julia Fernández-Navarro, Mónica Bru-Arca, et al. "Three-Month Mortality in Nonhaematological Patients with Chronic Pulmonary Aspergillosis: Differences between Subtypes." Journal of Fungi 10, no. 10 (2024): 706. http://dx.doi.org/10.3390/jof10100706.

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Objectives: Chronic pulmonary aspergillosis (CPA) is a fungal lung infection characterised by the slowly progressing destruction of the lung parenchyma and has four main subtypes. The objective of this work was to evaluate the epidemiology of CPA in our area and evaluate the involvement of the different subtypes in mortality. Methods: This was a descriptive longitudinal retrospective study developed in three tertiary hospitals in Spain. Among all patients admitted with a pulmonary aspergillosis diagnosis, we selected those who fulfilled the criteria for chronic aspergillosis according to the c

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Nakatsugawa, Kohei, Hiroshi Kurosaka, Toshihiro Inubushi, et al. "Stage- and tissue-specific effect of cyclophosphamide during tooth development." European Journal of Orthodontics 41, no. 5 (2019): 519–30. http://dx.doi.org/10.1093/ejo/cjz002.

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Summary Objective The aim of this study was to investigate the toxic effect of cyclophosphamide (CPA) in the development of rodent molars. Methods CPA was administered intraperitoneally in postnatal mice between Day 1 and Day 10, and the morphological phenotype was evaluated at Day 26 using micro-computed tomography and histological analysis, including cell proliferation and cell death analyses. Results M3 molars of the mice who received 100 mg/kg CPA treatment at Day 6 or M2 molars who received treatment at Day 1 resulted in tooth agenesis or marked hypoplasia. Histological observation demons

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Rauf, Akeem, Oyelade Akintoye, Ebere Chukwuemeka, and Israel Okolo. "Compressive and flexural strength of cement mortar blended with cassava peel ash and high-range water-reducing (superplasticizing) admixtures." Engineering Today, no. 00 (2024): 34. http://dx.doi.org/10.5937/engtoday2400011r.

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This paper presents the outcome of an experiment carried out by using cassava peel ash (CPA) of varying quantities to partially replace cement in mortar mix and the influence of adding superplasticizer in the mortar mix is further investigated. The experiment was carried out by partially replacing CPA in the range of 0 to 25 percent by weight of cement at 5% intervals. A water binder ratio (w/b) of 0.5 and superplasticizer dosage of 1.5l/100kg were used to produce the blended mortar of mix 1:3. The samples were cured and tested for compression and flexure at 7, 28, and 90 days after demolding.

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Uzunhan, Yurdagül, Hilario Nunes, Florence Jeny, et al. "Chronic pulmonary aspergillosis complicating sarcoidosis." European Respiratory Journal 49, no. 6 (2017): 1602396. http://dx.doi.org/10.1183/13993003.02396-2016.

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Chronic pulmonary aspergillosis (CPA) complicating sarcoidosis (SA) is associated with high mortality, and there is a lack of clarity regarding the relative contributions of SA or CPA.This was a retrospective single-centre study on CPA-SA.In total, 65 patients (44 men), aged 41.4±13.5 and 48.3±11.9 years at the time of SA and CPA diagnoses, respectively, were included between 1980 and 2015. Of these, 64 had fibrocystic SA, most often advanced, with composite physiological index (CPI) >40 (65% of patients) and pulmonary hypertension (PH) (31%), and 41 patients (63%) were treated for SA (cort

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Formisano, Carmen, Felice Senatore, Svetlana Bancheva, Maurizio Bruno, Antonella Maggio, and Sergio Rosselli. "Volatile Components of Centaurea Bracteata and C. Pannonica subsp. Pannonica growing wild in Croatia." Natural Product Communications 5, no. 10 (2010): 1934578X1000501. http://dx.doi.org/10.1177/1934578x1000501027.

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This paper reports on the volatile components of oils from the aerial parts (CBA) and roots (CBR) of Centaurea bracteata Scop. and aerial parts of C. pannonica (Heuffel) Simonkai subsp. pannonica (CPA), two Asteraceae growing wild in Croatia. The volatile components, obtained by hydrodistillation, were determined by GC-MS analysis. The yields (w/w) of the dried oils were 0.10% (CBA), 0.22% (CBR) and 0.09% (CPA), respectively. A total of 91 compounds were identified accounting for 91.1%, 93.3% and 87.9% of the total oil for CBA, CBR and CPA, respectively. All the samples were characterized main

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Karpen, Ingo Oswald, Gerda Gemser, and Giulia Calabretta. "A multilevel consideration of service design conditions." Journal of Service Theory and Practice 27, no. 2 (2017): 384–407. http://dx.doi.org/10.1108/jstp-05-2015-0121.

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Purpose The purpose of this paper is to advance the current understanding of organisational conditions that facilitate service design. Specifically, the focus is on organisational capabilities, interactive practices and individual abilities as units of analysis across service system levels. Grounded in design principles, the paper conceptualises and delineates illustrative service design conditions and introduces a respective service design capability-practice-ability (CPA) portfolio. In doing so, an emerging microfoundations perspective in the context of service design is advanced. Design/met

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Brackmann, Derald E., and Joni K. Doherty. "CPA Melanoma." Otology & Neurotology 28, no. 4 (2007): 529–37. http://dx.doi.org/10.1097/mao.0b013e3180383694.

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Craey, Erine, Fabian Hulpia, Jeroen Spanoghe, et al. "Ex Vivo Feedback Control of Neurotransmission Using a Photocaged Adenosine A1 Receptor Agonist." International Journal of Molecular Sciences 23, no. 16 (2022): 8887. http://dx.doi.org/10.3390/ijms23168887.

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We report the design, synthesis, and validation of the novel compound photocaged N6-cyclopentyladenosine (cCPA) to achieve precisely localized and timed release of the parent adenosine A1 receptor agonist CPA using 405 nm light. Gi protein-coupled A1 receptors (A1Rs) modulate neurotransmission via pre- and post-synaptic routes. The dynamics of the CPA-mediated effect on neurotransmission, characterized by fast activation and slow recovery, make it possible to implement a closed-loop control paradigm. The strength of neurotransmission is monitored as the amplitude of stimulus-evoked local field

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Janapati, Bharath, Anil Jain, and Priya Sharma. "Medical Image of the Month: Pulmonary Aspergillus Overlap Syndrome Presenting with ABPA, Multiple Bilateral Aspergillomas." Southwest Journal of Pulmonary and Critical Care 22, no. 3 (2021): 76–80. http://dx.doi.org/10.13175/swjpcc002-21.

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No abstract available. Article truncated after 150 words. Introduction. Aspergillus is a ubiquitous fungal organism that causes a variety of pulmonary manifestations, both in immune-competent and immune-compromised patients. It can vary from simple colonization, Aspergilloma, ABPA to Chronic Pulmonary Aspergillosis (CPA) and Invasive Pulmonary Aspergillosis (IPA) (1). ABPA is the most frequently recognized manifestation of allergic aspergillosis, caused by the immunological reactions mounted against Asp. fumigatus. Aspergillomas are rounded conglomerates of fungal hyphae, fibrin, mucus and cel

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Hassan, Moustapha, Hanjing Xie, Lars Ståhle, Zuzana Hassan, and Eva Kimby. "Quantitative Pharmacogenetics of Cyclophosphamide in Patients with Hematological Malignancies." Blood 104, no. 11 (2004): 4604. http://dx.doi.org/10.1182/blood.v104.11.4604.4604.

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Abstract A high degree of interindividual variation in cyclophosphamide (CPA) pharmacokinetics was reported in certain cancer patient groups. To better understand the mechanisms underlying the variation in CPA metabolism, the pharmacokinetics of CPA and its active metabolite 4-OH-CPA were estimated in patients with hematological tumors and related to the genotype of CYP2B6, CYP2C9 and CYP2C19. The influence of liver function on CPA metabolism was also evaluated. Twenty-nine patients with hematological malignancies (MM, ALL or NHL) treated with a conventional CPA dose (1 g/m²) were recruited to

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Franco, A. A., M. H. Kothary, G. Gopinath, et al. "Cpa, the Outer Membrane Protease ofCronobacter sakazakii, Activates Plasminogen and Mediates Resistance to Serum Bactericidal Activity." Infection and Immunity 79, no. 4 (2011): 1578–87. http://dx.doi.org/10.1128/iai.01165-10.

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ABSTRACTCronobacterspp. are emerging neonatal pathogens in humans, associated with outbreaks of meningitis and sepsis. To cause disease, they must survive in blood and invade the central nervous system by penetrating the blood-brain barrier.C. sakazakiiBAA-894 possesses an ∼131-kb plasmid (pESA3) that encodes an outer membrane protease (Cpa) that has significant identity to proteins that belong to the Pla subfamily of omptins. Members of this subfamily of proteins degrade a number of serum proteins, including circulating complement, providing protection from the complement-dependent serum kill

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Bondo Museka, Nickson, and Faustin Mwilambwe Kalombola. "La création de la Cour Pénale Africaine : défis et perspectives d’une justice alternative à la Cour Pénale internationale." Studia Universitatis Babeș-Bolyai Studia Europaea 68, no. 2 (2023): 5–34. http://dx.doi.org/10.24193/subbeuropaea.2023.2.01.

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The creation of the future African Criminal Court (ACC) was envisaged by the African Union (AU) as the African states’ collective response to the ""politicization"" of the International Criminal Court (ICC). Eight years following its signature, the Maloba Protocol has never obtained the fifteen ratifications required to spearhead the operationalisation of the ACC. This article attempts to address two fundamental questions: - what are the challenges hindering the creation of the CCA? - and how effective will the CCA be in trying Africans for crimes they have committed on their own soil? It reve

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Akram, Waqas, Muhammad Bilal Ejaz, Tauqeer Hussain Mallhi, Syed Azhar bin Syed Sulaiman, and Amer Hayat Khan. "Clinical manifestations, associated risk factors and treatment outcomes of Chronic Pulmonary Aspergillosis (CPA): Experiences from a tertiary care hospital in Lahore, Pakistan." PLOS ONE 16, no. 11 (2021): e0259766. http://dx.doi.org/10.1371/journal.pone.0259766.

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Background Chronic pulmonary aspergillosis (CPA) has a wide spectrum of illnesses depending on the progression of the disease and comorbid conditions. However, there is an inadequacy of investigations regarding clinical, laboratory, risk factor and prognostic data on CPA. The current study is aimed to consider the clinical manifestations, risk factors and outcomes of CPA. Methodology Retrospective records of all patients with a confirmed diagnosis of CPA who sought treatment at Gulab Devi Chest Hospital Lahore, Pakistan from January 2017 to December 2019 were evaluated. Data regarding demograp

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Kemik, Ozgur, Ahu Sarbay Kemik, Aziz Sumer, et al. "Serum procarboxypeptidase A and carboxypeptidase A levels in pancreatıc disease." Human & Experimental Toxicology 31, no. 5 (2011): 447–51. http://dx.doi.org/10.1177/0960327111405864.

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Background and objectives: To determine the serum levels of procarboxypeptidase A (pro-CPA) and carboxypeptidase A (CPA) in patients with acute and chronic pancreatitis and pancreatic cancer. Materials and methods: Serum samples obtained from 96 patients with acute pancreatitis, 101 patients with chronic pancreatitis, 98 patients with pancreatic cancer and 96 control groups were assayed for biochemical parameters and serum pro-CPA and CPA. Results: Serum pro-CPA and CPA levels were significantly higher in acute and in chronic pancreatic cancer patients compared to control group ( p < 0.001)

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Rozaliyani, Anna, Harmi Rosianawati, Diah Handayani, et al. "Chronic Pulmonary Aspergillosis in Post Tuberculosis Patients in Indonesia and the Role of LDBio Aspergillus ICT as Part of the Diagnosis Scheme." Journal of Fungi 6, no. 4 (2020): 318. http://dx.doi.org/10.3390/jof6040318.

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Chronic pulmonary aspergillosis (CPA) is a common sequela of pulmonary tuberculosis (TB). The diagnosis of CPA is difficult and often misdiagnosed as smear-negative TB in endemic settings. Aspergillus IgG detection is the cornerstone of CPA diagnosis. There are a lack of studies on the prevalence of CPA in GeneXpert/smear-negative TB patients in Indonesia, despite a high number of TB cases. This study aims to determine the CPA rate in HIV-negative, GeneXpert-negative patients presenting with symptoms following completion of TB therapy and to evaluate the performance of LDBio Aspergillus immuno

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Jia, Qiong, Hongrui Ren, Shuyin Zhang, Haoyu Yang, Shuaipeng Gao, and Ruiwen Fan. "Preparation and Application of Clostridium perfringens Alpha Toxin Nanobodies." Veterinary Sciences 11, no. 8 (2024): 381. http://dx.doi.org/10.3390/vetsci11080381.

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All subtypes of Clostridium perfringens (C. perfringens) produce the alpha toxin (CPA), which can cause enteritis or enterotoxemia in lambs, cattle, pigs, and horses, as well as traumatic clostridial myonecrosis in humans and animals. CPA acts on cell membranes, ultimately leading to endocytosis and cell death. Therefore, the neutralization of CPA is crucial for the prevention and treatment of diseases caused by C. perfringens. In this study, utilizing CPA as an antigen, a nanobody (CPA-VHH) with a half-life of 2.9 h, an affinity constant (KD) of 0.9 nmol/L, and good stability below 60 °C was

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Ostry, V., J. Toman, Y. Grosse, and F. Malir. "Cyclopiazonic acid: 50th anniversary of its discovery." World Mycotoxin Journal 11, no. 1 (2018): 135–48. http://dx.doi.org/10.3920/wmj2017.2243.

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In 1968, the mycotoxin cyclopiazonic acid (CPA) was first discovered and characterised as a chemical substance. Within the following five decades, much has been learned from the results of CPA research. CPA is produced by several Penicillium species (P. griseofulvum, P. camemberti, P. commune, P. dipodomyicola) and Aspergillus species (A. flavus, A. oryzae and A. tamarii). It is widespread on naturally contaminated agricultural raw materials. CPA has been reported to occur in food commodities (e.g. oilseeds, nuts, cereals, dried figs, milk, cheese and meat products) and to possess toxicologica

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Page, Iain D., Rosemary Byanyima, Sharath Hosmane, et al. "Chronic pulmonary aspergillosis commonly complicates treated pulmonary tuberculosis with residual cavitation." European Respiratory Journal 53, no. 3 (2019): 1801184. http://dx.doi.org/10.1183/13993003.01184-2018.

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Chronic pulmonary aspergillosis (CPA) complicates treated pulmonary tuberculosis (TB), with high 5-year mortality. We measured CPA prevalence in this group.398 Ugandans with treated pulmonary TB underwent clinical assessment, chest radiography and Aspergillus-specific IgG measurement. 285 were resurveyed 2 years later, including computed tomography of the thorax in 73 with suspected CPA. CPA was diagnosed in patients without active TB who had raised Aspergillus-specific IgG, radiological features of CPA and chronic cough or haemoptysis.Author-defined CPA was present in 14 (4.9%, 95% CI 2.8–7.9

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McKinney, Christy M., T. Robert Harris, and Raul Caetano. "Reliability of Self-Reported Childhood Physical Abuse by Adults and Factors Predictive of Inconsistent Reporting." Violence and Victims 24, no. 5 (2009): 653–68. http://dx.doi.org/10.1891/0886-6708.24.5.653.

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Little is known about the reliability of self-reported child physical abuse (CPA) or CPA reporting practices. We estimated reliability and prevalence of self-reported CPA and identified factors predictive of inconsistent CPA reporting among 2,256 participants using surveys administered in 1995 and 2000. Reliability of CPA was fair to moderate (κ = 0.41). Using a positive report from either survey, the prevalence of moderate (61.8%) and severe (12.0%) CPA was higher than at either survey alone. Compared to consistent reporters of having experienced CPA, inconsistent reporters were less likely t

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อนุพันธ์, อัครพล, สุรีรัตน์ อารีรักษ์สกุล ก้องโลก та ปุริมปรัชญ์ คณิณพศุตย์. "ผลการจัดการเรียนรู้ตามแนวคิด CPA ที่มีต่อผลสัมฤทธิ์ทางการเรียนและการนำเสนอทางคณิตศาสตร์ เรื่อง เศษส่วน ของนักเรียนชั้นประถมศึกษาปีที่ 3 โรงเรียนสาธิตมหาวิทยาลัยราชภัฏวไลยอลงกรณ์ ในพระบรมราชูปถัมภ์ จังหวัดปทุมธานี". Interdisciplinary Academic and Research Journal 4, № 2 (2024): 767–84. http://dx.doi.org/10.60027/iarj.2024.275227.

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ภูมิหลังและวัตถุประสงค์: กระบวนการคิดทางคณิตศาสตร์จะช่วยให้บุคคลสามารถนำความรู้ทางคณิตศาสตร์ไปใช้ในการแก้ปัญหาต่าง ๆ ได้อย่างมีประสิทธิภาพ ดังนั้นการศึกษาคณิตศาสตร์จึงจำเป็นต้องมีการพัฒนาอย่างต่อเนื่อง การวิจัยครั้งนี้จึงมีวัตถุประสงค์เพื่อ 1) ศึกษาความสัมพันธ์ระหว่างผลสัมฤทธิ์ทางการเรียนคณิตศาสตร์และการนำเสนอทางคณิตศาสตร์ของนักเรียนชั้นประถมศึกษาปีที่ 3 กลุ่มที่ได้รับการจัดกิจกรรมการเรียนรู้ตามแนวคิด CPA และ 2) เปรียบเทียบผลสัมฤทธิ์ทางการเรียนคณิตศาสตร์และการนำเสนอทางคณิตศาสตร์ของนักเรียนชั้นประถมศึกษาปีที่ 3 ระหว่างกลุ่มที่ได้รับการจัดกิจกรรมการเรียนรู้ตามแนวคิด CPA กับกลุ่มที่ได้รับการจัดกิ

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สุขสิงห์, วาริพินทุ์, ชานนท์ จันทรา та ต้องตา สมใจเพ็ง. "ผลการจัดกิจกรรมการเรียนรู้ที่ใช้แนวคิด Concrete Pictorial Abstract (CPA) ร่วมกับเทคนิคการใช้คำถามของ Badham ที่มีต่อมโนทัศน์ทางคณิตศาสตร์ เรื่อง ปริมาตรและความจุของทรงสี่เหลี่ยมมุมฉาก ของนักเรียนชั้นประถมศึกษาปีที่ 5". Interdisciplinary Academic and Research Journal 4, № 6 (2024): 781–800. https://doi.org/10.60027/iarj.2024.278960.

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ภูมิหลังและวัตถุประสงค์: การจัดกิจกรรมการเรียนรู้โดยใช้แนวคิด Concrete Pictorial Abstract (CPA) เป็นการจัดกิจกรรมการเรียนรู้ที่เริ่มจากสิ่งที่เป็นรูปธรรมถ่ายทอดเป็นแผนภาพแล้วเชื่อมโยงสู่สัญลักษณ์ทางคณิตศาสตร์ ซึ่งจะช่วยให้นักเรียนเข้าใจเกี่ยวกับคณิตศาสตร์อย่างเป็นระบบจากรูปธรรมสู่นามธรรมจนนำไปสู่วิธีการแก้ปัญหาได้ เป็นการช่วยพัฒนาความเข้าใจอย่างลึกซึ้งจนเกิดมโนทัศน์ทางคณิตศาสตร์แบบยั่งยืนให้แก่นักเรียน ประกอบกับการใช้คำถามของ Badham เป็นตัวช่วยสำคัญในการกระตุ้นความคิดเชิงคณิตศาสตร์ให้กับนักเรียน และส่งเสริมให้นักเรียนสร้างแนวคิดได้ด้วยตนเอง การวิจัยครั้งนี้มีวัตถุประสงค์เพื่อ 1) ศึกษาแนวทาง กา

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Diaz, G., W. Thompson, and P. Martos. "Stability of cyclopiazonic acid in solution." World Mycotoxin Journal 3, no. 1 (2010): 25–33. http://dx.doi.org/10.3920/wmj2009.1170.

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Cyclopiazonic acid (CPA) is an important mycotoxin given its toxicity and prevalence in foods and feeds. There is tremendous interest in developing analytical methods that include CPA as part of a multi-residue mycotoxin routine, but there appears to be considerable difficulty in analysing it using liquid chromatography with electrospray ionisation tandem mass spectrometry (LC-MS/MS). During the development of a multi-residue method for mycotoxins including CPA, a number of issues were discovered under routine and common analytical conditions that have an impact on the determination of CPA, in

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Saleh, HS, E. Omar, GRA Froemming, and RM Said. "Tocotrienol preserves ovarian function in cyclophosphamide therapy." Human & Experimental Toxicology 34, no. 10 (2015): 946–52. http://dx.doi.org/10.1177/0960327114564793.

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Introduction: Cyclophosphamide (CPA) chemotherapy leads to ovarian failure and infertility. Tocotrienol (T3) is an antioxidant and anti-inflammatory agent. The role of T3 in ovarian protection throughout chemotherapy remains unclear. Aim: To investigate the role of T3 in the preservation of female fertility in CPA treatment. Method: Sixty female mice were divided into five treatment groups, namely, normal saline, corn oil only, T3 only, CPA and CPA + T3. The treatment was given for 30 days, followed by administration of gonadotrophin to induce ovulation. After killing, both ovaries were collec

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Varner, Jex T. "CPA Exam Blues." Critical Perspectives on Accounting 18, no. 7 (2007): 805–6. http://dx.doi.org/10.1016/j.cpa.2006.07.001.

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Ventura, C. I., and R. A. Barrio. "Self-consistent cluster CPA methods and the nested CPA theory." Physica B: Condensed Matter 281-282 (June 2000): 855–56. http://dx.doi.org/10.1016/s0921-4526(99)01160-6.

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Rønberg, Rasmus, Jesper Rømhild Davidsen, Helmut J. F. Salzer, Eva Van Braeckel, Flemming Schønning Rosenvinge, and Christian B. Laursen. "Prevalence of Chronic Pulmonary Aspergillosis in Patients Suspected of Chest Malignancy." Journal of Fungi 8, no. 3 (2022): 297. http://dx.doi.org/10.3390/jof8030297.

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Chronic pulmonary aspergillosis (CPA) is a potentially life-threatening fungal lung infection, and recent research suggests CPA to be more common than previously considered. Although CPA mimics other lung diseases including pulmonary cancer, awareness of this disease entity is still sparse. This study aimed to investigate the prevalence of CPA in a population of patients under suspicion of having lung cancer. We conducted a retrospective cohort study of 1200 patients and manually collected individual health record data from previous cancer examinations, with retrospective CPA status assessment

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Akbari, P., H. Malekinejad, F. Rahmani, A. Rezabakhsh, and J. Fink-Gremmels. "Cyclopiazonic acid attenuates the divalent cations and augments the mRNA level of iNOS in the liver and kidneys of chickens." World Mycotoxin Journal 5, no. 2 (2012): 153–61. http://dx.doi.org/10.3920/wmj2011.1325.

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An investigation was carried out into the occurrence of cyclopiazonic acid (CPA) producing fungi, the level of CPA contamination in chickens' diet, CPA effects on serum levels of divalent cations, on nitric oxide (NO) content and mRNA level of inducible nitric oxide synthase (iNOS) in the liver and kidney of chickens, as well as the cellular and molecular pathways of CPA toxicity. Mycological and HPLC analyses were used to determine the mycobiota and CPA level, respectively. The mycological studies revealed that 34.46 and 23.07% of the isolated fungi were Aspergillus flavus and Penicillium cyc

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SOSA, MARÍA J., JUAN J. CÓRDOBA, CARMEN DÍAZ, et al. "Production of Cyclopiazonic Acid by Penicillium commune Isolated from Dry-Cured Ham on a Meat Extract–Based Substrate." Journal of Food Protection 65, no. 6 (2002): 988–92. http://dx.doi.org/10.4315/0362-028x-65.6.988.

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Penicillium commune, a mold frequently found on dry-cured meat products, is able to synthesize the mycotoxin cyclopiazonic acid (CPA). To evaluate the hazard due to CPA on such foods, the ability of P. commune to grow and produce CPA at water activities (aw) in the range of 0.99 to 0.90 with a meat extract–based medium from 12 to 30°C was determined. CPA was quantified by high-pressure liquid chromatography and mass spectrometry. P. commune was able to grow at every aw and temperature tested. The optimal environmental conditions for growth were 20 to 25°C, at 0.97 to 0.96 aw, but the highest a

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Wang, Huige, Kefei Chen, Tianyu Pan, and Yunlei Zhao. "Practical CCA-Secure Functional Encryptions for Deterministic Functions." Security and Communication Networks 2020 (September 8, 2020): 1–14. http://dx.doi.org/10.1155/2020/8823788.

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Functional encryption (FE) can implement fine-grained control to encrypted plaintext via permitting users to compute only some specified functions on the encrypted plaintext using private keys with respect to those functions. Recently, many FEs were put forward; nonetheless, most of them cannot resist chosen-ciphertext attacks (CCAs), especially for those in the secret-key settings. This changed with the work, i.e., a generic transformation of public-key functional encryption (PK-FE) from chosen-plaintext (CPA) to chosen-ciphertext (CCA), where the underlying schemes are required to have some

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Xiong, Lu, Mengxue Peng, Meng Zhao, and Zhihong Liang. "Truncated Expression of a Carboxypeptidase A from Bovine Improves Its Enzymatic Properties and Detoxification Efficiency of Ochratoxin A." Toxins 12, no. 11 (2020): 680. http://dx.doi.org/10.3390/toxins12110680.

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Ochratoxin A (OTA) is a toxic secondary metabolite produced mainly by Penicillium spp. and Aspergillus spp. and commonly found in foodstuffs and feedstuffs. Carboxypeptidase A (CPA) can hydrolyze OTA into the non-toxic product ochratoxin α, with great potential to realize industrialized production and detoxify OTA in contaminated foods and feeds. This study constructed a P. pastoris expression vector of mature CPA (M-CPA) without propeptide and signal peptide. The results showed that the degradation rate of OTA by M-CPA was up to 93.36%. Its optimum pH was 8, the optimum temperature was 40 °C,

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Urano,, Takashi, Mary W. Trucksess,, Jean Matusik, and Joe W. Dorner. "Liquid Chromatographic Determination of Cyclopiazonic Acid in Corn and Peanuts." Journal of AOAC INTERNATIONAL 75, no. 2 (1992): 319–22. http://dx.doi.org/10.1093/jaoac/75.2.319.

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Abstract A liquid chromatographic (LC) method Is described for the determination of cyclopiazonic acid (CPA) in corn and peanuts. CPA was extracted from the test portion with methanol-2% NaHC03 solution (7 + 3); the extract was defatted with hexane and then acidified. CPA was partitioned into chloroform and applied to a Sep-Pak silica cartridge. CPA was eluted with chloroform-methanol (3 + 1), the solvent was evaporated, and the residue was dissolved In methanol- water (60 + 40). CPA was quantitated by reversed- phase LC with a linear gradient of 0-4mM ZnS04 In methanol-water (85 + 15) and UV

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Imperial, Jessica A., Jess C. Digman, Jheorge Andrea V. Reyes, Ericka V. Salas, and Pastor Judith Valcorza. "Academic and CPALE performance of accountancy graduates' achievement across various academic subjects: Inputs for developmental activity of accountancy students." SDCA Journal of Accountancy 3 (June 30, 2022): 35–43. https://doi.org/10.5281/zenodo.14977398.

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This research was conducted to determine if there is a significant relationship between academic performance and the CPA Licensure Examination performance of the Accountancy graduates who took the CPA Licensure Examination in the years 2016-2019 from colleges and universities within Cavite. The results of the study would help accountancy students and those who aim to enter this field. This research uses chi-square test distribution to identify the relationship between academic and CPA Licensure Examination performance of the respondents. Results showed that there is no significant relationship

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MENDOZA-HUIZAR, L. H., C. H. RIOS-REYES, G. A. ÁLVAREZ-ROMERO, M. E. PALOMAR-PARDAVÉ, and M. T. RAMÍREZ-SILVA. "ELECTROPHILIC AND NUCLEOPHILIC CHEMICAL REACTIVITY OF NEUTRAL AND ANIONIC FORMS OF 4-CPA, 24D-CPA, 34-CPA AND 245T-CPA THROUGH CONCEPTUAL DFT REACTIVITY DESCRIPTORS." Journal of the Chilean Chemical Society 62, no. 1 (2017): 3411–16. http://dx.doi.org/10.4067/s0717-97072017000100022.

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Zheng, Jinpeng, Caihong Lu, Meiyan Yang, et al. "Lung-Targeted Delivery of Cepharanthine by an Erythrocyte-Anchoring Strategy for the Treatment of Acute Lung Injury." Pharmaceutics 14, no. 9 (2022): 1820. http://dx.doi.org/10.3390/pharmaceutics14091820.

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As one of the most frequent complications of critical illness, acute lung injury (ALI) carries a high risk of clinical morbidity and mortality. Cepharanthine (CPA) has significant anti-inflammatory activity, however, due to poor water solubility, low bioavailability, and short half-life, it fails to provide effective clinical management measures. Here, we explored the flexibility of an erythrocyte-anchoring strategy using CPA-encapsulated chitosan-coating nanoparticles (CPA-CNPs) anchored onto circulating erythrocytes for the treatment of ALI. CPA-CNPs adhered to erythrocytes successfully (E-C

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Ito, Yuya, Takahiro Takazono, Yasushi Obase, et al. "Serum Cytokines Usefulness for Understanding the Pathology in Allergic Bronchopulmonary Aspergillosis and Chronic Pulmonary Aspergillosis." Journal of Fungi 8, no. 5 (2022): 436. http://dx.doi.org/10.3390/jof8050436.

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Allergic bronchopulmonary aspergillosis (ABPA) and chronic pulmonary aspergillosis (CPA) are important fungal infections caused by Aspergillus species. An overlap of ABPA and CPA has been reported; therefore, it is critical to determine whether the main pathology is ABPA or CPA and whether antifungals are required. In this study, we investigated whether the serum cytokine profile is useful for understanding the pathology and for differentiating between these diseases. We compared the various serum cytokine levels among healthy subjects and patients diagnosed with asthma, ABPA, or CPA at Nagasa

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Abramo, Francesca, Marta Vascellari, Giada Colzi, et al. "Identification of Histopathological Criteria for the Diagnosis of Canine Cutaneous Progressive Angiomatosis." Veterinary Sciences 9, no. 7 (2022): 340. http://dx.doi.org/10.3390/vetsci9070340.

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The term angiomatosis is used to denote a group of well-known to poorly characterized proliferative vascular entities. In animals, cutaneous progressive angiomatosis (CPA) is a disorder with variable prognosis related to the extension and depth of infiltration of the surrounding tissues by vessels. CPA may share some microscopical features with other vascular proliferations such as low-grade well-differentiated capillaritic hemangiosarcoma (HS), making the diagnosis not always straightforward, especially in small biopsies. The aim of this study is to retrospectively assess the most common diag

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Baluku, J. B., E. Nuwagira, F. Bongomin, and D. W. Denning. "Pulmonary TB and chronic pulmonary aspergillosis: clinical differences and similarities." International Journal of Tuberculosis and Lung Disease 25, no. 7 (2021): 537–46. http://dx.doi.org/10.5588/ijtld.21.0034.

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BACKGROUND: Pulmonary TB (PTB) and chronic pulmonary aspergillosis (CPA) are both progressive and debilitating parenchymal lung diseases with overlapping risk factors, symptomatology and radiological findings that often result in misdiagnosis of either disease.METHODS: We undertook a narrative review approach to describe the clinical and radiological manifestations of CPA and PTB and highlight the salient features that differentiate these two closely related maladies.RESULTS: CPA is a frequent complication of treated PTB. In fact, 15–90% of CPA cases occur in patients with residual lung lesion

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Dalcin, M. O., D. Pianesso, V. C. Silva, et al. "Concentrado proteico de arroz na alimentação do jundiá (Rhamdia quelen)." Arquivo Brasileiro de Medicina Veterinária e Zootecnia 70, no. 1 (2018): 306–14. http://dx.doi.org/10.1590/1678-4162-9730.

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RESUMO O objetivo do presente trabalho foi avaliar a inclusão do concentrado proteico da destilação de etanol obtido de arroz (CPA) na alimentação do jundiá. Trezentos e setenta e cinco peixes foram distribuídos em sistema de recirculação de água com 15 caixas (125L). Foram testadas três dietas (37% PB e 3200kcal/kg de energia digestível), sendo uma controle e duas testando a substituição da proteína da farinha de peixe em 25% (CPA-25%) ou 50% (CPA-50%) pelo CPA. Aos 30 dias, foram avaliadas as variáveis de desempenho, composição corporal e índices somáticos. Os animais submetidos ao tratament

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Rozaliyani, Anna, Sresta Azahra, Findra Setianingrum, and Heri Wibowo. "Clinical Performance of the Aspergillus Western Blot IgG Kit for Serodiagnosis of Chronic Pulmonary Aspergillosis in Post-Tuberculosis Patients." Jurnal Respirologi Indonesia 43, no. 4 (2023): 269–73. http://dx.doi.org/10.36497/jri.v43i4.562.

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Background: Chronic pulmonary aspergillosis (CPA) by Aspergillus spp., which causes slowly progressive destruction to lung parenchyma, is a major complication of pulmonary tuberculosis (TB). Clinical and radiological features of CPA are not typical and might resemble TB. Therefore, detecting Aspergillus-specific IgG is critical for diagnosing CPA.Methods: This cross-sectional study was conducted to evaluate the performance of Aspergillus Western Blot (Asp-WB) IgG kit (LDBio Diagnostics, Lyon, France) for CPA diagnosis in 63 post-TB patients. The analysis was performed by comparing Asp-WB with

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Beşkirli, Ayşe, and İdiris Dağ. "I-CPA: An Improved Carnivorous Plant Algorithm for Solar Photovoltaic Parameter Identification Problem." Biomimetics 8, no. 8 (2023): 569. http://dx.doi.org/10.3390/biomimetics8080569.

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The carnivorous plant algorithm (CPA), which was recently proposed for solving optimization problems, is a population-based optimization algorithm inspired by plants. In this study, the exploitation phase of the CPA was improved with the teaching factor strategy in order to achieve a balance between the exploration and exploitation capabilities of CPA, minimize getting stuck in local minima, and produce more stable results. The improved CPA is called the I-CPA. To test the performance of the proposed I-CPA, it was applied to CEC2017 functions. In addition, the proposed I-CPA was applied to the

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Feyerabend, Thorsten B., Heinz Hausser, Annette Tietz, et al. "Loss of Histochemical Identity in Mast Cells Lacking Carboxypeptidase A." Molecular and Cellular Biology 25, no. 14 (2005): 6199–210. http://dx.doi.org/10.1128/mcb.25.14.6199-6210.2005.

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ABSTRACT Mast cell carboxypeptidase A (Mc-cpa) is a highly conserved secretory granule protease. The onset of expression in mast cell progenitors and lineage specificity suggest an important role for Mc-cpa in mast cells. To address the function of Mc-cpa, we generated Mc-cpa-null mice. Mc-cpa − / − mast cells lacked carboxypeptidase activity, revealing that Mc-cpa is a nonredundant enzyme. While Mc-cpa − / − peritoneal mast cells were ultrastructurally normal and synthesized normal amounts of heparin, they displayed striking histochemical and biochemical hallmarks of immature mast cells. Wild

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Shen, ChangMing, GaoFeng Qiao, Cheng Wang, Feng Jin, and YunZeng Zhang. "Outcomes of surgery for different types of chronic pulmonary aspergillosis: results from a single-center, retrospective cohort study." BMC Pulmonary Medicine 22, no. 1 (2022). http://dx.doi.org/10.1186/s12890-022-01836-z.

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Abstract Background The reported experience of surgical treatment for chronic pulmonary aspergillosis (CPA) mainly focused on simple aspergilloma (SA), few about other types of CPA. The present study aims to evaluate the outcomes of surgical treatment for different types of CPA. Methods We performed a retrospective analysis of 85 patients with CPA who underwent surgery from 2014 to 2020 at Shandong Provincial Chest Hospital. The patients were divided into four types, including SA, chronic cavitary pulmonary aspergillosis (CCPA), chronic fibrosing pulmonary aspergillosis (CFPA), aspergillus nod

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Tabilin, Derrian, Kristen L. Rudd, and Tuppett M. Yates. "Child Maltreatment and Adolescent Dissociative Symptomatology: Moderation by Autonomic Regulation." Child Maltreatment, February 20, 2025. https://doi.org/10.1177/10775595251323218.

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This study drew on the biological sensitivity to context model (Ellis & Boyce, 2008) and polyvagal theory (Porges, 2007) to evaluate the moderating influence of children’s autonomic nervous system (ANS) regulation on pathways from child emotional abuse (CEA) and child physical abuse (CPA) to later dissociative symptoms in adolescence. Participants were 232 youth (50.2% assigned female at birth, 45.9% Latine) who reported on their experiences of CEA and CPA at ages 6, 8, and 10 years. Resting cardiography measures of respiratory sinus arrythmia (RSA) and pre-ejection period (PEP) assessed c

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Garg, Mandeep, Harsimran Bhatia, Inderpaul Sehgal, et al. "The Conundrum of Computed Tomography Findings in Chronic Pulmonary Aspergillosis." Journal of Thoracic Imaging, March 27, 2025. https://doi.org/10.1097/rti.0000000000000828.

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Purpose: To describe the spectrum of computed tomography (CT) findings in various chronic pulmonary aspergillosis (CPA) subtypes. Material and Methods: This retrospective study analyzed the CT scans of consecutively diagnosed CPA cases. Two radiologists independently evaluated the CT findings (both qualitatively and quantitatively) to characterize the lung cavities, intracavitary contents, pericavitary opacities and fibrosis, mediastinal shift, pleural thickening, and underlying structural lung disease. Patients were then classified into CPA subtypes, and between-group differences were assesse

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