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Bibliografias temáticas / Gene mapping / Teses / dissertações

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Teses / dissertações sobre o tema "Gene mapping"

Autor: Grafiati

Publicado: 4 de junho de 2021

Última modificação: 25 de julho de 2025

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1

Audetat, Katherine. "Mapping the mop3 gene." Thesis, The University of Arizona, 2009. http://hdl.handle.net/10150/192275.

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2

Malik, Sajid Perwaiz. "Gene mapping in syndactyly families." [S.l.] : [s.n.], 2005. http://archiv.ub.uni-marburg.de/diss/z2005/0262/.

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3

Backström, Niclas. "Gene Mapping in Ficedula Flycatchers." Doctoral thesis, Uppsala universitet, Institutionen för evolution, genomik och systematik, 2009. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-9513.

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In order to get full understanding of how evolution proceeds in natural settings it is necessary to reveal the genetic basis of the phenotypic traits that play a role for individual fitness in different environments. There are a few possible approaches, most of which stem from traditional mapping efforts in domestic animals and other model species. Here we set the stage for gene mapping in natural populations of birds by producing a large number of anchor markers of broad utility for avian genetical research and use these markers to generate a genetic map of the collared flycatcher (Ficedula a

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4

Söderhäll, Cilla. "Gene mapping of atopic dermatitis /." Stockholm : [Karolinska institutets bibl.], 2001. http://diss.kib.ki.se/2001/91-7349-088-1/.

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5

Setakis, Efrosini. "Gene mapping using DNA pools." Thesis, University of Cambridge, 2004. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.615651.

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6

Bryant, Stephen Paul. "Pedigree analysis and gene mapping." Thesis, Open University, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.390811.

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7

Hernandez-Sanchez, Jules. "Gene mapping using linkage disequilibrium." Thesis, University of Edinburgh, 2002. http://hdl.handle.net/1842/14058.

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The power of QTL detection was studied both empirically and deterministically for several methods. TDT was more powerful than a linkage test, but less powerful than a pure association test. There were no great differences in power between TDTs. One of the TDTs was implemented in BLUP (Best Linear Unbiased Prediction) to study the effect of a candidate gene, the melanocortin 4- receptor (MC4R), on growth, appetite and fatness in pigs. We found significant effects on growth and fatness but not on appetite. TDT uses within families genetic variation. A novel parameter to estimate gene effects usi

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8

Korn, Richard Mervyn. "Mapping sex determining genes and development of techniques for gene mapping in the domestic fowl." Thesis, University of Cambridge, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.624653.

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9

Fasulo, Daniel. "Algorithms for DNA restriction mapping /." Thesis, Connect to this title online; UW restricted, 2000. http://hdl.handle.net/1773/7020.

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10

Tell, Désirée von. "Welander distal myopathy : gene mapping and analysis of candidate genes /." Stockholm, 2004. http://diss.kib.ki.se/2003/91-7349-764-9.

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11

Li, Li. "Disease Gene Mapping in General Pedigrees." NCSU, 2004. http://www.lib.ncsu.edu/theses/available/etd-10212004-142157/.

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Disease gene mapping is one of the main focuses of genetic epidemiology and statistical genetics. This dissertation explores some methods and algorithms in this area, especially in pedigrees. The first chapter gives an introduction to human genetics and disease gene mapping. Existing linkage and association methods are introduced and compared. Probabilities of genotypic data from multiple linked marker loci on related individuals are used as likelihoods of gene locations for gene-mapping, or as likelihoods of other parameters of interest in human genetics. With the recent development in geneti

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12

He, Bing. "Susceptibility gene mapping in multiple sclerosis /." Stockholm, 1998. http://diss.kib.ki.se/search/diss.se.cfm?19980608he.

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13

Parts, Leopold. "Genetic mapping of cellular traits." Thesis, University of Cambridge, 2011. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.609665.

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14

Slape, Christopher Ian. "Molecular characterisation of translocations involving chromosome band 1p36 in acute myeloid leukaemia." Title page, table of contents and abstract only, 2002. http://web4.library.adelaide.edu.au/theses/09PH/09phs6313.pdf.

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"October 2002" Bibliography: leaves 159-198. This thesis describes the mapping of the breakpoints of three different chromosome rearrangements, all involving 1p36, in acute myeloid leukaemia (AML) patients, and an investigation into the molecular outcomes of these rearrangements.

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15

Mumey, Brendan Marshall. "Some computational problems from genomic mapping /." Thesis, Connect to this title online; UW restricted, 1997. http://hdl.handle.net/1773/6932.

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16

Gill, Clare Alexandra. "Use of an ovine bacterial artificial chromosome library for the study of Bovidae genomes." Title page, table of contents and abstract only, 1999. http://web4.library.adelaide.edu.au/theses/09ANP/09anpg475.pdf.

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17

Kalous, Jay Robert. "Candidate gene association mapping in spring wheat." Thesis, Montana State University, 2011. http://etd.lib.montana.edu/etd/2011/kalous/KalousJ0511.pdf.

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Association mapping (AM) is a form of quantitative trait locus (QTL) mapping that utilizes a collection of germplasm rather than a structured mapping population. Marker/trait associations are made through the application of a mixed-effects model that corrects for population stratification. The objective of this study was to evaluate the application of association mapping on a selection of elite spring wheat cultivars. We tested marker/trait associations for known "perfect" markers and markers identified as controlling traits of interest through traditional bi-parental mapping. We als

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18

Melville, Scott Andrew Biotechnology &amp Biomolecular Sciences Faculty of Science UNSW. "Disease gene mapping in border collie dogs." Awarded by:University of New South Wales. School of Biotechnology and Biomolecular Sciences, 2006. http://handle.unsw.edu.au/1959.4/25511.

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Pedigree dog breeds are genetically isolated and inbred populations with characteristics specific to each breed. Some breeds carry genetic diseases which affect the health of the animals, but may also serve as a valuable model to identify genes involved in human disease. In the Border Collie breed in Australia, the identification of two disease genes would enable breeders to DNA test their animals and prevent future cases. Over 530 samples were collected to identify the genes responsible for these diseases through linkage mapping and candidate gene approaches. Collie Eye Anomaly (CEA) defines

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19

Li, Jingyi. "Gene Mapping of Morphological Traits in Chickens." Diss., Virginia Tech, 2017. http://hdl.handle.net/10919/85397.

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Chickens exhibit considerable variation in morphological traits, with some populations having undergone intensive selection for uniqueness and uniformity. These populations are a source of experimental material to study the genetics of morphological traits. An important first step in such studies is to map the genes and the causal mutations that influence these traits. This research focused on gene mapping of 12 morphological traits including 4 intra-feather color patterns (Pattern, Columbian, Melanotic, and mottling), 2 inter-feather color patterns (Blue and chocolate), 2 forms of feathered-l

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20

Hoffman, Lori A. "Disease Gene Mapping Under The Coalescent Model." The Ohio State University, 2010. http://rave.ohiolink.edu/etdc/view?acc_num=osu1282058674.

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21

Duran, Alonso Maria Beatriz. "Genetic mapping of the rat agu gene." Thesis, University of Glasgow, 1997. http://theses.gla.ac.uk/39021/.

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In 1993, a mutant strain, AS/AGU arose spontaneously in an enclosed colony of the Albino Swiss (AS) strain of rat. AS/AGU animals exhibit a set of locomotor abnormalities. They display a general instability and whole body tremor, are slow at initiating movement, show reductions in purposeful action, and perform poorly at locomotor tests such as mid-air righting. L-dopa administration or fetal midbrain transplants reverse the majority of the symptoms, resembling the observations made on Parkinson's disease patients. These features make the AS/AGU strain a useful model for movement disorders due

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22

Guo, Wei. "Some topics of statistical methods in gene mapping." Click to view the E-thesis via HKUTO, 2006. http://sunzi.lib.hku.hk/hkuto/record/B36873688.

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23

Wang, Min. "Fine mapping and candidate gene analysis of murine lung tumor susceptibility genes." Connect to this title online, 2003. http://rave.ohiolink.edu/etdc/view?acc%5Fnum=osu1054682174.

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Thesis (Ph. D.)--Ohio State University, 2003.<br>Title from first page of PDF file. Document formatted into pages; contains xvi, 150 p.; also includes graphics (some col.) Includes bibliographical references (p. 129-150). Available online via OhioLINK's ETD Center

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24

Hinkley, Craig S. (Craig Steven). "Gene Dosage Study on Human Chromosome 22." Thesis, North Texas State University, 1986. https://digital.library.unt.edu/ark:/67531/metadc500617/.

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A gene dosage study was conducted on a rare complete trisomy 22 human fibroblast cell line utilizing three lysosomal enzymes, ∝-iduronidase, ∝-galactosidase B, and arylsulfatase A, whose genes are located on chromosome 22 and two control enzymes, ,β-hexosaminidase A and -- fucosidase, with genes not on chromosome 22. A gene dosage effect was clearly demonstrated for an early passage number of the fibroblasts; however, later passage numbers gave inconclusive results. This study suggests that gene dosage studies must be carefully designed to be conducted only on early, matched passage number cel

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25

Lee, Jun Heon. "Characterising and mapping porcine endogenous retroviruses." Connect to full text, 2000. http://hdl.handle.net/2123/366.

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Thesis (Ph. D.)--University of Sydney, 2000.<br>Includes tables. Title from title screen (viewed Apr. 22, 2008). Submitted in fulfilment of the requirements for the degree of Doctor of Philosophy to the Dept. of Animal Science, Faculty of Agriculture. Includes bibliography. Also available in print form.

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26

Sieberts, Solveig K. "Joint relationship inference from three or more individuals in the presence of genotyping error /." Thesis, Connect to this title online; UW restricted, 2003. http://hdl.handle.net/1773/8970.

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27

Kwan, Sheung-him. "Statistical methods and analyses in human gene mapping." Click to view the E-thesis via HKUTO, 2009. http://sunzi.lib.hku.hk/hkuto/record/B43759117.

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28

Black, Graeme. "The mapping of X-linked ophthalmic disease." Thesis, University of Oxford, 1994. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.358590.

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29

Wang, Luping. "Physical Mapping of Human Transfer RNA Gene Clusters." Thesis, University of North Texas, 1989. https://digital.library.unt.edu/ark:/67531/metadc500957/.

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Two plaque-pure phage lambda clones designated as λhtX-l and λhtX-2 that hybridized to unfractionated bovine liver tRNA were isolated from a human X chromosome-specific library. The λDNAs were characterized by restriction mapping and Southern blot hybridization techniques. The human DNA segment in λhtX-l contains five or more presumptive tRNA genes and at least one Alu family member. The 19-kilobase human DNA insert in λhtX-2 contains two or more presumptive tRNA genes and at least three Alu family members. Another human genomic clone designated λhVKV7 hybridized to mammalian valine tRNA IAC.

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30

De, Poli Emma. "The gene mapping of Senegalese sole (S. senegalensis)." Master's thesis, Alma Mater Studiorum - Università di Bologna, 2018. http://amslaurea.unibo.it/15863/.

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The Senegalese sole (S. senegalensis) is a common flatfish, distributed over the eastern Atlantic coast from the Northern part of Senegal. Senegalese sole aquaculture has aroused great interest in the marine aquaculture in Spain and Portugal because of its relatively rapid growth rate, but it presents limits due to the poor reproduction of captive breeders in many facilities. In fact gonad development during sexual maturation results in major growth reduction, and increased susceptibility to diseases (Felip et al., 2006). Senegalese sole has 42 chromosomes and an XX/XY chromosome system for se

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31

Nicholson, Sharon Joycelyn. "Mapping of Loa : a mouse motor deficit gene." Thesis, Imperial College London, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.344089.

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32

Durrant, Caroline. "Haplotype clustering methods : application to disease gene mapping." Thesis, University of Oxford, 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.432561.

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33

方頌恩 and Chung-yan Gardian Fong. "Electro-clinical study and gene mapping of epilepsies." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2002. http://hub.hku.hk/bib/B31981781.

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34

Kwan, Sheung-him, and 關尚謙. "Statistical methods and analyses in human gene mapping." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2009. http://hub.hku.hk/bib/B43759117.

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35

Nebbali, M. "Human gene mapping using the polymerase chain reaction." Thesis, University of Nottingham, 1992. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.317395.

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36

Baird, Nathan Alder. "Hypoxic gene regulation and high-throughput genetic mapping. /." Connect to title online (ProQuest), 2008. http://proquest.umi.com/pqdweb?did=1525703731&sid=1&Fmt=2&clientId=11238&RQT=309&VName=PQD.

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Thesis (Ph. D.)--University of Oregon, 2008.<br>Typescript. Includes vita and abstract. Includes bibliographical references (leaves 45-52). Also available online in ProQuest, free to University of Oregon users.

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37

Fong, Chung-yan Gardian. "Electro-clinical study and gene mapping of epilepsies." Hong Kong : University of Hong Kong, 2002. http://sunzi.lib.hku.hk/hkuto/record.jsp?B24463826.

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38

Baird, Nathan Alder 1979. "Hypoxic gene regulation and high-throughput genetic mapping." Thesis, University of Oregon, 2008. http://hdl.handle.net/1794/7505.

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xi, 52 p. ; ill. (some col.) A print copy of this title is available through the UO Libraries under the call number: SCIENCE QH445.2 .B35 2008<br>Activation of Heat shock proteins (Hsps) is critical to adaptation to low oxygen levels (hypoxia) and enduring the oxidative stress of reoxygenation. Hsps are known to be regulated by Heat shock factor (Hsf), but my results demonstrate an unexpected regulatory link between the oxygen sensing and heat shock pathways. Hsf transcription is upregulated during hypoxia due to direct binding by Hypoxia-inducible Factor-1 (HIF-1) to HIF-1 response elem

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39

Dash, D. P. "Mapping of a gene causing cataract and keratoconus and analysis of candidate genes." Thesis, Queen's University Belfast, 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.419498.

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40

Maher, Bridget Helen. "Identification of X-Linked Genes in Migraine: Fine Mapping and Candidate Gene Studies." Thesis, Griffith University, 2012. http://hdl.handle.net/10072/367770.

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Migraine is a painful temporarily incapacitating disorder that affects an estimated 12% of the general population including 18% of adult women and 6% of adult men. The disorder involves two main subtypes termed migraine with or without aura (MA and MO respectively). Migraine can present with a variety of symptoms that vary between individuals and between episodes experienced by a single individual. This disorder causes significant social and economic burden and alarmingly is often poorly treated. A direct cause of this is a lack of understanding of the underlying pathology of migraine. Migrain

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41

Sugar, Robert. "Genome analysis in three dimensions : functional analysis of Hi-C derived datasets." Thesis, University of Cambridge, 2015. https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.708667.

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42

Li, Miaoxin. "Development of a bioinformatics and statistical framework to integrate biological resources for genome-wide genetic mapping and its applications." Click to view the E-thesis via HKUTO, 2009. http://sunzi.lib.hku.hk/hkuto/record/B43572030.

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43

Neves, Pereira Maria de Lurdes Marques. "A Gene for Autism Identified by Translocation Breakpoint Mapping." Thesis, University of Aberdeen, 2008. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.485663.

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Autistic disorder (AD). is a common form of childhood neurodevelopmental disorder, characterized by severe and sustained impairment of social interaction and social communicative abilities, as well as a markedly restricted repertoire of activities and interests (American Psychiatric Association, 1994). Microscopic chromosomal rearrangements are seen in 3-6% of cases. Submicroscopic copy number variations (CNVs) were recently.identified in 10% patients with sporadic autism. Intriguingly, these were only found in 2% of patients with an affected first-degree relative, and in 1.0% of controls. Sim

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44

Mucklow, Stuart. "Characterization and mapping of the murine sialoadhesin gene, Sn." Thesis, University of Oxford, 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.337593.

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45

Palma, Federica Di. "Analysis and mapping of bovine MHC class I gene." Thesis, University of Reading, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.248145.

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46

Jansen, Suzaan. "Linkage mapping in Haliotis midae using gene-lnked markers." Thesis, Stellenbosch : Stellenbosch University, 2012. http://hdl.handle.net/10019.1/20347.

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Thesis (MSc)--Stellenbosch University, 2012.<br>ENGLISH ABSTRACT: Haliotis midae, or more commonly known as Perlemoen, is an abalone species found along the coast of South Africa. It is the only cultured abalone species in South Africa and has a high demand abroad. Due to its popularity as a seafood delicacy, illegal harvesting has taken its toll on Perlemoen numbers. This increases the need for sustainable farming efforts and efficient implementation of law enforcement practices against poachers. Abalone farms make use of a limited number of broodstock for breeding, so it is necessary to ens

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47

Kibar, Zoha D. "Mapping of Clouston hidrotic ectodermal dysplasia." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1999. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape7/PQDD_0016/NQ55347.pdf.

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48

Apostolou, Sinoula. "Physical mapping of human chromosome 16." Title page, contents and abstract only, 1997. http://web4.library.adelaide.edu.au/theses/09PH/09pha645.pdf.

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49

Craig, Nicola Jane. "Genetic and physical mapping of the rat agu locus." Thesis, University of Glasgow, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.341722.

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50

Sundholm, James, and n/a. "Analysis of Specific Migraine Candidate Genes Mapping to Human Chromosome 1." Griffith University. School of Health Science, 2003. http://www4.gu.edu.au:8080/adt-root/public/adt-QGU20030829.153348.

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Migraine, comprised of migraine with aura (MA) and migraine without aura (MO), is a painful neurovascular disease, affecting approximately 16% of the general population. It is characterised by a wide variety of symptoms including headache, nausea and vomiting, and photo- and phonophobia. The disorder is complex involving not only multiple genes, but also specific environmental factors, which can induce attacks in genetically predisposed individuals. Hyperhomocysteinaemia is a known risk factor for cerebrovascular, peripheral vascular and coronary heart disease. The Methylenetetrahydrofolate Re

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