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1

Huang, Qingqing, Jiarong Xie, and Jayaraman Seetharaman. "Crystal Structure of Schizosaccharomyces pombe Rho1 Reveals Its Evolutionary Relationship with Other Rho GTPases." Biology 11, no. 11 (2022): 1627. http://dx.doi.org/10.3390/biology11111627.

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The Rho protein, a homolog of Ras, is a member of the Ras superfamily of small GTPases. Rho family proteins are involved in cytoskeletal organization, cell mobility, and polarity, and are implicated in cancer morphogenesis. Although Rho homologs from higher-order mammalian organisms are well studied, there are few studies examining Rho proteins in lower-level single-celled organisms. Here, we report on the crystal structure of Rho1 from Schizosaccharomyces pombe (SpRho1) in complex with GDP in the presence of Mg2+ at a 2.78 Å resolution. The overall structure is similar to that of known Rho ho
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Yang, Zuoxi, and Shoubin Dong. "HSRec: Hierarchical self-attention incorporating knowledge graph for sequential recommendation." Journal of Intelligent & Fuzzy Systems 42, no. 4 (2022): 3749–60. http://dx.doi.org/10.3233/jifs-211953.

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Modeling user’s fine-grained preferences and dynamic preference evolution from their chronological behaviors are challenging and crucial for sequential recommendation. In this paper, we develop a Hierarchical Self-Attention Incorporating Knowledge Graph for Sequential Recommendation (HSRec). HSRec models not only the user’s intrinsic preferences but also the user’s external potential interests to capture the user’s fine-grained preferences. Specifically, the intrinsic interest module and potential interest module are designed to capture these two preferences respectively. In the intrinsic inte
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GUO, Jun-Hua, Jiang-Yong WAN, Wu-Yang YUAN, and Jun-Jie LIU. "Collaborative Optimisation of High-Speed Rail Express Line Planning and Freight Flow Allocation Considering Multiple Transportation Modes and Products." Promet - Traffic&Transportation 36, no. 3 (2024): 415–32. http://dx.doi.org/10.7307/ptt.v36i3.531.

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With the development of high-speed railway (HSR) systems, high-speed rail express delivery (HSReD) is currently the growing trend in railway cargo transport. The decisions on line planning and freight flow allocation are two of the main problems for the practical operation of HSReD. This paper focuses on integrating the above issues, considering differentiated transportation modes and products. A collaborative optimisation model is developed to maximise the benefits of freight transport. Numerical experiments are conducted based on the Beijing-Shanghai HSR. The results show that the collaborat
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Tosi, Umberto, Sergio Guadix, Anjile An, et al. "Efficacy and comorbidities of hypofractionated and single-dose radiosurgery for vestibular schwannomas: a systematic review and meta-analysis." Neuro-Oncology Practice 8, no. 4 (2021): 391–404. http://dx.doi.org/10.1093/nop/npab009.

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Abstract Background Vestibular schwannomas (VS) are tumors of the cerebellopontine angle with significant morbidity, causing hearing loss, tinnitus, and trigeminal and facial nerve compromise. An effective alternative to microsurgical resection is stereotactic radiosurgery (SRS), which can be delivered in either single-fraction (SRS) or hypofractionated stereotactic radiotherapy (hSRT) (3-5 treatments) regimens. It remains unclear which fractionation regimen provides superior outcomes. Methods Ovid MEDLINE, EMBASE, CINAHL, and Cochrane Reviews were searched for studies either comparing hSRT wi
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Kollias, Pavlos, Nitin Bharadwaj, Kevin Widener, Ieng Jo, and Karen Johnson. "Scanning ARM Cloud Radars. Part I: Operational Sampling Strategies." Journal of Atmospheric and Oceanic Technology 31, no. 3 (2014): 569–82. http://dx.doi.org/10.1175/jtech-d-13-00044.1.

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Abstract The acquisition of scanning cloud radars by the Atmospheric Radiation Measurement (ARM) program and research institutions around the world generates the need for developing operational scan strategies for cloud radars. Here, the first generation of sampling strategies for the scanning ARM cloud radars (SACRs) is presented. These scan strategies are designed to address the scientific objectives of ARM; however, they introduce an initial framework for operational scanning cloud radars. While the weather community uses scan strategies that are based on a sequence of scans at constant ele
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Ma, Liang-Hua, Guang Li, Hong-Wei Zhang, et al. "Hypofractionated stereotactic radiotherapy with or without whole-brain radiotherapy for patients with newly diagnosed brain metastases from non–small cell lung cancer." Journal of Neurosurgery 117, Special_Suppl (2012): 49–56. http://dx.doi.org/10.3171/2012.7.gks121071.

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Object This study was undertaken to analyze outcomes in patients with newly diagnosed brain metastases from non–small cell lung cancer (NSCLC) who were treated with hypofractionated stereotactic radiotherapy (HSRT) with or without whole-brain radiotherapy (WBRT). Methods One hundred seventy-one patients comprised the study population. Fifty-four patients received HSRT alone, and 117 patients received both HSRT and WBRT. The median survival time (MST) was determined using the Kaplan-Meier method. Recursive Partitioning Analysis (RPA) and Graded Prognostic Assessment (GPA) were also used to eval
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Tosi, Umberto, Sergio Guadix, Anjile An, et al. "RADT-16. HYPOFRACTIONATED RADIOTHERAPY AND STEREOTACTIC RADIOSURGERY FOR VESTIBULAR SCHWANNOMAS: A SYSTEMATIC REVIEW AND META-ANALYSIS." Neuro-Oncology 22, Supplement_2 (2020): ii184—ii185. http://dx.doi.org/10.1093/neuonc/noaa215.769.

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Abstract BACKGROUND Vestibular schwannomas (VS) are tumors of the cerebellopontine angle with significant morbidity, causing hearing loss, tinnitus, and trigeminal and facial nerve compromise. Surgical resection is complex and often results in comorbidities, with radiation therapy being used to achieve tumor control. Both single dose stereotactic radiosurgery (SRS) and, in recent years, hypofractionated stereotactic radiotherapy (hSRT), where a total 18-25 Gy dose is given in approximately 3-5 fractions, have been utilized. It remains unclear, however, how each of these approaches fares compar
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Ji, Chao, Yanke Yao, Jianqiang Duan, and Wenxing Li. "Sustainable Mechanism of the Entrusted Transportation Management Mode on High-Speed Rail and the Impact of COVID-19: A Case Study of the Beijing–Shanghai High-Speed Rail." Sustainability 14, no. 3 (2022): 1171. http://dx.doi.org/10.3390/su14031171.

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The transport management mode fundamentally determines the sustainable development of high-speed rail passenger transport (HSRPT), which was shocked by the COVID-19 pandemic in 2020. In order to study the sustainable development mechanism of HSRPT and the impact of COVID-19, primarily based on the data from the Beijing–Shanghai high-speed rail (HSR) taken from 2018, we adopt system dynamics (SD) to provide a scenario simulation method to examination sustainable operation status of HSRPT under the entrusted transportation management mode (ETMM) by VENSIM, and take into account the following two
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Smith, Catherine, Jason Key, and Michael Anders. "Examination of Clinical Internship Impact on Critical Thinking Utilizing the Health Science Reasoning Test." American Journal of Clinical Pathology 152, Supplement_1 (2019): S99—S100. http://dx.doi.org/10.1093/ajcp/aqz119.002.

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Abstract Introduction The Health Science Reasoning Test (HSRT) is a validated instrument to assess critical thinking skills and is specifically calibrated for trainees in undergraduate and graduate health science educational programs. The objective of this study was to examine the association of scores on the HSRT with clinical internship education in laboratory science students. Methods In March 2019, assessment of clinical reasoning skills by the HSRT was administered to 29 laboratory science students in the following programs: medical laboratory science and cytotechnology. As this was a pre
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Kusumawati, Daniar, Zafran Jamaris, and Titiek Aslianti. "PROFIL PERTUMBUHAN, ENZIMATIS, DAN NUTRISI IKAN BANDENG (Chanos chanos) GENERASI KEDUA (G-2) TERSELEKSI DENGAN MENERAPKAN STANDAR OPERASIONAL PROSEDUR (SOP) PEMELIHARAAN LARVA." Media Akuakultur 12, no. 2 (2017): 55. http://dx.doi.org/10.15578/ma.12.2.2017.55-66.

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Isu nasional menurunnya produksi budidaya ikan bandeng di tambak pantai utara Pulau Jawa didugasebagai akibat rendahnya kualitas benih produk Hatchery Skala Rumah Tangga (HSRT) di Bali, yang secara kontinu merupakan sumber utama pasok benih. Banyak faktor yang mempengaruhi kualitas benih, antara lain kualitas telur dan induk, serta manajemen pemeliharaan induk dan larva. Tujuan penelitian ini adalah untuk mengevaluasi performa pertumbuhan,aktivitas enzim pencernaan dan nutrisi benih ikan bandeng dari HSRT dan generasi kedua (G2) terseleksi yang dipelihara berdasarkan standar operasional prosed
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Eakins, J. S., L. G. Hager, J. W. Leake, R. S. Mason, and R. J. Tanner. "Calibration of the GNU and HSREM neutron survey instruments." Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment 852 (April 2017): 62–72. http://dx.doi.org/10.1016/j.nima.2016.11.052.

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Sivkov, A. V., and V. I. Kirpatovskiy. "Hypothesis about the possible mechanisms of therapeutic action of Serenoa repens hexane extract on the hypertrophied bladder in accordance with the pathogenesis of its dysfunction caused by bladder outlet obstruction." Experimental and Сlinical Urology 16, no. 2 (2023): 16–30. http://dx.doi.org/10.29188/2222-8543-2023-16-2-16-30.

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Introduction. Traditionally it is believed that the therapeutic effect of the hexane extract of Serenoa repens (HSRE) in patients with benign prostatic hyperplasia is realized due to its effect on prostate cells. However, in the literature there is data about the possible HSRE effect not only on the prostate, but also directly on the bladder. This paper summarizes data and analyzes the possible cellular mechanisms of HSRE action on the bladder under the development of infravesical obstruction (bladder outlet obstruction – BOO). Materials and methods. Literature data from the PubMed and eLibrar
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Liu, Jian, Jiapeng Fang, Zongzhe He, Jun Li, and Liyao Dong. "Target site–based resistance to penoxsulam in late watergrass (Echinochloa phyllopogon) from China." Weed Science 67, no. 4 (2019): 380–88. http://dx.doi.org/10.1017/wsc.2019.14.

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AbstractLate watergrass [Echinochloa phyllopogon (Stapf) Koso-Pol.] is one of the most persistent weeds in rice fields and shows resistance to some acetolactate synthase (ALS)-inhibiting herbicides, such as penoxsulam. Previous studies of E. phyllopogon’s herbicide resistance have focused on non–target site resistance mechanisms. In this study, E. phyllopogon populations from Heilong Jiang Province, China, that were possibly resistant to penoxsulam were used to identify the target site–based mechanisms of resistance. Population HSRH-520 showed a 25.4-fold higher resistance to penoxsulam than t
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Musyaffa Rafiqie. "Calculating Depreciation of Fixed Assets Using the Straight Line Method (Case Study in Household Scale Hatchery (HSRT) Grouper Fish in Pasir Putih Village, Bungatan District, Situbondo Regency)." Samakia : Jurnal Ilmu Perikanan 10, no. 2 (2019): 105–13. http://dx.doi.org/10.35316/jsapi.v10i2.530.

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The purpose of the research is to describe, know and understand the value of depreciation fixed assets with Straight line method. At the Household Scale Hatchery (HSRT) grouper fish, village Pasirputih, Bungatan, Situbondo City.
 Qualitative research methods, descriptive type. The data collected is primary and secondary data. Respondents are taken by purposive sampling in which respondents are taken based on certain criteria. To calculate depreciation of fixed assets and their impact on profits, the Straight Line method is used. 
 The size of the larvae is between 2.5 x 2 x 1.3 m to
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15

Xiao, Furen, Alessandra A. Gorgulho, Chun-Shu Lin, et al. "Treatment of Giant Cerebral Arteriovenous Malformation: Hypofractionated Stereotactic Radiation as the First Stage." Neurosurgery 67, no. 5 (2010): 1253–59. http://dx.doi.org/10.1227/neu.0b013e3181efbaef.

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Abstract BACKGROUND: Treatment of giant cerebral arteriovenous malformations (AVMs) remains a challenge. OBJECTIVE: To propose hypofractionated stereotactic radiotherapy (HSRT) as a part of staged treatment, and evaluate its effect by analyzing AVM volume changes. METHODS: From 2001 to 2007, 20 AVMs larger than 5 cm were treated by HSRT and followed up using magnetic resonance imaging. Patients' median age was 34 years (8–61 years). Eleven patients presented with hemorrhage and 9 with seizure. Ten patients had previous embolization and radiosurgery had failed in 4. Thirteen AVMs (65%) were cla
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Fluckey, James D., Esther E. Dupont-Versteegden, Micheal Knox, Dana Gaddy, Per A. Tesch, and Charlotte A. Peterson. "Insulin facilitation of muscle protein synthesis following resistance exercise in hindlimb-suspended rats is independent of a rapamycin-sensitive pathway." American Journal of Physiology-Endocrinology and Metabolism 287, no. 6 (2004): E1070—E1075. http://dx.doi.org/10.1152/ajpendo.00329.2004.

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Hindlimb suspension (HS) results in rapid losses of muscle mass, which may in part be explained by attenuated rates of protein synthesis. Mammalian target of rapamycin (mTOR) regulates protein synthesis and has been implicated as a potential mediator of the muscle mass decrement with HS. This study examined the effect of resistance exercise, a muscle hypertrophy stimulant, on rates of protein synthesis after 4 days of HS in mature male Sprague-Dawley rats. Flywheel resistance exercise (2 sets × 25 repetitions) was conducted on days 2 and 4 of HS (HSRE). Sixteen hours after the last exercise bo
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Martins, Alexandre Duarte, Orlando Fernandes, Ana Pereira, et al. "The Effects of High-Speed Resistance Training on Health Outcomes in Independent Older Adults: A Systematic Review and Meta-Analysis." International Journal of Environmental Research and Public Health 19, no. 9 (2022): 5390. http://dx.doi.org/10.3390/ijerph19095390.

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Human ageing involves several physiological impairments—in particular, a decrease in sensorimotor function and changes in the nervous system reduce muscle strength, power, balance, and functional capacity performance. Preventive strategies are essential to ensure the quality of life of the elderly. High-speed resistance training (HSRT) may be an effective approach to muscle power development in this population, with significant short-term effects on neural adaptations and muscle power production. Therefore, the present study intends to analyze and systematize the studies focused on HSRT interv
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Guan, Yun, Jing Li, Xiu Gong, et al. "Safety and Efficacy of Hypofractionated Stereotactic Radiotherapy with Anlotinib Targeted Therapy for Glioblastoma at the First Recurrence: A Preliminary Report." Brain Sciences 12, no. 4 (2022): 471. http://dx.doi.org/10.3390/brainsci12040471.

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(1) Background: Hypofractionated stereotactic radiotherapy (HSRT) and anti-vascular endothelial growth factor (VEGF) antibodies have been reported to have a promising survival benefit in recent studies. Anlotinib is a new oral VEGF receptor inhibitor. This report describes our experience using HSRT and anlotinib for recurrent glioblastoma (rGBM). (2) Methods: Between December 2019 and June 2020, rGBM patients were retrospectively analysed. Anlotinib was prescribed at 12 mg daily during HSRT. Adjuvant anlotinib was administered d1-14 every 3 weeks. The primary endpoint was the objective respons
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Carpenter, Rob Edwin, Leanne Coyne, Dave Silberman, and Jody Kyoto Takemoto. "Enhanced numeracy skills following team-based learning in United States pharmacy students: a longitudinal cohort study." Journal of Educational Evaluation for Health Professions 19 (October 27, 2022): 29. http://dx.doi.org/10.3352/jeehp.2022.19.29.

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Purpose: The literature suggests that the ability to numerate cannot be fully understood without accounting for the social context in which mathematical activity is represented. Team-based learning (TBL) is an andragogical approach with theoretical links to sociocultural and community-of-practice learning. This study aimed to quantitatively explore the impact of TBL instruction on numeracy development in 2 cohorts of pharmacy students and identify the impact of TBL instruction on numeracy development from a social perspective for healthcare education.Methods: Two cohorts of students were admin
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Benali, R., J. M. Tournier, M. Chevillard, et al. "Tubule formation by human surface respiratory epithelial cells cultured in a three-dimensional collagen lattice." American Journal of Physiology-Lung Cellular and Molecular Physiology 264, no. 2 (1993): L183—L192. http://dx.doi.org/10.1152/ajplung.1993.264.2.l183.

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Human surface respiratory epithelial (HSRE) cells from nasal polyps have been cultured within collagen lattices in a serum-free defined medium. Cell growth observed over a period of 12 days showed a population doubling time of 36 h. Under these culture conditions, we observed a contraction of the lattices. Phase-contrast light microscopy and transmission electron microscopy demonstrated that the HSRE cells formed tubular ductlike structures. Lumens formed by HSRE cells were surrounded by cuboidal-shaped polarized cells with numerous ciliated cells, secretory cells, and undifferentiated cells.
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Aslianti, Titiek, and Afifah Nasukha. "DAMPAK MOLASE TERHADAP PENINGKATAN KUALITAS BENIH BANDENG (Chanos chanos Forskal ) PRODUK HATCHERY SKALA RUMAH TANGGA DI BALI UTARA." Jurnal Ilmu dan Teknologi Kelautan Tropis 11, no. 3 (2019): 751–61. http://dx.doi.org/10.29244/jitkt.v11i3.26385.

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Tidak stabilnya kualitas benih ikan bandeng produk Hatchery Skala Rumah Tangga (HSRT) di Bali Utara berdampak langsung terhadap produksi budidaya yang terus menurun. Mengantisipasi hal tersebut telah dilakukan perbaikan manajemen dalam proses produksi benih. Penelitian ini dilakukan di lima unit HSRT masing-masing menggunakan 3 unit bak beton berkapasitas 6 m3 yang berada di luar ruangan (outdoor). Setiap bak diisi telur bandeng dengan kepadatan 100.000 butir/bak. Penelitian diulang sebanyak 3 siklus, dengan metode pemeliharaan larva berdasar pada SOP dan CPIB Desinfeksi telur menggunakan iodi
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Fontenot, Justin, Gwen Leigh, Cynthia Watson, et al. "Teaching Prelicensure Nursing Students Reasoning in Clinical Experiences: A Pilot Study." Journal of Nursing Education 62, no. 8 (2023): 467–70. http://dx.doi.org/10.3928/01484834-20230612-06.

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Background: Clinical experiences are foundational learning components for prelicensure nursing students. Given the complexities of modern nursing practice in an aging America, clinical educators must teach nursing students to reason when engaging in patient care. Contemporary pedagogy to enhance reasoning relies on case studies and simulation. Specific and standardized methods for clinical education are largely absent in the literature. Method: This pilot study measured the clinical reasoning ability of nursing students using the Health Sciences Reasoning Test (HSRT). Participants completed th
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Nguyen, Eric K., Timothy K. Nguyen, Gabe Boldt, Alexander V. Louie, and Glenn S. Bauman. "Hypofractionated stereotactic radiotherapy for intracranial meningioma: a systematic review." Neuro-Oncology Practice 6, no. 5 (2018): 346–53. http://dx.doi.org/10.1093/nop/npy053.

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Abstract Background The availability of image guidance and intensity modulation has led to the increasing use of hypofractionated stereotactic radiotherapy (hSRT) as an alternative to conventionally fractionated radiotherapy or radiosurgery for intracranial meningiomas (ICMs). As the safety and efficacy of this approach is not well characterized, we conducted a systematic review of the literature to assess the clinical outcomes of hSRT in the setting of ICMs. Methods A systematic review of Medline and EMBASE databases was performed following the Preferred Reporting Items for Systematic Reviews
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Kendler, K. S., S. L. Lönn, H. H. Maes, J. Sundquist, and K. Sundquist. "The etiologic role of genetic and environmental factors in criminal behavior as determined from full- and half-sibling pairs: an evaluation of the validity of the twin method." Psychological Medicine 45, no. 9 (2014): 1873–80. http://dx.doi.org/10.1017/s0033291714002979.

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BackgroundTwin studies have shown that criminal behavior (CB) is influenced by both genetic and shared environmental factors. Could these results be replicated using full-siblings and half-siblings?MethodIn 911 009 full-siblings reared together (FSRT), 41 872 half-siblings reared together (HSRT) and 52 590 half-siblings reared apart (HSRA), CB was assessed from the Swedish Crime Register. Modeling, including testing for age differences and rearing status, was performed using the OpenMx package.ResultsFive sibling models were fitted examining FSRT and HSRT 0–2 years different in age, and both F
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Kotecha, Rupesh, Arjun Sahgal, Muni Rubens, et al. "Stereotactic radiosurgery for non-functioning pituitary adenomas: meta-analysis and International Stereotactic Radiosurgery Society practice opinion." Neuro-Oncology 22, no. 3 (2019): 318–32. http://dx.doi.org/10.1093/neuonc/noz225.

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Abstract Background This systematic review reports on outcomes and toxicities following stereotactic radiosurgery (SRS) for non-functioning pituitary adenomas (NFAs) and presents consensus opinions regarding appropriate patient management. Methods Using the guidelines of the Preferred Reporting Items for Systematic Reviews and Meta-Analyses, a systematic review was performed from articles of ≥10 patients with NFAs published prior to May 2018 from the Medline database using the key words “radiosurgery” and “pituitary” and/or “adenoma.” Weighted random effects models were used to calculate poole
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Soliman, Hany, Sten Myrehaug, Chia-Lin Tseng, et al. "Image-Guided, Linac-Based, Surgical Cavity-Hypofractionated Stereotactic Radiotherapy in 5 Daily Fractions for Brain Metastases." Neurosurgery 85, no. 5 (2019): E860—E869. http://dx.doi.org/10.1093/neuros/nyz162.

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Abstract BACKGROUND Cavity stereotactic radiotherapy has emerged as a standard option following resection of brain metastases. However, the optimal approach with either single-fraction or hypofractionated stereotactic radiotherapy (HSRT) remains a significant question. OBJECTIVE To report outcomes for 5-fraction HSRT to the surgical cavity, based on contouring according to a recently reported international consensus guideline. METHODS Patients treated with cavity HSRT were identified from a prospective institutional database. Local brain control (LC), distant brain failure (DBF), leptomeningea
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Khan, M. A., M. A. Wohab, M. M. Rahman, and M. M. Alam. "Use of high-speed rotary tiller and power tiller operated seeder for onion (Allium cepa L.) cultivation." Archives of Agriculture and Environmental Science 6, no. 3 (2021): 334–40. http://dx.doi.org/10.26832/24566632.2021.0603011.

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A field study was carried out to assess the performance of power tiller operated seeder (PTOS) and to compare the yield, quality, maturity and economic traits of onion under different planting methods at Spices Research Sub-Centre (SRSC), Bangladesh Agricultural Research Institute (BARI), Faridpur, Bangladesh with four planting methods as four treatments: T1) ploughing the main field with high speed rotary tiller (HSRT) + direct seeding with power tiller operated seeder (PTOS), T2) ploughing the main field with HSRT + transplanting of seedlings, T3) ploughing the main field with HSRT + direct
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Su, Guosheng, Yuhao Wang, Zhitao Han, et al. "Wear Characteristics of Cutting Tool in Brittle Removal of a Ductile Meta in High-Speed Machining." Symmetry 13, no. 9 (2021): 1679. http://dx.doi.org/10.3390/sym13091679.

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The contact stress and heating effect between the cutting tool and workpiece in metal machining is symmetrical. However, the symmetry may be destroyed by changes in the workpiece material mechanical properties, such as ductility. The goal of this study is to reveal the wear characteristics of the cutting tool in machining a ductile metal with the cutting speed at which the metal is embrittled by the high-strain-rate-embrittle effect (HSREE). Orthogonal high-speed turning experiments were carried out. Pure iron type DT8 was cut at different cutting speeds, ranging from 1000 m/min to 9000 m/min.
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Kårlund, Anna, Katarina Sulkula, Kati Väkeväinen, and Jenni Korhonen. "High Pressure Processing Has Variable Effects on Protein-Related and Sensory Properties of Cold and Hot Smoked Rainbow Trout." Applied Sciences 13, no. 7 (2023): 4193. http://dx.doi.org/10.3390/app13074193.

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High pressure processing (HPP) is a state-of-the-art food preservation method that can be applied to many types of food items, including fish products. HPP has been found to affect fish protein conformation, with potentially positive effects on protein digestibility, but detrimental effects on sensory quality. In this study, cold and hot smoked rainbow trout samples (CSRT and HSRT, respectively) were treated with 200, 400, and 600 MPa at 4 °C for 3 min and tested for solubility of proteins (SP) and water holding capacity (WHC). Level of proteolysis (LP) was tested in an in vitro digestion mode
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Gutschenritter, Tyler, Vyshak A. Venur, Stephanie E. Combs, et al. "The Judicious Use of Stereotactic Radiosurgery and Hypofractionated Stereotactic Radiotherapy in the Management of Large Brain Metastases." Cancers 13, no. 1 (2020): 70. http://dx.doi.org/10.3390/cancers13010070.

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Brain metastases are the most common intracranial malignant tumor in adults and are a cause of significant morbidity and mortality for cancer patients. Large brain metastases, defined as tumors with a maximum dimension >2 cm, present a unique clinical challenge for the delivery of stereotactic radiosurgery (SRS) as patients often present with neurologic symptoms that require expeditious treatment that must also be balanced against the potential consequences of surgery and radiation therapy—namely, leptomeningeal disease (LMD) and radionecrosis (RN). Hypofractionated stereotactic radiotherap
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Jacquez, G. M., W. Andrew Marcus, Richard J. Aspinall, and Dunrie A. Greiling. "Exposure assessment using high spatial resolution hyperspectral (HSRH) imagery." Journal of Geographical Systems 4, no. 1 (2002): 1–14. http://dx.doi.org/10.1007/s101090100070.

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et al., Sacgaca. "Factors influencing critical thinking skills among nursing students: Reports from a cross-sectional study." International Journal of ADVANCED AND APPLIED SCIENCES 9, no. 11 (2022): 93–98. http://dx.doi.org/10.21833/ijaas.2022.11.011.

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Studying the relationship between critical thinking and academic achievement is of great importance because both are crucial in producing nurses that would deliver quality care and nurses who would be critical thinkers in the midst of constant evolution in the health care delivery system. This study aims to determine the relationship between critical thinking skills and academic achievement among undergraduate nursing students. Further, it aims to determine factors that may influence the critical thinking of students. This study used a descriptive correlational design. It was conducted at the
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Zaman, RU, and MR Islam. "Performance of Lentil as Affected by Reduced Tillage and Mechanical Seeding." SAARC Journal of Agriculture 18, no. 1 (2020): 51–60. http://dx.doi.org/10.3329/sja.v18i1.48381.

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Generally, lentil seeds are sown following the traditional farming practice with 3-4 numbers of ploughing combined with broadcasting method in lentil growing countries. This is time consuming and costly. The objective of this study was to evaluate the lentil performance as affected by different mechanical seeding system as well as seeding device. There were seven different treatments of which two tillage systems like i) broadcasting after4 times tillage (CT) and ii) broadcasting after tillage with two wheeler driven High Speed Rotary Tiller (HSRT), and five direct mechanical seeding systems li
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Franzese, C., P. Navarria, E. Clerici, et al. "P05.50 Hypofractionated stereotactic radiation therapy (HSRT) in skull base meningiomas." Neuro-Oncology 20, suppl_3 (2018): iii314. http://dx.doi.org/10.1093/neuonc/noy139.376.

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Nguyen, Eric K., Gregory R. Pond, Jeffrey N. Greenspoon, Anthony C. Whitton, and Crystal Hann. "Hypofractionated Stereotactic Radiotherapy for the Treatment of Benign Intracranial Meningiomas: Long-Term Safety and Efficacy." Current Oncology 28, no. 5 (2021): 3683–91. http://dx.doi.org/10.3390/curroncol28050314.

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Introduction: Hypofractionated stereotactic radiotherapy (hSRT) has emerged as an alternative to single-fraction stereotactic radiosurgery (SRS) and conventionally fractionated radiotherapy for the treatment of intracranial meningiomas (ICMs). However, there is a need for data showing long-term efficacy and complication rates, particularly for larger tumors in sensitive locations. Methods: A retrospective review was conducted on adult patients with ICMs seen at a tertiary care center. Eligible patients were treated with the CyberKnife platform and had a planned treatment course of 3–5 fraction
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Nguyen, Timothy K., Arjun Sahgal, Jay Detsky, et al. "Predictors of leptomeningeal disease following hypofractionated stereotactic radiotherapy for intact and resected brain metastases." Neuro-Oncology 22, no. 1 (2019): 84–93. http://dx.doi.org/10.1093/neuonc/noz144.

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Abstract Background The objective was to evaluate the risk and predictors of developing leptomeningeal disease (LMD) in patients with brain metastases treated with 5-fraction hypofractionated stereotactic radiotherapy (HSRT). Methods Patients treated with HSRT for intact brain metastases and/or surgical cavities were reviewed from a prospectively maintained database. Radiographic patterns of LMD were classified as focal classical, diffuse classical, focal nodular, and diffuse nodular. Results HSRT was delivered, most commonly 30 Gy in 5 fractions, to 320 intracranial lesions (57% intact and 43
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Santos, Karine, Marco Preussner, Anna Christina Heroven, and Gert Weber. "Crystallization and biochemical characterization of the human spliceosomal Aar2–Prp8RNaseHcomplex." Acta Crystallographica Section F Structural Biology Communications 71, no. 11 (2015): 1421–28. http://dx.doi.org/10.1107/s2053230x15019202.

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In eukaryotes, the removal of nuclear noncoding sequences (pre-mRNA splicing) is catalyzed by the spliceosome, which consists of five ribonucleoprotein particles (U1, U2, U4, U5 and U6 snRNPs, each with a respective snRNA) and a plethora of protein factors that aid spliceosomal maturation, assembly, activation and disassembly. Recently, the U5 snRNP maturation factor Aar2p from baker's yeast has been characterized structurally and biochemically. Aar2p binds to the RNaseH (RH) and Jab1/MPN domains of the highly conserved U5-specific Prp8p, which forms a framework for the spliceosomal catalytic
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Moilanen, Carolina, Tomas Björkqvist, Markus Ovaska, et al. "Influence of strain rate, temperature and fatigue on the radial compression behaviour of Norway spruce." Holzforschung 71, no. 6 (2017): 505–14. http://dx.doi.org/10.1515/hf-2016-0144.

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Abstract A dynamic elastoplastic compression model of Norway spruce for virtual computer optimization of mechanical pulping processes was developed. The empirical wood behaviour was fitted to a Voigt-Kelvin material model, which is based on quasi static compression and high strain rate compression tests (QSCT and HSRT, respectively) of wood at room temperature and at high temperature (80–100°C). The effect of wood fatigue was also included in the model. Wood compression stress-strain curves have an initial linear elastic region, a plateau region and a densification region. The latter was not r
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Clyde, Joseph W., and Alan W. Katz. "Hypofractionated Stereotactic Radiation Therapy for Metastatic Adenocarcinoma ex Goblet Cell Carcinoid of the Appendix: Case Report and Literature Review." Case Reports in Oncology 12, no. 3 (2019): 807–13. http://dx.doi.org/10.1159/000503879.

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Adenocarcinoma ex-goblet carcinoid (ADA ex-GCC) is a rare and aggressive subtype of goblet cell carcinoid, a distinct tumor of the appendix characterized by both neuroendocrine and glandular differentiation. Patients often present with chronic abdominal pain or symptoms of acute appendicitis. Right hemicolectomy is the primary mode of treatment, and prophylactic salpingo-oophorectomy and hysterectomy is recommended in post-menopausal women due to the tumor’s propensity of transcoelemic spread, especially to the ovaries. In this case report, we describe a patient with ADA ex-GCC who was found t
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Sofiati, Sofiati, Ernik Yuliana, and Lina Warlina. "Strategi Pengembangan Usaha Hatchery Skala Rumah Tangga (HSRT) Kerapu Hybrid Cantang (Epinephelus fuscoguttatus >< Epinephelus lanceolatus)." PELAGICUS 2, no. 1 (2021): 1. http://dx.doi.org/10.15578/plgc.v2i1.9334.

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ABSTRAKTingkat kelangsungan hidup benih kerapu hybrid cantang (Epinephelus fuscoguttatus &gt;&lt; Epinephelus lanceolatus) yang dihasilkan di Situbondo adalah ≤10%, sehingga diperlukan upaya untuk meningkatkan tingkat kelangsungan hidup tersebut. Tujuan penelitian adalah menganalisis faktor-faktor yang mempengaruhi hasil produksi dan merumuskan strategi alternatif pengembangan usaha pembenihan kerapu hybrid cantang skala rumah tangga (HSRT). Hasil penelitian menunjukkan faktor-faktor internal dan ekstrenal secara bersama-sama berpengaruh signifikan terhadap hasil produksi pada usaha HSRT kerap
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Loewen, Peter C. "Genetic mapping of katB, a locus that affects catalase 2 levels in Bacillus subtilis." Canadian Journal of Microbiology 35, no. 8 (1989): 807–10. http://dx.doi.org/10.1139/m89-134.

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A locus affecting the synthesis of spore-specific catalase 2 in Bacillus subtilis was mapped using two- and three-factor trans-ductional crosses at 342 °between hsrE and iol. It was named katB. Strains lacking catalase 2 remained sporulation proficient, but blockage of sporulation at stage IV or earlier affected the electrophoretic mobility of the native enzyme.Key words: Bacillus subtilis, catalase 2, katB, sporulation, mapping.
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Mahadevan, Anand, Scott Floyd, Eric Wong, Clark Chen, and Ekkehard Kasper. "Clinical outcome after Hypofractionated Stereotactic Radiotherapy (HSRT) for benign skull base tumors." Computer Aided Surgery 16, no. 3 (2011): 112–20. http://dx.doi.org/10.3109/10929088.2011.565160.

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Khotimah, Fitriyah Husnul, Alimuddin Alimuddin, Dinar Tri Soelistyowati, et al. "POLA PERTUMBUHAN DAN VARIASI GENETIK BERBASIS DNA MIKROSATELIT DARI TIGA POPULASI IKAN BARAMUNDI Lates calcarifer." Jurnal Riset Akuakultur 18, no. 1 (2024): 49. http://dx.doi.org/10.15578/jra.18.1.2023.49-59.

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Benih ikan baramundi Lates calcarifer diperoleh dari pemijahan alami dengan jumlah induk terbatas sehingga variabilitas pertumbuhan dan kelangsungan hidup antar-batch menjadi tinggi. Penelitian dilakukan untuk menganalisis pertumbuhan dan mengevaluasi variasi genetik ikan kakap putih populasi Australia, Situbondo dan Lampung hasil domestikasi dan dibudidaya di hatcheri skala rumah tangga (HSRT). Sebanyak 10 ekor ikan barramundi dari setiap populasi digunakan untuk analisis variabilitas genetik dengan dua lokus mikrosatelit, yaitu Lca21 dan Lca32. Selanjutnya, data mikrosatelit diolah menggunak
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Tabei, Yusuke, Kengo Sato, and Shunsuke Ichi. "RTHP-07. CYBERKNIFE HYPOFRACTIONATED STEREOTACTIC RADIOTHERAPY FOR THE PATIENTS OF RECURRENT GLIOBLASTOMA WITH BEVACIZUMAB TREATMENT FAILURE." Neuro-Oncology 21, Supplement_6 (2019): vi211. http://dx.doi.org/10.1093/neuonc/noz175.880.

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Abstract BACKGROUND The prognosis for patients with recurrent glioblastoma after Bevacizumab (Bev) treatment is extremely poor. No effective treatment has been established. PURPOSE We retrospectively investigated the efficacy and safety of hypofractionated stereotactic radiotherapy with Cyberknife (CK-HSRT) for recurrent glioblastoma after Bev treatment in our institution. METHODS GTV (Gross tumor volume) was set in the FLAIR abnormal high signal area that resulted in the contrast lesion and invasive recurrence, and PTV (Planning target volume) = GTV + 2 mm. As aimed CK dose,30 Gray(Gy) in 5 f
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Keller, A., and N. R. Ramakrishna. "Results of Hypofractionated Stereotactic Radiation Therapy (HSRT) for Large Brain Metastases and Resection Cavities." International Journal of Radiation Oncology*Biology*Physics 102, no. 3 (2018): e271-e272. http://dx.doi.org/10.1016/j.ijrobp.2018.07.878.

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Ahmad, Zubair, Mohammad Ammar, and Noora J. Al-Thani. "Pedagogical Models to Implement Effective STEM Research Experience Programs in High School Students." Education Sciences 11, no. 11 (2021): 743. http://dx.doi.org/10.3390/educsci11110743.

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High school research experience programs (HSREPs) provide opportunities for true science education and expose students to scientific investigations in laboratory settings. Various HSREPs models have been practiced to shape students’ research understandings; however, a systematic comparison of the success, challenges, and opportunities of these HSREPs has not been gauged. This article compares the effectiveness of such science, technology, engineering, and mathematics (STEM) based HSREP models reported in the last two decades. We shortlisted seventeen studies on the most effective HSREPs and id
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Kumar Gupta, Ranjan, Sudatta Banerjee, and Debdip Khan. "APPLICATION OF CLUSTERING TECHNIQUES TO STUDY THE TRAINING PATTERN PROVIDED BY THE DIFFERENT INSTITUTES UNDER HSRT." International Journal of Advanced Research 8, no. 6 (2020): 911–21. http://dx.doi.org/10.21474/ijar01/11171.

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Kumar, Aryavarta M. S., Jonathan Miller, Seth A. Hoffer, et al. "Postoperative hypofractionated stereotactic brain radiation (HSRT) for resected brain metastases: improved local control with higher BED10." Journal of Neuro-Oncology 139, no. 2 (2018): 449–54. http://dx.doi.org/10.1007/s11060-018-2885-6.

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Gomelsky, Boris, Steven D. Mims, Richard J. Onders, and William B. Bean. "Hormonal Sex Reversal and Evidence of Female Homogamety in Black Crappie." North American Journal of Aquaculture 64, no. 1 (2002): 66–69. http://dx.doi.org/10.1577/1548-8454(2002)064<0066:hsraeo>2.0.co;2.

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Wills, Christopher J., and Glenn Borchardt. "Holocene slip rate and earthquake recurrence on the Honey Lake fault zone, northeastern California." Geology 21, no. 9 (1993): 853. http://dx.doi.org/10.1130/0091-7613(1993)021<0853:hsraer>2.3.co;2.

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