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Livros sobre o tema "Human induce pluripotent stem cell"

Autor: Grafiati

Publicado: 14 de março de 2023

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1

Amit, M., e Joseph Itskovitz-Eldor. Atlas of human pluripotent stem cells: Derivation and culturing. New York: Humana Press, 2012.

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2

Sha, Jin, e SpringerLink (Online service), eds. Human Embryonic and Induced Pluripotent Stem Cells: Lineage-Specific Differentiation Protocols. Totowa, NJ: Springer Science+Business Media, LLC, 2012.

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3

Turksen, Kursad, ed. Induced Pluripotent Stem Cells and Human Disease. New York, NY: Springer US, 2022. http://dx.doi.org/10.1007/978-1-0716-2585-9.

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4

Ye, Kaiming, e Sha Jin, eds. Human Embryonic and Induced Pluripotent Stem Cells. Totowa, NJ: Humana Press, 2012. http://dx.doi.org/10.1007/978-1-61779-267-0.

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5

Song, Loujin. Development of Novel Therapeutics for Timothy Syndrome Using Human Induced Pluripotent Stem Cells. [New York, N.Y.?]: [publisher not identified], 2017.

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6

Pluripotent circulations: Putting actor-network theory to work on stem cells in the USA, prior to 2001. Göteborg: Acta Universitatis Gothoburgensis, 2006.

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7

Itskovitz-Eldor, Joseph, e Michal Amit. Atlas of Human Pluripotent Stem Cells: Derivation and Culturing. Humana, 2016.

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8

Itskovitz-Eldor, Joseph, e Michal Amit. Atlas of Human Pluripotent Stem Cells: Derivation and Culturing. Springer, 2011.

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9

Ye, Kaiming, e Sha Jin. Human Embryonic and Induced Pluripotent Stem Cells: Lineage-Specific Differentiation Protocols. Humana Press, 2016.

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10

Nat, Roxana, e Andreas Eigentler. Cell Culture, iPS Cells and Neurodegenerative Diseases. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780190233563.003.0013.

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Somatic reprogramming technology, which enables the conversion of adult human non-neural cells into neurons, has progressed rapidly in recent years. The derivation of patient-specific induced pluripotent stem (iPS) cells has become routine. The inherent broad differentiation potential of iPS cells makes possible the generation of diverse types of human neurons. This constitutes a remarkable step in facilitating the development of more appropriate and comprehensive preclinical human disease models, as well as for high throughput drug screenings and cell therapy. This chapter reviews recent progress in the human iPS cell culture models related to common and rare NDDs, such as Alzheimer’s disease, Parkinson’s disease, Huntington’s disease, amyotrophic lateral sclerosis, spinal muscular atrophy, and degenerative ataxias. It focuses on the pathophysiological features revealed in cell cultures, and the neuronal subtypes most affected in NDDs. The chapter discusses the validity, limitation, and improvements of this system in faithfully and reproducibly recapitulating disease pathology.

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11

Brennand, Kristen. Application of Stem Cells to Understanding Psychiatric Disorders. Editado por Dennis S. Charney, Eric J. Nestler, Pamela Sklar e Joseph D. Buxbaum. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780190681425.003.0005.

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While much has been learned through clinical post-mortem and neuroimaging studies of patients and animal models of autism spectrum disorder (ASD), bipolar disorder (BD) and schizophrenia (SZ), these classical approaches have yet to fully elucidate the interaction of complex genetic risk factors on disease predisposition. The derivation of human induced pluripotent stem cells (hiPSCs) from patients with psychiatric disorders permits the study of the full complement of risk variants (known and unknown) that underlie disease predisposition, precisely in the cell types relevant to disease. The following chapter covers work to date regarding the advancements in the use of hiPSCs to model psychiatric disorders.

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12

Human Pluripotent Stem Cell Derived Organoid Models. Elsevier, 2020. http://dx.doi.org/10.1016/s0091-679x(20)x0006-9.

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13

Spence, J. Human Pluripotent Stem Cell Derived Organoid Models. Elsevier Science & Technology, 2020.

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14

Spence, J. Human Pluripotent Stem Cell Derived Organoid Models. Elsevier Science & Technology Books, 2020.

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15

Turksen, Kursad. Induced Pluripotent Stem Cells and Human Disease: Methods and Protocols. Springer, 2022.

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16

Loring, Jeanne F., Philip H. Schwartz, Suzanne E. Peterson e Robin L. Wesselschmidt. Human Stem Cell Manual: A Laboratory Guide. Elsevier Science & Technology Books, 2011.

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17

Loring, Jeanne F., e Suzanne Peterson. Human Stem Cell Manual: A Laboratory Guide. Elsevier Science & Technology Books, 2012.

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18

Human Stem Cell Manual: A Laboratory Guide. Academic Press, 2007.

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19

Loring, Jeanne F., e Suzanne Peterson. Human Stem Cell Manual: A Laboratory Guide. Elsevier Science & Technology Books, 2018.

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20

Loring, Jeanne F., e Suzanne Peterson. Human Stem Cell Manual: A Laboratory Guide. Elsevier Science & Technology Books, 2022.

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21

Loring, Jeanne F. Human Stem Cell Manual: A Laboratory Guide. Academic Press, 2007.

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22

Loring, Jeanne F., e Suzanne Peterson. Human Stem Cell Manual: A Laboratory Guide. Elsevier Science & Technology Books, 2012.

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23

Drapeau, Elodie, Hala Harony-Nicolas e Jacqueline N. Crawley. Animal and Cellular Models of Pediatric Psychiatric Disorders. Editado por Dennis S. Charney, Eric J. Nestler, Pamela Sklar e Joseph D. Buxbaum. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780190681425.003.0061.

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The study of childhood psychiatric disorders is especially challenging, not only because of the difficulties in obtaining relevant human samples but also because of ethical considerations regarding the ability of children to provide informed consent. Models that can be experimentally manipulated are therefore indispensable to study those disorders. Traditionally, biological psychiatry research has extensively employed animal models and characterizations of rodent behavior. More recently, induced pluripotent stem cells (iPSCs), and induced differentiation of iPSCs into different types of brain cells have offered new alternative strategies to elucidate mechanisms underlying cellular processes. Regardless of how they are created, optimal models should demonstrate face validity, construct validity, and predictive validity to be considered most relevant. This chapter highlights the major animal and cellular models currently used in the research of childhood-onset psychiatric disorders.

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