Bibliografias temáticas / Human neurogenesis

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Literatura científica selecionada sobre o tema "Human neurogenesis"

Autor: Grafiati
Publicado: 16 de novembro de 2024
Última modificação: 31 de julho de 2025

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Artigos de revistas sobre o assunto "Human neurogenesis"

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Snyder, Jason S. "Questioning human neurogenesis." Nature 555, no. 7696 (2018): 315–16. http://dx.doi.org/10.1038/d41586-018-02629-3.

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Murrell, Wayne, Gillian R. Bushell, Jonathon Livesey, et al. "Neurogenesis in adult human." NeuroReport 7, no. 6 (1996): 1189–94. http://dx.doi.org/10.1097/00001756-199604260-00019.

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Liu, He, and Ni Song. "Molecular Mechanism of Adult Neurogenesis and its Association with Human Brain Diseases." Journal of Central Nervous System Disease 8 (January 2016): JCNSD.S32204. http://dx.doi.org/10.4137/jcnsd.s32204.

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Recent advances in neuroscience challenge the old dogma that neurogenesis occurs only during embryonic development. Mounting evidence suggests that functional neurogenesis occurs throughout adulthood. This review article discusses molecular factors that affect adult neurogenesis, including morphogens, growth factors, neurotransmitters, transcription factors, and epigenetic factors. Furthermore, we summarize and compare current evidence of associations between adult neurogenesis and human brain diseases such as Alzheimer's disease, Parkinson's disease, Huntington's disease, and brain tumors.
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Sugano, Hidenori, Madoka Nakajima, Ikuko Ogino, and Hajime Arai. "Neurogenesis in Human Epileptic Hippocampus." Journal of the Japan Epilepsy Society 26, no. 1 (2008): 16–25. http://dx.doi.org/10.3805/jjes.26.16.

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Flor-García, Miguel, Julia Terreros-Roncal, Elena P. Moreno-Jiménez, Jesús Ávila, Alberto Rábano, and María Llorens-Martín. "Unraveling human adult hippocampal neurogenesis." Nature Protocols 15, no. 2 (2020): 668–93. http://dx.doi.org/10.1038/s41596-019-0267-y.

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Lucassen, Paul J., Nicolas Toni, Gerd Kempermann, Jonas Frisen, Fred H. Gage, and Dick F. Swaab. "Limits to human neurogenesis—really?" Molecular Psychiatry 25, no. 10 (2019): 2207–9. http://dx.doi.org/10.1038/s41380-018-0337-5.

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Inta, agos, and Peter Gass. "Is Forebrain Neurogenesis a Potential Repair Mechanism after Stroke?" Journal of Cerebral Blood Flow & Metabolism 35, no. 7 (2015): 1220–21. http://dx.doi.org/10.1038/jcbfm.2015.95.

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The use of adult subventricular zone (SVZ) neurogenesis as brain repair strategy after stroke represents a hot topic in neurologic research. Recent radiocarbon-14 dating has revealed a lack of poststroke neurogenesis in the adult human neocortex; however, adult neurogenesis has been shown to occur, even under physiologic conditions, in the human striatum. Here, these results are contrasted with experimental poststroke neurogenesis in the murine brain. Both in humans and in rodents, the SVZ generates predominantly calretinin (CR)-expressing GABAergic interneurons, which cannot replace the broad
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Kessaris, Nicoletta. "Human cortical interneuron development unraveled." Science 375, no. 6579 (2022): 383–84. http://dx.doi.org/10.1126/science.abn6333.

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Mustafin, Rustam N., and Elza K. Khusnutdinova. "Postnatal neurogenesis in the human brain." Morphology 159, no. 2 (2022): 37–46. http://dx.doi.org/10.17816/1026-3543-2021-159-2-37-46.

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Recently, a lot of data has been gathered which demonstrates neurogenesis in the brain of adult humans. In genetics, findings have been obtained that not only prove, but also elucidate the molecular mechanisms of neurogenesis. In some publications, however, morphology disputes neuronal renewal in adulthood. Therefore, this review presents the modern achievements of epigenetics, morphology, and physiology, which confirm and characterize postnatal neurogenesis in detail. We suggest that the introduction of molecular genetic technologies into morphological studies will be the starting point for t
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Lewis, Sian. "Human olfaction is not neurogenesis-dependent." Nature Reviews Neuroscience 13, no. 7 (2012): 451. http://dx.doi.org/10.1038/nrn3286.

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Teses / dissertações sobre o assunto "Human neurogenesis"

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Andersson, Annika. "Studies on neurogenesis in the adult human brain." Thesis, Södertörn University College, School of Life Sciences, 2010. http://urn.kb.se/resolve?urn=urn:nbn:se:sh:diva-3646.

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<p>Many studies on neurogenesis in adult dentate gyrus (DG) have been performed on rodents and other mammalian species, but only a few on adult human DG.  This study is focusing on neurogenesis in adult human DG. To characterize the birth of cells in DG, the expression of the cell proliferation marker Ki67 was examined using immunohistochemistry. Ki67-positive labelling was indeed observed in the granular cell layer and the molecular layer of dentate gyrus and in the hilus of hippocampus, as well as in the subgranular zone (SGZ). The Ki67 positive nuclei could be divided into three groups, bas
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Yu, Chieh. "Heparan sulfate proteoglycans in human models of Neurogenesis." Thesis, Queensland University of Technology, 2020. https://eprints.qut.edu.au/203960/1/Chieh_Yu_Thesis.pdf.

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This thesis examined cell surface glycoproteins the heparan sulfate proteoglycans, as regulators of the human nervous system and identified a number of potentially novel stem cell targets for use in treating neurological disorders. Due to the poor outcome of current stem cell transplantation therapies for brain injury and neurodegeneration, this project aimed to understand the fundamentals of human neurogenesis with implications in improving stem cell therapy, understanding brain development, and the factors mediating neurodegeneration.
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Komuro, Yutaro. "Altered adult neurogenesis in a mouse model of human tauopathy." Case Western Reserve University School of Graduate Studies / OhioLINK, 2015. http://rave.ohiolink.edu/etdc/view?acc_num=case1434743393.

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Ahmad, Ruhel [Verfasser], and Albrecht [Akademischer Betreuer] Müller. "Neurogenesis from parthenogenetic human embryonic stem cells / Ruhel Ahmad. Betreuer: Albrecht Müller." Würzburg : Universitätsbibliothek der Universität Würzburg, 2013. http://d-nb.info/1031379878/34.

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Wei, Yulei. "Genetic Knowledge-based Artificial Control over Neurogenesis in Human Cells Using Synthetic Transcription Factor Mimics." Kyoto University, 2018. http://hdl.handle.net/2433/232265.

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Garnett, Shaun. "Generating a proteomic profile of neurogenesis, through the use of human foetal neural stem cells." Doctoral thesis, Faculty of Science, 2019. http://hdl.handle.net/11427/31143.

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Introduction Neurogenesis, the development of new neurons, starts soon after the formation of the neural tube and is largely completed by birth. Development of the brain after birth is mainly reliant on the formation of new connections between surviving neurons. However, adult neurogenesis does continue in the subgranular zone of the hippocampus from quiescent adult neural stem cells. Traditionally neural stem cells were cultured as neurospheres, a heterogeneous agglomeration of neural cells at various stages of differentiation. This heterogeneity prevented accurate quantitative analysis. In 2
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Bramwell, Thomas William. "Investigations into the use of human embryonal carcinoma stem cells as a model to study dopaminergic neurogenesis." Thesis, Durham University, 2009. http://etheses.dur.ac.uk/2071/.

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Parkinson's disease in reality arises as a result of a complex series of events, however it is strongly linked to the loss of a specific cellular population of midbrain dopaminergic neurons making it a candidate for stem cell based research. Stem cells can be cultured in vitro and via asymmetric cell division possess the capacity for both self renewal and the production of differentiated derivatives. The use of specific molecules and culture conditions can be applied to promote the differentiation of them towards particular cellular fates, in turn facilitating the possibility of producing enri
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Oikari, Lotta Emilia. "Regulation of human neural stem cell fate determination by proteoglycans." Thesis, Queensland University of Technology, 2017. https://eprints.qut.edu.au/103844/8/Lotta_Emilia_Oikari_Thesis.pdf.

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This thesis investigated how human neural stem cells are regulated, focusing specifically on heparan sulfate proteoglycans, the key proteins of the extracellular space. The findings of this study identified central roles for proteoglycans in mediating neural stem cell events, including self-renewal and differentiation. This research has improved our understanding of human stem cell and human neurogenesis biology and provided novel approaches for the development of improved neural stem cell applications, including using these cells for brain damage therapy.
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GUARNIERI, GIULIA. "Human cholinergic neurons from nucleus basalis of Meynert: a new promising tool to study pathogenetic mechanisms affecting neurogenesis." Doctoral thesis, Università di Siena, 2019. http://hdl.handle.net/11365/1072770.

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The degeneration of basal forebrain cholinergic neurons within the nucleus basalis of Meynert (NBM) is responsible for the cognitive decline in neurodegenerative disorders, including Alzheimer’s disease (AD) and Parkinson’s disease (PD). Indeed, the major therapeutic strategies have been directed toward the cholinergic system. However, no effective therapies exist to contrast NBM cholinergic neuron loss and investigations in the field are strongly restricted by the lack of human models. Thus, the work of this thesis firstly contributed to establish and characterise a novel primary culture of c
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Pigeon, Julien. "The role of NEUROG2 T149 phosphorylation site in the developing human neocortex." Electronic Thesis or Diss., Sorbonne université, 2024. http://www.theses.fr/2024SORUS092.

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Le développement des fonctions cognitives supérieures observée au cours de l'évolution des mammifères, repose sur la capacité des progéniteurs corticaux à augmenter leur production neuronale et ainsi étendre la surface du neocortex. Chez les mammifères dit gyrencéphaliques, où la période de production neuronale est allongée, la régulation du type de division, proliférative ou neurogénique, des progéniteurs corticaux est d'autant plus importante pour garantir l'accumulation de neurones. Dans le télencéphale dorsal, à l'origine du néocortex, c'est l'articulation de la voie de signalisation Notch
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Livros sobre o assunto "Human neurogenesis"

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Winter, Robin M. London dysmorphology database: &, London neurogenetics database. 2nd ed. Oxford University Press, 1998.

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Winter, Robin M. London dysmorphology database. 2nd ed. Oxford University Press, 1996.

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R, Hayden Michael, and Rubinsztein D. C, eds. Analysis of triplet repeat disorders. Bios Scientific Publishers, 1998.

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Sutcliffe, Alastair. Congenital anomalies: Case studies and mechanisms. InTech, 2012.

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D, Wells R., Warren Stephen T, and Sarmiento Marion, eds. Genetic instabilities and hereditary neurological diseases. Academic Press, 1998.

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1946-, Oostra Ben A., ed. Trinucleotide diseases and instability. Springer, 1998.

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Takao, Kumazawa, Kruger Lawrence, and Mizumura Kazue, eds. The polymodal receptor: A gateway to pathological pain. Elsevier, 1996.

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Cryan, John F., and Andreas Reif. Behavioral Neurogenetics. Springer, 2014.

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Cryan, John F., and Andreas Reif. Behavioral Neurogenetics. Springer, 2012.

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Cryan, John F., and Andreas Reif. Behavioral Neurogenetics. Springer London, Limited, 2012.

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Capítulos de livros sobre o assunto "Human neurogenesis"

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Doğanyiğit, Züleyha, and Aslı Okan Oflamaz. "Development of the Hippocampus and Hippocampal Neurogenesis." In The Human Hippocampus. Springer Nature Switzerland, 2025. https://doi.org/10.1007/978-3-031-88907-3_2.

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Bédard, Andréanne, Patrick J. Bernier, and André Parent. "Neurogenesis in Monkey and Human Adult Brain." In Neurogenesis in the Adult Brain II. Springer Japan, 2011. http://dx.doi.org/10.1007/978-4-431-53945-2_1.

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Sachan, Nalani, Mousumi Mutsuddi, and Ashim Mukherjee. "Notch Signaling: From Neurogenesis to Neurodegeneration." In Insights into Human Neurodegeneration: Lessons Learnt from Drosophila. Springer Singapore, 2019. http://dx.doi.org/10.1007/978-981-13-2218-1_7.

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Suzuki, Masatoshi, Jacalyn McHugh, and Narisorn Kitiyanant. "Human Neural Progenitor Cells: Mitotic and Neurogenic Effects of Growth Factors, Neurosteroids, and Excitatory Amino Acids." In Hormones in Neurodegeneration, Neuroprotection, and Neurogenesis. Wiley-VCH Verlag GmbH & Co. KGaA, 2011. http://dx.doi.org/10.1002/9783527633968.ch19.

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Vineyard, Craig M., Stephen J. Verzi, Thomas P. Caudell, Michael L. Bernard, and James B. Aimone. "Adult Neurogenesis: Implications on Human And Computational Decision Making." In Foundations of Augmented Cognition. Springer Berlin Heidelberg, 2013. http://dx.doi.org/10.1007/978-3-642-39454-6_57.

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Ølstørn, Håvard, Morten C. Moe, Mercy Varghese, and Iver A. Langmoen. "Neurogenesis and Potential Use of Stem Cells from Adult Human Brain." In Stem Cells, Human Embryos and Ethics. Springer Netherlands, 2008. http://dx.doi.org/10.1007/978-1-4020-6989-5_4.

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de los Rios, Maria Elizabeth. "Reflections on neurogenetic challenges to human dignity and social doctrine of the Catholic Church." In Interreligious Perspectives on Mind, Genes and the Self. Routledge, 2018. http://dx.doi.org/10.4324/9780429456145-12.

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Bhaduri, Aparna, Madeline G. Andrews, and Arnold R. Kriegstein. "Human neurogenesis." In Patterning and Cell Type Specification in the Developing CNS and PNS. Elsevier, 2020. http://dx.doi.org/10.1016/b978-0-12-814405-3.00029-1.

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"Timespans of Neurogenesis." In Atlas of Human Central Nervous System Development. CRC Press, 2007. http://dx.doi.org/10.1201/9781420003284.ax1.

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Gong, Jing, Jiahui Kang, Minghui Li, Xiao Liu, Jun Yang, and Haiwei Xu. "Applications of Neural Organoids in Neurodevelopment and Regenerative Medicine." In Organoids [Working Title]. IntechOpen, 2022. http://dx.doi.org/10.5772/intechopen.104044.

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Recent advances in stem cell technologies have enabled the application of three-dimensional neural organoids for exploring the mechanisms of neurodevelopment and regenerative medicine. Over the past decade, series of studies have been carried out to investigate the cellular and molecular events of human neurogenesis using animal models, while the species differences between animal models and human being prevent a full understanding of human neurogenesis. Human neural organoids provide a new model system for gaining a more complete understanding of human neural development and their application
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Trabalhos de conferências sobre o assunto "Human neurogenesis"

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Proshchina, Alexandra, Anastasia Kharlamova, Olga Godovalova, Evgeniya Grushetskaya, and Sergey Saveliev. "IMMUNOPHENOTYPIC PROFILES OF NEUROGENESIS IN THE DEVELOPMENT OF THE HUMAN CEREBRAL CORTEX." In XX INTERNATIONAL INTERDISCIPLINARY CONGRESS NEUROSCIENCE FOR MEDICINE AND PSYCHOLOGY. LCC MAKS Press, 2024. http://dx.doi.org/10.29003/m4000.sudak.ns2024-20/230-231.

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Bobkova, Natalia Victorovna, Rimma Alekseevna Poltavtseva, Daria Jurievna Zhdanova, Vladimir Igorevich Kovalev та Alina Vadimovna Chaplygina. "THE EFFECT OF YB-1 PROTEIN IN СHIMERIC MODEL OF ALZHEIMER’S DISEASE". У NEW TECHNOLOGIES IN MEDICINE, BIOLOGY, PHARMACOLOGY AND ECOLOGY. Institute of information technology, 2021. http://dx.doi.org/10.47501/978-5-6044060-1-4.10.

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The paper focuses on the molecular cell interaction of human mesenchymal stromal cells with the hippocampal primary culture of transgenic XFAD mice and the effect of multifunctional YB-1 protein on the memory and state of adult neurogenesis niches in animals with a chi-meric model of Alzheimer's disease. The results suggest the usefulness of a comprehensive use of cell therapy in combination with YB-1 to activate compensatory mechanisms in patients with Alzheimer's disease.
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Yildirim, Murat, Danielle Feldman, Tianyu Wang, et al. "Third harmonic generation imaging of intact human cerebral organoids to assess key components of early neurogenesis in Rett Syndrome (Conference Presentation)." In Multiphoton Microscopy in the Biomedical Sciences XVII, edited by Ammasi Periasamy, Peter T. So, Xiaoliang S. Xie, and Karsten König. SPIE, 2017. http://dx.doi.org/10.1117/12.2256182.

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Porcino, Caterina. "NEUROTROPHINS, TRK-RECEPTORS AND CALCIUM BINDING PROTEIN LOCALIZATION IN MECHANOSENSORY SYSTEMS AND RETINA OF NOTHOBRANCHIUS GUENTHERI." In Dubai International Conference on Research in Life-Science & Healthcare, 22-23 February 2024. Global Research & Development Services, 2024. http://dx.doi.org/10.20319/icrlsh.2024.4243.

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Neurotrophins are growth factors playing a crucial role in the survival, differentiation, development, and plasticity of neurons. They exert their effects by binding to specific receptors (Trks) in the central and peripheral nervous systems, including sensory organs. Calcium-binding proteins (CaBPs) are also present in these systems. They are involved in essential physiological functions related to calcium ions, such as nerve impulse transmission, neurogenesis, synaptic plasticity, and transmission. Further, CaBPs are supposed to be involved in neuron protection. Neurotrophins and CaBPs perfor
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