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Artigos de revistas sobre o tema "Improve the skin hydration"

Autor: Grafiati

Publicado: 7 de junho de 2025

Última modificação: 2 de agosto de 2025

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1

Aarti, Jadhav* Dr. Sadhana Shahi Sejal Bankar Runali Sutar. "The Science of Skin Hydration: Essential Ingredients for Dewy Skin." International Journal of Pharmaceutical Sciences 3, no. 4 (2025): 1505–24. https://doi.org/10.5281/zenodo.15202816.

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Skin hydration refers to the process of maintaining an optimal level of moisture within the skin, which is essential for maintaining its health, elasticity, and overall appearance. Natural Moisturizing Factor (NMF) is the naturally occurring substance in stratum corneum which is responsible for skin hydration. Lamellar arrangement of inter-cellular lipids plays effective role of barrier against Trans epidermal water loss (TEWL). This review explores various classes of skin hydrating agents, including humectants, emollients, and occlusives, along with their mechanisms of action. Humectants, suc

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Tjandra, Oentarini, Linda J. Wijayadi, and Marcella E. Rumawas. "Green tea moisturizer improves skin hydration in elderly." Universa Medicina 37, no. 1 (2018): 3. http://dx.doi.org/10.18051/univmed.2018.v37.3-12.

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BACKGROUND<br />Dry skin is a major skin health problem in elderly. Green tea, which has an antioxidant effect, has recently been used as an active ingredient in moisturizing creams; yet the effect has not been well studied. This study compares the skin hydration effect of green tea and vitamin E moisturizer among elderly.<br /><br />METHODS<br />This quasi-experimental study involved 60 elderly living in Tresna Werda Budi Mulia 4 Social Institution, Jakarta. Using the Runve HL 611 skin analyzer, skin capacitance was measured prior to experiment and every following week

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You, Long, Mi-Yeon Kim, and Jae Youl Cho. "Protective Effect of Potentilla glabra in UVB-Induced Photoaging Process." Molecules 26, no. 17 (2021): 5408. http://dx.doi.org/10.3390/molecules26175408.

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Maintaining skin homeostasis is one of the most important factors for skin health. UVB-induced skin photoaging is a difficult problem that has negative impacts on skin homeostasis. So far, a number of compounds have been discovered that improve human skin barrier function and hydration, and are thought to be effective ways to protect skin homeostasis. Potentilla glabra var. mandshurica (Maxim.) Hand.-Mazz. Ethanol Extract (Pg-EE) is a compound that has noteworthy anti-inflammatory properties. However, its skin-protective effects are poorly understood. Therefore, we evaluated the capacity of Pg

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Rahmawati, Fitri, Linda Julianti Wijayadi, and Sari Mariyati Dewi N. "Overview of workers hand skin hydration levels on tofu maker at the tofu factory in Matraman district, East Jakarta." Science Midwifery 10, no. 4 (2022): 2977–84. http://dx.doi.org/10.35335/midwifery.v10i4.746.

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The parameters of human skin health can be assessed from the level of skin hydration. Skin hydration level is the water content in the stratum corneum which is strongly influenced by natural moisturizing factor (NMF) and intercellular lipids. These components can be disrupted when exposed to irritants, such as detergents, too acidic substances, and so on. This condition can cause a decrease in skin hydration levels and becomes inactive, thereby it increases the skin's sensitivity to exogenous factors and infections. Traditional tofu factory workers are workers who have a risk of experiencing a

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Zhang, Ke, Chenxu Zhao, Kaiyue Liu, et al. "Oral Administration of Deer Bone Collagen Peptide Can Enhance the Skin Hydration Ability and Antioxidant Ability of Aging Mice Induced by D-Gal, and Regulate the Synthesis and Degradation of Collagen." Nutrients 16, no. 11 (2024): 1548. http://dx.doi.org/10.3390/nu16111548.

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Skin problems caused by aging have attracted much attention, and marine collagen peptides have been proved to improve these problems, while mammalian collagen peptides are rarely reported. In this study, fermented deer bone collagen peptide (FCP) and non-fermented deer bone collagen peptide (NCP) were extracted from fermented and non-fermented deer bone, respectively, and their peptide sequences and differential proteins were analyzed using LC-MS/MS technology. After they were applied to aging mice induced with D-gal, the skin hydration ability, antioxidant ability, collagen synthesis, and deg

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Kumar, Pradeep* Kaur Amarjeet Chauhan Priya. "A Review Article on Formulation of Moisturizing Cream." International Journal of Pharmaceutical Sciences 3, no. 5 (2025): 666–71. https://doi.org/10.5281/zenodo.15337695.

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Moisturizing creams are essential dermatological products used to maintain skin hydration, improve barrier function, and manage various skin disorders. These formulations vary significantly in their ingredients, mechanisms of action, and intended use. This review discusses the types, functions, mechanisms, clinical applications, and recent advancements in moisturizing creams, with emphasis on scientific research and clinical evidence.

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Sukmawati Tansil Tan, Alexander Halim Santoso, Ernawati Ernawati, Yohanes Firmansyah, Joshua Kurniawan, and Jasmine Syabania Noviantri. "Community Service Activities – Education And Skin Hydration Screening For Productive Age Group." Perigel: Jurnal Penyuluhan Masyarakat Indonesia 2, no. 2 (2023): 06–14. http://dx.doi.org/10.56444/perigel.v2i2.727.

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Hydration of the epidermis refers to the maintenance of the skin's natural moisture balance. This is accomplished by providing and sustaining an adequate level of moisture in the skin layer. Hydration of the skin is essential for sustaining healthy and beautiful skin, as well as preventing skin issues like dryness, redness, irritation, and premature aging. The Skin Hydration Counseling and Screening activities seek to prevent dry skin issues by educating the public on the significance of maintaining skin hydration. Through this activity, participants learned about the risk factors for dry skin

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Rizzo, Julianne, Mildred Min, Sarah Adnan, et al. "Soy Protein Containing Isoflavones Improves Facial Signs of Photoaging and Skin Hydration in Postmenopausal Women: Results of a Prospective Randomized Double-Blind Controlled Trial." Nutrients 15, no. 19 (2023): 4113. http://dx.doi.org/10.3390/nu15194113.

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Preliminary findings from multiple studies indicate that dietary intake of soy-derived isoflavones exert beneficial effects on the skin including defense against oxidant damage, stimulation of collagen synthesis, and increased hydration. This study aims to investigate how oral supplementation of a soy protein isolate with added isoflavones (SPII) affects components of photoaging such as facial wrinkles and dyspigmentation, and skin biophysical measures such as skin hydration and sebum excretion in postmenopausal women. This 6-month prospective, randomized double-blind controlled study was cond

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Douladiris, Nikolaos, Efstratios Vakirlis, and Emilia Vassilopoulou. "Atopic Dermatitis and Water: Is There an Optimum Water Intake Level for Improving Atopic Skin?" Children 10, no. 2 (2023): 273. http://dx.doi.org/10.3390/children10020273.

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Water is a vital nutrient with innumerable functions for every living cell. The functions of human skin include protection against dehydration of the body. Atopic dermatitis (AD) is a chronic pruritic inflammatory skin disease that presents with dry skin, erythematous and eczematous lesions, and lichenification. This paper discusses the question of whether extra water intake in children with AD affects skin hydration and the skin barrier function. Among the methods used to treat dry skin, topical leave-on products are the first-line treatment, intended to improve hydration and the skin barrier

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Tomasino, Frederica, Maria Lídia Palma, Carla Monteiro, Liliana Tavares, Julia Bujan, and Luis Monteiro Rodrigues. "Dietary water seems to improve skin hydration without influencing hemodynamics." Journal Biomedical and Biopharmaceutical Research 10, no. 1 (2013): 43–54. http://dx.doi.org/10.19277/bbr.10.1.50.

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Liaqat, Sidrah, Kia Dashtipour, Kamran Arshad, and Naeem Ramzan. "Non Invasive Skin Hydration Level Detection Using Machine Learning." Electronics 9, no. 7 (2020): 1086. http://dx.doi.org/10.3390/electronics9071086.

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Dehydration and overhydration can help to improve medical implications on health. Therefore, it is vital to track the hydration level (HL) specifically in children, the elderly and patients with underlying medical conditions such as diabetes. Most of the current approaches to estimate the hydration level are not sufficient and require more in-depth research. Therefore, in this paper, we used the non-invasive wearable sensor for collecting the skin conductance data and employed different machine learning algorithms based on feature engineering to predict the hydration level of the human body in

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Stanko-Nieniewska, Maja. "The impact of microneedle mesotherapy treatment on anti-aging prevention and reduction of skin aging symptoms – subjective evaluation of the effectiveness of the treatment." Aesthetic Cosmetology and Medicine 13, no. 5 (2024): 177–88. http://dx.doi.org/10.52336/acm.2024.026.

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The ageing of human facial skin is an inevitable process. With age, wrinkles appear, the skin becomes thinner, there is a decrease in hydration, elasticity and firmness, and a general loss of vitality. This study aimed to evaluate the effectiveness of microneedle mesotherapy in preventing and reducing the signs of skin ageing in women who underwent a series of microneedle mesotherapy treatments. Microneedle mesotherapy treatments significantly improve skin tone and firmness, lift the oval of the face, increase skin hydration and reduce wrinkles. In recent years, microneedle mesotherapy has gai

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Camargo Junior, Flavio Bueno de, Lorena Rigo Gaspar, and Patrícia Maria Berardo Gonçalves Maia Campos. "Immediate and long-term effects of polysaccharides-based formulations on human skin." Brazilian Journal of Pharmaceutical Sciences 48, no. 3 (2012): 547–55. http://dx.doi.org/10.1590/s1984-82502012000300022.

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A new trend in cosmetic formulations is the use of biotechnological raw materials as the polysaccharides from Klebsiella pneumoniae, which are supposed to enhance cell renewal, improve skin hydration and micro-relief. Botanical extracts of Myrtus communis leaves contain different sugars, which may provide the same benefits. Thus, the objective of this study was to evaluate through objective and subjective analysis the immediate and long-term effects of cosmetic formulations containing polysaccharides biotechnologically-originated and / or the ones contained in Myrtus communis extracts. Three p

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Załęcki, Piotr, Karolina Rogowska, Paulina Wąs, Kamila Łuczak, Marta Wysocka, and Danuta Nowicka. "Impact of Lifestyle on Differences in Skin Hydration of Selected Body Areas in Young Women." Cosmetics 11, no. 1 (2024): 13. http://dx.doi.org/10.3390/cosmetics11010013.

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Measuring skin hydration is important for dermatology research, cosmetic practice, and daily skincare; it provides valuable insight into skin assessment and predicts treatment outcomes. This study investigated the level of skin hydration on various parts of the body in female university students, utilizing corneometry for measurement. Demographic, water intake, skincare, and exercise habit data were collected. The highest hydration levels were on the face (n = 40), followed by cleavage skin (n = 42), neck skin (n = 48), and leg skin (n = 42). Differences were observed between the chin and fore

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Keck, Cornelia M., Em-on Chaiprateep, Henriette Dietrich, and Soma Sengupta. "Influence of Mechanical Skin Treatments on Dermal Penetration Efficacy of Active Ingredients." Pharmaceutics 14, no. 9 (2022): 1788. http://dx.doi.org/10.3390/pharmaceutics14091788.

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The effective dermal penetration of active ingredients (AI) is a major task in the formulation of topical products. Besides the vehicle, the mechanical skin treatments are also considered to impact the penetration efficacy of AI. In particular, professional skin treatments, i.e., professional cosmetic skin treatments, are considered to be optimal for the dermal delivery of AI. However, a systematic study that proves these theories is not yet available and was therefore performed in this study while utilizing an ex vivo porcine ear model with subsequent digital image analysis. Hydrophilic and l

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Gruber, James V., Venera Stojkoska, and Jed Riemer. "Retinol Has a Skin Dehydrating Effect That Can Be Improved by a Mixture of Water-Soluble Polysaccharides." Cosmetics 7, no. 4 (2020): 80. http://dx.doi.org/10.3390/cosmetics7040080.

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It is common that retinoids used in skincare can cause skin dryness, irritation and redness which is a complaint for the use of these molecules in skincare formulations. Objective: to investigate the influence of a mixture of polysaccharides to improve retinol-based formulations in a 12-day inner volar forearm study. Methods: in total, 22 inner volar forearms were treated over a 12-day topical application of a Placebo formulation containing 0.5% retinol verses a formulation containing 0.5% retinol and 3.0% of a complex of polysaccharides. Application occurred 2X/day in the morning and evening.

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Permatasari, Nabila Jingga, and Sukmawati Tansil Tan. "Efektivitas Niacinamide Topikal terhadap Hidrasi Kulit pada Individu dengan Akne Vulgaris." Malahayati Nursing Journal 6, no. 12 (2024): 5143–50. http://dx.doi.org/10.33024/mnj.v6i12.15839.

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ABSTRACT Nowadays, many skincare products use niacinamide as their base ingredient. Niacinamide, also known as vitamin B3, has the potential to enhance ceramide synthesis and improve the skin barrier function. Due to those potentials, niacinamide can improve someone’s skin hydration level. To find out the efficacy of topical niacinamide on skin hydration levels on individuals with acne vulgaris. Through a quasi-experimental study design, this study was conducted for 21 days at 75 North Jakarta State High School with respondents of 59 people who are suffering from acne vulgaris. The method that

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Muhammad Ammar Khan. "A Comprehensive Analysis of Hydrolyzed Collagen Supplementation Effects on Skin Aging and Texture and Its Potential Benefits for Osteoarthritis." Indus Journal of Bioscience Research 3, no. 5 (2025): 911–16. https://doi.org/10.70749/ijbr.v3i5.1601.

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Background: Hydrolyzed collagen supplementation has gained popularity for its potential to improve skin health and combat signs of aging. This study investigates its effects on skin elasticity, hydration, and texture over a 12-week intervention period. Objective: To evaluate the efficacy of hydrolyzed collagen supplementation in reducing visible signs of skin aging and improving overall skin health and its potential benefits for osteoarthritis. Methods: A randomized, double-blind, placebo-controlled study was conducted with 55 participants aged 25–60 years from March 2024 to September 2024. Th

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Aich, Biswajit, Preeti Kumbhar, Snehal Muchhala, Arti Sanghavi, Sagar Katare, and Bhavesh Kotak. "Clinical evaluation of a topical ceramide lotion on skin hydration and skin barrier in healthy volunteers with dry skin." Cosmoderma 4 (December 30, 2024): 148. https://doi.org/10.25259/csdm_175_2024.

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Objectives: Ceramides are epidermal lipids important for normal skin barrier function. Reduced ceramide content is associated with dry skin and atopic dermatitis (AD) due to increased transepidermal water loss (TEWL) and worsening symptoms. Topical ceramide application restores barrier function and improves hydration by reducing TEWL. The objective of the present study was to evaluate the effect of a test product on skin hydration and TEWL on the volar forearms of adults, by comparing measurements at 12 and 24 h post-application. Materials and Methods: This single-center and non-randomized stu

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Baumann, Julia, Eva Bönzli, Franziska Wandrey, and Torsten Grothe. "Moldavian Dragonhead Extract: A Natural Collagen-Booster to Target Skin Aging." OBM Geriatrics 09, no. 02 (2025): 1–22. https://doi.org/10.21926/obm.geriatr.2502305.

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The complex process of skin aging results in noticeable changes, including decreased collagen content, reduced elasticity, and decreased hydration. Interventions to preserve or restore collagen, a key structural protein, may help counteract these signs. The concept of "beauty from within” through nutritional supplements is of growing interest, particularly the use of plant-based alternatives to animal-derived or synthetic collagen. This study investigated the anti-aging potential of an extract from Moldavian dragonhead (<em>Dracocephalum moldavica</em> L.), a natural plant-based co

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Baek, Yujin, Ngoc Ha Nguyen, Young In Lee, et al. "Hibiscus Collagen Alternative (VC-H1) as an Oral Skin Rejuvenating Agent: A 12-Week Pilot Study." International Journal of Molecular Sciences 26, no. 15 (2025): 7291. https://doi.org/10.3390/ijms26157291.

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Skin aging causes reduced hydration, elasticity, and increased wrinkles. Recent safety and compliance concerns over oral collagen supplements have increased interest in plant-based alternatives like Hibiscus sabdariffa with antioxidant and anti-aging properties. However, clinical evidence regarding its efficacy remains limited. We aimed to evaluate the effects of this plant-based collagen alternative (VC-H1, Hibiscus Enzyme Extract) supplement on skin hydration, transepidermal water loss (TEWL), desquamation, elasticity, and wrinkle reduction in photoaged individuals. A randomized, double-blin

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Prestat-Marquis, Elodie. "Non-invasive in vivo methods to measure lipidic formulae efficacy at the skin surface: advantages and limits." OCL 25, no. 5 (2018): D509. http://dx.doi.org/10.1051/ocl/2018051.

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Lipids are major ingredients in cosmetics and play an essential role in cosmetics ability to improve skin, hair, nail and mucuous membranes aspect, sensory qualities and function, either by interacting with skin components, enhancing active ingredient release or by spreading and forming a protective layer on its surface. Measuring lipids efficacy to the skin is possible through a wide range of non-invasive clinical and instrumental methods. Measurements of sebum, temperature, hydration, transepidermal water loss, skin surface topography, skin firmness, elasticity, color enable to assess the li

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Roh, Hyo Lyun, and Hyo Taek Lee. "Effects of paraffin wax and loess on skin hydration and texture." International Journal of Innovative Research and Scientific Studies 8, no. 3 (2025): 529–35. https://doi.org/10.53894/ijirss.v8i3.6557.

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This study aimed to evaluate the effects of a paraffin wax and loess mixture compared to paraffin wax alone on skin hydration and texture enhancement. A total of 20 adult male and female participants were involved. Two types of treatments—pure paraffin wax and a paraffin-loess mixture—were applied to the dorsal side of the participants’ hands. Skin hydration, oil-moisture balance, and texture (softness) were measured before and after treatment using a validated skin analysis device. Both treatments led to improvements in skin moisture and softness. However, the paraffin-loess mixture demonstra

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Chilicka, Karolina. "Estimation of selected skin parameters during a series of beauty treatments in women with acne: a pilot study." Medical Science Pulse 15, no. 1 (2021): 1–10. http://dx.doi.org/10.5604/01.3001.0014.8697.

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Background: Acne vulgaris occurs most often in young people and can significantly decrease the quality of life. Properly selected dermatological therapy and cosmetic procedures can effectively improve the skin condition of acne patients. Aim of the study: The aim of this study was to examine how various cosmetics treatments affect facial sebum levels, skin hydration, and desquamation in young women with acne vulgaris. Material and Methods: 101 women with acne aged 19–29 (M = 22.5 years, SD = 2.3 years) were included in the study. The following cosmetic treatments were used over a 12-week perio

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Wijayadi, Linda Julianti, and Kelvin Kelvin. "The Role of Essential Oils on Improving Elderly Skin Hydration." Science Midwifery 10, no. 4 (2022): 3104–11. http://dx.doi.org/10.35335/midwifery.v10i4.769.

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Skin hydration has an important role in various diseases of the elderly. Skin hydration is determined by two factors, namely the ability of the stratum corneum (SC) to retain water due to natural moisturizing factors and the barrier function of the intercellular lipid lamellar structure and tight junctions. Several parameters are usually used for skin hydration, such as surface water content (SWC) and trans-epidermal water loss (TEWL). With age, several changes in the skin affect hydration, including changes in the cellular and intercellular lipid matrix, skin pH, SC protease enzymes, decrease

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Wanitphakdeedecha, Rungsima, Sasima Eimpunth, and Woraphong Manuskiatti. "The Effects of Mucopolysaccharide Polysulphate on Hydration and Elasticity of Human Skin." Dermatology Research and Practice 2011 (2011): 1–5. http://dx.doi.org/10.1155/2011/807906.

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Background. Mucopolysaccharide polysulphate (MPS) has been used in medicine as an anti-inflammatory and antithrombotic agent for over 50 years. Its chemical structure permits considerable hydrogen bonding with adjacent water molecules, which effectively leads to hydration of the surrounding tissue. In addition, it stimulates endogenous hyaluronate synthesis, resulting in an increase in water-binding capacity and viscoelasticity of the skin.Objective. To study the efficacy of 0.1% MPS on hydration and elasticity of human skin.Methods. The first part of this study was a randomized double blind p

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Vedamurthy, Maya, Vaishnavi Duvvuru, and Vijaya Lakshmi Chelikani. "Skin boosters – The upcoming boom in cosmetic dermatology for healthy skin." Cosmoderma 3 (May 29, 2023): 82. http://dx.doi.org/10.25259/csdm_93_2023.

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Skin-booster injections are popular esthetic treatments that are highly sought after because they are minimally invasive. They are used as one of the skin rejuvenation therapies to restore healthy hydrating skin of not only the face but also the neck, hands, and other regions of the body. Skin boosting is a revolutionary method of delivering either hyaluronic acid (HA) infused with other vitamins, amino acids, and antioxidants or HA per se to stimulate the body’s natural response that is to make more collagen and elastin. Extrinsic and intrinsic factors affect the quality and vitality of our s

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Gayatri, Chude* Asawali Pawar Swati Deshmukh. "Formulation And Evaluation of Face Serum by Using Rose and Beatroot Extract." International Journal of Pharmaceutical Sciences 3, no. 5 (2025): 1744–53. https://doi.org/10.5281/zenodo.15382816.

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This research paper focuses on the formulation and evaluation of a face serum using rose and beetroot extracts, leveraging their antioxidant, anti-inflammatory and skin-protective properties. The serum was formulated using a combination of rose and beetroot extracts, along with other natural ingredients and its physical and chemical stability, texture, and efficacy were evaluated. This research paper presents the formulation and evaluation of a face serum utilizing rose and beetroot extracts, renowned for their antioxidant, anti-inflammatory and skin-protective properties. The primary objectiv

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Abruzzo, Angela, Carola Parolin, Elisa Corazza, et al. "Influence of Lactobacillus Biosurfactants on Skin Permeation of Hydrocortisone." Pharmaceutics 13, no. 6 (2021): 820. http://dx.doi.org/10.3390/pharmaceutics13060820.

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One of the most widely used strategies to improve drug diffusion through the skin is the use of permeation enhancers. The aim of this work was to investigate the effect of two biosurfactants (BS), produced by Lactobacillus crispatus BC1 and Lactobacillus gasseri BC9, on the skin permeation profile of hydrocortisone (HC, model drug). HC aqueous solubility and in vitro diffusion studies through porcine skin were performed in the presence of BC1-BS and BC9-BS at concentrations below and above critical micellar concentrations (CMC). Moreover, skin hydration tests and differential scanning calorime

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Aadesh Sunil Gadhave and Bhavana Dnyandeo Tambe. "Moisturizing Hibiscus body lotion." International Journal of Science and Research Archive 14, no. 3 (2025): 472–76. https://doi.org/10.30574/ijsra.2025.14.3.0581.

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The increasing demand for natural and herbal skincare products has led to significant advancements in the cosmetic industry. This study focuses on the development of an herbal body lotion infused with Hibiscus flower extract (Hibiscus rosa-sinensis), renowned for its skin-enhancing properties. Hibiscus contains bioactive compounds such as anthocyanins, flavonoids, polyphones, vitamin C, and mucilage, which contribute to its antioxidant, anti-inflammatory, and hydrating effects. The study outlines the extraction process of hibiscus flower bioactives, formulation of the lotion using natural emul

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Kovács, Anita, Dóra Péter-Héderi, Katalin Perei, et al. "Effects of Formulation Excipients on Skin Barrier Function in Creams Used in Pediatric Care." Pharmaceutics 12, no. 8 (2020): 729. http://dx.doi.org/10.3390/pharmaceutics12080729.

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Semisolid dosage forms are recommended for the dermal care of babies and children. If we look at the ingredients of these preparations, there are still many cases in which there are substances (occlusive agents, preservatives) that no longer meet certain requirements of the modern age, so it is timely to replace them with other substances. The aim of this work was to formulate a science-based formulation with new components that keep or improve its moisturizing properties, rheological parameters, and microbiological stability. Occlusive oils, like white petrolatum and liquid paraffin and the p

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Hahm, Kyung Man, See-Hyoung Park, Sae Woong Oh, et al. "Aspergillus oryzae-Fermented Wheat Peptone Enhances the Potential of Proliferation and Hydration of Human Keratinocytes through Activation of p44/42 MAPK." Molecules 26, no. 19 (2021): 6074. http://dx.doi.org/10.3390/molecules26196074.

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Identifying materials contributing to skin hydration, essential for normal skin homeostasis, has recently gained increased research interest. In this study, we investigated the potential benefits and mechanisms of action of Aspergillus oryzae-fermented wheat peptone (AFWP) on the proliferation and hydration of human skin keratinocytes, through in vitro experiments using HaCaT cell lines. The findings revealed that compared to unfermented wheat peptone, AFWP exhibited an improved amino acid composition, significantly (p < 0.05) higher DPPH scavenging capability and cell proliferation activit

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Aich, Biswajit, Preeti Kumbhar, Arti Sanghavi, Snehal Muchhala, Sagar Katare, and Bhavesh Kotak. "Evaluation of skin hydration and anti-itch properties after application of a novel urea-based moisturizing cream." Cosmoderma 5 (April 11, 2025): 40. https://doi.org/10.25259/csdm_209_2024.

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Objectives Moisturizers are crucial in improving skin hydration and reducing transepidermal water loss (TEWL), especially in individuals with dry skin. This study aims to evaluate Venusia Ureka Cream’s efficacy in enhancing skin hydration, reducing TEWL, and providing itch relief in individuals with dry, itchy skin. Materials and Methods This single-center, observational study enrolled participants with dry skin. Participants applied Venusia Ureka Cream at four test sites on their forearms, with four control sites left untreated. Skin hydration and TEWL were measured using the MoistureMeter st

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Leo, Teik Kee, Eugenie Sin Sing Tan, Farahnaz Amini, Navedur Rehman, Edmond Siah Chye Ng, and Chung Keat Tan. "Effect of Rice (Oryza sativa L.) Ceramides Supplementation on Improving Skin Barrier Functions and Depigmentation: An Open-Label Prospective Study." Nutrients 14, no. 13 (2022): 2737. http://dx.doi.org/10.3390/nu14132737.

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Ceramides plays a crucial role in maintaining skin barrier function. Although foregoing evidence supported beneficial effects of topical ceramides for restoration of the skin barrier, studies on oral ceramides are extremely scarce, with most published data collected from in vivo and in vitro models. Thus, this study aimed to evaluate the efficacy of rice ceramides (RC) supplementation to improve skin barrier function and as a depigmenting agent through comprehensive clinical assessments. This study investigated the beneficial effects of orally administered RC supplementation in 50 voluntary pa

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Kim, Sungwoo, Yeonjae Kim, Juyeon Jung, et al. "Clinical Efficacy of Endocannabinoid-Mimetic Fatty Acid Amide as a Skin-Soothing Ingredient." Cosmetics 11, no. 6 (2024): 225. https://doi.org/10.3390/cosmetics11060225.

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Despite the potential benefits of cannabidiol as a skin-soothing ingredient, its regulatory status hampers its general use in cosmetic products in many countries. To develop an alternative to cannabidiol, fatty acid amide molecules mimicking the chemical structure of endocannabinoids were manufactured using a lipase-catalyzed process. A mixture of fatty acid amides from sunflower oil and 1-amino propan-3-ol was synthesized using an immobilized lipase reaction, and the activation of cannabinoid receptor 1 (CB1R) was measured using a cAMP assay. The anti-inflammatory activity of the endocannabim

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Lee, Sang Gyu, Ngoc Ha Nguyen, Young In Lee, et al. "The Role of Cacao Powder in Enhancing Skin Moisture and Reducing Wrinkles: A 12-Week Clinical Trial and In Vitro Study." Current Issues in Molecular Biology 46, no. 11 (2024): 12574–87. http://dx.doi.org/10.3390/cimb46110746.

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Skin aging is driven by a combination of internal and external mechanisms, with ultraviolet (UV) radiation being a prominent external factor contributing to photoaging. Photoaging manifests through several signs, including decreased skin hydration, diminished elasticity, coarse wrinkles, and dyspigmentation. Cacao beans, known for their flavonoids and polyphenols, offer potential anti-aging benefits. To explore this, we conducted a study using both in vitro experiments and clinical trials. Our results demonstrated that cacao powder significantly improved skin hydration and moisture retention i

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Nogerov, A. R. "Experience of using a complex preparation of hybrid polylactic acid in the correction of involutional changes in the skin." Medical alphabet, no. 8 (June 4, 2025): 106–10. https://doi.org/10.33667/2078-5631-2025-8-106-110.

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Material and methods. We observed 20 female patients aged 30 to 40 years (median 36.7±1.9 years) who came to the appointment with complaints of involutional changes in the facial skin (xerosis, decreased turgor, wrinkles). All patients underwent injection therapy procedures: Lenisna – facial contouring (temporal area, cheek area, chin), JuveLook – for the periorbital area. Efficiency was assessed using the SASSQ scale, qualitative characteristics of the skin (hydration, elasticity, severity of wrinkles).Results of the study. The dynamics of the SASSQ scale was 45.6%, skin hydration increased a

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Płatkowska, Anna, Szymon Korzekwa, Bartłomiej Łukasik, and Nicola Zerbinati. "Combined Bipolar Radiofrequency and Non-Crosslinked Hyaluronic Acid Mesotherapy Protocol to Improve Skin Appearance and Epidermal Barrier Function: A Pilot Study." Pharmaceuticals 16, no. 8 (2023): 1145. http://dx.doi.org/10.3390/ph16081145.

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Background: Age-associated changes in epidermal hydration, pigmentation, thickness and cell renewal influence skin appearance and can lead to laxity, dryness and poor skin tone. The aim of this pilot study was to assess the synergistic effects of a new bipolar radiofrequency plus non-crosslinked hyaluronic acid (HA) mesotherapy protocol compared with radiofrequency alone on skin appearance and markers of epidermal function. Methods: This prospective, single-center, split-face pilot study recruited women aged 25–65 years with dryness and laxity of the facial skin defined by a trans-epidermal wa

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Kim, Young Jae, Ik Jun Moon, Hae Woong Lee, et al. "The Efficacy and Safety of Dual-Frequency Ultrasound for Improving Skin Hydration and Erythema in Patients with Rosacea and Acne." Journal of Clinical Medicine 10, no. 4 (2021): 834. http://dx.doi.org/10.3390/jcm10040834.

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Inflammatory skin diseases, such as rosacea and acne, are major causes of facial erythema and accompanying skin barrier dysfunction. Several methods to restore the impaired skin barrier and improve facial erythema, such as medication, radiofrequency, laser, and ultrasound therapy were attempted. This study evaluated the efficacy and safety of dual-frequency ultrasound with impulse mode, for improving skin hydration and erythema in Asian subjects with rosacea and acne. Twenty-six subjects with facial erythema received an ultrasound treatment once per week, for 4 weeks, over both cheeks. The ery

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McLoughlin, Isabella J., Abigail L. Voss, John D. F. Hale, and Rohit Jain. "Cosmetic Efficacy of the Topical Probiotic Micrococcus luteus Q24 in Healthy Human Adults." Cosmetics 11, no. 4 (2024): 122. http://dx.doi.org/10.3390/cosmetics11040122.

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Probiotics in cosmetics represent a new and burgeoning area of research, attracting attention from cosmetic manufacturers and customers looking for natural or additional alternatives in their skincare regimens. Probiotics not only promote beneficial microbiomes to improve skin health but can also modulate the visual, topographical, and mechanical attributes to improve skin quality. This study was conducted in healthy adults to determine the effect of direct skin application of a topical serum formulation containing the live probiotic Micrococcus luteus Q24 on several key cosmetic skin quality

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Neha, Shaikh* Dr. Swati Deshmukh Ashish Umale. "Development and Evaluation of a Chamomile Enriched Antiaging Face serum For Skin Regeneration." International Journal of Pharmaceutical Sciences 3, no. 5 (2025): 2135–48. https://doi.org/10.5281/zenodo.15397735.

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The formulation and development of a chamomile-enriched anti-aging face serum aims to harness the herb’s antioxidant, anti-inflammatory and skin-soothing properties for enhanced skin regeneration. By combining chamomile extract with other natural ingredients, this serum targets fine lines, wrinkles and skin elasticity.  the serum demonstrates efficacy in promoting collagen synthesis, reducing oxidative stress, and improving skin hydration. With excellent stability, safety, and tolerability, this chamomile-enriched face serum offers a promising natural solution for anti-aging skincar

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Jackson, Luke, Jonathan Noah, Miguel Seth, and Collin Jared. "Skin Care Using Heparinoid Creams for Long-Term Treatment with Oxybutynin Transdermal Patches without Skin Irritation in Elderly OAB Patients." Dermatology and Dermatitis 2, no. 1 (2018): 01–03. http://dx.doi.org/10.31579/2578-8949/020.

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Background: Overactive bladder is an age-related urologic disease. An oxybutynin transdermal patch is used to treat overactive bladder; however, long-term use is not advised because of potential adverse reactions at the site of application. The present study aimed to investigate the advantages of administering a combination of heparinoid cream and oxybutynin transdermal patch treatment for overactive bladder in elderly patients. Methods: Eight patients (>65 years of age) with overactive bladder were included. The heparinoid cream was applied topically for 1 week, and skin hydration and tran

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Rusic, Doris, Magdalena Ivic, Ana Slugan, et al. "Pilot Study on the Effects of a Cosmetic Serum Containing Niacinamide, Postbiotics and Peptides on Facial Skin in Healthy Participants: A Randomized Controlled Trial." Life 14, no. 12 (2024): 1677. https://doi.org/10.3390/life14121677.

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The literature describes niacinamide, but also postbiotics and peptides, as ingredients that improve skin barrier function, but also affect melanin and sebum levels in individuals. However, the combined effects of these ingredients in a single cosmetic serum have not been sufficiently investigated. Therefore, the aim of this randomized controlled study, conducted at the University of Split School of Medicine (Croatia), was to evaluate the effects of cosmetic products containing these active ingredients. This study was registered with ClinicalTrials.gov (NCT06189105) and has been completed. Pri

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Kazimierska, Kinga, Anna Erkiert-Polguj, and Urszula Kalinowska-Lis. "The Efficacy of a Cosmetic Preparation Containing Sheep Colostrum on Mature Skin: A Randomized Placebo-Controlled Double-Blind Study." Applied Sciences 14, no. 7 (2024): 2862. http://dx.doi.org/10.3390/app14072862.

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Colostrum, the first milk produced by mammals, is rich in various bioactive components that provide numerous health benefits to newborns, such as growth factors, hormones, immunoglobulins, cytokines, and enzymes. Topical application of bovine or equine colostrum has been found to improve regeneration, accelerate cutaneous wound healing, and have moisturizing, protective, and anti-aging properties. The aim of this study was to examine the effect of a cosmetic preparation containing sheep colostrum on skin with signs of aging in mature women. Fifty-two women, aged 40–70, were randomized into two

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Erkiert-Polguj, Anna, Kinga Kazimierska, and Urszula Kalinowska-Lis. "Assessment of the Impact of a Cosmetic Product with Sheep Colostrum on Acne Skin." Applied Sciences 14, no. 5 (2024): 2199. http://dx.doi.org/10.3390/app14052199.

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Colostrum, the first secretion of mammalian breasts after giving birth, contains a wealth of components believed to have a beneficial effect on human skin, including lactoferrin, immunoglobulin (Ig)A, beta-carotene, fat-soluble vitamins, and zinc. The present study examines the effect of a cosmetic preparation containing 15% lyophilisate of sheep colostrum on acne skin. A group of 27 volunteers with mild or moderate acne applied the cream twice a day for eight weeks. Before and after using the cream, the level of skin hydration, sebum level, and TEWL were measured using a standardized Courage–

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Proksch, Ehrhardt, Denise Zdzieblik, and Steffen Oesser. "The Oral Intake of Specific Bovine-Derived Bioactive Collagen Peptides Has a Stimulatory Effect on Dermal Matrix Synthesis and Improves Various Clinical Skin Parameters." Cosmetics 12, no. 2 (2025): 79. https://doi.org/10.3390/cosmetics12020079.

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Collagen products are widely marketed for skin improvement. This study evaluated the efficacy of VERISOL B in relation to key skin aging parameters. In a double-blind, placebo-controlled trial, 66 women (aged 35–55) were randomized to receive either 2.5 g of bovine-derived bioactive collagen peptides (SCPs) (n = 33) or a placebo (n = 33) daily for 8 weeks. Their eye wrinkle volume, skin elasticity, and hydration were objectively measured at baseline (X0), 4 weeks (X4), and 8 weeks (X8). Additionally, the SCPs’ impact on type I collagen, elastin, and proteoglycan biosynthesis was assessed in hu

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Fluhr, Joachim W., Valérie Muguet, and Stéphanie Christen‐Zaech. "Restoring Skin Hydration and Barrier Function: Mechanistic Insights Into Basic Emollients for Xerosis Cutis." International Journal of Dermatology 64, S1 (2025): 5–12. https://doi.org/10.1111/ijd.17790.

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ABSTRACTHealthy skin is structured to maintain water balance by maximizing water retention and minimizing evaporative loss. The water‐holding and barrier functions of the skin can be impaired by several factors that lead to xerosis cutis (dry skin); however, they can also be restored by basic emollients that act through the physicochemical properties of their constituents. This article aims to give a narrative review of the physiology of normal skin hydration, the key pathophysiological mechanisms implicated in dry skin, and the functional effects of basic emollients for managing xerosis cutis

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Anggraeni, Sylvia, Menul Ayu Umborowati, Damayanti Damayanti, Anang Endaryanto, and Cita Rosita Sigit Prakoeswa. "Role of Centella asiatica and ceramide in skin barrier improvement: a double blind clinical trial of Indonesian batik workers." Journal of Basic and Clinical Physiology and Pharmacology 32, no. 4 (2021): 589–93. http://dx.doi.org/10.1515/jbcpp-2020-0510.

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Abstract Objectives Batik dyes contain irritant chemicals that increase the risk of skin barrier disruption. This study aims to determine the effect of Centella asiatica and ceramide in transepidermal water loss (TEWL), hydration of the stratum corneum and skin acidity (pH). Methods This was a double blind clinical trial of 30 Indonesian batik workers who suffered from skin dryness, but had no clinical manifestation of contact dermatitis. Subjects were given cream containing C. asiatica or ceramide that formulated and randomly labeled by manufacturer (PT Paragon Technology and Innovation). Bot

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Nobile, Vincenzo, Cother Hajat, Enza Cestone, Federica Cascella, and Giacomo Santus. "Skin Antiaging and Skin Health Benefits of Probiotic Intake Combined with Topical Ectoin and Sodium Hyaluronate: A Randomized, Double-Blind, Placebo-Controlled Trial." Cosmetics 12, no. 2 (2025): 34. https://doi.org/10.3390/cosmetics12020034.

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Well-aging strategies include the use of both oral and topic products to nourish the skin from the inside out. A clinical–instrumental study was conducted on 96 Caucasian subjects with mild-to-moderate facial aging to demonstrate the efficacy of probiotic (Lactobacillus plantarum PBS067, Lactobacillus reuteri PBS072, and Lactobacillus rhamnosus LRH020) intake combined with topical ectoin and sodium hyaluronate. The skin sebum content, hydration and moisturization, profilometry (wrinkle depth and skin smoothness), TEWL, elasticity (R0 and R2 parameters), radiance, and pores (size and impurities

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Woo, Chin Yee, Mark JA Koh, Winnie KY Fung, et al. "Effects of Cast Immobilisation on Skin Barrier Function." Annals of the Academy of Medicine, Singapore 49, no. 6 (2020): 354–59. http://dx.doi.org/10.47102/annals-acadmedsg.2019170.

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Introduction: Cast immobilisation remains the mainstay of treatment for various fractures in paediatric patients, yet patients commonly complain of skin irritation and discomfort. This study aimed to perform a qualitative and quantitative evaluation of the effects of cast immobilisation on the skin of children and adolescents. Materials and Methods: Patients aged 6–17 years of age with a fracture treated in a fiberglass short-arm or short-leg cast were recruited. Transepidermal water loss (TEWL), stratum corneum (SC) hydration, hair density and presence of any skin signs were assessed before a

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