Bibliografias temáticas / In vivo studies

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Literatura científica selecionada sobre o tema "In vivo studies"

Autor: Grafiati

Publicado: 4 de junho de 2021

Última modificação: 11 de março de 2023

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Artigos de revistas sobre o assunto "In vivo studies"

Naveed, Safila, Najma Sultana e Muhammad Saeed Arayne. "In vivo and in vitro interaction studies of ibuprofen with enalapril". Journal of Coastal Life Medicine 4, n.º 4 (abril de 2016): 327–30. http://dx.doi.org/10.12980/jclm.4.2016j5-198.

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Sharma, Rakesh Kumar, e Anil Kumar Midda. "Preparation of Sustained Release Microspheres of Aceclofenac: Characterization & in-vivo studies". International Journal of Research and Development in Pharmacy & Life Sciences 6, n.º 7 (dezembro de 2017): 2862–66. http://dx.doi.org/10.21276/ijrdpl.2278-0238.2017.6(7).2862-2866.

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Herbold, Bernd A., Susanne Y. Brendler-Schwaab e Hans Jürgen Ahr. "Ciprofloxacin: in vivo genotoxicity studies". Mutation Research/Genetic Toxicology and Environmental Mutagenesis 498, n.º 1-2 (novembro de 2001): 193–205. http://dx.doi.org/10.1016/s1383-5718(01)00275-3.

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Su, Muh-Hwan, V. Srinivasan, Abdel-Halim Ghanem e William I. Higuchi. "Quantitative in Vivo Iontophoretic Studies". Journal of Pharmaceutical Sciences 83, n.º 1 (janeiro de 1994): 12–17. http://dx.doi.org/10.1002/jps.2600830105.

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Pomare, E. W., L. C. Hillman, S. Peters e A. Fisher. "In vivo studies with fibre components". Scandinavian Journal of Gastroenterology 22, sup129 (janeiro de 1987): 181–84. http://dx.doi.org/10.3109/00365528709095881.

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Booij, L. H. D. J., J. van Egmond, J. J. Driessen e H. D. de Boer. "In vivo animal studies with sugammadex". Anaesthesia 64 (março de 2009): 38–44. http://dx.doi.org/10.1111/j.1365-2044.2008.05869.x.

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Fahmy, Maha A., e Kawthar A. E. Diab. "In vivo Genotoxicity Studies of Cefotaxime". CYTOLOGIA 74, n.º 4 (2009): 417–25. http://dx.doi.org/10.1508/cytologia.74.417.

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Kaufman, Herbert E. "IN VIVO STUDIES WITH ANTIVIRAL AGENTS*". Annals of the New York Academy of Sciences 130, n.º 1 (16 de dezembro de 2006): 168–80. http://dx.doi.org/10.1111/j.1749-6632.1965.tb12550.x.

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DUFFY, S., P. C. REID e F. SHARP. "In-vivo studies of uterine electrosurgery". BJOG: An International Journal of Obstetrics and Gynaecology 99, n.º 7 (julho de 1992): 579–82. http://dx.doi.org/10.1111/j.1471-0528.1992.tb13824.x.

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Nikitin, Alexander, Yi Wang e Emmanuel Giannelis. "In vivo toxicity studies of nanoparticles". Toxicology Letters 180 (outubro de 2008): S222. http://dx.doi.org/10.1016/j.toxlet.2008.06.094.

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Teses / dissertações sobre o assunto "In vivo studies"

Al-Duaij, Ahmed Yousuf Mohamed. "Studies of cartilage degradation in vivo". Thesis, Queen Mary, University of London, 1985. http://qmro.qmul.ac.uk/xmlui/handle/123456789/1366.

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A new method has been established to study cartilage breakdown in vivo. Cartilage was implanted into air pouches on the backs of mice or rats and loss of proteoglycan measured biochemically. Using the air pouch it was possible to produce various inflammatory environments either immune or non immune and examine the effects of these upon proteoglycan loss. It was found that the various type of inflammation failed to accelerate proteoglycan loss from implanted cartilage. Subsequently a variety of drugs used in the treatment of the arthropathies were examined for their effect on both inflammation and cartilage breakdown. Using xiphisternum a difference could be shown between non-steroidal anti-inflammatory drugs (NSAID) and d-penicillamine in that, NSAID failed to protect the cartilage whereas d-penicillamine prevented proteoglycan loss. This type of cartilage was not examined further, as it was not characteristic of articular cartilage - being surrounded by perichondrium. Later articular cartilage was implanted once again into different inflammatory situations and drug effects evaluated. It was found using this cartilage that all the drug 0 used protected from loss of proteoglycan and whereas some inhibited inflammation (indoniethacin and dexamethasohe), 2a levamisole had no effect in contrast, d-penicillamine potentiated the inflammatory response. Finally the mode of action of the drugs in this method is discussed.

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De, Varennes Benoit. "Ex-vivo canine heart preservation : metabolic studies". Thesis, McGill University, 1992. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=56680.

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The recently developed method of nuclear magnetic resonance spectroscopy allows for continuous monitoring of high energy phosphate compound (ATP and Phosphocreatine) and intracellular pH of tissues or whole organs. In other to better understand why ex-vivo hearts can be preserved for longer periods when perfused with oxygenated crystalloid solutions under hypothermic conditions, two groups of canine hearts were studied with nuclear magnetic resonance spectroscopy.
Group 1 = Canine hearts preserved for 4 hours by immersion into a 4$ sp circ$C saline solution.
Group 2 = Canine hearts preserved for 24 hours by continuous coronary perfusion with a modified oxygenated Krebs solution at 4$ sp circ$C.
The longer preservation of ATP and phosphocreatine, as well as the slower decrease of intracellular pH in Group II hearts are hypothesized to be the reasons why perfused hearts can be preserved for longer periods of time.

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Haggie, P. M. "Spectroscopic studies of labelled proteins in vivo". Thesis, University of Cambridge, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.599831.

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Although metabolic enzymes and metabolic pathways have been well characterised in vitro, understanding of the control of metabolic processes in vivo is relatively poor. The extrapolation of studies performed on purified proteins into the intact cell is questionable. Consequently, there is a need to study enzymes in vivo, however, there are a limited number of techniques available to study specific proteins in a minimally invasive manner. Reported in this thesis are studies in which techniques are developed to permit specific proteins to be distinguished using nuclear magnetic resonance (NMR) and fluorescence visibility. A method to selectively label proteins by the biosynthetic incorporation of amino acid analogs has been developed in Saccharomyces cerevisiae. This method is non-invasive, and the probes introduced into specific proteins are very small and relatively non-perturbing. Using an inducible expression system, pyruvate kinase 1 and citrate synthase 1 were synthesised in vivo and 5-fluorotryptophan in the growth medium was selectively incorporated into the proteins. This labelling permitted the visualisation of these proteins using non-invasive NMR of whole cells. A complementary optical technique was also developed. This method incorporated a fluorescent amino acid analog (5-hydroxytryptophan) into proteins to allow the study of the proteins using more sensitive fluorescence techniques in whole cells. 5-Hydroxytryptophan was successfully incorporated into phosphoglycerate kinase which permitted visualisation of the protein in whole cells using laser scanning confocal microscopy. For both pyruvate kinase 1 and citrate synthase 1, there was evidence of enzyme immobilisation in whole cells. These investigations present direct evidence for the association of enzymes in vivo. The implications of these results in terms of the organisation of metabolism are discussed. The fluorescence studies have important implications both in terms of studying proteins in vivo with microscopy and fluorimetry and in the development of techniques to fluorescently label proteins.

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Frost, Gwenda. "In vivo NMR studies of Debaryomyces hansenii". Thesis, University of Liverpool, 1991. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.316609.

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Preece, N. E. "Studies on chemical-induced autoxidation in vivo". Thesis, University of Surrey, 1986. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.376361.

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Marczinke, Beate Inge. "In vivo studies of viral ribosomal frameshifting". Thesis, University of Cambridge, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.624918.

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Karunakaran, Chandrapriya. "Role of Cavitation during Bulk ultrasound Ablation: Ex vivo and In vivo Studies". University of Cincinnati / OhioLINK, 2012. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1343051845.

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Carroll, N. J. H. "Studies on adherent and luminal gastric mucus in vivo". Thesis, University of Newcastle Upon Tyne, 1987. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.378844.

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Pearce, Neil William. "Gallbladder contractility : in vitro and in vivo studies". Thesis, University of Southampton, 2004. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.416098.

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Klenerman, Paul. "Immune responses against persistent viruses studies in vivo". Thesis, University of Oxford, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.272756.

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Livros sobre o assunto "In vivo studies"

Yasumura, Seiichi, Joan E. Harrison, Kenneth G. McNeill, Avril D. Woodhead e F. Avraham Dilmanian, eds. In Vivo Body Composition Studies. Boston, MA: Springer US, 1990. http://dx.doi.org/10.1007/978-1-4613-1473-8.

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J, Ellis K., Morgan W. D, Yasumura S, Associated Universities Inc, Brookhaven National Laboratory, Institute of Physical Sciences in Medicine (Great Britain) e United States. Dept. of Energy., eds. In vivo body composition studies. London: Institute of Physical Sciences in Medicine, 1987.

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International Symposium on In Vivo Body Composition Studies (1989 University of Toronto). In vivo body composition studies: Recent advances. New York: Plenum Press, 1990.

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Coyle, John E. In vivo digestibility studies of ruminant feed ingredients. Dublin: University College Dublin, 1996.

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Silvio, Lefèvre, ed. Marketing direto ao vivo, no Brasil. São Paulo: Makron Books do Brasil Editora, 1994.

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Wroblewski, Joanna. Studies on chondrocyte differentiation in vivo and in vitro. Stockholm: Kongl Carolinska Medico Chirurgiska Institutet, 1987.

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Clarke, Hilary. In vivo and in vitro studies on cyclosporine-induced nephrotoxicity. Dublin: University College Dublin, 1997.

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Payne, David. Biosafety in vivo and in vitro studies of human malaria. [Geneva]: World Health Organization, 1990.

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Exposure systems and dosimetry of large-scale in vivo studies. Konstanz: Hartung-Gorre, 2007.

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Armstrong, Rosemary. Studies relating to the "in vivo" measurement of cadmium and mercury. Birmingham: University of Birmingham, 1990.

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Capítulos de livros sobre o assunto "In vivo studies"

Kaur, Amandeep. "Ex Vivo Studies". In Springer Theses, 149–69. Cham: Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-73405-7_7.

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Chang, Lee-Hong, e Thomas L. James. "NMR Methods in Studies of Brain Ischemia". In In Vivo Spectroscopy, 135–58. Boston, MA: Springer US, 1992. http://dx.doi.org/10.1007/978-1-4757-9477-9_3.

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London, Robert E. "In Vivo 2H NMR Studies of Cellular Metabolism". In In Vivo Spectroscopy, 277–306. Boston, MA: Springer US, 1992. http://dx.doi.org/10.1007/978-1-4757-9477-9_6.

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Harrison, J. E., K. G. McNeill, S. S. Krishnan, T. A. Bayley, F. Budden, R. Josse, T. M. Murray et al. "Clinical Studies on Osteoporosis". In In Vivo Body Composition Studies, 83–88. Boston, MA: Springer US, 1990. http://dx.doi.org/10.1007/978-1-4613-1473-8_12.

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Schousboe, Arne. "Studies of Brain Metabolism: A Historical Perspective". In Neural Metabolism In Vivo, 909–20. Boston, MA: Springer US, 2011. http://dx.doi.org/10.1007/978-1-4614-1788-0_31.

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Missirlis, Y. F., e W. Lemm. "In vitro, in vivo or ex vivo studies". In Modern Aspects of Protein Adsorption on Biomaterials, 163–68. Dordrecht: Springer Netherlands, 1991. http://dx.doi.org/10.1007/978-94-011-3752-2_16.

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Berliner, Lawrence J., e Hirotada Fujii. "Some Applications of ESR to in Vivo Animal Studies and EPR Imaging". In In Vivo Spectroscopy, 307–19. Boston, MA: Springer US, 1992. http://dx.doi.org/10.1007/978-1-4757-9477-9_7.

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Allen, Peter S. "In Vivo NMR Spectroscopy". In In Vivo Body Composition Studies, 419–26. Boston, MA: Springer US, 1990. http://dx.doi.org/10.1007/978-1-4613-1473-8_59.

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Thangaraj, Parimelazhagan. "In Vivo Wound Healing Studies". In Progress in Drug Research, 151–57. Cham: Springer International Publishing, 2015. http://dx.doi.org/10.1007/978-3-319-26811-8_25.

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Zhou, Yi, He Li e Zhongju Xiao. "In Vivo Patch-Clamp Studies". In Patch Clamp Electrophysiology, 259–71. New York, NY: Springer US, 2020. http://dx.doi.org/10.1007/978-1-0716-0818-0_13.

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Trabalhos de conferências sobre o assunto "In vivo studies"

Ivorra, Antoni, e Boris Rubinsky. "Impedance Analyzer for in vivo Electroporation Studies". In Conference Proceedings. Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE, 2006. http://dx.doi.org/10.1109/iembs.2006.259410.

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Fares, Y., J. D. Goeschl, C. E. Magnuson, C. J. McKinney, R. L. Musser e B. R. Strain. "Positron emitters for in vivo plant studies". In The fourteenth international conference on the application of accelerators in research and industry. AIP, 1997. http://dx.doi.org/10.1063/1.52714.

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Proshina, Yulia M., e Nina A. Razumikhina. "In-vivo studies of human skin optical reflectance". In Saratov Fall Meeting '99, editado por Valery V. Tuchin, Dmitry A. Zimnyakov e Alexander B. Pravdin. SPIE, 2000. http://dx.doi.org/10.1117/12.381504.

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König, Karsten, Rainer Bückle, Martin Weinigel, Johannes Köhler, Peter Elsner e Martin Kaatz. "In vivo multiphoton tomography in skin aging studies". In SPIE BiOS: Biomedical Optics, editado por Nikiforos Kollias, Bernard Choi, Haishan Zeng, Reza S. Malek, Brian J. Wong, Justus F. R. Ilgner, Kenton W. Gregory et al. SPIE, 2009. http://dx.doi.org/10.1117/12.813398.

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Ling, Jian, Setsuo Takatani, George P. Noon e Yukihiko Nose. "In-vivo studies of reflectance pulse oximeter sensor". In OE/LASE'93: Optics, Electro-Optics, & Laser Applications in Science& Engineering, editado por Randall L. Barbour e Mark J. Carvlin. SPIE, 1993. http://dx.doi.org/10.1117/12.151190.

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Solgaard, Olav. "Fiber Optic Acoustic Sensors for In-vivo Studies". In Frontiers in Optics. Washington, D.C.: OSA, 2015. http://dx.doi.org/10.1364/fio.2015.fth2e.4.

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Sun, Chi-Kuang. "Harmonic optical microscopy for noninvasive in vivo embryonic studies". In Frontiers in Optics. Washington, D.C.: OSA, 2004. http://dx.doi.org/10.1364/fio.2004.fwn3.

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Kadjo, A., N. Baxan, A. Briguet, D. Graveron-Demilly, L. Fakri-Bouchet, R. Cespuglio e C. Rousset. "In vivo animal NMR studies using implantable micro coil". In 2008 IEEE International Workshop on Imaging Systems and Techniques (IST). IEEE, 2008. http://dx.doi.org/10.1109/ist.2008.4659987.

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Jakovljevic, Marko, Shalki Kumar, Lily Kuo e Gregg E. Trahey. "Transcostal imaging with large coherent apertures: Ex vivo studies". In 2014 IEEE International Ultrasonics Symposium (IUS). IEEE, 2014. http://dx.doi.org/10.1109/ultsym.2014.0421.

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Relatórios de organizações sobre o assunto "In vivo studies"

Cook, David Nelson. Studies of DNA supercoiling in vivo and in vitro. Office of Scientific and Technical Information (OSTI), outubro de 1990. http://dx.doi.org/10.2172/10191743.

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Cook, D. N. Studies of DNA supercoiling in vivo and in vitro. Office of Scientific and Technical Information (OSTI), outubro de 1990. http://dx.doi.org/10.2172/6993672.

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Clark, Douglas S. Response of Breast Cancer Cells to Hormonal Therapy; Quantitative in Vivo NMR Studies. Fort Belvoir, VA: Defense Technical Information Center, setembro de 1999. http://dx.doi.org/10.21236/ada391106.

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Bodo, Michael, Frederick J. Pearce e Matthew Sowd. In Vitro and In Vivo Studies for a Bio-Impedance Vital-Sign Monitor. Fort Belvoir, VA: Defense Technical Information Center, outubro de 2006. http://dx.doi.org/10.21236/ada460555.

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Liu, Hongliang, e Qianyun Pang. Lidocaine and oncologic outcomes—a systematic review from in vivo animal studies and clinical trials. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, abril de 2022. http://dx.doi.org/10.37766/inplasy2022.4.0161.

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Schuster, Gadi, e David Stern. Integrated Studies of Chloroplast Ribonucleases. United States Department of Agriculture, setembro de 2011. http://dx.doi.org/10.32747/2011.7697125.bard.

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Gene regulation at the RNA level encompasses multiple mechanisms in prokaryotes and eukaryotes, including splicing, editing, endo- and exonucleolytic cleavage, and various phenomena related to small or interfering RNAs. Ribonucleases are key players in nearly all of these post-transcriptional mechanisms, as the catalytic agents. This proposal continued BARD-funded research into ribonuclease activities in the chloroplast, where RNase mutation or deficiency can cause metabolic defects and is often associated with plant chlorosis, embryo or seedling lethality, and/or failure to tolerate nutrient stress. The first objective of this proposal was to examined a series of point mutations in the PNPase enzyme of Arabidopsis both in vivo and in vitro. This goal is related to structure-function analysis of an enzyme whose importance in many cellular processes in prokaryotes and eukaryotes has only begun to be uncovered. PNPase substrates are mostly generated by endonucleolytic cleavages for which the catalytic enzymes remain poorly described. The second objective of the proposal was to examine two candidate enzymes, RNase E and RNase J. RNase E is well-described in bacteria but its function in plants was still unknown. We hypothesized it catalyzes endonucleolytic cleavages in both RNA maturation and decay. RNase J was recently discovered in bacteria but like RNase E, its function in plants had yet to be explored. The results of this work are described in the scientific manuscripts attached to this report. We have completed the first objective of characterizing in detail TILLING mutants of PNPase Arabidopsis plants and in parallel introducing the same amino acids changes in the protein and characterize the properties of the modified proteins in vitro. This study defined the roles for both RNase PH core domains in polyadenylation, RNA 3’-end maturation and intron degradation. The results are described in the collaborative scientific manuscript (Germain et al 2011). The second part of the project aimed at the characterization of the two endoribonucleases, RNase E and RNase J, also in this case, in vivo and in vitro. Our results described the limited role of RNase E as compared to the pronounced one of RNase J in the elimination of antisense transcripts in the chloroplast (Schein et al 2008; Sharwood et al 2011). In addition, we characterized polyadenylation in the chloroplast of the green alga Chlamydomonas reinhardtii, and in Arabidopsis (Zimmer et al 2009). Our long term collaboration enabling in vivo and in vitro analysis, capturing the expertise of the two collaborating laboratories, has resulted in a biologically significant correlation of biochemical and in planta results for conserved and indispensable ribonucleases. These new insights into chloroplast gene regulation will ultimately support plant improvement for agriculture.

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Azem, Abdussalam, George Lorimer e Adina Breiman. Molecular and in vivo Functions of the Chloroplast Chaperonins. United States Department of Agriculture, junho de 2011. http://dx.doi.org/10.32747/2011.7697111.bard.

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We present here the final report for our research project entitled "The molecular and in vivo functions of the chloroplast chaperonins”. Over the past few decades, intensive investigation of the bacterial GroELS system has led to a basic understanding of how chaperonins refold denatured proteins. However, the parallel is limited in its relevance to plant chaperonins, since the plant system differs from GroEL in genetic complexity, physiological roles of the chaperonins and precise molecular structure. Due to the importance of plant chaperonins for chloroplast biogenesis and Rubisco assembly, research on this topic will have implications for many vital applicative fields such as crop hardiness and efficiency of plant growth as well as the production of alternative energy sources. In this study, we set out to investigate the structure and function of chloroplast chaperonins from A. thaliana. Most plants harbor multiple genes for chaperonin proteins, making analysis of plant chaperonin systems more complicated than the GroEL-GroES system. We decided to focus on the chaperonins from A. thaliana since the genome of this plant has been well defined and many materials are available which can help facilitate studies using this system. Our proposal put forward a number of goals including cloning, purification, and characterization of the chloroplast cpn60 subunits, antibody preparation, gene expression patterns, in vivo analysis of oligomer composition, preparation and characterization of plant deletion mutants, identification of substrate proteins and biophysical studies. In this report, we describe the progress we have made in understanding the structure and function of chloroplast chaperonins in each of these categories.

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Chan, Richard, e William J. Muller. In Vivo Structure-Function Studies on the Precise Role of ErbB-2 Signaling in Mammary Gland Development. Fort Belvoir, VA: Defense Technical Information Center, outubro de 2002. http://dx.doi.org/10.21236/ada411346.

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