Literatura científica selecionada sobre o tema "Ko Kong"

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Artigos de revistas sobre o assunto "Ko Kong"

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Bahrij, John, e Lily Ko. "An overview of English Resources for Chinese Legal Research". Legal Information Management 13, n.º 1 (março de 2013): 25–40. http://dx.doi.org/10.1017/s1472669613000078.

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AbstractThis article, written by John Bahrij and Lily Ko, focuses on resources in print and electronic form that are available in English for Chinese legal research in the Greater China region. The article covers resources for the People's Republic of China (PRC), Hong Kong Special Administrative Region (HKSAR), Macau Special Administrative Region (MSAR) and Taiwan. An overview of each jurisdictions legal system is also provided so that the resources can be discussed in the context of the prevailing system of law.
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Li, Jian, Josephine Mun-Yee Ko, Wei Dai, Valen Zhuoyou Yu, Hoi Yan Ng, Jean-Sébastien Hoffmann e Maria Li Lung. "Depletion of DNA Polymerase Theta Inhibits Tumor Growth and Promotes Genome Instability through the cGAS-STING-ISG Pathway in Esophageal Squamous Cell Carcinoma". Cancers 13, n.º 13 (26 de junho de 2021): 3204. http://dx.doi.org/10.3390/cancers13133204.

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Overexpression of the specialized DNA polymerase theta (POLQ) is frequent in breast, colon and lung cancers and has been correlated with unfavorable clinical outcomes. Here, we aimed to determine the importance and functional role of POLQ in esophageal squamous cell carcinoma (ESCC). Integrated analysis of four RNA-seq datasets showed POLQ was predominantly upregulated in ESCC tumors. High expression of POLQ was also observed in a cohort of 25 Hong Kong ESCC patients and negatively correlated with ESCC patient survival. POLQ knockout (KO) ESCC cells were sensitized to multiple genotoxic agents. Both rH2AX foci staining and the comet assay indicated a higher level of genomic instability in POLQ-depleted cells. Double KO of POLQ and FANCD2, known to promote POLQ recruitment at sites of damage, significantly impaired cell proliferation both in vitro and in vivo, as compared to either single POLQ or FANCD2 KOs. A significantly increased number of micronuclei was observed in POLQ and/or FANCD2 KO ESCC cells. Loss of POLQ and/or FANCD2 also resulted in the activation of cGAS and upregulation of interferon-stimulated genes (ISGs). Our results suggest that high abundance of POLQ in ESCC contributes to the malignant phenotype through genome instability and activation of the cGAS pathway.
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Boonwanno, Thanida. "Ethnogenèse des Thaïs-Ko-Kong : une « ethnie-frontières » dans un espace transfrontalier. Hommage à Jean Baffie, mon achan". Moussons, n.º 31 (31 de maio de 2018): 93–116. http://dx.doi.org/10.4000/moussons.4125.

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Mançanares, A. C. F., J. O. Manríquez, J. Cabezas, F. Telleria, L. Rodriguez e F. O. Castro. "185 Overexpression or CRISPr/Cas9-mediated inhibition of prostaglandin E2 receptors EP2 and EP4 in equine adipose mesenchymal stem cells: implications for cell migration and cellular therapies". Reproduction, Fertility and Development 31, n.º 1 (2019): 217. http://dx.doi.org/10.1071/rdv31n1ab185.

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Prostaglandin E2 (PGE2) acts through 4 cellular receptors: EP1, EP2, EP3, and EP4; only EP2 and EP4 are relevant for immunomodulation and migration in immune cells. Besides those, several cells express these receptors on their surface, including mesenchymal stem cells. Pharmacological inhibition of the EP2 receptor prevents migration of immune system cells to inflamed sites, where the concentration of PGE2 is high. Based on this, we hypothesised that overexpression of EP2 or EP4 receptors in equine mesenchymal stem cells (eMSC) will improve their migration to inflammatory sites and subsequent homing capability. Conversely, their suppression will lead to low or no migration, favouring the paracrine properties of MSC in the processes of tissue regeneration and reduction of inflammation. To test this, we manipulated the PGE2-EP2-EP4 axis and evaluated the effect of such modifications on transgenic cells in vitro. Equine MSC from adipose tissue were obtained from 5 animals. The coding sequences of both receptors were synthesised (GenScript, Hong Kong) based on the published horse genome (National Center for Biotechnology Information; https://www.ncbi.nlm.nih.gov/) and cloned into pcDNA3.1 overexpression vectors (Addgene). The resulting constructs were lipofected into naïve adipose eMSC. For knockouts, we PCR-amplified and sequenced horse EP2 and EP4 receptors, and gRNAs were created based on the obtained sequences and ligated into LentiCRISPRV2 plasmid (Addgene, Cambridge, MA, USA). The lentiviral vector plus helping packaging plasmids were co-transfected into HEK293FT cells and the produced viral particles were harvested and transduced into adipose eMSC. After 48h of transfection (for overexpression) or transduction (for knockout, KO), cells were probed for the presence/absence of EP2 and EP4 receptors by immunohistochemistry and/or quantitative (q)PCR. Mitomycin-C-treated cells of both phenotypes and naïve, were subjected to migration in scratch assay, towards 3mM PGE2. Fetal calf serum (10 or 0%) was used as positive or negative control, respectively, in migration experiments. Receptors EP2 and EP4 were clearly overexpressed after transfection as determined by immunocytochemistry or qPCR assays (phenotype MSC-EP2+/EP4+), whereas in the cells that underwent KO, little or no expression of EP2 and EP4 was detected (phenotype MSC-EP2ko/EP4ko) compared with unmanipulated cells (naïve MSC-Ctr). In the migration experiments towards 3mM of PGE2, MSC-EP2+/EP4+ cells at 24h filled the scratch faster (P<0.05) than MSC-EP2ko/EP4ko or MSC-Ctr. These results showed that manipulation of PGE2-EP2/EP4 axis receptors led to changes in cell surface receptor availability and increased the migration pattern in overexpressed cells compared with KO and unmanipulated cells. These factors may affect the design of cellular therapeutic tools for inflammatory diseases in the equine species. This research was supported by FONDECYT 3170390 to ACFM, Ministry of Education, Chile.
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Fernández-Ávila, D. G., D. Rincón-Riaño e J. Gutiérrez. "THU0467 CONCEPTS AND PERCEPTIONS ABOUT FIBROMYALGIA DIAGNOSIS, MONITORING AND TREATMENT AMONG COLOMBIAN RHEUMATOLOGISTS, PHYSIATRIST AND PAIN PHYSICIAN". Annals of the Rheumatic Diseases 79, Suppl 1 (junho de 2020): 470.1–471. http://dx.doi.org/10.1136/annrheumdis-2020-eular.5213.

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Background:Fibromyalgia is a chronic disease characterized by the presence of widespread and persistent musculoskeletal pain associated with a variety of symptoms. The concepts and perceptions around diagnosis and treatment of fibromyalgia among physicians are not objectively known. The purpose of this study is to obtain objective data through a survey and describe the concepts and perceptions about the diagnosis, treatment and treatment of fibromyalgia among colombian rheumatologists, physiatrist and pain physiciansObjectives:The main purpose of this study is to obtain objective data on this subject and describe the concepts and perceptions about the diagnosis, treatment and monitoring of FM among colombian rheumatologists, physiatrist and pain physicians.Methods:Cross-sectional study. Through a focus group in which two rheumatologists and one expert in qualitative research methods participated, a survey was designed to evaluated the perceptions and concepts that rheumatologists, physiatrist and pain physicians have on the diagnosis and treatment of fibromyalgia. The survey was self-applied anonymously through the internet.Results:Survey applied to 139 rheumatologists, 99 physiatrist and 81 pain physicians. 35 rheumatologists (25.2 %), 17 physiatrist (17.1 %) and 58 pain physicians (71.6 %) consider that there is not enough evidence to recognize fibromyalgia as a disease. 45 rheumatologists (32.4 %), 86 physiatrist (86 %) and 73 pain physicians (90.1 %) consider that the 1990 ACR (American college of Rheumatology) criteria are not sufficient to diagnose fibromyalgia, despite the fact more than 90% of them use the criteria as a tool to approach the diagnosis when suspecting fibromyalgia. The most formulated medications for managing fibromyalgia are antidepressants and is used by more than 80% of the respondents, followed by antiepileptics in pain physician (88.9%) but less than physiatrists and rheumatologists (66.6 % and 64.7 % respectively), and analgesic much more for pain physician and physiatry and less for rheumatologists (84 %, 75.7 % and 26.6 % respectively). All respondents consider that the patient with fibromyalgia should have a multidisciplinary approach. Most doctors of the three specialties believe that physiatrist should be the leaders of interdisciplinary management in the treatment of fibromyalgia patients.Conclusion:We present objective information on the perceptions of fibromyalgia among a group of Colombian rheumatologists, physiatrist and pain physician, documenting a frequent use of the ACR 1990 classification criteria. As regards treatment, a high percentage use of antidepressants and antiepileptic. Most believe that physiatrist should be the leaders of interdisciplinary management in the treatment of fibromyalgia patients.References:[1]Mu R, Li C, Zhu J-X, Zhang X-Y, Duan T-J, Feng M, et al. National survey of knowledge, attitude and practice of fibromyalgia among rheumatologists in China. Int J Rheum Dis. 2013;16:258–63.[2]Arshad A, Kong KO. Awareness and perceptions of fibromyalgia syndrome: a survey of Malaysian and Singaporean rheumatologists. Singapore Med J. 2007;48:25–30.[3]Arshad A, Kong KO, Ooi KK. Awareness and perceptions of fibromyalgia syndrome: a survey of southeast asian rheumatologists. J Clin Rheumatol. 2007;13:59–62.[4]Bloom S, Ablin JN, Lebel D, Rath E, Faran Y, Daphna-Tekoah S, et al. Awareness of diagnostic and clinical features of fibromyalgia among orthopedic surgeons. Rheumatol Int. 2013;33:927–31.[5]Clark P, Paiva ES, Ginovker A, Salomón PA. A patient and physician survey of fibromyalgia across Latin America and Europe. BMC Musculoskelet Disord. 2013;14:188.Disclosure of Interests: :None declared
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Muršak, Janko. "Andragogika kot "trojanski konj" pedagogike?" Andragoška spoznanja 6, n.º 3 (1 de dezembro de 2000): 3–5. http://dx.doi.org/10.4312/as.6.3.3-5.

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Ko sem bil še študent pedagogike, v tistem času edine, bolj ali manj monopolne znanosti, ki se je ukvarjala z vprašanji izobraževanja, je v nekem na pol resnem pogovoru tedanji vodilni pedagog dr. V. Schmidt označil andragogiko kot »trojanskega konja pedagogike«. To je bilo v času, ko se je andragogika borila za svoje mesto v okviru študija pedagogike.
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7

Ji, Z., L. Ma, L. Zhang, L. Ma, D. Liu, Y. Sun, X. Kong et al. "AB1244 PROGNOSTIC FACTORS IN IGG4-RELATED DISEASE: A LONG-TERM MONOCENTRIC CHINESE COHORT STUDY". Annals of the Rheumatic Diseases 79, Suppl 1 (junho de 2020): 1913.2–1914. http://dx.doi.org/10.1136/annrheumdis-2020-eular.4005.

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Background:Through initial response to treatment with GC, the patients with IgG4-related disease (IgG4-RD) exhibited high relapse rate after reduction or withdrawal of GC treatment, indicated the unsatisfactory prognosis for IgG4-RD. It is of clinical significance to develop new informative risk factors for refractory and relapsed disease.Objectives:To evaluate the prognosis of IgG4-RD and identify predictive factors for treatment resistance and disease relapse in a Chinese cohort.Methods:102 patients newly diagnosed with IgG4-RD were followed for 6-111 months. Clinical data were compared between patients whose disease went into remission and those who suffered refractory or relapsed disease. Predictive factors for refractory and relapsed disease were calculated by univariate analysis.Results:Among the 78 patients who received medical treatment with regular follow-up, 55 (59.8%) patients sustained clinical remission, and 23 (25%) patients suffered refractory or relapsed disease. The mortality and incidence of malignancy were both 4.35% during follow-up. Serum TNF-α ≥ 13 pg/ml, sIL-2R ≥ 1010 pg/ml, TC < 3.55 mmol/L, LDL < 2.0 mmol/L, IgG > 20.2 g/L, GC withdrawal, and treatment without immunosuppressor (IM) during the maintenance period (OR 3.23) were predictive factors for refractory and relapsed IgG4-RD. The combination of GC and IM treatment was protective (OR 0.338) against refractory and relapsed IgG4-RD.Conclusion:Serum TNF-α, sIL-2R, LDL, TC, IgG, GC withdrawal, and treatment without IM during the maintenance period were predictive factors for refractory and relapsed IgG4-RD. Treatment with GC and IM may protect against refractory and relapsed IgG4-RD.References:[1]Takahashi H, Yamamoto M, Suzuki C, Naishiro Y, Shinomura Y, Imai K. The birthday of a new syndrome: IgG4-related diseases constitute a clinical entity. Autoimmun Rev. 2010, 9: 591-4.[2]Lian L, Wang C, Tian JL. IgG4-related retroperitoneal fibrosis: a newly characterized disease. Int J Rheum Dis. 2016, 19: 1049-55.[3]Li PH, Ko KL, Ho CT, Lau LL, Tsang RK, Cheung TT, et al. Immunoglobulin G4-related disease in Hong Kong: clinical features, treatment practices, and its association with multisystem disease. Hong Kong Med J. 2017, 23: 446-53.[4]Culver EL, Sadler R, Bateman AC, Makuch M, Cargill T, Ferry B, et al. Increases in IgE, Eosinophils, and Mast Cells Can be Used in Diagnosis and to Predict Relapse of IgG4-Related Disease. Clin Gastroenterol Hepatol. 2017, 15: 1444-52.[5]Inoue D, Yoshida K, Yoneda N, Ozaki K, Matsubara T, Nagai K, et al. IgG4-related disease: dataset of 235 consecutive patients. Medicine (Baltimore). 2015, 94: e680.[6]Brito-Zeron P, Kostov B, Bosch X, Acar-Denizli N, Ramos-Casals M, Stone JH. Therapeutic approach to IgG4-related disease: A systematic review. Medicine (Baltimore). 2016, 95: e4002.[7]Peng Y, Li JQ, Zhang PP, Zhang X, Peng LY, Chen H, et al. Clinical outcomes and predictive relapse factors of IgG4-related disease following treatment: a long-term cohort study. J Intern Med. 2019.Acknowledgments:This work was supported by the National Natural Science Foundation of China (NSFC 81601398; NSFC 81771730); the Animal Research Project of Shanghai Science and Technology Commission (grant number 17140902000); and Shanghai Pujiang Rheumatologists Training Program (SPROG201801)Disclosure of Interests:None declared
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8

Gimpel, Denise. "Max Ko-wu HUANG. The Meaning of Freedom: Yan Fu and the Origins of Chinese Liberalism. With A Foreword by Thomas A. Metzger. Hong Kong: Chinese University Press, 2008. xxiv + 408 pp. ISBN: 978-962-996-278-4 (hbk). $55." Journal of the Economic and Social History of the Orient 54, n.º 4 (2011): 580–83. http://dx.doi.org/10.1163/156852011x611490.

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Livij, Tit. "Galci zavzamejo Rim. Druga ustanovitev mesta (386). Zgodovina Rima, 5.37.4–55.5 (prevedel Primož Simoniti)". Keria: Studia Latina et Graeca 16, n.º 1 (24 de julho de 2014): 111. http://dx.doi.org/10.4312/keria.16.1.111-125.

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37 […] Ko so Galci medtem izvedeli, da so kršitelji medčloveškega prava poželi časti, njihovo odposlanstvo pa posmeh, so podivjali od besa – to pleme pri tem ne pozna mere –, pri priči izdrli bojna znamenja in se v pospešenem pohodu odpravili na pot. Ko so se prestrašena mesta ob hrupu njihovega prehoda jadrno oborožila in je vanje pribežalo prebivalstvo s podeželja, so na vse grlo razglašali, da gredo nad Rim; povsod, koder so se valili, se je vojni pohod konj in mož razlival v dolžino in širino in zavzemal neznansko veliko prostora.
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Timpe, H. J. "Volker Ko�, Umweltchemie, Eine Einf�hrung f�r Studium und Praxis, 1. Auflage, 1997, 110 Abb., 74 Tab., 288 Seiten, gebunden DM 58,-, �S 423,40, sFr 53,-, GBP 22,50, US $ 36,25, Berlin-Heidelberg-New York-London-Paris-Tokyo-Hong Kong, Springer-Verlag, ISBN 3-540-61830-9". Journal f�r Praktische Chemie/Chemiker-Zeitung 340, n.º 5 (1998): 488–90. http://dx.doi.org/10.1002/prac.19983400519.

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Teses / dissertações sobre o assunto "Ko Kong"

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Boonwanno, Thanida. "Les Frontières d’une ethnie des frontières : Les Thaïs-Ko-Kong". Thesis, Aix-Marseille, 2014. http://www.theses.fr/2014AIXM3042.

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Les Thaïs dont il est question dans cette thèse ont été détachés et cédé avec l'ancien territoire siamois de Patchan Khirikhet ou Ko Kong à la colonie française du Cambodge en 1904. En conséquence, des Thaïs sont restés dans le territoire cambodgien de Ko Kong jusqu'à présent. À plusieurs époques, toutefois, les Thaïs-Ko-Kong ont choisi de traverser la frontière afin de rentrer définitivement dans la terre patrie de Thaïlande ; l'époque des Khmers Rouges tout particulièrement a provoqué la plus grande de ces immigrations et une nouvelle dispersion des Thaïs de Ko Kong. La majorité des immigrants thaïs-Ko-Kong a trouvé refuge dans le district de Khlong Yai, dans la province frontalière de Trat. Aujourd'hui, le district thaïlandais de Khlong Yai et la province cambodgienne de Ko Kong sont ainsi l'espace transfrontalier principal des Thaïs-Ko-Kong. Cette recherche a pour le but de répondre à trois questions principales sur l'ethnogenèse des Thaïs-Ko-Kong, les identités dynamiques des Thaïs-Ko-Kong et l'hégémonie des frontières des Thaïs-Ko-Kong. Les Thaïs-Ko-Kong ne sont pas un groupe ethnique, ils sont une « ethnie-frontières », un pseudo groupe ethnique, qui s'est formé par une histoire commune liée à la délimitation des frontières et par l'expérience des immigrations depuis le Cambodge
The Thai people studied in this research have been separated with the ancient Siamese territory of Patchan Khirikhet or Ko Kong and given to the French colony of Cambodia in 1904. Consequently, they constitute nowadays a Thai ethnic minority in Ko Kong province of Cambodia. From generation to generation, at many occasions the Thais of Ko Kong have decided to cross the borderline to go back to their ancestor's homeland. But the main immigration, the dispersion and the disappearance of many Thais from Ko Kong occurred during the Khmers Rouges period. A majority of the Thai migrants from Ko Kong province have settled down at Khlong Yai district at the extreme East of Trat province, in Thailand. At the present time, Khlong Yai district of Thailand and Ko Kong province of Cambodia are therefore a core trans-boundary area for the Thais of Ko Kong. The aims of this research are at answering three mains questions concerning the ethnogenesis, the dynamic identities of the Thais of Ko Kong and their hegemonic controls of the borderlines and border areas. The Thais of Ko Kong are not an ethnic group. They are an « border ethnic group », a pseudo-ethnic group, who have been formed by their common history of the delimitation of frontiers in 1904 and their migration experiences from Cambodia
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苗華培 e Wah-pui Edward Miu. "Rehabilitation centre at Cha Ko Ling". Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 1996. http://hub.hku.hk/bib/B31983005.

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Livros sobre o assunto "Ko Kong"

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Huang, Zhengping. Zui xin ko ji Ying Han dui zhao ji shui wu shui kong zhi gong cheng xue ci hui =: The English-Chinese terminology of water supply & wastewater control engineering. Taibei Xian: Wan ren chu ban she, 2002.

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2

Helu, I. F. Ko e tohi vete: 'o e ngaahi hiva, maau, ta'anga, langi, hiva kakala, etc. Konga 1. Nukulofa, Tonga: s.n., 2006.

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3

Peter, Lam, e Chinese University of Hong Kong. Art Gallery., eds. Tʻai ko chia chʻi: Tsan te lou chüan tseng tʻang ming kʻuan tzʻu chʻi. Hsiang-kang: Hsiang-kang Chung wen ta hsüeh wen wu kuan, 1993.

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4

Takashi, Nagai. Kono ko o nokoshite. 2015.

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Section, IEEE Hong Kong. Asp-Dac '99: Proceedings of the Asia and South Pacific Design Automation Conference January 18-21, 1999 Hong Kong Convention and Exhibition Centre Wanchai, Hong ko. Institute of Electrical & Electronics Enginee, 1999.

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Takimoto, Jokai. Kono ko ra to te o awasete. Hatsubaimoto Seiunsha, 1994.

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"Shōnen A" kono ko o unde--: Chichi to haha kaikon no shuki. Tōkyō: Bungei Shunjū, 1999.

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Shiba Ryotaro, "kono kuni" e no kotoba: Yukoku no hatsugen ko ("Cho" dokkai koza). Hatsubai Koara Bukkusu, 1996.

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Capítulos de livros sobre o assunto "Ko Kong"

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Wan, Eddie Cheah Kee, e Ferdaus Mohamat-Yusuff. "Contamination of Trace Elements (Cu, Pb, Cr) in Kong Ko Laut, Johor, Malaysia". In From Sources to Solution, 567–72. Singapore: Springer Singapore, 2013. http://dx.doi.org/10.1007/978-981-4560-70-2_101.

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Desser, David. "‘Crazed Heat’: Nakahira Ko and the Transnational Self-remake". In Transnational Film Remakes. Edinburgh University Press, 2017. http://dx.doi.org/10.3366/edinburgh/9781474407236.003.0011.

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Transnational film remakes present a variety of complicating issues – of geography, culture, translation, and temporality, among others. Directors have remade their own films, sometimes quite directly, other times by shifting genre, but the case of a director moving from one national situation to another and remaking an earlier film is rare. What makes such an auto-remake particularly interesting is that it calls into question issues of authorship. This chapter will look at the case of Nakahira Ko who made the influential Kurutta Kajitsu (Crazed Fruit,1956) and later in his career remade the film (under the Chinese pseudonym Yang Shu-hsi) as Kuang lian shi (Summer Heat, 1968). The case of Crazed Fruit and its transformation into Summer Heat is interesting, partly due to the stature of the Japanese original and also due to some of the more obvious transformations, such as from Ishihara Yujiro in the original to a more generic male star in the remake. More significantly, while Crazed Fruit was part of a cycle of Japanese films examining post-war disaffected youth, the Hong Kong remake is far less implicated in a cultural moment.
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