Bibliografias temáticas / Lactame

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Literatura científica selecionada sobre o tema "Lactame"

Autor: Grafiati
Publicado: 4 de junho de 2021
Última modificação: 7 de julho de 2024

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Artigos de revistas sobre o assunto "Lactame"

1

. AL-Kaisse, Asmaa A., Amina N. AL-Thwani e Rabab Q. AL-Segar. "PCR Detection of Some ESBLs (bla) Genes in Pseudomonas aeruginosa Isolated from Burn’s Units in Bagdad Hospitals". Journal of Biotechnology Research Center 9, n.º 2 (1 de junho de 2015): 74–80. http://dx.doi.org/10.24126/jobrc.2015.9.2.439.

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Multi drug resistant (MDR) and Extended Spectrum Beta Lactamase (ESBLs) of Pseudomonas aeruginosawere detected. Pseudomonas aeruginosa is a bacterium responsible for severe infections in burn’s units,plasmid DNA analysis and encoded many types of genes responsible for beta-lactamases. To determine thetype of genes responsible for beta-lactam broad spectrum in P. aeruginosa strains isolated from 100 swabsof burn’s units environment, using a molecular methods (PCR) by primers specific to ESBLs (bla ) genesoxacillin hydrolyzing capabilities OXA-10, OXA-4 and Vietnam Extended-Spectrum β-Lactame VEB-1.The results revealed that 15 strains were isolated from burn units environment. All of 15 (100%) werepositive OXA-10 and only one (6.6%) for OXA-4 while the other gene VEB-1 was found in 6 (40%) isolates.تم
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Sörgel, Fritz, Jürgen Bulitta e Cornelia Landersdorfer. "Pharmakokinetik und Pharmakodynamik der β-Lactame: Was wir über β-Lactame wissen und was wir wissen möchten". Pharmazie in unserer Zeit 35, n.º 5 (setembro de 2006): 438–51. http://dx.doi.org/10.1002/pauz.200600191.

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Wälchli, Rudolf, Stefan Bienz e Manfred Hesse. "Synthese macrocyclischer Lactame aus Ketonen durch Ringerweiterung". Helvetica Chimica Acta 68, n.º 2 (27 de março de 1985): 484–92. http://dx.doi.org/10.1002/hlca.19850680222.

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Wagner, Klaus, Georg Rudakoff e Peter Fröhlich. "Untersuchungen des Assoziationsverhaltens einiger Lactame in unpolaren Lösungsmitteln". Zeitschrift für Chemie 15, n.º 7 (1 de setembro de 2010): 272–75. http://dx.doi.org/10.1002/zfch.19750150710.

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Scharplaz, Madlaina. "Beta-Lactame – Als Standardtherapie zur Behandlung einer Pneumonie empfohlen". Praxis 94, n.º 41 (2005): 1607–8. http://dx.doi.org/10.1024/0369-8394.94.41.1607.

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Li, Lu, Qiyao Wang, Hui Zhang, Minjun Yang, Mazhar I. Khan e Xiaohui Zhou. "Sensor histidine kinase is a β-lactam receptor and induces resistance to β-lactam antibiotics". Proceedings of the National Academy of Sciences 113, n.º 6 (1 de fevereiro de 2016): 1648–53. http://dx.doi.org/10.1073/pnas.1520300113.

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β-Lactams disrupt bacterial cell wall synthesis, and these agents are the most widely used antibiotics. One of the principle mechanisms by which bacteria resist the action of β-lactams is by producing β-lactamases, enzymes that degrade β-lactams. In Gram-negative bacteria, production of β-lactamases is often induced in response to the antibiotic-associated damage to the cell wall. Here, we have identified a previously unidentified mechanism that governs β-lactamase production. In the Gram-negative enteric pathogenVibrio parahaemolyticus, we found a histidine kinase/response regulator pair (VbrK/VbrR) that controls expression of a β-lactamase. Mutants lacking either VbrK or VbrR do not produce the β-lactamase and are no longer resistant to β-lactam antibiotics. Notably, VbrK autophosphorylation is activated by β-lactam antibiotics, but not by other lactams. However, single amino acid substitutions in the putative periplasmic binding pocket of VbrK leads its phosphorylation in response to both β-lactam and other lactams, suggesting that this kinase is a β-lactam receptor that can directly detect β-lactam antibiotics instead of detecting the damage to cell wall resulting from β-lactams. In strong support of this idea, we found that purified periplasmic sensor domain of VbrK binds penicillin, and that such binding is critical for VbrK autophosphorylation and β-lactamase production. Direct recognition of β-lactam antibiotics by a histidine kinase receptor may represent an evolutionarily favorable mechanism to defend against β-lactam antibiotics.
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Ambrosi, Horst-Dieter, Annamarie Kunath e Klaus Jähnisch. "β-Lactame und β-Lactam-Zwischenprodukte, 2. Mitt.: Stereoselektive Synthese voncis-3-Amino-1,4-diphenyl-azetidin-2-on". Archiv der Pharmazie 326, n.º 6 (1993): 319–21. http://dx.doi.org/10.1002/ardp.19933260603.

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Leygue, N., C. Picard, P. Tisnes e L. Cazaux. "Macrocyclisation en series lactone, thiolactone et lactame à motif ethylenedioxy". Tetrahedron 44, n.º 18 (janeiro de 1988): 5845–56. http://dx.doi.org/10.1016/s0040-4020(01)81441-1.

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Diederich, Michel, e Udo Nubbemeyer. "Synthese optisch aktiver neungliedriger Lactame durch zwitterionische Aza-Claisen-Reaktion". Angewandte Chemie 107, n.º 9 (2 de maio de 1995): 1095–98. http://dx.doi.org/10.1002/ange.19951070916.

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Langhals, Heinz, Reda El-Shishtawy, Petra von Unold e Maximilian Rauscher. "Methoxyperylene Bisimides and Perylene Lactame Imides: Novel, Red Fluorescent Dyes". Chemistry - A European Journal 12, n.º 17 (2 de junho de 2006): 4642–45. http://dx.doi.org/10.1002/chem.200501439.

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Teses / dissertações sobre o assunto "Lactame"

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Krelaus, Ralf. "Synthese von bicyclischen Lactamen durch Ugi-Reaktion und Ringschlussmetathese". [S.l. : s.n.], 2003. http://deposit.ddb.de/cgi-bin/dokserv?idn=968549772.

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Zhang, Hailong. "Scandium-catalyzed atom-economical reactions for C-O and C-C bond formations". Electronic Thesis or Diss., université Paris-Saclay, 2024. http://www.theses.fr/2024UPASF007.

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Ce travail de thèse s’est focalisé sur la formation de liaison carbone-oxygène et carbone-carbone via des réactions à économie d’atomes catalysées par des complexes de scandium. Après une introduction générale sur le scandium et ses propriétés physico-chimiques, une description détaillée du triflate de scandium (Sc(OTf)₃) met en lumière ses propriétés acides de Lewis et son utilisation en catalyse dans diverses transformations de formation de liaisons carbone-carbone telles les réactions d'aldolisation ou de Michael. Dans le premier chapitre, la cyclisation d'acides δ/ε-alcénoïques et des δ-alcénamides N-protégés catalysée par Sc(OTf)₃ en conditions thermiques ou par activation micro-ondes a été développée pour préparer, pour la première fois, des γ/δ-lactones et des γ/δ-lactames. Au cours de cette étude, la diversité moléculaire qui peut être atteinte par l’utilisation du triflate de scandium en catalyse a pu être mise en évidence. Il a aussi été montré que la sélectivité de la transformation des acides δ/ε-alcénoïques est directement corrélée aux motifs de substitution de la chaîne du squelette alkyle et de la partie alcénique. Dans la plupart des cas, la formation de γ- ou de δ-lactones est observée avec de bons rendements et de hautes régiosélectivités. Toutefois, lorsque le squelette des acides δ/ε-alkénoïques porte des groupements phényles riches en électrons en position géminale, une cyclisation de type Friedel-Crafts entre l’un de ces deux groupements et l’oléfine se produit exclusivement avec des rendements élevés. La réaction d'hydrofonctionnalisation des δ-alcénamides N-protégés catalysée par Sc(OTf)₃ procède via une cyclisation O-sélective originale et rarement rapportée, soit totale soit de manière préférentielle. Dans le second chapitre, de nouveaux complexes de scandium β-dicétiminates de structures bien définies ont été synthétisés et caractérisés notamment par spectroscopie par diffraction des rayon-X. Le potentiel de ces complexes comme catalyseurs a été étudié dans la réaction d’alkylation C(sp²)-H des anilines avec des dérivés styrèniques et des dérivés α-méthylstyrèniques. Au départ des dérivés styréniques, une réaction d’alkylation ortho-sélective conduisant au produit ramifié est observée avec de bons à d’excellents rendements. Elle tolère non seulement une large gamme de dérivés aniliniques mais est également compatible avec certains alcènes non-activés tels que le norbornène et le 1,3-cyclohexadiène. De plus, la réaction peut être menée à l'échelle du gramme avec une faible charge catalytique sans changement notable de l'activité catalytique. Au départ des dérivés α-méthylstyrènes, des produits d’alkylation ramifiés substitués en position para ont été obtenus avec de bons rendements. Enfin, des informations sur le mécanisme ont été collectées à l’aide d’études cinétiques, d’expériences de marquage au deutérium, de synthèses d’intermédiaires réactionnels et d’expériences de contrôle ou compétitives. Des premiers essais de développement d’une version asymétrique de cette transformation ont aussi été menés par l’emploi de complexes de scandium chiraux énantiopurs
This PhD work focused on the formation of carbon-oxygen and carbon-carbon bonds via atom-economical reactions catalysed by scandium complexes. After a general introduction to scandium and its physico-chemical properties, a detailed description of scandium triflate (Sc(OTf)₃) highlights its Lewis acid properties and its use as a catalyst in various carbon-carbon bond-forming transformations such as aldol or Michael reactions. In the first chapter, the cyclisation of N-protected δ/ε-alkenoic acids and δ-alkenamides catalysed by Sc(OTf)₃ under thermal conditions or microwave activation was developed to prepare, for the first time, γ/δ-lactones and γ/δ-lactams. In the course of this study, the molecular diversity that can be achieved by using scandium triflate in catalysis was highlighted. It was also shown that the selectivity of the transformation of δ/ε-alkenoic acids is directly correlated to the substitution patterns of the alkyl backbone chain and the alkene moiety. In most cases, the formation of γ- or δ-lactones is observed with good yields and high regioselectivities. However, when the δ/ε-alkenoic acid backbone bears electron-rich phenyl groups in the geminal position, Friedel-Crafts-type cyclisation between one of these two groups and the olefin occurs exclusively in high yields. The Sc(OTf)₃-catalysed hydrofunctionalisation reaction of N-protected δ-alkenamides proceeds preferentially or exclusively via an original and rarely reported O-selective cyclisation. In the second chapter, novel well-defined β-diketiminate scandium complexes were synthesized and characterized in particular by X-ray diffraction spectroscopy. The potential of these complexes as catalysts was investigated in the C(sp²)-H alkylation reaction of anilines with styrene and α-methylstyrene derivatives. Starting from styrenes derivatives, an ortho-selective alkylation reaction leading to the branched product is observed with good-to-excellent yields. The reaction tolerates a wide range of aniline derivatives and is compatible with certain non-activated alkenes such as norbornene and 1,3-cyclohexadiene. Furthermore, the reaction can be carried out on a gram scale with a low catalyst loading without any noticeable change in catalytic activity. Starting from α-methylstyrene derivatives, branched alkylation products substituted at the para-position were obtained in good yields. Finally, mechanistic information was gathered using kinetic studies, deuterium labelling experiments, synthesis of reaction intermediates and control or competitive experiments. Initial attempts were also made to develop an asymmetric version of this transformation using chiral enantiopure scandium complexes
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Freitag, Dirk. "Die Synthese von [beta]-Lactam-Sulfonamid-Hybriden [beta-Lactam-Sulfonamid-Hybriden] : neue Aspekte der katalytischen ring-schliessenden Metathese beim Aufbau von Heterobicyclen und Studien zur intramolekularen [2+2]-Olefin-Isocyanat-Cycloaddition /". Dresden : TUDpress, 2005. http://deposit.ddb.de/cgi-bin/dokserv?id=2671906&prov=M&dok_var=1&dok_ext=htm.

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4

Henlin, Jean-Michel. "Approches synthétiques d'antibiotiques potentiels de type β-lactame". Mulhouse, 1986. http://www.theses.fr/1986MULH0021.

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A partir de diazépine-1,2carboxylates-1 et de cétènes ou de chlorures d'acide, synthèse d'aza-3carbapérames et aza-3carbapénèmes-1 par l'intermédiaire d'azeto (1,2-b) diazépines-1,2 (a); additions de diels alder de a et de nitrosoformyl benzène : obtention d'oxo-4 benzamido-3 (dihydro oxazine-1,2yl-6)-2 azétidinecarbamates-1
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5

Couloigner, Evanne. "Synthese de composes du type -lactame : antibiotiques potentiels ?" Brest, 1999. http://www.theses.fr/1999BRES2028.

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Une des facons de lutter contre la resistance bacterienne est de modifier le cycle -lactame. La modelisation moleculaire laisse a penser que les composes du type -lactame peuvent remplacer les -lactamines dans l'activite qu'elles exercent sur les plp, proteines liant la penicilline, impliquees dans la formation de la paroi des bacteries et particulierement dans la derniere etape de la synthese du peptidoglycane. La synthese de composes du type -lactame possedant des groupements electroattracteurs lies a l'azote du cycle lactame ainsi qu'a la fonction amine de la chaine laterale a constitue l'objectif de ce travail. Cette fonctionnalisation des molecules permet d'accroitre la reactivite des composes et en particulier celle de la liaison c-n du cycle vis a vis de l'acylation par les plp, ce qui se traduit par une meilleure activite antibacterienne. Dans ce contexte, des pyrazolidinones monocycliques notamment n-sulfonees, d'une structure voisine de l'aztreoname, ont ete synthetisees. Des pyrrolidinones ont egalement ete realisees et leur activite biologique a ete comparee avec celle de la lactivicine et d'analogues decrits dans la litterature. La liaison amide du cycle -lactame a aussi ete activee par une deuxieme fonction carbonyle, ce qui permet d'obtenir des composes du type imides susceptibles de posseder une activite antibacterienne accrue. Ces differentes molecules ont ete testees sur les bacteries staphylococcus aureus, escherichia coli et micrococcus luteus. Certains de ces composes ont une activite biologique moderee ou interessante ce qui suggere le developpement de travaux ulterieurs.
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LEYGUE, ESTREME NADINE. "Macrocylisation en series lactame, lactone et thiolactone : mise en evidence d'un tetralactame comme complexant selectif du calcium". Toulouse 3, 1987. http://www.theses.fr/1987TOU30124.

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Leygue, Nadine. "Macrocyclisation en séries lactame, lactone et thiolactone mise en évidence d'un tétralactame comme complexant sélectif du calcium /". Grenoble 2 : ANRT, 1987. http://catalogue.bnf.fr/ark:/12148/cb376073973.

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8

Albrecht, Dominik. "Stereoselektive intramolekulare [2+2]-Photocycloadditionen alpha, beta-ungesättigter Lactame /". München : Verl. Dr. Hut, 2009. http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&doc_number=017356085&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA.

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9

Staub, Isabell Helga. "β-Lactame und ihre enzymatischen Angriffsziele in multiresistenten Bakterien". Diss., lmu, 2011. http://nbn-resolving.de/urn:nbn:de:bvb:19-136910.

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Voss, Felix Henning Tilmann [Verfasser]. "Bifunktionelle Oxidationskatalysatoren durch Ligation an chirale Lactame / Felix Voss". München : Verlag Dr. Hut, 2010. http://d-nb.info/1009095552/34.

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Livros sobre o assunto "Lactame"

1

Ogliaruso, Michael A. Synthesis of lactones and lactams. Chichester: Wiley, 1993.

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2

Bellido, F. The new -lactams: Mode of action, mechanisms of resistance. Basle, Switzerland: Roche, 1989.

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3

Hamao, Umezawa, Takeda Kagaku Shinkō Zaidan e Takeda Science Foundation Symposium (4th : 1986 : Kyoto, Japan), eds. Frontiers of antibiotic research. Tokyo: Academic Press, 1987.

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4

Alcaide, B., e Bimal K. Banik. Heterocyclic scaffolds I: Ss-lactams. Heidelberg: Springer, 2010.

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5

Banik, Bimal K., ed. Beta-Lactams. Cham: Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-55621-5.

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Peter G. J. M. Janssen. Lactate threshold training. Champaign, IL: Human Kinetics, 2001.

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7

Rudolf, Puffr, e Kubánek Vladimír, eds. Lactam-based polyamides. Boca Raton: CRC Press, 1991.

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8

Janecki, Tomasz, ed. Natural Lactones and Lactams. Weinheim, Germany: Wiley-VCH Verlag GmbH & Co. KGaA, 2013. http://dx.doi.org/10.1002/9783527666911.

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Janssen, Peter. Training lactate pulse rate. Oulu, Finland: Polar Electro Oy, 1989.

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10

Page, Michael I., ed. The Chemistry of β-Lactams. Dordrecht: Springer Netherlands, 1992. http://dx.doi.org/10.1007/978-94-011-2928-2.

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Capítulos de livros sobre o assunto "Lactame"

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Fong, I. W. "New β-Lactam-β-Lactamase Inhibitor Combinations". In New Antimicrobials: For the Present and the Future, 39–57. Cham: Springer International Publishing, 2023. http://dx.doi.org/10.1007/978-3-031-26078-0_3.

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2

Schomburg, Dietmar, e Margit Salzmann. "Lactase". In Enzyme Handbook 4, 551–54. Berlin, Heidelberg: Springer Berlin Heidelberg, 1991. http://dx.doi.org/10.1007/978-3-642-84437-9_97.

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Bährle-Rapp, Marina. "lactate". In Springer Lexikon Kosmetik und Körperpflege, 308. Berlin, Heidelberg: Springer Berlin Heidelberg, 2007. http://dx.doi.org/10.1007/978-3-540-71095-0_5749.

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Poblete, Glenn Hernández, Maarten W. Nijsten e Jan Bakker. "Lactate". In Monitoring Tissue Perfusion in Shock, 131–42. Cham: Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-43130-7_9.

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Castro, Ricardo, David Carpio e Glenn Hernández. "Lactate". In Hemodynamic Monitoring, 191–201. Cham: Springer International Publishing, 2019. http://dx.doi.org/10.1007/978-3-319-69269-2_17.

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Stellmach, Bruno. "Lactase". In Bestimmungsmethoden Enzyme, 155–61. Heidelberg: Steinkopff, 1988. http://dx.doi.org/10.1007/978-3-642-93668-5_22.

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Gooch, Jan W. "Lactam". In Encyclopedic Dictionary of Polymers, 417. New York, NY: Springer New York, 2011. http://dx.doi.org/10.1007/978-1-4419-6247-8_6734.

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Arslantas, Mustafa Kemal, Tunc Asuroglu, Reyhan Arslantas, Emin Pashazade, Pelin Corman Dincer, Gulbin Tore Altun e Alper Kararmaz. "Using Machine Learning Methods to Predict the Lactate Trend of Sepsis Patients in the ICU". In Communications in Computer and Information Science, 3–16. Cham: Springer Nature Switzerland, 2024. http://dx.doi.org/10.1007/978-3-031-59091-7_1.

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AbstractSerum lactate levels are considered a biomarker of tissue hypoxia. In sepsis or septic shock patients, as suggested by The Surviving Sepsis Campaign, early lactate clearance-directed therapy is associated with decreased mortality; thus, serum lactate levels should be assessed. Monitoring a patient’s vital parameters and repetitive blood analysis may have deleterious effects on the patient and also bring an economic burden. Machine learning and trend analysis are gaining importance to overcome these issues. In this context, we aimed to investigate if a machine learning approach can predict lactate trends from non-invasive parameters of patients with sepsis. This retrospective study analyzed adult sepsis patients in the Medical Information Mart for Intensive Care IV (MIMIC-IV) dataset. Inclusion criteria were two or more lactate tests within 6 h of diagnosis, an ICU stay of at least 24 h, and a change of ≥1 mmol/liter in lactate level. Naïve Bayes, J48 Decision Tree, Logistic Regression, Random Forest, and Logistic Model Tree (LMT) classifiers were evaluated for lactate trend prediction. LMT algorithm outperformed other classifiers (AUC = 0.803; AUPRC = 0.921). J48 decision tree performed worse than the other methods when predicting constant trend. LMT algorithm with four features (heart rate, oxygen saturation, initial lactate, and time interval variables) achieved 0.80 in terms of AUC (AUPRC = 0.921). We can say that machine learning models that employ logistic regression architectures, i.e., LMT algorithm achieved good results in lactate trend prediction tasks, and it can be effectively used to assess the state of the patient, whether it is stable or improving.
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Bährle-Rapp, Marina. "Zinc Lactate". In Springer Lexikon Kosmetik und Körperpflege, 600. Berlin, Heidelberg: Springer Berlin Heidelberg, 2007. http://dx.doi.org/10.1007/978-3-540-71095-0_11313.

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Bährle-Rapp, Marina. "Butyl Lactate". In Springer Lexikon Kosmetik und Körperpflege, 79. Berlin, Heidelberg: Springer Berlin Heidelberg, 2007. http://dx.doi.org/10.1007/978-3-540-71095-0_1426.

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Trabalhos de conferências sobre o assunto "Lactame"

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Kovalenko, E. "LACTASE DEFICIENCY IN RUSSIA: MULTIETHNIC GENETIC STUDY". In I International Congress “The Latest Achievements of Medicine, Healthcare, and Health-Saving Technologies”. Kemerovo State University, 2023. http://dx.doi.org/10.21603/-i-ic-53.

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Adult lactase deficiency – the inability to effectively digest lactose in adulthood – causes digestive discomfort and may be associated with the elimination of a whole category of dairy products from the diet. The objective of the study was to assess the prevalence of the gene associated with lactose deficiency for a sample of 24 thousand people living in Russia. It turned out that among the studied population groups, the frequency of occurrence of the GG genotype in rs4988235 was higher than the average in European populations. In particular, the prevalence of the genotype of lactase deficiency in the group of Eastern Slavs was 42.8% (95% CI: 42.1–43.4%). The regional prevalence of lactase deficiency was also investigated depending on the place of residence.
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Vasić, Katja, Mateja Primožič, Mislav Trbušić, Viktor Goričan, Marko Jesenik, Anton Hamler, Željko Knez, Yilmaz Yürekli e Maja Leitgeb. "Magnetic Field as a Tool for Enhancing β -Lactamase Activity". In International Conference on Technologies & Business Models for Circular Economy. University of Maribor Press, 2024. http://dx.doi.org/10.18690/um.fkkt.1.2024.11.

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β-Lactam antibiotics have been extensively employed in bacterial treatment ever since penicillin's groundbreaking discovery. Despite the proliferation of antibiotics in the pharmaceutical sector today, bacteria often evolve defense mechanisms. Chief among these is the production of β-lactamase enzymes, which degrade β-lactam antibiotics, representing a prevalent form of antibiotic resistance. Additionally, these antibiotics exhibit limited biodegradability, with only 20% breaking down naturally. Hence, finding effective methods to mitigate the presence of β-lactam antibiotics is crucial in combating antibiotic pollution.
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Khan, A., e S. Chiu. "Sublimed Sulfur (SULMEDOL) for the Activation of Endogenous Lactase and Restoration of Lactose Tolerance". In Abstracts of the NHPRS – The 15th Annual Meeting of the Natural Health Products Research Society of Canada (NHPRS). Georg Thieme Verlag KG, 2018. http://dx.doi.org/10.1055/s-0038-1644933.

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Looijesteijn, Ellen, Lonneke JanssenDuijghuijsen, Maartje van den Belt, Beatrix Gerhard, Renata Ariens, Reina Tjoelker e Jan Geurts. "Daily Lactose Supplementation in Lactase Non-Persistent Individuals Induces Colonic Adaptation and Reduces Intolerance Symptoms". In European Nutrition Conference. Basel Switzerland: MDPI, 2023. http://dx.doi.org/10.3390/proceedings2023091047.

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Luo, Qijian, e Yiqi JIn. "Oral Beta-lactamase Protects the Gut Bifidobacterium/Lactobacillus from Beta-lactam Antibiotics-mediated Damage in SD Rats". In ICBBS '20: 2020 9th International Conference on Bioinformatics and Biomedical Science. New York, NY, USA: ACM, 2020. http://dx.doi.org/10.1145/3431943.3431948.

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Lavandeira Pérez, M., E. Martínez Ruiz, G. Casarrubios Lázaro, I. Mendoza Acosta, P. Tardaguila Molina, C. Dean Barahona, Á. Yuste Gutiérrez, M. Blanco Crespo, A. Lázaro López e AM Horta Hernández. "4CPS-249 Second generation β-lactam/β-lactamase inhibitor combinations: ceftazidime–avibactam and ceftolozane–tazobactam experience of use". In 25th Anniversary EAHP Congress, Hospital Pharmacy 5.0 – the future of patient care, 23–28 March 2021. British Medical Journal Publishing Group, 2021. http://dx.doi.org/10.1136/ejhpharm-2021-eahpconf.81.

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Rohrer, Amber, Daniel Conde, Samuel Montalvo, Manuel Gomez, Jennica Juarez e Gabriel Ibarra-Mejia. "Changes in Lactate After the Completion of Repetitive Cycle Exercises with and without Compression Arm Sleeves". In 13th International Conference on Applied Human Factors and Ergonomics (AHFE 2022). AHFE International, 2022. http://dx.doi.org/10.54941/ahfe1002617.

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Occupational compression sleeves are commonly used to relieve pain in the upper and lower extremities. Anecdotal data agree on the benefits of using compression sleeves while performing physical work. The purpose of this study was to assess the effects of wearing compression sleeves on the upper limbs on blood lactate concentration while completing a physically demanding activity. This study included six college-age participants from the University of Texas at El Paso. Anthropometric measurements were taken before the beginning of the study. Afterward, each participant’s basal capillary blood lactate level was established by averaging lactate concentration from three consecutive days. Capillary blood samples were taken from the participant’s earlobe, and lactate concentration (mmol/L) was assessed using the Lactate Plus Lactate Analyzer (Nova Biomedical). After obtaining all the baseline measurements, each participant completed six simulated work sessions, one with sleeves and another without sleeves, at an intensity of 25 Watts, 50 Watts, and 75 Watts a cadence of 60 RPM, and 10 minutes of duration. All participants rested for at least 72 hours between sessions to prevent muscular fatigue effects of lactate concentrations. The use of compression sleeves showed an average reduction of lactate concentration of 0.2 mmol/L. This study shows the potential benefits of wearing compression sleeves while performing activities involving the upper limbs by helping prevent lactate accumulation, a common indicator of muscular effort.
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Miesse, Peyton, e Gymama Slaughter. "Flexible Electrochemical Lactate Biosensor". In 2020 IEEE 15th International Conference on Nano/Micro Engineered and Molecular System (NEMS). IEEE, 2020. http://dx.doi.org/10.1109/nems50311.2020.9265579.

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Tong Jijun, Hu Jie, Huang Zhongchao, Pan Min e Chen Yuquan. "A Novel Lactate Biosensor". In 2005 IEEE Engineering in Medicine and Biology 27th Annual Conference. IEEE, 2005. http://dx.doi.org/10.1109/iembs.2005.1616391.

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Ramadan, L., J. Kaidbey e J. Bakker. "Lactate Levels Require Context". In American Thoracic Society 2022 International Conference, May 13-18, 2022 - San Francisco, CA. American Thoracic Society, 2022. http://dx.doi.org/10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a2909.

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Relatórios de organizações sobre o assunto "Lactame"

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Cang, Huai Qin, XiangHua Quan, XiangHua Chu, Yu Liang, Xue Yang e Jing Li. Carbapenems versus β-lactam and β-lactamase inhibitors for treatment of Nosocomial Pneumonia: a systematic review and meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, abril de 2023. http://dx.doi.org/10.37766/inplasy2023.4.0113.

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Chiu, Chia-Yu, e Amara Sarwal. Impact of area under the curve-based vancomycin dosing combination with anti-pseudomonal beta-lactam antibiotics: a systematic review and meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, dezembro de 2022. http://dx.doi.org/10.37766/inplasy2022.12.0025.

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Review question / Objective: Did AUC-based vancomycin dosing reduce acute kidney injury than trough-based dosing when combined with anti-pseudomonal beta-lactam antibiotic? Condition being studied: Patients received Vancomycin combined with anti-pseudomonal beta-lactam antibiotics and monitor with either trough-base dosing or AUC-based dosing vancomycin. Information sources: All study types except case reports, case series, and conference abstracts were considered. PubMed, Embase, Cochrane Library, and ClinicalTrials.gov were searched from inception to November2022.
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Mosher, Jennifer J., Meghan M. Drake, Susan L. Carroll, Zamin K. Yang, Christopher W. Schadt, Stephen D. Brown, Mircea Podar et al. Microbial Community Dynamics of Lactate Enriched Hanford Groundwaters. Office of Scientific and Technical Information (OSTI), maio de 2010. http://dx.doi.org/10.2172/986244.

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Meyer, Birte, e David Stahl. Syntrophic Degradation of Lactate in Methanogenic Co-cultures. Office of Scientific and Technical Information (OSTI), maio de 2010. http://dx.doi.org/10.2172/986317.

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Ma, Lianjia. Multichannel Simultaneous Determination of Activities of Lactate Dehydrogenase. Office of Scientific and Technical Information (OSTI), setembro de 2000. http://dx.doi.org/10.2172/764689.

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Piper, Robert C. Parasite Lactate Dehydrogenase for Diagnosis of Plasmodium Falciparum. Phase II. Fort Belvoir, VA: Defense Technical Information Center, abril de 1997. http://dx.doi.org/10.21236/adb230017.

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Kim, Yuan, Edward M. Steadham, Steven M. Lonergan e Elisabeth J. Huff-Lonergan. Antioxidant Capacity of Calcium Lactate on m-Calpain Activity In Vitro. Ames (Iowa): Iowa State University, janeiro de 2009. http://dx.doi.org/10.31274/ans_air-180814-1237.

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Reeves, John T. Beta-Adrenergic Blockade and Lactate Metabolism during Exercise at High Altitude. Fort Belvoir, VA: Defense Technical Information Center, janeiro de 1993. http://dx.doi.org/10.21236/ada263544.

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Burgers, E. E. A., R. M. A. Goselink e A. T. M. van Knegsel. Lactatie op maat : verlengen van de lactatie van melkvee: effecten op melkproductie, gezondheid en vruchtbaarheid van de koe en het economisch resultaat. Wageningen: Wageningen Livestock Research, 2022. http://dx.doi.org/10.18174/569099.

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Li, Yuan, Benjamin Metcalf, Sopio Chochua, Zhongya Li, Robert Gertz, Hollis Walker, Paulina Hawkins, Theresa Tran, Lesley McGee e Bernard W. Beall. Validation of β-lactam minimum inhibitory concentration predictions for pneumococcal isolates with newly encountered penicillin binding protein (PBP) sequences [Supporting data]. Centers for Disease Control and Prevention (U.S.), novembro de 2017. http://dx.doi.org/10.15620/cdc/147467.

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The datafiles, R scripts, MIC tables, and other files were used to evaluate the prediction performance of a penicillin-binding protein (PBP) typing system and two methods (Random Forest (RF) and Mode MIC (MM) previously developed by this research team. This data and these files support the finding of the paper "Validation of β-lactam minimum inhibitory concentration predictions for pneumococcal isolates with newly encountered penicillin binding protein (PBP) sequences" at https://doi.org/10.1186%2Fs12864-017-4017-7 or at https://stacks.cdc.gov/view/cdc/47684.
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