Bibliografias temáticas / Lungs Differentiation

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Literatura científica selecionada sobre o tema "Lungs Differentiation"

Autor: Grafiati
Publicado: 4 de junho de 2021
Última modificação: 29 de janeiro de 2023

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Artigos de revistas sobre o assunto "Lungs Differentiation"

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Ito, T., N. Udaka, T. Yazawa, K. Okudela, H. Hayashi, T. Sudo, F. Guillemot, R. Kageyama, and H. Kitamura. "Basic helix-loop-helix transcription factors regulate the neuroendocrine differentiation of fetal mouse pulmonary epithelium." Development 127, no. 18 (September 15, 2000): 3913–21. http://dx.doi.org/10.1242/dev.127.18.3913.

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To clarify the mechanisms that regulate neuroendocrine differentiation of fetal lung epithelia, we have studied the expression of the mammalian homologs of achaete-scute complex (Mash1) (Ascl1 - Mouse Genome Informatics); hairy and enhancer of split1 (Hes1); and the expression of Notch/Notch-ligand system in the fetal and adult mouse lungs, and in the lungs of Mash1- or Hes1-deficient mice. Immunohistochemical studies revealed that Mash1-positive cells seemed to belong to pulmonary neuroendocrine cells (PNEC) and their precursors. In mice deficient for Mash1, no PNEC were detected. Hes1-positi
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Chytil, F. "The lungs and vitamin A." American Journal of Physiology-Lung Cellular and Molecular Physiology 262, no. 5 (May 1, 1992): L517—L527. http://dx.doi.org/10.1152/ajplung.1992.262.5.l517.

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Evidence is reviewed supporting the view that vitamin A (retinol) and its metabolite, retinoic acid, called natural retinoids, are major factors involved in differentiation and in maturation of the lungs. This conclusion is based on morphological observation that lack of this dietary micronutrient causes keratinizing squamous metaplasia of the bronchopulmonary tree that can be reversed by refeeding the animal with retinol. In addition to these observations suggesting an indirect participation of retinol and/or retinoic acid in the differentiation of this organ, more direct evidence is presente
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Besnard, V., S. E. Wert, K. H. Kaestner, and J. A. Whitsett. "Stage-specific regulation of respiratory epithelial cell differentiation by Foxa1." American Journal of Physiology-Lung Cellular and Molecular Physiology 289, no. 5 (November 2005): L750—L759. http://dx.doi.org/10.1152/ajplung.00151.2005.

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Foxa1 is a member of the winged helix family of transcription factors that is expressed in epithelial cells of the conducting airways and in alveolar type II cells of the lung. To determine the role of Foxa1 during lung morphogenesis, histology and gene expression were assessed in lungs from Foxa1−/− gene-targeted mice from embryonic day (E) 16.5 to postnatal day (PN) 13. Deletion of Foxa1 perturbed maturation of the respiratory epithelium at precise times during lung morphogenesis. While dilatation of peripheral lung saccules was delayed in Foxa1−/− mice at E16.5, sacculation was unperturbed
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BRODY, J. "Alveolar cell differentiation markers in human lungs." Journal of Molecular and Cellular Cardiology 21 (February 1989): 161–64. http://dx.doi.org/10.1016/0022-2828(89)90852-3.

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Meierovics, Anda I., and Siobhán C. Cowley. "MAIT cells promote inflammatory monocyte differentiation into dendritic cells during pulmonary intracellular infection." Journal of Experimental Medicine 213, no. 12 (October 31, 2016): 2793–809. http://dx.doi.org/10.1084/jem.20160637.

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Mucosa-associated invariant T (MAIT) cells are a unique innate T cell subset that is necessary for rapid recruitment of activated CD4+ T cells to the lungs after pulmonary F. tularensis LVS infection. Here, we investigated the mechanisms behind this effect. We provide evidence to show that MAIT cells promote early differentiation of CCR2-dependent monocytes into monocyte-derived DCs (Mo-DCs) in the lungs after F. tularensis LVS pulmonary infection. Adoptive transfer of Mo-DCs to MAIT cell–deficient mice (MR1−/− mice) rescued their defect in the recruitment of activated CD4+ T cells to the lung
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Li, Changgong, Susan M. Smith, Neil Peinado, Feng Gao, Wei Li, Matt K. Lee, Beiyun Zhou, et al. "WNT5a-ROR Signaling Is Essential for Alveologenesis." Cells 9, no. 2 (February 7, 2020): 384. http://dx.doi.org/10.3390/cells9020384.

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WNT5a is a mainly “non-canonical” WNT ligand whose dysregulation is observed in lung diseases such as idiopathic pulmonary fibrosis (IPF), chronic obstructive pulmonary disease (COPD) and asthma. Germline deletion of Wnt5a disrupts embryonic lung development. However, the temporal-specific function of WNT5a remains unknown. In this study, we generated a conditional loss-of-function mouse model (Wnt5aCAG) and examined the specific role of Wnt5a during the saccular and alveolar phases of lung development. The lack of Wnt5a in the saccular phase blocked distal airway expansion and attenuated diff
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Raslan, Ahmed A., Youn Jeong Oh, Yong Ri Jin, and Jeong Kyo Yoon. "R-Spondin2, a Positive Canonical WNT Signaling Regulator, Controls the Expansion and Differentiation of Distal Lung Epithelial Stem/Progenitor Cells in Mice." International Journal of Molecular Sciences 23, no. 6 (March 13, 2022): 3089. http://dx.doi.org/10.3390/ijms23063089.

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The lungs have a remarkable ability to regenerate damaged tissues caused by acute injury. Many lung diseases, especially chronic lung diseases, are associated with a reduced or disrupted regeneration potential of the lungs. Therefore, understanding the underlying mechanisms of the regenerative capacity of the lungs offers the potential to identify novel therapeutic targets for these diseases. R-spondin2, a co-activator of WNT/β-catenin signaling, plays an important role in embryonic murine lung development. However, the role of Rspo2 in adult lung homeostasis and regeneration remains unknown.
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Lai, Jen-Feng, Lucas J. Thompson, and Steven F. Ziegler. "TSLP drives acute TH2-cell differentiation in lungs." Journal of Allergy and Clinical Immunology 146, no. 6 (December 2020): 1406–18. http://dx.doi.org/10.1016/j.jaci.2020.03.032.

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Alabed, Mashael, Asma Sultana Shaik, Narjes Saheb Sharif-Askari, Fatemeh Saheb Sharif-Askari, Shirin Hafezi, Bushra Mdkhana, Elaref Ratemi, Saleh Al-Muhsen, Qutayba Hamid, and Rabih Halwani. "Enhanced Infiltration of Central Memory T Cells to the Lung Tissue during Allergic Lung Inflammation." International Archives of Allergy and Immunology 183, no. 2 (October 20, 2021): 127–41. http://dx.doi.org/10.1159/000518835.

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Memory T cells play a central role in regulating inflammatory responses during asthma. However, tissue distribution of effector memory (T<sub>EM</sub>) and central memory (T<sub>CM</sub>) T-cell subtypes, their differentiation, and their contribution to the persistence of lung tissue inflammation during asthma are not well understood. Interestingly, an increase in survival and persistence of memory T cells was reported in asthmatic lungs, which may suggest a shift toward the more persistent T<sub>CM</sub> phenotype. In this report, we investigated the differ
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Bedoya, Felipe, Guang-Shing Cheng, Abigail Leibow, Nardine Zakhary, Katherine Weissler, Victoria Garcia, Elizabeth Kropf, et al. "Viral antigen induces differentiation of Foxp3+ natural regulatory T cells in influenza virus-infected mice (P1043)." Journal of Immunology 190, no. 1_Supplement (May 1, 2013): 139.11. http://dx.doi.org/10.4049/jimmunol.190.supp.139.11.

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Abstract We have examined the formation, participation and functional specialization of virus-reactive Foxp3+ regulatory T cells (Tregs) in a mouse model of influenza virus infection. “Natural” Tregs generated intra-thymically based on interactions with a self-peptide proliferated in response to a homologous viral antigen in the lungs, and to a lesser extent in the lung-draining mediastinal LN (medLN), of virus-infected mice. By contrast, conventional CD4+ T cells with identical TCR specificity underwent little or no conversion to become “adaptive” Tregs. The virus-reactive Tregs in the medLN
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Teses / dissertações sobre o assunto "Lungs Differentiation"

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Stogsdill, Jeffrey Alan. "Characterization of Altered Epithelial Cell Turnover and Differentiation in Embryonic Murine Lungs That Over-Express Receptors for Advanced Glycation End-Products (RAGE)." BYU ScholarsArchive, 2012. https://scholarsarchive.byu.edu/etd/3217.

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Receptors for advanced glycation end-products (RAGE) are multi-ligand cell surface receptors highly expressed in the lung that modulate pulmonary inflammation during disease. However, the contributions of RAGE signaling are unknown during pulmonary organogenesis. In order to test the hypothesis that RAGE misexpression adversely affects lung morphogenesis, conditional transgenic mice were generated that over-express RAGE in alveolar type II cells of the lung. When RAGE is over-expressed throughout embryogenesis, severe lung hypoplasia ensues, culminating in perinatal lethality. Flow cytometry a
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Lal, Arpita. "Relationship among differentiation of self, relationship satisfaction, partner support, depression, monitoring/blunting style, adherence to treatment and quality of life in patients with chronic lung disease." Columbus, Ohio : Ohio State University, 2006. http://rave.ohiolink.edu/etdc/view?acc%5Fnum=osu1164037503.

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Ansari, Naser A. (Naser Awni). "Purification and Characterization of a Differentiation Factor From Rat Lung Conditioned Medium." Thesis, North Texas State University, 1988. https://digital.library.unt.edu/ark:/67531/metadc798062/.

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A Differentiation Factor (DF) was purified from rat lung conditioned medium by a four-steps procedure. The DF has a molecular weight of 27000, and an isoelectric point of 4.70. Although DF is stable up to 60°C, it is sensitive to digestion by trypsin, chymotrypsin and subtilisin. DF forms granulocyte colonies in soft agar. Studies using anti-NRK CSF antibody demonstrated that DF is distinct from GM-CSF.
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Ansari, Naser A. (Naser Awni). "Mechanism of myeloid differentiation induced by a differentiation factor isolated from rat lung conditioned medium." Thesis, University of North Texas, 1991. https://digital.library.unt.edu/ark:/67531/metadc798429/.

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Berg, Tove. "C/EBP transcription factors in lung cellular differentiation and development /." Stockholm, 2005. http://diss.kib.ki.se/2005/91-7140-586-0/.

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Tompkins, David H. "Sox2 is a Master Regulator of Differentiation in Respiratory Epithelium." University of Cincinnati / OhioLINK, 2011. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1307985600.

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Alaqel, Abdullah. "The directed differentiation of human embryonic stem cells to lung cell lineages." Thesis, University of Bath, 2017. https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.760955.

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Human embryonic stem cells (hESCs) show significant therapeutic potential in treating degenerative disorders. This is in part because of their ability to produce a limitless supply of starting cells and their potential to differentiate into more than 200 different cell types. The aim of the current research was to generate a robust stage wise protocol for the differentiation of hESCs to respiratory epithelial cells. The epithelial cells could then be used either for transplantation studies or, as an in vitro model for drug toxicity testing. In order to achieve this goal, we must identify the k
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METZGER, DAVID EDWARD. "THE ROLE OF THE ETS TRANSCRIPTION FACTOR Elf5 IN LUNG DEVELOPMENT." University of Cincinnati / OhioLINK, 2007. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1197664589.

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Senden, Nicole Hubertina Maria. "NSP-reticulons characterization and use for the detection of neuroendocrine differentiation in lung cancer /." Maastricht : Maastricht : Universitaire Pers Maastricht ; University Library, Maastricht University [Host], 1995. http://arno.unimaas.nl/show.cgi?fid=8353.

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Soh, Boon Seng. "Optimization of Human Embryonic Stem Cells Culture and their Differentiation towards the Lung Lineage." Thesis, Imperial College London, 2010. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.516176.

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Livros sobre o assunto "Lungs Differentiation"

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1949-, Bernal Samuel D., Hesketh Paul J. 1952-, and International Conference on Lung Cancer (1990), eds. Lung cancer differentiation: Implications for diagnosis and treatment. New York: Marcel Dekker, Inc., 1992.

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Ito, Takaaki. Differentiation and proliferation of pulmonary neuroendocrine cells. Jena, Germany: Urban & Fischer, 1999.

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International IASLC Workshop on Lung Tumor and Differentiation Antigens (3rd 1993 Zurich, Switzerland). Third International IASLC Workshop on Lung Tumor and Differentiation Antigens: University Hospital, Zurich, Switzerland, September 8-11, 1993. [New York]: Published for the UICC by Wiley-Liss, 1994.

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1943-, McDonald John A., ed. Lung growth and development. New York: M. Dekker, 1997.

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5

Douglas, Kenneth. Bioprinting. Oxford University Press, 2021. http://dx.doi.org/10.1093/oso/9780190943547.001.0001.

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Abstract: This book describes how bioprinting emerged from 3D printing and details the accomplishments and challenges in bioprinting tissues of cartilage, skin, bone, muscle, neuromuscular junctions, liver, heart, lung, and kidney. It explains how scientists are attempting to provide these bioprinted tissues with a blood supply and the ability to carry nerve signals so that the tissues might be used for transplantation into persons with diseased or damaged organs. The book presents all the common terms in the bioprinting field and clarifies their meaning using plain language. Readers will lear
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Capítulos de livros sobre o assunto "Lungs Differentiation"

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Marin, L. "Lung Embryogenesis and Differentiation." In Physiology of the Fetal and Neonatal Lung, 1–15. Dordrecht: Springer Netherlands, 1987. http://dx.doi.org/10.1007/978-94-009-4155-7_1.

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Smith, B. T., M. Post, and J. Floros. "Differentiation of the Pulmonary Epithelium." In Physiology of the Fetal and Neonatal Lung, 17–24. Dordrecht: Springer Netherlands, 1987. http://dx.doi.org/10.1007/978-94-009-4155-7_2.

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Gaillard, Dominique, and Edith Puchelle. "Differentiation and Maturation of Airway Epithelial Cells: Role of Extracellular Matrix and Growth Factors." In Lung Development, 46–76. New York, NY: Springer New York, 1999. http://dx.doi.org/10.1007/978-1-4614-7537-8_3.

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Shimosato, Yukio, Setsuo Hirohashi, Takashi Nakajima, and Masayuki Noguchi. "Immunohistochemistry of Lung Cancer: Cell differentiation and Growth Properties." In Basic and Clinical Concepts of Lung Cancer, 71–87. Boston, MA: Springer US, 1989. http://dx.doi.org/10.1007/978-1-4613-1593-3_5.

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Snoeck, Hans-Willem. "Directed Differentiation of Human Pluripotent Stem Cells into Lung and Airway Epithelial Cells." In Stem Cells in the Lung, 265–85. Cham: Springer International Publishing, 2015. http://dx.doi.org/10.1007/978-3-319-21082-7_16.

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Alizadeh, Javad, Shahla Shojaei, Adel Sepanjnia, Mohammad Hashemi, Eftekhar Eftekharpour, and Saeid Ghavami. "Simultaneous Detection of Autophagy and Epithelial to Mesenchymal Transition in the Non-small Cell Lung Cancer Cells." In Autophagy in Differentiation and Tissue Maintenance, 87–103. New York, NY: Springer New York, 2017. http://dx.doi.org/10.1007/7651_2017_84.

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Zheng, Dahai, and Jianzhu Chen. "Culture and Differentiation of Lung Bronchiolar Epithelial Cells In Vitro." In Methods in Molecular Biology, 33–40. New York, NY: Springer New York, 2018. http://dx.doi.org/10.1007/978-1-4939-8600-2_4.

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Meleady, Paula, Finbar O’ Sullivan, Shirley McBride, and Martin Clynes. "Isolation, Cultivation and Differentiation of Lung Type II Epithelial Cells." In Animal Cell Culture Techniques, 357–70. Berlin, Heidelberg: Springer Berlin Heidelberg, 1998. http://dx.doi.org/10.1007/978-3-642-80412-0_19.

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Ray Banerjee, Ena. "Tissue Differentiation of ESC into Lung Cells and Functional Validation." In Perspectives in Regenerative Medicine, 39–65. New Delhi: Springer India, 2014. http://dx.doi.org/10.1007/978-81-322-2053-4_4.

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Cintrón, Rosa Vélez, Andrés J. Martínez, Jo Ann Jusino, María Conte-Miller, and Adalberto Mendoza. "Automated TTF-1 Immunohistochemistry Assay for the Differentiation of Lung Adenocarcinoma Versus Lung Squamous Cell Carcinoma." In Methods in Molecular Biology, 1–12. New York, NY: Springer US, 2021. http://dx.doi.org/10.1007/978-1-0716-1278-1_1.

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Trabalhos de conferências sobre o assunto "Lungs Differentiation"

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Pandit, Kusum, Jadranka Milosevic, Panayiotis Benos, Claudia Coronello, Ahmi Ben-Yehudah, James Hagood, Namasivayam Ambalavanan, and Naftali Kaminski. "Global Microrna Profiles Of Idiopathic Pulmonary Fibrosis Lungs Indicate Reversal Of Lung Differentiation." In American Thoracic Society 2011 International Conference, May 13-18, 2011 • Denver Colorado. American Thoracic Society, 2011. http://dx.doi.org/10.1164/ajrccm-conference.2011.183.1_meetingabstracts.a5528.

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Danopoulos, S., S. Bhattacharya, C. Cherry, G. Deutsch, T. Mariani, and D. Al Alam. "Transcriptional characterization suggests accelerated epithelial differentiation in Trisomy 21 Lungs." In ERS International Congress 2022 abstracts. European Respiratory Society, 2022. http://dx.doi.org/10.1183/13993003.congress-2022.4105.

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Danopoulos, S., S. Bhattacharya, C. Cherry, G. Deutsch, T. J. Mariani, and D. Al Alam. "Transcriptional Characterization Suggests Accelerated Epithelial Differentiation in Trisomy 21 Lungs." In American Thoracic Society 2022 International Conference, May 13-18, 2022 - San Francisco, CA. American Thoracic Society, 2022. http://dx.doi.org/10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a5294.

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Luo, Y., H. Chen, J. Chiu, and W. Shi. "Epithelial Differentiation and the Proximal-Distal Axis Are Disrupted in MesenchymeBmpr1a Knockout Fetal Lungs." In American Thoracic Society 2022 International Conference, May 13-18, 2022 - San Francisco, CA. American Thoracic Society, 2022. http://dx.doi.org/10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a3261.

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Hecker, L., T. Jones, JC Horowitz, VN Lama, and VJ Thannickal. "Multipotent Differentiation of Mesenchymal Stem/Progenitor Cells Isolated from Lungs of Patients with Idiopathic Pulmonary Fibrosis." In American Thoracic Society 2009 International Conference, May 15-20, 2009 • San Diego, California. American Thoracic Society, 2009. http://dx.doi.org/10.1164/ajrccm-conference.2009.179.1_meetingabstracts.a2004.

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Karnati, Srikanth, and Eveline Baumgart-Vogt. "Alteration Of ROS Metabolism And Cell Type-Specific Differentiation Markers In The Lungs Of Pex11ß (-/-) Mice, A Mouse Model Deficient In Peroxisome Proliferation." In American Thoracic Society 2012 International Conference, May 18-23, 2012 • San Francisco, California. American Thoracic Society, 2012. http://dx.doi.org/10.1164/ajrccm-conference.2012.185.1_meetingabstracts.a4950.

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Ritzmann, F., R. Sprott, F. Langer, C. Herr, C. Lehr, T. Tschernig, R. Bals, and C. Beisswenger. "Toll-like receptor signaling regulates the differentiation of 3D bronchospheres." In ERS Lung Science Conference 2020 abstracts. European Respiratory Society, 2020. http://dx.doi.org/10.1183/23120541.lsc-2020.92.

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Goossens, Janne, Toon Ieven, Ellen Dilissen, Anne-Charlotte Jonckheere, Jonathan Cremer, Lieven Dupont, and Dominique Bullens. "Human mast cell differentiation optimization to study MRGPRX2-induced activation in vitro." In ERS Lung Science Conference 2022 abstracts. European Respiratory Society, 2022. http://dx.doi.org/10.1183/23120541.lsc-2022.63.

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yao, yiwen, Felix Ritzmann, Alex Zimmer, Robert Bals, and Christoph Beisswenger. "Fibroblasts drive the differentiation of murine pneumocytes in air-liquid interface cultures." In ERS Lung Science Conference 2022 abstracts. European Respiratory Society, 2022. http://dx.doi.org/10.1183/23120541.lsc-2022.121.

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Zahavi, J., S. Zaltzman, E. Firsteter, and E. Avrahami. "SEMI-QUANTITATIVE RADIONUCLIDE PHLEBOGRAPHIC (RNP) ASSESSMENT OF DEEP VEIN THROMBOSIS (DVT) AND CHRONIC VENOUS INSUFFICIENCY (CVI)." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1642895.

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A semi-quantitative RNP using 99Technetium macroaggregated albumin for the evaluation and follow-up of DVT and CVI has been developed. Values were assigned to the deep veins of the calf, knee, tigh and pelvis based upon the localization and the characteristics of the images obtained: stasis, hot spots and collateral circulation. A maximum score of 18 reflected complete thrombosis of all 4 segments. 208 patients (mean age 53.7 years, range 18-92), 161 of whom had a proven risk factor for DVT were studied. 99Technetium was injected into the dorsal foot vein of 407 limbs with appropriate tourniqu
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Relatórios de organizações sobre o assunto "Lungs Differentiation"

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Dooner, Mark, Jason M. Aliotta, Jeffrey Pimental, Gerri J. Dooner, Mehrdad Abedi, Gerald Colvin, Qin Liu, Heinz-Ulli Weier, Mark S. Dooner, and Peter J. Quesenberry. Cell Cycle Related Differentiation of Bone Marrow Cells into Lung Cells. Office of Scientific and Technical Information (OSTI), December 2007. http://dx.doi.org/10.2172/936517.

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