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1

Jessani, Abbas, Mir Faeq Ali Quadri, Pulane Lefoka, et al. "Oral Health Status and Patterns of Dental Service Utilization of Adolescents in Lesotho, Southern Africa." Children 8, no. 2 (2021): 120. http://dx.doi.org/10.3390/children8020120.

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This study aimed to characterize the best predictors for unmet dental treatment needs and patterns of dental service utilization by adolescents in the Kingdom of Lesotho, Southern Africa. A self-reported 40-item oral health survey was administered, and clinical oral examinations were conducted in public schools in Maseru from August 10 to August 25, 2016. Associations between psychosocial factors with oral health status and dental service utilization were evaluated using simple, bivariate, and multivariate regressions. Five hundred and twenty-six survey responses and examinations were gathered
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2

Logie, Carmen H., Lisa V. Dias, Jesse Jenkinson, et al. "Exploring the Potential of Participatory Theatre to Reduce Stigma and Promote Health Equity for Lesbian, Gay, Bisexual, and Transgender (LGBT) People in Swaziland and Lesotho." Health Education & Behavior 46, no. 1 (2018): 146–56. http://dx.doi.org/10.1177/1090198118760682.

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Stigma and discrimination affecting lesbian, gay, bisexual, and transgender (LGBT) people compromise health and human rights and exacerbate the HIV epidemic. Scant research has explored effective LGBT stigma reduction strategies in low- and middle-income countries. We developed and pilot-tested a participatory theatre intervention (PTI) to reduce LGBT stigma in Swaziland and Lesotho, countries with the world’s highest HIV prevalence. We collected preliminary data from in-depth interviews with LGBT people in Lesotho and Swaziland to enhance understanding of LGBT stigma. Local LGBT and theatre g
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3

Mabaleha, Mohale B., Pieter C. Zietsman, Anke Wilhelm, and Susan L. Bonnet. "Ethnobotanical Survey of Medicinal Plants Used to Treat Mental Illnesses in the Berea, Leribe, and Maseru Districts of Lesotho." Natural Product Communications 14, no. 7 (2019): 1934578X1986421. http://dx.doi.org/10.1177/1934578x19864215.

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Mental illnesses (MIs) such as anxiety, epilepsy, major depression, schizophrenia, sleep disorder, and pain influence the quality of life severely. According to the World Health Organization Atlas for Mental Health (2014), the formal health sector in Lesotho has only 13.7 mental health workers per 100 000 of the population, which breaks down to 0.1 psychiatrist and other medical doctors, 0.3 psychologists, 4.7 nurses, and 5.2 social workers. Traditional health practitioners (THPs) have always played a significant role in the prevention and treatment of MIs, via utilization of Lesotho’s vast di
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4

Mugomeri, Eltony, Palesa Khama, Polo C. Seshea, et al. "The occurrence and quality of care of non-communicable diseases in people living with HIV in Maseru, Lesotho: a mixed-methods study." HIV & AIDS Review 3 (2017): 155–62. http://dx.doi.org/10.5114/hivar.2017.67788.

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5

Madiba, Sphiwe, and Mamorapeli Putsoane. "Testing Positive and Disclosing in Pregnancy: A Phenomenological Study of the Experiences of Adolescents and Young Women in Maseru, Lesotho." AIDS Research and Treatment 2020 (February 12, 2020): 1–8. http://dx.doi.org/10.1155/2020/6126210.

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The routine antenatal screening through the prevention of mother to child transmission of HIV (PMTCT) services results in pregnancy being often the point at which an HIV diagnosis is made. Disclosure to partners presents particular complexities during pregnancy. However, research on the pattern and experiences of disclosure in pregnancy is limited in Lesotho, despite the high prevalence of HIV among pregnant women. The aim of this study was to explore and describe the disclosure experiences of adolescent girls and young women (AGYW) after receiving a positive HIV test result during pregnancy.
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6

Moteetee, A., and B. E. Van Wyk. "The medical ethnobotany of Lesotho: a review." Bothalia 41, no. 1 (2011): 209–28. http://dx.doi.org/10.4102/abc.v41i1.52.

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Traditional healing in Lesotho is reviewed, focusing on four aspects: 1, cultural practices; 2, traditional health care practitioners; 3, dosage forms; 4, the materia medica. Cultural practices are strongly associated with the belief that intangible forces are responsible for human happiness and misery. A total of 303 plant species are used medicinally (including 25 alien species), representing eight pteridophyte and 75 angiosperm families, of which the most important are Asteraceae, Fabaceae, Hyacinthaceae, Apocynaceae, Scrophulariaceae, Lamiaceae and Poaceae. Dicoma anomala (used mainly for
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7

Furin, Jennifer, Mike Shutts, and Salmaan Keshavjee. "Aviation and the Delivery of Medical Care in Remote Regions: The Lesotho HIV Experience." Aviation, Space, and Environmental Medicine 79, no. 2 (2008): 136–38. http://dx.doi.org/10.3357/asem.2134.2008.

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8

Thabane, Motlatsi. "Public mental health care in colonial Lesotho: themes emerging from archival material, 1918–35." History of Psychiatry 32, no. 2 (2021): 146–61. http://dx.doi.org/10.1177/0957154x21989176.

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This paper identifies some of the themes that emerge from a study of official archival records from 1918 to 1934 on the subject of mental health in colonial Lesotho. They include: difficulties experienced by colonial medical doctors in diagnosing and treating mental illnesses, given the state of medical knowledge in the nineteenth and early twentieth centuries; impact of shortage of financial and other resources on the establishment and operation of medical services, especially mental health care; convergence of social order, financial and medical concerns as influences on colonial approaches
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9

Gill, Michelle M., Rhoderick Machekano, Anthony Isavwa, et al. "The Association Between HIV Status and Antenatal Care Attendance Among Pregnant Women in Rural Hospitals in Lesotho." JAIDS Journal of Acquired Immune Deficiency Syndromes 68, no. 3 (2015): e33-e38. http://dx.doi.org/10.1097/qai.0000000000000481.

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10

Macneal, Kenneth, Vincent Tukei, Emma Sacks, et al. "Use of Point-of-Care Nucleic Acid Tests Beyond Early Infant Diagnosis of HIV: A Retrospective Case Review in Lesotho." JAIDS Journal of Acquired Immune Deficiency Syndromes 84, no. 1 (2020): S78—S83. http://dx.doi.org/10.1097/qai.0000000000002381.

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11

Hollifield, Michael, Wayne Katon, and Neo Morojele. "Anxiety and Depression in an Outpatient Clinic in Lesotho, Africa." International Journal of Psychiatry in Medicine 24, no. 2 (1994): 179–88. http://dx.doi.org/10.2190/x3xa-lpjb-c3kw-amly.

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Objective: Past studies of psychiatric disorders in primary care in developing countries have utilized measures to determine conspicuous psychiatric morbidity (CPM) rather than diagnoses. Our goal was to determine the prevalence of DSM-III major depression (DEP), panic disorder (PD), and generalized anxiety disorder (GAD) in an outpatient clinic in Lesotho, Africa. Methods: As part of a larger community study, we utilized a translated version of the N.I.M.H. Diagnostic Interview Schedule to determine the prevalence of DEP, PD, and GAD in 126 randomly selected outpatients (response rate = 77%)
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12

Amstutz, Alain, Jennifer Anne Brown, Isaac Ringera, et al. "Engagement in Care, Viral Suppression, Drug Resistance, and Reasons for Nonengagement After Home-Based Same-Day Antiretroviral Therapy Initiation in Lesotho: A Two-Year Follow-up of the CASCADE Trial." Clinical Infectious Diseases 71, no. 10 (2019): 2608–14. http://dx.doi.org/10.1093/cid/ciz1126.

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Abstract Background The CASCADE trial showed that compared with usual care (UC), offering same-day (SD) antiretroviral therapy (ART) during home-based human immunodeficiency virus testing improved engagement in care and viral suppression 12 months after diagnosis. However, questions remain regarding long-term outcomes and the risk of propagating drug resistance. Methods After completion of the primary endpoint at 12 months, participants not in care in both arms were traced and encouraged to access care. At 24 months, the following outcomes were assessed in both arms: engagement in care, viral
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13

Low, Andrea, Chloe Teasdale, Kristin Brown, et al. "Human Immunodeficiency Virus Infection in Adolescents and Mode of Transmission in Southern Africa: A Multinational Analysis of Population-Based Survey Data." Clinical Infectious Diseases 73, no. 4 (2021): 594–604. http://dx.doi.org/10.1093/cid/ciab031.

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Abstract Background Adolescents aged 10–19 years living with human immunodeficiency virus (HIV) (ALHIV), both perinatally infected adolescents (APHIV) and behaviorally infected adolescents (ABHIV), are a growing population with distinct care needs. We characterized the epidemiology of HIV in adolescents included in Population-based HIV Impact Assessments (2015–2017) in Zimbabwe, Malawi, Zambia, Eswatini, and Lesotho. Methods Adolescents were tested for HIV using national rapid testing algorithms. Viral load (VL) suppression (VLS) was defined as VL <1000 copies/mL, and undetectable VL (U
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14

Taniguchi, Cullen M., Anuja Jhingran, Shane Richard Stecklein, et al. "A pilot course of intensive training in radiation biology and physics for oncologists in sub-Saharan Africa." Journal of Global Oncology 5, suppl (2019): 24. http://dx.doi.org/10.1200/jgo.2019.5.suppl.24.

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24 Background: Radiation therapy is an essential component of cancer care used for palliative and curative treatments access a wide spectrum of disease, but many low- and middle-income countries do not have equitable access to this technology or training in the radiation sciences. Towards this end, we launched a pilot program to teach the principles of radiation biology and radiation physics that are a basic component of training and credentialing of radiation oncologists in the United States. Methods: We designed a 5 days curriculum for radiation biology and radiation physics that were simila
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15

Murye, AF, and SM Mohale. "Health care waste management in the Maseru district of Lesotho." UNISWA Research Journal of Agriculture, Science and Technology 8, no. 2 (2006). http://dx.doi.org/10.4314/uniswa-rjast.v8i2.4752.

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16

Ntlale, Matsola E., and Sinegugu E. Duma. "The costs and benefits of nurse migration on families: A Lesotho experience." Curationis 34, no. 1 (2011). http://dx.doi.org/10.4102/curationis.v34i1.13.

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The present day migration of nurses from developing countries, to more developed countries,depletes these countries of this vital human resource, which is necessary to provide optimum quality nursing care to their populations. If nurse migration persists, the health systems of these countries face collapse.It is important that a nurse understands the costs and benefits of migration to their families, whom they leave behind. This is not only to curb the problems that may occur, but to help the migrant nurses to realise how migration affects their families, especially their children and spouses,
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17

Bryden, Benjamin, Mariel Bryden, Jonathan Steer-Massaro, and Sebaka Malope. "Family Medicine Training in Lesotho: A Strategy of Decentralized Training for Rural Physician Workforce Development." Frontiers in Medicine 7 (January 14, 2021). http://dx.doi.org/10.3389/fmed.2020.582130.

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Family medicine is a relatively new but rapidly expanding medical discipline in Sub-Saharan Africa. Specialization in family medicine is an effective means for building and retaining a highly skilled rural physician workforce in low- and middle-income countries. The Lesotho Boston Health Alliance Family Medicine Specialty Training Program is the first and only postgraduate family medicine program and the only accredited postgraduate training program in the Kingdom of Lesotho. Lesotho has unique challenges as a small mountainous enclave of South Africa with one of the lowest physician-to-patien
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18

Leyenaar, JoAnna K., Paul M. Novosad, Katheleen T. Ferrer, et al. "Early Clinical Outcomes in Children Enrolled in Human Immunodeficiency Virus Infection Care and Treatment in Lesotho." Pediatric Infectious Disease Journal, December 2009, 1. http://dx.doi.org/10.1097/inf.0b013e3181bf8ecb.

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19

Mataka, Anafi, Esther A. J. Tumbare, Tsietso Motsoane, et al. "Strategic site selection for placement of HIV early infant diagnosis point-of-care technology within a national diagnostic network in Lesotho." African Journal of Laboratory Medicine 10, no. 1 (2021). http://dx.doi.org/10.4102/ajlm.v10i1.1156.

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20

Ballif, Marie, Benedikt Christ, Nanina Anderegg, et al. "Tracing People Living With Human Immunodeficiency Virus Who Are Lost to Follow-up at Antiretroviral Therapy Programs in Southern Africa: A Sampling-Based Cohort Study in 6 Countries." Clinical Infectious Diseases, May 16, 2021. http://dx.doi.org/10.1093/cid/ciab428.

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Abstract Background Attrition threatens the success of antiretroviral therapy (ART). In this cohort study, we examined outcomes of people living with human immunodeficiency virus (PLHIV) who were lost to follow-up (LTFU) during 2014–2017 at ART programs in Southern Africa. Methods We confirmed LTFU (missed appointment for ≥60 or ≥90 days, according to local guidelines) by checking medical records and used a standardized protocol to trace a weighted random sample of PLHIV who were LTFU in 8 ART programs in Lesotho, Malawi, Mozambique, South Africa, Zambia, and Zimbabwe, 2017–2019. We ascertaine
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21

Mapesi, Herry, Ravi Gupta, Herieth Ismael Wilson, et al. "The coArtHA trial—identifying the most effective treatment strategies to control arterial hypertension in sub-Saharan Africa: study protocol for a randomized controlled trial." Trials 22, no. 1 (2021). http://dx.doi.org/10.1186/s13063-021-05023-z.

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Abstract Background Arterial hypertension is the most prevalent risk factor for cardiovascular disease in sub-Saharan Africa. Only a few and mostly small randomized trials have studied antihypertensive treatments in people of African descent living in sub-Saharan Africa. Methods In this open-label, three-arm, parallel randomized controlled trial conducted at two rural hospitals in Lesotho and Tanzania, we compare the efficacy and cost-effectiveness of three antihypertensive treatment strategies among participants aged ≥ 18 years. The study includes patients with untreated uncomplicated arteria
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22

Mugomeri, Eltony, Dedré Olivier, and Wilhelmiena M. J. Van den Heever. "Tracking the rate of initiation and retention on isoniazid preventive therapy in a high human immunodeficiency virus and tuberculosis burden setting of Lesotho." Southern African Journal of Infectious Diseases 34, no. 1 (2019). http://dx.doi.org/10.4102/sajid.v34i1.10.

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Background: Tuberculosis (TB) remains a public health problem, particularly in people living with human immunodeficiency virus (PLHIV). Yet, efforts to reduce TB incidence using isoniazid preventive therapy (IPT) have been curtailed by poor uptake of this intervention. This study reviewed the rate of IPT initiation in the sub-Saharan country of Lesotho, which has one of the highest TB incidences in the world.Methods: Time to IPT initiation in randomly sampled medical records of PLHIV was analysed using Cox’s proportional hazards regression. Differences in the periods of enrolment into Human im
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