Bibliografias temáticas / Methylone

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Literatura científica selecionada sobre o tema "Methylone"

Autor: Grafiati
Publicado: 4 de junho de 2021
Última modificação: 1 de fevereiro de 2022

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Artigos de revistas sobre o assunto "Methylone"

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Poyatos, Lourdes, Esther Papaseit, Eulalia Olesti, et al. "A Comparison of Acute Pharmacological Effects of Methylone and MDMA Administration in Humans and Oral Fluid Concentrations as Biomarkers of Exposure." Biology 10, no. 8 (2021): 788. http://dx.doi.org/10.3390/biology10080788.

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Considered the β-keto analogue of 3,4-methylenedioxymethamphetamine (MDMA, ecstasy), 3,4-Methylenedioxymethcathinone (methylone) is a synthetic cathinone. Over the years, methylone has been used as a substitute for conventional psychostimulants, such as MDMA. To date, little is known about the human pharmacology of methylone; the only available information has been provided by surveys or published intoxication reports. In the present observational–naturalistic study, we evaluate the acute subjective and physiological effects of methylone after oral self-administration in comparison to MDMA in
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Sadurní, L. Martínez, M. Grifell, L. Galindo, et al. "Methylone consumption characterized through samples handled by users." European Psychiatry 33, S1 (2016): S117. http://dx.doi.org/10.1016/j.eurpsy.2016.01.129.

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IntroductionIn recent years, the increasing use tendency of NPS has motivated both awareness and concern about their identification and potential harmfulness. Synthetic cathinones represent a significant proportion of the NPS available and methylone is one of the most frequently found in Europe.ObjectivesThe aim of the present study is to determine methylone presence and characteristics from the samples analyzed by Energy Control between the years 2009 and 2015 in Spain.MethodsFrom all 21,198 samples analyzed from august 2009 to august 2015, only those in which methylone was found are studied
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Monteagudo, E., M. de Dios, A. Trabsa, et al. "Is methylone a new public health threat in Spain?" European Psychiatry 41, S1 (2017): s871. http://dx.doi.org/10.1016/j.eurpsy.2017.01.1749.

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IntroductionDue to the continuous search for new, legal, less expensive, and more powerful highs by drug users, the synthesis of novel cathinone derivatives has become a fruitful industry, leading to a fast emergence of new alternative substances every year. Methylone (3,4-methylenedioxy-N-methylcathinone) is one of the substances that rapidly emerged as the main ingredient of “bath salts”, becoming readily accessible on the Internet. This fact has raised concerns about its potential harmfulness.ObjectivesThe aim of the present study is to analyze the presence of methylone in samples delivered
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Barrios, L., H. Grison-Hernando, D. Boels, R. Bouquie, C. Monteil-Ganiere, and R. Clement. "Death following ingestion of methylone." International Journal of Legal Medicine 130, no. 2 (2015): 381–85. http://dx.doi.org/10.1007/s00414-015-1212-4.

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Centazzo, Nicole, Michael R. Chojnacki, Joshua S. Elmore, et al. "Brain Concentrations of Methylone and Its Metabolites after Systemic Methylone Administration: Relationship to Pharmacodynamic Effects." Journal of Pharmacology and Experimental Therapeutics 377, no. 3 (2021): 398–406. http://dx.doi.org/10.1124/jpet.121.000531.

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Piao, Ying-Shan, Frank Scott Hall, Yuki Moriya, et al. "Methylone-induced hyperthermia and lethal toxicity." Behavioural Pharmacology 26, no. 4 (2015): 345–52. http://dx.doi.org/10.1097/fbp.0000000000000135.

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Pearson, J. M., T. L. Hargraves, L. S. Hair, et al. "Three Fatal Intoxications Due to Methylone." Journal of Analytical Toxicology 36, no. 6 (2012): 444–51. http://dx.doi.org/10.1093/jat/bks043.

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Kovács, Katalin, Anita Réka Tóth, and Éva Margit Kereszty. "A new designer drug: Methylone related death." Orvosi Hetilap 153, no. 7 (2012): 271–76. http://dx.doi.org/10.1556/oh.2012.29310.

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This report presents a fatal case related to the consumption of methylone, a relatively new cathinone type designer drug. A 16-year-old boy suddenly lost his consciousness in a party. Resuscitation had been continued for about 1.5 hours at the intensive care unit, but it was unsuccessful. His previous history included cardiac malformation detected at infancy and bronchial asthma had been diagnosed one year before his death. Signs of sudden cardiac death were observed during autopsy. Methylone intake was proved in blood and liver extract using gas chromatography/mass spectrometry; its concentra
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Sogawa, Chiharu, Norio Sogawa, Kazumi Ohyama, et al. "Methylone and Monoamine Transporters: Correlation with Toxicity." Current Neuropharmacology 9, no. 1 (2011): 58–62. http://dx.doi.org/10.2174/157015911795017425.

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Carbone, Peter, David L. Carbone, Shaun Carstairs, and Scott A. Luzi. "Sudden Cardiac Death Associated With Methylone Use." American Journal of Clinical Pathology 138, suppl 2 (2012): A320. http://dx.doi.org/10.1093/ajcp/138.suppl2.50.

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Teses / dissertações sobre o assunto "Methylone"

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Daniel, Jollee Jaye. "Adolescent Methylone Exposure and its Effects on Behavioural Development in Adulthood." Thesis, University of Canterbury. Psychology, 2011. http://hdl.handle.net/10092/5460.

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Originally developed as an anti-depressant and later available as a ‘party-pill’ in New Zealand, methylone is currently classed as an illegal drug. This is due to findings of its similarity in chemical structure to that of Ecstasy (MDMA). Methylone is a relatively new drug into which little research has been conducted. Consequently, no known study has investigated the long-term effects on behavioural development arising from exposure during adolescence. The present thesis therefore aimed to identify long-term effects of chronic adolescent exposure to methylone on adult anxiety-like behaviours.
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2

Allen, Serena. "The Combined Neuropharmacology and Toxicology of Major 'Bath Salts' Constituents MDPV, Mephedrone, and Methylone." Digital Commons @ East Tennessee State University, 2018. https://dc.etsu.edu/etd/3431.

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The synthetic cathinones, 3,4- methylenedioxypyrovalerone (MDPV), 4-methylmethcathinone (mephedrone), and 3,4- methylenedioxymethcathinone (methylone), gained worldwide notoriety as the psychoactive components of ‘bath salts;’ a marketing term used to circumvent federal drug laws and permit their legal sale. Previous studies have shown that these drugs share pharmacological characteristics with cocaine and the amphetamines, however, descriptions of their neurotoxic properties are limited. Moreover, while forensic analysis has revealed that the most frequently abused bath salts ‘brands’ contain
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Troglin, Courtney G., J. Brooke Bouldin, Shannon Schreiner, Emily Perez, Stacy D. Ph D. Brown, and Brooks B. Ph D. Pond. "Pharmacokinetics of individual versus combined exposure to "bath salts" compounds MDPV, Mephedrone, and Methylone." Digital Commons @ East Tennessee State University, 2019. https://dc.etsu.edu/asrf/2019/schedule/182.

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Earlier this decade, “bath salts” were popularized as legal alternatives to the pyschostimulants cocaine and the amphetamines. These products contained synthetic cathinones including 3,4-methylenedioxypyrovalerone (MDPV), 4-methylmethcathinone (mephedrone), and 3,4-methylenedioxymethcathinone (methylone). Studies indicate that the cathinones have similar pharmacology to controlled psychostimulants, increasing levels of dopamine (DA) in the synaptic cleft. Most preclinical investigations have only assessed the effect of these synthetic cathinones independently; however, case reports and DEA s
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Tran, Lily H., Serena A. Allen, Hannah V. Oakes, Russell W. Brown, and Brooks B. Pond. "Dopaminergic Effects of major Bath Salt Constituents 3, 4-methylenedioxypyrovalerone (MDPV), Mephedrone, and Methylone are Enhanced Following Co-exposure." Digital Commons @ East Tennessee State University, 2019. https://dc.etsu.edu/asrf/2019/schedule/139.

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An unprecedented rise in the availability of new synthetic drugs of abuse has been observed in the recent years. One of the most noted cases is that of a popularized designer drug mixture known as ‘bath salts’. Commonly obtained from various shops and on the internet, “bath salts” often contain the synthetic cathinones 3,4 methylenedioxypyrovalerone (MDPV), mephedrone, and methylone in diverse combinations. Individually, the synthetic cathinones are known to have similar pharmacology to controlled psychostimulants such as cocaine and the amphetamines, increasing the levels of dopamine (DA) in
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Pachhain, Sudhan. "Analysis of gene expression associated with drug-induced hyperthermia in rat." Bowling Green State University / OhioLINK, 2019. http://rave.ohiolink.edu/etdc/view?acc_num=bgsu1562330027757666.

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Schreiner, Shannon CA, J. Brooke Bouldin, Emily Perez, Stacy D. Brown, and Brooks B. Pond. "PHARMACOKINETICS OF SYNTHETIC CATHINONES FOUND IN "BATH SALTS" IN MOUSE BRAIN AND PLASMA USING LIQUID CHROMATOGRAPHY - MASS SPECTROMETRY." Digital Commons @ East Tennessee State University, 2018. https://dc.etsu.edu/asrf/2018/schedule/196.

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“Bath salts” and “plant food”, which were legally marketed synthetic cathinones, have a high potential for abuse. Several recent studies indicate that 3,4-methylenedioxypyrovalerone (MDPV) and 3,4-methylenedioxymethcathinone (methylone), two common drugs of this type, have similar pharmacology to controlled psychostimulants such as cocaine, methamphetamine, and methylphenidate. MDPV acts as a norepinephrine (NE) and dopamine (DA) reuptake inhibitor via blockade of their transporters (DAT and NET), whereas methylone is a substrate for the NE, DA, and serotonin (5-HT) transporters, increasing t
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López, Arnau Raúl. "Nuevas drogas psicoestimulantes. Estudio farmacológico y neurotoxicológico de la metilona." Doctoral thesis, Universitat de Barcelona, 2014. http://hdl.handle.net/10803/284625.

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La metilona (3,4-metilendioximetcatinona), también conocida como M1, MDMC, bk-MDMA o “Ease” es un psicoestimulante y entactógeno de la familia de las catinonas, también incluida dentro del grupo de las fenetilaminas o de las β-ceto anfetaminas. Cabe destacar que la metilona posee una gran similitud estructural con la MDMA o “éxtasis” (Figura 20), de la cual sólo difiere por la presencia de un grupo cetona en la posición β del anillo de fenetilamina. La mayoría de estas catinonas poseen una similitud estructural con otros derivados anfetamínicos, como la MDMA o la metanfetamina por lo que sus e
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DEMBELE, YENIMEGUE-ALBERT. "Synthese asymetrique d'alpha-methylene gamma-butyrolactames." Nantes, 1991. http://www.theses.fr/1991NANT2045.

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L'utilisation d'(alpha-bromomethyl) acrylates d'alkyles et d'imines en presence de zinc dans des conditions appropriees demeure la meilleure voie d'acces aux alpha-methylene gamma-butyrolactames. Au cours de cette etude, nous avons realise la premiere synthese totalement selective d'alpha-methylene gamma-butyrolactames secondaires chiraux, avec de bons rendements chimiques par transfert de chiralite lors du couplage d'organozinciques derives d'alpha-bromomethyl) acrylates, et d'une imine portant une copule chirale issue d'un alpha-aminoester ou d'un beta-aminoalcool
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GRUIEC, ANNE. "Halogenation, arylation, alkylation et lactonisation des 3-hydroxy 2-methylene propanoates de methyle et de leurs nitriles en presence de sels metalliques deposes sur un support solide." Rennes 1, 1991. http://www.theses.fr/1991REN10055.

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On montre, en utilisant comme substrat les 3-hydroxy 2-methylene propanoates de methyle et les nitriles correspondants que la reactivite des halogenures de cu#+#2, co#+#2, fe#+#3, zn#+#2 et mn#+#2, depose sur un support solide inorganique est plus grande que la reactivite des sels purs. Une etude electrochimique du bromure cuivrique depose sur silica gel montre que le sel est dans un etat hautement divise. Le melange se comporte comme une source d'ions bromure vis-a-vis du substrat organique. Ces halogenures metalliques deposes sur silica gel ont permis de realiser avec les esters et nitriles
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Provencal, Nadine. "The methylome of early adversity and aggression." Thesis, McGill University, 2013. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=114317.

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Acts of violence account for 1.43 million deaths worldwide annually and individual acts of aggression account for the majority of these lives lost. Longitudinal studies on the development of physical aggression have found that while children start using physical aggression very early in life, the majority of them learn to use alternative behaviors during childhood and adolescence. The challenge is that a minority of children (3-7%) maintain chronic levels of physical aggression. While we know that genetic factors and early social experiences are involved in the development of aggression, the m
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Livros sobre o assunto "Methylone"

1

Illing, H. P. A. Dichloromethane (methylene chloride). HMSO, 1985.

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2

Organisation, International Labour, United Nations Environment Programme, and World Health Organization, eds. Methylene chloride health and safety guide. World Health Organization, 1987.

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3

Leeming, Peter. 2-methylene-1,3-dioxolanes: Mechanistic and synthetic studies. University of Salford, 1994.

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4

Nefedov, O. M. Khimii͡a︡ karbenov. Khimii͡a︡, 1990.

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5

Jurga, Stefan, and Jan Barciszewski, eds. The DNA, RNA, and Histone Methylomes. Springer International Publishing, 2019. http://dx.doi.org/10.1007/978-3-030-14792-1.

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V, Kazimirchik I., Lukin K. A, and Nefedov O. M, eds. T͡S︡ikloprisoedinenie dikhlorkarbena k olefinam. "Nauka", 1985.

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7

Webb, Michelle. Structure and function of the EcoR1241 DNA methylase. University of Portsmouth, School of Biological Sciences, 1995.

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Mernagh, Darren Richard. Studies on EcoR124I methylase and its interaction with DNA. University of Portsmouth, School of Biological Sciences, 1995.

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9

U, Schubert, ed. Advances in metal carbene chemistry. Kluwer Academic Publishers, 1989.

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Metal carbenes in organic synthesis. Wiley-VCH, 1999.

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Capítulos de livros sobre o assunto "Methylone"

1

Kiyatkin, Eugene A., and Suelynn E. Ren. "MDMA, Methylone, and MDPV: Drug-Induced Brain Hyperthermia and Its Modulation by Activity State and Environment." In Neuropharmacology of New Psychoactive Substances (NPS). Springer International Publishing, 2016. http://dx.doi.org/10.1007/7854_2016_35.

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Irvine, William M. "Methylene." In Encyclopedia of Astrobiology. Springer Berlin Heidelberg, 2014. http://dx.doi.org/10.1007/978-3-642-27833-4_1808-4.

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Irvine, William M. "Methylene." In Encyclopedia of Astrobiology. Springer Berlin Heidelberg, 2015. http://dx.doi.org/10.1007/978-3-662-44185-5_1808.

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Irvine, William M. "Methylene." In Encyclopedia of Astrobiology. Springer Berlin Heidelberg, 2011. http://dx.doi.org/10.1007/978-3-642-11274-4_1808.

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Gooch, Jan W. "Methylene Blue." In Encyclopedic Dictionary of Polymers. Springer New York, 2011. http://dx.doi.org/10.1007/978-1-4419-6247-8_7416.

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Gooch, Jan W. "Methylene Chloride." In Encyclopedic Dictionary of Polymers. Springer New York, 2011. http://dx.doi.org/10.1007/978-1-4419-6247-8_7417.

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Gooch, Jan W. "Methylene Group." In Encyclopedic Dictionary of Polymers. Springer New York, 2011. http://dx.doi.org/10.1007/978-1-4419-6247-8_7418.

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Mehlhorn, Heinz. "Methylene Blue." In Encyclopedia of Parasitology. Springer Berlin Heidelberg, 2016. http://dx.doi.org/10.1007/978-3-662-43978-4_4062.

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Mehlhorn, Heinz. "Methylene Blue." In Encyclopedia of Parasitology. Springer Berlin Heidelberg, 2015. http://dx.doi.org/10.1007/978-3-642-27769-6_4062-1.

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Clifton, Jack, and Jerrold B. Leikin. "Methylene Blue." In Critical Care Toxicology. Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-17900-1_161.

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Trabalhos de conferências sobre o assunto "Methylone"

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Pires, Filipa, Margarida Coelho, Paulo A. Ribeiro, and Maria Raposo. "Methylene Blue." In Special Session on Advanced Optical Materials. SCITEPRESS - Science and Technology Publications, 2016. http://dx.doi.org/10.5220/0005843303790383.

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Kornhauser, Alan A. "Aqua-Ammonia as an Environmentally Acceptable Low Temperature Brine." In ASME 2011 International Mechanical Engineering Congress and Exposition. ASMEDC, 2011. http://dx.doi.org/10.1115/imece2011-62684.

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In many industrial processes, cooling with brines is preferable to cooling with an evaporating refrigerant. For medium and high temperatures (above about −35°C/−30°F), aqueous solutions of calcium chloride, sodium chloride, ethylene glycol, propylene glycol, and methanol have typically been used. For very low temperatures (down to about −80°C/-110°F) halocarbon refrigerants methylene chloride and trichloroethylene have generally been used. In recent years, both methylene chloride and trichloroethylene have come under increasingly strict regulation because of their toxicity. While many plants c
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Macaulay, Erin C., Hester E. Roberts, Suzan Al-Momani, et al. "Methylome meets maternity ward." In BCB '15: ACM International Conference on Bioinformatics, Computational Biology and Biomedicine. ACM, 2015. http://dx.doi.org/10.1145/2808719.2811419.

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Saltonstall, Christopher B., John C. Duda, Patrick E. Hopkins, and Pamela M. Norris. "Assesment of Vibrational Coupling at Solid-SAM Junctions." In ASME/JSME 2011 8th Thermal Engineering Joint Conference. ASMEDC, 2011. http://dx.doi.org/10.1115/ajtec2011-44314.

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Self-assembled monolayers (SAMs) have recently garnered much interest due to their unique electrical and chemical properties. The limited literature detailing SAM thermal properties has suggested that thermal boundary conductance (TBC) at solid-SAM junctions is not only low, but also insensitive to changes in SAM length as the number of methylene groups (-CH2-) along alkanedithiol chains is varied from 8 to 10. The present study investigates the vibrational spectra of alkanedithiol SAMs as a function of the number of methylene groups forming the molecule backbone via Hartree-Fock methods and t
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Hofacker, Scott A. "Non-Methylene Chloride Paint Removers." In SAE Airframe/Engine Maintenance & Repair Conference & Exposition. SAE International, 1998. http://dx.doi.org/10.4271/983117.

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Rosa, G. S., B. D. Zorzi, K. Machry, P. Krolow, C. M. Moura, and E. G. Oliveira. "Experimental investigation of drying of malt bagasse." In 21st International Drying Symposium. Universitat Politècnica València, 2018. http://dx.doi.org/10.4995/ids2018.2018.7785.

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The aim of this work was to investigate the convective drying process of malt bagasse and to evaluate the influence of this process on the application of this residue as adsorbent in methylene blue removel by adsorption process. The experimental system for drying was a fixed bed dryer with parallel airflow, with operating conditions: air temperature in the range of 40 to 90 oC and air veocity of 2 m/s. The adsorption experiments were perfomed with solution of methylene blue at 70 ppm concentration. The drying kinetics showed a constant drying rate period followed by a falling drying rate. The
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Repici, A., C. Hassan, R. Bisschops, et al. "METHYLENE BLUE-MMX FOR SCREENING COLONOSCOPY." In ESGE Days 2019. Georg Thieme Verlag KG, 2019. http://dx.doi.org/10.1055/s-0039-1681506.

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Genina, Elina A., Alexey N. Bashkatov, and Valery V. Tuchin. "Methylene blue diffusion in skin tissue." In SPIE Proceedings, edited by Ruikang K. Wang, Jeremy C. Hebden, Alexander V. Priezzhev, and Valery V. Tuchin. SPIE, 2004. http://dx.doi.org/10.1117/12.572047.

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Fujiwara, Tamio, Hiroshi Ohue, and Takumi Urata. "Demonstration of the Enhanced Mixing and Reaction Ability of an Alternate Pumping Microreactor With Visualization of the Mixing Field and the Reaction Field." In ASME 2010 8th International Conference on Nanochannels, Microchannels, and Minichannels collocated with 3rd Joint US-European Fluids Engineering Summer Meeting. ASMEDC, 2010. http://dx.doi.org/10.1115/fedsm-icnmm2010-30059.

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In order to enhance the mixing and reaction capabilities of micromixers and microreactors, we had proposed a novel system termed alternate pumping microreactor (APMR) and had demonstrated that the APMR could generate a thin-layered structure under a particular pumping condition. This flow pattern should enhance the abovementioned capabilities. In this paper, we visualized the dilution process of methylene blue solution with water in the APMR and established a method to obtained the concentration field from the captured image according to the relation between the methylene blue concentration an
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Zhang, Xiheng, Li Zhang, Liwei Hou, and Lihua Dong. "Persulfate-enhanced Photocatalytic Degradation of Methylene Blue." In 2016 5th International Conference on Sustainable Energy and Environment Engineering (ICSEEE 2016). Atlantis Press, 2016. http://dx.doi.org/10.2991/icseee-16.2016.111.

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Relatórios de organizações sobre o assunto "Methylone"

1

Mhike, Morgen. Characterization of Methylene Diphenyl Diisocyanate Protein Conjugates. Portland State University Library, 2000. http://dx.doi.org/10.15760/etd.1843.

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2

DuBois, D. A., and R. H. Neilson. Addition Reactions of a Silylated Imino(Methylene)Phosphorane. Defense Technical Information Center, 1989. http://dx.doi.org/10.21236/ada203987.

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3

Alcaraz, A., R. L. Ward, S. S. Hulsey, and B. D. Andresen. A preliminary study of extraction solvents for CW-agents and their decomposition products [3:1 (methylene chloride:isopropanol) vs. methylene chloride]. Office of Scientific and Technical Information (OSTI), 1994. http://dx.doi.org/10.2172/71303.

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Salerno, R. F., J. V. Dichiaro, E. E. Egleston, and J. W. Koons. An investigation of nonchlorinated substitute cleaning agents for methylene chloride. Office of Scientific and Technical Information (OSTI), 1990. http://dx.doi.org/10.2172/5061449.

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Pesce-Rodriguez, Rose. Solubility of RDX, PETN and Boric Acid in Methylene Chloride. Defense Technical Information Center, 2010. http://dx.doi.org/10.21236/ada532998.

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Vassileva, Paunka, Dimitrinka Voykova, Ivan Uzunov, and Snejanka Uzunova. Methylene Blue Adsorption by Triticum monococcum L. Husks Based Materials. "Prof. Marin Drinov" Publishing House of Bulgarian Academy of Sciences, 2018. http://dx.doi.org/10.7546/crabs.2018.09.05.

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Luey, K. T., D. J. Coleman, and G. K. Ternet. Replacement of Methylene Chloride in NVR and Paint Removal Applications. Defense Technical Information Center, 2000. http://dx.doi.org/10.21236/ada387567.

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Boddu, Veera, Marsha T. Dunstan, Michelle Hanson, et al. Evaluation of Methylene Chloride Emission Control Technologies at Anniston Army Depot. Defense Technical Information Center, 2007. http://dx.doi.org/10.21236/ada590999.

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Author, Not Given. Molecular Quantum Mechanics 2010: From Methylene to DNA and Beyond Conference Support. Office of Scientific and Technical Information (OSTI), 2013. http://dx.doi.org/10.2172/1079680.

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Tollison, Kerri, Greg Drake, Tom Hawkins, Adam Brand, and Milton McKay. The Synthesis and Characterization of Methylene Bisoxyamine CH2(-O-NH2)2 Salts. Defense Technical Information Center, 2001. http://dx.doi.org/10.21236/ada409718.

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