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Teses / dissertações sobre o tema "Pathology"

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1

Bax, Trent Malcolm. ""Internet addiction" in contemporary China: individual pathology or pathology of normalcy?" Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2011. http://hub.hku.hk/bib/B45815021.

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2

Stuart, Persoons Maria Cornelia Johanna. "Cytomegalovirus and vascular pathology." Maastricht : Maastricht : Universiteit Maastricht ; University Library, Maastricht University [Host], 1998. http://arno.unimaas.nl/show.cgi?fid=8496.

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3

Singh, Mark. "D6 in cutaneous pathology." Thesis, University of Glasgow, 2013. http://theses.gla.ac.uk/4636/.

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Chemokines are central to the migration of leukocytes around the body, during both inflammatory and homeostatic conditions. Chemokines mediate their effects by binding to chemokine receptors found on the migrating cell’s surface. Chemokine binding to the chemokine receptor results in signaling, which allows the cell to migrate towards the epicenter of chemokine production. In addition to ‘classical’ chemokine receptors which are involved in leukocyte migration, a discrete family of chemokine receptors exist which are considered to be ‘atypical’, as binding to their cognate ligands does not res
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4

Dougherty, Janis Ruden Ronald A. "The pathology of addiction /." Online version of thesis, 2009. http://hdl.handle.net/1850/11763.

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5

Kubarych, Thomas. "Narcissism, personality and personality pathology." Thesis, University of Edinburgh, 1999. http://hdl.handle.net/1842/28380.

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This thesis used the methods of differential, cognitive and theoretical psychology to investigate the relationships between pathology narcissism and maladaptive personality and behaviour in general, and to attempt the beginnings of construct validation of M. Scott Peck's proposed 'evil' subtype of the DSM-IV Narcissistic Personality Disorder in particular. After a review of theoretical and empirical contributions to the psychology of narcissism, two empirical studies were conducted. In the first, joint self-report survey research using 338 subjects investigated the psychometric structure of na
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6

Wu, Bing. "Pathology of rotator cuff tendonopathy." University of Western Australia. Centre for Orthopaedic Research, 2009. http://theses.library.uwa.edu.au/adt-WU2010.0032.

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Tendonopathy, resulting in the loss of mechanical strength of a tendon, is a serious health problem affecting many people. The common symptom of tendonopathy is pain – patients' daily activities, their participation in sport and exercise, and their ability to work are greatly compromised. Tendonopathy is considered to be a degenerative disorder caused by repetitive injury of the tendon. The most common tendon lesions are Achilles tendon rupture, lateral epicondylitis (tennis elbow) and rotator cuff tear. However, in spite of its clinical significance, our knowledge about tendonopathy is still
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7

Goszer, Libby. "Adolescent suicidality and attachment pathology." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1998. http://www.collectionscanada.ca/obj/s4/f2/dsk2/tape15/PQDD_0027/NQ37706.pdf.

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8

Bruijn, Lambertus Matthias de. "Automatic classification of pathology reports." [Maastricht : Maastricht : Universiteit Maastricht] ; University Library, Maastricht University [Host], 1997. http://arno.unimaas.nl/show.cgi?fid=5936.

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9

Kee, Francis. "Molecular pathology of hepatocellular carcinoma." Click to view the E-thesis via HKUTO, 2008. http://sunzi.lib.hku.hk/hkuto/record/b40203785.

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10

Roe, Thomas John Kelsey. "TGFβ in protection and pathology." Thesis, Imperial College London, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.406711.

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11

Lee, Martin A. "Imaging pathology in multiple sclerosis." Thesis, University of Oxford, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.312191.

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12

Kee, Francis, and 紀思思. "Molecular pathology of hepatocellular carcinoma." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2008. http://hub.hku.hk/bib/B40203785.

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13

Gillespie, Karen R. "Molecular pathology of mammary neoplasia." Thesis, Glasgow Caledonian University, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.243533.

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14

Clark, Thomas Justin. "Ambulatory diagnosis of endometrial pathology." Thesis, University of Birmingham, 2003. http://etheses.bham.ac.uk//id/eprint/214/.

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The aim of this thesis was to determine the diagnostic accuracy of outpatient endometrial evaluation using endometrial biopsy (EB), ultrasound scan (USS) and hysteroscopy (OPH) by conducting systematic quantitative reviews of the published literature. The optimum diagnostic strategy in terms of cost-effectiveness (cost per life year gained), was then established for the investigation of women with post-menopausal bleeding (PMB) for endometrial cancer, using the review data in a decision analysis designed to reflect current service provision. Meta-analyses showed that a positive test result fol
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15

Verleyen, Wim. "Machine learning for systems pathology." Thesis, University of St Andrews, 2013. http://hdl.handle.net/10023/4512.

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Systems pathology attempts to introduce more holistic approaches towards pathology and attempts to integrate clinicopathological information with “-omics” technology. This doctorate researches two examples of a systems approach for pathology: (1) a personalized patient output prediction for ovarian cancer and (2) an analytical approach differentiates between individual and collective tumour invasion. During the personalized patient output prediction for ovarian cancer study, clinicopathological measurements and proteomic biomarkers are analysed with a set of newly engineered bioinformatic tool
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16

Petropoulos, Ioannis. "Corneal nerve pathology in diabetes." Thesis, University of Manchester, 2013. https://www.research.manchester.ac.uk/portal/en/theses/corneal-nerve-pathology-in-diabetes(9912e560-1032-45cd-8f0a-0477d6605a98).html.

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The accurate detection and quantification of human diabetic somatic polyneuropathy (DSPN) are important to define at risk patients, anticipate deterioration, and assess new therapies. Current methods lack sensitivity, require expert assessment and have major shortcomings when employed to define therapeutic efficacy. In recent years, in vivo corneal confocal microscopy (IVCCM) has shown potential as a surrogate endpoint for DSPN.This study aims to investigate fundamental aspects of IVCCM such as repeatability and optimal scanning methodology and establish changes in corneal nerve morphology in
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17

Pryor, Wendy. "Pathology, professionalism, portfolios and progress." Thesis, The University of Sydney, 2010. http://hdl.handle.net/2123/7296.

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Abstract Community-driven standards of professionalism must be addressed, worldwide, at all levels of medical education. The imperative to implement robust strategies to ensure that doctors embrace these standards to justify the autonomy afforded to the medical profession has been a key concern of specialist medical colleges in recent years. Pathologists face unique challenges. Rapid technological change and increasing commercialisation have distanced them further than ever before from patients and other clinicians, resulting in negative stereotypes that impede understanding of professional ro
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18

Lam, Alfred. "Molecular Pathology of Oesophageal Tumours." Thesis, Griffith University, 2006. http://hdl.handle.net/10072/365187.

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Oesophageal tumours are very common worldwide. This thesis aims to delineate the clinicopathological features and molecular biology of oesophageal tumours in Hong Kong Chinese. Over a 30-year study period, oesophageal tumours were obtained in the pathology files of the Queen Mary Hospital, Hong Kong. The tumours were prevalent in males and had a modal peak occurrence in the 7th decade. Patients often presented at an advanced stages. At autopsy, the prevalence of incidental oesophageal cancers and early-stage cancers were low. Many histological subtypes of oesophageal cancers were noted and wer
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19

Karthikeyan, Shanmugam. "Management of rotator cuff pathology." Thesis, University of Warwick, 2016. http://wrap.warwick.ac.uk/89698/.

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The rotator cuff refers to a group of four muscles, which arise from the scapula and insert into the head of humerus forming a cuff around the shoulder joint. They contribute to shoulder movements and provide dynamic stability at the shoulder joint. Pathology of the rotator cuff is the commonest cause for shoulder pain and its severity can vary from subacromial impingement to full thickness tears. NSAIDs and corticosteroids are two of the commonest group of drugs used in treating subacromial impingement syndrome but with conflicting evidence about their relative efficacy and risk of complicati
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20

Willemse, Feike. "A colored view on quantitative pathology aspects of true color image analysis in routine pathology /." [S.l. : [Groningen] : s.n.] ; [University Library Groningen] [Host], 1996. http://irs.ub.rug.nl/ppn/143919504.

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21

Harris, Christopher. "Exploring data sharing in pathology through investing the concept of a National Pathology Handbook system /." Leeds : University of Leeds, School of Computer Studies, 2008. http://www.comp.leeds.ac.uk/fyproj/reports/0708/Harris.pdf.

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22

Brennan, Edwin A. "The Relationship between Combat Experience, Veteran Pathology and the Pathology of Their Intimate Partners| What Factors Predict the Pathology of Veterans and Their Intimate Partners." Thesis, Andrews University, 2019. http://pqdtopen.proquest.com/#viewpdf?dispub=13861186.

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<p> Problem Statement: Military members and their family members who are part of the Global War on Terrorism have experienced deployments and war for over sixteen years and with the resulting toll on both the veteran and their intimate partner. As a result, higher levels of pathology, such as PTSD, Anxiety, and Depression have been experienced by this population. While research has studied the effect of combat on military members, very little research has addressed the effects on family members. Further, no research that has been found by this researcher, has addressed the concept of resonatin
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23

Luther, Jill K. Cook James L. "Comprehensive characterization of canine meniscal pathology." Diss., Columbia, Mo. : University of Missouri-Columbia, 2010. http://hdl.handle.net/10355/.

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The entire dissertation/thesis text is included in the research.pdf file; the official abstract appears in the short.pdf file (which also appears in the research.pdf); a non-technical general description, or public abstract, appears in the public.pdf file. Title from PDF of title page (University of Missouri--Columbia, viewed on July 13, 2010). Thesis advisor: James L. Cook "May 2010" Includes bibliographical references.
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24

Avenant, Carina. "Thinking style preferences in communication pathology." Diss., Pretoria : [s.n.], 2001. http://upetd.up.ac.za/thesis/available/etd-03192007-100706.

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25

Schieder, Christian, and Anja Lorenz. "Towards a pathology of social media." Universitätsbibliothek Chemnitz, 2012. http://nbn-resolving.de/urn:nbn:de:bsz:ch1-qucosa-82030.

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The full transformational effects of Social Media have yet to be understood. Alongside its heavily discussed benefits, a number of potentially harmful effects have become apparent lately. Phenomena such as still increasing information overload, cyber-bullying, or loss of identity have been described in recent research literature from various domains. By means of a literature review our paper aims at reviewing, cataloguing and classifying these psychological and social disorders that have been reported to be related to Social Media engagement. We distinguish between active participation in and
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26

Faraj, Lana Akram. "Corneal neovascularisation : evaluation, pathology and treatment." Thesis, University of Nottingham, 2016. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.718466.

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The cornea is the clear window of the eye and its main refractive media. Corneal avascularity is essential to maintain this function, and this is evolutionarily highly conserved. Corneal vascularisation can result from different types of insults, causing reduced vision and posing a threat to the survival of corneal grafts. We prospectively reviewed 165 patients with corneal vascularisation establishing a reproducible classification of corneal vessels. We classified corneal vessels in to young active, old active, mature, partially regressed and regressed vessels. Patterns of vascularisations di
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27

Song, Jina. "Coagulation factor V : pathology and biochemistry." Thesis, University of British Columbia, 2008. http://hdl.handle.net/2429/5595.

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ROLE OF GLU96, ASP1O2 AND ASP111 IN FACTOR V Coagulation factor V activity is unmasked by thrombin-mediated excision of the central B domain resulting in a noncovalent heterodimer, factor Va. To understand the role of individual amino acids in maintaining the Ca²⁺-depenadent subunit interaction, G1u96 (E96A), Asp1O2 (D1O2A) or Asp111 (D111A) were mutated because of known effects on chelator sensitivity. The primary clotting activity of each mutant was reduced by “40%. Demonstrating at least two distinct inhibition mechanisms, only D111A was further inhibited by thrombin pre-treatment consisten
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28

Horak, E. "Pathology of tumour cell host interactions." Thesis, University of Oxford, 1986. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.379940.

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29

Boehm, Ernest Andrew. "Vascular smooth muscle energetics and pathology." Thesis, University of Oxford, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.308677.

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30

Benson, Richard. "The pathology of rotator cuff failure." Thesis, University of London, 2009. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.589763.

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Abstract The thesis has two aims. Firstly, to gain a greater understanding of the intrinsic mechanisms involved in rotator cuff pathology and its progression. Secondly, to investigate how outcome after operative intervention may be influenced by the macroscopic and microscopic appearance of the rotator cuff. It has been hypothesis that rotator cuff disease is part of a continuum from impingement, through partial thickness tear and leading to massive rotator cuff tears. The thesis uses this hypothesis to create a model of the stages of rotator cuff failure using the macroscopic appearance of th
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31

Manson, Stephanie C. "The invisible pathology of multiple sclerosis." Thesis, University of Oxford, 2008. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.509990.

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32

Robinson, Kate Louise. "Nutritional pathology during experimental Schistosomiasis mansoni." Thesis, University of Glasgow, 1996. http://theses.gla.ac.uk/4811/.

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33

Murdoch, Iain. "Presynaptic pathology after acute brain injury." Thesis, University of Glasgow, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.340811.

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34

Thornton, Christopher Rowland. "Physiological pathology of clubroot (Plasmodiophora brassicae)." Thesis, University of Sheffield, 1990. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.272496.

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35

Ashton, Gabrielle Halusia Shaw. "The molecular pathology of Kindler syndrome." Thesis, King's College London (University of London), 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.427700.

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36

Knolle, Martin Daniel. "Characterisation of proteinases in pulmonary pathology." Thesis, University of Cambridge, 2013. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.608015.

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37

Friedrich-Nel, Hesta. "Assessment innovation in Radiographic Pathology II." Journal for New Generation Sciences, Vol 3, Issue 2: Central University of Technology, Free State, Bloemfontein, 2005. http://hdl.handle.net/11462/478.

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Published Article<br>Innovation in teaching and learning compel facilitators to explore creative possibilities in teaching and learning. Consequently innovative assessment has replaced traditional assessment methods in the Radiographic Pathology II module. The use of an appropriate variety of assessment methods or approaches is crucial to enhance and support learning and measure performance. Thus assessment has to change from knowledge acquisition and factual recall to assess more embracing and critical learning outcomes such as problem-solving, communication, attitudes, critical thinking, pro
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38

Jones, Steve. "Eating pathology : beyond traditional psychotherapeutic approaches." Thesis, University of Sheffield, 2017. http://etheses.whiterose.ac.uk/18168/.

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First, a systematic literature review assessed the efficacy of third-wave interventions to treat individuals who have been diagnosed with an eating disorder. Twenty-three studies which cover five forms of intervention were considered - Acceptance and Commitment Therapy, Compassion Focussed Therapy, Dialectical Behaviour Therapy, Mindfulness-Based Interventions, and Schema Therapy. At present, this field of research is in its infancy, as is reflected in the quantity and quality of the studies available for this review. Dialectical Behaviour Therapy appears to be the most robust third-wave inter
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39

Roomi, Md Waheed. "Molecular pathology of rat hepatic nodules." Thesis, University of Surrey, 1987. http://epubs.surrey.ac.uk/847966/.

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The aim of the present study was to characterize the phenomenon of resistance in putative preneoplastic hepatocyte nodules. These hyperplastic nodules are generated during the development of liver cancer in response to chemical carcinogens, and comprise a population of cells from which hepatocellular carcinoma can develop. As hepatocyte nodules grow in an environment that is otherwise toxic they possess a resistant phenotype. To understand this resistance phenomenon at the biochemical level, several phase I and II drug-metabolizing enzymes in the nodules were examined. Initial experiments were
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40

Ropelewski, Philip Edward. "Light-Independent Pathology of Rhodopsin Mislocalization." Case Western Reserve University School of Graduate Studies / OhioLINK, 2020. http://rave.ohiolink.edu/etdc/view?acc_num=case1586965687533716.

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41

Edler, Melissa K. "Alzheimer's disease pathology in aged chimpanzees." Kent State University / OhioLINK, 2016. http://rave.ohiolink.edu/etdc/view?acc_num=kent1461401487.

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42

Dinkelacker, Vera. "Network pathology in temporal lobe epilepsy." Thesis, Paris 6, 2014. http://www.theses.fr/2014PA066156/document.

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Notre vision de l'épilepsie du lobe temporal avec sclérose hippocampique a beaucoup évolué grâce aux techniques de neuroimagerie multimodale. Initialement perçue comme maladie restreinte à la lésion, à savoir la sclérose hippocampique (SH), elle est aujourd'hui considérée comme un modèle de pathologie en réseau. Cette thèse a pour but d'approfondir les caractéristiques du réseau sous tendant cette épilepsie.Nous avons pour cela recueilli des données de connectivité structurelle, d'EEG et de données cognitives chez une cohorte de 44 patient avec SH unilatérale (22 droite, 22 gauche) et chez 28
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43

Laffe, Stacia A. "Eating pathology in relationship to hopelessness." Online version, 2001. http://www.uwstout.edu/lib/thesis/2001/2001laffes.pdf.

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44

Cherry, Shirley J. "Radiographic Pathology of the Skeletal System." Digital Commons @ East Tennessee State University, 2010. https://dc.etsu.edu/etsu-works/2481.

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45

LIONETTI, MARIA CHIARA. "LAMINOPATHIES: PATHOLOGY, CELL MECHANICS ANDENVIRONMENTAL INDUCTION." Doctoral thesis, Università degli Studi di Milano, 2019. http://hdl.handle.net/2434/620532.

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La lamina nucleare (NL) è un reticolo di proteine fibrillari che riveste la superficie interna della membrana nucleare. Essa è principalmente composta da filamenti intermedi di tipo V , chiamati lamìne, e proteine ausiliari ad esse associate (lamin-associated proteins, LAPs). Nei mammiferi le lamìne sono codificate da tre geni : LMNA, che codifica per la lamìna A e lamìna C (lamìne di tipo A), LMNB1 e LMNB2 che codificano rispettivamente per la lamìna B1 e B2 (lamìne di tipo B). Lamìne e LAPs si associano a formare una matrice tridimensionale densa e dinamica che stabilisce numerose inte
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46

Glatzel, Markus. "Epidemiology and molecular pathology of prion diseases /." Zürich, 2003. http://opac.nebis.ch/cgi-bin/showAbstract.pl?sys=000253382.

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47

Thorpe, Callum. "Immunity and pathology to Chlamydia pneumoniae infection." Thesis, Imperial College London, 2006. http://hdl.handle.net/10044/1/11264.

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48

Saglani, Sejal. "The pathology of infant and preschool wheeze." Thesis, Imperial College London, 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.430129.

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49

Bridges, Leslie Roy. "Comparative pathology of Alzheimer's disease and CJD." Thesis, University of Leeds, 2007. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.446438.

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50

Branca, Caterina, Darren M. Shaw, Ramona Belfiore, et al. "Dyrk1 inhibition improves Alzheimer's disease-like pathology." WILEY, 2017. http://hdl.handle.net/10150/626504.

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There is an urgent need for the development of new therapeutic strategies for Alzheimer's disease (AD). The dual-specificity tyrosine phosphorylation-regulated kinase-1A (Dyrk1a) is a protein kinase that phosphorylates the amyloid precursor protein (APP) and tau and thus represents a link between two key proteins involved in AD pathogenesis. Furthermore, Dyrk1a is upregulated in postmortem human brains, and high levels of Dyrk1a are associated with mental retardation. Here, we sought to determine the effects of Dyrk1 inhibition on AD-like pathology developed by 3xTg-AD mice, a widely used anim
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