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Bibliografias temáticas / Peptides Synthesis

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Literatura científica selecionada sobre o tema "Peptides Synthesis"

Autor: Grafiati

Publicado: 4 de junho de 2021

Última modificação: 25 de julho de 2025

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Artigos de revistas sobre o assunto "Peptides Synthesis"

1

Padalkar, Tanaji Dnyanadev. "Chemical Synthesis of Peptides." International Journal of Scientific Research 2, no. 2 (2012): 147–49. http://dx.doi.org/10.15373/22778179/feb2013/49.

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2

Kang, Taek Jin, and Hiroaki Suga. "Ribosomal synthesis of nonstandard peptidesThis paper is one of a selection of papers published in this Special Issue, entitled CSBMCB — Systems and Chemical Biology, and has undergone the Journal's usual peer review process." Biochemistry and Cell Biology 86, no. 2 (2008): 92–99. http://dx.doi.org/10.1139/o08-009.

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It is well known that standard peptides, which comprise proteinogenic amino acids, can act as specific chemical probes to target proteins with high affinity. Despite this fact, a number of peptide drug leads have been abandoned because of their poor cell permeability and protease instability. On the other hand, nonstandard peptides isolated as natural products often exhibit remarkable pharmaco-behavior and stability in vivo. Although it is likely that numerous nonstandard therapeutic peptides capable of recognizing various targets could have been synthesized, enzymes for nonribosomal peptide s

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3

Tanaka, Masayoshi, Shogo Saito, Reo Kita, et al. "Array-Based Screening of Silver Nanoparticle Mineralization Peptides." International Journal of Molecular Sciences 21, no. 7 (2020): 2377. http://dx.doi.org/10.3390/ijms21072377.

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The use of biomolecules in nanomaterial synthesis has received increasing attention, because they can function as a medium to produce inorganic materials in ambient conditions. Short peptides are putative ligands that interact with metallic surfaces, as they have the potential to control the synthesis of nanoscale materials. Silver nanoparticle (AgNP) mineralization using peptides has been investigated; however, further comprehensive analysis must be carried out, because the design of peptide mediated-AgNP properties is still highly challenging. Herein, we employed an array comprising 200 spot

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4

Mourtas, Spyridon, Christina Katakalou, Dimitrios Gatos, and Kleomenis Barlos. "Convergent Synthesis of Thioether Containing Peptides." Molecules 25, no. 1 (2020): 218. http://dx.doi.org/10.3390/molecules25010218.

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Thioether containing peptides were obtained following three synthetic routes. In route A, halo acids esterified on 2-chlorotrityl(Cltr) resin were reacted with N-fluorenylmethoxycarbonyl (Fmoc) aminothiols. These were either cleaved from the resin to the corresponding (Fmoc-aminothiol)carboxylic acids, which were used as key building blocks in solid phase peptide synthesis (SPPS), or the N-Fmoc group was deprotected and peptide chains were elongated by standard SPPS. The obtained N-Fmoc protected thioether containing peptides were then condensed either in solution, or on solid support, with th

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5

Ayat, Abbood. "Insights into Therapeutic Peptides and their Quality Control." International Journal of Advanced Pharmaceutical Sciences and Research (IJAPSR) 5, no. 1 (2024): 20–27. https://doi.org/10.54105/ijapsr.A4061.05011224.

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<strong>Abstract:</strong> Therapeutic peptides have been garnering renewed attention in recent years. The manufacturing of peptides and protein-based drugs rapidly expands within the pharmaceutical sector. These compounds may be obtained through solid-phase synthesis or biotechnological methods. Peptides and proteins are delicate molecules that undergo chemical or physical changes such as oxidation of methionine, deamidation of asparagine and glutamine, isomerization, aggregation, and denaturation during production. The alterations could compromise the stability of the drugs, consequently imp

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6

Perumal, Pandurangan, and Vijaya P. Pandey. "Antimicrobial peptides: the role of hydrophobicity in the alpha helical structure." Journal of Pharmacy & Pharmacognosy Research 1, no. 1 (2013): 39–53. http://dx.doi.org/10.56499/jppres13.005_1.2.39.

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The antimicrobial peptides (AMPs) are a class of molecule obtained from plants, insects, animals, and humans. These peptides have been classified into five categories: 1. Anionic peptide, 2. Linear alpha helical cationic peptide, 3. Cationic peptide, 4. Anionic and cationic peptides with disulphide bonds, and 5. Anionic and cationic peptide fragments of larger proteins. Factors affecting AMPs are sequence, size, charge, hydrophobicity, amphipathicity, structure and conformation. Synthesis of these peptides is convenient by using solid phase peptide synthesis by using FMOC chemistry protocol. T

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7

Liu, Xuejian, Robert B. P. Elmes, and Katrina A. Jolliffe. "Synthesis of Side-Chain Modified Peptides Using Iterative Solid Phase ‘Click' Methodology." Australian Journal of Chemistry 70, no. 2 (2017): 201. http://dx.doi.org/10.1071/ch16567.

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A series of side-chain modified peptides have been prepared via an iterative sequence of peptide couplings and azide–alkyne cycloadditions (‘click’ reactions) using Fmoc-solid phase peptide synthesis. This efficient modular synthetic route allows the systematic and sequential incorporation of a variety of side-chain modifications onto short peptides. The versatility of this approach was demonstrated by the synthesis of a series of short peptides with appended anion recognition motifs and fluorescent indicators.

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8

Yano, Shinya, Toshihiro Mori, and Hideki Kubota. "Silylated Tag-Assisted Peptide Synthesis: Continuous One-Pot Elongation for the Production of Difficult Peptides under Environmentally Friendly Conditions." Molecules 26, no. 12 (2021): 3497. http://dx.doi.org/10.3390/molecules26123497.

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Addition of the silylated tag (STag) enables peptides to be highly soluble in CPME, allowing them to be used at high concentrations in a coupling reaction to enhance reactivity and achieve effective synthesis of sterically hindered peptides. We described the development of a continuous one-pot STag-assisted peptide synthesis platform as a method that provides near-stoichiometric, speedy, environmentally friendly, and scalable peptide synthesis.

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9

Carmona, Adriana K., Maria Aparecida Juliano, and Luiz Juliano. "The use of Fluorescence Resonance Energy Transfer (FRET) peptidesfor measurement of clinically important proteolytic enzymes." Anais da Academia Brasileira de Ciências 81, no. 3 (2009): 381–92. http://dx.doi.org/10.1590/s0001-37652009000300005.

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Proteolytic enzymes have a fundamental role in many biological processes and are associated with multiple pathological conditions. Therefore, targeting these enzymes may be important for a better understanding of their function and development of therapeutic inhibitors. Fluorescence Resonance Energy Transfer (FRET) peptides are convenient tools for the study of peptidases specificity as they allow monitoring of the reaction on a continuous basis, providing a rapid method for the determination of enzymatic activity. Hydrolysis of a peptide bond between the donor/acceptor pair generates fluoresc

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10

Castro, Aaron, Evelyna Derhovanessian, Ulrich Luxemburger, et al. "A Fast, Flexible and Low Cost Process for Neo-Epitope Based Immune Monitoring." Journal of Immunology 198, no. 1_Supplement (2017): 213.5. http://dx.doi.org/10.4049/jimmunol.198.supp.213.5.

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Abstract Advances in genomic technologies have paved the way to developing personalized cancer vaccines targeting neo-antigens. Patient-specific vaccines, targeting several neo-antigens in one go have already entered the clinic. Such personalized, multi-target approach poses a challenge for immune monitoring of vaccine-specific T-cell responses in a fast, flexible and cost-effective fashion. Most immune monitoring protocols use 9–15-mer synthetic peptides originating from the vaccine target antigen. In contrast to detection of shared antigen-specific T-cells, for which the same peptide batch c

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Teses / dissertações sobre o assunto "Peptides Synthesis"

1

Chen, Fei, and 陳飛. "Studies on aminoxy peptides and prebiotic peptide formation." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2006. http://hub.hku.hk/bib/B38534149.

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2

Puchelle, Valentin. "Peptide-polymer conjugates : divergent synthesis from the initiating peptides." Electronic Thesis or Diss., Sorbonne université, 2020. http://www.theses.fr/2020SORUS472.

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L’utilisation de peptides pour des applications biomédicales reste limitée, en raison de leur courte demi-vie biologique. Le greffage de polymères aux peptides a conduit à l’amélioration des propriétés du peptide. Les conjugués peptide-polymère peuvent être synthétisés par méthode convergente ou divergente. Alors que la première approche conduit à de faibles rendements, la deuxième est limitée à la polymérisation de monomères vinyliques. Nous proposons une méthode de synthèse divergente des conjugués, basée sur la fonctionnalisation des liaisons peptidiques, via le greffage de polyéthers. En e

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3

Swenson, Helen Rachel. "Studies in synthetic peptides and heterocyclic synthesis." Thesis, University of Edinburgh, 1999. http://hdl.handle.net/1842/13061.

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The following work documents three studies undertaken using solid phase synthesis techniques. Interaction of the zinc metalloprotease, endothelin converting enzyme-1(ECE-1), with its peptidic natural substrate big endothelum-1 has been investigated via an SAR study, using solid phase peptide synthesis (SPPS). Truncated forms of the substrate had been previously reported to inhibit ECE-1, this was confirmed however the big ET-1 analogues were shown to be substrates for the enzyme. A short study of the substrate specificity of ECE-1 was carried out. The synthesis of vast libraries of peptides us

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4

Dillon, David Lawrence. "Peptide derivatives as pharmaceuticals : synthesis and reactions of n-thioacyl peptides." Thesis, Oxford Brookes University, 1989. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.327912.

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5

Lam, Hiu-yung, and 林曉勇. "Total synthesis of daptomycin and other cyclic peptides via Ser/Thr ligation-mediated peptide cyclization." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2014. http://hdl.handle.net/10722/207198.

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Head-to-tail cyclic peptides with a wide range of ring sizes have been discovered in various organisms including bacteria, fungi, plants and animals. Many of them exhibit remarkable biological activities with high potency. Daptomycin, a cyclic lipodepsipeptide isolated from soil bacteria Stretomyces roseoporus, is the first natural product antibiotic launched in a generation. Daptomycin has potent bactericidal activity against otherwise antibiotic-resistant Gram-positive pathogens including methicillin-resistant Staphylococcus aureus (MRSA), vancomycin-resistant enterococci (VRE) and vancomyci

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6

Corrihons, Fabien. "Solid phase peptide synthesis of cyclic peptides for cancer oncology." Thesis, University of Strathclyde, 2004. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.424312.

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7

Ndung'u, Susan Wanjiru. "The medicinal chemistry of cyclo(D-Phe-2Cl-Pro) and cyclo(Phe-4F-Pro)." Thesis, Nelson Mandela Metropolitan University, 2011. http://hdl.handle.net/10948/7083.

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Although peptides and proteins are considered as lead compounds for the discovery and development of new therapeutic agents, poor metabolic and physical properties have limited their optimisation as drug candidates (Adessi & Soto, 2002). Research by medicinal chemists however, generated the discovery of structural similarities between some peptides and diketopiperazines and the common occurrence of such compounds in natural products. This discovery initiated the synthesis of diketopiperazines from amino acids in an attempt to bypass the previously mentioned limitations of using peptides as dru

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8

Sieber, Stephan Axel. "Nonribosomal peptide synthetases quaternary structure and chemoenzymatic synthesis of macrocyclic peptides /." [S.l.] : [s.n.], 2004. http://archiv.ub.uni-marburg.de/diss/z2004/0218/.

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9

Irving, Stephen L. "Synthesis and purification of peptides." Thesis, University of Edinburgh, 1994. http://hdl.handle.net/1842/28282.

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Improved routes to tetrabenz[<I>a,c,g,i</I>]fluorene derivatives have been developed, allowing the synthesis of N<SUP>α</SUP>-17-tetrabenzo[<I>a,c,g,i</I>]fluorenyl-methoxycarbonyl (tbfmoc) urethane derivatives of alanine, leucine, isoleucine, methionine and valine. The chloroformate and pentafluorophenyl carbonate of 17-tetrabenzo[<I>a,c,g,</I>]fluorenylmethanol have been prepared and used to introduce the base-labile Tbrmoc group onto the N<SUP>α</SUP>-termini of resin-bound peptides. The high affinity of the Tbrmoc group for porous graphitised carbon (PGC) has been exploited for the purific

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10

Alexander, Mcmanamara Linda Mary. "Synthesis of stable - helical peptides." Thesis, University College London (University of London), 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.398920.

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Livros sobre o assunto "Peptides Synthesis"

1

1949-, Basava Channa, and Anantharamaiah G. M. 1947-, eds. Peptides: Design, synthesis, and biological activity. Birkhäuser, 1994.

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2

Sidney, Udenfriend, Meienhofer Johannes, and Smith Clark W, eds. The Peptides: Analysis, synthesis, biology. Academic Press, 1987.

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3

Sidney, Udenfriend, and Meienhofer Johannes, eds. The Peptides: Analysis, synthesis, biology. Academic Press, 1987.

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4

Labsystems Research Symposium on Synthetic Peptides in Biology and Medicine (1985 Hämeenlinna, Finland). Synthetic peptides in biology and medicine: Proceedings of the Labsystems Research Symposium on Synthetic Peptides in Biology and Medicine held in Hämeenlinna, Finland, on June 6-8, 1985. Edited by Alitalo Kari, Partanen Paul, Vaheri Antti, and Labsystems (Firm). Elsevier Science Publishers, 1985.

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5

D, Fricker Lloyd, ed. Peptide biosynthesis and processing. CRC Press, 1991.

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6

Bodanszky, M. The practice of peptide synthesis. 2nd ed. Springer-Verlag, 1994.

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7

International Peptide Symposium (1st 1997 Kyoto, Japan). Peptide science, present, and future. Kluwer Academic, 1999.

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8

Gershkovich, A. A. Sintez peptidov: Reagenty i metody. Nauk. dumka, 1987.

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9

Gershkovich, A. A. Khimicheskiĭ sintez peptidov. Nauk. dumka, 1992.

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10

Buschhaus, Christian. Der p-Nitrophenylethyl- und p-Nitrophenylethoxycarbonyl-Rest als neue Schutzgruppe in der Peptidsynthese. Hartung-Gorre, 1989.

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Capítulos de livros sobre o assunto "Peptides Synthesis"

1

Frank, R., H. Leban, M. Kraft, and H. Gausepohl. "Continuous flow peptide synthesis." In Peptides. Springer Netherlands, 1988. http://dx.doi.org/10.1007/978-94-010-9595-2_63.

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2

Wendlberger, G., W. Göhring, G. Hübener, et al. "Synthesis of human secretin." In Peptides. Springer Netherlands, 1988. http://dx.doi.org/10.1007/978-94-010-9595-2_87.

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3

Xu, Jie-cheng, Ming-zhu Zhang, Shi-yi Liu, and Yi Zhang. "Synthesis of muramyl peptides." In Peptides. Springer Netherlands, 1993. http://dx.doi.org/10.1007/978-94-010-9066-7_75.

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4

Evans, David A., Ann E. Weber, Thomas C. Britton, Jonathan A. Ellman, and Eric B. Sjogren. "Asymmetric synthesis of amino acids." In Peptides. Springer Netherlands, 1988. http://dx.doi.org/10.1007/978-94-010-9595-2_42.

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5

Thorbek, Pia, Jørn Lauridsen, and Fred Widmer. "Protease-catalyzed synthesis of oxytocin." In Peptides. Springer Netherlands, 1988. http://dx.doi.org/10.1007/978-94-010-9595-2_84.

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6

Gruber, S. M., P. Yu-Yang, and S. P. A. Fodor. "Light-directed combinatorial peptide synthesis." In Peptides. Springer Netherlands, 1992. http://dx.doi.org/10.1007/978-94-011-2264-1_187.

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7

Albericio, Fernando, Paul Lloyd-Williams, Margarida Gairí, Gemma Jou, Ramon Eritja, and Ernest Giralt. "Convergent solid-phase peptide synthesis." In Peptides. Springer Netherlands, 1992. http://dx.doi.org/10.1007/978-94-011-2264-1_240.

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8

Kagel, John R., James L. Kofron, and Daniel H. Rich. "Synthesis of 5-fluoroproline derivatives." In Peptides. Springer Netherlands, 1992. http://dx.doi.org/10.1007/978-94-011-2264-1_331.

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9

Wijkmans, J. C. H. M., J. H. van Boom, and W. Bloemhoff. "Peptide synthesis by insertion reactions." In Peptides. Springer Netherlands, 1994. http://dx.doi.org/10.1007/978-94-011-0683-2_39.

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10

Benovitz, D. E., K. Darlak, W. A. Klis, E. Klein, and A. F. Spatola. "Membrane based peptide synthesis (MBPS)." In Peptides. Springer Netherlands, 1994. http://dx.doi.org/10.1007/978-94-011-0683-2_40.

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Trabalhos de conferências sobre o assunto "Peptides Synthesis"

1

Obeyesekere, Nihal, Ali Naraghi, and John S. McMurray. "Synthesis and Evaluation of Biopolymers as Low Toxicity Corrosion Inhibitors for North Sea Oil Fields." In CORROSION 2001. NACE International, 2001. https://doi.org/10.5006/c2001-01049.

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Abstract The paper describes the synthesis and evaluation of a series of environmentally friendly corrosion inhibitors. These products were designed especially to use in North Sea Oil fields and in other environmentally sensitive areas as green inhibitors of CO2 corrosion. More than thirty peptides, some with random amino acid sequences and some ordered copolymers were synthesized by solid phase peptide techniques using the Fmoc/tert-butyl protection strategy. In these syntheses the C-terminal residue was coupled to a resin and peptides were built out either by adding various Fmoc-Xxx-Yyy-Zzz

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2

Obeyesekere, Nihal, and Thusitha Wickramarachchi. "Transition from Combinatorial Chemistry to Present Day Robotics in Product Development for Oil Field Chemicals." In MECC 2023. AMPP, 2023. https://doi.org/10.5006/mecc2023-20245.

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Abstract In this paper, the slow evolution of combinatorial chemistry from its dawn in 1980’s to today’s oil field product development is discussed. Combinatorial chemistry comprises chemical synthetic methods that make it possible to prepare a vast number of compounds in a single process. These compound libraries can be made as mixtures, sets of individual compounds or chemical structures generated by computer software. This phenomenon was first invented by Arpad Furka (Lorand University, Budapest) in 1982. He described the principle of it, the combinatorial synthesis and a deconvolution proc

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3

Stüber, W., H. Pelzer, and N. Heimburger. "INDUCTION OF ANTITHROMBIN III (AT III) ANTIBODIES BY IMMUNIZATION WITH SYNTHETIC PEPTIDES." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1644355.

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The primary structure of AT III was examined in respect of potential antigenic sites. The topics were the determination of the hydrophilicity, hydropathy, acrophilicity and the propensities for alpha-helices, B-turns and 13-sheets. The peptides AT III 21-34, 21-42, 129 - 140, 226 - 240 and 343 -363 were synthesized using the solid phase peptide synthesis methode. The subsequent purification of the crude peptides was achieved by h.p.I.e. or by ion exchange chromatography. The peptides were coupled to keyhole limpet hemocyanine (KLH) via thioether bonds. Antisera against KLH-peptides were raised

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4

Sakakibara, Shumpei. "Solution synthesis of peptides." In Future Aspect in Peptide Chemistry - Ringberg Conference. Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, 1999. http://dx.doi.org/10.1135/css199901001.

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5

Biondi, Barbara, Silvia Millan, Fernando Formaggio, Alessandra Semenzato, and Cristina Peggion. "Synthesis and conformationof short peptides modeled after peptide LL-37." In 35th European Peptide Symposium. Prompt Scientific Publishing, 2018. http://dx.doi.org/10.17952/35eps.2018.195.

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6

Danilin, N. A., A. L. Matveev, A. V. Bardasheva, V. M. Golyshev, and D. S. Novopashina. "PEPTIDE CONJUGATES OF RNASE P INHIBITING OLIGONUCLEOTIDES: SYNTHESIS AND PROPERTIES." In X Международная конференция молодых ученых: биоинформатиков, биотехнологов, биофизиков, вирусологов и молекулярных биологов — 2023. Novosibirsk State University, 2023. http://dx.doi.org/10.25205/978-5-4437-1526-1-311.

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Peptide conjugates of inhibiting bacterial RNase P oligonucleotides were obtained using optimized approaches. The influence of peptides on inhibiting oligonucleotide – RNA-target complex stability, inhibition of RNase P by synthesized conjugates, efficacy of penetration in bacterium A.baumannii and E.coli and their antibacterial activity was investigated.

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7

Hradilek, Martin, Markéta Rinnová, Cyril Bařinka, Milan Souček, and Jan Konvalinka. "Synthesis of library of HIV proteases inhibitors." In VIth Conference Biologically Active Peptides. Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, 1999. http://dx.doi.org/10.1135/css199903079.

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8

Klein, Jens-Uwe, and Václav Čeřovský. "Enzymatic peptide synthesis – simulation of nucleophile excess." In VIth Conference Biologically Active Peptides. Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, 1999. http://dx.doi.org/10.1135/css199903094.

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9

Kistemaker, Hans A. V., Gerbrand J. van der Heden van Noort, Herman S. Overkleeft, Gijsbert A. van der Marel, and Dmitri V. Filippov. "The Synthesis of ADP-Ribosylated Peptides." In The Twenty-Third American and the Sixth International Peptide Symposium. Prompt Scientific Publishing, 2013. http://dx.doi.org/10.17952/23aps.2013.232.

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10

Dzimbova, Tatiana A., Tamara I. Pajpanova, and Evgeny V. Golovinsky. "Synthesis of some sulfoguanidino group-containing amino acids." In VIIIth Conference Biologically Active Peptides. Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, 2003. http://dx.doi.org/10.1135/css200306012.

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Relatórios de organizações sobre o assunto "Peptides Synthesis"

1

Atassi, M. Z. Synthesis and Activity of Oxygen-Carrying Heme Peptides. Defense Technical Information Center, 2004. http://dx.doi.org/10.21236/ada428126.

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2

Atassi, M. Z. Design & Synthesis of Oxygen-Binding Heme Peptides. Defense Technical Information Center, 1990. http://dx.doi.org/10.21236/ada224458.

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3

Vouros, Paul, and Terrance Black. Solid Phase Peptide Synthesis of Antimicrobial Peptides for cell Binding Studies: Characterization Using Mass Spectrometry. Defense Technical Information Center, 2002. http://dx.doi.org/10.21236/ada412571.

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4

Altstein, Miriam, and Ronald Nachman. Rationally designed insect neuropeptide agonists and antagonists: application for the characterization of the pyrokinin/Pban mechanisms of action in insects. United States Department of Agriculture, 2006. http://dx.doi.org/10.32747/2006.7587235.bard.

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The general objective of this BARD project focused on rationally designed insect neuropeptide (NP) agonists and antagonists, their application for the characterization of the mechanisms of action of the pyrokinin/PBAN (PK-PBAN) family and the development of biostable, bioavailable versions that can provide the basis for development of novel, environmentally-friendly pest insect control agents. The specific objectives of the study, as originally proposed, were to: (i) Test stimulatory potencies of rationally designed backbone cyclic (BBC) peptides on pheromonotropic, melanotropic, myotropic and

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Judd, Amrit K. Active Antitoxic Immunization against Ricin Using Synthetic Peptides. Defense Technical Information Center, 1989. http://dx.doi.org/10.21236/adb137490.

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Author, Not Given. [Synthetic adhesive peptides for clinical imaging]. Final report. Office of Scientific and Technical Information (OSTI), 1994. http://dx.doi.org/10.2172/10130310.

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Bredesen, Dale. Novel Synthetic Hunter-Killer Peptides Target and Destroy Prostate Cancer. Defense Technical Information Center, 1999. http://dx.doi.org/10.21236/ada384822.

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Kennedy, Ronald C. Use of Synthetic Peptides Anti-Idiotypes for Controlling Human Immunodeficiency Virus Infection. Defense Technical Information Center, 1992. http://dx.doi.org/10.21236/ada269558.

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Haynes, Barton F. Structural and Functional Studies of Experimental HIV Synthetic Peptide Immunogens. Defense Technical Information Center, 1997. http://dx.doi.org/10.21236/ada333309.

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Crocker, Fiona, Lyndsay Carrigee, Kayla Clark, and Karl Indest. Peptide display for rare earth element binding. Engineer Research and Development Center (U.S.), 2025. https://doi.org/10.21079/11681/49647.

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Resumo:

Rare earth elements (REEs) are metals that are indispensable to the function of many advanced systems and materials. The supply chain of REEs is heavily dependent on foreign sources and supply shortages are a major concern to the US government. Biological recovery approaches could be an economically feasible approach to recover REEs from unconventional or secondary sources. The objective of this project was to express a lanthanide-binding tag, with an affinity for adsorption of REEs, on the surface of the biomining bacterium, Acidithiobacillus ferrooxidans. This was to be accomplished using sy

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