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Artigos de revistas sobre o tema "Periodontal disease Molecular aspects"

Autor: Grafiati

Publicado: 4 de junho de 2021

Última modificação: 30 de janeiro de 2023

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1

AS, Dr Maniyammai, Dr Amudha M, Dr Renuka Devi R, Dr Esther Nalini H, and Dr Arun Kumar Prasad. "Adaptive immune response: Molecular aspects of periodontal disease." International Journal of Applied Dental Sciences 7, no. 4 (October 1, 2021): 89–92. http://dx.doi.org/10.22271/oral.2021.v7.i4b.1356.

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Tsuchida, Sachio. "Proteome Analysis of Molecular Events in Oral Pathogenesis and Virus: A Review with a Particular Focus on Periodontitis." International Journal of Molecular Sciences 21, no. 15 (July 22, 2020): 5184. http://dx.doi.org/10.3390/ijms21155184.

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Some systemic diseases are unquestionably related to periodontal health, as periodontal disease can be an extension or manifestation of the primary disease process. One example is spontaneous gingival bleeding, resulting from anticoagulant treatment for cardiac diseases. One important aspect of periodontal therapy is the care of patients with poorly controlled disease who require surgery, such as patients with uncontrolled diabetes. We reviewed research on biomarkers and molecular events for various diseases, as well as candidate markers of periodontal disease. Content of this review: (1) Intr

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Lin, Peiya, Hiromi Niimi, Yujin Ohsugi, Yosuke Tsuchiya, Tsuyoshi Shimohira, Keiji Komatsu, Anhao Liu, et al. "Application of Ligature-Induced Periodontitis in Mice to Explore the Molecular Mechanism of Periodontal Disease." International Journal of Molecular Sciences 22, no. 16 (August 18, 2021): 8900. http://dx.doi.org/10.3390/ijms22168900.

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Periodontitis is an inflammatory disease characterized by the destruction of the periodontium. In the last decade, a new murine model of periodontitis has been widely used to simulate alveolar bone resorption and periodontal soft tissue destruction by ligation. Typically, 3-0 to 9-0 silks are selected for ligation around the molars in mice, and significant bone loss and inflammatory infiltration are observed within a week. The ligature-maintained period can vary according to specific aims. We reviewed the findings on the interaction of systemic diseases with periodontitis, periodontal tissue d

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Teng, Y. T. A. "Protective and Destructive Immunity in the Periodontium: Part 2—T-cell-mediated Immunity in the Periodontium." Journal of Dental Research 85, no. 3 (March 2006): 209–19. http://dx.doi.org/10.1177/154405910608500302.

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Based on the results of recent research in the field and Part 1 of this article (in this issue), the present paper will discuss the protective and destructive aspects of the T-cell-mediated adaptive immunity associated with the bacterial virulent factors or antigenic determinants during periodontal pathogenesis. Attention will be focused on: (i) osteoimmunology and periodontal disease; (ii) some molecular techniques developed and applied to identify critical microbial virulence factors or antigens associated with host immunity (with Actinobacillus actinomycetemcomitans and Porphyromonas gingiv

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Teng, Y. T. A. "Protective and Destructive Immunity in the Periodontium: Part 1—Innate and Humoral Immunity and the Periodontium." Journal of Dental Research 85, no. 3 (March 2006): 198–208. http://dx.doi.org/10.1177/154405910608500301.

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Based on the results of recent research in the field, the present paper will discuss the protective and destructive aspects of the innate vs. adaptive (humoral and cell-mediated) immunity associated with the bacterial virulent factors or antigenic determinants during periodontal pathogenesis. Attention will be focused on: (i) the Toll-like receptors (TLR), the innate immune repertoire for recognizing the unique molecular patterns of microbial components that trigger innate and adaptive immunity for effective host defenses, in some general non-oral vs. periodontal microbial infections; (ii) T-c

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Divaris, K. "Searching Deep and Wide: Advances in the Molecular Understanding of Dental Caries and Periodontal Disease." Advances in Dental Research 30, no. 2 (October 21, 2019): 40–44. http://dx.doi.org/10.1177/0022034519877387.

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During the past decades, remarkable progress has been made in the understanding of the molecular basis of the 2 most common oral diseases, dental caries and periodontal disease. Improvements in our knowledge of the diseases’ underlying biology have illuminated previously unrecognized aspects of their pathogenesis. Importantly, the key role of the oral (supragingival and subgingival) microbiome is now well recognized, and both diseases are now best understood as dysbiotic. From a host susceptibility standpoint, some progress has been made in dissecting the “hyperinflammatory” trait and other pa

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Elmallawany, Marwa A., Marwa Ahmed EL-Dardiry, Reham K. Nahnoush, Mohamed Akmal, Adam A. Afife, and Mohamed S. Badr. "Structural and Genetic Diversity of Entamoeba gingivalis Trophozoites Isolated from Diseased and Healthy Periodontal Sites." Open Access Macedonian Journal of Medical Sciences 10, A (February 25, 2022): 661–67. http://dx.doi.org/10.3889/oamjms.2022.8713.

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BACKGROUND: At present, there is little documented about the variability aspects of Entamoeba gingivalis (E. gingivalis) in relation to periodontal diseases. This is perhaps due to several specialists rejecting the notion that E. gingivalis can cause periodontal disease. AIM: The aim of the present study was to compare the morphological and genetic variability within trophozoites isolated from diseased (n = 26) and healthy periodontal sites (n = 14). METHODS: Detailed microscopic analyses were performed, in addition to post real-time polymerase chain reaction 18S-SSU rRNA gene scanning technol

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Elgezawi, Moataz, Rasha Haridy, Khalid Almas, Moamen A. Abdalla, Omar Omar, Hatem Abuohashish, Abeer Elembaby, Uta Christine Wölfle, Yasir Siddiqui, and Dalia Kaisarly. "Matrix Metalloproteinases in Dental and Periodontal Tissues and Their Current Inhibitors: Developmental, Degradational and Pathological Aspects." International Journal of Molecular Sciences 23, no. 16 (August 11, 2022): 8929. http://dx.doi.org/10.3390/ijms23168929.

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Objectives: This review article aims to describe some of the roles of Matrix metalloproteinases (MMPs) in enamel, dentine, dental caries, hybrid layer degradation, pulp and periodontal tissues, throwing light on their current inhibitors. The article addresses the potential of MMPs to serve as biomarkers with diagnostic and therapeutic value. Design: The sections of this review discuss MMPs’ involvement in developmental, remodeling, degradational and turnover aspects of dental and periodontal tissues as well as their signals in the pathogenesis, progress of different lesions and wound healing o

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Dieterle, Martin Philipp, Ayman Husari, Thorsten Steinberg, Xiaoling Wang, Imke Ramminger, and Pascal Tomakidi. "From the Matrix to the Nucleus and Back: Mechanobiology in the Light of Health, Pathologies, and Regeneration of Oral Periodontal Tissues." Biomolecules 11, no. 6 (May 31, 2021): 824. http://dx.doi.org/10.3390/biom11060824.

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Among oral tissues, the periodontium is permanently subjected to mechanical forces resulting from chewing, mastication, or orthodontic appliances. Molecularly, these movements induce a series of subsequent signaling processes, which are embedded in the biological concept of cellular mechanotransduction (MT). Cell and tissue structures, ranging from the extracellular matrix (ECM) to the plasma membrane, the cytosol and the nucleus, are involved in MT. Dysregulation of the diverse, fine-tuned interaction of molecular players responsible for transmitting biophysical environmental information into

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Srimaneepong, Viritpon, Artak Heboyan, Muhammad Sohail Zafar, Zohaib Khurshid, Anand Marya, Gustavo V. O. Fernandes, and Dinesh Rokaya. "Fixed Prosthetic Restorations and Periodontal Health: A Narrative Review." Journal of Functional Biomaterials 13, no. 1 (February 1, 2022): 15. http://dx.doi.org/10.3390/jfb13010015.

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Periodontal health plays an important role in the longevity of prosthodontic restorations. The issues of comparative assessment of prosthetic constructions are complicated and not fully understood. The aim of this article is to review and present the current knowledge regarding the various technical, clinical, and molecular aspects of different prosthetic biomaterials and highlight the interactions between periodontal health and prosthetic restorations. Articles on periodontal health and fixed dental prostheses were searched using the keywords “zirconium”, “CAD/CAM”, “dental ceramics”, “metal–

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Obradović, Vesna. "The role of oxidative stress and antioxidant defence system in periodontitis." Medicinski casopis 54, no. 2 (2020): 75–82. http://dx.doi.org/10.5937/mckg54-24883.

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The prevalence of periodontal disease is very high in the adult population. According to research results, as much as 46% of the total population was affected by periodontal disease in the period from 2010 to 2012, which would mean that 64.7 million people had periodontitis, of which 8% had a severe form of this disease. Having in mind the clinical and socioeconomic significance of periodontitis, this review aims to present in a comprehensive way the pathogenetic aspects of periodontitis with a special emphasis on oxidative stress and antioxidant protection mechanisms as possible molecular mec

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Guimarães, Morgana R., Sabrina Garcia de Aquino, Leila S. Coimbra, Luis C. Spolidorio, Keith L. Kirkwood, and Carlos Rossa. "Curcumin modulates the immune response associated with LPS-induced periodontal disease in rats." Innate Immunity 18, no. 1 (January 17, 2011): 155–63. http://dx.doi.org/10.1177/1753425910392935.

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Curcumin is a plant-derived dietary spice ascribed various biological activities. Curcumin therapeutic applications have been studied in a variety of conditions, but not on periodontal disease. Periodontal disease is a chronic inflammatory condition initiated by an immune response to micro-organisms of the dental biofilm. Experimental periodontal disease was induced in rats by injecting LPS in the gingival tissues on the palatal aspect of upper first molars (30 µg LPS, 3 times/week for 2 weeks). Curcumin was administered to rats daily via oral gavage at 30 and 100 mg/kg body weight. Reverse tr

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Nawrot-Hadzik, Izabela, Adam Matkowski, Paweł Kubasiewicz-Ross, and Jakub Hadzik. "Proanthocyanidins and Flavan-3-ols in the Prevention and Treatment of Periodontitis—Immunomodulatory Effects, Animal and Clinical Studies." Nutrients 13, no. 1 (January 15, 2021): 239. http://dx.doi.org/10.3390/nu13010239.

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This paper continues the systematic review on proanthocyanidins and flavan-3-ols in the prevention and treatment of periodontal disease and covers the immunomodulatory effects, and animal- and clinical studies, while the other part discussed the direct antibacterial properties. Inflammation as a major response of the periodontal tissues attacked by pathogenic microbes can significantly exacerbate the condition. However, the bidirectional activity of phytochemicals that simultaneously inhibit bacterial proliferation and proinflammatory signaling can provide a substantial alleviation of both cau

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de Molon, Rafael Scaf, Carlos Rossa Jr., Rogier M. Thurlings, Joni Augusto Cirelli, and Marije I. Koenders. "Linkage of Periodontitis and Rheumatoid Arthritis: Current Evidence and Potential Biological Interactions." International Journal of Molecular Sciences 20, no. 18 (September 13, 2019): 4541. http://dx.doi.org/10.3390/ijms20184541.

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The association between rheumatoid arthritis (RA) and periodontal disease (PD) has been the focus of numerous investigations driven by their common pathological features. RA is an autoimmune disease characterized by chronic inflammation, the production of anti-citrullinated proteins antibodies (ACPA) leading to synovial joint inflammation and destruction. PD is a chronic inflammatory condition associated with a dysbiotic microbial biofilm affecting the supporting tissues around the teeth leading to the destruction of mineralized and non-mineralized connective tissues. Chronic inflammation asso

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Patil, Shankargouda, Hassan A. Sumayli, Alnomari Sultan, Majed A. Hazazi, Majed H. Mashi, Ali YJ Mobarki, Maryam S. Ali Hadi, Huthyfah Mohammed Abulqasim, and Bandar Mohammed M. Thubab. "COVID-19 and Periodontitis: A Reality to Live with." Journal of Contemporary Dental Practice 21, no. 12 (2020): 1398–403. http://dx.doi.org/10.5005/jp-journals-10024-2961.

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ABSTRACT Background Coronavirus disease-19 (COVID-19) is a recent pandemic that is advancing at a rapid rate. The future course of the disease includes severe respiratory infection and also leads to death if unattended. Meticulous measures are necessary before attending any patient. The dental operatories and the clinic surroundings must be well sanitized so as to prevent the spread of pandemic. Aim and objective This review discusses in brief about the pathophysiology and course of COVID-19. Further, we discussed in detail the management aspects of patients in periodontal perspective and the

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Tonoyan, Lilit, Séverine Vincent-Bugnas, Charles-Vivien Olivieri, and Alain Doglio. "New Viral Facets in Oral Diseases: The EBV Paradox." International Journal of Molecular Sciences 20, no. 23 (November 22, 2019): 5861. http://dx.doi.org/10.3390/ijms20235861.

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The oral cavity contributes to overall health, psychosocial well-being and quality of human life. Oral inflammatory diseases represent a major global health problem with significant social and economic impact. The development of effective therapies, therefore, requires deeper insights into the etiopathogenesis of oral diseases. Epstein–Barr virus (EBV) infection results in a life-long persistence of the virus in the host and has been associated with numerous oral inflammatory diseases including oral lichen planus (OLP), periodontal disease and Sjogren’s syndrome (SS). There is considerable evi

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Uitto, Veli-Jukka, and Hannu Larjava. "Extracellular Matrix Molecules and their Receptors: An Overview with Special Emphasis on Periodontal Tissues." Critical Reviews in Oral Biology & Medicine 2, no. 3 (July 1991): 323–54. http://dx.doi.org/10.1177/10454411910020030301.

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Knowledge of extracellular matrix molecules and their cell receptors has increased exponentially during the last 2 decades. It is now known that the structure and function of each tissue is based on specific combinations of matrix molecules. The major constituents of the extracellular matrix are collagens, proteoglycans, and adhesive glycoproteins. The rapid development of biochemical, molecular biological, and immunological research has revealed a lot of interesting details pertaining to these molecules. Several new collagen types have been discovered. In addition to being responsible for the

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DeCarlo, Arthur A., Mayuri Paramaesvaran, Peter L. W. Yun, Charles Collyer, and Neil Hunter. "Porphyrin-Mediated Binding to Hemoglobin by the HA2 Domain of Cysteine Proteinases (Gingipains) and Hemagglutinins from the Periodontal Pathogen Porphyromonas gingivalis." Journal of Bacteriology 181, no. 12 (June 15, 1999): 3784–91. http://dx.doi.org/10.1128/jb.181.12.3784-3791.1999.

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ABSTRACT Heme binding and uptake are considered fundamental to the growth and virulence of the gram-negative periodontal pathogenPorphyromonas gingivalis. We therefore examined the potential role of the dominant P. gingivalis cysteine proteinases (gingipains) in the acquisition of heme from the environment. A recombinant hemoglobin-binding domain that is conserved between two predominant gingipains (domain HA2) demonstrated tight binding to hemin (Kd = 16 nM), and binding was inhibited by iron-free protoporphyrin IX (Ki = 2.5 μM). Hemoglobin binding to the gingipains and the recombinant HA2 (r

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Niederman, Richard, Jie Zhang, and Shelby Kashket. "Short-Chain Carboxylic-Acid-Stimulated, PMN-Mediated Gingival Inflammation." Critical Reviews in Oral Biology & Medicine 8, no. 3 (July 1997): 269–90. http://dx.doi.org/10.1177/10454411970080030301.

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This communication reviews the effects of short-chain carboxylic acids on human cells of importance to the periodontium. The central hypothesis is that these acids can alter both cell function and gene expression, and thus contribute to the initiation and prolongation of gingival inflammation. Short-chain carboxylic acids [CH3-(CH2)x-COOH, x < 3] are metabolic intermediates with a broad range of apparently paradoxical biological effects. For example, lactic acid (CH3-CHOH-COOH), a 3-carbon alpha-hydroxy-substituted acid, is widely recognized for its cariogenicity. Lactic acid, however, also

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., Vishal,, Rampershad ., Ali Raza, Ghulam Nabi Memon, Muhammad Waleed Vohra, and Suneel Kumar Punjabi. "Comparing the Difference on Inflow of Patients in Oral and Maxillofacial Surgery Department before and During Covid-19." Pakistan Journal of Medical and Health Sciences 16, no. 8 (August 31, 2022): 512–13. http://dx.doi.org/10.53350/pjmhs22168512.

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Objective: To Compare the difference on the inflow of patients before and during COVID-19 on the patients presented at oral & maxillofacial surgery at Advance Dental Care Centre, Liaquat University of Medical and Health Sciences Materials &Methods: Medical statistics have been collected for the patients who visited the Advance dental care centre, Liaquat university of medical and health sciences between 1 January 2019 and 31 December 2020. The data collected included age, gender, and extraction of teeth. SPSS version 20.0 was used for the statistical analysis. Results: Of all the patie

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Martellacci, Leonardo, Gianluca Quaranta, Romeo Patini, Gaetano Isola, Patrizia Gallenzi, and Luca Masucci. "A Literature Review of Metagenomics and Culturomics of the Peri-implant Microbiome: Current Evidence and Future Perspectives." Materials 12, no. 18 (September 17, 2019): 3010. http://dx.doi.org/10.3390/ma12183010.

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Background and objectives: In recent years, many different culture-independent molecular techniques have been developed with the aim of investigating the not yet cultivated part of the resident flora of the oral cavity and of analyzing the peri-implant and periodontal flora both in healthy and diseased sites. The most used technologies are Roche 454 pyrosequencing, Illumina HiSeq/MiSeq, ABI SOLiD and Ion Torrent. Due to these methods, two different approaches are available: Metagenomics and the 16S gene analysis. A complementary strategy was also recently developed: Culturomics. Culturomics co

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Zhang, Ping, Jianzhong Liu, Qingan Xu, Gregory Harber, Xu Feng, Suzanne M. Michalek та Jenny Katz. "TLR2-dependent Modulation of Osteoclastogenesis by Porphyromonas gingivalis through Differential Induction of NFATc1 and NF-κB". Journal of Biological Chemistry 286, № 27 (12 травня 2011): 24159–69. http://dx.doi.org/10.1074/jbc.m110.198085.

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Osteolytic diseases, including rheumatoid arthritis, osteomyelitis, and periodontitis, are usually associated with bacterial infections. However, the precise mechanisms by which bacteria induce bone loss still remain unclear. Evidence exists that Toll-like receptor (TLR) signaling regulates both inflammation and bone metabolism and that the receptor activator of NF-κB ligand (RANKL) and its receptor RANK are the key regulators for bone remodeling and for the activation of osteoclasts. Here, we investigate the direct effects of the periodontal pathogen Porphyromonas gingivalis on osteoclast dif

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Thomson, W. Murray, Aubrey Sheiham, and A. John Spencer. "Sociobehavioral aspects of periodontal disease." Periodontology 2000 60, no. 1 (August 22, 2012): 54–63. http://dx.doi.org/10.1111/j.1600-0757.2011.00405.x.

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Taubman, M. A., E. D. Stoufi, G. J. Seymour, D. J. Smith, and J. L. Ebersole. "Immunoregulatory Aspects of Periodontal Disease." Advances in Dental Research 2, no. 2 (November 1988): 328–33. http://dx.doi.org/10.1177/08959374880020022201.

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This manuscript reviews our studies of the composition and functional capabilities of gingival tissue lymphocytes from patients with periodontal disease. The emphasis has been on phenotyping the local lymphoid infiltration in gingival and periodontal disease. The preparation and phenotypic analyses of cells recovered from diseased and healthy human periodontal tissues indicated that T-cell subset ratios from diseased tissue were significantly decreased compared with peripheral blood or normal tissue ratios. These reductions were verified in a second study we performed using two-color immunoflu

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Adamička, M., A. Adamičková, L. Danišovič, A. Gažová, and J. Kyselovič. "Pharmacological Approaches and Regeneration of Bone Defects with Dental Pulp Stem Cells." Stem Cells International 2021 (September 29, 2021): 1–7. http://dx.doi.org/10.1155/2021/4593322.

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Bone defects in the craniomaxillofacial skeleton vary from small periodontal defects to extensive bone loss, which are difficult to restore and can lead to extensive damage of the surrounding structures, deformities, and limited functions. Plenty of surgical regenerative procedures have been developed to reconstruct or prevent alveolar defects, based on guided bone regeneration involving the use of autogenous bone grafts or bone substituents. However, these techniques have limitations in the restoration of morphological and functional reconstruction, thus stopping disease progression but not r

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Evstropov, Vladimir, Galina Zelenkova, Sergei Tresnitskii, Anna Spirina, Pavel Bykadorov, Mikhael Yenin, Еkaterina Danileyko, and Alexey Ermakov. "Immunological aspects of inflammatory periodontal disease (analytical review)." E3S Web of Conferences 210 (2020): 06005. http://dx.doi.org/10.1051/e3sconf/202021006005.

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Clinical and immunological parallels in inflammatory periodontal diseases are considered taking into account some features of the functioning of general and local structures of the immune system in periodontitis of varying severity, chronic generalized periodontitis, aggressive periodontitis. In the analysis of immunopathogenesis of inflammatory periodontal diseases, an essential role is given to an imbalance in the immune and cytokine system.

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Velea, Oana A., Dan Onisei, Doina Onisei, Andreea Pogan, Corrado Paganelli, and Iulian P. Velea. "Microbiological Aspects In Periodontal Disease And Diabetes Mellitus." Romanian Journal of Diabetes Nutrition and Metabolic Diseases 21, no. 2 (June 1, 2014): 151–61. http://dx.doi.org/10.2478/rjdnmd-2014-0020.

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Abstract Background and Aims. Scientists are constantly showing a high interest for the relationship between Periodontal Disease (PD) and Diabetes Mellitus (DM). PD, “the sixth complication” of DM is recognized to be a chronic gram-negative anaerobic infectious disease. This paper is aimed at reviewing and evaluating the correlations between PD and DM from a microbiological point of view. Treatment implications of PD’s management as an important component of DM care is reviewed in the light of microbiological current knowledge. Materials and Methods. Microbiological studies and clinical trials

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Kinane, Denis F., and David F. Lappin. "Clinical, pathological and immunological aspects of periodontal disease." Acta Odontologica Scandinavica 59, no. 3 (January 2001): 154–60. http://dx.doi.org/10.1080/000163501750266747.

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Kajiya, Mikihito, and Hidemi Kurihara. "Molecular Mechanisms of Periodontal Disease." International Journal of Molecular Sciences 22, no. 2 (January 19, 2021): 930. http://dx.doi.org/10.3390/ijms22020930.

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Periodontal disease, one of the most prevalent human infectious diseases, is characterized by chronic inflammatory tissue destruction of the alveolar bone and the connective tissues supporting the tooth [...]

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Puri, Komal, Nikhil Puri, Vidya Dodwad, and Sujata Surendra Masamatti. "Restorative aspects of periodontal disease: an update part 1." Dental Update 41, no. 6 (July 2, 2014): 545–52. http://dx.doi.org/10.12968/denu.2014.41.6.545.

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Puri, Nikhil, Komal Puri, Sujata Surendra Masamatti, and Vidya Dodwad. "Restorative aspects of periodontal disease: an update part 2." Dental Update 41, no. 7 (September 2, 2014): 638–52. http://dx.doi.org/10.12968/denu.2014.41.7.638.

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Kang, Yoon H., and Francois Berthiaume. "Periodontitis: Clinical Aspects, Pathophysiology, Experimental Approaches and Emerging Therapies." Nano LIFE 11, no. 03 (July 16, 2021): 2130006. http://dx.doi.org/10.1142/s1793984421300065.

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This review paper presents an overview of periodontal disease, beginning with clinical aspects including prevalence, etiology, disease progression mechanisms and implications for general health, followed by current diagnostic and therapeutic approaches. We then describe experimental models used for in vitro and in vivo investigations of periodontal disease, and emerging therapeutic approaches based on biomedical and tissue engineering concepts, nanotechnology, gene and stem cell therapies. We aim to provide bioengineers, tissue engineers and nanotechnology researchers an overall understanding

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Degasperi, Giovanna R., Augusto Etchegaray, Larissa Marcelino, Ahron Sicard, Karina Villalpando, and Sérgio L. Pinheiro. "Periodontal Disease: General Aspects from Biofilm to the Immune Response Driven by Periodontal Pathogens." Advances in Microbiology 08, no. 01 (2018): 1–17. http://dx.doi.org/10.4236/aim.2018.81001.

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Bolstad, A. I., H. B. Jensen, and V. Bakken. "Taxonomy, biology, and periodontal aspects of Fusobacterium nucleatum." Clinical Microbiology Reviews 9, no. 1 (January 1996): 55–71. http://dx.doi.org/10.1128/cmr.9.1.55.

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The pathogenic potential of Fusobacterium nucleatum and its significance in the development of periodontal diseases, as well as in infections in other organs, have gained new interest for several reasons. First, this bacterium has the potential to be pathogenic because of its number and frequency in periodontal lesions, its production of tissue irritants, its synergism with other bacteria in mixed infections, and its ability to form aggregates with other suspected pathogens in periodontal disease and thus act as a bridge between early and late colonizers on the tooth surface. Second, of the mi

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Voinescu, I., D. Ferechide, CM Cristache, L. Burlibasa, and M. Burlibasa. "Ethical and legal aspects in periodontal disease diagnosis and therapy." Romanian Journal of Legal Medicine 27, no. 1 (March 1, 2019): 57–64. http://dx.doi.org/10.4323/rjlm.2019.57.

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Salmen, Teodor, Bianca Margareta Mihai, Ruxandra Andreea Iarca, Bianca Adriana Stan, Vlad Dima, and Roxana Elena Bohiltea. "Diabetes mellitus and periodontal disease." Romanian Journal of Stomatology 67, no. 4 (December 31, 2021): 244–46. http://dx.doi.org/10.37897/rjs.2021.4.8.

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Diabetes mellitus (DM) is a chronic non-transmittable disease and, alongside periodontal disease, another chronic disease, but with infectious and inflammatory etiology, that have increasing prevalence. The link between the two comorbidities is bidirectional, with common aspects such the inflammatory state, altered immune response and healing process. This link is alimented, also, by oxidative stress, an element that can initiate proinflammatory pathways in both pathologies. Moreover, periodontal disease favors the development of DM complications by a multifactorial mechanism centered on hyper

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Ulitovskiy, S. B., and E. S. Alexeeva. "Periodontal diseases: hygiene aspects of complex attitude in treatment." Medical alphabet 2, no. 11 (November 23, 2019): 22–26. http://dx.doi.org/10.33667/2078-5631-2019-2-11(386)-22-26.

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The anti-inflammatory efficacy was found to be 60.93 %, the blood-stopping efficacy was 60.84 % in the group of periodontal disease patients, which was due to the use of Acept’s oral hygiene in preventing the onset and development of inflammation in the periodontal.

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Emrizal, Reeki, and Nor Azlan Nor Muhammad. "Phylogenetic comparison between Type IX Secretion System (T9SS) protein components suggests evidence of horizontal gene transfer." PeerJ 8 (June 26, 2020): e9019. http://dx.doi.org/10.7717/peerj.9019.

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Porphyromonas gingivalis is one of the major bacteria that causes periodontitis. Chronic periodontitis is a severe form of periodontal disease that ultimately leads to tooth loss. Virulence factors that contribute to periodontitis are secreted by Type IX Secretion System (T9SS). There are aspects of T9SS protein components that have yet to be characterised. Thus, the aim of this study is to investigate the phylogenetic relationship between members of 20 T9SS component protein families. The Bayesian Inference (BI) trees for 19 T9SS protein components exhibit monophyletic clades for all major cl

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Marinho, Ricardo Romulo Batista, João Thiago Beltrão Nunes Damasceno, and Rômulo Savage Vanderlan do Nascimento. "Aspecto etiológico, imunológico e patogênico da doença periodontal / Etiological, immunological and pathogenic aspects of periodontal disease." Brazilian Journal of Health Review 5, no. 3 (May 30, 2022): 10494–504. http://dx.doi.org/10.34119/bjhrv5n3-213.

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MIGLIARI, Dante A., Norberto N. SUGAYA, Maria A. MIMURA, and Luiz Carlos CUCÉ. "Periodontal aspects of the juvenile form of paracoccidioidomycosis." Revista do Instituto de Medicina Tropical de São Paulo 40, no. 1 (January 1998): 15–18. http://dx.doi.org/10.1590/s0036-46651998000100004.

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Three cases of the juvenile form of paracoccidioidomycosis are reported. Emphasis has been given to the oral manifestations, particularly the periodontal involvement. The main periodontal findings were: generalized and progressive alveolar bone destruction leading to gingival recession with exposure of the tooth roots, and spontaneous tooth losses. The gingival mucosa was predominantly smooth, erithematous and slightly swollen. These aspects, although rare, may be the earliest signs of the disease and sometimes its only manifestation.

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Horne, Poppy E., Lyndie A. Foster Page, Jonathan W. Leichter, Ellie T. Knight, and W. Murray Thomson. "Psychosocial aspects of periodontal disease diagnosis and treatment: A qualitative study." Journal of Clinical Periodontology 47, no. 8 (June 22, 2020): 941–51. http://dx.doi.org/10.1111/jcpe.13309.

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Islam, AKMM, MM Rahman, M. Ullah, and L. Yeasmin. "Link between Periodontal Disease and Coronary Artery Disease: Bangladesh Perspective." Cardiovascular Journal 7, no. 1 (November 2, 2014): 44–54. http://dx.doi.org/10.3329/cardio.v7i1.20800.

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Coronary artery disease (CAD) is an increasingly important medical and public healthproblem, and is the leading cause of mortality in Bangladesh. Besides conventional risk factors and ethnicity, a number of emerging risk factors may explain the undue prevalence of CAD in this population. Periodontal disease (PD) is one of them, with prevalence of approximately 50%. As with many other diseases, PD is associated with CAD, and the association is independent of conventional risk factors. Low socioeconomic condition, illiteracy and ignorance, metabolic syndrome, nutritional deficiencies including h

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Oz, Helieh S., and David A. Puleo. "Animal Models for Periodontal Disease." Journal of Biomedicine and Biotechnology 2011 (2011): 1–8. http://dx.doi.org/10.1155/2011/754857.

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Animal models and cell cultures have contributed new knowledge in biological sciences, including periodontology. Although cultured cells can be used to study physiological processes that occur during the pathogenesis of periodontitis, the complex host response fundamentally responsible for this disease cannot be reproducedin vitro. Among the animal kingdom, rodents, rabbits, pigs, dogs, and nonhuman primates have been used to model human periodontitis, each with advantages and disadvantages. Periodontitis commonly has been induced by placing a bacterial plaque retentive ligature in the gingiva

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Saveleva, N. N., I. I. Sokolova, S. I. German, and T. V. Tomilina. "SOME ASPECTS OF THE EATIOLOGY OF PARODONTUS DISEASES. (LITERATURE REVIEW)." Ukrainian Dental Almanac, no. 2 (June 25, 2018): 54–59. http://dx.doi.org/10.31718/2409-0255.2.2018.13.

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The review of the scientific literature is devoted to the topical issues of studying the etiology of periodontal diseases, which are one of the most common and complex pathologies of the maxillofacial region. Analysis of recent studies proves a stable relationship between the development of periodontal diseases and disorders in the immune system, the neurohumoral system, metabolic disorders, genetic predisposition, and so on. The article presents the data obtained in the course of studying the literature on the role of disorders in the functioning of individual organs (gastrointestinal t

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Matos, Jefferson, Alessandra Dossi Pinto, Kalenna Soriano Lage, Pedro Jacy Santos Diamantino, Guilherme Da Rocha Scalzer Lopes, and Valdir Cabral Andrade. "Interrelation between Diabetes Mellitus and periodontal disease: an integrative review." Journal of Dentistry & Public Health 9, no. 3 (September 17, 2018): 238–47. http://dx.doi.org/10.17267/2596-3368dentistry.v9i3.2006.

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Introduction: In cases where there is an association of two or more diseases, it’s complex to improve individual’s well-being and quality of life, especially when these diseases have a bidirectional relation, as observed between diabetes mellitus and periodontal disease. Aim: The present study aims to review the literature on the relation between Diabetes Mellitus and Periodontal Disease, identifying the main aspects and pathognomonic characteristics.Conclusion:Due to the exposed in the literature on the interrelation of diabetes mellitus and periodontal disease, further studies are needed for

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Sordi, Mariane Beatriz, Ricardo de Souza Magini, Layla Panahipour, and Reinhard Gruber. "Pyroptosis-Mediated Periodontal Disease." International Journal of Molecular Sciences 23, no. 1 (December 29, 2021): 372. http://dx.doi.org/10.3390/ijms23010372.

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Pyroptosis is a caspase-dependent process relevant to the understanding of beneficial host responses and medical conditions for which inflammation is central to the pathophysiology of the disease. Pyroptosis has been recently suggested as one of the pathways of exacerbated inflammation of periodontal tissues. Hence, this focused review aims to discuss pyroptosis as a pathological mechanism in the cause of periodontitis. The included articles presented similarities regarding methods, type of cells applied, and cell stimulation, as the outcomes also point to the same direction considering the ce

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Puzin, S. N., I. V. Pryanikov, N. B. Vanchenko, K. G. Karakov, and M. A. Shurgaya. "MEDICAL AND SOCIAL ASPECTS OF CHRONIC GENERAL PARODONTITIS." Medical and Social Expert Evaluation and Rehabilitation 21, no. 3-4 (December 15, 2018): 129–33. http://dx.doi.org/10.18821/1560-9537-2018-21-3-4-129-133.

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A healthy smile is one of the main components of a person’s attractiveness, which makes it possible to improve the quality of communication with others in a personal and social aspect. Dental health depends on the state of the periodontal complex. The vast majority of people of different ages suffer from periodontal disease and seek dental care. The significant prevalence, the adverse effect of foci of periodontal infection on the body, the large loss of teeth cause both medical and social significance of this problem. In this regard, the tasks for the treatment of inflammatory diseases of per

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Hefti, Arthur F. "Periodontal Probing." Critical Reviews in Oral Biology & Medicine 8, no. 3 (July 1997): 336–56. http://dx.doi.org/10.1177/10454411970080030601.

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For decades, probing clinical pocket depth and attachment level have been recognized as the dentist's most important tools in diagnosing periodontal health and disease. They are physical methods to measure the distance from the bottom of a pocket to a reference line, usually the gingival margin or the cemento-enamel junction. Probing accuracy and precision are affected by factors like the design of the probe, probing force, probe position, pocket depth, or tissue inflammation. Recently, several new electronic periodontal probes have been developed. They feature high instrument precision, allow

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Sobocki, Bartosz Kamil, Charbel A. Basset, Bożena Bruhn-Olszewska, Paweł Olszewski, Olga Szot, Karolina Kaźmierczak-Siedlecka, Mateusz Guziak, Luigi Nibali, and Angelo Leone. "Molecular Mechanisms Leading from Periodontal Disease to Cancer." International Journal of Molecular Sciences 23, no. 2 (January 16, 2022): 970. http://dx.doi.org/10.3390/ijms23020970.

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Periodontitis is prevalent in half of the adult population and raises critical health concerns as it has been recently associated with an increased risk of cancer. While information about the topic remains somewhat scarce, a deeper understanding of the underlying mechanistic pathways promoting neoplasia in periodontitis patients is of fundamental importance. This manuscript presents the literature as well as a panel of tables and figures on the molecular mechanisms of Porphyromonas gingivalis and Fusobacterium nucleatum, two main oral pathogens in periodontitis pathology, involved in instigati

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Roudebush, Philip, Ellen Logan, and Fraser A. Hale. "Evidence-Based Veterinary Dentistry: A Systematic Review of Homecare for Prevention of Periodontal Disease in Dogs and Cats." Journal of Veterinary Dentistry 22, no. 1 (March 2005): 6–15. http://dx.doi.org/10.1177/089875640502200101.

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Successful treatment and prevention of periodontal disease in pet animals requires a multidimensional approach to identify and eliminate exacerbating factors, provide scheduled professional examinations and care, and plan and implement a dental homecare program. Over the years, many therapeutic and preventive interventions have been developed or advocated for periodontal disease, but evidence of efficacy or effectiveness is highly variable. Accordingly, the main objective of this systematic review is to identify and critically appraise the evidence supporting various aspects of homecare for pr

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