Bibliografias temáticas / Pulmonary surfactant

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Literatura científica selecionada sobre o tema "Pulmonary surfactant"

Autor: Grafiati
Publicado: 4 de junho de 2021
Última modificação: 25 de julho de 2025

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Artigos de revistas sobre o assunto "Pulmonary surfactant"

1

van Golde, LMG, JJ Batenburg, and B. Robertson. "The Pulmonary Surfactant System." Physiology 9, no. 1 (1994): 13–20. http://dx.doi.org/10.1152/physiologyonline.1994.9.1.13.

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The pulmonary surfactant system includes specific proteins involved in the regulation of surfactant secretion and recycling, conversion of secreted lamellar bodies to tubular myelin, film adsorption, and stimulation of alveolar macrophages. Hydrophobic proteins are essential for the rapid physiological action of exogenous surfactants currently used in clinical practice.
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2

Ramanathan, Rangasamy. "Surfactants in the Management of Respiratory Distress Syndrome in Extremely Premature Infants." Journal of Pediatric Pharmacology and Therapeutics 11, no. 3 (2006): 132–44. http://dx.doi.org/10.5863/1551-6776-11.3.132.

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Respiratory distress syndrome (RDS) is primarily due to decreased production of pulmonary surfactant, and it is associated with significant neonatal morbidity and mortality. Exogenous pulmonary surfactant therapy is currently the treatment of choice for RDS, as it demonstrates the best clinical and economic outcomes. Studies confirm the benefits of surfactant therapy to include reductions in mortality, pneumothorax, and pulmonary interstitial emphysema, as well as improvements in oxygenation and an increased rate of survival without bronchopulmonary dysplasia. Phospholipids (PL) and surfactant
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Dipak, Kumar Dhar, and Paul Debasish. "Surfactant Replacement Therapy: An Overview." International Journal of Science and Healthcare Research 5, no. 2 (2020): 399–406. https://doi.org/10.5281/zenodo.3931623.

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Pulmonary surfactant is a soap-like chemical synthesized by type II alveolar pneumocytes and is a mixture of phospholipids (predominantly dipalmitoylphosphatidylcholine), some other lipids and proteins. Its main functions include lowering the surface tension and maintaining the stability of alveoli. The first documented trial involving exogenous use of surfactants as a therapy was recorded in early 1970s using synthetically produced phospholipid mixtures once the chemical composition of surfactants was deciphered. Gradually there was a transition to the use of more natural sources. And animal
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Satyam Prakash, Hem Shankar Yadav, and Om Prakash Yadav. "Pulmonary Surfactant in Health and Disease: An Overview." Janaki Medical College Journal of Medical Science 12, no. 03 (2024): 108–22. https://doi.org/10.3126/jmcjms.v12i03.73990.

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Surfactant is a complex mixture of phospholipids, mainly dipalmitoylphosphatidylcholine (DPCC) and surfactant proteins (SP); SP-A, SP-B, SP-C, and SP-D. DPCC plays a crucial role in lowering the surface tension, while SPs provide immunity against invading pathogens. SPs also enhance the activity of phospholipids, aiding in the adsorption and spread of surfactants all over the alveolar surface. Surfactant production starts as early as 24 weeks of gestation in humans and peaks at about 36-38 weeks. The generation and secretion of lung surfactants are tightly regulated processes. Surfactant is sy
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5

Ignatova, G. L., V. N. Antonov, and I. A. Zakharova. "The use of exogenous surfactant in pulmonological practice." Meditsinskiy sovet = Medical Council, no. 5 (May 9, 2024): 41–48. http://dx.doi.org/10.21518/ms2024-089.

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A lung surfactant is a complex mixture of lipids and proteins necessary to maintain proper lung function. Drug changes play an important role in chronic lung diseases such as chronic obstructive pulmonary disease, bronchial asthma and idiopathic pulmonary fibrosis. The purpose of this article is to substantiate the use of exogenous surfactant in various respiratory diseases, based on the analysis of publications in domestic and international medical journals, as well as their own experience of application in real clinical practice. This review primarily discusses the contribution of pulmonary
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Bernhard, Wolfgang, Andreas Gebert, Gertrud Vieten, et al. "Pulmonary surfactant in birds: coping with surface tension in a tubular lung." American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 281, no. 1 (2001): R327—R337. http://dx.doi.org/10.1152/ajpregu.2001.281.1.r327.

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As birds have tubular lungs that do not contain alveoli, avian surfactant predominantly functions to maintain airflow in tubes rather than to prevent alveolar collapse. Consequently, we have evaluated structural, biochemical, and functional parameters of avian surfactant as a model for airway surfactant in the mammalian lung. Surfactant was isolated from duck, chicken, and pig lung lavage fluid by differential centrifugation. Electron microscopy revealed a uniform surfactant layer within the air capillaries of the bird lungs, and there was no tubular myelin in purified avian surfactants. Phosp
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Suresh, G. K., and R. F. Soll. "Exogenous Surfactant Therapy in Newborn Infants." Annals of the Academy of Medicine, Singapore 32, no. 3 (2003): 335–45. http://dx.doi.org/10.47102/annals-acadmedsg.v32n3p335.

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Exogenous surfactant therapy has an established role in the management of neonatal respiratory distress syndrome (RDS). This article summarises the current evidence on surfactant therapy. The use of surfactant for the treatment or prophylaxis of neonatal RDS results in a 30% to 65% relative reduction in the risk of pneumothorax and up to a 40% relative reduction in the risk of mortality. Adverse effects, of which pulmonary haemorrhage is of most concern, are infrequent and long-term follow-up studies of treated patients are reassuring. Natural surfactants have advantages over synthetic surfact
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PUTMAN, Esther, Lambert A. J. M. CREUWELS, Lambert M. G. van GOLDE, and Henk P. HAAGSMAN. "Surface properties, morphology and protein composition of pulmonary surfactant subtypes." Biochemical Journal 320, no. 2 (1996): 599–605. http://dx.doi.org/10.1042/bj3200599.

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Separation of surfactant subtypes is now commonly used as a parameter in assessing the amount of active compared with inactive material in various models of lung injury. The protein content, morphology and surface activity were determined of the heavy and light subtype isolated by differential centrifugation. Here we report the presence of surfactant proteins B and C in the heavy subtype but not in the light subtype. Adsorption studies revealed that separation of fast adsorbing bronchoalveolar lavage resulted in slowly adsorbing heavy and light subtypes. Surfactant, reconstituted from heavy an
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Dushianthan, Ahilanandan, Michael P. W. Grocott, Ganapathy Senthil Murugan, Tom M. A. Wilkinson, and Anthony D. Postle. "Pulmonary Surfactant in Adult ARDS: Current Perspectives and Future Directions." Diagnostics 13, no. 18 (2023): 2964. http://dx.doi.org/10.3390/diagnostics13182964.

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Acute respiratory distress syndrome (ARDS) is a major cause of hypoxemic respiratory failure in adults, leading to the requirement for mechanical ventilation and poorer outcomes. Dysregulated surfactant metabolism and function are characteristic of ARDS. A combination of alveolar epithelial damage leading to altered surfactant synthesis, secretion, and breakdown with increased functional inhibition from overt alveolar inflammation contributes to the clinical features of poor alveolar compliance and alveolar collapse. Quantitative and qualitative alterations in the bronchoalveolar lavage and tr
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Nguyen, Thuy N., Stephanie M. Cunsolo, Peter Gal, and J. Laurence Ransom. "Infasurf and Curosurf: Theoretical and Practical Considerations with New Surfactants." Journal of Pediatric Pharmacology and Therapeutics 8, no. 2 (2003): 97–114. http://dx.doi.org/10.5863/1551-6776-8.2.97.

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Type II pneumocytes, normally responsible for surfactant production and release, are insufficiently formed and differentiated in the premature infant born before 34 weeks' gestation. Without an adequate amount of pulmonary surfactant, alveolar surface tension increases, leading to collapse and decreased lung compliance. Pulmonary surfactants are naturally occurring substances made of lipids and proteins. They lower surface tension at the interface between the air in the lungs, specifically at the alveoli, and the blood in the capillaries. This review examines the relative benefits of the two m
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Teses / dissertações sobre o assunto "Pulmonary surfactant"

1

Lewis, R. W. "Pulmonary surfactant metabolism." Thesis, Cardiff University, 1985. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.332108.

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2

Hockey, Peter Morey. "Pulmonary surfactant and asthma." Thesis, University of Southampton, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.274434.

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3

Nilsson, Kristina. "Solute exchange across the alveolo-capillary barrier." Lund : Depts. of Clinical Physiology, Malmö University Hospital and Lund University Hospital, Lund University, 1997. http://books.google.com/books?id=A0hrAAAAMAAJ.

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Mo, Young Keun. "Surfactant proteins in extra pulmonary sites /." [St. Lucia, Qld.], 2005. http://www.library.uq.edu.au/pdfserve.php?image=thesisabs/absthe19083.pdf.

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5

Sullivan, Lucy Catherine. "The molecular evolution of vertebrate pulmonary surfactant /." Title page, summary and introduction only, 1996. http://web4.library.adelaide.edu.au/theses/09SB/09sbs949.pdf.

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6

Worthman, Lynn-Ann D. "Surfactant protein A (SP-A) affects pulmonary surfactant morphology and biophysical properties." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1997. http://www.collectionscanada.ca/obj/s4/f2/dsk2/tape16/PQDD_0014/MQ34241.pdf.

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Wood, Philip. "Control of pulmonary surfactant secretion : an evolutionary perspective /." Title page, table of contents and abstract only, 1999. http://web4.library.adelaide.edu.au/theses/09PH/09phw878.pdf.

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Mander, Ann. "Pulmonary surfactant and neutrophil function in cystic fibrosis." Thesis, University of Southampton, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.310701.

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McCarty, Kenneth Dean. "Characterization of pulmonary surfactant apoproteins in the diabetic mouse." CSUSB ScholarWorks, 1989. https://scholarworks.lib.csusb.edu/etd-project/512.

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Espinosa, Frank F. (Frank Francis). "Exogenous surfactant transport through the pulmonary airways : improving surfactant replacement therapy for neonatal respiratory distress syndrome." Thesis, Massachusetts Institute of Technology, 1996. http://hdl.handle.net/1721.1/10974.

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Livros sobre o assunto "Pulmonary surfactant"

1

Rooney, Seamus A. Lung surfactant: Cellular and molecular processing. Landes Bioscience, 1998.

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2

Kaushik, Nag, ed. Lung surfactant function and disorder. Taylor & Francis, 2005.

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3

1952-, Müller B., Wichert P. von, and International Symposium on Lung Surfactant (4th : 1992 : Marburg, Germany), eds. Lung surfactant: Basic research in the pathogenesis of lung disorders. Karger, 1994.

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4

R, Bourbon Jacques, ed. Pulmonary surfactant: Biochemical, functional, regulatory, and clinical concepts. CRC Press, 1991.

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5

1935-, Robertson Bengt, Golde, Lambert M. G. van, 1940-, and Batenburg J. J, eds. Pulmonary surfactant: From molecular biology to clinical practice. Elsevier, 1992.

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6

Laboratories, Ross, ed. Surfactant treatment of lung diseases: Report of the 96th Ross Conference on Pediatric Research. Ross Laboratories, 1988.

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7

G, Bevilacqua, Parmigiani Stefano, and Robertson Bengt 1935-, eds. Surfactant in clinical practice: Proceedings of an international symposium, Parma, June 4-5, 1990. Harwood Academic Publishers, 1993.

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8

Devidas, Menon, and Canadian Coordinating Office for Health Technology Assessment., eds. Exosurf Neonatal for surfactant replacement therapy. Canadian Coordinating Office for Health Technology Assessment, 1991.

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9

International Symposium on Surfactant Replacement Therapy (1987 Rotterdam, Netherlands). Surfactant replacement therapy in neonatal and adult respiratory distress syndrome. Springer-Verlag, 1988.

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10

R, Wauer R., ed. Respiratory distress syndrome of premature infants: Significance of surfactant and its pharmacological influence : pre-congress workshop of the 10th European Congress of Perinatal Medicine, Leipzig, GDR, August 12, 1986. Volk und Gesundheit, 1987.

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Capítulos de livros sobre o assunto "Pulmonary surfactant"

1

Alemanno, Fernando. "Pulmonary Surfactant." In Biochemistry for Anesthesiologists and Intensivists. Springer International Publishing, 2019. http://dx.doi.org/10.1007/978-3-030-26721-6_10.

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2

Enhorning, G. "Evaluation of Pulmonary Surfactant." In Surfactant Replacement Therapy. Springer Berlin Heidelberg, 1988. http://dx.doi.org/10.1007/978-3-642-73305-5_2.

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3

Harwood, John L., Llinos W. Morgan, and Tanya Greatrex. "Alveolar Surfactant." In Pulmonary Biology in Health and Disease. Springer New York, 2002. http://dx.doi.org/10.1007/978-0-387-22435-0_3.

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4

Robertson, B., and S. Schürch. "Assessment of surfactant function." In Methods in Pulmonary Research. Birkhäuser Basel, 1998. http://dx.doi.org/10.1007/978-3-0348-8855-4_14.

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Enhorning, G. "Pulmonary Surfactant: Evolution of Functional Concepts." In Surfactant Replacement Therapy. Springer Berlin Heidelberg, 1988. http://dx.doi.org/10.1007/978-3-642-73305-5_1.

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6

Willson, Douglas F., Patricia R. Chess, Zhengdong Wang, and Robert H. Notter. "Pulmonary Surfactant: Biology and Therapy." In The Respiratory Tract in Pediatric Critical Illness and Injury. Springer London, 2008. http://dx.doi.org/10.1007/978-1-84800-925-7_10.

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7

Armbruster, S., J. Klein, E. M. Stouten, W. Erdmann, and B. Lachmann. "Surfactant in Pulmonary Oxygen Toxicity." In Oxygen Transport to Tissue IX. Springer US, 1987. http://dx.doi.org/10.1007/978-1-4684-7433-6_40.

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Lachmann, B. "In Vivo Tests for Evaluation of Pulmonary Surfactant." In Surfactant Replacement Therapy. Springer Berlin Heidelberg, 1988. http://dx.doi.org/10.1007/978-3-642-73305-5_4.

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9

Calkovska, Andrea, and Egbert Herting. "Exogenous Surfactant in Respiratory Distress Syndrome." In Applied Technologies in Pulmonary Medicine. KARGER, 2010. http://dx.doi.org/10.1159/000322778.

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Pison, Ulrich, and Sylvia Pietschmann. "Host Defense Capacities of Pulmonary Surfactant." In Acute Respiratory Distress Syndrome. Springer US, 1998. http://dx.doi.org/10.1007/978-1-4419-8634-4_11.

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Trabalhos de conferências sobre o assunto "Pulmonary surfactant"

1

Gaver, Donald P., Melissa A. Krueger, and Samir N. Ghadiali. "The Influence of Surfactant Physicochemical Properties on Pulmonary Interfacial Flow Analogues." In ASME 1997 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 1997. http://dx.doi.org/10.1115/imece1997-0218.

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Abstract Many of the lung’s mechanical properties are influenced by pulmonary surfactant physicochemical characteristics. Pulmonary surfactant is a complex lipid-protein mixture formed in the type II alveolar cells and secreted into the alveolar subphase [1]. These substances reduce the surface tension at the air-liquid interface of the lining fluid that coats the interior of the lung. At sufficiently high concentrations, pulmonary surfactant reduces the surface tension to near zero and. in the process, stabilizes the alveoli and small airways [2–4].
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2

Siebert, Trina A., and Sandra Rugonyi. "Surfactant Spreading on a Thin Film Is Sensitive to Film Thickness: Implications for In Vivo Pulmonary Systems Versus In Vitro Scenarios." In ASME 2007 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2007. http://dx.doi.org/10.1115/sbc2007-174065.

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The role of pulmonary surfactant is critical to the mechanics of the lung. Pulmonary surfactant forms a monolayer film at the air-liquid interface of a thin film of fluid lining the alveoli. Without surfactant, the air-liquid surface tension would be too high and the lungs would collapse during exhalation, as is the case with premature babies who develop respiratory distress syndrome (RDS) because they lack a sufficient amount of pulmonary surfactant [1]. Because an increase in surfactant surface concentration correlates with a decrease in surface tension, the surface tension gradients resulti
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3

Kolmogorov, I. M., V. A. Timoshenko, I. V. Grigoryan, and I. M. Le-Deygen. "INTERACTION OF LIPOSOMAL FORMS OF LEVOFLOXACIN WITH PULMONARY SURFACTANT." In XI МЕЖДУНАРОДНАЯ КОНФЕРЕНЦИЯ МОЛОДЫХ УЧЕНЫХ: БИОИНФОРМАТИКОВ, БИОТЕХНОЛОГОВ, БИОФИЗИКОВ, ВИРУСОЛОГОВ, МОЛЕКУЛЯРНЫХ БИОЛОГОВ И СПЕЦИАЛИСТОВ ФУНДАМЕНТАЛЬНОЙ МЕДИЦИНЫ. IPC NSU, 2024. https://doi.org/10.25205/978-5-4437-1691-6-77.

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The interaction between liposomal levofloxacin and bovine pulmonary surfactant was investigated. It has been demonstrated using Langmuir-Wilhelmy techniques, AFM, IR and fluorescence microscopy that functionalizing the surface of liposomes with mannosylated chitosan minimizes the initial fusion of vesicles with surfactant, while also assisting in the retention of the formulation at the surfactant-air interface.
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Numata-Nakamura, M., H. Lee, H. W. Chu, M. A. Seibold, and D. R. Voelker. "Pulmonary Surfactant Lipids Antagonize Human Rhinovirus Infections." In American Thoracic Society 2019 International Conference, May 17-22, 2019 - Dallas, TX. American Thoracic Society, 2019. http://dx.doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a5757.

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Meissner, Sven, Stefan Adami, Lilla Knels, Xiangyu Hu, Nikolaus Adams, and Edmund Koch. "Experimental And Numerical Studies On Pulmonary Surfactant." In American Thoracic Society 2010 International Conference, May 14-19, 2010 • New Orleans. American Thoracic Society, 2010. http://dx.doi.org/10.1164/ajrccm-conference.2010.181.1_meetingabstracts.a3021.

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Briva, Arturo, Leonel Malacrida, Horacio Botti, et al. "Halogenated Anesthetics Impairs Biophysical Properties Of Pulmonary Surfactant." In American Thoracic Society 2011 International Conference, May 13-18, 2011 • Denver Colorado. American Thoracic Society, 2011. http://dx.doi.org/10.1164/ajrccm-conference.2011.183.1_meetingabstracts.a5241.

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Arciniegas Flores, R. A., I. A. Vital, K. Medepalli, D. DeMarzo, M. K. Glassberg Csete, and R. A. Alvarez. "Pulmonary Fibrosis Due to a Novel Surfactant Protein Mutation." In American Thoracic Society 2019 International Conference, May 17-22, 2019 - Dallas, TX. American Thoracic Society, 2019. http://dx.doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a5437.

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Suman, A., N. Sinha, H. Kaura, H. Rawal, and A. G. Espinoza. "Drowning in Surfactant - A Case of Pulmonary Alveolar Proteinosis." In American Thoracic Society 2020 International Conference, May 15-20, 2020 - Philadelphia, PA. American Thoracic Society, 2020. http://dx.doi.org/10.1164/ajrccm-conference.2020.201.1_meetingabstracts.a1478.

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Hall, Stephen B., Ryan W. Loney, and Shankar B. Rananavare. "Mechanisms Of The Late Accelerated Adsorption Of Pulmonary Surfactant." In American Thoracic Society 2011 International Conference, May 13-18, 2011 • Denver Colorado. American Thoracic Society, 2011. http://dx.doi.org/10.1164/ajrccm-conference.2011.183.1_meetingabstracts.a5243.

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Furuhashi, K., S. Sakurai, H. Yasui, et al. "Surfactant Protein D in Patients with Chronic Pulmonary Aspergillosis." In American Thoracic Society 2019 International Conference, May 17-22, 2019 - Dallas, TX. American Thoracic Society, 2019. http://dx.doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a3694.

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Relatórios de organizações sobre o assunto "Pulmonary surfactant"

1

Cochrane, Charles G. Clinical Studies of Synthetic Peptide-Containing Pulmonary Surfactant in Patients with Adult Respiratory Distress Syndrome. Defense Technical Information Center, 1995. http://dx.doi.org/10.21236/ada302217.

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2

Rodríguez, Antonio Cruz, Begoña García Álvarez, and Bárbara Olmeda Lozano. El surfactante pulmonar, un sistema lipoproteico clave para la mecánica respiratoria. Sociedad Española de Bioquímica y Biología Molecular, 2023. http://dx.doi.org/10.18567/sebbmrev_215.202303.dc004.

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