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Artigos de revistas sobre o tema "Right to Genetic Identity"

Autor: Grafiati

Publicado: 4 de junho de 2021

Última modificação: 4 de fevereiro de 2022

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1

Sabatello, Maya. "The Politics of the Child's Right to Identity in a Disability-Free Society." International Journal of Children's Rights 17, no. 2 (2009): 177–206. http://dx.doi.org/10.1163/157181808x312131.

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AbstractThe essay examines the legal and moral implications of pre-natal genetic selection of disability in the context of children. I build on scholarly literature on the politics of identity and of culture to explore whether scientific developments prompt a child's "right to a sound mind and body." I consider this question in light of international human rights standards, including the recent European Conventions on Human Rights and Biomedicine, and particularly, the child's right to identity. I propose a new dual model to evaluate such biomedical decisions from a child-centred approach. Wha

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Monducci, Juri. "The protection of genetic information." SALUTE E SOCIETÀ, no. 3 (November 2010): 91–113. http://dx.doi.org/10.3280/ses2010-003007-ing.

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The law pertaining to personal data has developed in Italy over a thirty-year span that took us from recognition of such data in the case law, in 1975, to its statutory protection, in 2003. This evolution would subsequently come to the point of specifically regulating the processing of genetic data as data revealing an individual's genetic makeup, thereby also revealing the biological future of individuals and their offspring: this information describes an individual at a core level where the deepest, most unchangeable traits are found and can therefore nurture what is nowadays referred to as

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Mulligan, Andrea. "Protecting Identity In Collaborative Assisted Reproduction: The Right To Know One’s Gestational Surrogate." International Journal of Law, Policy and the Family 34, no. 1 (2020): 20–42. http://dx.doi.org/10.1093/lawfam/ebz017.

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Abstract Gestational surrogacy presents a unique form of parenthood: that which is biological but not genetic. This new form of parenthood demands a re-examination of the rights and duties that arise from the parent–child relationship. This article is concerned with the surrogate-born person’s right to know his or her gestational surrogate, an aspect of the right to identity. The springboard for this analysis is draft legislation in Ireland that proposes the creation of a legal right to trace one’s gestational surrogate. The purpose of this article is to interrogate the normative underpinnings

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Burmeister, Stefan. "Does the concept of genetic ancestry reinforce racism?" TATuP - Zeitschrift für Technikfolgenabschätzung in Theorie und Praxis 30, no. 2 (2021): 41–46. http://dx.doi.org/10.14512/tatup.30.2.41.

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Genetic ancestry is seen as an alternative to the problematic concept of race and is positioned against abusive racist and nationalist perspectives. The concept of genetic ancestry is nevertheless not free of racial categorizations. Increasingly, it is becoming an integral part of identity politics. Genetic ancestry is promoted as a way to give identity and visibility to marginalized groups but is also rejected as a form of biocolonialism. In xenophobic and racist discourses of right-wing groups, the concept has found fertile ground. The field of genetics is partly to blame for this since it o

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Montanari Vergallo, Gianluca, Enrico Marinelli, Natale Mario di Luca, and Simona Zaami. "Gamete Donation: Are Children Entitled to Know Their Genetic Origins? A Comparison of Opposing Views. The Italian State of Affairs." European Journal of Health Law 25, no. 3 (2018): 322–37. http://dx.doi.org/10.1163/15718093-12530378.

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Abstract Medically assisted fertilization techniques give rise to a wide array of issues, such as the rights to secrecy, partial anonymity or to the full disclosure of information about the donors’ identities. The authors espouse the right of donor-conceived children to know their biological origins, and delve into opposing views, either in favour of the gamete donors’ right to anonymity or against it. Be that as it may, the right to know one’s biological origins has been gaining a foothold as part of the broader right to personal identity. The latter is in fact codified and upheld in numerous

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Ravelingien, An, and Guido Pennings. "The Right to Know Your Genetic Parents: From Open-Identity Gamete Donation to Routine Paternity Testing." American Journal of Bioethics 13, no. 5 (2013): 33–41. http://dx.doi.org/10.1080/15265161.2013.776128.

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Cohen, I. Glenn. "Of Modest Proposals and Non-Identity: A Comment on the Right to Know Your Genetic Parents." American Journal of Bioethics 13, no. 5 (2013): 45–47. http://dx.doi.org/10.1080/15265161.2013.776132.

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Bliss, Catherine. "The Marketization of Identity Politics." Sociology 47, no. 5 (2013): 1011–25. http://dx.doi.org/10.1177/0038038513495604.

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Sociology has begun to question how new genetic sciences affect older ways of constructing and contesting social identity, including forms of identity politics that have brought women and minorities significant gains. This article presents US debates on genetics, identity politics, and race in order to theorize emergent transformations in light of the genomic revolution. Examining recent developments in the realms of pharmaceuticals and ancestry estimation, I argue that traditional forms of identity politics are still actively at work, though they are being marketized in novel ways. This artic

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Brenciani, Andrea, Erika Tiberi, Eleonora Morici, Erman Oryaşın, Eleonora Giovanetti, and Pietro E. Varaldo. "ICESp1116, the Genetic Element Responsible forerm(B)-Mediated, Inducible Resistance to Erythromycin in Streptococcus pyogenes." Antimicrobial Agents and Chemotherapy 56, no. 12 (2012): 6425–29. http://dx.doi.org/10.1128/aac.01494-12.

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ABSTRACTICESp1116, responsible forerm(B)-mediated, inducible erythromycin resistance inStreptococcus pyogenes, was comprehensively characterized, and its chromosomal integration site was determined. It displayed a unique mosaic organization consisting of a scaffold, related to TnGallo1 fromStreptococcus gallolyticus, with two inserted fragments separated by IS1216. One fragment, containingerm(B), displayed high-level identity to a portion of theS. pyogenesplasmid pSM19035; the other, containing a truncatedtet(M) gene, displayed high-level identity to the right-hand portion ofClostridium diffic

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Montanari Vergallo, Gianluca, and Natale Mario Di Luca. "La spinta verso una legislazione europea comune sul diritto di conoscere le proprie origini genetiche / The push towards common European legislation with respect to the right to know one’s genetic origins." Medicina e Morale 66, no. 6 (2018): 747–61. http://dx.doi.org/10.4081/mem.2017.518.

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A venti anni dalla sua approvazione, la Convenzione di Oviedo necessita di un aggiornamento. Infatti, non affronta la questione del diritto dei bambini nati da fecondazione eterologa di conoscere l’identità dei donatori di gameti. La Corte europea dei diritti dell’uomo ha recentemente stabilito che: a) il diritto di conoscere le proprie origini biologiche è tutelato dall’art. 8 della Convenzione dei diritti dell’uomo; b) tale diritto deve essere bilanciato con quello della madre biologica di rimanere anonima (c.d. parto anonimo). Al fine di trovare tale bilanciamento, una possibile soluzione c

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Turkmendag, Ilke. "It Is Just a “Battery”." Science, Technology, & Human Values 43, no. 1 (2017): 56–85. http://dx.doi.org/10.1177/0162243917722843.

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This article addresses the child’s right to know their genetic origins in mitochondrial donation. It focuses on the UK’s public debate on mitochondrial replacement techniques and examines the claims-making activities that shaped the donor information regulations. During the public consultation, downplaying the significance of the mitochondria helped distinguish mitochondria donors from gamete donors and determine their relational status with the resulting child. As a result, according to the Mitochondrial Donation regulations, mitochondria donors, unlike gamete donors, will not be required to

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Adhikari, Kamalesh, Edwin Bikundo, Xan Chacko, et al. "What Should Farmers’ Rights Look Like? The Possible Substance of a Right." Agronomy 11, no. 2 (2021): 367. http://dx.doi.org/10.3390/agronomy11020367.

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Farmers’ Rights formally appeared in the International Treaty on Plant Genetic Resources for Food and Agriculture (ITPGRFA) as a means of recognising the past, present, and future contributions of farmers in conserving, improving, and making available the plant genetic materials that are important for food and agriculture. Discussions have been underway under the auspices of the ITPGRFA’s Governing Body with the recent Ad Hoc Technical Expert Group on Farmers’ Rights (AHTEG-FR) collecting together views, experiences, and best practices to produce an inventory and options for encouraging, guidi

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Kamm, F. M. "MORAL STATUS AND PERSONAL IDENTITY: CLONES, EMBRYOS, AND FUTURE GENERATIONS." Social Philosophy and Policy 22, no. 2 (2005): 283–307. http://dx.doi.org/10.1017/s0265052505052118.

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In the first part of this article, I argue that even those entities that in their own right and for their own sake give us reason not to destroy them and to help them are sometimes substitutable for the good of other entities. In so arguing, I consider the idea of being valuable as an end in virtue of intrinsic and extrinsic properties. I also conclude that entities that have claims to things and against others are especially nonsubstitutable. In the second part, I argue that cloning poses no threat to the nonsubstitutability of these entities (and in this sense, to the dignity of persons). I

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Reflinur, Reflinur, Puji Lestari, and Suk-Ha Lee. "THE POTENTIAL USE OF SSR MARKERS TO SUPPORT THE MORPHOLOGICAL IDENTIFICATION OF INDONESIAN MUNGBEAN VARIETIES." Indonesian Journal of Agricultural Science 17, no. 2 (2017): 65. http://dx.doi.org/10.21082/ijas.v17n2.2016.p65-74.

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<p>Mungbean varieties were mainly characterized based on morphological traits. Molecular genetic approach is expected to help the breeder in identification of mungbean varieties in more detail and to protect intellectual property right. This study aimed to identify Indonesian mungbean varieties based on DNA fingerprint profile using a marker set to support morphological characters. A total of 22 Indonesian mungbean accessions were characterized based on 21 morphological traits and 55 simple sequence repeats (SSRs) primers. Of the total 22 mungbean varieties used in the present study, 16

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Lesch, B. J., A. R. Gehrke, M. L. Bulyk, and C. I. Bargmann. "Transcriptional regulation and stabilization of left-right neuronal identity in C. elegans." Genes & Development 23, no. 3 (2009): 345–58. http://dx.doi.org/10.1101/gad.1763509.

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Penchaszadeh, Victor B., and Lavinia Schuler-Faccini. "Genetics and human rights: Two histories: restoring genetic identity after forced disappearance and identity suppression in Argentina and after compulsory isolation for leprosy in Brazil." Genetics and Molecular Biology 37, no. 1 suppl 1 (2014): 299–304. http://dx.doi.org/10.1590/s1415-47572014000200016.

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Widaningsih, Nina Agusti, Edi Purwanto, N. Nandariyah, and R. Reflinur. "The Use of DNA Microsatellite Markers for Genetic Diversity Identifi cation of Soybean (Glycine max (L) Meriil.) as a Supplementary Method in Reference Collections Management." Indonesian Journal of Biotechnology 19, no. 2 (2016): 136. http://dx.doi.org/10.22146/ijbiotech.9306.

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Large number of new soybean varieties are mostly derived from crosses of elite genotypes resulted ina narrowing of both the genetic diversity and the phylogenetic relationship between soybean varieties. Thus,discrimination among soybean varieties is becoming more diffi cult, especially when morphological traits wereapplied. In Plant Variety Protection (PVP) system, new varieties of soybeans including granted PVP right, localand breeding varieties registered in PVP offi ce were frequently increased, implicate on increasingly the numberof soybean varieties collections. To assist the management o

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Akhtyrska, Nataliia M., and Olena Yu Kostiuchenko. "LEGAL REGULATION OF BIOETHICAL ISSUES IN THE LIGHT OF MEDICAL SCIENCE ACHIEVEMENTS." Wiadomości Lekarskie 73, no. 12 (2020): 2804–9. http://dx.doi.org/10.36740/wlek202012217.

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The aim: To identify issues of legal support for the use of genetics' advances in medicine, reproductive technologies, etc. and to identify criteria for admissibility of safe and ethical implementation of scientific results. Materials and methods: The analysis of international acts, legislation of European countries, scientific reports on the results of achievements in medicine, in particular, the study and modification of DNA. Decisions of the European Court of Human Rights and a sample survey were used. The study is based on a combination of philosophical approaches, theoretical (dialectical

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MURPHY, TIMOTHY F. "Sex before the State: Civic Sex, Reproductive Innovations, and Gendered Parental Identity." Cambridge Quarterly of Healthcare Ethics 26, no. 2 (2017): 267–77. http://dx.doi.org/10.1017/s0963180116000864.

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Abstract:Certain changes in the way that states classify people by sex as well as certain reproductive innovations undercut the rationale for state identification of people as male or female in signifying gendered parental relationships to children. At present, people known to the state as men may be genetic mothers to their children; people known to the state as women may be genetic fathers to their children. Synthetic gametes would make it possible for transgender men to be genetically related to children as fathers and transgender women to be genetically related to children as mothers, even

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Sánchez Vilanova, María. "A propósito de la inalterabilidad e intangibilidad del patrimonio genético humano como bien digno de protección penal | About the inalterability and the intangibility of the human genetic inheritance as a legally-protected interest." Cuadernos Electrónicos de Filosofía del Derecho, no. 41 (December 27, 2019): 136. http://dx.doi.org/10.7203/cefd.41.13912.

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 RESUMEN. En el presente estudio se efectúa una reflexión sobre el delito de manipulación genética contemplado en el artículo 159 del Código penal, precepto cuya concreta regulación despierta numerosas objeciones, especialmente en atención al bien jurídico de carácter colectivo que protege, como es la identidad genética, cuestionándose si esta conducta en particular encontraría mejor acomodo en la legislación administrativa.   ABSTRACT. This paper makes a reflection on the crime of genetic manipulation contemplated in Article 159 of the Criminal Code, a provision whose specif

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Zozula, Jolanta. "Presumption of the child’s origin from the husband of the mother within 300 days of marriage termination or annulment, and in the event of judicial separation – de lege lata and de lege ferenda remarks." Problemy Opiekuńczo-Wychowawcze 584, no. 9 (2019): 33–46. http://dx.doi.org/10.5604/01.3001.0013.6019.

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The article is dedicated to the institution of the presumption of the child's origin from the husband of the mother as one of three ways to determine the child's origin from the father. In the opinion of the author, with the current availability of genetic tests (DNA), the regulation “extending” this presumption to children born after the termination or annulment of marriage, after the judicial separation and declaring any of the parents to be deceased, does not implement the principle of protecting the good of the child and in particular his right to grow up in the family and the identity rig

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Lin, Michael M. J. "Conferring a Federal Property Right in Genetic Material: Stepping into the Future with the Genetic Privacy Act." American Journal of Law & Medicine 22, no. 1 (1996): 109–34. http://dx.doi.org/10.1017/s0098858800010315.

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“A wise man can hear profit in the wind.”—Pel, quoting the Ferengi Rules of AcquisitionThe expansive biotechnology field includes many facets of medical research, from drug discovery and design, to gene therapy and the diagnosis of genetic diseases, to the use of deoxyribonucleic acid (DNA) evidence to identify individuals and genetic characteristics. The biotechnology industry requires a readily available supply of biological raw materials; much of current research is founded on cells, tissues, organs, fetal tissues and placentas, and other samples derived from human donors. However, this gro

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Dominguez, Geraldina, Timothy R. Dambaugh, Felicia R. Stamey, Stephen Dewhurst, Naoki Inoue, and Philip E. Pellett. "Human Herpesvirus 6B Genome Sequence: Coding Content and Comparison with Human Herpesvirus 6A." Journal of Virology 73, no. 10 (1999): 8040–52. http://dx.doi.org/10.1128/jvi.73.10.8040-8052.1999.

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ABSTRACT Human herpesvirus 6 variants A and B (HHV-6A and HHV-6B) are closely related viruses that can be readily distinguished by comparison of restriction endonuclease profiles and nucleotide sequences. The viruses are similar with respect to genomic and genetic organization, and their genomes cross-hybridize extensively, but they differ in biological and epidemiologic features. Differences include infectivity of T-cell lines, patterns of reactivity with monoclonal antibodies, and disease associations. Here we report the complete genome sequence of HHV-6B strain Z29 [HHV-6B(Z29)], describe i

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Paez, Eze. "A Kantian ethics of paradise engineering." Analysis 80, no. 2 (2019): 283–93. http://dx.doi.org/10.1093/analys/anz077.

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Abstract Wild animals probably have net negative lives. Christine Korsgaard rejects the view that we might engineer paradise by redesigning nature and animals so that they have the best possible existences. She believes the genetic changes required would not be identity-preserving, thereby causing animals to cease to exist. I argue, first, that paradise engineering is permissible. Many harms are caused by non-sentient natural entities and processes. Moreover, sentient animals can survive modifications compatible with their psychological persistence over time. Second, we are required to re-engi

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Ravelingien, An, and Guido Pennings. "On the Right to Know and The Use of Double Standards: Response to Open Peer Commentaries on “The Right to Know Your Genetic Parents: From Open Identity Gamete Donation to Routine Paternity Testing”." American Journal of Bioethics 13, no. 5 (2013): W6—W8. http://dx.doi.org/10.1080/15265161.2013.781365.

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Nakamura, Yoshiaki, Kohei Shitara, and Jeeyun Lee. "The Right Treatment of the Right Patient: Integrating Genetic Profiling Into Clinical Decision Making in Advanced Gastric Cancer in Asia." American Society of Clinical Oncology Educational Book, no. 41 (June 2021): e166-e173. http://dx.doi.org/10.1200/edbk_321247.

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Gastric cancer is a major global health burden, especially when patients are diagnosed with recurrent or metastatic gastric cancer. Despite recent advances in treatment options with palliative chemotherapy, the median overall survival of patients with gastric cancer remains within 1 or 2 years after the diagnosis of metastatic disease. Gastric cancer is significantly more prevalent in eastern Asia (e.g., Japan and Korea). Next-generation sequencing is rapidly being adopted as part of clinical practice in Korea and Japan, especially in patients with gastric cancer. Approximately 10% to 15% of t

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Babcock, Michael C., R. Steven Stowers, Jennifer Leither, Corey S. Goodman, and Leo J. Pallanck. "A Genetic Screen for Synaptic Transmission Mutants Mapping to the Right Arm of Chromosome 3 in Drosophila." Genetics 165, no. 1 (2003): 171–83. http://dx.doi.org/10.1093/genetics/165.1.171.

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Abstract Neuronal function depends upon the proper formation of synaptic connections and rapid communication at these sites, primarily through the regulated exocytosis of chemical neurotransmitters. Recent biochemical and genomic studies have identified a large number of candidate molecules that may function in these processes. To complement these studies, we are pursuing a genetic approach to identify genes affecting synaptic transmission in the Drosophila visual system. Our screening approach involves a recently described genetic method allowing efficient production of mosaic flies whose eye

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Pinto, Yaïr, H. Steven Scholte, and V. A. F. Lamme. "Tracking Moving Identities: After Attending the Right Location, the Identity Does Not Come for Free." PLoS ONE 7, no. 8 (2012): e42929. http://dx.doi.org/10.1371/journal.pone.0042929.

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Jović-Prlainović, Olga. "Judgments of the European court of human rights v. The Republic of Serbia on the application of genetic testing in paternity litigation." Strani pravni zivot, no. 1 (2021): 47–61. http://dx.doi.org/10.5937/spz65-30886.

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The case law of the European Court of Human Rights is of great importance for the formulation of human rights standards as it applies the European Convention on Human Rights by interpreting the prescribed rights and freedoms taking into account social reality and legal regulation in Council of Europe member states. When joining this political organization the Republic of Serbia carried out the procedures of adjusting the legislation to the convention requirements, so that, in normative sense, Serbian family law systematically follows modern standards of human rights protection. The decisions o

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Wilhelmsen, Fredrik. "‘The Wife Would Put on a Nice Suit, Hat, and Possibly Gloves’: The Misogynistic Identity Politics of Anders Behring Breivik." Fascism 10, no. 1 (2021): 108–33. http://dx.doi.org/10.1163/22116257-10010003.

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Abstract By analysing the anti-feminist and misogynistic narratives in Anders Behring Breivik’s compendium 2083: A European Declaration of Independence, this article argues that Breivik’s counterjihadist worldview can be located both as a permutation of ‘generic fascism’ and as a form of nonegalitarian ‘identity politics’. First, the article reframes and reformulates Nancy Fraser’s concept of identity politics, as it sets Breivik’s ideology in relation to her theory of a ‘politics of recognition’, arguing that her theories – originally developed to analyse left-wing politics – can be used to i

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Wang, Lei, Wei Kong, and Shuaiqun Wang. "Detecting genetic associations with brain imaging phenotypes in Alzheimer’s disease via a novel structured KCCA approach." Journal of Bioinformatics and Computational Biology 19, no. 04 (2021): 2150012. http://dx.doi.org/10.1142/s0219720021500128.

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Neuroimaging genetics has become an important research topic since it can reveal complex associations between genetic variants (i.e. single nucleotide polymorphisms (SNPs) and the structures or functions of the human brain. However, existing kernel mapping is difficult to directly use the sparse representation method in the kernel feature space, which makes it difficult for most existing sparse canonical correlation analysis (SCCA) methods to be directly promoted in the kernel feature space. To bridge this gap, we adopt a novel alternating projected gradient approach, gradient KCCA (gradKCCA)

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Parrotta, Elvira Immacolata, Anna Procopio, Stefania Scalise, et al. "Deciphering the Role of Wnt and Rho Signaling Pathway in iPSC-Derived ARVC Cardiomyocytes by In Silico Mathematical Modeling." International Journal of Molecular Sciences 22, no. 4 (2021): 2004. http://dx.doi.org/10.3390/ijms22042004.

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Arrhythmogenic Right Ventricular cardiomyopathy (ARVC) is an inherited cardiac muscle disease linked to genetic deficiency in components of the desmosomes. The disease is characterized by progressive fibro-fatty replacement of the right ventricle, which acts as a substrate for arrhythmias and sudden cardiac death. The molecular mechanisms underpinning ARVC are largely unknown. Here we propose a mathematical model for investigating the molecular dynamics underlying heart remodeling and the loss of cardiac myocytes identity during ARVC. Our methodology is based on three computational models: fir

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Roberts, Dorothy, and Sujatha Jesudason. "MOVEMENT INTERSECTIONALITY." Du Bois Review: Social Science Research on Race 10, no. 2 (2013): 313–28. http://dx.doi.org/10.1017/s1742058x13000210.

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AbstractIntersectional analysis need not focus solely on differences within or between identity-based groups. Using intersectionality for cross movement mobilization reveals that, contrary to criticism for being divisive, attention to intersecting identities has the potential to create solidarity and cohesion. In this article, we elaborate this argument with a case study of the intersection of race, gender, and disability in genetic technologies as well as in organizing to promote a social justice approach to the use of these technologies. We show how organizing based on an intersectional anal

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Tuzhilova-Ordanskaya, E. M., and E. V. Akhtyamova. "Issues of Civil Law Regulation Regarding the Protection of Civil Rights When Using Genetic Information." Вестник Пермского университета. Юридические науки, no. 52 (2021): 263–84. http://dx.doi.org/10.17072/1995-4190-2021-52-263-284.

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Introduction: the article deals with some basic legal issues that arise from the use of human genetic information. There exist some issues of defining the legal nature of such information, which we identify in the article. Current legal regulation is not able to take into account the peculiarities of genetic information and provide an effective protection against the misappropriation and improper use of genetic information when carrying out genetic diagnostics, working with biomaterials. At the moment, special public law and civil law regulation of the procedure for obtaining, accumulating, pr

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Hillgruber, Christian. "Der manipulierbare Embryo." Jahrbuch für Recht und Ethik / Annual Review of Law and Ethics 28, no. 1 (2020): 39–52. http://dx.doi.org/10.3790/jre.28.1.39.

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The guarantee of human dignity (article 1 paragraph 1 German Basic Law) requires the protection of the embryo’s identity and – in accordance with further requirements of article 2 paragraph 2 sentence 1 German Basic Law – the protection of its physical integrity. Every human being has, even in his earliest, prenatal stage of development, an unconditional right to be and remain a human being, derived from his dignity. In order to protect his right to species-specific development, the embryo must also be protected from any dehumanization. This categorically excludes any mixing of its genetic mat

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Cabot, E. L., P. Doshi, M. L. Wu, and C. I. Wu. "Population genetics of tandem repeats in centromeric heterochromatin: unequal crossing over and chromosomal divergence at the Responder locus of Drosophila melanogaster." Genetics 135, no. 2 (1993): 477–87. http://dx.doi.org/10.1093/genetics/135.2.477.

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Abstract The Responder (Rsp) locus in Drosophila melanogaster is the target locus of segregation distortion and is known to be comprised of a tandem array of 120-bp repetitive sequences. In this study, we first determined the large scale molecular structure of the Rsp locus, which extends over a region of 600 kb on the standard sensitive (cn bw) chromosome. Within the region, small Rsp repeat arrays are interspersed with non-Rsp sequences and account for 10-20% of the total sequences. We isolated and sequenced 32 Rsp clones from three different chromosomes. The main results are: (1) Rsp repeat

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Marchant, G. E., and D. G. Holm. "Genetic analysis of the heterochromatin of chromosome 3 in Drosophila melanogaster. I. Products of compound-autosome detachment." Genetics 120, no. 2 (1988): 503–17. http://dx.doi.org/10.1093/genetics/120.2.503.

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Abstract The heterochromatin of the third chromosome is the largest uncharacterized region of the Drosophila melanogaster genome, and the last major block of D. melanogaster heterochromatin to be thoroughly analyzed. In the present study, this region was genetically dissected by generating and analyzing a series of attached, detached and reattached third chromosomes. Separate detachment experiments were conducted for all 12 possible combinations of four newly synthesized sister-strand compound-3L and three newly synthesized sister-strand compound-3R chromosomes. A total of 443 recessive lethal

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О. L., Lvovа, and Ivaniv I. R. "The moral and legal foundations of bioethics in the context of human rights: legal theory and international practice." Almanac of law: The role of legal doctrine in ensuring of human rights 11, no. 11 (2020): 327–33. http://dx.doi.org/10.33663/2524-017x-2020-11-55.

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Modern processes of globalization taking place in the field of law are a great challenge to the idea of human nature, which is recognized in Ukraine as the highest social value, as well as to the concept and essence of law itself. In our opinion, this is a threat on a global scale and necessitates the search for an adequate response to the threat from the scientific and technical process in the field of biomedicine, both for the natural (physical) existence of man and the preservation of his moral identity. In fact, these foundations have become the prerequisites for the development of the sci

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Singh, Gurjeet, and Amar J. S. Klar. "The 2.1-kb Inverted Repeat DNA Sequences Flank themat2,3Silent Region in Two Species of Schizosaccharomyces and Are Involved in Epigenetic Silencing inSchizosaccharomyces pombe." Genetics 162, no. 2 (2002): 591–602. http://dx.doi.org/10.1093/genetics/162.2.591.

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AbstractThe mat2,3 region of the fission yeast Schizosaccharomyces pombe exhibits a phenomenon of transcriptional silencing. This region is flanked by two identical DNA sequence elements, 2.1 kb in length, present in inverted orientation: IRL on the left and IRR on the right of the silent region. The repeats do not encode any ORF. The inverted repeat DNA region is also present in a newly identified related species, which we named S. kambucha. Interestingly, the left and right repeats share perfect identity within a species, but show ∼2% bases interspecies variation. Deletion of IRL results in

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English, Milton A., Lin Lei, Margot Giannetti, Susan E. Lyons, and Paul P. Liu. "A Genetic Screen for Zebrafish Mutants Affecting Early Hematopoiesis." Blood 104, no. 11 (2004): 1702. http://dx.doi.org/10.1182/blood.v104.11.1702.1702.

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Abstract Hematopoiesis, or blood cell formation, starts from hematopoietic stem cells and goes through many rounds of cell proliferation and a number of commitment steps that progressively restrict cells to a particular lineage. The generation and maintenance of stem cell pool and the regulation of lineage commitment are poorly understood. Right now there is only one reported zebrafish mutant, cloche, that has defects in early hematopoiesis. We have undertaken a chemical mutagenesis screen using ENU in the zebrafish to uncover mutants in early hematopoiesis. Haploid embryos from F1 females wer

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Dupré, John. "Are There Genes?" Royal Institute of Philosophy Supplement 56 (March 2005): 193–210. http://dx.doi.org/10.1017/s1358246100008845.

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Contrary to one possible interpretation of my title, this paper will not advocate any scepticism or ontological deflation. My concern will rather be with how we should best think about a realm of phenomena the existence of which is in no doubt, what has traditionally been referred to as the genetic. I have no intention of questioning a very well established scientific consensus on this domain. It involves the chemical DNA, which resides in almost all our cells, which is capable of producing copies of itself that accurately reproduce a very long sequence of components, and which plays a role in

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Dupré, John. "Are There Genes?" Royal Institute of Philosophy Supplement 56 (December 2005): 16–17. http://dx.doi.org/10.1017/s1358246105056092.

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Contrary to one possible interpretation of my title, this paper will not advocate any scepticism or ontological deflation. My concern will rather be with how we should best think about a realm of phenomena the existence of which is in no doubt, what has traditionally been referred to as the genetic. I have no intention of questioning a very well established scientific consensus on this domain. It involves the chemical DNA, which resides in almost all our cells, which is capable of producing copies of itself that accurately reproduce a very long sequence of components, and which plays a role in

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Mohr, Stephanie E., and Robert E. Boswell. "Genetic Analysis of Drosophila melanogaster Polytene Chromosome Region 44D–45F: Loci Required for Viability and Fertility." Genetics 160, no. 4 (2002): 1503–10. http://dx.doi.org/10.1093/genetics/160.4.1503.

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Abstract A genetic screen to identify mutations in genes in the 45A region on the right arm of chromosome 2 that are involved in oogenesis in Drosophila was undertaken. Several lethal but no female sterile mutations in the region had previously been identified in screens for P-element insertion or utilizing X rays or EMS as a mutagen. Here we report the identification of EMS-induced mutations in 21 essential loci in the 45D–45F region, including 13 previously unidentified loci. In addition, we isolated three mutant alleles of a newly identified locus required for fertility, sine prole. Mutatio

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Khairunas, Muhammad Zarlis, and Sawaluddin. "Data Security Analysis Against Chosen Ciphertext Secure Public Key Attack Using Threshold Encryption Scheme." Randwick International of Social Science Journal 2, no. 3 (2021): 326–34. http://dx.doi.org/10.47175/rissj.v2i3.275.

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A public key encryption cryptography system can be utilized to generate ciphertext of a message using a public key. However, this public key encryption cryptography system cannot be utilized if you want to generate ciphertext using several different keys. Solving the problems above can use the Chosen Ciphertext Secure Public Key Threshold Encryption scheme but are the securities from Threshold Encryption really strong in securing messages, therefore the above problems can be analyzed for Data Security Against Chosen Ciphertext Secure Public Key Attacks Using Threshold Encryption Schemes. The w

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Gilroy, Paul. "“Rhythm in the Force of Forces”." Critical Times 2, no. 3 (2019): 370–95. http://dx.doi.org/10.1215/26410478-7862525.

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Abstract This essay is addressed to discrepancies between musical and political time. It uses the death of Hugh Masekela to consider the changing pattern of intergenerational relationships and the place of music within local and transnational freedom movements. The impact of technological change on the mediation of political solidarity is then examined through two principal examples: the elaboration of generic racial identity and the weaponization of culture and information by the alt-right and its fellow travelers.

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Biddle, Fred G., and Brenda A. Eales. "Lateral asymmetry of paw usage: phenotypic survey of constitutive and experience-conditioned paw-usage behaviours among common strains of the mouse." Genome 44, no. 4 (2001): 539–48. http://dx.doi.org/10.1139/g01-045.

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Left-right direction of paw usage in the mouse is defined by the right-paw entry (RPE) score, which is the number of reaches with the right paw to retrieve food from a small food tube in a total of 50 right- and left-paw reaches. Two qualitatively different paw-usage behaviours can be identified by the difference in the RPE scores from naive mice in left- or right-biased test chambers and their retest, 1 week later, in the opposite-biased test chamber. In mice with constitutive paw usage, the RPE score may respond to the direction of a biased test chamber, but it returns to the value that is e

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Williams, David V. "Ko Aotearoa Tenei: Law and Policy Affecting Maori Culture and Identity." International Journal of Cultural Property 20, no. 3 (2013): 311–31. http://dx.doi.org/10.1017/s0940739113000143.

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AbstractIn July 2011 what is commonly known as the Wai 262 Report was released. After a protracted series of hearings, dating back to 1997, the New Zealand Waitangi Tribunal has at last reported on the some of the wide range of issues canvassed in those hearings. Three beautifully illustrated volumes contain a large number of recommendations in what is described as a whole-of-government report. This article notes earlier comments on Wai 262 in this journal and reframes what is often known as the ‘Maori renaissance’ from which this claim emerged in 1991. The Tribunal decided not to discuss hist

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Bisgrove, B. W., J. J. Essner, and H. J. Yost. "Multiple pathways in the midline regulate concordant brain, heart and gut left-right asymmetry." Development 127, no. 16 (2000): 3567–79. http://dx.doi.org/10.1242/dev.127.16.3567.

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The embryonic midline in vertebrates has been implicated in left-right development, but the mechanisms by which it regulates left-right asymmetric gene expression and organ morphogenesis are unknown. Zebrafish embryos have three domains of left-right asymmetric gene expression that are useful predictors of organ situs. cyclops (nodal), lefty1 and pitx2 are expressed in the left diencephalon; cyclops, lefty2 and pitx2 are expressed in the left heart field; and cyclops and pitx2 are expressed in the left gut primordium. Distinct alterations of these expression patterns in zebrafish midline mutan

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Cheong, Agnes, Rinat Degani, Kimberly D. Tremblay, and Jesse Mager. "A null allele of Dnaaf2 displays embryonic lethality and mimics human ciliary dyskinesia." Human Molecular Genetics 28, no. 16 (2019): 2775–84. http://dx.doi.org/10.1093/hmg/ddz106.

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Abstract The dynein axonemal assembly factor (Dnaaf) protein family is involved in preassembly and stability of dynein arms before they are transported into the cilia. In humans, mutations in DNAAF genes lead to several diseases related to cilia defects such as primary ciliary dyskinesia (PCD; OMIM: 612518). Patients with PCD experience malfunctions in cilia motility, which can result in inflammation and infection of the respiratory tract among other defects. Previous studies have identified that a mutation in DNAAF2 results in PCD and that 40% of these patients also experience laterality defe

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KANG, Phee Seng. "複製或不複製？——基因複製的倫理震撼". International Journal of Chinese & Comparative Philosophy of Medicine 1, № 3 (1998): 95–123. http://dx.doi.org/10.24112/ijccpm.11343.

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LANGUAGE NOTE | Document text in Chinese; abstract also in English.複製人實質上就是複製活過或仍活著的人的基因組合。本文嘗試就下列五方面探討體胞核移植法在人類身上的應用所引起的社會倫理問題。（一）基因等同：兩個人是否可以共有同一基因組合？（二）基因歷史：複製者的基因並非是一個新的、獨特的基因組合。這基因曾有的（即被複製者的）歷史對複製者是否有負面影響？（三）基因傳遞方式：無性生殖方式的基因傳遞對複製者是否有負面影響？（四）基因複製風險：複製帶給複製者什麼風險？（五）基因複製權：基因複製權衍生出什麼倫理問題？對全面支持複製科技在人類的應用的論者來說，複製只是另類生殖方法，提供人多一個生殖途徑的選擇。複製對他人並無傷害，對社會沒有負面影響。既或有任何傷害或影響，也都是可以接受的。因此，在一般的情況下，複製人科技不應該遭受社會的禁止。本文的討論顯示這是過度樂觀的看法。以「基因複製產生身分混淆」的反對說法固然不成立。然而，基因通往的歷史，無性生殖的方式，複製初階的風險，以及棘手的基因複製法律問題及由此再衍生的倫理問題等，這些對複製孩子，人倫關係，家庭結構及社會穩定所可能造成的負面衝擊和嚴重傷害是不容忽視的。複製人科技即使可行，也應該在極嚴格的監管下進行。更重要的是，複製人的社會倫理震撼是國際社會的共同關注。因此，複製人的支持

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