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Artigos de revistas sobre o assunto "SRD5A1"

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Khantham, Chiranan, Wipawadee Yooin, Korawan Sringarm, et al. "Effects on Steroid 5-Alpha Reductase Gene Expression of Thai Rice Bran Extracts and Molecular Dynamics Study on SRD5A2." Biology 10, no. 4 (2021): 319. http://dx.doi.org/10.3390/biology10040319.

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Steroid 5-alpha reductases (SRD5As) are responsible for the conversion of testosterone to dihydrotestosterone, a potent androgen, which is the aetiologic factor of androgenetic alopecia. This study aimed to compare the SRD5A gene expression suppression activity exerted by Thai rice bran extracts and their components and investigate the interactional mechanism between bioactive compounds and SRD5A2 using molecular dynamics (MD) simulation. Bran of Oryza sativa cv. Tubtim Chumphae (TRB), Yamuechaebia Morchor (YRB), Riceberry (RRB), and Malinil Surin (MRB), all rice milling by-products, was solve
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Das, Kakoli, Pia D. N. Lorena, Lai Kuan Ng та ін. "Differential expression of steroid 5α-reductase isozymes and association with disease severity and angiogenic genes predict their biological role in prostate cancer". Endocrine-Related Cancer 17, № 3 (2010): 757–70. http://dx.doi.org/10.1677/erc-10-0022.

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The biological role of steroid 5α-reductase isozymes (encoded by the SRD5A1 and SRD5A2 genes) and angiogenic factors that play important roles in the pathogenesis and vascularization of prostate cancer (PC) is poorly understood. The sub-cellular expression of these isozymes and vascular endothelial growth factor (VEGF) in PC tissue microarrays (n=62) was examined using immunohistochemistry. The effect of SRD5A inhibition on the angiogenesis pathway genes in PC was also examined in prostate cell lines, LNCaP, PC3, and RWPE-1, by treating them with the SRD5A inhibitors finasteride and dutasterid
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Goodarzi, Mark O., Nissar A. Shah, Heath J. Antoine, Marita Pall, Xiuqing Guo та Ricardo Azziz. "Variants in the 5α-Reductase Type 1 and Type 2 Genes Are Associated with Polycystic Ovary Syndrome and the Severity of Hirsutism in Affected Women". Journal of Clinical Endocrinology & Metabolism 91, № 10 (2006): 4085–91. http://dx.doi.org/10.1210/jc.2006-0227.

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Abstract Context: Despite the importance of dihydrotestosterone in androgen action, polymorphisms in the genes for the two isoforms of 5α-reductase (SRD5A1 and SRD5A2) have not been evaluated as risk factors for polycystic ovary syndrome (PCOS). Objective: The objective of the study was to test the hypothesis that haplotypes in the SRD5A1 and SRD5A2 genes are risk factors for PCOS and the severity of hirsutism in affected women. Design: PCOS and control subjects were genotyped for seven single-nucleotide polymorphisms in SRD5A1 and eight single-nucleotide polymorphisms in SRD5A2. Haplotypes we
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Ruksiriwanich, Warintorn, Chiranan Khantham, Pichchapa Linsaenkart, et al. "In Vitro and In Vivo Regulation of SRD5A mRNA Expression of Supercritical Carbon Dioxide Extract from Asparagus racemosus Willd. Root as Anti-Sebum and Pore-Minimizing Active Ingredients." Molecules 27, no. 5 (2022): 1535. http://dx.doi.org/10.3390/molecules27051535.

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Oily skin from overactive sebaceous glands affects self-confidence and personality. There is report of an association between steroid 5-alpha reductase gene (SRD5A) expression and facial sebum production. There is no study of the effect of Asparagus racemosus Willd. root extract on the regulation of SRD5A mRNA expression and anti-sebum efficacy. This study extracted A. racemosus using the supercritical carbon dioxide fluid technique with ethanol and investigated its biological compounds and activities. The A. racemosus root extract had a high content of polyphenolic compounds, including querce
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Chen, Erbao, Jing Yi, Qingqi Ren, Yuanna Mi, Zhe Gan, and Jikui Liu. "Overexpression of SRD5A3 in Hepatocellular Carcinoma and Its Molecular Mechanism: A Study of Bioinformatics Exploration Analysis with Experimental Verification." Evidence-Based Complementary and Alternative Medicine 2022 (September 16, 2022): 1–14. http://dx.doi.org/10.1155/2022/7853168.

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Background. Hepatocellular carcinoma (HCC) is one of the most common cancers worldwide, and more prevalent among males than females. However, the biological role of enzyme 5α-reductase (SRD5A3), which plays a critical role in the androgen receptor signaling pathway during HCC development, remains poorly understood. Methods. ONCOMINE, GEPIA, UALCAN, and Kaplan–Meier Plotter were used to analyze the expression and prognostic value of SRD5A3 in HCC. STRING and Metascape were applied to analyze potential target and molecular pathways underlying SRD5A3 in HCC. A real-time quantitative reverse trans
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Basaria, Shehzad, Ravi Jasuja, Grace Huang, et al. "Characteristics of Men Who Report Persistent Sexual Symptoms After Finasteride Use for Hair Loss." Journal of Clinical Endocrinology & Metabolism 101, no. 12 (2016): 4669–80. http://dx.doi.org/10.1210/jc.2016-2726.

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Context: Some men who use finasteride for hair loss report persistent sexual and other symptoms after discontinuing finasteride therapy. Objective: To determine whether these persistent symptoms after discontinuation of finasteride use are due to androgen deficiency, decreased peripheral androgen action, or persistent inhibition of steroid 5α-reductase (SRD5A) enzymes. Participants: Finasteride users, who reported persistent sexual symptoms after discontinuing finasteride (group 1); age-matched finasteride users who did not report sexual symptoms (group 2); and healthy men who had never used f
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Melcangi, Roberto Cosimo, Livio Casarini, Marco Marino, et al. "Altered methylation pattern of the SRD5A2 gene in the cerebrospinal fluid of post-finasteride patients: a pilot study." Endocrine Connections 8, no. 8 (2019): 1118–25. http://dx.doi.org/10.1530/ec-19-0199.

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Context Post-finasteride syndrome (PFS) occurs in patients with androgenic alopecia after suspension of the finasteride treatment, leading to a large variety of persistent side effects. Despite the severity of the clinical picture, the mechanism underlying the PFS symptoms onset and persistence is still unclear. Objective To study whether epigenetic modifications occur in PFS patients. Methods Retrospective analysis of a multicentric, prospective, longitudinal, case–control clinical trial, enrolling 16 PFS patients, compared to 20 age-matched healthy men. Main outcomes were methylation pattern
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Ruksiriwanich, Warintorn, Chiranan Khantham, Anurak Muangsanguan, et al. "Guava (Psidium guajava L.) Leaf Extract as Bioactive Substances for Anti-Androgen and Antioxidant Activities." Plants 11, no. 24 (2022): 3514. http://dx.doi.org/10.3390/plants11243514.

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Leaves of guava (Psidium guajava L.) have been used in Thai folk medicine without any supporting evidence as a traditional herbal remedy for hair loss. Androgenetic alopecia (AGA) is chronic hair loss caused by effects of androgens in those with a genetic predisposition, resulting in hair follicle miniaturization. Our objectives were to provide the mechanistic assessment of guava leaf extract on gene expressions related to the androgen pathway in well-known in vitro models, hair follicle dermal papilla cells (HFDPC), and human prostate cancer cells (DU-145), and to determine its bioactive cons
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Cortés-Pavía, Iván, Abel Moreno-Cárcamo, Abraham Landa-Piedra, and Marisa Cabeza. "Largo trabajo y mucho que resolver aún sobre las isoenzimas de la 5-alfa reductasa Revisión bibliográfica." Latin American Journal of Development 6, no. 2 (2024): e2358. http://dx.doi.org/10.46814/lajdv6n2-009.

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Este trabajo revisa los principales artículos relacionados con la actividad de la enzima 5α-reductasa (SRD5A) y las patologías andrógeno-dependientes como la hiperplasia prostática benigna, el cáncer de próstata, acné y la calvicie androgénica entre otras. Con este propósito, se revisaron diferentes plataformas como Medline, Scopus y Science Direct, utilizando como indicadores las palabras 5α-reductasa, isoenzimas y patologías andrógeno- dependientes. Con esta clasificación se encontraron artículos clásicos de décadas anteriores y nuevos artículos en donde aparece ya descrita, la estructura de
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Lassche, Gerben, Yuichiro Tada, Carla M. L. van Herpen, et al. "Predictive and Prognostic Biomarker Identification in a Large Cohort of Androgen Receptor-Positive Salivary Duct Carcinoma Patients Scheduled for Combined Androgen Blockade." Cancers 13, no. 14 (2021): 3527. http://dx.doi.org/10.3390/cancers13143527.

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Patients suffering from recurrent or metastatic (R/M) salivary duct carcinoma (SDC) are often treated with combined androgen blockade (CAB). However, CAB frequently fails, resulting in a worse prognosis. Therefore, biomarkers that can predict treatment failure are urgently needed. mRNA from 76 R/M androgen receptor (AR)-positive SDC patients treated with leuprorelin acetate combined with bicalutamide was extracted from pre-treatment tumor specimens. AR, Notch, MAPK, TGFβ, estrogen receptor (ER), Hedgehog (HH), and PI3K signaling pathway activity scores (PAS) were determined based on the expres
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Teses / dissertações sobre o assunto "SRD5A1"

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Tijani, Omolara Khadijat. "Glucocorticoids and Intracrine Cortisol Metabolism in human Islets : Impact on Glucose Stimulated Insulin secretion." Electronic Thesis or Diss., Université de Lille (2022-....), 2024. http://www.theses.fr/2024ULILS061.

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Une exposition excessive aux glucocorticoïdes (GC), comme observée chez les patients recevant une corticothérapie, peut entraîner un dysfonctionnement des cellules β et un diabète chez jusqu'à 40% des patients. Dans l'obésité, une surexposition locale au cortisol secondaire à une altération du métabolisme du cortisol contribue à l'apparition du diabète. Des doses élevées de GC comme la dexaméthasone (DEX) inhibent la sécrétion d'insuline stimulée par le glucose (SISG), mais les effets de doses plus faibles et des autres GC, tels que l'hydrocortisone (HC) et la prednisone (PRED), restent peu ét
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Calais, Flávia Leme 1983. "Estudo dos genes SRD5A2 e 17BHSD3 em casos de ambiguidade genital em pacientes com cariótipo 46,XY." [s.n.], 2010. http://repositorio.unicamp.br/jspui/handle/REPOSIP/317125.

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Orientador: Maricilda Palandi de Mello<br>Dissertação (mestrado) - Universidade Estadual de Campinas, Instituto de Biologia<br>Made available in DSpace on 2018-08-17T10:04:15Z (GMT). No. of bitstreams: 1 Calais_FlaviaLeme_M.pdf: 2545885 bytes, checksum: 01651078ede5d0d74599fe9cf524b8bd (MD5) Previous issue date: 2010<br>Resumo: Para um correto desenvolvimento sexual masculino em humanos, é necessária a presença, entre outros, de dois hormônios esteróides: a testosterona (T) e a diidrotestosterona (DHT). A T é o hormônio responsável pelo desenvolvimento da genitália interna masculina, já a DH
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Medina-Cano, Daniel. "Study of the molecular bases underlying cerebellar defects with emphasis on protein N-glycosylation impairment." Thesis, Sorbonne Paris Cité, 2018. https://wo.app.u-paris.fr/cgi-bin/WebObjects/TheseWeb.woa/wa/show?t=2162&f=12708.

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Les anomalies cérébelleuses englobent un groupe de maladies rares affectant le fonctionnement du cervelet. La prévalence de ces défauts est estimée à 26 sur 10000 enfants en Europe. Ces maladies entraînent des troubles du mouvement (ataxie) et sont fréquemment associées à des déficiences intellectuelles, des défauts qui empêchent les patients touchés d'avoir une vie normale et qui peux entrainer une mortalité précoce. Pour la plupart de ces conditions, seul un traitement symptomatique est disponible. Outre le diagnostic génétique, utile pour faire face à de nouvelles grossesses, une compréhens
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Ferraz, Lucio Fabio Caldas. "Investigação molecular do gene da 5 alfa redutase tipo 2 (SRD5A2) em pacientes com pseudohermaforditismo masculino (PHM)." [s.n.], 1999. http://repositorio.unicamp.br/jspui/handle/REPOSIP/316607.

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Orientador: Christine Hackel<br>Dissertação (mestrado) - Universidade Estadual de Campinas, Instituto de Biologia<br>Made available in DSpace on 2018-07-25T03:14:28Z (GMT). No. of bitstreams: 1 Ferraz_LucioFabioCaldas_M.pdf: 8458264 bytes, checksum: 1216d86d4eeffa6fa581b32e0511d502 (MD5) Previous issue date: 1999<br>Mestrado
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Neves, Adriana Freitas. "Variações transcricionais dos genes AR, SRD5A2, KLK2, PCA3, KLK3 e PSMA e implicações no diagnóstico molecular do câncer de próstata." Universidade Federal de Uberlândia, 2007. https://repositorio.ufu.br/handle/123456789/15771.

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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior<br>CHAPTER I - Prostate cancer is a common disease in the world and in some countries it is one of the main causes of male population mortality. Some molecular markers have been associated with prostate carcinogenesis. To observe changes in transcript levels of the AR, SRD5A2, KLK2, PSMA and PCA3 genes, the mRNA was analyzed in tissues with prostatic adenocarcinoma (PCa, N= 48) and benign prostatic hyperplasia (BPH, N= 25), performed through a differential multiplex RT-PCR assay. Significant differences were observed in the relative e
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Amorin, Bruna. "Polimorfismo V89L do gene 5 α-redutase tipo II (SRD5A2) e a associação com o risco de câncer de próstata :". reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2010. http://hdl.handle.net/10183/115564.

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Introdução: A pesquisa por marcadores genéticos de susceptibilidade a doenças geralmente focam um gene baseado nas propriedades e vias metabólicas de seus produtos protéicos, assim, genes envolvidos na biossíntese de andrógenos podem identificar possíveis alterações na carcinogênese prostática. Diferenças étnicas em polimorfismos apresentam um papel no metabolismo de hormônios e podem acometer diferentes raças no risco de desenvolver câncer de próstata. A 5 alfaredutase (SRD5A2) é a enzima responsável por catalisar irreversivelmente a conversão da testosterona no principal androgênio prostátic
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Lindström, Sara. "Genetic variation and prostate cancer : population-based association studies in Sweden." Doctoral thesis, Umeå universitet, Strålningsvetenskaper, 2007. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-1329.

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Prostate cancer constitutes the most common malignancy and the most common cause of cancer‐related death in Swedish men. A large body of evidence suggests that inherited genetic variants contribute to both development and progression of prostate cancer. The aim of this thesis is to identify genetic variants that alter prostate cancer risk and progression. All papers included in this thesis are based on a Swedish population‐based case‐control study (CAPS) comprising 2,965 incident prostate cancer cases and 1,823 controls. In paper I, we investigated if genetic variants in the E‐cadherin gene al
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Rang, Wei. "Emotional Movements Analysis and Classification with SRDA." OpenSIUC, 2017. https://opensiuc.lib.siu.edu/theses/2179.

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Motion databases are becoming larger with the development of hardware and software, applications based on these data have been widely used in many different areas, such as movies, animations, videos games, sports as well as computer vision and robotics. All those applications had made motion analysis and classification essential for better motion composition. However, in order to achieve a good connectivity between every motion and emotion behind it, it is totally important to understand human behavior, even if human movements are complex and hard to describe completely. In this thesis, we mak
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Dmitrienko, Alexandra [Verfasser], Michael [Akademischer Betreuer] Waidner, and Srdjan [Akademischer Betreuer] Capkun. "Security and privacy aspects of mobile platforms and applications / Alexandra Dmitrienko. Betreuer: Michael Waidner ; Srdjan Čapkun." Darmstadt : Universitäts- und Landesbibliothek Darmstadt, 2015. http://d-nb.info/111191026X/34.

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Ladenbauer, Josef [Verfasser], Klaus [Akademischer Betreuer] Obermayer, Viktor [Akademischer Betreuer] Jirsa, and Srdjan [Akademischer Betreuer] Ostojic. "The collective dynamics of adaptive neurons : insights from single cell and network models / Josef Ladenbauer. Betreuer: Klaus Obermayer. Gutachter: Viktor Jirsa ; Srdjan Ostojic." Berlin : Technische Universität Berlin, 2015. http://d-nb.info/1078310505/34.

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Livros sobre o assunto "SRD5A1"

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Jaroš, Peter. Samochod srdca. Agentúra Signum, 2008.

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Bunčák, Pavel. Jablko zo srdca. Slovenský spisovatel̕, 1985.

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Cabadaj, Peter. Pošlem domov srdca kúsok: Výber zo slovenskej exilovej poézie. Vyd. Matice slovenskej, 1997.

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Bednár, Roman. Kozmické melódie: Verše srdca a výpovede intelektu : kozmos po prvý raz vo veršoch. s.n., 1990.

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Daň srdca domovine: [súborné dielo]. Vydavatels̕tvo Michala Vaška, 2006.

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Poslem domov srdea kusok: vyber zo slovenskey exilovej poezie. 1997.

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Media, Irb. Summary of Srdja Popovic & Matthew Miller's Blueprint for Revolution. IRB MEDIA, 2022.

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Srda pjeva, u sumrak, na Duhove. Rende, 2009.

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Developments in Reliability Management (Reports: SRDA-R12). AEA Technology Plc, 1995.

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Brand, V. P. UPM 3.1: a Pragmatic Approach to Dependent Failures Assessment for Standard Systems (Reports: SRDA-R13). AEA Technology Plc, 1996.

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Capítulos de livros sobre o assunto "SRD5A1"

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Luthman, Anna Siri. "A Multispectral Endoscope Based on SRDAs." In Springer Theses. Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-98255-7_4.

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Tuysuz, Beyhan, Davut Pehlivan, Ahmet Özkök, et al. "Phenotypic Expansion of Congenital Disorder of Glycosylation Due to SRD5A3 Null Mutation." In JIMD Reports. Springer Berlin Heidelberg, 2015. http://dx.doi.org/10.1007/8904_2015_478.

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Huang, Jinjing, Lei Zhao, and Jiwen Yang. "SRDFA: A Kind of Session Reconstruction DFA." In Lecture Notes in Computer Science. Springer Berlin Heidelberg, 2008. http://dx.doi.org/10.1007/978-3-540-88140-7_5.

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Luthman, Anna Siri. "Wide-Field fHSI with a Linescan SRDA." In Springer Theses. Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-98255-7_3.

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Xu, Wenqiang, Yonglu Li, and Cewu Lu. "SRDA: Generating Instance Segmentation Annotation via Scanning, Reasoning and Domain Adaptation." In Computer Vision – ECCV 2018. Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-030-01258-8_8.

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Mariojouls, Catherine, and Sophie Girard. "Regional Schemes for the Development of Marine Aquaculture (SRDAM) and Access to New Farming Sites on the French Mediterranean Coast." In Evolution of Marine Coastal Ecosystems under the Pressure of Global Changes. Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-43484-7_30.

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Mak, Tak W., Josef Penninger, John Roder, Janet Rossant, and Mary Saunders. "Srd5a1." In The Gene Knockout FactsBook. Elsevier, 1998. http://dx.doi.org/10.1016/b978-012466044-1/50529-9.

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"Steroid 5-Beta Reductase (SRD5B1, 7q32-q33)." In Encyclopedia of Genetics, Genomics, Proteomics and Informatics. Springer Netherlands, 2008. http://dx.doi.org/10.1007/978-1-4020-6754-9_16180.

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Dhanarajalu, Susitra. "MNLR and ANFIS Based Inductance Profile Estimation for Switched Reluctance Motor." In Emerging Electric Machines - Advances, Perspectives and Applications [Working Title]. IntechOpen, 2021. http://dx.doi.org/10.5772/intechopen.96555.

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This chapter aims in presenting the methods for the accurate estimation of highly non linear phase inductance profile of a switched reluctance motor (SRM). The magnetization characteristics of a test SRM is derived from the SRDaS (Switched Reluctance Design and Simulation) simulation software. Statistical interpolation based regression analysis and Artificial Intelligence (AI) techniques are used for developing the computationally efficient inductance model. Multi Variate Non linear Regression (MVNLR) from the class of regression analysis and Adaptive Neuro Fuzzy Inference System (ANFIS) under
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Alzahrani, Ali S., Minjing Zou, Essa Baitei, Roua Al-Rijjal, Omalkhaire Al-Shaikh, and Yufei Shi. "An Acceptor Site Mutation in Intron 1 of the Steroid 5α-Reductase-2 (SRD5A2) Gene in Two Unrelated Cases of 46XY Male Pseudohermaphordite." In The Endocrine Society's 92nd Annual Meeting, June 19–22, 2010 - San Diego. Endocrine Society, 2010. http://dx.doi.org/10.1210/endo-meetings.2010.part1.p7.p1-311.

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Trabalhos de conferências sobre o assunto "SRD5A1"

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Luo, Qingling, Ming Chen, Xiangke Li, and Xiaohua Wu. "Modulation Optimization Design of Microinverter Based on SRDAB." In 2024 CPSS & IEEE International Symposium on Energy Storage and Conversion (ISESC). IEEE, 2024. https://doi.org/10.1109/isesc63657.2024.10785462.

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Макрецкая, Н. А., У. С. Нанзанова, И. Р. Хамаганова та ін. "Распространенность варианта p.E197K в гене SRD5A2 (RS534671822) среди бурят". У III Конференция по орфанным и детским эндокринным заболеваниям "Молекулярно-генетические исследования в практике детского эндокринолога". ФГБУ «НМИЦ эндокринологии» Минздрава России, 2023. http://dx.doi.org/10.14341/mgsppe-2023-60.

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Wang, Xizheng, Shuai Wang, and Dan Li. "sRDMA: A General and Low-Overhead Scheduler for RDMA." In APNET 2023: 7th Asia-Pacific Workshop on Networking. ACM, 2023. http://dx.doi.org/10.1145/3600061.3600082.

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Kuddus, Ruhul H., Asmahan A. El Ezzi, and Mohammed A. El-Saidi. "Abstract 5304: Association of prostate cancer and benign prostate hyperplasia with polymorphisms in VDR gene, CYP17 gene and SRD5A2 gene among Lebanese men." In Proceedings: AACR 104th Annual Meeting 2013; Apr 6-10, 2013; Washington, DC. American Association for Cancer Research, 2013. http://dx.doi.org/10.1158/1538-7445.am2013-5304.

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Li, Yufan, Fei Xiao, Jilong Liu, and Rui Zhou. "Reactive Power Minimization Modulation Strategy for NPC-SRDAB based on Particle Swarm Optimization." In 2024 IEEE 10th International Power Electronics and Motion Control Conference (IPEMC2024-ECCE Asia). IEEE, 2024. http://dx.doi.org/10.1109/ipemc-ecceasia60879.2024.10567450.

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6

Zhang, Weichen, Wen Li, and Dong Xu. "SRDAN: Scale-aware and Range-aware Domain Adaptation Network for Cross-dataset 3D Object Detection." In 2021 IEEE/CVF Conference on Computer Vision and Pattern Recognition (CVPR). IEEE, 2021. http://dx.doi.org/10.1109/cvpr46437.2021.00670.

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7

Hughes, Lucinda, Karen Ruth, and Veda N. Giri. "Abstract A9: Genetic polymorphisms in the vitamin D receptor gene and androgen pathway gene SRD5A2 may be informative of prostate cancer risk in African American men undergoing prostate cancer screening." In Abstracts: AACR International Conference on Frontiers in Cancer Prevention Research‐‐ Dec 6–9, 2009; Houston, TX. American Association for Cancer Research, 2010. http://dx.doi.org/10.1158/1940-6207.prev-09-a9.

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8

Hou, Jiang-Liang, and Ting-Gin Chen. "An RFID-Based Shopping Service System for Retailers." In ASME 2009 International Manufacturing Science and Engineering Conference. ASMEDC, 2009. http://dx.doi.org/10.1115/msec2009-84305.

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With the rapid development of global economy and great improvement on life quality of consumers, the consumer shopping behaviors have been changed significantly. Modern retailers have put intensive effort on merchandise arrangement in order to satisfy the consumer demands on merchandise shopping. However, most retailers do not provide satisfactory shopping services to customers. For instance, without a customized shopping recommendation for each individual customer, consumers have to spend a lot of time for merchandise selection. Furthermore, most large-spaced retailers merely utilize signs in
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9

Albuquerque, Ana Clara Berzoini, Júlia Berzoini Albuquerque, Vívian Maria De Oliveira Gomes, Débora Rodrigues Martins Martins, and Aripuanã Sakurada Aranha Watanabe. "A TEMPESTADE DE CITOCINAS NA COVID-19: UMA REVISÃO NARRATIVA." In I Congresso Brasileiro de Imunologia On-line. Revista Multidisciplinar em Saúde, 2021. http://dx.doi.org/10.51161/rems/964.

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Introdução: O vírus SARS-CoV-2 invade a célula hospedeira através da ligação entre a proteína viral SPIKE e o receptor ECA-2. A resposta antiviral ativa vias inflamatórias do sistema imune. Entretanto, uma resposta exacerbada com hiper-citocinemia pró-inflamatória, na chamada Tempestade de Citocinas (TC), pode evoluir com Síndrome do Desconforto Respiratório Agudo (SRDA) e falência múltipla dos órgãos. Objetivos: Analisar a relação entre a tempestade de citocinas na COVID-19 e a evolução da doença. Material e métodos: Realizou-se revisão narrativa com busca de artigos publicados entre 2020 e 2
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Relatórios de organizações sobre o assunto "SRD5A1"

1

Phipps, Troy J. SRD5A1 Genetic Variation and Prostate Cancer Epidemiology. Defense Technical Information Center, 2005. http://dx.doi.org/10.21236/ada441326.

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2

Phipps, Troy J. SRD5A1 Genetic Variation and Prostate Cancer Epidemiology. Defense Technical Information Center, 2004. http://dx.doi.org/10.21236/ada428280.

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