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Artigos de revistas sobre o tema "Stimulation corticale directe"

Autor: Grafiati

Publicado: 5 de outubro de 2024

Última modificação: 31 de julho de 2025

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1

Ahmed, Zaghloul, and Andrzej Wieraszko. "Trans-spinal direct current enhances corticospinal output and stimulation-evoked release of glutamate analog, D-2,3-3H-aspartic acid." Journal of Applied Physiology 112, no. 9 (2012): 1576–92. http://dx.doi.org/10.1152/japplphysiol.00967.2011.

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Trans-spinal direct current (tsDC) stimulation is a modulator of spinal excitability and can influence cortically elicited muscle contraction in a polarity-dependent fashion. When combined with low-frequency repetitive cortical stimulation, cathodal tsDC [tsDC(−)] produces a long-term facilitation of cortically elicited muscle actions. We investigated the ability of this combined stimulation paradigm to facilitate cortically elicited muscle actions in spinal cord-injured and noninjured animals. The effect of tsDC—applied alone or in combination with repetitive spinal stimulation (rSS) on the r

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Foster, Brett L., and Josef Parvizi. "Direct cortical stimulation of human posteromedial cortex." Neurology 88, no. 7 (2017): 685–91. http://dx.doi.org/10.1212/wnl.0000000000003607.

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Background:The posteromedial cortex (PMC) is a collective term for an anatomically heterogeneous area of the brain constituting a core node of the human default mode network (DMN), which is engaged during internally focused subjective cognition such as autobiographical memory.Methods:We explored the effects of causal perturbations of PMC with direct electric brain stimulation (EBS) during presurgical epilepsy monitoring with intracranial EEG electrodes.Results:Data were collected from 885 stimulations in 25 patients implanted with intracranial electrodes across the PMC. While EBS of regions im

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Lee, Hongju, Juyeon Lee, Dahee Jung, Harim Oh, Hwakyoung Shin, and Byungtae Choi. "Neuroprotection of Transcranial Cortical and Peripheral Somatosensory Electrical Stimulation by Modulating a Common Neuronal Death Pathway in Mice with Ischemic Stroke." International Journal of Molecular Sciences 25, no. 14 (2024): 7546. http://dx.doi.org/10.3390/ijms25147546.

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Therapeutic electrical stimulation, such as transcranial cortical stimulation and peripheral somatosensory stimulation, is used to improve motor function in patients with stroke. We hypothesized that these stimulations exert neuroprotective effects during the subacute phase of ischemic stroke by regulating novel common signaling pathways. Male C57BL/6J mouse models of ischemic stroke were treated with high-definition (HD)-transcranial alternating current stimulation (tACS; 20 Hz, 89.1 A/mm2), HD-transcranial direct current stimulation (tDCS; intensity, 55 A/mm2; charge density, 66,000 C/m2), o

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Adeel, Muhammad, Chun-Ching Chen, Bor-Shing Lin, et al. "Safety of Special Waveform of Transcranial Electrical Stimulation (TES): In Vivo Assessment." International Journal of Molecular Sciences 23, no. 12 (2022): 6850. http://dx.doi.org/10.3390/ijms23126850.

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Intermittent theta burst (iTBS) powered by direct current stimulation (DCS) can safely be applied transcranially to induce neuroplasticity in the human and animal brain cortex. tDCS-iTBS is a special waveform that is used by very few studies, and its safety needs to be confirmed. Therefore, we aimed to evaluate the safety of tDCS-iTBS in an animal model after brain stimulations for 1 h and 4 weeks. Thirty-one Sprague Dawley rats were divided into two groups: (1) short-term stimulation for 1 h/session (sham, low, and high) and (2) long-term for 30 min, 3 sessions/week for 4 weeks (sham and high

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Yaksh, Tony L., Jia-Yi Wang, V. L. W. Go, and Gail J. Harty. "Cortical Vasodilatation Produced by Vasoactive Intestinal Polypeptide (VIP) and by Physiological Stimuli in the Cat." Journal of Cerebral Blood Flow & Metabolism 7, no. 3 (1987): 315–26. http://dx.doi.org/10.1038/jcbfm.1987.69.

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In chloralose-urethanized cats, vasoactive intestinal peptide (VIP), applied by superfusion in steady-state concentration (10−10–10−6 M) onto cortical vessels in situ resulted in a rapid concentration-dependent vasodilatation in vessels that were mildly constricted by prostaglandin F2α (PGF2α) (5 × 10−5 M) or hypocarbia (PaCO2 = 26). The maximum dilatation produced by VIP (10−6 M) was about 60% over baseline in pial arteries and 40% in pial veins. Blockade of local neuronal activity with tetrodotoxin (TTX) (10−5 M) had no effect on the VIP-evoked dilation of pial vessels. Activation of the cor

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Moliadze, Vera, Georg Fritzsche, and Andrea Antal. "Comparing the Efficacy of Excitatory Transcranial Stimulation Methods Measuring Motor Evoked Potentials." Neural Plasticity 2014 (2014): 1–6. http://dx.doi.org/10.1155/2014/837141.

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The common aim of transcranial stimulation methods is the induction or alterations of cortical excitability in a controlled way. Significant effects of each individual stimulation method have been published; however, conclusive direct comparisons of many of these methods are rare. The aim of the present study was to compare the efficacy of three widely applied stimulation methods inducing excitability enhancement in the motor cortex: 1 mA anodal transcranial direct current stimulation (atDCS), intermittent theta burst stimulation (iTBS), and 1 mA transcranial random noise stimulation (tRNS) wi

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Huang, Yuhao (Danny), Sydney Cash, Corey Keller, and Angelique Paulk. "243 Intracranial Theta-burst Stimulation Modulates Cortical Excitability in a Dose and Location-dependent Fashion." Neurosurgery 70, Supplement_1 (2024): 67. http://dx.doi.org/10.1227/neu.0000000000002809_243.

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INTRODUCTION: Direct electrical stimulation is a powerful therapeutic approach to treating a wide range of brain disorders. In particular, theta-burst stimulation (TBS) which delivers electrical pulses in rhythmic bursts of 3-8 Hz to mimic endogenous brain rhythms, has been increasingly used to improve cognitive processes and relieve symptoms of depression. However, how TBS alters underlying neural activity is poorly understood. METHODS: In nine neurosurgical epilepsy subjects undergoing intracranial monitoring, we applied direct cortical TBS at varying stimulation amplitudes and locations (pr

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8

Maxian, Viorel. "DIRECT CORTICAL STIMULATION IN THE ABLATION OF GLIAL CEREBRAL TUMORS IN THE MOTOR AREAS." Arta Medica 76, no. 3 (2020): 71–75. https://doi.org/10.5281/zenodo.4070041.

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<strong>Objectives.</strong> The genesis of tumors is unknown in our days. Surgery represents an effective treatment of this disorder. According to many studies of brain tumor surgery, a motor deficit rate of 30% has been observed, postoperatively, after surgeries on brain tumors in the motor areas.  The aim of the study was to evaluate the direct cortical stimulation in the surgical treatment of glial brain tumors, in motor areas. <strong>Material and Methods. </strong>The examination group included 35 patients with brain tumors, localized in the parasilvian region. Direct cortical stimu

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9

Ahmed, Zaghloul. "Trans-spinal direct current stimulation modulates motor cortex-induced muscle contraction in mice." Journal of Applied Physiology 110, no. 5 (2011): 1414–24. http://dx.doi.org/10.1152/japplphysiol.01390.2010.

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The present study investigated the effect of trans-spinal direct current (tsDC) on the firing rate, pattern, and amplitude of spontaneous activity of the tibial nerve and on the magnitude of cortically elicited triceps surae (TS) muscle contractions. The effect of combined tsDC and repetitive cortical electrical stimulation (rCES) on the amplitude of cortically elicited TS twitches was also investigated. Stimulation was applied by two disk electrodes (0.79 cm2): one was located subcutaneously over the vertebral column (T10–L1) and was used to deliver anodal DC (a-tsDC) or cathodal DC (c-tsDC)

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D'Andola, Mattia, Massimiliano Giulioni, Vittorio Dante, Giudice Paolo Del, and Maria V. Sanchez-Vives. "Control of cortical oscillatory frequency by a closed-loop system." Journal of NeuroEngineering and Rehabilitation 16, no. 1 (2019): 7. https://doi.org/10.1186/s12984-018-0470-z.

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<strong>Background: </strong>We present a closed-loop system able to control the frequency of slow oscillations (SO) spontaneously generated by the cortical network in vitro. The frequency of SO can be controlled by direct current (DC) electric fields within a certain range. Here we set out to design a system that would be able to autonomously bring the emergent oscillatory activity to a target frequency determined by the experimenter.<strong>Methods: </strong>The cortical activity was recorded through an electrode and was analyzed online. Once a target frequency was set, the frequency of the

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Ip, Emily Y., Elisa Roncati Zanier, Amy H. Moore, Stefan M. Lee, and David A. Hovda. "Metabolic, Neurochemical, and Histologic Responses to Vibrissa Motor Cortex Stimulation after Traumatic Brain Injury." Journal of Cerebral Blood Flow & Metabolism 23, no. 8 (2003): 900–910. http://dx.doi.org/10.1097/01.wcb.0000076702.71231.f2.

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During the prolonged metabolic depression after traumatic brain injury (TBI), neurons are less able to respond metabolically to peripheral stimulation. Because this decreased responsiveness has been attributed to circuit dysfunction, the present study examined the metabolic, neurochemical, and histologic responses to direct cortical stimulation after lateral fluid percussion injury (LFPI). This study addressed three specific hypotheses: that neurons, if activated after LFPI, will increase their utilization of glucose even during a period of posttraumatic metabolic depression; that this seconda

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Qi, Xiaofei, Kexin Lyu, Long Meng, et al. "Low-Intensity Ultrasound Causes Direct Excitation of Auditory Cortical Neurons." Neural Plasticity 2021 (April 4, 2021): 1–10. http://dx.doi.org/10.1155/2021/8855055.

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Cochlear implantation is the first-line treatment for severe and profound hearing loss in children and adults. However, deaf patients with cochlear malformations or with cochlear nerve deficiencies are ineligible for cochlear implants. Meanwhile, the limited spatial selectivity and high risk of invasive craniotomy restrict the wide application of auditory brainstem implants. A noninvasive alternative strategy for safe and effective neuronal stimulation is urgently needed to address this issue. Because of its advantage in neural modulation over electrical stimulation, low-intensity ultrasound (

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Madsen, Jesper Guldsmed, Jakob Appel Østergaard, Henning Andersen, and Michael Pedersen. "Attenuation of Cortically Evoked Motor-Neuron Potential in Streptozotocin-Induced Diabetic Rats: A Study about the Effect of Diabetes upon Cortical-Initiated Movement." BioMed Research International 2020 (February 26, 2020): 1–5. http://dx.doi.org/10.1155/2020/1942534.

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Aims/Hypothesis. The complications affecting the peripheral nervous system, associated with diabetes mellitus, have been the focus of considerable research. Comparably less research has focused upon the effect of diabetes upon the central nervous system. In this study, we investigate the effect of diabetes upon motor-neuron potentials evoked in the motor cortex of streptozotocin diabetic rats. Methods. In this study, we investigated the cortical-evoked motor-neuron potentials in streptozotocin-induced diabetic rats. Cortical potentials were evoked using direct current stimulation to the motor

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Saleem, Yusra, Komal ., and Stephen Riaz. "Transcranial Direct Current Stimulation (TDCS)." International Journal of Endorsing Health Science Research (IJEHSR) 10, no. 4 (2022): 441–45. http://dx.doi.org/10.29052/ijehsr.v10.i4.2022.441-445.

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Transcranial direct current stimulation (TDCS) is a neuromodulatory device that is used for its ability to enhance cognitive and behavioral performance. Human studies suggest that TDCS modulates cortical excitability during stimulation by nonsynaptic changes of the cells, along with evidence that the after-effects of TDCS are driven by synaptic modification. TDCS represents a potential intervention to enhance cognition across clinical populations, including mild cognitive impairment among psychological and neurological disorders. Studies suggest that TDCS might be helpful in treating depressio

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Noll, Kyle, Priscella Asman, Katherine Connelly, et al. "NCOG-14. INTRAOPERATIVE COGNITIVE-LINGUISTIC MAPPING GUIDED BY VISUALIZATION OF GAMMA BAND MODULATION ELECTROCORTICOGRAMS: PROOF OF CONCEPT IN A PATIENT WITH LEFT TEMPORAL AND OCCIPITAL LOW-GRADE ASTROCYTOMA." Neuro-Oncology 24, Supplement_7 (2022): vii200. http://dx.doi.org/10.1093/neuonc/noac209.767.

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Abstract OBJECTIVE Determine the feasibility and preliminary utility of a novel approach to intraoperative brain mapping guided by visualization of electrocorticography (ECoG) heat maps. METHODS A 39-year-old male with a biopsy-proven left posterior temporal and occipital WHO grade II IDH-mutant astrocytoma underwent awake craniotomy with intraoperative language mapping. Language mapping utilized a dual iPad stimulus presentation system (NeuroMapper) coupled to a portable real-time neural signal processing system capable of both recording cortical activity and delivering direct cortical stimul

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Katakura, N., and S. H. Chandler. "An iontophoretic analysis of the pharmacologic mechanisms responsible for trigeminal motoneuronal discharge during masticatory-like activity in the guinea pig." Journal of Neurophysiology 63, no. 2 (1990): 356–69. http://dx.doi.org/10.1152/jn.1990.63.2.356.

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1. The effects of iontophoretic application of the excitatory amino acid antagonists kynurenic acid (KYN) and DL-2-amino-5-phosphonovaleric acid (APV), as well as the monoamines serotonin (5-HT) and norepinephrine (NE), on extracellularly recorded jaw opener motoneuron [digastric motoneuron (DIG)] discharge during cortically induced rhythmical masticatory-like activity (RMA) were examined in the anesthetized guinea pig. 2. Iontophoretic application of KYN, a broad-spectrum amino acid antagonist, suppressed the motoneuronal discharge evoked by short pulse train stimulation of the cortex for mos

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R.*, Rusina, Barek S., Vaculín S., Azerad J., and Rokyta R. "Cortical stimulation and tooth pulp evoked potentials in rats: A model of direct anti-nociception." Acta Neurobiologiae Experimentalis 70, no. 1 (2010): 47–55. http://dx.doi.org/10.55782/ane-2010-1773.

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While the effect of cortex stimulation on pain control is widely accepted, its physiological basis remains poorly understood. We chose an animal model of pain to study the influence of sensorimotor cortex stimulation on tooth pulp stimulation evoked potentials (TPEPs). Fifteen awake rats implanted with tooth pulp, cerebral cortex, and digastric muscle electrodes were divided into three groups, receiving 60 Hz, 40 Hz and no cortical stimulation, respectively. TPEPs were recorded before, one, three and five hours after continuous stimulation. We observed an inverse relationship between TPEP ampl

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Wong, Pei-Ling, Yea-Ru Yang, Shih-Fong Huang, and Ray-Yau Wang. "Effects of Transcranial Direct Current Stimulation Followed by Treadmill Training on Dual-Task Walking and Cortical Activity in Chronic Stroke: A Double-Blinded Randomized Controlled Trial." Journal of Rehabilitation Medicine 55 (March 21, 2023): jrm00379. http://dx.doi.org/10.2340/jrm.v55.5258.

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Objective: To explore the effects of transcranial direct current stimulation followed by treadmill training on dual-task gait performance and contralesional cortical activity in chronic stroke patients.Methods: Forty-five chronic stroke participants were randomized into 3 groups: a bilateral transcranial direct current stimulation and treadmill training group; a cathodal transcranial direct current stimulation and treadmill training group; and a sham transcranial direct current stimulation and treadmill training group for 50 min per session (20 min transcranial direct current stimulation follo

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Krings, Timo, Bradley R. Buchbinder, William E. Butler, et al. "Stereotactic Transcranial Magnetic Stimulation: Correlation with Direct Electrical Cortical Stimulation." Neurosurgery 41, no. 6 (1997): 1319–26. http://dx.doi.org/10.1097/00006123-199712000-00016.

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Schuh, Lori, and Ivo Drury. "Intraoperative electrocorticography and direct cortical electrical stimulation." Seminars in Anesthesia, Perioperative Medicine and Pain 16, no. 1 (1997): 46–55. http://dx.doi.org/10.1016/s0277-0326(97)80007-4.

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Oishi, M., K. Suzuki, O. Sasaki, et al. "Crossed aphasia elicited by direct cortical stimulation." Neurology 67, no. 7 (2006): 1306–7. http://dx.doi.org/10.1212/01.wnl.0000238468.84401.d4.

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Luders, H. O., I. Derakhshan, M. Oishi, et al. "CROSSED APHASIA ELICITED BY DIRECT CORTICAL STIMULATION." Neurology 68, no. 19 (2007): 1638–40. http://dx.doi.org/10.1212/01.wnl.0000265607.23814.05.

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Sehatpour, Pejman, Devin Adair, Stephanie Rohrig, et al. "Cortical Modulation using Transcranial Direct Current Stimulation." Brain Stimulation 7, no. 2 (2014): e4. http://dx.doi.org/10.1016/j.brs.2014.01.017.

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Sehatpour, Pejman, Devin Adair, Stephanie Rohrig, Joanna DiCostanzo, and Daniel C. Javitt. "Transcranial Direct Current Stimulation Modulates Cortical Networks." Brain Stimulation 10, no. 1 (2017): e7. http://dx.doi.org/10.1016/j.brs.2016.11.040.

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Taube, Wolfgang, Martin Schubert, Markus Gruber, Sandra Beck, Michael Faist, and Albert Gollhofer. "Direct corticospinal pathways contribute to neuromuscular control of perturbed stance." Journal of Applied Physiology 101, no. 2 (2006): 420–29. http://dx.doi.org/10.1152/japplphysiol.01447.2005.

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The antigravity soleus muscle (Sol) is crucial for compensation of stance perturbation. A corticospinal contribution to the compensatory response of the Sol is under debate. The present study assessed spinal, corticospinal, and cortical excitability at the peaks of short- (SLR), medium- (MLR), and long-latency responses (LLR) after posterior translation of the feet. Transcranial magnetic stimulation (TMS) and peripheral nerve stimulation were individually adjusted so that the peaks of either motor evoked potential (MEP) or H reflex coincided with peaks of SLR, MLR, and LLR, respectively. The i

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Rothwell, John. "Transcranial brain stimulation: Past and future." Brain and Neuroscience Advances 2 (January 2018): 239821281881807. http://dx.doi.org/10.1177/2398212818818070.

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This article provides a brief summary of the history of transcranial methods for stimulating the human brain in conscious volunteers and reviews the methodology and physiology of transcranial magnetic stimulation and transcranial direct current stimulation. The former stimulates neural axons and generates action potentials and synaptic activity, whereas the latter polarises the membrane potential of neurones and changes their sensitivity to ongoing synaptic inputs. When coupled with brain imaging methods such as functional magnetic resonance imaging or electroencephalography, transcranial magn

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Joshi, Rajat, Sainath Murali, and Nivethida Thirugnanasambandam. "Behavioral Validation of Individualized Low-Intensity Transcranial Electrical Stimulation (tES) Protocols." eneuro 10, no. 12 (2023): ENEURO.0374–22.2023. http://dx.doi.org/10.1523/eneuro.0374-22.2023.

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AbstractLarge interindividual variability in the effects of low-intensity transcranial electrical stimulation (tES) considerably limits its potential for clinical applications. It has been recently proposed that individualizing stimulation dose by accounting for interindividual anatomic differences would reduce the variability in electric fields (E-fields) over the targeted cortical site and therefore produce more consistent behavioral outcomes. However, improvement in behavioral outcomes following individualized dose tES has never been compared with that of conventional fixed dose tES. In thi

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Sehm, Bernhard, Alexander Schäfer, Judy Kipping, et al. "Dynamic modulation of intrinsic functional connectivity by transcranial direct current stimulation." Journal of Neurophysiology 108, no. 12 (2012): 3253–63. http://dx.doi.org/10.1152/jn.00606.2012.

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Transcranial direct current stimulation (tDCS) is a noninvasive brain stimulation technique capable of modulating cortical excitability and thereby influencing behavior and learning. Recent evidence suggests that bilateral tDCS over both primary sensorimotor cortices (SM1) yields more prominent effects on motor performance in both healthy subjects and chronic stroke patients than unilateral tDCS over SM1. To better characterize the underlying neural mechanisms of this effect, we aimed to explore changes in resting-state functional connectivity during both stimulation types. In a randomized sin

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Siever, Dave. "Stimulation Technologies: "New" Trends in "Old" Techniques." Biofeedback 43, no. 4 (2015): 180–92. http://dx.doi.org/10.5298/1081-5937-43.04.11.

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Optimal functioning of the brain and mind is essential for good mental health and well-being. Unfortunately, disruptions in specific brain region function may arise for a variety of reasons, which include adverse genetic predispositions, poor nutrition, illness and cerebral accidents, developmental hormonal shifts, and negative life events resulting in overload and stress reactions. Fortunately, there are low-cost, easy-to-use, and effective electronic brain-stimulating technologies available today. These stimulation technologies include audiovisual entrainment (AVE) devices (e.g., light and s

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Fregni, Felipe, Paulo S. Boggio, Marcelo C. Santos, et al. "Noninvasive cortical stimulation with transcranial direct current stimulation in Parkinson's disease." Movement Disorders 21, no. 10 (2006): 1693–702. http://dx.doi.org/10.1002/mds.21012.

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Kim, Paul E., and Manbir Singh. "Functional magnetic resonance imaging for brain mapping in neurosurgery." Neurosurgical Focus 15, no. 1 (2003): 1–7. http://dx.doi.org/10.3171/foc.2003.15.1.1.

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One of the most pertinent applications of the principle primum non nocere (first do no harm) is in the optimization of neurosurgical procedures for patients with resectable lesions. The gold standard for identifying eloquent areas of the brain to be avoided in resections is direct cortical stimulation and somatosensory evoked potential monitoring, which is itself an invasive, cumbersome and difficult technique for mapping these areas. Functional magnetic resonance imaging shows great promise as a viable noninvasive alternative to invasive mapping as well as significant current clinical utility

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Nitsche, M. A., S. Doemkes, T. Karaköse, et al. "Shaping the Effects of Transcranial Direct Current Stimulation of the Human Motor Cortex." Journal of Neurophysiology 97, no. 4 (2007): 3109–17. http://dx.doi.org/10.1152/jn.01312.2006.

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Transcranial DC stimulation (tDCS) induces stimulation polarity-dependent neuroplastic excitability shifts in the human brain. Because it accomplishes long-lasting effects and its application is simple, it is used increasingly. However, one drawback is its low focality, caused by 1) the large stimulation electrode and 2) the functionally effective reference electrode, which is also situated on the scalp. We aimed to increase the focality of tDCS, which might improve the interpretation of the functional effects of stimulation because it will restrict its effects to more clearly defined cortical

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Biella, Gerardo, Laura Uva, Ulrich G. Hofmann, and Marco De Curtis. "Associative Interactions Within the Superficial Layers of the Entorhinal Cortex of the Guinea Pig." Journal of Neurophysiology 88, no. 3 (2002): 1159–65. http://dx.doi.org/10.1152/jn.2002.88.3.1159.

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Associative fiber systems in the entorhinal cortex (EC) have been extensively studied in different mammals with tracing techniques. The largest contingent of intra-EC cortico-cortical fibers runs in the superficial layers and is distributed predominantly within longitudinal cortical bands. We studied the patterns of intrinsic EC connectivity in the in vitro isolated guinea pig brain preparation by performing current-source density analysis of field potential laminar profiles recorded with multi-channel silicon probes. The response pattern evoked by stimulation of the lateral olfactory tract wa

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Picht, Thomas, Sein Schmidt, Stephan Brandt, et al. "Preoperative Functional Mapping for Rolandic Brain Tumor Surgery: Comparison of Navigated Transcranial Magnetic Stimulation to Direct Cortical Stimulation." Neurosurgery 69, no. 3 (2011): 581–89. http://dx.doi.org/10.1227/neu.0b013e3182181b89.

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Abstract BACKGROUND: Transcranial magnetic stimulation (TMS) is the only noninvasive method for presurgical stimulation mapping of cortical function. Recent technical advancements have significantly increased the focality and usability of the method. OBJECTIVE: To compare the accuracy of a 3-dimensional magnetic resonance imaging-navigated TMS system (nTMS) with the gold standard of direct cortical stimulation (DCS). METHODS: The primary motor areas of 20 patients with rolandic tumors were mapped preoperatively with nTMS at 110% of the individual resting motor threshold. Intraoperative DCS was

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Biton, Victor, Miguel E. Fiol, John R. Gates, and Robert E. Maxwell. "Inhibitory Sensory Locus Defined by Direct Cortical Stimulation." Journal of Clinical Neurophysiology 5, no. 4 (1988): 338. http://dx.doi.org/10.1097/00004691-198810000-00040.

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Chadaide, Z., S. Arlt, A. Antal, MA Nitsche, N. Lang, and W. Paulus. "Transcranial Direct Current Stimulation Reveals Inhibitory Deficiency In Migraine." Cephalalgia 27, no. 7 (2007): 833–39. http://dx.doi.org/10.1111/j.1468-2982.2007.01337.x.

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The issue of interictal excitability of cortical neurons in migraine patients is controversial: some studies have reported hypo-, others hyperexcitability. The aim of the present study was to observe the dynamics of this basic interictal state by further modulating the excitability level of the visual cortex using transcranial direct current stimulation (tDCS) in migraineurs with and without aura. In healthy subjects anodal tDCS decreases, cathodal stimulation increases transcranial magnetic stimulation (TMS)-elicited phosphene thresholds (PT), which is suggested as a representative value of v

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Cherney, Leora R. "Cortical Stimulation and Aphasia: The State of the Science." Perspectives on Neurophysiology and Neurogenic Speech and Language Disorders 18, no. 1 (2008): 33–39. http://dx.doi.org/10.1044/nnsld18.1.33.

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Abstract Purpose: Biological approaches to aphasia rehabilitation involve procedures aimed to alter brain anatomy and physiology so that language function can be restored. One such approach is the application of electrical stimulation to the cerebral cortex to facilitate brain plasticity and enhance stroke recovery. Method: This article discusses the rationale for the application of cortical stimulation and reviews three different methods of delivering cortical brain stimulation — repetitive transcranial magnetic stimulation (rTMS), transcranial direct current stimulation (tDCS), and epidural

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Henseler, Ilona, Andreas Mädebach, Sonja A. Kotz, and Jörg D. Jescheniak. "Modulating Brain Mechanisms Resolving Lexico-semantic Interference during Word Production: A Transcranial Direct Current Stimulation Study." Journal of Cognitive Neuroscience 26, no. 7 (2014): 1403–17. http://dx.doi.org/10.1162/jocn_a_00572.

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The aim of the current study was to shed further light on control processes that shape semantic access and selection during speech production. These processes have been linked to differential cortical activation in the left inferior frontal gyrus (IFG) and the left middle temporal gyrus (MTG); however, the particular function of these regions is not yet completely elucidated. We applied transcranial direct current stimulation to the left IFG and the left MTG (or sham stimulation) while participants named pictures in the presence of associatively related, categorically related, or unrelated dis

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Cohen, L. G., S. Sato, K. Kufta, and M. Hallett. "Attenuation of somatosensory perception by transcranial magnetic stimulation and direct cortical stimulation." Electroencephalography and Clinical Neurophysiology 75 (January 1990): S25—S26. http://dx.doi.org/10.1016/0013-4694(90)91809-4.

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Oda, Nobuhito, Masami Ishii, and Bong-Kyun Kim. "The efficacy of direct motor cortical stimulation for sensori-motor cortical lesions." Clinical Neurology and Neurosurgery 99 (July 1997): S33. http://dx.doi.org/10.1016/s0303-8467(97)81392-3.

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Nitsche, Michael A., Astrid Schauenburg, Nicolas Lang, et al. "Facilitation of Implicit Motor Learning by Weak Transcranial Direct Current Stimulation of the Primary Motor Cortex in the Human." Journal of Cognitive Neuroscience 15, no. 4 (2003): 619–26. http://dx.doi.org/10.1162/089892903321662994.

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Transcranially applied weak direct currents are capable of modulating motor cortical excitability in the human. Anodal stimulation enhances excitability, cathodal stimulation diminishes it. Cortical excitability changes accompany motor learning. Here we show that weak direct currents are capable of improving implicit motor learning in the human. During performance of a serial reaction time task, the primary motor cortex, premotor, or prefrontal cortices were stimulated contralaterally to the performing hand. Anodal stimulation of the primary motor cortex resulted in increased performance, wher

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Ille, Sebastian, Nico Sollmann, Theresa Hauck, et al. "Combined noninvasive language mapping by navigated transcranial magnetic stimulation and functional MRI and its comparison with direct cortical stimulation." Journal of Neurosurgery 123, no. 1 (2015): 212–25. http://dx.doi.org/10.3171/2014.9.jns14929.

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OBJECT Repetitive navigated transcranial magnetic stimulation (rTMS) is now increasingly used for preoperative language mapping in patients with lesions in language-related areas of the brain. Yet its correlation with intraoperative direct cortical stimulation (DCS) has to be improved. To increase rTMS's specificity and positive predictive value, the authors aim to provide thresholds for rTMS's positive language areas. Moreover, they propose a protocol for combining rTMS with functional MRI (fMRI) to combine the strength of both methods. METHODS The authors performed multimodal language mappin

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Baeken, C. "tDCS home based treatment following accelerated dTMS in the elderly depressed." European Psychiatry 66, S1 (2023): S45—S46. http://dx.doi.org/10.1192/j.eurpsy.2023.167.

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AbstractWith a growing number of elderly persons, geriatric depression - associated with important morbidity and mortality- is becoming a significant health problem. Given the risk of polypharmacy and increased side effects, alternative non pharmaceutical treatments such as repetitive transcranial magnetic stimulation (rTMS) and transcranial direct current stimulation (tDCS) may be solution. Recently, the FDA approved deep brain TMS (dTMS) for depression, not only stimulating deeper cortical areas but response and remission rates may be better, especially in elderly populations. Nevertheless,

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Gomez-Tames, Jose, Akimasa Hirata, Manabu Tamura, and Yoshihiro Muragaki. "Corticomotoneuronal Model for Intraoperative Neurophysiological Monitoring During Direct Brain Stimulation." International Journal of Neural Systems 29, no. 01 (2019): 1850026. http://dx.doi.org/10.1142/s0129065718500260.

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Intraoperative neurophysiological monitoring during brain surgery uses direct cortical stimulation to map the motor cortex by recording muscle activity induced by the excitation of alpha motor neurons (MNs). Computational models have been used to understand local brain stimulation. However, a computational model revealing the stimulation process from the cortex to MNs has not yet been proposed. Thus, the aim of the current study was to develop a corticomotoneuronal (CMN) model to investigate intraoperative stimulation during surgery. The CMN combined the following three processes into one syst

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Picht, Thomas, Sven Mularski, Bjoern Kuehn, Peter Vajkoczy, Theodoros Kombos, and Olaf Suess. "Navigated Transcranial Magnetic Stimulation for Preoperative Functional Diagnostics in Brain Tumor Surgery." Operative Neurosurgery 65, suppl_6 (2009): ons93—ons99. http://dx.doi.org/10.1227/01.neu.0000348009.22750.59.

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Abstract Objective: Transcranial magnetic stimulation (TMS) is a noninvasive method for analyzing cortical function. To utilize TMS for presurgical functional diagnostics, the magnetic impulse must be precisely targeted by stereotactically positioning the coil. The aim of this study was to evaluate the usefulness of TMS for operation planning when combined with a sensor-based electromagnetic navigation system (nTMS). Methods: Preoperative functional mapping with nTMS was performed in 10 patients with rolandic tumors. Intraoperative mapping was performed with the “gold standard” of direct corti

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Jefferson, Samantha, Satish Mistry, Salil Singh, John Rothwell, and Shaheen Hamdy. "Characterizing the application of transcranial direct current stimulation in human pharyngeal motor cortex." American Journal of Physiology-Gastrointestinal and Liver Physiology 297, no. 6 (2009): G1035—G1040. http://dx.doi.org/10.1152/ajpgi.00294.2009.

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Transcranial direct current stimulation (tDCS) is a novel intervention that can modulate brain excitability in health and disease; however, little is known about its effects on bilaterally innervated systems such as pharyngeal motor cortex. Here, we assess the effects of differing doses of tDCS on the physiology of healthy human pharyngeal motor cortex as a prelude to designing a therapeutic intervention in dysphagic patients. Healthy subjects ( n = 17) underwent seven regimens of tDCS (anodal 10 min 1 mA, cathodal 10 min 1 mA, anodal 10 min 1.5 mA, cathodal 10 min 1.5 mA, anodal 20 min 1 mA,

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Lim, Sung Hyuk, and Min Hwan Jang. "Technical Considerations of Effective Direct Cortical and Subcortical Stimulation." Korean Journal of Clinical Laboratory Science 54, no. 2 (2022): 157–62. http://dx.doi.org/10.15324/kjcls.2022.54.2.157.

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Bialik, Paul Shkurovich. "38. Mapping eloquent cortical areas with direct electrical stimulation." Clinical Neurophysiology 127, no. 9 (2016): e311. http://dx.doi.org/10.1016/j.clinph.2016.05.313.

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Speth, C., J. Speth, and T. Harley. "Transcranial direct current stimulation and cortical indicators of relaxation." Brain Stimulation 8, no. 2 (2015): 405. http://dx.doi.org/10.1016/j.brs.2015.01.290.

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Sun, Yan, Sameer C. Dhamne, Alejandro Carretero‐Guillén, et al. "Drug‐Responsive Inhomogeneous Cortical Modulation by Direct Current Stimulation." Annals of Neurology 88, no. 3 (2020): 489–502. http://dx.doi.org/10.1002/ana.25822.

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