Bibliografias temáticas / Structural virology

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Literatura científica selecionada sobre o tema "Structural virology"

Autor: Grafiati

Publicado: 14 de dezembro de 2024

Última modificação: 31 de julho de 2025

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Artigos de revistas sobre o assunto "Structural virology"

Agbandje-McKenna, Mavis, and Richard Kuhn. "Current opinion in virology: structural virology." Current Opinion in Virology 1, no. 2 (2011): 81–83. http://dx.doi.org/10.1016/j.coviro.2011.07.001.

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Stuart, David. "Changing times in structural virology." Acta Crystallographica Section A Foundations and Advances 75, a2 (2019): e18-e18. http://dx.doi.org/10.1107/s205327331909538x.

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Sousa, Rui. "Structural Virology 4. T7 RNA Polymerase." Uirusu 51, no. 1 (2001): 81–94. http://dx.doi.org/10.2222/jsv.51.81.

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Shepherd, C. M. "VIPERdb: a relational database for structural virology." Nucleic Acids Research 34, no. 90001 (2006): D386—D389. http://dx.doi.org/10.1093/nar/gkj032.

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Kiss, Bálint, Dorottya Mudra, György Török, et al. "Single-particle virology." Biophysical Reviews 12, no. 5 (2020): 1141–54. http://dx.doi.org/10.1007/s12551-020-00747-9.

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Abstract The development of advanced experimental methodologies, such as optical tweezers, scanning-probe and super-resolved optical microscopies, has led to the evolution of single-molecule biophysics, a field of science that allows direct access to the mechanistic detail of biomolecular structure and function. The extension of single-molecule methods to the investigation of particles such as viruses permits unprecedented insights into the behavior of supramolecular assemblies. Here we address the scope of viral exploration at the level of individual particles. In an era of increased awarenes

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Meier, Kristina, Sigurdur R. Thorkelsson, Emmanuelle R. J. Quemin, and Maria Rosenthal. "Hantavirus Replication Cycle—An Updated Structural Virology Perspective." Viruses 13, no. 8 (2021): 1561. http://dx.doi.org/10.3390/v13081561.

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Hantaviruses infect a wide range of hosts including insectivores and rodents and can also cause zoonotic infections in humans, which can lead to severe disease with possible fatal outcomes. Hantavirus outbreaks are usually linked to the population dynamics of the host animals and their habitats being in close proximity to humans, which is becoming increasingly important in a globalized world. Currently there is neither an approved vaccine nor a specific and effective antiviral treatment available for use in humans. Hantaviruses belong to the order Bunyavirales with a tri-segmented negative-sen

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Rossmann, Michael G. "Virus crystallography and structural virology: a personal perspective." Crystallography Reviews 21, no. 1-2 (2014): 57–102. http://dx.doi.org/10.1080/0889311x.2014.957282.

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Khayat, Reza. "Call for Papers: Special Issue on Structural Virology." Viral Immunology 32, no. 10 (2019): 415. http://dx.doi.org/10.1089/vim.2019.29046.cfp.

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Schoehn, Guy, Florian Chenavier, and Thibaut Crépin. "Advances in Structural Virology via Cryo-EM in 2022." Viruses 15, no. 6 (2023): 1315. http://dx.doi.org/10.3390/v15061315.

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Handa, Tanuj, Ankita Saha, Aarthi Narayanan, et al. "Structural Virology: The Key Determinants in Development of Antiviral Therapeutics." Viruses 17, no. 3 (2025): 417. https://doi.org/10.3390/v17030417.

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Structural virology has emerged as the foundation for the development of effective antiviral therapeutics. It is pivotal in providing crucial insights into the three-dimensional frame of viruses and viral proteins at atomic-level or near-atomic-level resolution. Structure-based assessment of viral components, including capsids, envelope proteins, replication machinery, and host interaction interfaces, is instrumental in unraveling the multiplex mechanisms of viral infection, replication, and pathogenesis. The structural elucidation of viral enzymes, including proteases, polymerases, and integr

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Teses / dissertações sobre o assunto "Structural virology"

Sabaratnam, Keshalini. "The interaction between the Marek's Disease Virus (MDV) neurovirulence factor pp14 and the host transcription factor, CREB3." Thesis, University of Oxford, 2017. http://ora.ox.ac.uk/objects/uuid:d2fc6bd4-bc3a-4a37-924b-86881096a9b5.

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Marek's Disease Virus (MDV) induces a wide range of neurological syndromes in susceptible hosts; however, the mechanisms behind the MDV-induced neuropathology are still poorly understood. The immediate-early 14kDa phosphoprotein, pp14, is associated with the neurovirulence phenotype of the virus. Yeast-two-hybrid screening identified the ER-bound transcription regulator, human CREB3 (cAMP Response Element-Binding protein), as an interacting partner of pp14, and fluorescence colocalisation between pp14 and chicken CREB3 (chCREB3) in MDV infected cells suggested an interaction between these prot

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Conley, Michaela Jayne. "Structural and functional characterisation of feline calicivirus entry." Thesis, University of Glasgow, 2018. http://theses.gla.ac.uk/8920/.

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The Caliciviridae are a group of small, non-enveloped viruses with a positive sense, single stranded RNA genome. Caliciviruses include the noroviruses, responsible for winter vomiting disease, as well as several important veterinary pathogens. Feline calicivirus (FCV) is an excellent model for studying calicivirus entry, having a known protein receptor and being readily propagated in cell culture. Here we explore calicivirus entry, using FCV. Virus entry is the critical first step of infection and is therefore an important area of study. Both alpha 2-6 linked sialic acid and feline junctional

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Thompson, Catherine Isabelle. "Protein interaction studies on the rotavirus non-structural protein NSP1." Thesis, University of Warwick, 1999. http://wrap.warwick.ac.uk/80266/.

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Rotavirus encodes six structural and six non-structural proteins. In contrast to the structural proteins, the functional roles of the non-structural proteins are not well defined beyond a realisation that they must have a role in the viral replication cycle. A fuller understanding of the replication cycle must therefore rest on determining the specific roles played by the non-structural proteins. Non-structural protein NSP1 shows high levels of sequence divergence. A generally well conserved cysteine-rich region at the amino-terminus may form a zinc finger structure. It has been shown to posse

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Rezelj, Veronica Valentina. "Characterization of the non-structural (NSs) protein of tick-borne phleboviruses." Thesis, University of Glasgow, 2017. http://theses.gla.ac.uk/8149/.

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In recent years, a number of newly discovered tick-borne viruses exhibiting a wide spectrum of diseases in humans have been ascribed to the Phlebovirus genus of the Bunyaviridae family. These viruses have a tripartite RNA genome composed of two negative-sense RNA segments (medium and large) and one ambisense segment (small), which encode four structural proteins and one non-structural protein (NSs). The NSs protein is the major virulence factor of bunyaviruses, and acts as an antagonist of a key component of the first line of defence against viral infections: the interferon (IFN) system (Bridg

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Howard, Susan Teresa. "Structural and functional analyses on the SalI G fragment of vaccinia virus." Thesis, University of Cambridge, 1991. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.386088.

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Martin, Morgan Mackensie. "Functional analysis of hepatitis C virus non-structural protein (NS) 3 protease and viral cofactor NS4A." Thesis, University of British Columbia, 2008. http://hdl.handle.net/2429/1522.

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The hepatitis C virus (HCV) was identified in 1989 as the major causative agent of transfusion-associated non-A, non-B hepatitis and today represents a worldwide health crisis with prevalence estimates of 2.2%. HCV-specific therapeutics have never been more urgently needed. One of the validated drug targets is the non-structural (NS) protein 3 (NS3) membrane-bound protease. The major aim of this thesis was characterization of NS3 allosteric activation by its viral cofactor, NS4A. We hypothesized that there would be specific residues that dominate the interaction between NS3 and NS4A, and furth

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Lauder, Rebecca Pink. "Structural analysis of adenovirus bound to blood coagulation factors that influence viral tropism." Thesis, University of Glasgow, 2011. http://theses.gla.ac.uk/2636/.

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Adenoviruses are currently the most commonly used vectors for clinical gene therapy trials. Of these, Ad5 is the most commonly used serotype. Upon intravenous delivery, the vectors are sequestered in the liver which reduces their efficacy. While the coxsackievirus and adenovirus receptor is responsible for in vitro cell entry, this pathway is not used in vivo. Blood coagulation factors have been implicated in mediating in vivo hepatic transduction, and it is therefore important to characterise the interaction between these and Ad5 in order to permit development of more efficacious and safer vi

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Leigh, Kendra Elizabeth. "Structural Studies of a Subunit of the Murine Cytomegalovirus Nuclear Egress Complex." Thesis, Harvard University, 2015. http://nrs.harvard.edu/urn-3:HUL.InstRepos:14226065.

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The Herpesviridae family of viruses includes a number of human pathogens of clinical importance. Like other herpesviruses, cytomegaloviruses require a heterodimeric nuclear egress complex (NEC) consisting of a membrane-bound protein and a soluble nucleoplasmic protein, termed in murine cytomegalovirus (MCMV) M50 and M53, respectively. Genetic, electron microscopic, and immunocytochemical studies have revealed the importance of this complex for viral replication, most predominantly in facilitating egress of viral nucleocapsids across the nuclear membrane. Despite the significance of the NEC to

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Ruiz, Arroyo Víctor Manuel. "Structural and functional analysis of Zika Virus NS5 protein." Doctoral thesis, Universitat de Barcelona, 2020. http://hdl.handle.net/10803/671922.

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Zika virus (ZIKV) belongs to the Flaviviridae family and constitute an important public health concern since ZIKV infection produced devastating effects in new born infants. Flaviviruses present a positive sense single stranded RNA genome flanked by highly structured untranslated regions (UTR) carrying one open reading frame that codifies for three structural proteins (C, prM, E) and five nonstructural proteins (NS1-5). At the most C-terminal end, NS5 protein carries a RNA dependent RNA polymerase (RdRP) and a methyl transferase domain (MTase) for genome copying and 5’ capping activities of th

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Rainsford, Edward. "Functional studies on the rotavirus non-structural proteins NSP5 and NSP6." Thesis, University of Warwick, 2005. http://wrap.warwick.ac.uk/53876/.

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The rotavirus replication cycle has not been fully characterised, one vital stage of virus replication involves large cytoplasmic occlusion bodies termed viroplasms. These are the sites of synthesis and replication of dsRNA, packaging of viral RNA into newly synthesized cores and the formation of double-shelled previrions. The detailed mechanism by which these events occur is poorly understood but is thought to be mediated by the non-structural proteins localised to these structures. Rotavirus gene segment 11 expresses two proteins NSP5 and NSP6 which are found in alternate open reading frames

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Livros sobre o assunto "Structural virology"

Agbandje-McKenna, Mavis, and Robert McKenna, eds. Structural Virology. Royal Society of Chemistry, 2010. http://dx.doi.org/10.1039/9781849732239.

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Agbandje-McKenna, Mavis, and McKenna Robert. Structural virology. RSC Publishing, 2011.

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Uversky, Vladimir N. Flexible viruses: Structural disorder in viral proteins. Wiley, 2012.

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J, Gibbs A., Calisher Charles H, and Garcia-Arenal Fernando, eds. Molecular basis of virus evolution. Cambridge University Press, 1995.

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Wah, Chiu, Burnett Roger M, and Garcea Robert L, eds. Structural biology of viruses. Oxford University Press, 1997.

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Kasteel, Daniella T. J. Structure, morphogenesis and function of tubular structures induced by cowpea mosaic virus. [s.n.], 1999.

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McKenna, Robert, Stephen Neidle, David M. J. Lilley, Mavis Agbandje-McKenna, and Roderick E. Hubbard. Structural Virology. Royal Society of Chemistry, The, 2010.

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Longhi, Sonia, and Vladimir Uversky. Flexible Viruses: Structural Disorder in Viral Proteins. Wiley & Sons, Incorporated, John, 2011.

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Longhi, Sonia, and Vladimir Uversky. Flexible Viruses: Structural Disorder in Viral Proteins. Wiley & Sons, Incorporated, John, 2011.

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Longhi, Sonia, and Vladimir Uversky. Flexible Viruses: Structural Disorder in Viral Proteins. Wiley & Sons, Incorporated, John, 2011.

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Capítulos de livros sobre o assunto "Structural virology"

Azad, Kimi, Debajit Dey, and Manidipa Banerjee. "Structural Alterations in Non-enveloped Viruses During Disassembly." In Physical Virology. Springer International Publishing, 2023. http://dx.doi.org/10.1007/978-3-031-36815-8_9.

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Schmidt, I., D. Ebner, M. A. Skinner, M. Pfleiderer, B. Schelle-Prinz, and S. G. Siddell. "Structural Proteins of the Murine Coronavirus MHV-JHM." In Modern Trends in Virology. Springer Berlin Heidelberg, 1988. http://dx.doi.org/10.1007/978-3-642-73745-9_9.

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Bakshi, Arindam, G. P. Vishnu Vardhan, M. Hema, M. R. N. Murthy, and H. S. Savithri. "Structural and Functional Characterization of Sesbania Mosaic Virus." In A Century of Plant Virology in India. Springer Singapore, 2017. http://dx.doi.org/10.1007/978-981-10-5672-7_18.

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Ponnusamy, Nirmaladevi, Nakul Ravi, Tamilbharathi Palanisamy, Faraz Ahmad, and Mohanapriya Arumugam. "Reverse and Structural Viral and Bacterial Vaccine Design." In Global Virology V: 21st Century Vaccines and Viruses. Springer Nature Switzerland, 2025. https://doi.org/10.1007/978-3-031-77911-4_7.

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Dhamodharan, Pavithra, Tamil Barathi Palanisamy, Pandjassarame Kangueane, and Mohanapriya Arumugam. "Human Metapneumovirus: Putative Roles of Structural Proteins and Need for Vaccine." In Global Virology V: 21st Century Vaccines and Viruses. Springer Nature Switzerland, 2025. https://doi.org/10.1007/978-3-031-77911-4_6.

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Fabian, Marc R., and K. Andrew White. "Solution Structure Probing of RNA Structures." In Plant Virology Protocols. Humana Press, 2008. http://dx.doi.org/10.1007/978-1-59745-102-4_17.

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McGarvey, Michael J., and Michael Houghton. "Structure and Molecular Virology." In Viral Hepatitis. John Wiley & Sons, Ltd, 2013. http://dx.doi.org/10.1002/9781118637272.ch16.

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Negro, Francesco. "Structure and Molecular Virology." In Viral Hepatitis. John Wiley & Sons, Ltd, 2013. http://dx.doi.org/10.1002/9781118637272.ch27.

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Meng, Xiang-Jin. "Structure and Molecular Virology." In Viral Hepatitis. John Wiley & Sons, Ltd, 2013. http://dx.doi.org/10.1002/9781118637272.ch30.

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Luangsay, Souphalone, and Fabien Zoulim. "Structure and Molecular Virology." In Viral Hepatitis. John Wiley & Sons, Ltd, 2013. http://dx.doi.org/10.1002/9781118637272.ch5.

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Trabalhos de conferências sobre o assunto "Structural virology"

Lee, Junghoon, Peter C. Doerschuk, and John E. Johnson. "Simultaneous 3-D Image Reconstruction and Classication with Applications to Structural Virology*." In Signal Recovery and Synthesis. OSA, 2007. http://dx.doi.org/10.1364/srs.2007.ptua1.

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Khalid MOHAMMED, Ansam, Nazih Wayes ZAID, and Mariam Hamdi ABDULKAREEM. "SECTION OF VETERINARY MEDICINE: MICROBIOLOGY, IMMUNITY AND VIROLOGY. THE BACTERIAL CONTAMINATION WITH PROTEUS AND E. COLI IN CERVIX AND UTERINE OF COWS DURING THE DIFFERENT ESTRUS PHASES." In VIII.International ScientificCongressofPure,AppliedandTechnological Sciences. Rimar Academy, 2023. http://dx.doi.org/10.47832/minarcongress8-15.

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The herein research was carried out in order to identified the presence of bacteria in cervix and uterine lumen in Iraqi cattle during the different estrus phase with focusing on Protus and E coli. Estrus phases were determined by the structures which found on ovary (follicular growth for pro-estrus, mature growing follicle for estrus, hemorrhagic corpus luteam for meta-estrus and active corpus luteam for di-eatrus). Forty cervical swabs (ten for each estrus phase) and forty uterine swabs (ten for each estrus phase) were taken from macroscopically healthy reproductive animals after slaughterin

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