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Englund, Jonas. "Another Student´s T-test : Proposal and evaluation of a modified T-test." Thesis, Örebro universitet, Handelshögskolan vid Örebro Universitet, 2014. http://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-37501.
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Starke, Ingo. "Der zweistufige Zwei-Stichproben-t-Test mit minimalem ASN-Maximum /." Berlin : Logos-Verl, 2009. http://d-nb.info/996600647/04.
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Ellims, Michael. "The Effectiveness of t-way Test Data Generation." Thesis, Open University, 2009. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.518201.
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Guédon, Dominique. "Le M. F. F. T. : un test exécutif ?" Rouen, 2003. http://www.theses.fr/2003ROUEL463.
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Pour tenter de répondre à cette interrogation, la thèse se place dans le cadre général de la psychométrie cognitive. L'hypothèse générale est que la tâche à réaliser dans le MFFT, qui impose un ajustement vitesse-précision "spontané", met en jeu des processus de contrôle et de régulation généraux dont la connaissance théorique et l'évaluation individuelle dans une éventuelle visée diagnostique sont des enjeux d'interêt. Ces processus renvoyant, dans la littérature, aux fonctions et aux processus exécutifs, nous avons adopté cette perspective au travers d'épreuves d'inhibition et de flexibilité complétées par une approche en termes de capacités(de mémoire de travail) et de vitesse de traitement. Quatre études, menées avec un total de 299 enfants de 10 ans, indiquent que le compromis vitesse-précision relève de processus adaptatifs généraux et précisent l'implication de la mémoire de travail et, à un moindre degré, de la flexibilité dans ce compromis<br>To try to answer this interrogation, the dissertation is placed within the general framework of the cognitive psychometry. The general assumption is that the task to be realized in the MFFT, which imposes a "spontaneous" speed-accuracy trade-off, involves general processes of control and regulation whose theoretical knowledge and individual evaluation in a possible diagnostic aim are interesting aspects. These processes implying, according to the literature, the executive functions and processes, we adopted this executive perspective through tests of inhibition and flexibility completed by an approach in terms of capacities (of working memory) and of speed of information processing. Four studies, undertaken with a total of 299 10-year-old children, indicate that the speed-accuracy trade-off concerns general adaptive processes, and clarify the implication of the working memory and, with a less degree, of the flexibility in this trade-off
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Andrade, Rodrigo Maciel. "Relação entre parâmetros biomecânicos e a aceleração no basquetebol." Universidade de São Paulo, 2009. http://www.teses.usp.br/teses/disponiveis/39/39132/tde-01022010-102903/.
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O objetivo do estudo foi investigar o construto da tarefa de múltiplas acelerações a partir de parâmetros biomecânicos de saltos verticais. 19 jogadoras da seleção brasileira adulta de basquetebol feminino realizaram o teste de múltiplas acelerações (teste T), salto vertical com contramovimento (SV) e salto vertical com contramovimento precedido de corrida (SVcorrida). Os parâmetros biomecânicos do SV foram, tempo de fase concêntrica (Tcon), pico de força de propulsão (PFP), tempo decorrido entre início da fase concêntrica e o pico de força de propulsão (TPFP), taxa de desenvolvimento de força (TDF) e impulso (I); para SVcorrida, velocidade média de aproximação (Velmédia), tempo total do movimento (Ttotal), pico de força passiva (PFPa), tempo decorrido entre início da fase de apoio e pico de força passiva (TPFPa), pico de força de propulsão (PFP), tempo decorrido entre início da fase de apoio e pico de força de propulsão (TPFPp), Load Rate (LR) e taxa de desenvolvimento de força (TDF). Para análise dos dados, inicialmente, recorreu-se a análise de componentes principais, revelando que 61,3% da variância total do SV foi explicada pelo componente predominantemente temporal (Tcon, TPFP e PFP) e 20,7% pelo componente predominantemente cinético (I e TDF); para SVcorrida, 58,7% da variância total foi explicada pelo componente predominantemente temporal (Ttotal, TPFPa, TPFPp, LR e TDF), 15,4% pelo componente predominantemente cinético (PFPa e PFP) e 12,8% pelo componente velocidade (Velmédia). Adicionalmente, foram reveladas correlações significantes de 0,55 (Tcon), -0,54 (Velmédia) e -0,49 (PFP) com o teste T, evidenciando um construto determinado pela capacidade de se gerar elevada força na fase concêntrica, reduzir o tempo de fase concêntrica e se aproximar do ponto de mudança de direção com elevada velocidade.<br>The main aim of the study was to investigate the multiple-acceleration task construct from vertical jumps biomechanics parameters. Nineteen female basketball players from Brazilian national team performed the multiple-acceleration test (T test), countermovement jump (VJ) and countermovement jump preceded by run (VJr). The VJ biomechanics parameters observed were: concentric phase duration (CPD), propulsion peak force (PPF), time to reach propulsion peak force (TPPF), rate of force development (RFD) and impulse (I); for VJr the parameters were mean velocity (MV), movement total duration (MTD), passive peak force (PaPF), time to reach passive peak force (TPaPF), propulsion peak force (PPF), time to reach propulsion peak force (TPpPF), load rate (LR) and rate of force development (RFD). Data were first analyzed by principal component analysis. The results showed that 61.3% of VJ variance could be explained by time factor (CPD, TPPF and PPF), and 20.7% by kinetic factor (I and RFD). To VJr, 58.7% of total variance could be explained by time factor (MTD, TPaPF, TPpPF, LR, RFD) and 15.4% by kinetic factor (PPF and PaPF) and 12.8% by velocity factor (MV). Furthermore, significant correlations were found between T test with CPD, MV and PPF (0.55, -0.54 and -0.49, respectively), revealing a T test construct related to the ability of generating high level of force in concentric phase, diminishing time of concentric phase, and to reach the change direction point with greatest possible speed.
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Fidan, Hakan. "Verallgemeinertes Testen von unscharf formulierten Hypothesen bei t- und F-Tests /." Aachen : Shaker, 2007. http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&doc_number=017445595&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA.
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Stasiukaitytė, Irma. "Infarkto gydymo įvairiais vaistais statistiniai tyrimo metodai." Master's thesis, Lithuanian Academic Libraries Network (LABT), 2004. http://vddb.library.lt/obj/LT-eLABa-0001:E.02~2004~D_20040610_174400-77084.
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The goal of the present thesis is to ascertain the impact of different drugs, intended for the infarction treatment; investigation of the other factors, which may stipulate bleeding in the course of the operation and within the post-operation period. The investigation was carried out in two stages. During the first stage the data was accumulated for processing (investigation of the sample homogeneity and normality); the second stage implied solution of the statistical tasks (solution of the tasks, which correspond to the goals of the thesis). The methods of data analysis and the models of binary logistic and linear logistic regression were applied. 89 patients, who survived the myocarditis infarction, were investigated and it was ascertained that there is no huge difference in between the tranexamic acid and aprotinin. The bleeding complications may be caused by aspirin, which has been used before the operation. One of the complications, i.e. the drainage, may be predicted, judging from the amount of haemoglobin, haematocrit in the blood as well as creatinin. The model of the binary logistic regression assisted us in drawing the conclusion that smoking, hypothermia, euroscore and other factors produce an impact upon the bleeding complications.
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Charbachi, Peter, and Linus Eklund. "Thesis for the Degree of Bachelor of Science in Computer Science by Peter Charbachi and Linus Eklund : PAIRWISE TESTING FOR PLC EMBEDDED SOFTWARE." Thesis, Mälardalens högskola, Akademin för innovation, design och teknik, 2016. http://urn.kb.se/resolve?urn=urn:nbn:se:mdh:diva-32054.
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In this thesis we investigate the use of pairwise testing for PLC embedded software. We compare these automatically generated tests with tests created manually by industrial engineers. The tests were evaluated in terms of fault detection, code coverage and cost. In addition, we compared pairwise testing with randomly generated tests of the same size as pairwise tests. In order to automatically create test suites for PLC software a previously created tool called Combinatorial Test Tool (CTT) was extended to support pairwise testing using the IPOG algorithm. Once test suites were created using CTT they were executed on real industrial programs. The fault detection was measured using mutation analysis. The results of this thesis showed that manual tests achieved better fault detection (8% better mutation score in average) than tests generated using pairwise testing. Even if pairwise testing performed worse in terms of fault detection than manual testing, it achieved better fault detection in average than random tests of the same size. In addition, manual tests achieved in average 97.29% code coverage compared to 93.95% for pairwise testing, and 84.79% for random testing. By looking closely on all tests, manual testing performed equally good as pairwise in terms of achieved code coverage. Finally, the number of tests for manual testing was lower (12.98 tests in average) compared to pairwise and random testing (21.20 test in average). Interestingly enough, for the majority of the programs pairwise testing resulted in fewer tests than manual testing.
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Widerberg, Carl. "The Two-Sample t-test and the Influence of Outliers : - A simulation study on how the type I error rate is impacted by outliers of different magnitude." Thesis, Uppsala universitet, Statistiska institutionen, 2019. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-375767.
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This study investigates how outliers of different magnitude impact the robustness of the twosample t-test. A simulation study approach is used to analyze the behavior of type I error rates when outliers are added to generated data. Outliers may distort parameter estimates such as the mean and variance and cause misleading test results. Previous research has shown that Welch’s ttest performs better than the traditional Student’s t-test when group variances are unequal. Therefore these two alternative statistics are compared in terms of type I error rates when outliers are added to the samples. The results show that control of type I error rates can be maintained in the presence of a single outlier. Depending on the magnitude of the outlier and the sample size, there are scenarios where the t-test is robust. However, the sensitivity of the t-test is illustrated by deteriorating type I error rates when more than one outlier are included. The comparison between Welch’s t-test and Student’s t-test shows that the former is marginally more robust against outlier influence.
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Marcal, Marcio A. "Evaluation of spinal kinematics using the Fastrak§T§M during the trunk velocity test." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1999. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape9/PQDD_0003/NQ42958.pdf.
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Dodgson, J. H. "The effect of a preliminary test of normality using √b₁ on Student's t Distribution." Thesis, Loughborough University, 1987. https://dspace.lboro.ac.uk/2134/32331.
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Student's t Distribution is introduced with background including comments on its robustness properties. The ad hoc procedure of pretesting data for normality is discussed in the light of current advice, and previous work into its effectiveness reviewed. The approach to the problem is outlined: √b1 for test statistic, the Gram-Charlier distribution for population, approximations using the Johnson system.
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Gaydon, Armelle. "L' enfant sudoué existe-t-il? : le test de Q.I, paradigme de l'évaluation généralisée." Nice, 2011. http://www.theses.fr/2011NICE2001.
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Des biais méthodologiques et idéologiques ont entaché dès l’origine la conception du test de QI (quotient intellectuel) sans jamais entraver sa diffusion massive. A présent les spécialistes de la précocité s’efforcent de faire du surdouement une nouvelle catégorie psychopathologique. Etre intelligent serait-il devenu une maladie? Tel est l’enjeu actuel pour la psychologie et la psychiatrie d’« avant-garde » : constituer une clinique de l’enfant surdoué qui en retour fournirait une légitimité à l’arbitraire taxonomique de départ. Après avoir démantelé la logique à l’œuvre dans l’histoire du test, sa construction et sa diffusion, ce travail se propose d’expliquer pourquoi le public demande toujours plus de mesure et de chiffre, toujours plus de cette « évaluation généralisée » dont le test de QI est le paradigme. Une transformation du Discours du Maître explique le pouvoir de fascination du test. A l’époque de l’inconsistance de l’Autre, alors que les semblants vacillent, que devient l’identification du sujet ? Dans la logique qualifiée par Lacan du nommer-à, les signifiants-maîtres, désormais produits en série, sont installés en place de vérité. Promus ainsi à une puissance quasi divine, ils se présentent comme les « masques de fer » de l’objet plus-de-jouir. Il arrive que le sujet inventif s’en empare pour son compte propre. Souvent il en subit le poids. Donner la parole aux sujets testés surdoués et à leurs familles permet de dégager comment s’organise à grande échelle la ségrégation de ceux que ces signifiants-maîtres épinglent comme différents, mettant au jour certains aspects de la souffrance contemporaine conceptualisée par Freud sous le nom de Malaise dans la culture<br>As soon as it was designed, the IQ test was marred by a methodological and ideological bias. However this did not prevent it being widely spread. Today the tendency is to consider “the exceptionally gifted” as founding a new psychopathological category. Is cleverness a new illness? Such is the question at stake. The new era of psychology and psychiatry has designed a clinical approach of the exceptionally gifted child which comes down to legitimating the arbitrariness of the original taxonomy. After shedding light on the historical and logical foundations of the test, the present study means to explain why the general public crave for more and more measurements and numbers, always more of this “generalized evaluation” of which IQ test is the paradigm. A radical transformation of the Master’s Discourse (Lacan) explains the fascinating power of the test. In the era of the inconsistency of the Other, characterized by the faltering of the semblants, what becomes of the subject’s identification? Following Lacan’s logic of the nominating process, master signifiers - such as “exceptionally gifted” - nowadays mass-produced, are positioned as the truth. Granted some form of divine power they are as the “iron mask” of the plus-de-jouir (Lacan). Sometimes, the inventive subject adopts these signifiers for his own. More often they weigh heavy. Listening to the tested exceptionally gifted allows us to understand how on a large scale their segregation is organized, on the basis of their falling under master signifiers which identify them as different, throwing a new light on some aspects of the contemporary suffering which Freud considered as relevant to the discontents of Civilization
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Dulcini, Enrico. "Spectrum sensing su piattaforma software defined radio: Implementazione e test su stick dvb-t." Bachelor's thesis, Alma Mater Studiorum - Università di Bologna, 2014. http://amslaurea.unibo.it/7094/.
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Uddin, Mohammad Moin. "ROBUST STATISTICAL METHODS FOR NON-NORMAL QUALITY ASSURANCE DATA ANALYSIS IN TRANSPORTATION PROJECTS." UKnowledge, 2011. http://uknowledge.uky.edu/gradschool_diss/153.
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The American Association of Highway and Transportation Officials (AASHTO) and Federal Highway Administration (FHWA) require the use of the statistically based quality assurance (QA) specifications for construction materials. As a result, many of the state highway agencies (SHAs) have implemented the use of a QA specification for highway construction. For these statistically based QA specifications, quality characteristics of most construction materials are assumed normally distributed, however, the normality assumption can be violated in several forms. Distribution of data can be skewed, kurtosis induced, or bimodal. If the process shows evidence of a significant departure from normality, then the quality measures calculated may be erroneous.
In this research study, an extended QA data analysis model is proposed which will significantly improve the Type I error and power of the F-test and t-test, and remove bias estimates of Percent within Limit (PWL) based pay factor calculation. For the F-test, three alternative tests are proposed when sampling distribution is non-normal. These are: 1) Levene’s test; 2) Brown and Forsythe’s test; and 3) O’Brien’s test. One alternative method is proposed for the t-test, which is the non-parametric Wilcoxon - Mann – Whitney Sign Rank test. For PWL based pay factor calculation when lot data suffer non-normality, three schemes were investigated, which are: 1) simple transformation methods, 2) The Clements method, and 3) Modified Box-Cox transformation using “Golden Section Search” method.
The Monte Carlo simulation study revealed that both Levene’s test and Brown and Forsythe’s test are robust alternative tests of variances when underlying sample population distribution is non-normal. Between the t-test and Wilcoxon test, the t-test was found significantly robust even when sample population distribution was severely non-normal. Among the data transformation for PWL based pay factor, the modified Box-Cox transformation using the golden section search method was found to be the most effective in minimizing or removing pay bias. Field QA data was analyzed to validate the model and a Microsoft® Excel macro based software is developed, which can adjust any pay consequences due to non-normality.
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Buch, Thorsten. "A mouse model to test secondary gene rearrangements in the T cell receptor [alpha] locus." [S.l. : s.n.], 2001. http://deposit.ddb.de/cgi-bin/dokserv?idn=961742712.
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Gleichner, Christian [Verfasser], and Heinrich Theodor [Akademischer Betreuer] Vierhaus. "Diagnostischer Test eingebetteter Systeme im Automobil über serielle Standardschnittstellen / Christian Gleichner ; Betreuer: Heinrich T. Vierhaus." Cottbus : BTU Cottbus - Senftenberg, 2015. http://d-nb.info/1114283428/34.
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Mysorekar, Sagar Ravindra. "A GEOSPATIAL FIRE RISK ANALYSIS OF ATHENS, OHIO." Ohio University / OhioLINK, 2006. http://rave.ohiolink.edu/etdc/view?acc_num=ohiou1142460034.
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Tolaszová, Eva. "Analýza EEG signálů při Stroopově testu." Master's thesis, Vysoké učení technické v Brně. Fakulta elektrotechniky a komunikačních technologií, 2009. http://www.nusl.cz/ntk/nusl-218220.
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Master’s thesis deals with the measurement of biological signals for the effect of psychological burden. To monitor this effect was elected Stroop test, which is in the psychology used to detect disorders of attention and concentration. EEG and ECG signals during Stroop test were obtained using the EEG recording systém, in the context of research evoked potentials. As a part of the work it has been designed custom application for analyzing and interpreting data and statistical analysis by t-test.
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Shen, Paul. "Empirical Likelihood Tests For Constant Variance In The Two-Sample Problem." Bowling Green State University / OhioLINK, 2019. http://rave.ohiolink.edu/etdc/view?acc_num=bgsu1544187568883762.
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Göhler, Andreas. "Einheitswurzeltests : (A)DF-versus Cauchyverfahren ; ein Gütevergleich unter Berücksichtigung verschiedener Trendbereinigungsverfahren /." Aachen : Shaker, 2006. http://www.gbv.de/dms/zbw/509082149.pdf.
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Agapay, Alison. "Test of prestressed concrete T-beams retrofitted for shear and flexure using carbon fiber reinforced polymers." Thesis, University of Hawaii at Manoa, 2003. http://hdl.handle.net/10125/6991.
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In 1997, a precast prestressed T-Beam in the Ala Moana Shopping Center Parking Garage was strengthened in flexure using carbon fiber reinforced polymer (CFRP). When the old parking garage was demolished in June 2000 to make way for a new multilevel parking garage, this beam and two control beams were salvaged and transported to the University of Hawaii at Manoa Structural Testing Laboratory for testing. This thesis presents testing of the strengthened beam and a control beam. It also describes the retrofit procedures during field application of the CFRP strips, beam recovery, and preparation for laboratory testing. In addition, a step by step analysis of the predicted strengths is presented. To ensure flexure failure, the beams were retrofitted in shear with CFRP. Two types of wrapping schemes were used and anchorage was provided for the shear retrofit. The left half of each beam was retrofitted with 3" wide double layer CFRP stirrups. The right half of each beam was retrofitted with 12" wide CFRP sheets. After flexural testing, each half of each beam was recovered for shear testing. Flexural test results indicate that the CFRP strengthening provided a 71% increase compared with the control specimen without reducing the beam's ductility. The flexural capacity of the strengthened beam was 21% greater than predicted by ACI 440R-02. The failure shear strength of the beams with CFRP sheets was slightly greater than the ACI 440R-02 prediction. The shear tests indicated delamination of the CFRP stirrups and sheets occurring prior to the maximum shear load. Anchorage at the top and bottom of the beam web helped prevent complete delamination of the CFRP; however further anchorage development is required to maximize the strength of the CFRP shear retrofit.<br>xi, 245 leaves
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Pang, Xiao L. "Assessing the performance of the approximate chi-square and Stout's T statistics with different test structures." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1999. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape8/PQDD_0010/NQ52277.pdf.
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Benelli, Angela. "A test of T and CPT symmetries in the neutral kaon system at the CPLEAR experiment." Thesis, University of Liverpool, 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.243033.
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Howard, James A. E. "Application of the sequential t-test algorithm for analysing regime shifts to the southern Benguela ecosystem." Master's thesis, University of Cape Town, 2007. http://hdl.handle.net/11427/6481.
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Includes bibliographical references (leaves 69-74).<br>Includes abstract.<br>Long-term ecosystem changes, such as regime shifts, have occurred in several marine ecosystems worldwide. Multivariate statistical methods have been used to detect such changes, but they have to date not been applied to the southern Benguela ecosystem. A weakness of many of the methods is that they require long time series data and do not provide robust results at the end of time series. A new method known as the sequential t-test algorithm for analysing regime shifts (STARS) is applied to a set of biological state variables and environmental and anthropogenic forcing variables in the southern Benguela.
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Duffaud, Florence. "Applications "in vitro" et "in vivo", en cancérologie clinique, du test de numération des micronoyaux dans les lymphocytes T binucléés en culture." Aix-Marseille 2, 1997. http://www.theses.fr/1997AIX20651.
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Niklasson, Emma, and Karlsson Tina Sundström. "Analys av försäsongsträningen hos ett svenskt damfotbollslag på elitnivå." Thesis, Högskolan i Halmstad, Biomekanik och biomedicin, 2014. http://urn.kb.se/resolve?urn=urn:nbn:se:hh:diva-25661.
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Syftet med denna studie var att analysera vilken del av försäsongsträningens två cykler som påverkade styrka och explosivitet i nedre extremitet, accelerationsförmåga, agility och anaerob uthållighet genom att sammanställa dessa egenskaper hos kvinnliga elitfotbollsspelare, för att därefter kunna utvärdera om försäsongsträningen förbättrade dessa egenskaper. Tester som kunnat påvisa viktiga och avgörande fysiska kvalitéer hos elitfotbollsspelarevaldes ut och dessa genomfördes vid tre tillfällen; före, under och efter försäsongsträningen. Testerna var; knäböj, vertikalhopp, 15 m sprint, T-test och YO-YO Intermittent Återhämtningstest (YO-YO IÅ).Studien innefattade 24 damfotbollsspelare på elitnivå från alla spelarpositioner. Till den andra testomgången observerades en signifikant förbättring av styrka, agility och anaerob uthållighet. Vid de andra testerna observerades ingen skillnad. Första delen av försäsongsträningen utvecklade till viss del spelarna åt rätt håll genom en förbättring av styrkan i nedre extremiteten. Den signifikanta förbättringen i agility och anaerob uthållighet kom lite för tidigt, det vill säga under den första cykeln avförsäsongsträningen, vilket hade varit mer önskvärt efter den andra cykeln. Detta innebär attandra viktiga egenskaper kan ha försummats.<br>The purpose of this study was to analyze which part of the pre-season trainings two cycles that affected strength and power in lower extremities, acceleration, agility and anaerobic endurance by compiling these abilities of a female elite soccer player team, and then evaluate whether the pre-season training improved these abilities. Tests that could prove important and crucial physical qualities in elite soccer players were selected and then performed on three occasions; before, during and after the pre-seasontraining. The selected tests were; squat, vertical jump, 15 m sprint, T-test and YO-YO Intermittent Recovery Test (YO-YO IR). The study included 24 female elite soccer playersfrom all playing positions. A significant improvement in strength, agility and anaerobic endurance were measured in the second test round. In the other tests there were no difference observed. The first cycle of the pre-season training partly developed the players in the right direction, which the significant improvement in strength revealed. The significant improvement in the agility and anaerobic endurance occurred a little too early, it would have been more beneficial after the second cycle. This means that other important qualities might have been neglected.
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McIntee, Erin. "FORENSIC ANALYSIS OF AUTOMOBILE PAINTS BY ATOMIC AND MOLECULAR SPECTROSCOPIC METHODS AND STATISTICAL DATA ANALYSES." Master's thesis, University of Central Florida, 2008. http://digital.library.ucf.edu/cdm/ref/collection/ETD/id/3131.
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The analysis of 110 automotive paint samples was conducted for the research presented here. Laser-induced breakdown spectroscopy (LIBS) was the central instrument utilized for analysis although scanning electron microscopy / energy dispersive x-ray spectroscopy (SEM/EDS) and Fourier transform infrared spectroscopy – attenuated total reflection (FTIR-ATR) analyses were also performed. Two separate methods of LIBS analysis of samples were used: a cross sectional analysis and a drill down analysis. SEM/EDS analysis focused on the cross section while FTIR-ATR analysis concentrated on the clearcoat layer. Several different data/statistical analyses were evaluated including principal components analysis (PCA), two tailed t-tests based on several different metrics (Hit Quality Index (HQI), Pearson's correlation and Sorenson index), multivariate analysis of variance and receiver operating characteristic (ROC) curves. Full spectrum data analysis from LIBS spectra resulted in 99.7% discrimination between different sample comparisons and 12% between same sample comparisons based on HQI and t-tests. Peak analysis of LIBS spectra resulted in 87.5% discrimination between different sample comparisons and 5% between same sample comparisons based on MANOVA. When combining the results of the FTIR-ATR and SEM/EDS analyses, 88% of the samples could be discriminated.<br>M.S.<br>Department of Chemistry<br>Sciences<br>Forensic Science MS
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Reed, John Richard. "The Mantoux Test : a model for tracking T cell differentiation in the skin during secondary immune challenge." Thesis, University College London (University of London), 2005. http://discovery.ucl.ac.uk/1446273/.
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In this study, we hypothesized that T cells differentiate in the skin as a consequence of localised proliferation at the site of secondary immune challenge in humans. One consequence of cellular proliferation is telomere shortening, which can be counteracted by telomerase. It is recognised that telomerase is up-regulated in activated T cells that are resident in lymphoid tissues or the blood. We have used the Mantoux Test (MT), a secondary immune response, to determine the degree of cellular differentiation in the skin and its consequences during an episode of cutaneous inflammation. We have established a skin suction blister technique to isolate lymphocytes from MTs up to 19 days after induction for flow cytometric analysis, heteroduplex analysis, cell culture and measurement of telomerase activity (TRAP assay). Skin biopsies were also collected for immunohistochemical staining. Marked antigen-specific CD4+ T cell expansion with preserved clonality was observed in the skin during the MT. In contrast to recent murine studies, we found that this expansion was mediated in part by the extensive proliferation of CD4+ T cells in the skin. This was associated with substantial telomeric shortening in the antigen-specific CD4+ T cells in the skin, indicating accelerated cellular differentiation. Despite the development of a highly differentiated population of CD4+ T cells during the MT, there appeared to be no increase in the proportion of anergic/suppressive CD4+CD25+ T cells, which might mediate the down-regulation of inflammation during resolution. The erosion of telomeres appeared to be mediated by the reversible inhibition of telomerase by type 1 interferons in vivo. This reversible inhibition was distinct from the irreversible down-regulation of telomerase that was observed when MT skin T cells were repeatedly activated in vitro culminating in cell senescence. The inhibition of telomerase activity in T cells during secondary immune responses in the skin represents a possible control checkpoint that may limit uncontrolled T cell expansion in non-lymphoid tissues in vivo.
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Rupasinghe, Arachchige Don Hasthika Sriyantha. "BOOTSTRAPPING ANALOGS OF THE ONE WAY MANOVA TEST." OpenSIUC, 2017. https://opensiuc.lib.siu.edu/dissertations/1425.
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The classical one way MANOVA model is used to test whether the mean measurements are the same or differ across p groups, and assumes that the covariance matrix of each group is the same. This work suggests using the Olive (2017abc) bootstrap technique to develop analogs of one way MANOVA test. A large sample theory test has also been developed. The bootstrap tests can have considerable outlier resistance, and the tests do not need the population covariance matrices to be equal. The two sample Hotelling's T^2 test is the special case of the one way MANOVA model when p =2.
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Gomes, Priscila da Silva. "Distribuição normal assimétrica para dados de expressão gênica." Universidade Federal de São Carlos, 2009. https://repositorio.ufscar.br/handle/ufscar/4530.
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Previous issue date: 2009-04-17<br>Financiadora de Estudos e Projetos<br>Microarrays technologies are used to measure the expression levels of a large amount of genes or fragments of genes simultaneously in diferent situations. This technology is useful to determine genes that are responsible for genetic diseases. A common statistical methodology used to determine whether a gene g has evidences to diferent expression levels is the t-test which requires the assumption of normality for the data
(Saraiva, 2006; Baldi & Long, 2001). However this assumption sometimes does not agree with the nature of the analyzed data. In this work we use the skew-normal distribution
described formally by Azzalini (1985), which has the normal distribution as a particular case, in order to relax the assumption of normality. Considering a frequentist approach
we made a simulation study to detect diferences between the gene expression levels in situations of control and treatment through the t-test. Another simulation was made to
examine the power of the t-test when we assume an asymmetrical model for the data. Also we used the likelihood ratio test to verify the adequability of an asymmetrical model
for the data.<br>Os microarrays são ferramentas utilizadas para medir os níveis de expressão de uma grande quantidade de genes ou fragmentos de genes simultaneamente em situações variadas. Com esta ferramenta é possível determinar possíveis genes causadores de doenças de origem genética. Uma abordagem estatística comumente utilizada para determinar se um gene g apresenta evidências para níveis de expressão diferentes consiste no teste t, que exige a suposição de normalidade aos dados (Saraiva, 2006; Baldi & Long, 2001). No entanto, esta suposição pode não condizer com a natureza dos dados analisados. Neste trabalho, será utilizada a distribuição normal assimétrica descrita formalmente por Azzalini (1985), que tem a distribuição normal como caso particular, com o intuito de
flexibilizar a suposição de normalidade. Considerando a abordagem clássica, é realizado um estudo de simulação para detectar diferenças entre os níveis de expressão gênica em
situações de controle e tratamento através do teste t, também é considerado um estudo de simulação para analisar o poder do teste t quando é assumido um modelo assimétrico
para o conjunto de dados. Também é realizado o teste da razão de verossimilhança, para verificar se o ajuste de um modelo assimétrico aos dados é adequado.
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Janstad, Tobias. "Case study of a contract system : considering pulp prices from 1996-2006." Thesis, Växjö University, School of Mathematics and Systems Engineering, 2007. http://urn.kb.se/resolve?urn=urn:nbn:se:vxu:diva-1684.
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<p>Södra Cell sells 1 900 000 ton pulp every year. Of this 490 000 tonne is sold with a contract system based on a pricing index called PIX NBSK. This index was started in 1996 and reflects the price of pulp from conferious forest. We study the NBSK PIX value of softwood from October 1996 to December 2006.</p><p>People working in this branch known that there is strong periodicity in the prices. We use predictive analysis to see if clients can benefit from the periodicity and use the options in the contract system Södra offers today. We conclude that a drawback for the current contract system is that there are too many contracts in proportion to the duration time that is one year for all contracts. Using a time series model called ARMA we make successfull predictions the price difference between two contracts. Based on this prediction we change between these contracts, reducing the price with 0.81% in mean during 1997-2006. Due to the total turnover, if all clients would used such predictions during 1997-2006 Södra's income would have been reduced with 2.77 million USD a year in mean.</p><p>The prices used before PIX are called list prices. The list prices seem to behave like the PIX index. Supposing that the same contract system we see in PIX today was used 1975-2006 with the list price as the base index I made a prediction of the list prices from 1986-2006. Thanks to my predictions, if I had been a client during this period and under mentioned considerations I would have been buying pulp to a price reduced with 0.57%.</p><p>If clients had known the PIX between 1996-2006 in say 1995 Södra's contract system based on PIX would give them a price reduction that were 1.5% in mean during 1996-2006. Price reduction is not possible all years, but when it occurs it can be as big as 3% of the price. Suppose the clients always choose the contract with the lowest price and thereby get a reduced price over time. Then with 95% probability over a long period the price reduction is somewhere in between 0.4-2.7%.</p><p>To strangle this price reduction possibility for the clients there are two ways to go: either reduce the number of contracts or extend the duration time of the contracts.</p><p>To find a suitable duration time, we do spectral density estimation to get indications of which periods that are most important. From this we see that PIX index has a period of five years, wavelet approximated PIX index has 3.4 years and the list prices has a period of 5.6 years. This indicates that current duration time one year is too short. Therefore if it wouldn't effect Södra's clients, an extension of the duration time from one to five years would be good.</p><p>If Södra don't extend the duration time of the contracts my recommendation is to have fewer contracts. The possibility to change between the contracts ''average last three months'' and ''average current month'' every other year is the weakest point of today's system. Therefore I recommend stop selling pulp to the contract ''average PIX last three months''.</p><p>We can't prove any longterm difference between the contracts. If Södra chooses to have just one contract from this point of view it does not matter which one they choose. However, it seems like a good idea to follow the global market and therefore I recommend to choose ''average PIX current month'' rather than ''average PIX last three months'' which lags behind the market front. Since the price ''average current month'' is available at FOEX web page I think Södra should choose this contract if they decide to have only one contract.</p><br><p>Södra Cell säljer årligen 1 900 000 ton pappersmassa. Av denna mängd säljs 490 000 ton enligt ett kontraktsystem baserat på ett prisindex som heter PIX NBSK. Detta index introducerades 1996 och reflekterar priset på pappersmassa gjord av barrträd. Jag studerar priset på indexet från Oktober 1996 till December 2006.</p><p>Dagens kontraktsystem är baserat på kontrakt med löptiden ett år. Jag undersöker om man kan prediktera prisskilllnaden mellan kontrakten, dra nytta att dagens löptid som bara är ett år och välja det kontrakt som ger det billigaste priset så ofta att priset över lång tid reduceras. När man predikterar gör man en uppskattningen av framtiden utifrån en modell av hur framtid beror på dåtid och nutid. Den modell jag har använt kallas ARMA. Denna tillsammans med priserna på pappersmassa från 1975 och framåt gav mig ett fruktbart sätt att förutsäga priserna. Resultatet blev ett pris reducerat med 0.81% i medel under perioden 1996-2006. Eftersom Södra ha så stor försäljningsvolym skulle de ha förlorat 2.27 miljoner dollar per ton i medel om alla kunder ha spekulerat utifrån den modellen jag använde.</p><p>Om dagens kontraktsystem hade börjat användas 1975 med listpriserna som bas hade en kund som använt min prediktionsmetod fått ett pris reducerat med 0.57% under perioden 1986-2006.</p><p>Om kunderna i förväg hade vetat priset under 1996-2001 gav det nuvarande systemet en reducerad medelintäkt med 1.5% av priset. Enskilda år reducerades intäkten med så mycket som 3%. Beräknar man konfidensintervall för prisreduktionerna så inser man att på lång sikt kommer dessa vara av storleksordningen 0.4-2.7% med sannolikheten 95%. Detta förutsatt att klienterna kan se in i framtiden. Siffran 2.7% alltså ett mått på hur stor risk man tar med dagens system. Jag tror inte att klienterna kommer reducera priset med 2.7% med nuvarande system, men det är en övre gräns.</p><p>De gynsamma prediktionerna har sitt ursprung i att det finns periodicitet i priserna. Jag undersöker denna periodicitet med spektralanalys. Periodiciteten för PIX indexet är starkast kring 5 år. En wavelet-approximation av PIX-indexet hade störst periodicitet kring 3.4 år. Listpriserna hade starkast periodicitet kring 5.6 år. Detta indikerar att den nuvarande löptiden, ett år, är för kort. En lämpligare löptid för kontrakten är 5 år.</p><p>Förmodligen är fem års löptid alltför lång tid att binda sig för många kunder. Därför föreslår jag att man reducerar antalet kontrakt istället. Den största svagheten i dagens system är den korta löptiden tillsammans med kontrakten ''average current month'' och ''average last three months''. Jag rekommenderar att man slutar erbjuda kontraktet ''average last three months''. Det allra säkraste är att endast erbjuda ett kontrakt. Vi har inte kunnat påvisa några skillnader över lång sikt mellan kontrakten såtillvida att något kontrakt skulle ge ett lägre medelpris än ett annat. Ur den aspekten är det godtyckligt vilket kontrakt man väljer, men det verkar vettigt att följa den globala marknaden. Därför är det eftersläpande kontraktet ''average PIX last three months'' inte att rekommendera, välj heller ''average PIX current month''. Ett annat argument för att välja ''average PIX current month'' är att dessa priser finns på FOEX hemsida och inga extra beräkningar behöver göras.</p>
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Jennings, Martha. "The robustness of validity and efficiency of the one-sample t test in the presence of normal contamination." Thesis, University of Ottawa (Canada), 1994. http://hdl.handle.net/10393/6629.
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The performance of parametric tests given data which are essentially normal but contain outliers is largely unknown. In this Monte Carlo study the robustness of validity and efficiency for the one-sample location problem are investigated. The Type I error rate and power of the one-sample t test given a normal underlying population are compared with the performance of this test given a systematic range of outlier contamination in the underlying population. Sample sizes of 8, 16, 32, 64, and 128 are included in the design. The robustness of validity results are explored using three sets of regression models. The first set of models is constructed using the parameters of the contamination model and is intended to inform the social science methodologist. The second set of models is constructed using skewness and kurtosis values. A third set of models is developed using an index of contamination proposed by Zumbo (1993). This set of models has practical relevance to the data analyst confronted with outlier contaminated data. Robustness of efficiency results are expressed using both power curves and a proposed fairly stringent criterion for power. In general, the results indicate that the one-sample t test demonstrates fairly stringent robustness of validity for all the symmetric contamination explored. When contamination is asymmetric the Type I error rate becomes inflated as the proportion of contamination increases. If robustness of validity is intact, power is not greatly affected when medium or large effect sizes are examined. This is not necessarily true for small effect sizes and the problems are further exacerbated when sample sizes are also small.
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Palmlöf, Anders. "Studierelaterad stress : En kvantitativ studie som undersöker kön, ålder- och utbildningsskillnader bland studenter på Mälardalens högskola." Thesis, Mälardalens högskola, Akademin för hälsa, vård och välfärd, 2017. http://urn.kb.se/resolve?urn=urn:nbn:se:mdh:diva-36760.
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Stress and psychosomatic symptoms are an increasing problem in todays society, where adolescents are a group more exposed than others. Over the years, stress as a concept has been developed and is today linked to chronic diseases, depression and cardiovascular diseases. Many people experience long lasting, chronic stress which the body is no good at handling. Women seem to generally experience more stress than men, which can be related to the society’s view of gender. This can also be linked to how men and women handle stress, which seem to be in different ways. Sense of coherence can also be linked to stress, where higher sense of coherence correlates with lower experienced stress and lower sense of coherence with higher stress, which also can be linked with age, though there is a need for more studies on the subject to show this. The aim of this study is to investigate a possible connection between age, gender, type of education and stress. The study has a comfort selection with a total of 79 respondents, of which are 56 women and 23 men. The result of this study shows no significant difference between gender, age, type of education and stress, though there is a slight difference in the descriptive analysis. To obtain a significant result, the study selection would’ve had to be representable and a higher number of respondents would have had to be included.<br>Stress och psykosomatiska symtom är ett ökande problem i dagens samhälle där ungdomar är speciellt utsatta. Stress har som begrepp utvecklats under årens gång, men kopplas idag ihop till flera kroniska sjukdomar, nedstämdhet och hjärt- och kärlsjukdomar. Människor utsätts idag för långvarig, kronisk stress, vilket kroppen inte är konstruerad för. Kvinnor verkar generellt sett uppleva mer stress i vardagen än män, vilket kan kopplas till samhällets syn på kön och genus. Detta kan även kopplas till hur män och kvinnor hanterar stress, vilket verkar vara annorlunda. Ytterligare så kan känsla av sammanhang kopplas till stress, där en högre känsla av sammanhang har en samband med lägre stress och tvärt om. Forskare menar att graden av känsla av sammanhang ökar med åldern, vilket då även kan kopplas till en lägre stressnivå vid högre ålder. Dock behövs mer forskning för att fastställa detta. Syftet med studien är att undersöka om det finns ett samband mellan ålder, kön, typ av utbildning och stress. Studien har ett bekvämlighetsurval med totalt 79 respondenter, varav 56 kvinnor och 23 män. Resultatet i denna studie visar inte på någon signifikant skillnad mellan kön, ålder och utbildning i relation till stress, då endast vissa små skillnader identifieras i den deskriptiva analysen. För att kunnat få ett signifikant resultat hade studien behövt ha en annan typ av urval och ett större antal respondenter.
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Chen, Cong. "Side Channel Leakage Exploitation, Mitigation and Detection of Emerging Cryptosystems." Digital WPI, 2018. https://digitalcommons.wpi.edu/etd-dissertations/472.
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With the emerging computing technologies and applications in the past decades, cryptography is facing tremendous challenges in its position of guarding our digital world.
The advent of quantum computers is potentially going to cease the dominance of RSA and other public key algorithms based on hard problems of factorization and discrete logarithm. In order to protect the Internet at post-quantum era, great efforts have been dedicated to the design of RSA substitutions. One of them is code- based McEliece public key schemes which are immune to quantum attacks.
Meanwhile, new infrastructures like Internet of Things are bringing the world enormous benefits but, due to the resource-constrained nature, require compact and still reliable cryptographic solutions. Motivated by this, many lightweight cryptographic algorithms are introduced.
Nevertheless, side channel attack is still a practical threat for implementations of these new algorithms if no countermeasures are employed. In the past decades two major categories of side channel countermeasures, namely masking and hiding, have been studied to mitigate the threat of such attacks. As a masking countermeasure, Threshold Implementation becomes popular in recent years. It is sound in providing provable side channel resistance for hardware-based cryptosystems but meanwhile it also incurs significant overheads which need further optimization for constrained applications. Masking, especially for higher order masking schemes, requires low signal-to-noise ratio to be effective which can be achieved by applying hiding countermeasures.
In order to evaluate side channel resistance of countermeasures, several tools have been introduced. Due to its simplicity, TVLA is being accepted by academy and industry as a one-size-fit-all leakage detection methodolgy that can be used by non-experts. However, its effectiveness can be negatively impacted by environmental factors such as temperature variations. Thus, a robust and simple evaluation method is desired.
In this dissertation, we first show how differential power analysis can efficiently exploit the power consumption of a McEliece implementation to recover the private key.
Then, we apply Threshold Implementation scheme in order to protect from the proposed attack. This is, to the best of our knowledge, the first time of applying Threshold Implementation in a public key cryptosystem.
Next, we investigate the reduction of shares in Threshold Implementation so as to bring down its overhead for constrained applications. Our study shows that Threshold Implementation using only two shares reduces the overheads while still provides reliable first-order resistance but in the meantime it also leaks a strong second-order leakage.
We also propose a hiding countermeasure, namely balanced encoding scheme based on the idea of Dual- Rail Pre-charge logic style in hardwares. We show that it is effective to mitigate the leakage and can be combined with masking schemes to achieve better resistance.
Finally, we study paired t-test versus Welch's t-test in the original TVLA and show its robustness against environmental noises. We also found that using moving average in computing t statistics can detect higher-order leakage faster.
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West, Natalie J. "Using Professional Development to Build Pre-Service Teachers' Self-Efficacy for Helping Students with Posttraumatic Stress Disorder to Learn." TopSCHOLAR®, 2017. http://digitalcommons.wku.edu/theses/1933.
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The current study determined if a professional development on PTSD would improve pre-service teachers’ self-efficacy for helping students with posttraumatic stress disorder (PTSD) to learn. Participants consisted of 59 college students from one large, comprehensive, Mid-Southern university who were enrolled in an education program and an educational psychology course. Using a quasi-experimental method, participants either received the PTSD professional development (treatment) or regular instruction (control group). All participants completed a measure of demographics, a pre-test measure of selfefficacy for helping students with PTSD to learn, which was further dissected into four constructs (i.e., self-efficacy for identifying students with PTSD, adapting instruction to maximize learning, creating a safe and secure environment, and finding help), and a posttest measure of the same self-efficacy items. A one-way MANOVA indicated statistically significant differences between the two groups in self-efficacy for identifying students with PTSD. Furthermore, a paired-samples t-test revealed that the treatment groups’ selfefficacy scores on all four constructs significantly improved from pre- to post-test. Information is offered to support this finding; additionally, possible reasons for nonsignificant findings are discussed.
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Nováková, Aneta. "Změny daňových mixů zemí EU v důsledku krize." Master's thesis, Vysoká škola ekonomická v Praze, 2012. http://www.nusl.cz/ntk/nusl-150303.
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The thesis deals with the question whether the financial crisis caused changes in the structure of tax revenues in the EU Member States. It's necessary to specify trends in the tax mixes that helps us to determine whether the changes in the structure can be really caused by the crisis or it is EU long-term trend. The analysis focuses on indirect taxes, social contributions and direct taxes that are analyzed separately as personal income taxes and corporate income taxes. The analyzed period is the beginning of the crisis. These are mostly the changes in the turning period pre-crisis and crisis (2006 and 2007 are compared with 2008 and 2009). The analysis is performed by t-tests.
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Kučírková, Dagmar. "Sbližování daňových systémů v EU." Master's thesis, Vysoká škola ekonomická v Praze, 2014. http://www.nusl.cz/ntk/nusl-192658.
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The aim of the thesis is to evaluate whether is there a convergence in the tax systems of the EU Member States or not. The first chapter describes a development in a process of tax coordination and harmonization of the EU Member States. The next chapter focuses on a description and comparison of the current state of the tax systems in the European Union. The third chapter deals with the statistical evaluation of the development of individual variables - overall tax quota, tax quota of individual taxes, implicit tax rates, statutory tax rates, for individual taxes and a group of taxes between 1995 and 2011 period. The fourth chapter summarizes the results of the analysis.
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Milhem, Clara. "Caractérisation et validation d'une signature moléculaire des lymphocytes T régulateurs humains et de leur microenvironnement : mise en place d'un test compagnon." Thesis, Université de Lille (2022-....), 2022. http://www.theses.fr/2022ULILS008.
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Les lymphocytes T régulateurs (Treg) sont une sous-population de cellules immunitaires connues pour leur rôle prépondérant dans la modulation de la réponse immunitaire innée et adaptative. Ils ont un rôle majeur dans la physiologie de l’organisme, mais également dans la mise en place des pathologies comme les inflammations chroniques, les maladies auto-immunes et les cancers. L’intérêt de mieux caractériser et suivre l’évolution des Tregs n’est plus à démontrer, qui plus est à l’ère des immunothérapies. En ce sens, notre équipe a établi une signature moléculaire unique des Tregs, basée sur l’expression de 81 gènes permettant de les caractériser et d’évaluer leur modulation. Ainsi, la validation de la signature moléculaire aboutira à l’établissement d’un kit compagnon couplé à un algorithme de lecture. Cela permettra de prévenir de façon fiable et rapide les effets indésirables de nouvelles molécules, de la recherche jusqu'à la clinique, vis-à-vis du système immunitaire.La première partie des résultats de qPCR sur les Tregs isolés d’individus sains a permis de conclure à la stabilité d’expression pour 84% des gènes de la signature. Ce ratio monte jusqu’à 92% pour l’évaluation de la stabilité d’expression des gènes dans les PBMC des mêmes donneurs. Ces résultats, très prometteurs, nécessitent d’être confirmés sur une plus grande population. Ainsi, l’étude d’une corrélation mathématique entre les niveaux d’expressions géniques des Tregs isolés et des PBMC autologues a été entrepris. Cette étude a permis de montrer que l’expression de 11 gènes est corrélée de manière linéaire à plus de 70% entre Tregs isolés et PBMC autologues.Dans un second temps, ce travail a permis d’évaluer la réponse de la signature face à des agents modulateurs décrits pour activer ou inhiber les Tregs. Cette étape a validé la bonne réactivité de certains gènes face aux agents modulateurs. C’est le cas de 4 gènes, qui diminuent significativement quand l’activité suppressive des Tregs est inhibée par un anticorps monoclonal anti-galectine-9. Néanmoins, l’analyse de variance multivariée n’a pas permis de montrer que les variations d’expression observées sont exclusivement dues au traitement sur la base des 10 donneurs, il semble que la variabilité interindividuelle entre en jeu dans l’analyse de certains groupes de gènes.Enfin, le comportement de la signature a été évalué chez 4 patients, inclus dans un essai clinique pour le traitement de différents types de cancer par radiothérapie stéréotaxique hypo fractionnée à haute dose. Encore une fois, les résultats obtenus sont très prometteurs puisque l’évolution biologique et clinique des patients est corrélée avec l’évolution d’expression des gènes de la signature. Ces données constituent une première confirmation de l’utilité d’une telle signature dans l’immuno-monitoring des patients.Ces études sont très encourageantes pour le développement d’un algorithme de lecture automatisé des résultats. Ainsi, le kit pourra être positionnable sur le marché de la recherche fondamentale jusqu’en clinique, pour l’évaluation des Tregs et leurs microenvironnements dans tous types d’études<br>Regulatory T cells (Treg) are an immune cell subpopulation known for their important role in innate and adaptive immune response contraction. They have a major role in physiology, but also in pathologies outcome such as chronic inflammations, autoimmune diseases and cancers. A better characterization and follow of Treg evolution are clearly needed, especially in the era of immunotherapies. Our team has established a unique Treg molecular signature based on the expression of 81 genes, allowing to characterize and to evaluate Treg modulation. Thus, the molecular signature validation will lead to the establishment of a companion kit coupled with a reading algorithm. This will allow to reliably and rapidly prevent the adverse effects of new molecules, from research to the clinic, regarding the immune system.The first part of the RT-PCR results on healthy donors isolated Tregs allowed to conclude that 84% of the genes have stable expression. This ratio rises to 92% for the stability evaluation of gene expression in PBMC from the same donors. These results are very promising, but need to be confirmed on a larger population. To go further the presence of a mathematical correlation between isolated Tregs and autologous PBMC gene expression levels, have been researched. This study showed that the expression of 11 gene are linearly correlated beyond 70%. Afterward, the signature response to modulating agents described to activate or inhibit Tregs have been asses. Here, the genes good response to modulating agents is proved: 4 gene expression decrease significantly when Tregs suppressive activity is inhibited by an anti-galectin-9 monoclonal antibody. Nevertheless, multivariate analysis of variance failed to show that the expression variations are exclusively due to treatment with 10 donors, it seems that interindividual variability has a role in some gene response to modulator. Finally, the signature behavior was evaluated in 4 patients, included in a clinical trial for cancer treatment by high dose hypo fractionated stereotactic radiotherapy. Once again, the results obtained are very promising since the biological and clinical patients’ evolution is correlated with the gene expression modulation. These data constitute a first confirmation of the usefulness of such a signature in the immuno-monitoring of patients.These outcomes are very encouraging for the development of an automated reading algorithm. Thus, the kit could be positioned on the market from basic research to the clinic, for the evaluation of Tregs and their micro environments in all types of studies
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Jahangir, Muhammad Nasir, and Muhammad Fahadullah. "Statistical Analysis of Team Training in Emergency Management Simulator System." Thesis, Linköping University, Department of Computer and Information Science, 2009. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-51990.
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<p>In this thesis work, we compare the results obtained from two kinds of teams forming a hierarchical organization participating in a fire fighting simulation environment called as C3Fire. First kind of teams used paper-based maps for spatial reasoning of the command tool while the other kind of teams has GIS based maps with full access to positioning data of the fire fighting units as well as sensor information about fire break.</p><p>The collected data was from 11 teams of each kind having 6 members in each team making a total of 132 participants belonging to different parts of the world.</p><p>We made a statistical analysis on the data with help of T-Test statistical medhod and a tool is designed by using Java as programming language and PostgreSQL database for importing data from log files and then applying statistical T-Test method on the fetching data from log files.The results are stored in database as well as excel files. Then a comparison is done to analyze the unit performance, communication and efficiency of both kinds of teams.</p>
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Albersmann, Benjamin T. [Verfasser], Reiner [Akademischer Betreuer] Quick, and Dirk [Akademischer Betreuer] Schiereck. "IFRS Goodwill Impairment Test - Audit Approach, Earnings Management, and Capital Market Perception / Benjamin T. Albersmann ; Reiner Quick, Dirk Schiereck." Darmstadt : Universitäts- und Landesbibliothek Darmstadt, 2017. http://d-nb.info/1133262023/34.
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Girma, Mekdes [Verfasser], and T. [Akademischer Betreuer] Zwick. "Concepts for Short Range Millimeter-wave Miniaturized Radar Systems with Built-in Self-Test / Mekdes Girma ; Betreuer: T. Zwick." Karlsruhe : KIT Scientific Publishing, 2019. http://d-nb.info/1199538124/34.
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Tarikci, Abdurrahman. "Analysis Of Turkish Art Music Songs Via Fractal Dimension." Phd thesis, METU, 2010. http://etd.lib.metu.edu.tr/upload/12611567/index.pdf.
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Forty songs are randomly selected from four randomly selected maqams. Songs are restricted to be in sofyan usü<br>l (sofyan rhythmic form) to check the statistical significance. Next, fractal dimensions of the these songs are calculated by using two different method and two different scattering diagrams. In the first method, fractal dimensions are calculated via two different box sizes. As for second method, successively decreased box sizes are used. In addition, standard deviation and mean values of the fractal dimensions are calculated to check the relation between fractal dimension and maqam. T test and F test are applied to check the statistical significance. After these calculations, it is verified that fractal dimension can be used as an information source concerning the Turkish art music songs which are nonlinear dynamical systems. Moreover, it is showed that maqams can have their own fractal dimension for low resolutions. On the other hand, it is seen that for high resolutions all songs have almost same fractal dimension.
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Camps, François-David. "Le traitement psychique de la perte dans les schizophrénies : approche psychanalytique et projective." Thesis, Paris 5, 2013. http://www.theses.fr/2013PA05H117.
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L’ensemble des travaux psychiatriques actuels se concentre essentiellement sur l’aspect symptomatiquement de la dépression chez les sujets schizophrènes. A l’inverse, nous avons tenté d’étudier non pas la dépression clinique, mais les problématiques de perte dans les fonctionnements psychiques des sujets marqués par le processus schizophrénique. Autrement-dit, nous avons interrogé le rôle et les fonctions de la perte au sein d’un moi ayant perdu ses frontières et le sentiment de son existence, dans un fonctionnement psychique où les limites soi/non-soi sont aléatoires, les défenses narcissiques précaires ou inefficaces. A travers l’examen de la perte chez le schizophrène, c’est donc l’étude des diverses modalités de la relation d’objet et des affects associés dans cette pathologie que nous avons étudié. Il s’agissait donc de passer au-delà de l’aspect purement symptomatologique et phénoménologique de la dépression chez le sujet schizophrène pour interroger sa fonction au niveau métapsychologique. Nous nous sommes intéressés aux diverses opérations psychiques mises en œuvre par les sujets atteint de schizophrénie pour faire face aux divers problématiques de perte. Par problématiques de perte, nous entendons toutes les situations où le sujet a perdu un objet, ou doit y renoncer, que ce soit dans les problématiques de séparation d'avec l'objet primaire, l’abord de la position dépressive, de mélancolie, de deuil. Nous avons donc interrogé les articulations et intrications entre problématiques de perte et problématiques dissociatives.Notre recherche est animée par l’idée que la schizophrénie est un processus qui détruit les liens objectaux et les représentations d’objet mais surtout qui empêche d’en reconstruire de nouveaux, en cela il s’attaque à l’objectalité même. Persuadé que les schizophrénies procèdent d’une incapacité à utiliser le dipôle narcissisme-objet, nous souhaitions observer les diverses « constellations relationnelles » au sein des fonctionnements psychiques marqués par la schizophrénie, à travers leur représentations. Notre idée était que les différentes formes de schizophrénies témoignaient des différentes modalités d’approche de l’objet ou de la relation à l’objet.Notre première hypothèse postule que, plus les fonctionnements psychiques marqués par le processus schizophrénique sont habités par des représentations d'objet, même si ces objets sont partiels, persécuteurs, mal différenciés ou incestueux, plus la pensée reste « vivante » même si elle est désorganisée. Une seconde hypothèse postule que chez les sujets atteints par un processus schizophrénique il n'y a pas de possibilité d'élaborer les problématiques de perte, même si on observe de grandes différences individuelles. Cependant la présence d’éléments témoignant de problématiques de perte peut venir signer un assouplissement partiel des défenses psychotiques et révéler un fonctionnement de l’appareil psychique moins abrasé. Une sous-hypothèse propose l’idée que la reconnaissance de problématiques de perte est possible, chez certains sujets atteints de schizophrénie, le traitement de la perte diffère alors de celui du deuil ou de la mélancolie. Enfin une troisième hypothèse porte sur l’existence d’un processus mélancolique que nous pourrions repérer dans certaines formes de schizophrénies (les formes dysthymiques) qui ne peut pas se constituer véritablement pour autant<br>Our thesis does not deal with clinical depression but with the issue of loss within the psychic functioning of patients marked by a schizophrenic process. By issues of loss we mean all situations in which the patient has lost something, but also separation, depression, melancholy and grief. In order to examine the standard metapsychological function and to observe the articulations and entanglements existing between issues of loss and dissociative problems we surveyed the functions of loss associated with a personality that had lost its sense of confines and existence beyond the purely symptomatic aspect of depression. Our first hypothesis is that the more psychic functions are marked by a schizophrenic process inhabited by object representations, even if these representations are partial, persecuting, poorly differentiated or incestuous, the more the thought remains " alive " even if it is disorganised. A second hypothesis is that in schizophrenic patients there is no possibility of developing issues of loss. The presence of depressive elements can however signal a partial easing of psychotic defenses. A sub-hypothesis is that the recognition of the problem of loss is possible in dysthymic patients but that the treatment differs from that aimed at grief and melancholy. A third hypothesis centres around the existence of a melancholic process in some schizophrenics (dysthymia). To test these hypotheses we studied the psychic functioning of twenty patients diagnosed as " schizophrenic "according to CIM 10. This was based on projective mediation tests (Rorschach and TAT) looking at differences and invariables associated with the treatment of loss and depression. We demonstrated the specificity of psychic functioning for each schizophrenic in terms of relationships, emotions and sensations relating to the issue of loss. Our results demonstrate that the functioning of patients affected by schizophrenia, far from remaining focused on one object tends instead to defend itself from the influence of the object upon the ego. Behind a more delusional and hallucinatory appearance the mental functioning of patients with paranoid schizophrenia and dysthymia is more disorganised, but paradoxically " more alive ", more driven by representations of objects that appear as an outward expression of less deadly psychic functioning, this despite the noisier symptoms in the form of simple undifferentiated or hebephrenic schizophrenia. Our work shows that if problems and depressive effects can be seen they lead to different defensive treatments which are invariably underpinned by denials. The presence of isolated depressive effects does not lead to recognisable problems associated with loss for the patient. We therefore conclude that if schizophrenics recognise situations of loss then that cannot be the work of psychic integration. This impossibility depends on the intensity of the destructive schizophrenic process and the capacity to implement a narcissistic reinvestment in itself, even if only transitory, albeit with significant individual differences. Finally, if we examine the outlines of the melancholy movements within our participants, they cannot be carried through to the end because of the inconsistency of the object lost, its potentially persecuting character and the absence of self/non-self limits
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Percy, Edward Richard. "Corrected LM goodness-of-fit tests with applicaton to stock returns." Columbus, Ohio : Ohio State University, 2005. http://rave.ohiolink.edu/etdc/view?acc%5Fnum=osu1134416514.
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Meintières, Sophie. "Le rôle de l'apoptose dans les tests in vitro de clastogenèse : apport du modèle CTLL-2 / CTLL-2 Bcl2." Lille 2, 2002. http://www.theses.fr/2002LIL2P014.
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Oliveira, Karen Fantine Silva Souza de. "Os acidentes de trabalho e os valores humanos em operadores de uma f?brica de cal?ados." Universidade Federal do Rio Grande do Norte, 2004. http://repositorio.ufrn.br:8080/jspui/handle/123456789/17497.
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Previous issue date: 2004-09-13<br>The study present analyzes the relation between work accident and human values. It was developed with the sample of 156 operators of a factory, through to an application of structured questionnaires. The data were submitted to quantitative analyses (for example, analyses of frequency distributions, Chi-Square, test t). It was verified that 27 employees that filled out the questionnaires suffered work accidents. The results evidence that there aren?t significant differences between the people s values that suffered work accidents and those that did not suffer. The employees presented a hierarchy of different values comparing with the others Brazilian studies. It was observed that the work accidents varies for organizational sectors. So, we get the conclusion, the occurrence of the work accidents is not associated to the values, but they are probably associated to work conditions<br>O presente estudo analisa a rela??o entre os acidentes de trabalho e os valores humanos. Foi desenvolvido com uma amostra de 156 operadores de uma f?brica, atrav?s da aplica??o de question?rios estruturados. Os dados foram submetidos a an?lises quantitativas (por exemplo, an?lises das distribui??es de freq??ncia, teste t e qui-quadrado). Verificou-se que 27 funcion?rios que preencheram os question?rios sofreram acidentes de trabalho. Os resultados apontam que n?o h? diferen?as significativas entre os valores daqueles que sofreram acidentes e os que n?o sofreram. Os participantes apresentaram uma hierarquia de valores diferente de outras amostras pesquisadas nos Brasil. Constataram-se diferen?as de freq??ncia de acidentes por setores da empresa. Verificou-se, ent?o, que, a ocorr?ncia dos acidentes de trabalho n?o est? associada aos valores, mas mais provavelmente ?s condi??es de trabalho
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Novotná, Romana. "Zdanění alkoholických nápojů ve skandinávských zemích." Master's thesis, Vysoká škola ekonomická v Praze, 2014. http://www.nusl.cz/ntk/nusl-192702.
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The subject of this diploma thesis is to analyze the system of taxation of alcoholic beverages in the Scandinavian countries. The main aim of this thesis is to compare the taxation of alcoholic beverages in the Nordic countries with taxation in the rest of the European Union. The first part is theoretical and focuses on defining the concepts of tax competition, tax harmonization and coordination. It also includes harmonization of excise duties on alcoholic beverages based on the Directives of the European Union. The second part relates to the consumption of alcoholic beverages and deals with the historical aspect, changes in consumption patterns and the level of consumption in the Nordic countries. The third part deals with the taxation of alcoholic beverages, its development and differences in the Nordic countries compared with other countries of the European Union. In the second and the third part is carried out data analysis through statistical hypothesis testing and calculation of the coefficient of variation. The fourth part contains the evaluation. The thesis is peformed using descriptive, research, analytical and comparative methods and methods of mathematical statistics. The main outcome of this thesis is the finding that in all kinds of examined alcohol except spirits there is a different (for still wine and intermediate products even very different) level of taxation in the Nordic countries and other countries of the European Union.
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Holešovská, Pavla. "Analýza vývoje daně z přidané hodnoty v EU." Master's thesis, Vysoká škola ekonomická v Praze, 2013. http://www.nusl.cz/ntk/nusl-197618.
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This diploma thesis deals with an analysis of value added tax (VAT) development in the European Union from two points of view -- from the point of view of legislation development and from the point of view of development of true indicators. My goal was to find out, if the tax systems in the member states of the EU in the period from 1995 to 2010 became closer due to harmonization. In the first part, I try to explain the main principle of VAT and also how this tax works. In the following chapter I focus on the development of legislation concerning VAT in the EU from year 1995 to year 2013. Development of true figures (such as reduced VAT rates, standard rates, implicit tax rates on consumption, and value added tax-to-GDP ratio) is essential for achieving the goal. I devoted chapter three to this topic. In the last part of my work I find out (using statistical software Statgraphics), if the above mentioned figures became approximate or not.
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Comstedt, Wictor, and Robert Fredriksson. "Andrahandsmarknaden för småhuspriser i Sverige : En tidsserieanalys av olika makrovariablers påverkan och samvariation för åren 1996- 2006." Thesis, Uppsala University, Department of Economics, 2007. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-8158.
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<p>Syftet med uppsatsen är att analysera hur ett antal makrovariabler påverkar på och samverkar med priserna på småhus. Även hur variablerna reagerar på chocker sinsemellan studeras.</p><p>Tidsserieanalysen bygger på månadsdata från år 1996 fram till 2006, som innehåller alla försäljningar av småhusfastigheter i hela Sverige. Det kvalitetsindex som används för att analysera priserna är K/T- talet. För att studera skillnader, avseende samverkan och påverkan, regioner emellan görs en uppdelning av landet i regionerna Stockholm, Göteborg, Malmö, Glesbygd samt hela Sverige. För att testa olika makrovariablers påverkan på K/T- talen används Grangers kausalitets test. Resultaten av dessa test visar att K/T- talen påverkas på annorlunda sätt i de olika regionerna.</p><p>Fortsatt analys sker med estimering av en enkel vektorautoregressiv modell för varje region, där de tre endogena variabler K/T- tal för regionen, industriordrar och nybilsregistrering används. Sedan utförs impulsrespons chocker på de tre endogena variablerna. Den starkaste effekten som kan urskiljas av dessa chocker är att K/T- talen har en inverkan på hushållens förmögenhet och då även dess konsumtion.</p>
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Porcher, Jean-Marc. "Etude en culture de cellules du métabolisme et de la toxicité de la T-2 toxine informatisation d'un test de cytotoxicité /." Grenoble 2 : ANRT, 1988. http://catalogue.bnf.fr/ark:/12148/cb376176180.
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