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Artigos de revistas sobre o tema "Trachea"

Autor: Grafiati

Publicado: 4 de junho de 2021

Última modificação: 25 de julho de 2025

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1

Inozemtsev, E. O., I. S. Kurganskiy, S. A. Lepekhova, O. A. Goldberg, and E. G. Grigoriev. "Method of Formation of Tracheo-Tracheal Anastomosis with a Continuous Single-Row Suture in the Experiment." Acta Biomedica Scientifica 3, no. 6 (2019): 144–49. http://dx.doi.org/10.29413/abs.2018-3.6.21.

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The work is devoted toanew suture in the formation of tracheo-tracheal anastomosis. Despite the improvement of surgical technique in tracheal interventions, the number of postoperative complications (insufficiency and stenosis of anastomosis) remains high, with postoperative lethality reaching 18.2 %. The main problem is the lack of a unified point of view on the choice of the method of anastomosis, in particular, inclusion in the mucosal suture. Several variants of tracheo-tracheal anastomosis are suggested, but a large number of complications testify to the shortcomings of the methods used.T

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2

Zimmermann, Jeannette, Anna Brunner, Julius Underberg, and Simona Vincenti. "CT measurements of tracheal diameter and length in normocephalic cats." Journal of Feline Medicine and Surgery 25, no. 3 (2023): 1098612X2311585. http://dx.doi.org/10.1177/1098612x231158578.

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Objectives The aim of this study was to measure the tracheal dimensions of normocephalic cats using CT. Methods CT images of 15 client-owned normocephalic cats were retrospectively evaluated to measure the length of the feline trachea. Transverse and vertical inner diameters were measured in five different tracheal regions, and the cross-sectional area of the tracheal lumen was calculated for each point of measurement. Descriptive statistics were applied using a two-tailed t-test. Results The mean ± SD length of the trachea was 125.13 ± 14.41 mm. Male cats had significantly larger tracheas tha

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3

Darr, A., S. Mohamed, D. Eaton, and MS Kalkat. "Tracheo-oesophageal fistula in a patient with chronic sarcoidosis." Annals of The Royal College of Surgeons of England 97, no. 7 (2015): e100-e102. http://dx.doi.org/10.1308/003588415x14181254790446.

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Sarcoidosis is a common multisystem granulomatous condition of unknown aetiology, predominantly involving the respiratory system. Tracheal stenosis has been described but we believe that we present the first case of a tracheo-oesophageal fistula secondary to chronic sarcoidosis. A 57-year-old woman with sarcoidosis, a known tracheal stricture and a Polyflex® stent in situ presented with stridor. Bronchoscopy confirmed in-stent stenosis, by exuberant granulation tissue. The stent was removed and the granulation tissue was resected accordingly. Postoperatively, the patient was noticed to have an

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4

Lim, S., J. Jeong, HG Heng, et al. "Computed tomographic features of tracheal shapes and dimensions in awake dogs." Veterinární Medicína 63, No. 3 (2018): 131–36. http://dx.doi.org/10.17221/124/2017-vetmed.

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There are several reports in the veterinary literature on tracheal assessment; however, there is a lack of studies on the trachea in voluntarily breathing dogs. The aim of this study was to describe the natural shape of the trachea in awake dogs and to assess tracheal dimensions and the width-to-height ratio. Thoracic computed tomographic images of awake small breed dogs without any signs of respiratory malfunction (n = 19) were evaluated. Each trachea was categorised into one of four different shapes: circular, horseshoe, crescent or focal dorsal invagination. The circular shape was prominent

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5

Byanet, O., J. A. Bosha, and B. O. Onoja. "A Quantitative Study on the Trachea of the Red Sokoto (Maradi) Goat (Capra hircus)." Veterinary Medicine International 2014 (2014): 1–5. http://dx.doi.org/10.1155/2014/142715.

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The trachea forms the part of the conducting system which transports air from the external environment to the lungs. The aim of this study was to provide quantitative dimensions of the trachea of Red Sokoto goat (Capra hircus). Quantitative analysis was conducted on nine tracheas from goats (ages were ranged between eight months and three years) without sex variation in this study. The results showed that tracheas were extended from the cricoid cartilage of larynx to the hilus of the lungs, where they were divided into the right and left bronchi. They were structurally composed of the cartilag

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6

Kao, James, Christopher N. Fortner, Lynne H. Liu, Gary E. Shull, and Richard J. Paul. "Ablation of the SERCA3 gene alters epithelium-dependent relaxation in mouse tracheal smooth muscle." American Journal of Physiology-Lung Cellular and Molecular Physiology 277, no. 2 (1999): L264—L270. http://dx.doi.org/10.1152/ajplung.1999.277.2.l264.

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Sarcoplasmic/endoplasmic reticulum Ca2+-ATPase 3 (SERCA3), an isoform of the intracellular Ca2+ pump that has been shown to mediate endothelium-dependent relaxation of vascular smooth muscle, is also expressed in tracheal epithelium. To determine its possible role in regulation of airway mechanical function, we compared tracheal contractility in gene-targeted mice deficient in SERCA3 (SERCA3−) with that in wild-type tracheae. Cumulative addition of ACh elicited concentration-dependent increases in isometric force (ED50 = 2 μM, maximum force = 8 mN/mm2) that were identical in SERCA3− and wild-t

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7

Linkov, Gary, Arash Hanifi, Farzad Yousefi, et al. "Compositional Assessment of Human Tracheal Cartilage by Infrared Spectroscopy." Otolaryngology–Head and Neck Surgery 158, no. 4 (2018): 688–94. http://dx.doi.org/10.1177/0194599817752310.

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Objectives To assess the potential of infrared fiber-optic spectroscopy to evaluate the compositional properties of human tracheal cartilage. Study Design Laboratory-based study. Methods Twenty human cadaveric distal tracheas were harvested (age range 20-78 years; 6 females, 14 males) for compositional analysis. Histologic staining, Fourier transform infrared imaging spectroscopy data on collagen and proteoglycan (PG) content, and near-infrared (NIR) fiber-optic probe spectroscopic data that reflect protein and water content were evaluated. NIR fiber-optic probe data were also obtained from th

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8

Sotres-Vega, Avelina, Jaime Villalba-Caloca, Farid Ramirez-Zamora, Diana Pérez-Covarrubias, and J. Alfredo Santibáñez-Salgado. "Cryopreserved tracheal segments: a new tool for bench surgical training in thoracic surgery." Acta Cirurgica Brasileira 27, no. 8 (2012): 585–88. http://dx.doi.org/10.1590/s0102-86502012000800012.

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PURPOSE: To present a new low-cost high fidelity bench model of cryopreserved trachea that can be used to learn surgical skills from medical students to cardiothoracic surgery fellows. METHODS: Ten tracheas were harvested from ten non-trachea related research dogs at the moment of euthanasia. Each trachea was trimmed in six or seven rings segments. They were cryopreserved and stored during 60 days. The day programmed for surgical skills practice, they were thawed to room temperature. RESULTS: Forty segments have been used. After defrosting, all the segments kept their normal anatomic shape and

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9

Mikheev, Mikheev V., and Sergey N. Trushin. "A clinical case of successful treatment of complete abruption of the trachea from the larynx." I.P. Pavlov Russian Medical Biological Herald 29, no. 1 (2021): 117–24. http://dx.doi.org/10.23888/pavlovj2021291117-124.

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Tracheobronchial injuries as a consequence of chest blunt trauma are rare. Blunt traumas of the cervical part of the trachea are a rarer pathology presenting a serious diagnostic problem for a clinician. Traumas of the larynx and the trachea account for 40 to 80% of lethality. The tracheas cervical part is vulnerable despite that it is covered with the neck muscles, spine, clavicles, and mandible. In cut/stab wounds, the tracheas cervical part is often damaged together with the adjacent structures. In blunt trauma, under a direct action of a traumatizing agent, the mobile trachea displaces tow

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10

Махутов, Valeriy Makhutov, Скворцов, et al. "CIRCULAR RESECTION OF THE TRACHEA FOR CICATRICIAL STENOSIS." Бюллетень Восточно-Сибирского научного центра Сибирского отделения Российской академии медицинских наук 1, no. 4 (2016): 150–55. http://dx.doi.org/10.12737/23004.

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The primary interventions for trachea in the thoracic surgery units are performed for the treatment of cicatricial ste-nosis of the trachea. Circular resection of the trachea is one of the treatment procedures in this pathology. The benefit of this method as compared to the others is that the resection with tracheo-tracheal anastomosis allows a one-stage recovery of patient with this pathology.The first successful resection of the trachea was performed in the late 19th century, and since then this surgery tech-nique is constantly being improved. Several methods of suture placing in anastomosis

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11

Wangensteen, O. D., L. A. Schneider, S. C. Fahrenkrug, G. M. Brottman, and R. C. Maynard. "Tracheal epithelial permeability to nonelectrolytes: species differences." Journal of Applied Physiology 75, no. 2 (1993): 1009–18. http://dx.doi.org/10.1152/jappl.1993.75.2.1009.

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We developed a new excised tracheal preparation to measure the epithelial permeability of large lipid-insoluble nonelectrolytes and macromolecules. Tracheae were suspended vertically in a Ringer solution bath, and a solution containing labeled test solutes was positioned in the center of the tracheal segment, away from damaged ends. Permeability coefficients, calculated from solute fluxes into the bath, were constant for > or = 2 h at 37 degrees C, and no histological changes were observed. Measurements after epithelial removal with detergent indicate that in the intact trachea the epitheli

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12

Begis, D., C. Delpuech, P. Le Tallec, L. Loth, M. Thiriet, and M. Vidrascu. "A finite-element model of tracheal collapse." Journal of Applied Physiology 64, no. 4 (1988): 1359–68. http://dx.doi.org/10.1152/jappl.1988.64.4.1359.

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The trachea has been approximated by an appropriate finite-element model. The three-dimensional equilibrium problems set by the tracheal deformation under various stresses have been solved using a convenient augmented Lagrangian functional. The dimensions were obtained from human tracheae. Mechanical constants for the anatomic components were calculated from the stress-strain relationships. The compressive narrowing is essentially due to the invagination of the posterior membrane in the tracheal lumen for transmural pressures down to -7 kPa. A surface of contact between the membranous wall and

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13

Nimeri, Nuha, Haytham Ali, and Nazla Mahmoud. "Lethal severe congenital tracheal stenosis with tracheal ring complicating respiratory distress syndrome in an extremely premature infant: first reported case in Qatar with a literature review." BMJ Case Reports 13, no. 12 (2020): e236107. http://dx.doi.org/10.1136/bcr-2020-236107.

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In the context of prematurity, lethal congenital airways malforamtion can be masked by the symptoms of respiratory distress syndrome. A high index of suspicion is required. We present the case of a 28-week preterm infant, with atypical protracted respiratory insufficiency despite the escalation of mechanical ventilation. The possibility of airway obstruction was considered in view of severe chest retraction while on the mechanical ventilator. It was also difficult to pass suction catheters beyond a certain depth in the trachea; however, intubation of the upper trachea was accomplished twice wi

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14

Akopov, A. L., G. V. Papayan, S. D. Gorbunkov, et al. "Fluorescence imaging in evaluating the revascularization of heterotopically transplanted primate trachea segment." Russian Journal of Transplantology and Artificial Organs 22, no. 2 (2020): 80–85. http://dx.doi.org/10.15825/1995-1191-2020-2-80-85.

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Objective: to assess the potentials of using indocyanine green fluorescence angiography in evaluating revascularization of tissue-engineered construct that was obtained from the decellularized biological matrix of primate trachea, including using mesenchymal stem cells, after heterotopic tracheal allotransplantation. Material and methods. Tracheas were obtained from two male hamadryas baboons. After decellularization, 4 cm segments of tracheas were implanted under the lateral part of the latissimus dorsi in two healthy primates, one after recellularization with mesenchymal stem cells (animal 1

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15

Grubb, B. R., A. M. Paradiso, and R. C. Boucher. "Anomalies in ion transport in CF mouse tracheal epithelium." American Journal of Physiology-Cell Physiology 267, no. 1 (1994): C293—C300. http://dx.doi.org/10.1152/ajpcell.1994.267.1.c293.

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The cystic fibrosis (CF) mouse trachea has become a model for gene transfer. To characterize ion transport properties of tracheal epithelium from normal and CF mice, tracheas were excised, mounted in Ussing chambers, and basal properties and responses to pharmacological agents and/or ion substitution protocols measured. No difference in basal short-circuit (Isc) was observed between normal (29.1 +/- 3.8 muA/cm2, n = 21) and CF (34.7 +/- 4.5 muA/cm2, n = 16) tracheas. The relative contribution of Na+ transport to basal Isc was small (30-40%). Ionomycin stimulated large increases in Isc in both

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16

Lawrence, David A., Brittany Branson, Isabel Oliva, and Ami Rubinowitz. "The Wonderful World of the Windpipe: A Review of Central Airway Anatomy and Pathology." Canadian Association of Radiologists Journal 66, no. 1 (2015): 30–43. http://dx.doi.org/10.1016/j.carj.2014.08.003.

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A variety of pathologic processes can involve the central airways. Abnormalities may either diffusely or focally involve the tracheal or mainstem bronchial walls. Diseases that diffusely involve the tracheal wall can be subclassified as sparing the membranous trachea or circumferentially involving the tracheal wall. Focal diseases of the trachea and mainstem bronchi include benign and malignant causes. Additionally, congenital and acquired morphologic abnormalities of the trachea will be reviewed.

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17

Perpina, M., J. Cortijo, E. Fornas, M. Palau, JL Ortiz, and E. Morcillo. "Hyperreactivity and 45Ca movements in sensitized guinea-pig tracheal muscle." European Respiratory Journal 4, no. 4 (1991): 450–57. http://dx.doi.org/10.1183/09031936.93.04040450.

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Responses to KCl and histamine and 45Ca movements were studied in trachea from normal and actively sensitized guinea-pigs. Sensitized tracheas were hyperresponsive and hypersensitive to KCl and histamine. 45Ca uptake experiments show that sensitized tracheal muscle behaves as normal except that the uptake of 45Ca in low concentration (0.03 mM) Ca2+ solution was higher and the number of binding sites for the high affinity component of 45Ca uptake (as estimated by Scatchard-coordinate plot) was augmented. Additionally, in sensitized tracheal muscle, incubation in low (0.03 mM) Ca2+ solution foll

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18

Deng, Mingming, Mengchan Wang, Qin Zhang, et al. "Point-of-care ultrasound-guided submucosal paclitaxel injection in tracheal stenosis model." Journal of Translational Internal Medicine 11, no. 1 (2023): 70–80. http://dx.doi.org/10.2478/jtim-2022-0044.

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Abstract Background and Objectives Transcutaneous point-of-care ultrasound (POCUS) is a good tool to monitor the trachea in many clinical practices. The aim of our study is to verify the feasibility of POCUS-guided submucosal injection as a potential drug delivery method for the treatment of tracheal stenosis. Materials and methods The inner wall of the trachea was monitored via a bronchoscope during the POCUS-guided submucosal injection of methylene blue in fresh ex vivo porcine trachea to evaluate the distribution of methylene blue. The feasibility and eficacy of POCUS-guided submucosal inje

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19

Mazzone, Stuart B., and Alice E. McGovern. "Innervation of tracheal parasympathetic ganglia by esophageal cholinergic neurons: evidence from anatomic and functional studies in guinea pigs." American Journal of Physiology-Lung Cellular and Molecular Physiology 298, no. 3 (2010): L404—L416. http://dx.doi.org/10.1152/ajplung.00166.2009.

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In the present study, we describe a subset of nerve fibers, characterized by their immunoreactivity for the calcium-binding protein calretinin, that are densely and selectively associated with cholinergic postganglionic neurons in the guinea pig tracheal ganglia. Retrograde neuronal tracing with cholera toxin B, combined with immunohistochemical analyses, showed that these nerve fibers do not originate from sensory neurons in the nodose, jugular, or dorsal root ganglia or from motor neurons in the nucleus ambiguus, dorsal motor nucleus of the vagus nerve, spinal cord, stellate ganglia, or supe

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20

R, Shwethapriya, Anuradha Nittala, and Anitha Shenoy. "Tracheo-oesophageal fistula - A disastrous complication of endotracheal intubation!" Indian Journal of Respiratory Care 02, no. 01 (2022): 238–40. http://dx.doi.org/10.5005/jp-journals-11010-02112.

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A 28-year old man required invasive mechanical ventilation in view of organophosphorus poisoning in a peripheral hospital. His trachea was extubated ten days later following which he presented with dysphagia, voice change, burping, fever and cough. He was referred to our hospital for further management. His barium swallow radiograph showed a large tracheo-oesophageal fistula. Therefore, he was scheduled for oesophageal transection and colonic transposition. Following induction of anaesthesia, despite easy laryngoscopy view (Cormack Lehane grade 1), the tracheal intubation was found to be diffi

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21

Rosen, Frederick S., Anna M. Pou, and William L. Buford. "Tracheal Resection with Primary Anastomosis in Cadavers: The Effects of Releasing Maneuvers and Length of Tracheal Resection on Tension." Annals of Otology, Rhinology & Laryngology 112, no. 10 (2003): 869–76. http://dx.doi.org/10.1177/000348940311201008.

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To determine the relationships among length of trachea resected, total tracheal length, and anastomotic tension when using various release maneuvers, we studied 10 adult human cadavers: 5 male and 5 female. The trachea was transected between rings 2 and 3. Precision, handheld spring tensiometers (Geneva Gage, LLC) were used to measure the tension required to approximate, and then overlap, the proximal segment relative to the distal segment, and the distal segment relative to the proximal segment after these maneuvers: no release, blunt dissection, neck flexion, suprahyoid release (SHR) without

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22

Wimmer-Greinecker, G., Ch Gross, R. Mair, U. Klima, W. Harringer, and P. Brücke. "Coronary Disease and Tracheal Stenosis with Tracheo-Oesophageal Fistula: A Combined Surgical Procedure." Cardiovascular Surgery 2, no. 2 (1994): 226–28. http://dx.doi.org/10.1177/096721099400200217.

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A patient with coronary disease class III of the New York Heart Association and tracheal stenosis with a tracheo-oesophageal fistula, which developed after long-term intubation, is described. As both conditions were symptomatic, an aortocoronary double bypass was combined with resection of the trachea and closure of the fistula. Postoperative recovery was uneventful and the patient is symptom-free after 3 years.

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23

Goddard, Catharine A., Martin J. Evans, and William H. Colledge. "Genistein activates CFTR-mediated Cl−secretion in the murine trachea and colon." American Journal of Physiology-Cell Physiology 279, no. 2 (2000): C383—C392. http://dx.doi.org/10.1152/ajpcell.2000.279.2.c383.

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The action of the isoflavone genistein on the cystic fibrosis transmembrane conductance regulator (CFTR) has been studied in many cell systems but not in intact murine tissues. We have investigated the action of genistein on murine tissues from normal and cystic fibrosis (CF) mice. Genistein increased the short-circuit current ( I sc) in tracheal (16.4 ± 2.8 μA/cm2) and colonic (40.0 ± 4.4 μA/cm2) epithelia of wild-type mice. This increase was inhibited by furosemide, diphenylamine-2-carboxylate, and glibenclamide, but not by DIDS. In contrast, genistein produced no significant change in the I

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Yoshimura, Takaaki, Noriyo Colley, Shunsuke Komizunai, et al. "Construction of a detachable artificial trachea model for three age groups for use in an endotracheal suctioning training environment simulator." PLOS ONE 16, no. 3 (2021): e0249010. http://dx.doi.org/10.1371/journal.pone.0249010.

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Tracheal suctioning is an important procedure to maintain airway patency by removing secretions. Today, suctioning operators include not only medical staff, but also family caregivers. The use of a simulation system has been noted to be the most effective way to learn the tracheal suctioning technique for operators. While the size of the trachea varies across different age groups, the artificial trachea model in the simulation system has only one fixed model. Thus, this study aimed to construct multiple removable trachea models according to different age groups. We enrolled 20 patients who had

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Grace, R. F. "Spontaneous Respiration via an Open Trachea for Resection of a High Tracheal Stenosis in a Child." Anaesthesia and Intensive Care 30, no. 4 (2002): 502–4. http://dx.doi.org/10.1177/0310057x0203000420.

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The successful management of tracheal stenosis requires compromise between the competing interests of the surgical and anaesthetic teams and the resources available. A seven-year-old girl with marked tracheal stenosis was successfully managed spontaneously breathing via an open trachea and a laryngeal mask. Anaesthesia was maintained by propofol infusion. When the trachea was opened, supplemental oxygen was administered via a modified cholangiocatheter placed into the distal segment. At no point was the trachea intubated.

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Wycherly, Benjamin, Sonya Malekzadeh, Matthew Kirk Steehler, Burke Kevin, and Bhaskar Kallakury. "R453 – Cryoballoon Dilation of Tracheal Stenosis." Otolaryngology–Head and Neck Surgery 139, no. 2_suppl (2008): P196—P197. http://dx.doi.org/10.1016/j.otohns.2008.05.610.

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Problem The endoscopic management of tracheal stenosis remains ineffective, despite advances in dilation and resection techniques. The vascular literature reveals improved patency rates of stenosis with cryodilation compared to balloon angioplasty. The proposed mechanism is a decrease in collagen deposition with cryotherapy. Similarly, tracheal cryotherapy maintains the cartilaginous framework of the airway while minimizing collagen deposition. The objective of this study is to compare collagen deposition in tracheal injuries dilated with room temperature versus subfreezing temperature balloon

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Lee, Hwa-Yong, and Jin Woo Lee. "Current Status and Future Outlook of Additive Manufacturing Technologies for the Reconstruction of the Trachea." Journal of Functional Biomaterials 14, no. 4 (2023): 196. http://dx.doi.org/10.3390/jfb14040196.

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Tracheal stenosis and defects occur congenitally and in patients who have undergone tracheal intubation and tracheostomy due to long-term intensive care. Such issues may also be observed during tracheal removal during malignant head and neck tumor resection. However, to date, no treatment method has been identified that can simultaneously restore the appearance of the tracheal skeleton while maintaining respiratory function in patients with tracheal defects. Therefore, there is an urgent need to develop a method that can maintain tracheal function while simultaneously reconstructing the skelet

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Manolakis, Al, P. Bordei, C. Dina, and D. M. Iliescu. "Peculiar case of branching of the trachea together with both, main and lobar, bronchi into a fetal lung." ARS Medica Tomitana 21, no. 2 (2015): 112–15. http://dx.doi.org/10.1515/arsm-2015-0030.

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Abstract Using as study method the injection of plastic followed by corrosion, we described, on an 8 months fetal lung, a particular branching pattern of the right bronchial tree were the superior lobar bronchus arise on the right side of the trachea, at 4.1 cm cranial to tracheal bifurcation. Other features of tracheo-bronchial branching encountered in this case: the level and tracheal bifurcation site and origin and the trajectory of the main bronchi, the middle lobar bronchi of the right lung and apical bronchus of the inferior lobar bronchi. To these peculiarities of the tracheo-bronchial

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Hirano, T., C. Konaka, S. Okada, et al. "Endoscopic Diagnosis and Treatment of a Case of Respiratory Papillomatosis." Diagnostic and Therapeutic Endoscopy 3, no. 3 (1997): 183–87. http://dx.doi.org/10.1155/dte.3.183.

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Respiratory papilloma is a rare lesion that arises in the larynx, trachea and bronchus. We describe a patient with laryngeal papilloma that spread to the trachea and which was effectively treated by Nd-YAG laser. Two years after the initial treatments of the laryngeal and tracheal papillomas, a recurrent lesion (solitary papilloma) was observed on the membranous portion of the trachea. We examined the recurrent lesion by bronchoscopy including bronchoscopic ultrasound (US), helical computed tomography (CT) and tracheal biopsies. Respiratory papillomatosis sometimes shows either malignant trans

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Kimura, Akari, Koji Araki, Yasushi Satoh, et al. "Inhibition of extracellular signal-regulated kinase pathway suppresses tracheal stenosis in a novel mouse model." PLOS ONE 16, no. 9 (2021): e0256127. http://dx.doi.org/10.1371/journal.pone.0256127.

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Tracheal stenosis is a refractory and recurrent disease induced by excessive cell proliferation within the restricted tracheal space. We investigated the role of extracellular signal-regulated kinase (ERK), which mediates a broad range of intracellular signal transduction processes in tracheal stenosis and the therapeutic effect of the MEK inhibitor which is the upstream kinase of ERK. We histologically analyzed cauterized tracheas to evaluate stenosis using a tracheal stenosis mouse model. Using Western blot, we analyzed the phosphorylation rate of ERK1/2 after cauterization with or without M

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Drobyazgin, E. A., and Yu V. Chikinev. "Stenting of the trachea with cicatricial stenosis, immediate and long-term results." Filin’s Clinical endoscopy 64, no. 3 (2024): 4–10. http://dx.doi.org/10.31146/2415-7813-endo-64-3-4-10.

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The aim of study Evaluation of the results of stenting in the treatment of cicatricial stenosis of the trachea. Materials and methods During the period from 1995 to 2023, 154 patients with cicatricial stenosis of the trachea were treated (men - 109 (70.77%), women - 45 (29.22%). The age of the patients ranged from 15 to 83 years. Patients of working age (from 20 to 50 years old) were 102 (66, 23%). The causes of stenosis were: tracheostomy and / or prolonged mechanical lung ventilation through a tracheostomy tube (106-68.83%), mechanical ventilation through the orotracheal tube (38-24.67%), in

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Carr, E. R. M., and E. Benjamin. "In vitro study investigating post neck surgery haematoma airway obstruction." Journal of Laryngology & Otology 123, no. 6 (2008): 662–65. http://dx.doi.org/10.1017/s0022215108003423.

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AbstractObjectives:To investigate whether the possible pressure produced by a haematoma in the neck would be sufficient to directly compress the trachea to the point of airway obstruction.Study design:In vitro study.Methods:Varying pressures were applied over the second and third cartilaginous rings of 10 pig tracheas in vitro and the anterior–posterior compression was measured.Results:At pressures of 257 mmHg, equivalent to the maximum possible pressure in the neck (i.e. systolic blood pressure), there was an average compression of 20.8 per cent of the original anterior–posterior tracheal dia

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Paramita, Swandari, Emil Bachtiar Moerad, Sjarif Ismail, and Eva Marliana. "Antiasthmatic effect of Curcuma aeruginosa extract on isolated organ of the trachea." F1000Research 7 (November 15, 2018): 1799. http://dx.doi.org/10.12688/f1000research.16416.1.

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Background:Asthma is a major health problem worldwide. Antiasthma drugs have side effects and can be expensive. It is important to develop antiasthma drugs from medicinal plants that have fewer side effects and are cheaper. One of the medicinal plants used for antiasthma treatment comes fromCurcuma aeruginosa(Zingiberaceaefamily). The aim of the research is to examine spasmolytic activity of ethanol extract ofC. aeruginosaon isolated guinea pig tracheas to determine the antiasthma effects.Methods:The spasmolytic activity ofC. aeruginosaextracts was tested in separated organs of guinea pig trac

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Bedolla, Carlos N., Catherine Rauschendorfer, Drew B. Havard, et al. "Spectral Reflectance as a Unique Tissue Identifier in Healthy Humans and Inhalation Injury Subjects." Sensors 22, no. 9 (2022): 3377. http://dx.doi.org/10.3390/s22093377.

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Tracheal intubation is the preferred method of airway management, a common emergency trauma medicine problem. Currently, methods for confirming tracheal tube placement are lacking, and we propose a novel technology, spectral reflectance, which may be incorporated into the tracheal tube for verification of placement. Previous work demonstrated a unique spectral profile in the trachea, which allowed differentiation from esophageal tissue in ex vivo swine, in vivo swine, and human cadavers. The goal of this study is to determine if spectral reflectance can differentiate between trachea and other

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Bottasso-Arias, Natalia, Lauren Leesman, Kaulini Burra, et al. "BMP4 and Wnt signaling interact to promote mouse tracheal mesenchyme morphogenesis." American Journal of Physiology-Lung Cellular and Molecular Physiology 322, no. 2 (2022): L224—L242. http://dx.doi.org/10.1152/ajplung.00255.2021.

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Tracheobronchomalacia and complete tracheal rings are congenital malformations of the trachea associated with morbidity and mortality for which the etiology remains poorly understood. Epithelial expression of Wls (a cargo receptor mediating Wnt ligand secretion) by tracheal cells is essential for patterning the embryonic mouse trachea’s cartilage and muscle. RNA sequencing indicated that Wls differentially modulated the expression of BMP signaling molecules. We tested whether BMP signaling, induced by epithelial Wnt ligands, mediates cartilage formation. Deletion of Bmp4 from respiratory tract

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Pavlovic, D., M. Fournier, M. Aubier, and R. Pariente. "Epithelial vs. serosal stimulation of tracheal muscle: role of epithelium." Journal of Applied Physiology 67, no. 6 (1989): 2522–26. http://dx.doi.org/10.1152/jappl.1989.67.6.2522.

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There is evidence implying an active role of airway epithelium in the modulation of bronchomotor tone. To study this phenomenon, we designed an in vitro system allowing pharmacological stimulation of either the inside or outside of the airway lumen. Rat tracheas were excised, cannulated, and their inside and outside perfused independently with Krebs solution. Two hooks were inserted through opposite sides of the tracheal wall, the lower one was attached to a fixed point, while the upper one was connected to a force transducer. Isometric contractions of the tracheal muscle were elicited by carb

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Coon, Robert L., Patrick J. Mueller, and Philip S. Clifford. "Functional anatomy of the vagal innervation of the cervical trachea of the dog." Journal of Applied Physiology 89, no. 1 (2000): 139–42. http://dx.doi.org/10.1152/jappl.2000.89.1.139.

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The canine cervical trachea has been used for numerous studies regarding the neural control of tracheal smooth muscle. The purpose of the present study was to determine whether there is lateral dominance by either the left or right vagal innervation of the canine cervical trachea. In anesthetized dogs, pressure in the cuff of the endotracheal tube was used as an index of smooth muscle tone in the trachea. After establishment of tracheal tone, as indicated by increased cuff pressure, either the right or left vagus nerve was sectioned followed by section of the contralateral vagus. Sectioning th

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Drobyazgin, E. A., Yu V. Chikinev, I. E. Sudovykh, and I. V. Peshkova. "Endoscopic interventions in tumor of trachea." Grekov's Bulletin of Surgery 176, no. 4 (2017): 18–21. http://dx.doi.org/10.24884/0042-4625-2017-176-4-18-21.

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OBJECTIVE. The authors assessed possibilities of endoscopic methods for restoration and maintenance of trachea patency. MATERIAL AND METHODS. The article presents results of endoscopic treatment of 26 patients with trachea tumors. Tumor lesions of trachea was the main cause of contraction (primary tracheal cancer had 9 patients; esophageal cancer with invasion inside trachea - 5 patients; relapse of trachea cancer - 1case; relapse of larynx cancer - 1 case; lung cancer with invasion inside trachea - 3 cases; thyroid cancer - 2 patients). RESULTS. Endoscopic interventions were applied in order

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Callan, Edward, Eugene J. Karandy, and Raymond L. Hilsinger. "“Saber-Sheath” Trachea." Annals of Otology, Rhinology & Laryngology 97, no. 5 (1988): 512–15. http://dx.doi.org/10.1177/000348948809700514.

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Narrowing of the intrathoracic trachea in the coronal plane with anteroposterior lengthening is characteristic of the saber-sheath trachea deformity. This structural disorder is strongly associated with chronic obstructive pulmonary disease and may be related to chronic bronchitis. Although lateral compression suggests weakening and collapse, the supporting tracheal cartilage is usually thickened and densely calcified. We present a patient who was discharged after uneventful total laryngectomy but later complained of increasing airway obstruction from crusted secretions, resulting in visits to

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Kloek, Joris, Ingrid van Ark, Nanne Bloksma, Fred De Clerck, Frans P. Nijkamp, and Gert Folkerts. "Glutathione and other low-molecular-weight thiols relax guinea pig trachea ex vivo: interactions with nitric oxide?" American Journal of Physiology-Lung Cellular and Molecular Physiology 283, no. 2 (2002): L403—L408. http://dx.doi.org/10.1152/ajplung.00376.2001.

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The aim of this study was to determine the effects of glutathione (GSH) on trachea smooth muscle tension in view of previously reported interactions between GSH and nitric oxide (NO) (Gaston B. Biochim Biophys Acta 1411: 323–333, 1999; Kelm M. Biochim Biophys Acta 1411: 273–289, 1999; and Kharitonov VG, Sundquist AR, and Sharma VS. J Biol Chem 270: 28158–28164, 1995) and the high (millimolar) concentrations of GSH in trachea epithelium (Rahman I, Li XY, Donaldson K, Harrison DJ, and MacNee W. Am J Physiol Lung Cell Mol Physiol 269: L285–L292, 1995). GSH and other thiols (1.0–10 mM) dose depend

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Ševčíková, Marieta K., Karol Ševčík, Mária Figurová, et al. "Retrospective analysis of tracheal hypoplasia in brachycephalic and non-brachycephalic dogs: Inter- and intra-observer agreement of measurements." Acta Veterinaria Hungarica 70, no. 3 (2022): 192–200. http://dx.doi.org/10.1556/004.2022.00018.

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Abstract This retrospective study was undertaken on the records of intraluminal diameter of the trachea in 185 dogs, in which hypoplasia of the trachea had been suspected. The relative size of the trachea was measured using the tracheal diameter (TD), thoracic inlet distance (TI), thoracic tracheal diameter (TT) and the width of the third rib (3R), expressed as ratios TD:TI and TT:3R. Thirty-five dogs were diagnosed as having tracheal hypoplasia. Bulldogs and non-bulldog brachycephalic dogs had significantly smaller measured trachea diameters compared to the predicted values calculated on the

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Ikeda, Masakazu, Mitsuyoshi Imaizumi, Susumu Yoshie, et al. "Implantation of Induced Pluripotent Stem Cell–Derived Tracheal Epithelial Cells." Annals of Otology, Rhinology & Laryngology 126, no. 7 (2017): 517–24. http://dx.doi.org/10.1177/0003489417713504.

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Objectives: Compared with using autologous tissue, the use of artificial materials in the regeneration of tracheal defects is minimally invasive. However, this technique requires early epithelialization on the inner side of the artificial trachea. After differentiation from induced pluripotent stem cells (iPSCs), tracheal epithelial tissues may be used to produce artificial tracheas. Herein, we aimed to demonstrate that after differentiation from fluorescent protein-labeled iPSCs, tracheal epithelial tissues survived in nude rats with tracheal defects. Methods: Red fluorescent tdTomato protein

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Pandey, G., B. Thakur, and M. Devkota. "Adenoid cystic carcinoma in trachea: A rare presentation." Journal of Pathology of Nepal 6, no. 11 (2016): 965–67. http://dx.doi.org/10.3126/jpn.v6i11.15684.

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Primary tracheal tumors are rare. Adenoid cystic carcinoma of trachea is even rarer. It occurs as a polypoidal mass in trachea presenting with dyspnea and respiratory distress due to tracheobronchial obstruction. We report a case of young male presenting with dyspnea for some time. CT scan revealed mass in trachea obliterating its lumen. Histopathological examination conirmed the diagnosis.

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Kato, I., K. Uesugi, M. Kikuchihara, et al. "Tracheostomy—The horizontal tracheal incision." Journal of Laryngology & Otology 104, no. 4 (1990): 322–25. http://dx.doi.org/10.1017/s0022215100112599.

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AbstractThe complication rate after emergency tracheostomy is two to five times greater than after elective procedures. One of the main causes of the high risk of complications in emergency tracheostomy appears to be the amount of time required to open the trachea. Therefore, simple and fast procedures are mandatory. We have developed a new procedure as follows: A horizontal skin incision is performed. Strap muscles are dissected and retracted laterally. A transverse cut between tracheal rings below the thyroid isthmus is performed up to membranous portion of the trachea. The cut ends of the t

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Salihov, O. X., S. M. Halimov, and KH R. Tukhtaev. "SIMULTANEOUS ELIMINATION OF EXTENSIVE TRACHEAL DEFECTS: PREVENTION OF RESTENOSIS." SCIENCE AND EDUCATION 1, no. 3 (2024): 274–88. https://doi.org/10.25005/3078-5022-2024-1-3-274-288.

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The article presents a clinical observation of surgical treatment of a patient with cicatricial stenosis of the larynx and trachea after tracheostomy. The patient underwent laryngotracheoplasty with the introduction of a T–shaped tube and an unsuccessful attempt to eliminate the tracheal defect using an autotransplantat. Extensive tracheal defects were eliminated by a one–stage plastic surgery method using a tubular silicone endoprosthesis. Keywords: laryngotracheoplasty, cicatricial stenosis of the trachea, elimination of the tracheal defect

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Ter-Ovanesov, M. D., A. A. Aksarin, and S. M. Kopeyka. "A case of tracheal chondrosarcoma." Siberian journal of oncology 24, no. 1 (2025): 164–73. https://doi.org/10.21294/1814-4861-2025-24-1-164-173.

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Background. Chondrosarcoma of the trachea is an extremely rare malignant tumor, accounting for only 0.1 % of all tracheal tumors. It is believed that chondrosarcoma arises from malignant degeneration in mesenchymal pluripotent cells of cartilage tissue, ossified cartilage, and enchondromas. Chondrosarcoma of the trachea is the least-studied tumor, with only 35 cases described in the literature from 1959 to 2020. Surgery with R0 resection remains the gold standard treatment of tracheal chondrosarcoma. The median age of patients at the time of diagnosis was 68 years, and 91 % were male. The most

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Philippe, Grégory, Nicolas Pichon, Justine Lerat, Jean Bernard Amiel, Marc Clavel, and Muriel Mathonnet. "Successful Treatment of Anterior Tracheal Necrosis after Total Thyroidectomy Using Vacuum-Assisted Closure Therapy." Critical Care Research and Practice 2012 (2012): 1–4. http://dx.doi.org/10.1155/2012/252719.

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Total thyroidectomy involving the adjacent structures of the trachea can cause tracheal damage such as early tracheal necrosis. The authors describe the first case of anterior tracheal necrosis following total thyroidectomy treated using vacuum-assisted closure device. After two weeks of VAC therapy, there was no evidence of ongoing infection and the trachea was partially closed around a tracheotomy cannula, removed after 3 months. The use of a VAC therapy to reduce and close the tracheal rent and to create a rapid granulation tissue over tracheal structure appeared as a good opportunity after

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Trigaux, J. P., G. Hermes, P. Dubois, B. Van Beers, L. Delaunois, and J. Jamart. "CT of Saber-Sheath Trachea." Acta Radiologica 35, no. 3 (1994): 247–50. http://dx.doi.org/10.1177/028418519403500310.

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The diagnosis of saber-sheath trachea is easy at CT due to its cross-sectional imaging, but the significance of this CT sign has not been evaluated in the diagnosis of chronic obstructive pulmonary disease (COPD). Various signs of COPD were compared between a series of 20 patients with a saber-sheath trachea at CT (tracheal index <66%) and a group of 20 pneumologic control patients without saber-sheath trachea (tracheal index ≥70%). These signs included clinical and standard radiographic indices of COPD, sternum-spine distance and 3 functional tests of COPD: forced expiratory volume in one

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Wei, Yi, Xiao-Lin Zhou, Tai-Hang Liu, et al. "A Matrix Metalloproteinase Mediates Tracheal Development in Bombyx mori." International Journal of Molecular Sciences 22, no. 11 (2021): 5618. http://dx.doi.org/10.3390/ijms22115618.

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The trachea of insects is a tubular epithelia tissue that transports oxygen and other gases. It serves as a useful model for the studying of the cellular and molecular events involved in epithelial tube formation. Almost all of the extracellular matrix can be degraded by Matrix metalloproteinases (MMPs), which is closely related to the processes of development and regeneration. The regulation of trachea by MMPs is roughly known in previous studies, but the detailed regulation mechanism and involved gene function are not fully explored. In this article, we found MMP1 expressed highly during tra

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Brown, I. G., P. M. Webster, N. Zamel, and V. Hoffstein. "Changes in tracheal cross-sectional area during Mueller and Valsalva maneuvers in humans." Journal of Applied Physiology 60, no. 6 (1986): 1865–70. http://dx.doi.org/10.1152/jappl.1986.60.6.1865.

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Pressure-area behavior of the excised trachea is well documented, but little is known of tracheal compliance in vivo. Extratracheal tissue pressures are not directly measurable, but transmural pressure for the intrathoracic trachea is inferred from intra-airway and pleural pressure differences. Extramural pressure of the cervical trachea is assumed to be atmospheric. The difference in transmural pressure between the intra- and extrathoracic tracheal segments should be exaggerated during Mueller and Valsalva maneuvers. We used the acoustic reflection technique to measure tracheal areas above an

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