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Artykuły w czasopismach na temat "Basigin receptor"

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Chen, Li, Jiajia Bi, Masaaki Nakai та ін. "Expression of basigin in reproductive tissues of estrogen receptor-α or -β null mice". REPRODUCTION 139, № 6 (2010): 1057–66. http://dx.doi.org/10.1530/rep-10-0069.

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Basigin plays important roles in both male and female reproduction because basigin (Bsg) null male and female mice are infertile. The aim of the present study was to determine whether basigin expression in reproductive organs requires estrogen receptor-α (ESR1, ERα) or -β (ESR2, ERβ). Expression of basigin protein in the testis, ovary, and male and female reproductive tracts was studied in adult wild-type (WT),Esr1-null (αERKO), andEsr2-null (βERKO) mice by immunohistochemistry and immunoblotting. Basigin mRNA levels in ovary and uterus were examined by quantitative RT-PCR. In females, basigin
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King, Nadine R., Catarina Martins Freire, Jawida Touhami, Marc Sitbon, Ashley M. Toye, and Timothy J. Satchwell. "Basigin mediation of Plasmodium falciparum red blood cell invasion does not require its transmembrane domain or interaction with monocarboxylate transporter 1." PLOS Pathogens 20, no. 2 (2024): e1011989. http://dx.doi.org/10.1371/journal.ppat.1011989.

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Plasmodium falciparum invasion of the red blood cell is reliant upon the essential interaction of PfRh5 with the host receptor protein basigin. Basigin exists as part of one or more multiprotein complexes, most notably through interaction with the monocarboxylate transporter MCT1. However, the potential requirement for basigin association with MCT1 and the wider role of basigin host membrane context and lateral protein associations during merozoite invasion has not been established. Using genetically manipulated in vitro derived reticulocytes, we demonstrate the ability to uncouple basigin ect
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Belton, Robert J., Li Chen, Fernando S. Mesquita, and Romana A. Nowak. "Basigin-2 Is a Cell Surface Receptor for Soluble Basigin Ligand." Journal of Biological Chemistry 283, no. 26 (2008): 17805–14. http://dx.doi.org/10.1074/jbc.m801876200.

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Mygind, Kasper J., Denise Nikodemus, Sebastian Gnosa та ін. "ADAM12-Generated Basigin Ectodomain Binds β1 Integrin and Enhances the Expression of Cancer-Related Extracellular Matrix Proteins". International Journal of Molecular Sciences 25, № 11 (2024): 5871. http://dx.doi.org/10.3390/ijms25115871.

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Desmoplasia is a common feature of aggressive cancers, driven by a complex interplay of protein production and degradation. Basigin is a type 1 integral membrane receptor secreted in exosomes or released by ectodomain shedding from the cell surface. Given that soluble basigin is increased in the circulation of patients with a poor cancer prognosis, we explored the putative role of the ADAM12-generated basigin ectodomain in cancer progression. We show that recombinant basigin ectodomain binds β1 integrin and stimulates gelatin degradation and the migration of cancer cells in a matrix metallopro
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Zenonos, Zenon A., Sara K. Dummler, Nicole Müller-Sienerth, et al. "Basigin is a druggable target for host-oriented antimalarial interventions." Journal of Experimental Medicine 212, no. 8 (2015): 1145–51. http://dx.doi.org/10.1084/jem.20150032.

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Plasmodium falciparum is the parasite responsible for the most lethal form of malaria, an infectious disease that causes a large proportion of childhood deaths and poses a significant barrier to socioeconomic development in many countries. Although antimalarial drugs exist, the repeated emergence and spread of drug-resistant parasites limit their useful lifespan. An alternative strategy that could limit the evolution of drug-resistant parasites is to target host factors that are essential and universally required for parasite growth. Host-targeted therapeutics have been successfully applied in
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Le Guennec, Loic, Zoé Virion, Haniaa Bouzinba-Ségard, et al. "Receptor recognition by meningococcal type IV pili relies on a specific complex N-glycan." Proceedings of the National Academy of Sciences 117, no. 5 (2020): 2606–12. http://dx.doi.org/10.1073/pnas.1919567117.

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Bacterial infections are frequently based on the binding of lectin-like adhesins to specific glycan determinants exposed on host cell receptors. These interactions confer species-specific recognition and tropism for particular host tissues and represent attractive antibacterial targets. However, the wide structural diversity of carbohydrates hampers the characterization of specific glycan determinants. Here, we characterized the receptor recognition of type IV pili (Tfp), a key adhesive factor present in numerous bacterial pathogens, using Neisseria meningitidis as a model organism. We found t
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Drzymała, Adam. "The Functions of SARS-CoV-2 Receptors in Diabetes-Related Severe COVID-19." International Journal of Molecular Sciences 25, no. 17 (2024): 9635. http://dx.doi.org/10.3390/ijms25179635.

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Angiotensin-converting enzyme 2 (ACE2) is considered a severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) receptor of high importance, but due to its non-ubiquitous expression, studies of other proteins that may participate in virus internalisation have been undertaken. To date, many alternative receptors have been discovered. Their functioning may provide an explanation for some of the events observed in severe COVID-19 that cannot be directly explained by the model in which ACE2 constitutes the central point of infection. Diabetes mellitus type 2 (T2D) can induce severe COVID-19 de
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Crosnier, Cécile, Leyla Y. Bustamante, S. Josefin Bartholdson, et al. "Basigin is a receptor essential for erythrocyte invasion by Plasmodium falciparum." Nature 480, no. 7378 (2011): 534–37. http://dx.doi.org/10.1038/nature10606.

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Patarroyo, Manuel Alfonso, Jessica Molina-Franky, Marcela Gómez, Gabriela Arévalo-Pinzón, and Manuel Elkin Patarroyo. "Hotspots in Plasmodium and RBC Receptor-Ligand Interactions: Key Pieces for Inhibiting Malarial Parasite Invasion." International Journal of Molecular Sciences 21, no. 13 (2020): 4729. http://dx.doi.org/10.3390/ijms21134729.

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Protein-protein interactions (IPP) play an essential role in practically all biological processes, including those related to microorganism invasion of their host cells. It has been found that a broad repertoire of receptor-ligand interactions takes place in the binding interphase with host cells in malaria, these being vital interactions for successful parasite invasion. Several trials have been conducted for elucidating the molecular interface of interactions between some Plasmodium falciparum and Plasmodium vivax antigens with receptors on erythrocytes and/or reticulocytes. Structural infor
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Luddi, Alice, Francesca Paola Luongo, Filippo Dragoni, et al. "Cellular and Molecular Mechanisms of In Vivo and In Vitro SARS-CoV-2 Infection: A Lesson from Human Sperm." Cells 11, no. 17 (2022): 2631. http://dx.doi.org/10.3390/cells11172631.

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Despite the major target of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), the causative agent of COVID-19, being the respiratory system, clinical evidence suggests that the male reproductive system may represent another viral target organ. Revealing the effect of SARS-CoV-2 infection on testis and sperm is a priority for reproductive biology, as well as for reproductive medicine. Here, we confirmed that the SARS-CoV-2 receptor angiotensin-converting enzyme 2 (ACE2) is highly expressed on human testis and ejaculated sperm; moreover, we provide evidence for the expression of the
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Rozprawy doktorskie na temat "Basigin receptor"

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Brown, Josephine Michelle. "Characterization of the interaction between Basigin and the pattern recognition receptor TLR4." UNF Digital Commons, 2016. http://digitalcommons.unf.edu/etd/650.

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Toll-like receptors (TLRs) are a major group of pattern recognition receptors expressed on the surface of immune cells that recognize molecular patterns associated with all classes of pathogenic microorganisms. TLR4 recognizes the lipopolysaccharide component of Gram-negative bacterial cell walls and is the only TLR known to induce signaling through both the MyD88 and TRIF pathways. Basigin, a ubiquitous cell adhesion molecule, is a member of the immunoglobulin superfamily that has the ability to influence cell signaling mediated by the MyD88 and TRIF pathways, the same signaling pathways indu
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Książki na temat "Basigin receptor"

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Calvillo, Jonathan E. In the Time of Sky-Rhyming. Oxford University PressNew York, 2024. http://dx.doi.org/10.1093/oso/9780197762479.001.0001.

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Abstract In the Time of Sky-Rhyming: How Hip Hop Resonated in Brown Los Angeles tracks the reception of Hip Hop by Latines in Los Angeles, when it first arrived there. The era when Hip Hop was first transposed onto the West Coast context, what this book calls the “time of sky-rhyming,” was an important step in Hip Hop’s global expansion, and Brown Los Angeles participated in its adaptation. Many creatives from Brown Los Angeles found their place in early underground expressions of Hip Hop, including in breaking, rhyming, DJing, and graffiti elements. The movement resonated in Brown Los Angeles
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Części książek na temat "Basigin receptor"

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Williams, J. B. "Real-time monitoring of the changing environment of the Aral Sea region: the role for low-cost, local reception of satellite data." In The Aral Sea Basin. Springer Berlin Heidelberg, 1996. http://dx.doi.org/10.1007/978-3-642-61182-7_17.

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Simonutti, Luisa. "Elsewhere. Women Translators and Travellers in Europe and the Mediterranean Basin in the Age of Enlightenment." In Gender and Cultural Mediation in the Long Eighteenth Century. Springer International Publishing, 2024. http://dx.doi.org/10.1007/978-3-031-46939-8_8.

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AbstractTravel as sentimental education, travel as cultural transfer and translation of texts, ideas, and emotions. Travel literature is an amalgam and hybridisation that can be analysed from different disciplinary perspective. Between the seventeenth and eighteenth centuries, this area became a sphere of expression not only for women philosophers, scientists and religious figures, but also for translators. Translation was mostly considered a non- creative activity, subordinate to the primacy of the author and hence devoid of the risk that the translator could independently promote ideas or fo
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Errington, Elizabeth. "Reconstructing Jamālgarhī and Appendix B: the archaeological record 1848-1923." In The Rediscovery and Reception of Gandhāran Art. Archaeopress Archaeology, 2022. http://dx.doi.org/10.32028/9781803272337-2.

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Information on the ancient remains of Gandhāra started being collected in the 1830s, notably by Claude-Auguste Court, a French officer of the Sikh ruler Ranjit Singh. Like many Europeans, he was initially searching for sites associated with Alexander the Great (Court 1836: 394; 1839; Mairs 2018: 584-585), but in the process produced what was deemed by Alexander Cunningham (Figure 1) the only accurate map of the Peshawar basin (Cunningham 1848: 130). Armed with this map, Cunningham – on his own quest for Alexander – discovered Jamālgarhī in early January 1848.
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Perkins, Daniel, Simon G. D. Ruffell, and Jerome Sarris. "Ayahuasca." In Psychedelics as Psychiatric Medications. Oxford University PressOxford, 2023. http://dx.doi.org/10.1093/med/9780192863607.003.0006.

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Abstract Ayahuasca is a psychedelic plant brew originating in the Amazon basin. It is typically made from two basic components: the ayahuasca vine (Banisteriopsis caapi), containing various harmala alkaloids, and the leaves of a plant containing the potent psychedelic dimethyltryptamine (DMT), such as the chacruna plant (Psychotria viridis). Evidence suggests the brew has been used for at least hundreds of years, primarily by indigenous tribes for a range of purposes including psychological and physical healing. The components of the brew exert a range of neurochemical effects, with recent res
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Behrendt, Kurt A. "Gandhāran imagery as remembered by Buddhist communities across Asia." In The Rediscovery and Reception of Gandhāran Art. Archaeopress Archaeology, 2022. http://dx.doi.org/10.32028/9781803272337-5.

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Gandhāran art endured and shaped Buddhist visual culture long after the great monasteries in the Peshawar Basin had fallen into ruin. Naturally, this impact is especially pronounced between the first and early sixth centuries when these Gandhāran institutions were active and connected through trade to Afghanistan (Bactria), Central Asia, and China. Artworks created for monastic complexes in the small regional centre of Gandhāra had an outsized impact on the Buddhist world because of their perceived legitimacy. Narrative formats from this region were also embraced as they effectively crossed cu
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Dunn, Nancy, and Fernando Saavedra. "Is there a moon in the United States? Information reception, flow and use in rural villages on the Amazon river basin of Peru." In Global Information Inequalities. Elsevier, 2008. http://dx.doi.org/10.1016/b978-1-84334-361-5.50005-5.

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Streszczenia konferencji na temat "Basigin receptor"

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Richter, Donald, Brain Lamb, Hal Westburg, Joseph Vaughan, and Mark Gross. "Development of Simple Dispersion Model for Simulation of Air Toxics in Urban Areas." In ASME 2004 Heat Transfer/Fluids Engineering Summer Conference. ASMEDC, 2004. http://dx.doi.org/10.1115/ht-fed2004-56371.

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The paper details the development of an air dispersion model, Simflx7, a computer model that requires a minimum amount of input data while still allowing for the use of both a ground reflection and a reflection from a confining layer above. Simflx7 is based on the classical Gaussian approach and can accommodate gridded independently varying emission sources and calculates the result of all sources emissions on multiple receptors. The project used “real world” data from the Seattle-Tacoma basin for the model demonstration and validation. A gridded inventory for an area of approximately 154 mile
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Jaya, Makky Sandra, Abdrahman Sharif, Ali Ahmed Reda Abdulkarim, Ghazali Ahmad Riza, Maleki Ali Hajian, and Elsebakhi Emad. "Accurate Pseudo Log Prediction Using Machine Learning Based Automatic Log Regularization and Feature Augmentation Method." In Abu Dhabi International Petroleum Exhibition & Conference. SPE, 2021. http://dx.doi.org/10.2118/207230-ms.

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Abstract Objectives/Scope: The performance of ML-based rock properties prediction from seismic with limited and sparse well data is very often inadequate. To address this limitation, we propose a novel automatic well log regularization (ALR) method with specially designed feature augmentation strategy to improve the prediction accuracy. The effectiveness of ALR method is showcased on field data in Malay basin where we successfully predict elastic logs with 30% higher accuracy, while using only 28% less training dataset. Methods, Procedures, Process: The ALR workflow (Figure 1): (1) feature sel
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