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1

Ouma, Stephen, Richard Kagia, and Faith Kamakia. "Determination of pharmacological activity of bioactives in Allium sativum using computational analysis." F1000Research 12 (February 9, 2023): 151. http://dx.doi.org/10.12688/f1000research.130105.1.

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Introduction: Use of natural products for management of diseases has increased widely due to the belief that natural products are less toxic than conventional medicines. Natural products have been utilised for management of chronic diseases such as diabetes and cancers. Respiratory infections have also been managed using natural products. Allium sativum is one of the natural products that has been utilised in the management of SARS-CoV infections, diabetes and cancer. Methods: This study was aimed at screening bioactive agents in Allium sativum using computational analysis. The targets of the
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Postružnik, Vesna, Slađana Stajčić, Dragana Borjan, et al. "Impact of Storage Conditions on Stability of Bioactive Compounds and Bioactivity of Beetroot Extract and Encapsulates." Processes 12, no. 7 (2024): 1345. http://dx.doi.org/10.3390/pr12071345.

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(1) Background: In this study, bioactive compounds (phenolics and betalains) extracted from beetroot were stabilized by encapsulation with maltodextrin and soy protein by the freeze drying method. Stability of bioactive compounds and bioactivities in a beetroot extract and encapsulates during 60 days of storage at 4 °C (without light) and at 25 °C (with and without light) were investigated. (2) Methods: Contents of bioactive compounds and bioactivity (antioxidant activity by DPPH, RP, and ABTS tests; anti-inflammatory and antihyperglycemic activity) were determined. Improvement in stability of
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Yates, Allison A., Johanna T. Dwyer, John W. Erdman, et al. "Perspective: Framework for Developing Recommended Intakes of Bioactive Dietary Substances." Advances in Nutrition 12, no. 4 (2021): 1087–99. http://dx.doi.org/10.1093/advances/nmab044.

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ABSTRACT Dietary bioactives are food substances that promote health but are not essential to prevent typical deficiency conditions. Examples include lutein and zeaxanthin, omega-3 fatty acids, and flavonoids. When quality evidence is available, quantified intake recommendations linking dietary bioactives with specific health benefits will enable health professionals to provide evidence-based information to consumers. Without evidence-based recommendations, consumers use information from available sources that often lack standards and rigor. This article describes a framework to develop guidanc
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Evans, Levi W., Samantha S. Romanick, and Bradley S. Ferguson. "Natural product inhibitors of acetyl-lysine erasers in the prevention and treatment of heart failure." Functional Foods in Health and Disease 7, no. 8 (2017): 577. http://dx.doi.org/10.31989/ffhd.v7i8.376.

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Background: Heart failure (HF) is a major public health concern, with five-year mortality rates following first admission for HF being approximately 50%, thereby stressing the need for novel therapeutic approaches. Histone deacetylases (HDACs) govern lysine acetylation of histone tails that regulates nucleosmal DNA. HDAC inhibitors have emerged as efficacious therapies in pre-clinical models of HF. Interest in diet-gene interactions has given rise to the study of ‘food bioactives’ as epigenetic regulators of gene expression that control human health and disease. These reports demonstrate that
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Ramadan, Mohamed Fawzy, Alessandra Durazzo, and Massimo Lucarini. "Advances in Research on Food Bioactive Molecules and Health." Molecules 26, no. 24 (2021): 7678. http://dx.doi.org/10.3390/molecules26247678.

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Fresh and processed food products are rich in bioactive molecules, including polysaccharides, vitamins, carotenoids, peptides, antioxidants, phenolics, phytosterols, and novel lipids. Bioactive molecules in food could prevent several diseases (i.e., metabolic syndrome, cardiovascular diseases, cancer, etc.). Thus, consumer awareness is growing about the health-promoting impact of food bioactive molecules. Health claims are essential added-value features, wherein health-enhancing potential of bioactives depend on their chemical structure. On the other hand, the investigation of the structure-fu
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Bordoni, A., C. Boesch, C. Malpuech-Brugère, C. Orfila, and L. Tomás-Cobos. "The role of bioactives in energy metabolism and metabolic syndrome." Proceedings of the Nutrition Society 78, no. 3 (2019): 340–50. http://dx.doi.org/10.1017/s0029665119000545.

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Some food bioactives potentially exert anti-obesity effects. Anthocyanins (ACN), catechins, β-glucan (BG) and n-3 long chain PUFA (LCPUFA) are among the most promising candidates and have been considered as a strategy for the development of functional foods counteracting body weight gain. At present, clinical trials, reviews and meta-analyses addressing anti-obesity effects of various bioactives or bioactive-rich foods show contradictory results. Abdominal obesity is an important criterion for metabolic syndrome (MetS) diagnosis along with glucose intolerance, dyslipidaemia and hypertension. F
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Cecchi, Nicola, Roberta Romanelli, Flavia Ricevuti, et al. "Bioactives in Oral Nutritional Supplementation: A Pediatric Point of View." Nutrients 16, no. 13 (2024): 2067. http://dx.doi.org/10.3390/nu16132067.

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Background: Oral nutritional supplements (ONSs) are crucial for supporting the nutritional needs of pediatric populations, particularly those with medical conditions or dietary deficiencies. Bioactive compounds within ONSs play a pivotal role in enhancing health outcomes by exerting various physiological effects beyond basic nutrition. However, the comprehensive understanding of these bioactives in pediatric ONSs remains elusive. Objective: This systematic narrative review aims to critically evaluate the existing literature concerning bioactive compounds present in oral nutritional supplements
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Günal-Köroğlu, Deniz, Aysenur Betul Bilgin, Gulsah Karabulut, Beyza Saricaoglu, and Esra Capanoglu. "Encapsulation of hydrophobic compounds in yeast cells: methods, characterization, and applications." Exploration of Foods and Foodomics 2, no. 3 (2024): 252–74. http://dx.doi.org/10.37349/eff.2024.00037.

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Encapsulation is a pivotal technique for protecting and enhancing the efficiency of sensitive natural bioactive substances, notably essential oils, vitamins, and phenolic compounds, widely used in foods and nutraceuticals. Critical considerations in selecting encapsulation agents encompass safety, release kinetics, stability, and cost-effectiveness. Yeast cells emerge as versatile carriers distinguished by their low cost, compatibility with biological systems, and eco-friendly degradation properties, accommodating both hydrophilic and hydrophobic bioactive agents. Various yeast strains, includ
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9

K B S, Sushma. "Bioactive Glass: A Review." International Journal of Science and Research (IJSR) 12, no. 6 (2023): 1645–49. http://dx.doi.org/10.21275/sr23612165802.

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Donsì, Francesco, and Giovanna Ferrari. "Changing the Vision in Smart Food Design Utilizing the Next Generation of Nanometric Delivery Systems for Bioactive Compounds." Foods 9, no. 8 (2020): 1100. http://dx.doi.org/10.3390/foods9081100.

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In modern foods, the delivery systems for bioactive compounds play a fundamental role in health promotion, wellbeing, and disease prevention through diet. Nanotechnology has secured a fundamental role in the fabrication of delivery systems with the capability of modulating the in-product and in-body behavior for augmenting bioavailability and activity of bioactive compounds. Structured nanoemulsions and nanoparticles, liposomes, and niosomes can be designed to improve bioactives preservation after ingestion, mucoadhesion, as well as of their release and pathophysiological relevance. In the fut
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Ghini, Veronica, Leonardo Tenori, Francesco Capozzi та ін. "DHA-Induced Perturbation of Human Serum Metabolome. Role of the Food Matrix and Co-Administration of Oat β-glucan and Anthocyanins". Nutrients 12, № 1 (2019): 86. http://dx.doi.org/10.3390/nu12010086.

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Docosahexaenoic acid (DHA) has been reported to have a positive impact on many diet-related disease risks, including metabolic syndrome. Although many DHA-enriched foods have been marketed, the impact of different food matrices on the effect of DHA is unknown. As well, the possibility to enhance DHA effectiveness through the co-administration of other bioactives has seldom been considered. We evaluated DHA effects on the serum metabolome administered to volunteers at risk of metabolic syndrome as an ingredient of three different foods. Foods were enriched with DHA alone or in combination with
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12

Sharma, Manoj B., Hend A. M. Abdelmohsen, Özlem Kap, et al. "Poly(2-Hydroxyethyl Methacrylate) Hydrogel-Based Microneedles for Bioactive Release." Bioengineering 11, no. 7 (2024): 649. http://dx.doi.org/10.3390/bioengineering11070649.

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Microneedle arrays are minimally invasive devices that have been extensively investigated for the transdermal/intradermal delivery of drugs/bioactives. Here, we demonstrate the release of bioactive molecules (estradiol, melatonin and meropenem) from poly(2-hydroxyethyl methacrylate), pHEMA, hydrogel-based microneedle patches in vitro. The pHEMA hydrogel microneedles had mechanical properties that were sufficiently robust to penetrate soft tissues (exemplified here by phantom tissues). The bioactive release from the pHEMA hydrogel-based microneedles was fitted to various models (e.g., zero orde
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13

D, S. BHAKUNI. "Bioactive Marine Alkaloids." Journal of Indian Chemical Society Vol. 71, June-Aug 1994 (1994): 329–40. https://doi.org/10.5281/zenodo.5895354.

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Central Drug Research Institute, Lucknow-226 001 <em>Manuscript received 29 September 1993</em> The chemistry and biology of bioactive marine alkaloids isolated during the last ten years have been reviewed. Syntheses of bioactive marine indole alkaloids, aplysinopins, bromoaplysinopsins, their relative and their biological activities are reported.
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14

Kussmann, Martin, and David Henrique Abe Cunha. "Nature has the answers: Discovering and validating natural bioactives for human health." Bioactive Compounds in Health and Disease 5, no. 10 (2022): 222. http://dx.doi.org/10.31989/bchd.v5i10.1000.

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Nature has the answer to many of our questions about human health. Natural bioactives, especially when derived from sustainable plant and food sources, provide a plethora of molecular solutions to nutritionally actionable, chronic conditions. The spectrum of these conditions, such as metabolic, immune, and gastrointestinal disorders, has changed with prolonged human life span, which should be matched with an appropriately extended health span: “adding years to life and adding life to years”. Natural bioactives can be classified into micronutrients (i.e., vitamins, and minerals), phytonutrients
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Rohan, P. Bhosale. "Airlift Reactor Design for the Production of Antiviral Bioactives." Airlift Reactor Design for the Production of Antiviral Bioactives 8, no. 10 (2023): 2. https://doi.org/10.5281/zenodo.10016186.

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Plant-based bioactive molecules such as polyphenols, curcumin, sesquiterpenes, triterpenes, flavonoids, and carotenoids were reported to offer immunity against coronavirus. Increasing population can pressure agricultural land to grow more of these plants. Hence, it's important to look at alternative sources. Fruit peels also contain these bioactive molecules but are usually thrown as waste as the production of bioactive from fruit peels is not economical owing to the high cost of extraction. In this study, an inexpensive airlift bioreactor was designed which can help reduce the price of extrac
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Jin, Juri, Md Helal Uddin Chowdhury, Md Hafizur Rahman, Ki-Young Choi, and Md Adnan. "Bioactive Compounds and Signaling Pathways of Wolfiporia extensa in Suppressing Inflammatory Response by Network Pharmacology." Life 13, no. 4 (2023): 893. http://dx.doi.org/10.3390/life13040893.

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Wolfiporia extensa (WE) is a medicinal mushroom and an excellent source of naturally occurring anti-inflammatory substances. However, the particular bioactive compound(s) and mechanism(s) of action against inflammation have yet to be determined. Here, we studied anti-inflammatory bioactive compounds and their molecular mechanisms through network pharmacology. Methanol (ME) extract of WE (MEWE) was used for GC-MS analysis to identify the bioactives, which were screened by following Lipinski’s rules. Public databases were used to extract selected bioactives and inflammation-related targets, and
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Cruz-Martins, Natália, Cristina Quispe, Celale Kırkın, et al. "Paving Plant-Food-Derived Bioactives as Effective Therapeutic Agents in Autism Spectrum Disorder." Oxidative Medicine and Cellular Longevity 2021 (August 21, 2021): 1–17. http://dx.doi.org/10.1155/2021/1131280.

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Autism spectrum disorder (ASD) is a neurodevelopmental disorder, where social and communication deficits and repetitive behaviors are present. Plant-derived bioactives have shown promising results in the treatment of autism. In this sense, this review is aimed at providing a careful view on the use of plant-derived bioactive molecules for the treatment of autism. Among the plethora of bioactives, curcumin, luteolin, and resveratrol have revealed excellent neuroprotective effects and can be effectively used in the treatment of neuropsychological disorders. However, the number of clinical trials
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Tamzi, Nafisa Nawar, Md Motiur Rahman, and Subhadeep Das. "Recent Advances in Marine-Derived Bioactives Towards Cancer Therapy." International Journal of Translational Medicine 4, no. 4 (2024): 740–81. https://doi.org/10.3390/ijtm4040051.

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The increase in cancer incidence in recent years necessitates urgent exploration of novel and alternative sources of natural bioactives for targeted cancer therapy. Approximately 75% of the Earth’s surface is covered by oceans, which are thought to harbor untapped physiologically active compounds with potential efficacy against cancer. Recently, a growing focus has been on isolating and investigating novel bioactive compounds derived from marine sources. Bioactive metabolites with diverse chemical structures, isolated from various marine species such as algae, mollusks, and actinomycetes, demo
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Badr, Ahmed Noah, Karolina Gromadzka, Mohamed Gamal Shehata, Kinga Stuper-Szablewska, Kinga Drzewiecka, and Adel Gabr Abdel-Razek. "Prospective antimycotoxigenic action of wild Opuntia ficus-indica by-products." Czech Journal of Food Sciences 38, No. 5 (2020): 308–14. http://dx.doi.org/10.17221/11/2020-cjfs.

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Numerous natural compounds perform pharmaceutical, antimycotic and antitoxic purposes in the body system. The aim was to evaluate new phytoconstituents that provide antimycotoxigenic properties against mycotoxins. Bioactive materials chosen were fruit peels and cladodes of wild Opuntia ficus-indica containing a measurable quantity of bioactive phytochemicals. The highest concentration of bioactive metabolites was recorded for protocatechuic and t-cinnamic acids. A reduction effect of bioactives was estimated against aflatoxins, ochratoxin A and zearalenone in a simulated body system. Antifunga
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Agrawal, Manas Yogendra, Shreyas Gaikwad, Sangeeta Srivastava, and Sanjay K. Srivastava. "Research Trend and Detailed Insights into the Molecular Mechanisms of Food Bioactive Compounds against Cancer: A Comprehensive Review with Special Emphasis on Probiotics." Cancers 14, no. 22 (2022): 5482. http://dx.doi.org/10.3390/cancers14225482.

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In an attempt to find a potential cure for cancer, scientists have been probing the efficacy of the food we eat and its bioactive components. Over the decades, there has been an exponentially increasing trend of research correlating food and cancer. This review explains the molecular mechanisms by which bioactive food components exhibit anticancer effects in several cancer models. These bioactive compounds are mainly plant based or microbiome based. While plants remain the primary source of these phytochemicals, little is known about probiotics, i.e., microbiome sources, and their relationship
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K.Shakila, K. Shakila, D. Sukumar D. Sukumar, R. Priya R. Priya, and R. Rajaselvi R.Rajaselvi. "Bioactive Polyphenols Of Bombax Ceiba." International Journal of Scientific Research 1, no. 1 (2012): 62–63. http://dx.doi.org/10.15373/22778179/jun2012/22.

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Bala, Saroj, Diksha Garg, Kandi Sridhar, et al. "Transformation of Agro-Waste into Value-Added Bioproducts and Bioactive Compounds: Micro/Nano Formulations and Application in the Agri-Food-Pharma Sector." Bioengineering 10, no. 2 (2023): 152. http://dx.doi.org/10.3390/bioengineering10020152.

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The agricultural sector generates a significant amount of waste, the majority of which is not productively used and is becoming a danger to both world health and the environment. Because of the promising relevance of agro-residues in the agri-food-pharma sectors, various bioproducts and novel biologically active molecules are produced through valorization techniques. Valorization of agro-wastes involves physical, chemical, and biological, including green, pretreatment methods. Bioactives and bioproducts development from agro-wastes has been widely researched in recent years. Nanocapsules are n
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Daliri, Eric, Deog Oh, and Byong Lee. "Bioactive Peptides." Foods 6, no. 5 (2017): 32. http://dx.doi.org/10.3390/foods6050032.

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IWAMORI, Masao. "Bioactive Glycosphingolipids." Journal of Japan Oil Chemists' Society 40, no. 5 (1991): 361–69. http://dx.doi.org/10.5650/jos1956.40.361.

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HENCH, LARRY L. "Bioactive Ceramics." Annals of the New York Academy of Sciences 523, no. 1 Bioceramics (1988): 54–71. http://dx.doi.org/10.1111/j.1749-6632.1988.tb38500.x.

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Wiederschain, G. Ya. "Bioactive Peptides." Biochemistry (Moscow) 75, no. 5 (2010): 671. http://dx.doi.org/10.1134/s0006297910050214.

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Xiao, Jianbo, and Weibin Bai. "Bioactive phytochemicals." Critical Reviews in Food Science and Nutrition 59, no. 6 (2019): 827–29. http://dx.doi.org/10.1080/10408398.2019.1601848.

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Shahidi, Fereidoon, and Ying Zhong. "Bioactive Peptides." Journal of AOAC INTERNATIONAL 91, no. 4 (2008): 914–31. http://dx.doi.org/10.1093/jaoac/91.4.914.

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Abstract Peptides with biological activities, released during gastrointestinal digestion or food processing, play an important role in metabolic regulation and modulation, suggesting their potential use as nutraceuticals and functional food ingredients for health promotion and disease risk reduction. Many studies have reported that peptides from various food sources possess bioactivities, including antihypertensive, antioxidant, anticancer, antimicrobial, and opioid activities as well as immunomodulatory and cholesterol-lowering effects. More studies are being performed exploring the sources,
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Shibuya, Terry Y., Sanghun Kim, Kevin Nguyen, et al. "Bioactive Suture." Clinical Cancer Research 10, no. 20 (2004): 7088–99. http://dx.doi.org/10.1158/1078-0432.ccr-04-0052.

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HUBBELL, J. "Bioactive biomaterials." Current Opinion in Biotechnology 10, no. 2 (1999): 123–29. http://dx.doi.org/10.1016/s0958-1669(99)80021-4.

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Cao, Wanpeng, and Larry L. Hench. "Bioactive materials." Ceramics International 22, no. 6 (1996): 493–507. http://dx.doi.org/10.1016/0272-8842(95)00126-3.

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Beldie, Cameluta, Severian Dumitriu, Nicolae Aelenei, Marcel Popa, Marcel I. Popa, and Daniela Dumitriu. "Bioactive polymers." Biomaterials 10, no. 9 (1989): 622–24. http://dx.doi.org/10.1016/0142-9612(89)90117-8.

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Neligan, Peter C. "Bioactive Sutures." Plastic and Reconstructive Surgery 118, no. 7 (2006): 1645–47. http://dx.doi.org/10.1097/01.prs.0000248418.23513.1f.

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Hengerer, A., E. Prohaska, J. Decker, et al. "Bioactive Films." Materials Science Forum 287-288 (August 1998): 169–80. http://dx.doi.org/10.4028/www.scientific.net/msf.287-288.169.

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Ducheyne, P. "Bioactive ceramics." Journal of Bone and Joint Surgery. British volume 76-B, no. 6 (1994): 861–62. http://dx.doi.org/10.1302/0301-620x.76b6.7983107.

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Alsharairi, Naser A. "A Review with a Focus on Vaccinium-Berries-Derived Bioactive Compounds for the Treatment of Reproductive Cancers." Plants 13, no. 7 (2024): 1047. http://dx.doi.org/10.3390/plants13071047.

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Cancers of the reproductive organs, including prostate, bladder, ovarian, and cervical cancers, are considered the most common causes of death in both sexes worldwide. The genus Vaccinium L. (Ericaceae) comprises fleshy berry crop species, including cranberries, blueberries, lingonberries, bilberries, and bog bilberries, and are widely distributed in many countries. Flavonols, anthocyanins (ACNs), proanthocyanidins (PACs), and phenolic acids are the most bioactive compounds naturally found in Vaccinium berries and have been extensively used as anticancer agents. However, it remains uncertain w
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Jin, Yuanyuan, Ling Chen, Yufen Yu, Muhammad Hussain, and Hao Zhong. "Bioactive Components in Fruit Interact with Gut Microbes." Biology 12, no. 10 (2023): 1333. http://dx.doi.org/10.3390/biology12101333.

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Fruits contain many bioactive compounds, including polysaccharides, oligosaccharides, polyphenols, anthocyanins, and flavonoids. All of these bioactives in fruit have potentially beneficial effects on gut microbiota and host health. On the one hand, fruit rich in active ingredients can act as substrates to interact with microorganisms and produce metabolites to regulate the gut microbiota. On the other hand, gut microbes could promote health effects in the host by balancing dysbiosis of gut microbiota. We have extensively analyzed significant information on bioactive components in fruits based
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Moysidou, Anastasia Maria, Konstantina Cheimpeloglou, Spyridoula Ioanna Koutra, Marios Argyrios Finos, Anna Ofrydopoulou, and Alexandros Tsoupras. "A Comprehensive Review on the Antioxidant and Anti-Inflammatory Bioactives of Kiwi and Its By-Products for Functional Foods and Cosmetics with Health-Promoting Properties." Applied Sciences 14, no. 14 (2024): 5990. http://dx.doi.org/10.3390/app14145990.

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Kiwi’s increased popularity as a healthy fruit with several agro-food applications has increased the amount of bio-waste produced like leaf, peel, and seed by-products, usually combined to form a kiwi pomace, which increases the environmental footprint of kiwi fruit and waste management costs. The aim of the present study is to thoroughly review and outline the nutritional content and bioactive components of both kiwi fruit and its by-products, as well as the innovative approaches to obtain and valorize kiwi’s bioactives, phytochemicals, vitamins, and nutrients in several functional food produ
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El-Ramady, Hassan, Peter Hajdú, Gréta Törős, et al. "Plant Nutrition for Human Health: A Pictorial Review on Plant Bioactive Compounds for Sustainable Agriculture." Sustainability 14, no. 14 (2022): 8329. http://dx.doi.org/10.3390/su14148329.

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Is there any relationship between plant nutrition and human health? The overall response to this question is very positive, and a strong relationship between the nutrition of plants and humans has been reported in the literature. The nutritional status of edible plants consumed by humans can have a negative or positive impact on human health. This review was designed to assess the importance of plant bioactive compounds for human health under the umbrella of sustainable agriculture. With respect to the first research question, it was found that plant bioactives (e.g., alkaloids, carotenoids, f
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Ismaiel, Lama, Valeria Rizzo, Carla Di Mattia, et al. "Oil-in-Water Emulsions Made of Pistachio Oil: Physical and Chemical Properties and Stability." Foods 14, no. 1 (2024): 60. https://doi.org/10.3390/foods14010060.

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Pistachio nuts are valued for their sensory qualities, nutritional benefits, and health-promoting properties. Pistachio oil has also gained interest for its bioactive compounds, though these are sensitive to processing and environmental stresses. While pistachio-based products are commercially available, little research has addressed the emulsifying properties of crude pistachio oil or its impact on the stability and bioactive profile of oil-in-water (O/W) emulsions. This study evaluated the emulsion-forming abilities of two commercial pistachio oils (PO1, PO2), their physical and oxidative st
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Sadiq, Uzma, Harsharn Gill, and Jayani Chandrapala. "Casein Micelles as an Emerging Delivery System for Bioactive Food Components." Foods 10, no. 8 (2021): 1965. http://dx.doi.org/10.3390/foods10081965.

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Bioactive food components have potential health benefits but are highly susceptible for degradation under adverse conditions such as light, pH, temperature and oxygen. Furthermore, they are known to have poor solubilities, low stabilities and low bioavailabilities in the gastrointestinal tract. Hence, technologies that can retain, protect and enable their targeted delivery are significant to the food industry. Amongst these, microencapsulation of bioactives has emerged as a promising technology. The present review evaluates the potential use of casein micelles (CMs) as a bioactive delivery sys
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Otvos, Reka A., Kristina B. M. Still, Govert W. Somsen, August B. Smit, and Jeroen Kool. "Drug Discovery on Natural Products: From Ion Channels to nAChRs, from Nature to Libraries, from Analytics to Assays." SLAS DISCOVERY: Advancing the Science of Drug Discovery 24, no. 3 (2019): 362–85. http://dx.doi.org/10.1177/2472555218822098.

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Natural extracts are complex mixtures that may be rich in useful bioactive compounds and therefore are attractive sources for new leads in drug discovery. This review describes drug discovery from natural products and in explaining this process puts the focus on ion-channel drug discovery. In particular, the identification of bioactives from natural products targeting nicotinic acetylcholine receptors (nAChRs) and serotonin type 3 receptors (5-HT3Rs) is discussed. The review is divided into three parts: “Targets,” “Sources,” and “Approaches.” The “Targets” part will discuss the importance of i
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Jacquier, Emma F., Marcel van de Wouw, Elena Nekrasov, Nikhat Contractor, Amira Kassis, and Diana Marcu. "Local and Systemic Effects of Bioactive Food Ingredients: Is There a Role for Functional Foods to Prime the Gut for Resilience?" Foods 13, no. 5 (2024): 739. http://dx.doi.org/10.3390/foods13050739.

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Scientific advancements in understanding the impact of bioactive components in foods on the gut microbiota and wider physiology create opportunities for designing targeted functional foods. The selection of bioactive ingredients with potential local or systemic effects holds promise for influencing overall well-being. An abundance of studies demonstrate that gut microbiota show compositional changes that correlate age and disease. However, navigating this field, especially for non-experts, remains challenging, given the abundance of bioactive ingredients with varying levels of scientific subst
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Sianipar, Herna Febrianty, Rezi Rahmi Amolia, Wahyu Widoretno, Luchman Hakim, and Fatchiyah Fatchiyah. "Bioactive Compounds Fruit Eaten Tapanuli Orangutans in Camp Mayang North Sumatera." BIO Web of Conferences 183 (2025): 01002. https://doi.org/10.1051/bioconf/202518301002.

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Bioactive compounds are important components that the Tapanuli orangutan (Pongo tapanuliensis) needs to maintain its health. It is important to know the specific bioactive components contained in the fruit that Tapanuli orangutans eat and the effective solvents to provide up-to-date information about the content of the fruit they eat. This research uses the maceration method with ethanol and methanol solvents to determine the solvent that produces larger extracts as well as liquid chromatography-mass spectrum to analyze the bioactive component profiles of five types of fruit eaten by Tapanuli
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Marra, Anita, Vasileios Manousakis, Georgios Panagiotis Zervas, et al. "Avocado and Its By-Products as Natural Sources of Valuable Anti-Inflammatory and Antioxidant Bioactives for Functional Foods and Cosmetics with Health-Promoting Properties." Applied Sciences 14, no. 14 (2024): 5978. http://dx.doi.org/10.3390/app14145978.

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Avocado (Persea americana) is a unique fruit with exceptional nutritional and technological characteristics, as well as proposed health benefits. Moreover, the commercial utilization of avocado to make guacamole and/or to extract its oil for several applications generates massive amounts of avocado bio-wastes, including peels and seeds by-products, which further impact the environment and waste management costs. Within this article, the proposed health benefits of moderate avocado consumption, as a functional component of a balanced diet against inflammation-related chronic disorders, and its
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Bellantone, M., and Larry L. Hench. "Bioactive Behaviour of Sol-Gel Derived Antibacterial Bioactive Glass." Key Engineering Materials 192-195 (September 2000): 617–20. http://dx.doi.org/10.4028/www.scientific.net/kem.192-195.617.

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Sarmiento-Tovar, Aixa A., Laura Silva, Jeysson Sánchez-Suárez, and Luis Diaz. "Streptomyces-Derived Bioactive Pigments: Ecofriendly Source of Bioactive Compounds." Coatings 12, no. 12 (2022): 1858. http://dx.doi.org/10.3390/coatings12121858.

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Pigments have been used since historical times and are currently used in food, cosmetic, pharmaceutical, and other industries. One of the main sources of natural pigments are plants and insects; however, microorganisms are of great interest due to their bioactivities and advantages in their production. Actinobacteria, especially the genus Streptomyces, are biotechnologically valuable, producing specialized metabolites with a broad spectrum of bioactivities, such as antioxidant, anticancer, antibiofilm, antifouling, and antibiotic activities, as well as pigments, among others. In this review, w
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Par, Matej, Zrinka Tarle, Reinhard Hickel, and Nicoleta Ilie. "Polymerization kinetics of experimental bioactive composites containing bioactive glass." Journal of Dentistry 76 (September 2018): 83–88. http://dx.doi.org/10.1016/j.jdent.2018.06.012.

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Cornelia, Melanie, Kam Natania, Herry Cahyana, and Edison Sutiyono. "Encapsulation of Soursop (Annona muricata Linn.) Leaf Tea Extract Using Natural Mucilage." Reaktor 19, no. 1 (2019): 26–33. http://dx.doi.org/10.14710/reaktor.19.1.26-33.

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The bioactively rich soursop leaf extract can be encapsulated inside several natural coating materials. The extract of soursop leaf has been found to contain many bioactive compounds such as various phenolic compounds that are beneficial for anticancer, antidiabetic and many other health benefits. However due to the sensitive nature of the bioactive molecules, encapsulation procedure was applied to prolong the activity of the biomolecules. Capsule materials used in this experiment were obtained from natural extract of Okra mucilage, Aloe vera mucilage and Maltodextrin-WPI mixture to protect th
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Tsoupras, Alexandros, Donal Moran, Thomas Byrne, et al. "Anti-Inflammatory and Anti-Platelet Properties of Lipid Bioactives from Apple Cider By-Products." Molecules 26, no. 10 (2021): 2869. http://dx.doi.org/10.3390/molecules26102869.

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The valorization of food industry by-products as sources of bioactive compounds is at the forefront of research in functional foods and nutraceuticals. This study focuses on bioactives of apple cider by-products (ACBPs) with putative cardio-protective properties. Total lipids (TLs) were extracted from ACBPs of apple varieties that are low (ACBP1), medium (ACBP2), and high (ACBP3) in tannins and were further separated into polar lipids (PLs) and neutral lipids (NLs). The functionality of these lipid extracts and of their HPLC-derived lipid fractions/PL subclasses were assessed in vitro against
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