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Rozprawy doktorskie na temat „Bone marrow”

Autor: Grafiati

Data publikacji: 4 czerwca 2021

Data aktualizacji: 25 lipca 2025

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1

勞錦輝 and Kam-fai Simon Lo. "Cytomegalovirus and bone marrow transplantation." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 1997. http://hub.hku.hk/bib/B31215609.

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Lo, Kam-fai Simon. "Cytomegalovirus and bone marrow transplantation /." Hong Kong : University of Hong Kong, 1997. http://sunzi.lib.hku.hk/hkuto/record.jsp?B19471142.

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Fadini, Gian Paolo. "Bone marrow dysfunction in diabetes." Doctoral thesis, Università degli studi di Padova, 2013. http://hdl.handle.net/11577/3422580.

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Background. Diabetes mellitus (DM) increases cardiovascular disease (CVD) and this is attributed, at least in part, to shortage of vascular regenerative cells derived from the bone marrow (BM). Indeed, the BM harbours several subsets of progenitor cells for endothelial, smooth muscle cells and cardiomyocytes, which derive from a common CD34+ ancestor. Recent data from experimental models of type 1 and type 2 diabetes highlight BM pathologies that include microangiopathy, neuropathy, altered gene expression and niche dysfunction. Aims. The set of experiments herein described aim to portray the

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4

Fisher, Maya. "Bone marrow regeneration follwing tibial marrow ablation in rats is age dependent." Thesis, Atlanta, Ga. : Georgia Institute of Technology, 2008. http://hdl.handle.net/1853/26526.

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Thesis (M. S.)--Biology, Georgia Institute of Technology, 2009.<br>Committee Chair: Boyan Barbara; Committee Member: Guldberg Robert; Committee Member: Lovachev Kiril; Committee Member: Schwartz Zvi. Part of the SMARTech Electronic Thesis and Dissertation Collection.

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5

Jackson, G. H. "Long term bone marrow culture studies of patients with lymphoid malignancies undergoing autologous bone marrow transplantation." Thesis, University of Newcastle Upon Tyne, 1991. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.309068.

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6

Schmidt-Mende, Jan Georg. "Bone marrow apoptosis in myelodysplastic syndromes." [S.l.] : [s.n.], 2003. http://deposit.ddb.de/cgi-bin/dokserv?idn=96939781X.

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7

McIntosh, Bryan James. "Regulation of thrombopoietin in bone marrow." Connect to a 24 p. preview or request complete full text in PDF format. Access restricted to UC campuses, 2007. http://wwwlib.umi.com/cr/ucsd/fullcit?p3284334.

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Thesis (Ph. D.)--University of California, San Diego, 2007.<br>Title from first page of PDF file (viewed January 9, 2008). Available via ProQuest Digital Dissertations. Vita. Includes bibliographical references (p. 50-58).

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8

Funaki, Hilde. "Psychological responses to bone-marrow-transplantation." Thesis, City University London, 1994. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.283269.

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9

Sebastian, Anil. "Recreating bone marrow tissues in vitro." Thesis, University of Manchester, 2008. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.528263.

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10

Davison, Glenda Mary. "Immune reconstitution post bone marrow transplantation." Master's thesis, University of Cape Town, 2000. http://hdl.handle.net/11427/3376.

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Bibliography: leaves 82-95.<br>The aims of this project were therefore: to document the immune reconstitution following T-cell depleted bone marrow and peripheral blood stem cell transplantation and to compare this with the recovery following autologous grafts. to document the cell surface expression of CD95 in an attempt to comment on the role played by FAS mediated apoptosis in the post transplant immune deficiency.

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11

Weber, Matthew Charles. "Engineering human bone marrow stromal cells." Case Western Reserve University School of Graduate Studies / OhioLINK, 1991. http://rave.ohiolink.edu/etdc/view?acc_num=case1055867071.

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12

Avera, Emily. "Transplant anxieties : discourses about bone marrow." Master's thesis, University of Cape Town, 2008. http://hdl.handle.net/11427/10038.

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Includes bibliographical references (leaves 89-94).<br>This minor dissertation examines the various discourses in the Bone Marrow Transplant (BMT) network in South Africa. The organisations in the network which were observed using participant observation were the South African Bone Marrow Registry and the Sunflower Fund to complement this, the researcher interviewed staff members at these organisations as well as at a public hospital haematology unit in the Cape Town area that conducts BMT. Additionally patients, donors, and their family members were interviewed. Some media related to the BMT

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13

Mancini, Richard Anthony. "Factors affecting beef bone marrow discoloration /." Search for this dissertation online, 2004. http://wwwlib.umi.com/cr/ksu/main.

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14

Hussein, Hayam. "Cathepsin K Inhibition In Bone And Bone Marrow In Horses." The Ohio State University, 2015. http://rave.ohiolink.edu/etdc/view?acc_num=osu1449218489.

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15

LACAVA, GIOVANNA. "A Comprehensive Study on Homeostatic Bone and Bone Marrow Mediators." Doctoral thesis, Università degli Studi di Camerino, 2019. http://hdl.handle.net/11581/428952.

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Bone marrow is an extremely complex tissue, whose function is to accommodate the hematopoietic and the bone stem/progenitor cells. In particular, the bone marrow stromal microenvironment consists of several different types of cells, including bone lining osteoblasts, endothelial cells, reticular adventitial cells, neuronal cells and mesenchymal stem cells. Here, this large number of different populations coexist and exchange several signals in order to preserve bone marrow homeostasis. Accordingly, it is necessary to highlight that changes in the bone marrow steady-state may lead to localized

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16

Clutter, Suzanne Davis. "Chemotherapy disrupts bone marrow stromal cell function." Morgantown, W. Va. : [West Virginia University Libraries], 2006. https://eidr.wvu.edu/etd/documentdata.eTD?documentid=4528.

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Thesis (Ph. D.)--West Virginia University, 2006.<br>Title from document title page. Document formatted into pages; contains x, 180 p. : ill. (some col.). Vita. Includes abstract. Includes bibliographical references.

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17

Baki, Mert. "Bone Marrow Targeted Liposomal Drug Delivery Systems." Master's thesis, METU, 2011. http://etd.lib.metu.edu.tr/upload/12613251/index.pdf.

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Homing is the process that stem cells move to their own stem cell niches under the influence of chemokines like stromal-derived factor-1&alpha<br>(SDF-1&alpha<br>) upon bone marrow transplantation (BMT). There is a need for increasing homing efficiency after BMT since only 10-15% of the transplanted cells can home to their own niches and a limited amount of donor marrow can be transplanted. In this study, we aimed to develop and characterize bone marrow targeted liposomal SDF-1&alpha<br>delivery system prepared by extrusion method. Alendronate conjugation was chosen to target the liposomes to

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18

Fletcher, Joanne L. "Bone Marrow Progenitors in Vascular Tissue Engineering." Thesis, University of Manchester, 2009. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.518451.

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19

Bågesund, Mats. "Salivary function after pediatric bone marrow transplantation /." Stockholm, 2000. http://diss.kib.ki.se/2000/91-628-4110-6/.

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20

Amofah, Eunice. "Bone marrow stem cells in liver disease." Thesis, Imperial College London, 2007. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.497234.

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21

袁國勇 and Kwok-yung Yuen. "Infectious complications in bone marrow transplant recipients." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 1998. http://hub.hku.hk/bib/B31981689.

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22

Chandran, Priya. "Bone Marrow Microenvironment in Acute Myleoid Leukemia." Thèse, Université d'Ottawa / University of Ottawa, 2013. http://hdl.handle.net/10393/24301.

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Acute myeloid leukemia (AML) often remains refractory to current chemotherapy and transplantation approaches despite many advances in our understanding of mechanisms in leukemogenesis. The bone marrow “niche” or microenvironment, however, may be permissive to leukemia development and studying interactions between the microenvironment and leukemia cells may provide new insight for therapeutic advances. Mesenchymal stem cells (MSCs) are central to the development and maintenance of the bone marrow niche and have been shown to have important functional alterations derived from patients with diffe

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23

McWilliam, Nicola A. "The fibrinolytic system of human bone marrow." Thesis, University of Aberdeen, 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.337476.

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The fibrinolytic system of normal and leukaemic bone marrow was examined. Normal bone marrow had a very active fibrinolytic system due to abundant free t-PA, with negligible contribution from u-PA. High levels of PAI-2 antigen were observed in addition to PAI-1. Plasminogen, the precursor of plasmin was detected, mainly in complex with α<sub>2</sub>-AP, indicating that plasmin had been generated. The balance of the fibrinolytic system in normal bone marrow contrasted with the system in plasma, where plasmin is not normally generated. In bone marrow the t-PA level was greater than that of the i

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24

Elfer, Jane. "Emotional impact of sibling bone marrow donors." Thesis, University of East London, 2017. http://roar.uel.ac.uk/7137/.

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This thesis reports on a study of the emotional impact on sibling bone marrow donors. lt considers in particular donation that takes place during their adolescence and was prompted by the concern of medical and nursing colleagues managing the treatment of young people with cancer. The study interviewed five donors and discusses these interviews using the lens of psychoanalytic theory to offer a deeper understanding of these donors' experiences. Understood in this way, particularly using the psychoanalytic concept of projective identification, a main finding of the study is that whilst these do

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25

Rehman, Haroon, Asha Chepkorir Segie, Kanishka Chakraborty, and Devapiran Jaishankar. "Bone Marrow Wars: Attack of the Clones." Digital Commons @ East Tennessee State University, 2020. https://dc.etsu.edu/asrf/2020/presentations/33.

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Multiple myeloma is characterized by the malignant proliferation of clonal plasma cells producing monoclonal paraproteins, leading to multi-organ damage. On the other hand monoclonal B-cell lymphocytosis (MBCL) is characterized by the malignant proliferation of clonal B-lymphocytes, with potential to develop into chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL). CLL/SLL can result in visceromegaly, anemia, thrombocytopenia, fevers, night sweats and unintentional weight loss. Literature review demonstrates these two malignant clonal bone marrow disorders are most frequentl

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26

Yuen, Kwok-yung. "Infectious complications in bone marrow transplant recipients." Hong Kong : University of Hong Kong, 1998. http://sunzi.lib.hku.hk/hkuto/record.jsp?B19929614.

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27

Lloyd, Brandon R. "Comparison of Bone Marrow Mesenchymal Stem Cells from Limb and Jaw Bones." The Ohio State University, 2016. http://rave.ohiolink.edu/etdc/view?acc_num=osu1458678153.

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28

Hall, Brett Matthew. "Effects of high dose chemotherapy on the bone marrow microenvironment." Morgantown, W. Va. : [West Virginia University Libraries], 2002. http://etd.wvu.edu/templates/showETD.cfm?recnum=2558.

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Thesis (Ph. D.)--West Virginia University, 2002.<br>Title from document title page. Document formatted into pages; contains ix, 173 p. : ill. (some col.). Vita. Includes abstract. Includes bibliographical references (p. 163-169).

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29

Lu, King-hei Crosby. "A single centre, randomised trial on harvest cell yield and marrow engraftment using haemopoietic growth-factor primed bone marrow." Hong Kong : University of Hong Kong, 2002. http://sunzi.lib.hku.hk/hkuto/record.jsp?B25176481.

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30

Bailey, Amy. "A systemic approach to paediatric bone marrow transplantation." Thesis, University of Birmingham, 2004. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.408830.

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31

Gray, Caroline J. "Distress and emotional state throughout bone marrow transplantation." Thesis, University of British Columbia, 1991. http://hdl.handle.net/2429/29729.

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Bone marrow Transplantation causes a variety of symptoms and emotional states which change throughout the treatment. The purpose of this descriptive correlational, repeated measures study was to describe the type and degree of symptom distress and the emotional states experienced by BMT patients at the time of admission, through the administration of chemotherapy and radiotherapy, bone marrow infusion, waiting for engraftment to 25 days following the infusion of bone marrow. In addition, this study investigated the relationship between symptom distress and emotional states of the BMT patient.

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32

Barron, Mary Anne. "Vitamin K deficiency in paediatric bone marrow transplantation." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1998. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape11/PQDD_0008/MQ40822.pdf.

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33

Rodriguez, Francisco Jose. "Oral mucositis in children receiving bone marrow transplantation." Thesis, Birmingham, Ala. : University of Alabama at Birmingham, 2008. https://www.mhsl.uab.edu/dt/2008m/rodriguez.pdf.

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34

Al-Khaldi, Abdulaziz A. "Therapeutic angiogenesis using autologous bone marrow stromal cells." Thesis, McGill University, 2002. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=32749.

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Objectives. To study marrow stromal cells (MSCs) induced angiogenesis. To examine the possible mechanisms involved in the process. To evaluate neovascularization following implantation of MSCs in ischemic hind limb model.<br>Methods and result. Using murine Matrigel angiogenesis model, we compared MSCs related angiogenesis to that produced by vascular endothelial growth factor (VEGF) and basic fibroblast growth factor. We found that MSCs result in an efficient and organized angiogenesis, arteriogenesis and vasculogenesis. MSC-related angiogenesis is VEGF dependent. MSCs in vivo produce VEGF th

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35

Vig, Pamela. "Bone marrow stem cell contribution to liver regeneration." Thesis, Imperial College London, 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.427949.

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36

Burdon, Peter Charles Edward. "Regulation of neutrophil mobilisation from the bone marrow." Thesis, Imperial College London, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.289739.

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37

Powell, Timothy Jack. "Characterisation of rat bone marrow derived dendritic cells." Thesis, University of Oxford, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.298613.

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38

Kallis, Yiannis Nicolaou. "The bone marrow in liver fibrosis and regeneration." Thesis, Imperial College London, 2010. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.528283.

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39

Porter, Christopher John Hamilton. "Targeting collodial drug carriers to the bone marrow." Thesis, University of Nottingham, 1992. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.315061.

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40

Cavanagh, Gary. "The role of CD31 in bone marrow transplantation." Thesis, University of Newcastle Upon Tyne, 2004. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.404955.

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Fegan, C. D. "The gut mucosal barrier following bone marrow transplantation." Thesis, University of Newcastle Upon Tyne, 1992. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.308776.

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42

Wadoodi, Ashar. "The role of bone marrow in thrombus resolution." Thesis, King's College London (University of London), 2012. https://kclpure.kcl.ac.uk/portal/en/theses/the-role-of-bone-marrow-in-thrombus-resolution(2983faec-0618-4c4f-8897-7816419c55bd).html.

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Deep vein thrombosis (DVT) is a common condition affecting 1-2% of the population. It can be further complicated by serious sequelae such as life threatening pulmonary embolus and the chronically debilitating post-thrombotic syndrome. The main treatment modalities available for DVT are only able to limit disease progression, with resolution occurring physiologically. Natural resolution of DVT occurs through a process of thrombus retraction and recanalisation which is comparable to progenitor mediated neovascularisation. The focus of this project was to examine the circulating progenitor cell r

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43

Davies, Julie Theresa. "Activation of adhesion of bone marrow stromal cells." Thesis, St George's, University of London, 2014. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.656858.

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Osteoblasts, the bone-forming cells, derive from multipotential bone marrow stromal precursors called colony-forming units-fibroblastic (CFU-F). CFU-F rapidly adhere to plastic upon culture ex vivo, adhesion of such stromal precursors to bone in vivo is likely to be an early event in the anabolic response to bone stimulatory factors. It has been suggested that osteoclasts are involved in the activation of bone formation during bone remodelling. In order to test this, osteoclast conditioned medium was prepared from osteoclasts cultured on either plastic or bone. It was then used as culture medi

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44

Bennett, Jonathan Hilary. "The differentiation of osteogenic cells from bone marrow." Thesis, University of Oxford, 1991. http://ora.ox.ac.uk/objects/uuid:3460f26e-a124-4605-8601-2e300241de14.

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Roulson, Jo-An. "Bone marrow endothelial transmigration of prostate carcinoma cells." Thesis, University of Manchester, 2008. https://www.research.manchester.ac.uk/portal/en/theses/bone-marrow-endothelial-transmigration-of-prostate-carcinoma-cells(997acbf2-bbbc-455b-bb84-b439ffb9f839).html.

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46

Lyndina, Yu. "Histological features of red bone marrow in rats." Thesis, Sumy State University, 2016. http://essuir.sumdu.edu.ua/handle/123456789/46296.

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Bone marrow is the flexible tissue in the interior of bones. In humans, red blood cells are produced by cores of bone marrow in the heads of long bones in a process known as hematopoiesis. The hematopoietic component of bone marrow produces approximately 500 billion blood cells per day, which use the bone marrow vasculature as a conduit to the body's systemic circulation. Bone marrow is also a key component of the lymphatic system, producing the lymphocytes that support the body's immune system. Information about the normal structure of the bone marrow is a key step in understanding its change

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47

Gowers, Kate Hayley Christine. "Characterisation of bone marrow progenitor cells in disease." Thesis, Imperial College London, 2013. http://hdl.handle.net/10044/1/11068.

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The bone marrow serves as a reservoir for leukocytes and stem cells, from where cells can be mobilised into the circulation and can be recruited to sites of inflammation. Mobilisation of cells out of the bone marrow is dependent on their migration across the bone marrow sinusoidal endothelium, which is thought to be structurally and functionally different to endothelial cells from other vascular beds. In order to characterise the bone marrow endothelium and to study the molecular mechanisms involved in the mobilisation of cells, a protocol to isolate bone marrow endothelial cells and to grow t

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48

Langford-Smith, Kia Jane. "Non-myeloablative bone marrow transplantation for Mucopolysaccharide diseases." Thesis, University of Manchester, 2012. https://www.research.manchester.ac.uk/portal/en/theses/nonmyeloablative-bone-marrow-transplantation-for-mucopolysaccharide-diseases(5d3fd9c5-01f2-42aa-81ed-a2ce6ef140fe).html.

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The Mucopolysaccharide (MPS) diseases are a group of lysosomal storage disorders, caused by a lack of the enzymes required for catabolism of glycosaminoglycans (GAGs), leading to severe neurological decline, skeletal deformities, organomegaly, cardiac and respiratory compromise, and premature death. The severe form of MPS I, Hurler syndrome, can be successfully treated using haematopoietic stem cell transplantation (HSCT), but the risks associated with myeloablation and immune suppression limit the broader application of HSCT to attenuated diseases. Successful engraftment in MPS I has been dif

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Tandy, Corinne B. "Time line of decomposition of porcine bone marrow." Thesis, Boston University, 2011. https://hdl.handle.net/2144/38104.

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Thesis (M.S.)--Boston University<br>PLEASE NOTE: Boston University Libraries did not receive an Authorization To Manage form for this thesis or dissertation. It is therefore not openly accessible, though it may be available by request. If you are the author or principal advisor of this work and would like to request open access for it, please contact us at open-help@bu.edu. Thank you.<br>The postmortem interval, or time since death, is a significant factor in medicolegal death investigations. Currently, the techniques used to assess time since death are subjective, phase-based qualitative meth

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50

Porter, Ryan Michael. "Examination of Glucocorticoid Treatment on Bone Marrow Stroma: Implications for Bone Disease and Applied Bone Regeneration." Thesis, Virginia Tech, 2002. http://hdl.handle.net/10919/36365.

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Long-term exposure to pharmacological doses of glucocorticoids has been associated with the development of osteopenia and avascular necrosis. Bone loss may be partially attributed to a steroid-induced decrease in the osteoblastic differentiation of multipotent progenitor cells found in the bone marrow. In order to determine if there is a change in the osteogenic potential of the bone marrow stroma following glucocorticoid treatment, Sprague-Dawley rats were administered methylprednisolone for up to six weeks, then sacrificed at 0, 2, 4, or 6 weeks during treatment or 4 weeks after cessation

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