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Artykuły w czasopismach na temat "CD8+ Treg cells"

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Panda, Abir Kumar, and Ethan M. Shevach. "CD28 co-stimulation drives memory phenotype (MP) Treg cell and MP CD4+Foxp3− effector T cell homeostatic proliferation." Journal of Immunology 200, no. 1_Supplement (2018): 112.11. http://dx.doi.org/10.4049/jimmunol.200.supp.112.11.

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Abstract Foxp3+Tregs, CD4+Foxp3− effector T cells and CD8+ T cells are composed of naïve (NP, CD44loCD62Lhi) and memory (MP, CD44hiCD62Llo) subsets. About 30% of MP T cells are cycling (Ki-67+) in-vivo. To determine the factors that drive T cell homeostatic proliferation in-vivo, we investigated the roles of cytokines (TNFa, IL-2, IL-7, and IL-33), TCR-MHC-II interactions, co-stimulatory (CD28, ICOS, CD40, GITR, OX40), and co-inhibitory (CTLA-4, PD1, BTLA, TIGIT) receptors. Blockade of CD28-CD80/86 signaling completely inhibited MP Treg and MP CD4+Foxp3− effector T cell proliferation but did n
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Ceeraz, Sabrina, Charlotte R. Thompson, Richard Beatson, and Ernest H. Choy. "Harnessing CD8+CD28− Regulatory T Cells as a Tool to Treat Autoimmune Disease." Cells 10, no. 11 (2021): 2973. http://dx.doi.org/10.3390/cells10112973.

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T regulatory cell therapy presents a novel therapeutic strategy for patients with autoimmune diseases or who are undergoing transplantation. At present, the CD4+ Treg population has been extensively characterized, as a result of defined phenotypic and functional readouts. In this review article, we discuss the development and biology of CD8+ Tregs and their role in murine and human disease indications. A subset of CD8+ Tregs that lack the surface expression of CD28 (CD8+CD28− Treg) has proved efficacious in preclinical models. CD8+CD28− Tregs are present in healthy individuals, but their impai
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Gardell, Jennifer L., Courtney Crane, Justin Bowser, et al. "Bispecific CD8 Treg modulators regulate a novel regulatory CD8 T cell network and eliminate pathogenic CD4 T cells in live cell co-culture system." Journal of Immunology 208, no. 1_Supplement (2022): 174.16. http://dx.doi.org/10.4049/jimmunol.208.supp.174.16.

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Abstract INTRODUCTION Others have described a subset of CD8 T cells (CD8 Treg) with immunosuppressive characteristics in inflammatory disease settings. CD8 Treg activation through canonical T cell receptors results in their oligoclonal expansion and perforin dependent elimination of pathogenic CD4 T cells. We have described the CD8 Treg network in Celiac patients and its potential to eliminate pathogenic CD4 T cells. Here we describe bispecific CD8 Treg modulators that activate CD8 Tregs, resulting in pathogenic CD4 T cell death. METHODS Novel bispecific CD8 Treg modulators were tested for tar
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Zhang, Zhu Xu, Ye Su, Xuyan Huang, Dameng Lian, and Anthony Jevnikar. "CD4+ but not CD8+ memory T cells escape DN Tregs-mediated regulation via expression of Serpin Protease Inhibitor 6 (P2160)." Journal of Immunology 190, no. 1_Supplement (2013): 69.18. http://dx.doi.org/10.4049/jimmunol.190.supp.69.18.

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Abstract Memory T cell (Tm) homeostasis is poorly understood and is a critical challenge to prevent transplant rejection. At present there are no effective clinical strategies to control Tm and contradictory reports exist as to their control by regulatory T cell (Treg). We previously found that TCRab+CD3+CD4-CD8-NK1.1- (double-negative, DN) Treg could effectively suppress CD4+ and CD8+ effector T cells and thus prevent transplant rejection. We utilized this model to test whether DN Tregs could similarly suppress Tm. Interestingly DN Tregs suppressed CD8+ Tm but had no effect on CD4+ Tm cells.
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Maurer, Meghan, Justin Bowser, Rachael Fasnacht, et al. "Demonstration of regulatory CD8 T cell prevalence, phenotype, and functions in autoimmune patients treated with a tolerizing peptide vaccine." Journal of Immunology 208, no. 1_Supplement (2022): 123.10. http://dx.doi.org/10.4049/jimmunol.208.supp.123.10.

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Abstract INTRODUCTION Others have described a subset of CD8 T cells with immunosuppressive characteristics in inflammatory disease settings. CD8 Treg activation, through a canonical T cell receptor, results in oligoclonal expansion and perforin dependent elimination of pathogenic CD4 T cells. We have demonstrated the CD8 Treg network in Celiac patients, and that CD8 Tregs can be modulated to enhance their cytolytic elimination of pathogenic CD4 T cells. Here, we evaluate culture conditions to enhance CD8 Treg functions, and describe the impact of a gluten tolerizing peptide vaccine on CD8 Treg
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Rushbrook, Simon M., Scott M. Ward, Esther Unitt, et al. "Regulatory T Cells Suppress In Vitro Proliferation of Virus-Specific CD8+ T Cells during Persistent Hepatitis C Virus Infection." Journal of Virology 79, no. 12 (2005): 7852–59. http://dx.doi.org/10.1128/jvi.79.12.7852-7859.2005.

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ABSTRACT The basis of chronic infection following exposure to hepatitis C virus (HCV) infection is unexplained. One factor may be the low frequency and immature phenotype of virus-specific CD8+ T cells. The role of CD4+CD25+ T regulatory (Treg) cells in priming and expanding virus-specific CD8+ T cells was investigated. Twenty HLA-A2-positive patients with persistent HCV infection and 46 healthy controls were studied. Virus-specific CD8+ T-cell proliferation and gamma interferon (IFN-γ) frequency were analyzed with/without depletion of Treg cells, using peptides derived from HCV, Epstein-Barr
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Botta, Gregory P., Tatiana Hurtado De Mendoza, Harri Jarvelainen, and Erkki Ruoslahti. "iRGD in combination with IL-2 reprograms tumor immunosuppression." Journal of Clinical Oncology 37, no. 8_suppl (2019): 55. http://dx.doi.org/10.1200/jco.2019.37.8_suppl.55.

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55 Background: Fibrotic solid tumors have lagged in immunotherapy efficacy. Although breast cancer (BC) shows modest single-agent activity, pancreatic ductal adenocarcinoma (PDAC) immunotherapy has repeatedly failed in clinical trials. A protective desmoplastic, inflammatory reaction encapsulates BC and PDAC where it can make up to 80% of the tumor microenvironment (TME). Reports in BC and PDAC patients and mouse models suggest that tumoricidal effector CD8+ T-cells are indeed present, yet suppressed by regulatory CD4+/CD25+/FoxP3+ T-cells (Tregs) and myeloid cells. Long-term PDAC and BC survi
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Gardell, Jennifer, Daniel Boster, Justin Bowser, et al. "A NOVEL BISPECIFIC CD8 TREG MODULATOR TARGETING CYTOLYTIC CD8 REGULATORY T CELLS REDUCES PATHOGENIC CD4 T CELLS AND INFLAMMATION IN TRANSLATIONAL MODELS OF INTESTINAL AUTOIMMUNE AND INFLAMMATORY DISEASE." Inflammatory Bowel Diseases 29, Supplement_1 (2023): S12. http://dx.doi.org/10.1093/ibd/izac247.024.

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Abstract INTRODUCTION We have characterized a novel CD8 Treg network in autoimmune patient peripheral blood and tissues, in which a subset of cytolytic CD8 Treg eliminate pathogenic CD4 T cells, reducing inflammation and ameliorating disease in response to pathogenic CD4 T cell activation. We hypothesize that the CD8 Treg network is dysfunctional in patients with Celiac and Crohn’s disease, allowing pathogenic CD4 T cell expansion, the initiation of a cascade of inflammatory pathological consequences and the perpetuation of tissue destructive inflammation in Celiac disease and IBD. Here we dem
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Li, Rong, Juan Xu, Ming Wu та ін. "Circulating CD4+ Treg, CD8+ Treg, and CD3+ γδ T Cell Subpopulations in Ovarian Cancer". Medicina 59, № 2 (2023): 205. http://dx.doi.org/10.3390/medicina59020205.

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Background and Objectives: Regulatory T cells (Tregs) are usually enriched in ovarian cancer (OC), and their immunosuppressive function plays a key role in tumorigenesis and progression. We mainly explored the phenotypical characterization of Treg-related markers on αβ and γδ T cell subsets in patients with OC. Materials and Methods: Thirty-six untreated patients with OC at the Women’s Hospital of Nanjing Medical University from September 2019 to August 2021 were enrolled. Phenotypical characterization of Tregs-related markers were detected by flow cytometry (FCM). Enzyme-linked immunosorbent
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Yamagami, Wataru, Nobuyuki Susumu, Hideo Tanaka, et al. "Immunofluorescence-Detected Infiltration of CD4+FOXP3+ Regulatory T Cells is Relevant to the Prognosis of Patients With Endometrial Cancer." International Journal of Gynecologic Cancer 21, no. 9 (2011): 1628–34. http://dx.doi.org/10.1097/igc.0b013e31822c271f.

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ObjectiveHost antitumor immune responses are associated with many types of immune cells and soluble components. In particular, CD8+ cytotoxic T lymphocytes (CTLs) play a central role. Regulatory T cells (Tregs) have been reported to induce tumor immune tolerance in various cancers. In the present study, we evaluated lymphocytic infiltration in endometrial cancer tissue to clarify its relationship with clinicopathological factors and the prognosis of patients.MethodsThe study included 53 patients whose condition was diagnosed as endometrial cancer between 1994 and 2004 at Keio University hospit
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Rozprawy doktorskie na temat "CD8+ Treg cells"

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Durost, Philip A. "Evaluation of IL2 and HLA on the Homeostasis and Function of Human CD4 and CD8 T Cells." eScholarship@UMMS, 2009. http://escholarship.umassmed.edu/gsbs_diss/936.

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Homeostasis of human T cells is regulated by many factors that control proliferation, differentiation of effector cells and generation of memory. Our current knowledge of the mechanisms controlling human T cell homeostasis in vivo is based on experiments in small animal models. However many differences exist between immune systems of mice and humans, including cell composition, function, and gene expression. Humanized mouse models have shown great value in the study of human immunobiology. I have used novel humanized mouse models to examine the role of human MHC (HLA) and human IL2 in CD8 T ce
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Durost, Philip A. "Evaluation of IL2 and HLA on the Homeostasis and Function of Human CD4 and CD8 T Cells." eScholarship@UMMS, 2017. https://escholarship.umassmed.edu/gsbs_diss/936.

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Homeostasis of human T cells is regulated by many factors that control proliferation, differentiation of effector cells and generation of memory. Our current knowledge of the mechanisms controlling human T cell homeostasis in vivo is based on experiments in small animal models. However many differences exist between immune systems of mice and humans, including cell composition, function, and gene expression. Humanized mouse models have shown great value in the study of human immunobiology. I have used novel humanized mouse models to examine the role of human MHC (HLA) and human IL2 in CD8 T ce
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Huang, Wenting. "Immunology and Genetics of Autoimmune Biliary Disease." University of Cincinnati / OhioLINK, 2015. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1447691320.

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Polak, Katarzyna. "Role of the Eos and Helios transcription factors in regulatory T cell biology." Thesis, Strasbourg, 2015. http://www.theses.fr/2015STRAJ011/document.

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Les facteurs de transcription Eos et Helios ont été décrits comme étant des modulateurs des fonctions des cellules T régulatrices (Treg). Nos résultats suggèrent qu’Eos et Helios ne sont pas nécessaires, ni pour la différenciation, ni pour les principales fonctions des cellules Treg CD4+. Cependant, les cellules Helios-/- présentent une meilleure activité suppressive et à un profil transcriptomique de cellules Treg activées. Pour tester si Eos et Helios coopèrent pour réguler les fonctions des cellules Treg, nous avons analysé les souris doubles mutantes. Nos découvertes indiquent que la perte
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Fernandes, Reginaldo Keller [UNESP]. "Alterações transcricionais em células dendríticas e células T CD4+ humanas em resposta ao Paracoccidioides brasiliensis." Universidade Estadual Paulista (UNESP), 2017. http://hdl.handle.net/11449/150253.

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Submitted by REGINALDO KELLER FERNANDES null (regiskeller@msn.com) on 2017-04-12T12:10:23Z No. of bitstreams: 1 Tese Dr definitiva.pdf: 5601863 bytes, checksum: 50eec58640e31a0c12ce54dde368d5a3 (MD5)<br>Approved for entry into archive by Luiz Galeffi (luizgaleffi@gmail.com) on 2017-04-17T20:28:15Z (GMT) No. of bitstreams: 1 fernandes_rk_dr_bot.pdf: 5601863 bytes, checksum: 50eec58640e31a0c12ce54dde368d5a3 (MD5)<br>Made available in DSpace on 2017-04-17T20:28:15Z (GMT). No. of bitstreams: 1 fernandes_rk_dr_bot.pdf: 5601863 bytes, checksum: 50eec58640e31a0c12ce54dde368d5a3 (MD5) Previous
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Fernandes, Reginaldo Keller. "Alterações transcricionais em células dendríticas e células T CD4+ humanas em resposta ao Paracoccidioides brasiliensis." Botucatu, 2017. http://hdl.handle.net/11449/150253.

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Orientador: Ângela Maria Victoriano de Campos Soares<br>Resumo: A paracoccidioidomicose (PCM) é uma micose sistêmica endêmica na América Latina, principalmente no Brasil, Argentina e Venezuela, e que promove um importante impacto na saúde pública. Seu agente etiológico é um fungo termodimórfico pertencente ao gênero Paracoccidioides que compreende o Paracocidioides brasiliensis (Pb) e suas espécies crípticas S1, PS2, PS3 e Paracoccidioides lutzii. As consequências da interação do fungo com as células da resposta imune inata, tais como as células dendríticas (DC), destacando a capacidade destas
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Sérazin, Céline. "Raffinement de l'identité des lymphocytes T régulateurs CD8+ chez l'Homme grâce à l'utilisation des technologies multi-omiques." Thesis, Nantes Université, 2022. http://www.theses.fr/2022NANU1016.

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Les cellules T régulatrices CD8+ (Tregs) ont été les premières cellules suppressives signalées en 1970, mais elles ont été mises de côté pendant des années en raison du manque de marqueurs permettant de les définir correctement. Notre équipe a démontré que les Tregs CD8+ identifiés par une expression faible et/ou négative de CD45RC, une des isoformes de la molécule CD45, montrent une puissante activité suppressive in vitro et in vivo, alors que les cellules exprimant des niveaux élevés de CD45RC ne le font pas. Dans cet article, nous nous sommes penchés sur l'hétérogénéité au sein des lymphocy
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Akamatsu, Masahiko. "Conversion of antigen-specific effector/memory T cells into Foxp3-expressing Treg cells by inhibition of CDK8/19." Kyoto University, 2020. http://hdl.handle.net/2433/253464.

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Varikuti, Sanjay. "Role of CD4+CD25+ Regulatory T Lymphocytes in Experimental Toxoplasmosis." TopSCHOLAR®, 2009. http://digitalcommons.wku.edu/theses/113.

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Toxoplasmosis is an important cause of congenital disease, and it is one of the most common opportunistic infections in patients with acquired immunodeficiency syndrome. The need for a reliable experimental model of this infection is crucial not only for achieving a better understanding of the patho-physiology of the disease, but also for developing better methods for evaluating new therapeutic regimens. The purpose of the present study was to investigate the role of CD4+CD25+ T regulatory lymphocytes in mice infected with Toxoplasma gondii. T regulatory (Treg) cells have been shown to play an
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Ebner, Friederike. "The role of microglia phenotypes in modulating CD4 + T cell responses." Doctoral thesis, Humboldt-Universität zu Berlin, Mathematisch-Naturwissenschaftliche Fakultät I, 2014. http://dx.doi.org/10.18452/16882.

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Die Invasion von Leukozyten in das zentrale Nervensystem (ZNS) ist ein wesentlicher Bestandteil bei der Pathogenese von Hirnverletzungen sowie akuten und chronischen Entzündungsvorgängen im Gehirn. Mikrogliazellen, die überwiegende Population immunkompetenter Zellen des ZNS, stellen die erste Verteidigungslinie im Hinblick auf Verletzungen und Erkrankungen des Gehirns dar. Im Rahmen vieler neurodegenerativer Erkrankungen wird die Zerstörung von Neuronen, aber auch die kollaterale Gewebsschädigung auf die Aktivierung der Mikrogliazellen zurückgeführt. Die vorliegende Arbeit beschreibt erstmali
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Części książek na temat "CD8+ Treg cells"

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Multhoff, G., E. A. Repasky, and Peter Vaupel. "Mild Hyperthermia Induced by Water-Filtered Infrared A Irradiation: A Potent Strategy to Foster Immune Recognition and Anti-Tumor Immune Responses in Superficial Cancers?" In Water-filtered Infrared A (wIRA) Irradiation. Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-030-92880-3_10.

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AbstractApart from a number of positive “physiological” effects such as an increase in local blood flow which results in an improved oxygen supply and a reversal of tumor hypoxia, a key hallmark of cancer growth which greatly impairs anti-tumor immune responses, hyperthermia (HT) also exerts beneficial effects on anti-cancer immunity. The water-filtered infrared A (wIRA) irradiation technique achieves tissue temperatures in the fever-range (tT = 39–41 °C) or mild hyperthermia levels (tT = 39–43 °C) up to tissue depths of ≈25 mm in tissues. At tissue temperatures of 39–43 °C, by fostering the r
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Chou, Chon-Kit, and Xin Chen. "Preferential Expansion of CD4+Foxp3+ Regulatory T Cells (Tregs) In Vitro by Tumor Necrosis Factor." In Methods in Molecular Biology. Springer US, 2020. http://dx.doi.org/10.1007/978-1-0716-0266-9_6.

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Jebbawi, Fadi, Hussein Fayyad-Kazan, Makram Merimi, et al. "A microRNA Profile of Human CD8+ Regulatory T cells and Characterization of the Effects of microRNAs on Treg Cell-Associated Genes." In Immunology and Cancer Biology. Vide Leaf, Hyderabad, 2020. http://dx.doi.org/10.37247/imcac.1.2020.2.

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Schallenberg, Sonja, Cathleen Petzold, Julia Riewaldt, and Karsten Kretschmer. "Regulatory T Cell-Based Immunotherapy." In Medical Advancements in Aging and Regenerative Technologies. IGI Global, 2013. http://dx.doi.org/10.4018/978-1-4666-2506-8.ch006.

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CD4+CD25+ regulatory T (Treg) cells expressing the forkhead box transcription factor Foxp3 have a vital function in the maintenance of immune homeostasis and the prevention of fatal multi-organ autoimmunity throughout life. In the last decade, Foxp3+ Treg cells have raised the hope for novel cell-based therapies to achieve tolerance in clinical settings of unwanted immune responses such as autoimmunity and graft rejection. Conceptually, the antigen-specific enhancement of Treg cell function is of particular importance because such strategies will minimize the requirements for pharmaceutical im
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Gu, Chao, and SangKon Oh. "Type 1 Regulatory T Cells and Their Application in Cell Therapy." In Regulatory T Cells [Working Title]. IntechOpen, 2022. http://dx.doi.org/10.5772/intechopen.106852.

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Critical roles of regulatory T cells (Tregs) in the maintenance of immune homeostasis by controlling unwanted types of immune responses have been well documented. Therefore, Treg-based therapeutic strategies for inflammatory diseases have long been investigated. Type 1 regulatory T (Tr1) cells and Foxp3+ Tregs are two major subsets of regulatory CD4+ T cells. In contrast to Foxp3+ Tregs, the master transcription regulator for Tr1 cells still remains elusive. Nevertheless, Tr1 cells are generally defined as a specialized subset of CD4+ T cells, which are induced in the periphery during antigen
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Lu, Chunxia, Anil Kumar Pasupulati, Carey Lumeng, Yong Fan, Mark A. Sperling, and Ram K. Menon. "Targeted Abrogation of Growth Hormone (GH) Action in Macrophages Impairs Insulin Sensitivity and Decreases CD4+FoxP3+T (Treg) Cells in Adipose Tissue." In BASIC/TRANSLATIONAL - Growth Hormone & Prolactin. The Endocrine Society, 2011. http://dx.doi.org/10.1210/endo-meetings.2011.part2.p35.p2-324.

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Streszczenia konferencji na temat "CD8+ Treg cells"

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Sugiyama, Daisuke, Tomoaki Muramatsu, Yoichi Kobayashi, et al. "Abstract 3289: The status of the tumor microenvironment changes dynamics of the balance of CD8+T cells and Treg cells in renal cell carcinoma." In Proceedings: AACR Annual Meeting 2020; April 27-28, 2020 and June 22-24, 2020; Philadelphia, PA. American Association for Cancer Research, 2020. http://dx.doi.org/10.1158/1538-7445.am2020-3289.

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Gandhi, Shipra, Manu Pandey, Kristopher M. Attwood, et al. "Abstract 4057: Measurement of myeloid derived suppressor cells (MDSC), T regulatory cells (Treg), CD8+and CD4+T-cells, and cytokines/chemokines in patients with metastatic melanoma treated with pembrolizumab and propranolol." In Proceedings: AACR Annual Meeting 2019; March 29-April 3, 2019; Atlanta, GA. American Association for Cancer Research, 2019. http://dx.doi.org/10.1158/1538-7445.sabcs18-4057.

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Gandhi, Shipra, Manu Pandey, Kristopher M. Attwood, et al. "Abstract 4057: Measurement of myeloid derived suppressor cells (MDSC), T regulatory cells (Treg), CD8+and CD4+T-cells, and cytokines/chemokines in patients with metastatic melanoma treated with pembrolizumab and propranolol." In Proceedings: AACR Annual Meeting 2019; March 29-April 3, 2019; Atlanta, GA. American Association for Cancer Research, 2019. http://dx.doi.org/10.1158/1538-7445.am2019-4057.

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Cillo, Anthony R., Christopher A. Chuckran, Mengting Liao, et al. "Abstract TMIM-063: TARGETING NEUROPILIN-1+ T REGULATORY CELLS IN PATIENTS WITH HIGH GRADE SEROUS OVARIAN CANCER DECREASES TREG-SPECIFIC SUPPRESSION OF CD8+ T CELLS." In Abstracts: 12th Biennial Ovarian Cancer Research Symposium; September 13-15, 2018; Seattle, Washington. American Association for Cancer Research, 2019. http://dx.doi.org/10.1158/1557-3265.ovcasymp18-tmim-063.

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Wang, Baohui, Hailin Wang, Tingting Li, et al. "841 LBL-019, a novel TNFR2 agonist antibody, shows potent anti-tumor efficacy through preferentially activating CD8+ T cells and alleviating the suppressive effect of Treg cells." In SITC 38th Annual Meeting (SITC 2023) Abstracts. BMJ Publishing Group Ltd, 2023. http://dx.doi.org/10.1136/jitc-2023-sitc2023.0841.

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Paustian, Amanda Schmidt, Linlin Guo, Weiguo Feng, et al. "752 CCR8-targeted Treg depletion and PD-1 blockade combine to divert CD8+ T cells from exhaustion associated transcriptional trajectories within the tumor microenvironment." In SITC 39th Annual Meeting (SITC 2024) Abstracts. BMJ Publishing Group Ltd, 2024. http://dx.doi.org/10.1136/jitc-2024-sitc2024.0752.

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Yang, Mingcan, Zetao Liao, Yutong Jiang, and Jieruo Gu. "AB0036 THE IMPACT OF ANTI-TNF THERAPY ON CD4+T CELL SUBSETS IN DIFFERENT DIFFERENTIATION STAGES AND TREG CELLS IN ACTIVE ANKYLOSING SPONDYLITIS." In Annual European Congress of Rheumatology, EULAR 2019, Madrid, 12–15 June 2019. BMJ Publishing Group Ltd and European League Against Rheumatism, 2019. http://dx.doi.org/10.1136/annrheumdis-2019-eular.5708.

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Palmeri, Joseph R., Brianna M. Lax, Josh M. Peters, et al. "1224 Tregs constrain CD8+T cell priming required for curative intratumorally anchored anti-4–1BB immunotherapy." In SITC 38th Annual Meeting (SITC 2023) Abstracts. BMJ Publishing Group Ltd, 2023. http://dx.doi.org/10.1136/jitc-2023-sitc2023.1224.

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Van Berckelaer, Christophe, Charlotte Rypens, Steven Van Laere, et al. "Abstract P5-04-04: The spatial interactions between FOXP3+ Tregs, CD8+ cytotoxic T cells and tumor cells predict response to therapy and prognosis in inflammatory breast cancer." In Abstracts: 2019 San Antonio Breast Cancer Symposium; December 10-14, 2019; San Antonio, Texas. American Association for Cancer Research, 2020. http://dx.doi.org/10.1158/1538-7445.sabcs19-p5-04-04.

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Duan, Yanan, Hong-Yan Wen, Yang Liu, et al. "SAT0013 CHANGES AND SIGNIFICANCE OF CD4+CD25+FOXP3+TREG CELLS IN THE PERIPHERAL BLOOD OF PATIENTS WITH AUTOIMMUNE DISEASES." In Annual European Congress of Rheumatology, EULAR 2019, Madrid, 12–15 June 2019. BMJ Publishing Group Ltd and European League Against Rheumatism, 2019. http://dx.doi.org/10.1136/annrheumdis-2019-eular.5530.

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